SENTHIL KUMAR AIYAPPAN

@srmist.edu.in

PROF AND HOD, RADIODIAGNOSIS
SRM INSTITUTE OF SCIENCE AND TECHNOLOGY

SENTHIL KUMAR AIYAPPAN


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https://researchid.co/senthila1
64

Scopus Publications

506

Scholar Citations

12

Scholar h-index

16

Scholar i10-index

Scopus Publications

  • Automated deep learning pipeline for measuring lumbar thecal sac AP diameter on mid-sagittal MR images
    Akash Nixon, Victor Rakesh Lazar, Saikiran Pendem, Karan Sekar, Senthil Kumar Aiyappan, Sundara Raja Perumal
    BMC Medical Imaging, 2026
    OBJECTIVE: To develop and validate an automated, disc-level deep learning pipeline for quantitative measurement of anteroposterior (AP) thecal sac diameter on mid-sagittal lumbar T2-weighted MRI. MATERIALS AND METHODS: In this retrospective study, 511 mid-sagittal lumbar T2 MRI examinations were included after screening 758 cases and applying predefined exclusions. The workflow combined YOLOv8 oriented bounding boxes (OBB) for disc-level localization and orientation estimation, homography-based ROI warping, Attention U-Net segmentation, and skeleton-based AP diameter computation in millimeters using DICOM pixel spacing. Validation was performed on internal (50) and external (50; RSNA 2024 lumbar dataset) cohorts with two radiologists providing the reference standard. RESULT: Inter-reader agreement was excellent (ICC (2, 1) = 0.967; 711 paired measurements). Against the reader-mean reference, the pipeline achieved an overall MAE of 0.994 mm (711 disc-level measurements). Internal validation showed MAE 0.909 mm (357 measurements) and external validation MAE 1.079 mm (354 measurements). Severity-wise MAE remained ~ 1 mm (mild 0.930 mm; moderate 1.234 mm; severe 1.038 mm). Automatic disc-level labeling was performed, and OBB-derived orientation significantly improved AP measurement-line validity versus axis-aligned detection (acceptable lines 99.02% vs. 77.64%). CONCLUSION: An orientation-aware YOLOv8-OBB + Attention U-Net pipeline enables automated, disc-level AP thecal sac diameter quantification on mid-sagittal lumbar MRI with ~ 1 mm error relative to expert reference, supporting standardized morphometric reporting and measurement-driven assessment of lumbar stenosis.
  • Diagnostic Utility of Apparent Diffusion Coefficient Values of Spleen and Liver in Assessment of Severity of Portal Hypertension and Liver Cirrhosis
    Kommuri Siddhardha, S. Jalaludheen, Senthil Kumar Aiyappan
    Nigerian Postgraduate Medical Journal, 2026
    Background: Portal hypertension (PH) is a significant effect of chronic liver disease (CLD), resulting in variceal haemorrhage, ascites and hypersplenism. Apparent diffusion coefficient (ADC) and diffusion-weighted imaging (DWI) values serve as potential non-invasive indicators for evaluating the PH and liver fibrosis. Aims: This study evaluated the impact of portal hypertension on the ADC values of the liver and spleen and related PH severity with the Child-Pugh score. Materials and Methods: A cross-sectional study was performed with individuals exhibiting clinical and radiological indications of CLD and PH and also with healthy controls. Magnetic resonance imaging was employed to assess spleen and liver ADC values, which were linked with clinical severity of diseases. Results: Liver ADC levels were substantially reduced among patients with cirrhosis when compared with controls, suggesting the existence of fibrosis. Conversely, spleen ADC values were elevated in affected patients, signifying splanchnic congestion. A particular spleen ADC level showed elevated sensitivity and specificity for detecting severe illness. Liver ADC reduced and spleen ADC enhanced with worsening Child–Pugh classification. An increased spleen ADC correlated with variceal hypersplenism and haemorrhage. Conclusion: DWI-derived ADC values constitute a non-invasive, reliable method for assessing liver fibrosis and the severity of PH, hence validating their application in clinical evaluation and early management for patients with CLD.
  • Severity Assessment of Acute Pancreatitis Using the Modified Computed Tomography Severity Index and Revised Atlanta Classification: Correlation with Bedside Index for Severity in Acute Pancreatitis Clinical Scoring
    Mandadapu Sri Padma, Kaavya Bandari, Yeshwanth Raju Narayanan, Senthil Kumar Aiyappan
    Nigerian Postgraduate Medical Journal, 2026
    Background: Acute pancreatitis (AP) is a pancreatic inflammatory condition characterised by a varied clinical course, ranging from mild self-limiting episodes to severe disorder associated with significant morbidity and mortality. Proper severity evaluation is crucial for prompt intervention and enhanced outcomes. Aims: This study assesses the efficacy of the Modified Computed Tomography (CT) Severity Index (MCTSI) and Revised Atlanta Classification (RAC) in conjunction with the Bedside Index for Severity in AP (BISAP) for evaluating disease severity and forecasting clinical outcomes. Methods: A cross-sectional observational study was performed at SRM Medical College Hospital involving 45 patients with AP. BISAP was carried out following 24 h of admission, whereas MCTSI was evaluated using contrast-enhanced CT. Severity was categorised utilising RAC, and clinical-radiological connections were examined. Results: RAC indicated that 40%, 46.7% and 11.1% of patients encountered mild, moderately severe and severe AP, respectively. The mean BISAP and MCTSI scores were 1.8 ± 0.9 and 6.1 ± 2.3, respectively. Despite individual variations in raw scores, correlation analysis employing Spearman’s rank test revealed a statistically significant moderate positive correlation between BISAP and MCTSI (rho = 0.563, P < 0.01). This suggests that as BISAP ratings escalated, MCTSI levels similarly increased, demonstrating a correlation between the two scoring systems in assessing illness severity. Conclusion: BISAP and MCTSI provide combined advantages in predicting the severity of AP. The RAC continues to be a reliable classification system. The integration of clinical and imaging methods improves early risk assessment and leads to appropriate care.
  • Multimodal MRI and PET /SPECT Brain Image Integration for improved clinical diagnosis of PACS in Health care
    Saravanan Vijayan, Malarvizhi Subramani, Senthil Kumar Aiyappan
    Ksii Transactions on Internet and Information Systems, 2025
    Multimodal medical image fusion is an essential technological advancement in medical diagnosis that integrates data from several image modalities, giving clinicians an improved visual perception for earlier illness identification.This work aims to improve the computeraided diagnosis CAD system using image processing.We propose a two-level decomposition method utilizing Discrete Wavelet Transform (DWT) and Non-subsampled Contourlet Transform (NSCT) for MRI-SPECT/PET image fusion for improved visual quality.In the subsequent stage, the phase components PC of the images were computed and combined with the first stage output.A final single fused image with good clarity and sharpness is obtained by applying inverse transforms, which helps doctors for quicker identification and diagnosis of brain tumour diseases.This consecutive stage of decomposition along with phase congruency provides an in-depth analysis of frequency components of source images with edge retention which helped in extracting the soft cell portions and tumour-affected portions effectively with less computational complexity than the other related articles including the recent deep learning techniques.Images of brain diseases in the Whole Brain Atlas dataset and real-time test cases of MRI and SPECT images were taken for performance study and got subjective assessment verified with the radiologist.Qualitative and quantitative metrics were computed with similar works and our proposal provides an improvement of visual quality parameters.The experimental analysis proved that the effectiveness of our fusion approach outperformed well compared to existing methodologies.Our algorithm can be deployed with the existing PACS.
  • Europium-doped cerium oxide nanoparticle-impregnated Hyalgan® (CartiOxgel): an intra-articular contrast agent for X-ray CT and optical imaging
    Hema Brindha Masanam, Sina Jafari, Ashwin Kumar Narasimhan, Priyatha Premanth, Margaret Salomi, Victor R. Lazar, Sentil Kumar Aiyappan, Sruthi Ann Alex
    Rsc Advances, 2025
    CartiOxgel, a hybrid nano-contrast agent (EuC NPs in Hyalgan®), shows superior contrast and visibility in live X-ray CT imaging of Wistar rat knees post intra-articular injection, compared to commercial Omnipaque™ iodine.
  • Post Contrast-Acute Kidney Injury in CT Imaging: A Knowledge, Perception and Practice Assessment among Radiographers and Radiologists
    Punitha Pavadai, Victor Rakesh Lazar, Kirthi Sathyakumar, Senthil Kumar Aiyappan, Preethi Baskar, et al.
    Giornale Italiano Di Nefrologia, 2025
    This research highlights the important roles of radiologists and radiographers in managing and preventing PC-AKI. There are significant knowledge gaps, particularly in emergency situations and when dealing with pregnant or paediatric patients. Radiographers, in particular, demonstrate a lack of understanding regarding PC-AKI prevention, indicating a need for specialized training.
  • Beyond the Surface: Delving Deeper Into Leukoaraiosis With Multivoxel Magnetic Resonance Spectroscopy
    Ragitha Ramesh, Arunan Subbiah, Senthilkumar Aiyappan, Sabari Ramesh
    Innovative Medicine of Kuban, 2025
    Objective: To investigate metabolite changes in patients with leukoaraiosis employing multivoxel magnetic resonance spectroscopy (MRS) with the focus on periventricular white matter and explicate the biochemical alterations associated with leukoaraiosis and their impact on lesion load.Methods: This prospective study was conducted on 64 patients with a known history of leukoaraiosis (mean age, 66.40±8.96 years; 54 men and 10 women) referred for magnetic resonance imaging, wherein MRS was performed. For comparison, 128 age- and gender-matched healthy individuals (mean age, 61.98±8.18 years; 40 men and 88 women) who comprised the control group also underwent MRS. We correlated metabolite ratios (NAA/Cr, NAA/Cho, and Cho/Cr) analyzed on MRS with lesion load measured by semiautomated software.Results: The NAA/Cr ratio was significantly lower, whereas the NAA/Cho ratio was significantly higher in the control group compared with the patients with leukoaraiosis (P <.0001) . The Cho/Cr ratio was also significantly higher in the controls compared with the patients with leukoaraiosis (P <.0034) . This suggests that patients with leukoaraiosis exhibit significant metabolic differences compared with healthy controls. We observed no correlation between the metabolite ratios and lesion load, which indicates that the degree of white matter hyperintensities is not related to the metabolic changes in leukoaraiosis.Conclusions: This study explicates the understanding of leukoaraiosis and underscores the potential of MRS as a biomarker for early diagnosis of leukoaraiosis.
  • Extensive retroperitoneal lymphangiectasia presenting as inguinal swelling
    Deepthi Arun Kumar, Senthil Kumar Aiyappan, Kshitija Narayan Vinchurkar, Revathi Rajagopal
    BMJ Case Reports, 2024
    A male in his early 20s presented with bilateral groin swelling for 2 months, more pronounced on the left, worsening with activity and subsiding at rest. He had no urinary or constitutional symptoms, past surgeries or trauma history. On examination, the patient had bilateral inguinal region
  • Imaging findings of granulosa cell tumour of right ovary with rupture and torsion presenting as acute abdomen
    Deepthi Arun Kumar, Senthil Kumar Aiyappan
    BMJ Case Reports, 2024
    A multiparous woman in her late 40s presented to the gynaecological outpatient department with sudden right iliac fossa pain, vomiting and one febrile episode. She had regular menstrual cycles, with her last period 10 days prior to the presentation. On examination, the patient was pale, with
  • Mitochondrial Membrane Protein-Associated Neurodegeneration with Brain Iron Accumulation: Diagnosis by MRI
    Senthil Kumar Aiyappan, Shriram Natarajan, S Robert Wilson, Kondampally Varsha Reddy
    Neurology India, 2024
    Sir, An 11-year-old girl child first born to second-degree consanguineous parents presented with complaints of twisting of foot intermittently during walking involving both legs randomly since 9 months. There was no associated fall or history of difficulty in walking or getting up from a squatting position. The patient had no history of seizures or difficulty in performing daily fine motor activities. No other relevant medical or surgical history could be elicited. Upon examination, the patient was afebrile, and vitals were stable. Routine blood and urine examination investigations were within normal limits. A central nervous system examination was performed, and the findings are elaborated below. There was withdrawal to painful stimulus and grimace to pain. No cerebellar signs were noted. Cortical sensations could not be tested. The autonomic system was normal. Spine was stiff and the child could walk without support with a rigid neck and spine. Superficial reflexes were present, with plantar being extensor. Deep tendon reflexes were brisk. There was no bladder or bowel involvement. No muscle wasting was noted. After clinical examination, the possibility of pyramidal and extrapyramidal tract involvement was kept, and the patient was subjected to further investigations. Investigations such as serum ceruloplasmin and urine copper were under normal limits. Nerve conduction study and electroencephalogram were normal. Fundus examination were normal. Psychiatric evaluation was performed, which showed no significant abnormality. Ultrasound of the abdomen was normal with no organomegaly. Magnetic resonance imaging (MRI) of brain plain and whole spine screening was performed. MRI of the brain showed T2 hypo intensity with significant blooming on susceptibility-weighted images in the globus pallidus and substantia nigra, which was not hyperdense on noncontrast CT suggestive of iron deposition [Figure 1a-d]. A diagnosis of neurodegeneration with brain iron accumulation was made. T2 hyperintense streak of the medial medullary lamina at the level of anterior commissure was preserved, suggestive of mitochondrial membrane protein-associated degeneration variant of Neurodegeneration with brain iron accumulation (NBIA) [Figure 2a-c]. The area also showed mild T1 hyperintensity suggestive of paramagnetic substance deposition [Figure 2d]. MRI whole spine screening was normal. Whole exome with whole mitochondrial genome sequencing was performed, which confirmed the diagnosis. The patient was managed symptomatically.Figure 1: (a and b) Axial susceptibility-weighted images show gradient blooming in bilateral basal ganglia and substantia nigra with preservation of isointense signal in the middle (medial medullary laminae) of inner and outer layers of iron accumulation in globus pallidus (white arrows). (c) Axial T2 weighted image showing subtle T2 hypointensity of globus pallidus (black arrow). (d) Noncontrast CT images showing normal basal ganglia (black arrow)Figure 2: (a) Axial T2 and (b) susceptibility-weighted images showing T2 hyperintense streak in medial medullary laminae of globus pallidus, which appeared spared on susceptibility-weighted images (white arrows). (c) Coronal T2 weighted images show T2 hyperintense streak in medial medullary laminae of globus pallidus (white arrow) (d) Sagittal T1 weighted images show mild T1 hyperintensity of basal ganglia suggestive of substance deposition (black arrow)NBIA is a group of inherited neurologic disorders characterized by the abnormal accumulation of iron in the basal ganglia, most often in the globus pallidus and/or substantia nigra. Generalized cerebral atrophy and cerebellar atrophy are frequently observed. In our case, there was no cerebral or cerebellar atrophy. The four most common NBIA disorders are pantothenate kinase-associated neurodegeneration (PKAN) due to mutations in PANK2, phospholipase A2-associated neurodegeneration caused by mutation in PLA2G6, mitochondrial membrane protein-associated neurodegeneration from mutations in C19orf12, and beta-propeller protein-associated neurodegeneration due to mutations in WDR45.[1] Our case was mitochondrial membrane protein-associated neurodegeneration from mutations in C19orf12. The usual clinical manifestations of NBIA are progressive dystonia, dysarthria, spasticity, parkinsonism, neuropsychiatric abnormalities, and optic atrophy or retinal degeneration.[2] Mitochondrial membrane protein-associated neurodegeneration (MPAN) is an autosomal recessive disease caused by mutations in C19orf12 gene. MPAN is considered a synucleinopathy, with lewy bodies and lewy neurites in basal ganglia and neocortex. The disease may manifest from the first decade of life to adulthood. The most common features are gait changes, early lower limb spasticity and extensor plantar response.[3] Our case had gait changes and extensor plantar response. Other symptoms include dysarthria, dystonia, optic atrophy, neuropsychiatric abnormalities and cognitive decline which was not present in our case.[2] The disease progression is slow and lifespan is usually long in most of the cases. Brain MRI shows iron accumulation in substantia nigra and globus pallidus on susceptibility weighted sequences, normally without the eye of the tiger sign, which is typically found in PKAN. The characteristic imaging finding in MPAN on brain MRI from which it can be differentiated from other NBIA include T2 hyperintense linear signal in the medial medullary laminae at the level of anterior commissure, which is located in between the segments of the globus pallidus like in our case.[3] Declaration of patient consent The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed. Financial support and sponsorship Nil. Conflicts of interest There are no conflicts of interest.
  • Correlation of placental thickness with gestational age in second and third trimester using ultrasonography
    Kshitija Narayan Vinchurkar, Senthil Kumar Aiyappan, C. Prem Kumar, Vinayagam Shanmugam, Aparajita Singh
    Egyptian Journal of Radiology and Nuclear Medicine, 2023
  • Anomalous origin of the left coronary artery from the right sinus of Valsalva with separate ostia and inter-arterial course: MDCT angiography depiction
    Deepthi Arun Kumar, Senthil Kumar Aiyappan
    Indian Journal of Thoracic and Cardiovascular Surgery, 2023
  • Congenital Infiltrating Lipomatosis of Face Associated with Ipsilateral Hemimegalencephaly: An Uncommon Cause for Facial Asymmetry in a Child
    S. Aiyappan, V. Shanmugam
    Neurology India, 2023
  • Invasive intracholecystic papillary neoplasm of gall bladder with perforation: A case report
    Patel Ruchik Anilbhai, Shakthepriya Kannan Narayanan, Kalaivani Amitkumar, Senthil Kumar Aiyappan
    Tropical Journal of Pharmaceutical Research, 2021
  • Xanthogranulomatous Urachitis
    Senthil Kumar Aiyappan, Kshitija Narayan Vinchurkar, Vinayagam Shanmugam
    Indian Journal of Surgery, 2021
  • Falciform Ligament Torsion Presenting as Acute Abdomen
    Senthil Kumar Aiyappan, Krishnaprasanthi Padala, Subhalakshmi Kumaran, Vinayagam Shanmugam
    Indian Journal of Surgery, 2021
  • Giant left ventricular outflow tract pseudoaneurysm presenting as anterior mediastinal mass: diagnosis by MDCT
    Senthil Kumar Aiyappan, Vinisha Kamadana, Patel Ruchik Anilbhai, Kshitija Narayan Vinchurkar
    Indian Journal of Thoracic and Cardiovascular Surgery, 2020
  • Lupus enteritis
    Senthil Kumar Aiyappan, Akhilesh Suvindran
    Pan African Medical Journal, 2019
  • Role of gray scale, color doppler and spectral doppler in differentiation between malignant and benign thyroid nodules
    Manoj Kumar Palaniappan
    Journal of Clinical and Diagnostic Research, 2016
  • Age-related normogram for ovarian antral follicle count in women with polycystic ovary syndrome and comparison with age matched controls using magnetic resonance imaging
    Senthil Kumar Aiyappan
    Journal of Clinical and Diagnostic Research, 2016
  • A Case of Exophytic Angiomyolipoma of the Liver
    Senthil Kumar Aiyappan, Upasana Ranga, Saveetha Veeraiyan
    Indian Journal of Surgery, 2015
  • Omental infarct mimicking acute pancreatitis
    Senthil Kumar Aiyappan, Upasana Ranga, Saveetha Veeraiyan
    Indian Journal of Surgery, 2015
  • A Case of Dermatofibrosarcoma Protuberans of the Trunk
    Senthil Kumar Aiyappan, Upasana Ranga, Anita Samraj, Saveetha Veeraiyan
    Indian Journal of Surgery, 2015
  • Unusual Cause of Suprasternal Swelling: Cervical Extension with Herniation of Mediastinal Thymus
    Upasana Ranga, Senthil Kumar Aiyappan, Balamma Sujatha, Ambika Pathy, Saveetha Veeraiyan
    Indian Journal of Pediatrics, 2015
  • Disappearing lytic lesion of skull
    Senthil Kumar Aiyappan, Upasana Ranga, Benjamin M. Sagayaraj, Saveetha Veeraiyan
    Journal of Neurosciences in Rural Practice, 2015
  • A rare case of bilateral nasal block
    Indian Journal of Medical Research Supplement, 2015
  • Partially thrombosed aneurysm of external jugular vein mimicking cervical lymphadenopathy
    Senthil Kumar Aiyappan, Upasana Ranga
    Journal of Mechanical Science and Technology, 2015
  • Neurofibromatosis type 2: Intracranial calcifications as a clue to diagnosis
    Senthil Kumar Aiyappan, Upasana Ranga, Saveetha Veeraiyan
    Journal of Neurosciences in Rural Practice, 2015
  • Idiopathic subareolar breast abscess in a male patient
    Senthil Kumar Aiyappan
    Journal of Clinical and Diagnostic Research, 2015
  • Double fistula: Bronchopleural and pleurocutaneous
    Upasana Ranga, SenthilKumar Aiyappan, Saveetha Veeraiyan
    Lung India, 2015
  • Solitary right coronary artery aneurysm with anomalous origin of left coronary artery
    Senthil Kumar Aiyappan, Upasana Ranga, Saveetha Veeraiyan
    Journal of Mechanical Science and Technology, 2015
  • Single coronary artery from right sinus of valsalva associated with atrial septal defect
    Senthil Kumar Aiyappan, Upasana Ranga, Saveetha Veeraiyan
    Indian Journal of Thoracic and Cardiovascular Surgery, 2014
  • Bronchoscopic removal of aspergilloma from a cavitary lesion of the lung
    Kalyan Kumar P.V
    Journal of Clinical and Diagnostic Research, 2014
  • Incidentally detected congenital left atrial appendage aneurysm
    Senthil Kumar Aiyappan, Upasana Ranga, Saveetha Veeraiyan
    Indian Journal of Thoracic and Cardiovascular Surgery, 2014
  • A case of facial puffiness
    Senthil Kumar Aiyappan, Upasana Ranga, Saveetha Veeraiyan
    Journal of Emergency Medicine, 2014
  • Brown-Séquard syndrome
    Indian Journal of Medical Research, 2014
  • Spontaneous emphysematous osteomyelitis of spine detected by computed tomography: Report of two cases
    SenthilKumar Aiyappan, Upasana Ranga, Saveetha Veeraiyan
    Journal of Craniovertebral Junction and Spine, 2014
  • Doppler sonography and 3D CT angiography of acquired uterine arteriovenous malformations: Report of two cases
    Senthil Kumar Aiyappan
    Journal of Clinical and Diagnostic Research, 2014
  • Unusual cause for abdominal pain in cirrhosis: Thrombosed intrahepatic portal vein aneurysms
    Senthil Kumar Aiyappan
    Journal of Clinical and Diagnostic Research, 2014
  • A case of intermittently discharging skin lesion: Orodentocutaneous fistula demonstrated on CT fistulography
    Senthil Kumar Aiyappan
    Journal of Clinical and Diagnostic Research, 2014
  • Acute mesenteric ischemia with intrasplenic gas: A rare occurrence
    Senthil Kumar Aiyappan
    Journal of Clinical and Diagnostic Research, 2014
  • An unusual case of hemoptysis
    SenthilKumar Aiyappan, Upasana Ranga, Saveetha Veeraiyan
    Lung India, 2014
  • A rare variant of Wallenberg's syndrome: Opalski syndrome
    Kannan R
    Journal of Clinical and Diagnostic Research, 2014
  • A case of chronic abdominal pain
    R. Kannan
    Journal of Clinical and Diagnostic Research, 2013
  • Anomalous origin of right pulmonary artery from aorta
    Senthil Kumar Aiyappan, Upasana Ranga, Saveetha Veeraiyan
    Indian Journal of Thoracic and Cardiovascular Surgery, 2013
  • Aneurysm of external jugular vein mimicking hemangioma of neck
    Senthil Kumar Aiyappan, Upasana Ranga, Saveetha Veeraiyan
    Indian Journal of Surgery, 2013
  • Anomalous origin of left coronary artery in an adult
    Indian Journal of Medical Research, 2013
  • A Case of Fecaloma
    Senthil Kumar Aiyappan, Upasana Ranga, Anita Samraj, Seena C. Rajan, Saveetha Veeraiyan
    Indian Journal of Surgery, 2013
  • Incidentally detected isolated unilateral pulmonary artery agenesis
    Senthil Kumar Aiyappan
    Journal of Clinical and Diagnostic Research, 2013
  • Ochronotic spondyloarthropathy
    Upasana Ranga
    Journal of Clinical and Diagnostic Research, 2013
  • Computed tomography fistulography demonstrating thyroglossal fistula: A case report
    Upasana Ranga, Senthil Kumar Aiyappan, Saveetha Veeraiyan
    Oral Surgery Oral Medicine Oral Pathology and Oral Radiology, 2012
  • Mycetoma of foot: MR imaging demonstrated the "dot-in-circle" sign
    Journal of Clinical and Diagnostic Research, 2012
  • Patulous internal auditory canals: A normal variant
    Journal of Clinical and Diagnostic Research, 2012
  • Comparison of neutral and positive enteral contrast media for MDCT enteroclysis
    Senthil Kumar Aiyappan, Naveen Kalra, Manavjit Singh Sandhu, Rakesh Kochhar, Jai Dev Wig, Niranjan Khandelwal
    European Journal of Radiology, 2012
  • Diabetic patient with involuntary movements
    Journal of Clinical and Diagnostic Research, 2011
  • Colitis and colonic perforation in a patient with breast carcinoma treated with taxane based chemotherapy
    KS Sodhi, SK Aiyappan, G Singh, M Prakash, N Khandelwal
    Indian Journal of Cancer, 2011
  • Duodenojejunal intussusception in Peutz-Jeghers syndrome: Report of a case
    Senthil Kumar Aiyappan, Mandeep Kang, Thakur Deen Yadav, Bishan Das Radotra, Niranjan Khandelwal
    Surgery Today, 2010
  • Solitary skeletal metastasis in carcinoma gallbladder: Two case reports
    Mahesh Prakash, Senthil Kumar Aiyappan, Ajay Kumar, Radhika Sreenivasan, T.D. Yadav, Niranjan Khandelwal
    Cancer Imaging, 2010
  • Utility of multidetector CT and virtual bronchoscopy in tracheobronchial obstruction in children
    Kushaljit Singh Sodhi, Senthil Kumar Aiyappan, Akshay Kumar Saxena, Meenu Singh, KLN Rao, Niranjan Khandelwal
    Acta Paediatrica International Journal of Paediatrics, 2010
  • Isolated unilateral aplasia of submandibular gland: A rare anomaly detected incidentally on computerized tomography
    Senthil Kumar Aiyappan, Upasana Ranga, Saveetha Veeraiyan
    Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology, 2010
  • Image-guided percutaneous drainage of an emphysematous bulla with a fluid level
    Naveen Kalra, Senthil Kumar Aiyappan, Surinder K Jindal, Niranjan Khandelwal
    Indian Journal of Radiology and Imaging, 2010
  • Anomaly of iliac veins: A rare cause of transient hepatic attenuation difference in a child
    Akshay Kumar Saxena, Senthil Kumar Aiyappan, Naveen Kalra, Alka Rani Khadwal, Kushaljit Singh Sodhi
    Pediatric Radiology, 2009
  • Metastatic carcinoma of cervix mimicking psoas abscess on imaging: A case report
    Naveen Kalra, Senthilkumar Aiyappan, Raje Nijhawan, S.C. Sharma, Niranjan Khandelwal
    Journal of Gynecologic Oncology, 2009
  • Unilateral multifocal mesenchymal hamartoma of the chest wall: a case report and review of literature
    Kushaljit Singh Sodhi, Senthil Kumar Aiyappan, Prema Menon, Pranab Dey, Niranjan Khandelwal
    Journal of Pediatric Surgery, 2009

RECENT SCHOLAR PUBLICATIONS

  • Organ-Specific CT Radiomics Signatures of Hepatic, Pancreatic, and Renal Parenchyma for Stratification of Glycaemic Status
    S Aiyappan
    2026
  • Severity Assessment of Acute Pancreatitis Using the Modified Computed Tomography Severity Index and Revised Atlanta Classification: Correlation with Bedside Index for Severity …
    MS Padma, K Bandari, YR Narayanan, SK Aiyappan
    Nigerian Postgraduate Medical Journal 33 (1), 111-117 , 2026
    2026
    Citations: 1
  • Diagnostic Utility of Apparent Diffusion Coefficient Values of Spleen and Liver in Assessment of Severity of Portal Hypertension and Liver Cirrhosis
    K Siddhardha, S Jalaludheen, SK Aiyappan
    Nigerian Postgraduate Medical Journal 33 (1), 118-124 , 2026
    2026
  • Imaging Findings of Ovarian Dermoid Cyst with Concurrent Torsion and Rupture.
    MS Pachipala, J Nehra, SS RAMESH, SK Aiyappan
    Journal of Clinical & Diagnostic Research 20 (1) , 2026
    2026
  • Solitary Long Bone Metastasis in Patients with Breast Cancer: Imaging Findings.
    AS RAnjAn, MAS APARnA, S ADDAGARLA, SK AIYAPPAN, S JEYARAJ
    Journal of Clinical & Diagnostic Research 20 (1) , 2026
    2026
  • Genitourinary Tuberculosis with Co-existing Transitional Cell Carcinoma of the Urinary Bladder: Imaging Findings and Diagnostic Challenges.
    V REDDY, YRAA RAo, SK AIYAPPAN
    Journal of Clinical & Diagnostic Research 19 (12) , 2025
    2025
  • Imaging findings in Klippel-feil Syndrome with Unilateral Renal Agenesis and Ectopic Pelvic Kidney.
    J NEHRA, MS PACHIPALA, SK AIYAPPAN, SS RAMESH, ...
    Journal of Clinical & Diagnostic Research 19 (12) , 2025
    2025
  • Post Contrast-Acute Kidney Injury in CT Imaging: A Knowledge, Perception and Practice Assessment among Radiographers and Radiologists
    P Pavadai, VR Lazar, K Sathyakumar, SK Aiyappan, P Baskar, ...
    Giornale italiano di nefrologia: organo ufficiale della Societa italiana di … , 2025
    2025
  • Supratenorial Haemangioblastoma with Bleed: Imaging Findings.
    JSP JOSEPH, P SuSHmA, SK AIYAPPAN
    Journal of Clinical & Diagnostic Research 19 (7) , 2025
    2025
  • Multimodal MRI and PET/SPECT Brain Image Integration for improved clinical diagnosis of PACS in Health care.
    S Vijayan, M Subramani, SK Aiyappan
    KSII Transactions on Internet & Information Systems 19 (7) , 2025
    2025
  • Follicular Carcinoma of Thyroid with Solitary Vertebral Metastasis.
    J NEHRA, SI MUSTAFA, K SATHYAKUMAR, SK AIYAPPAN
    Journal of Clinical & Diagnostic Research 19 (6) , 2025
    2025
  • Imaging Findings of Pituitary Stalk Interruption Syndrome.
    YR RAO, SK AIYAPPAN, JSP JOSEPH, RSAI DACHEPALLI
    Journal of Clinical & Diagnostic Research 19 (5) , 2025
    2025
  • Uterine and Ovarian Stromal Blood Flow in Patients with Polycystic Ovarian Syndrome and Healthy Women by Doppler Ultrasonography: A Comparative Study
    R Rajagopal, S Aiyappan, R Ramesh, D Arunkumar, J Murugan
    Asian Journal of Pharmaceutical Research and Health Care 17 (2), 189-195 , 2025
    2025
  • Stanford Type A Acute Aortic Dissection with Left Coronary Artery Involvement: Computed Tomography Angiography Findings.
    NN KUMAR, R RAJAGOPAL, D ARUNKUMAR, SK AIYAPPAN, ...
    Journal of Clinical & Diagnostic Research 19 (3) , 2025
    2025
  • Beyond the Surface: Delving Deeper Into Leukoaraiosis With Multivoxel Magnetic Resonance Spectroscopy
    Р Рагита, С Арунан, А Сентилкумар, Р Сабари
    Инновационная медицина Кубани, 27-33 , 2025
    2025
  • Renal Angiomyolipoma with Rupture Causing Perinephric Hematoma
    NN Kumar, SK Aiyappan, AM Shobana, S Addagarla
    Asian Journal of Pharmaceutical Research and Health Care 17 (1), 94-96 , 2025
    2025
  • Imaging Findings of Ovarian Adenofibroma in Multiparous Woman.
    S JEYARAJ, JSP JOSEPH, A RANJAN, SK AIYAPPAN
    Journal of Clinical & Diagnostic Research 19 (1) , 2025
    2025
  • Imaging findings of Neonatal Mastitis
    YR RAO, DA KUMAR, L PRABAKARAN, SK AIYAPPAN, A RANJAN
    INDIAN JOURNAL OF NEONATAL MEDICINE AND RESEARCH Учредители: JCDR Research … , 2025
    2025
  • Human Parechovirus Encephalitis in a Neonate: Neuroimaging Findings.
    JS PRAVEENA JOSEPH, P SUSHMA, A RANJAN, SK AIYAPPAN
    Journal of Clinical & Diagnostic Research 18 (12) , 2024
    2024
  • Diagnostic Accuracy of Diffusion Weighted Imaging in Differentiating Benign and Malignant Breast Lesions: A Cross-Sectional Study
    S Khan, SK Aiyappan, R Ramesh, S Natarajan, RS Dachepalli
    ANNALS OF ABBASI SHAHEED HOSPITAL AND KARACHI MEDICAL & DENTAL COLLEGE 29 (4 … , 2024
    2024

MOST CITED SCHOLAR PUBLICATIONS

  • Utility of multidetector CT and virtual bronchoscopy in tracheobronchial obstruction in children
    KS Sodhi, SK Aiyappan, AK Saxena, M Singh, KLN Rao, N Khandelwal
    Acta Paediatrica 99 (7), 1011-1015 , 2010
    2010
    Citations: 55
  • Doppler sonography and 3D CT angiography of acquired uterine arteriovenous malformations (AVMs): report of two cases
    SK Aiyappan, U Ranga, S Veeraiyan
    Journal of clinical and diagnostic research: JCDR 8 (2), 187 , 2014
    2014
    Citations: 51
  • Role of gray scale, color Doppler and spectral Doppler in differentiation between malignant and benign thyroid nodules
    MK Palaniappan, SK Aiyappan, U Ranga
    Journal of clinical and diagnostic research: JCDR 10 (8), TC01 , 2016
    2016
    Citations: 42
  • A rare variant of Wallenberg’s syndrome: Opalski syndrome
    KK Parathan, R Kannan, P Chitrambalam, N Deepthi
    Journal of Clinical and Diagnostic Research: JCDR 8 (7), MD05 , 2014
    2014
    Citations: 36
  • Spontaneous emphysematous osteomyelitis of spine detected by computed tomography: Report of two cases
    SK Aiyappan, U Ranga, S Veeraiyan
    Journal of Craniovertebral Junction and Spine 5 (2), 90-92 , 2014
    2014
    Citations: 28
  • Unilateral multifocal mesenchymal hamartoma of the chest wall: a case report and review of literature
    KS Sodhi, SK Aiyappan, P Menon, P Dey, N Khandelwal
    Journal of pediatric surgery 44 (2), 464-467 , 2009
    2009
    Citations: 25
  • Metastatic carcinoma of cervix mimicking psoas abscess on imaging: a case report
    N Kalra, S Aiyappan, R Nijhawan, SC Sharma, N Khandelwal
    Journal of Gynecologic Oncology 20 (2), 129-131 , 2009
    2009
    Citations: 18
  • A case of fecaloma
    SK Aiyappan, U Ranga, A Samraj, SC Rajan, S Veeraiyan
    Indian Journal of Surgery 75 (4), 323-324 , 2013
    2013
    Citations: 17
  • Solitary skeletal metastasis in carcinoma gallbladder: Two case reports
    M Prakash, SK Aiyappan, A Kumar, R Sreenivasan, TD Yadav, ...
    Cancer Imaging 10 (1), 121 , 2010
    2010
    Citations: 15
  • Comparison of neutral and positive enteral contrast media for MDCT enteroclysis
    SK Aiyappan, N Kalra, MS Sandhu, R Kochhar, JD Wig, N Khandelwal
    European Journal of Radiology 81 (3), 406-410 , 2012
    2012
    Citations: 14
  • Idiopathic subareolar breast abscess in a male patient
    SK Aiyappan, U Ranga, S Veeraiyan
    Journal of Clinical and Diagnostic Research: JCDR 9 (1), TJ01 , 2015
    2015
    Citations: 13
  • Isolated unilateral aplasia of submandibular gland: a rare anomaly detected incidentally on computerized tomography
    SK Aiyappan, U Ranga, S Veeraiyan
    Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and … , 2010
    2010
    Citations: 13
  • Age-related normogram for ovarian antral follicle count in women with polycystic ovary syndrome and comparison with age matched controls using magnetic resonance imaging
    SK Aiyappan, B Karpagam, V Vadanika, PK Chidambaram, S Vinayagam, ...
    Journal of Clinical and Diagnostic Research: JCDR 10 (1), TC11 , 2016
    2016
    Citations: 11
  • Colitis and colonic perforation in a patient with breast carcinoma treated with taxane based chemotherapy
    KS Sodhi, SK Aiyappan, G Singh, M Prakash, N Khandelwal
    Indian Journal of Cancer 48 (1), 134-135 , 2011
    2011
    Citations: 11
  • Aneurysm of external jugular vein mimicking hemangioma of neck
    SK Aiyappan, U Ranga, S Veeraiyan
    Indian Journal of Surgery 75 (6), 493-495 , 2013
    2013
    Citations: 10
  • Computed tomography fistulography demonstrating thyroglossal fistula: a case report
    U Ranga, SK Aiyappan, S Veeraiyan
    Oral surgery, oral medicine, oral pathology and oral radiology 114 (3), e48-e50 , 2012
    2012
    Citations: 10
  • Correlation of placental thickness with gestational age in second and third trimester using ultrasonography
    KN Vinchurkar, SK Aiyappan, C Prem Kumar, V Shanmugam, A Singh
    Egyptian Journal of Radiology and Nuclear Medicine 54 (1), 164 , 2023
    2023
    Citations: 9
  • A case of intermittently discharging skin lesion: Orodentocutaneous fistula demonstrated on CT fistulography
    U Ranga, SK Aiyappan, S Veeraiyan
    Journal of Clinical and Diagnostic Research: JCDR 8 (8), ZD09 , 2014
    2014
    Citations: 8
  • Omental infarct mimicking acute pancreatitis
    SK Aiyappan, U Ranga, S Veeraiyan
    Indian Journal of Surgery 77 (Suppl 3), 1393-1394 , 2015
    2015
    Citations: 7
  • Double fistula: Bronchopleural and pleurocutaneous
    SK Aiyappan, U Ranga, S Veeraiyan
    Lung India 32 (1), 88-89 , 2015
    2015
    Citations: 7