DARSI ESWAR TONY

@chalapathipharmacy.in

Professor - Pharmacology
Chalapathi Institute of Pharmaceutical Sciences

DARSI ESWAR TONY


                     Download Compact PDF  
https://researchid.co/eswartony
13

Scopus Publications

518

Scholar Citations

7

Scholar h-index

5

Scholar i10-index

Scopus Publications

  • ACCESS, AFFORDABILITY AND BIOPIRACY: ETHICAL FRONTIERS IN GLOBAL PHARMACOLOGY
    Pharma Times, 2025
  • MICROBIOME-TARGETED THERAPIES: REVOLUTIONIZING PRECISION MEDICINE AND DRUG DEVELOPMENT
    Pharma Times, 2025
  • PHARMACOLOGICAL EVALUATION OF STRESS INDUCED INSOMNIA IN MICE THROUGH BRIGHTNESS DISCRIMINATION TO PROLONG SLEEP ONSET LATENCY
    Journal of Experimental Zoology India, 2025
  • A PRECLINICAL APPROACH ON MEMORY IMPAIRMENT IN MICE WITH SCOPOLAMINE INDUCED AMNESIA USING AUTOMATED MOTION TRACKING IN MORRIS WATER MAZE
    Journal of Experimental Zoology India, 2025
  • ASSESSMENT OF SLEEP CYCLE AND SLEEP INDUCED DISORDERS IN RELATION WITH ACADEMIC PERFORMANCE
    Journal of Experimental Zoology India, 2025
  • PHARMACEUTICAL ENTREPRENEURSHIP: CREATING OPPORTUNITIES FOR PHARMACY GRADUATES
    Pharma Times, 2024
  • Molecular docking studies, analgesic and anti-inflammatory screening of some novel quinazolin-4-one derivatives
    K.N. Rajini Kanth, Ch. Jaswanth Kumar, D. Eswar Tony, Sk. Munwar, Rama Rao Nadendla, Chandragiri Siva Sai
    Asian Journal of Chemistry, 2021
    Molecular docking studies was performed on 20 analogous novel quinazolin-4-one derivatives as cox-2 inhibitors using glide tool of maestro 11.4 application of Schrodinger software. Anti-inflammatory and analgesic activities were further evaluated for the compounds. Based on docking studies, the binding affinity of QZN-16 was found to be -10.32 kcal/mol. In order to understand the significance of R-substituents on the quinazoline-4-one nucleus, the findings of hydrogen bonding interactions between designated ligands with binding site region of 4cox were studied. The ligands which are having high docking score were subjected to pharmacological screening. The compound QZN-16 has shown analgesic and anti-inflammatory activity at a dose level of 50 and 100 mg/kg body weight, respectively when compared with standard drug indomethacin. The newly designed quinazoline-4-one derivatives may serve as lead molecules for further development.
  • Synergistic effect of leaf extracts of ficus hispida and psidium Guajava for anti-diabetic activity on wistar rats
    M. Mounica, G. Tanuja Lakshmi, K. Manaswini, D. Eswar Tony, A. Narendra Babu
    Research Journal of Pharmacy and Technology, 2020
    Ficus hispida (tropical fig tree) is a moderate sized tree which is commonly known as devil fig, traditionally used in the ailment of pain, inflammation, and neurological disorders. Psidium guajava (Guava/peru)is a wellknown tropical tree and also used as a folk herbal tea used to treat diabetes and leaves were used as astringent, anodyne, febrifuge, antispasmodic, tonic, in wounds, cholera, lactagouge, diarrhoea, vomiting and variety of diseases like diarrhoea, dysentery, hypertension, gastroenteritis, diabetes, cough, oral ulcers etc., The aim of the present study is set out to evaluate the anti-diabetic activity of ethanolic leaf extracts of ficus hispida and psidium guajava on streptozocin induced diabetized rats. The leaf extracts at a dose of 100mg/kg were screened for their blood glucose lowering effectamong streptozocin induced diabetized rats and the blood samples were collected through the tail vein from which blood glucose levels were determinedat 0h, 1h, 2h and 4hafter administration of test samples. Both the leaf extracts of Ficus hispida and Psidium guajava produced significant (p 0.01) decrease in the blood glucose levels. The ethanolic extract of leaves of Ficus hispida and Psidium guava produced synergistic effect when compared with standard by showing an effective response on diabetic rats. These plants supported the folk fore claim of anti-diabetic activity. Further investigations are needed for the proper identification and isolation of these bioactive compounds to produce safer drugs for treatment of harmful diseases.
  • Pharmacological evaluation of leaf extract of Terminalia bellerica with Moringa oleifera for its synergistic action on anti-diabetic activity and anti-inflammatory activity in rats
    Sk. Karishma, K. Lakshmi, D. Eswar Tony, A. Narendra Babu, Rama Rao Nadendla
    Research Journal of Pharmacy and Technology, 2019
    Aim and Objective: To evaluate the pharmacological action of leaf extract of Terminalia bellerica with Moringa oleifera for its synergistic action on Anti Diabetic activity and Anti-inflammatory activity in rats. Methodology: The Pharmacological evaluation of standardized aqueous extract of the leaves of Terminalia bellerica with Moringa oleifera was carried by using the following Stimuli models: a)Antidiabetic activity by Streptozotocin Induced Diabetes, b) Anti-inflammatory activity by Egg Albumin Induced Paw Edema. Results: The parameters of various activities to assess anti diabetic and anti inflammatory activities were evaluated and found That, The combination of extracts possess a better response then alone. Conclusion: The aqueous leaf extract of the combination of Terminalia bellerica with Moringa oleifera has shown significant anti diabetic and anti-inflammatory activities when compared with standard and extract alone.
  • Pharmacological evaluation of leaf extracts of crataeva religiosa for its anxiolytic activity in albino mice
    Journal of Pharmaceutical Sciences and Research, 2018
  • Effect of tragia plukenetii r-smith leaf extracts on learning, memory and reasoning using hebbs william maze
    Research Journal of Pharmaceutical Biological and Chemical Sciences, 2013
  • Etiopathogenesis and clinical management of inflammatory bowel disease
    Research Journal of Pharmaceutical Biological and Chemical Sciences, 2013
  • Aceclofenac floating tablets - A promising sustained release dosage form
    International Journal of Drug Development and Research, 2011

RECENT SCHOLAR PUBLICATIONS

  • A study on Fourier transform infrared (FTIR) spectroscopy for polygalacturonase production by four fungal strains from mangrove soils Krishna district, Andhra Pradesh.
    R Ketipally, DE Tony, PV Suresh
    Journal of Applied & Natural Science 17 (4) , 2025
    2025
  • A Modified Elevated Circular Maze Model for Rapid Detection of Anxiolytic Effects of Rhynchosia minima Extract in Rodents
    G Sashiman, KH Varshini, KN Mani, G Hema, DE Tony, DR Babu, ...
    UTTAR PRADESH JOURNAL OF ZOOLOGY 46 (20), 70-77 , 2025
    2025
  • Design and Preclinical Evaluation of a Novel Anxiety Chamber for Assessing Aromatherapy-Mediated Anxiolytic Effects in Rodents
    DE Tony, CN Vyshnavi, P Roshini, MS Harika, SJSN Sandhya, ...
    UTTAR PRADESH JOURNAL OF ZOOLOGY 46 (18), 321-328 , 2025
    2025
  • Weakly Electric Fish as Emerging Models for Neuroprotection and CNS Drug Discovery
    D Snehalatha, K Prabhath, YR Sri, P Byram, DE Tony, DR Babu
    UTTAR PRADESH JOURNAL OF ZOOLOGY 46 (17), 110-117 , 2025
    2025
  • Illuminating the Future: Danio Rerio as Game Changing Model for Vision Restoration
    G Sashiman, SL Pujitha, B Gurulakshmi, DV Rani, DE Tony, ...
    UTTAR PRADESH JOURNAL OF ZOOLOGY 46 (10), 167-172 , 2025
    2025
  • Microbiome Targeted therapies: Revolutionizing Precision medicine and Drug Development
    RRN D Eswar Tony, D Rajesh Babu, Sk Musharaff, Ravi ketipally
    Pharma Times 57 (4), 19-20 , 2025
    2025
  • Assessment of anti-hyperlipidemic potential of Ocimum sanctum and Trachyspermum ammi in high fat diet induced hyperlipidemia
    DRBRRN D. Eswar Tony, Sk. Musharaff, A. Abhiram Reddy, K. Guru Maheswara ...
    Biochemical and Cellular Archives 25 (1), 929-935 , 2025
    2025
  • Pharmacological Evaluation of Anti-anxiety Effect of Polyherbal Powders on Mice Through Locomotion and Behavioral Studies Using Brightness Discrimination
    P Rachana, M Mounika, M Bhavana, M Priyanka, DE Tony, DR Babu
    UTTAR PRADESH JOURNAL OF ZOOLOGY 46 (9), 1-8 , 2025
    2025
  • Development and Efficacy Assessment of a Natural Anti-inflammatory Cream: An In vivo Study on Carrageenan-induced Paw Edema in Rats
    TD Eswar, M Preethika, SK Meenakshi, R Niharika
    Uttar Pradesh Journal of Zoology , 2025
    2025
    Citations: 1
  • Neuropharmacological Evaluation of Ocimum sanctum and Coleus amboinicus in Experimental Model of Depression
    DE Tony, KS Krishna, N Ramarao
    UTTAR PRADESH JOURNAL OF ZOOLOGY 46 (5), 73-86 , 2025
    2025
  • A PRECLINICAL APPROACH ON MEMORY IMPAIRMENT IN MICE WITH SCOPOLAMINE INDUCED AMNESIA USING AUTOMATED MOTION TRACKING IN MORRIS WATER MAZE.
    DE Tony, M Vasavi, M Jahnavi, M Sai Keerthana, KS Chowdary, ...
    Journal of Experimental Zoology India 28 (1) , 2025
    2025
  • PHARMACOLOGICAL EVALUATION OF STRESS INDUCED INSOMNIA IN MICE THROUGH BRIGHTNESS DISCRIMINATION TO PROLONG SLEEP ONSET LATENCY.
    DE Tony, JV Krishna, DR Babu, RR Nadendla
    Journal of Experimental Zoology India 28 (1) , 2025
    2025
  • ASSESSMENT OF SLEEP CYCLE AND SLEEP INDUCED DISORDERS IN RELATION WITH ACADEMIC PERFORMANCE.
    S Musharaff, MA Reddy, YP Anu, MG Shankar, DE Tony, RR Nadendla
    Journal of Experimental Zoology India 28 (1) , 2025
    2025
  • Formulation of Mosquito Repellant Freshener Gel with China Grass as Gel Base and Lemon Grass Oil as Mosquito-Repellant
    B Reddy, DE Tony, RR Nadendla
    UTTAR PRADESH JOURNAL OF ZOOLOGY 45 (22), 141-148 , 2024
    2024
  • Muscle Strength Maze, Equipment to assess the physical activity of Rodents in Diet induced Hyperlipidemia
    RRN D Eswar Tony
    IN Patent 518,065 , 2024
    2024
  • UNLOCKING WHEEZING'S TALE: A SYSTEMATIC OBSERVATIONAL STUDY ON INSIGHTS OF ASTHMA AND IT'S MANAGEMENT
    BRSBR Shaik, HSH Syed, VMPRV Madhu, P Reddy, DETDE Tony
    World Wide Journals 12 (8) , 2023
    2023
  • A Comparative Research between Pharmacological and Non-Pharmacological Profile of Anti-Hyperlipidemic Activity on Rodents
    DE Tony, MU Kiran, MA Saleha, RS Naik, UB Sai, V Niranjan, T Kowshik, ...
    Journal of Drug Delivery & Therapeutics 11 (5), 65-70 , 2021
    2021
  • Review on resealed erythrocytes
    NS Prameel, DE Tony, AN Babu, R Naveen, B Padmavathi, K Kiranmai
    Journal of Drug Delivery & Therapeutics 11 (5), 65-70 , 2021
    2021
    Citations: 1
  • Molecular Docking Studies, Analgesic and Anti-inflammatory Screening of Some Novel Quinazolin-4-one Derivatives
    CSS K.N.Rajini Kanth, Ch.Jaswanth Kumar, D. Eswar Tony, Sk. Munwar, Rama Rao ...
    Asian Journal of Chemistry 33 (5), 1058-1062 , 2021
    2021
    Citations: 2
  • Synergistic Effect of Leaf Extracts of Ficus hispida and Psidium guajava for Anti-Diabetic Activity on Wistar Rats
    M Mounica, GT Lakshmi, K Manaswini, DE Tony, AN Babu
    Research Journal of Pharmacy and Technology 13 (6), 2877-2880 , 2020
    2020
    Citations: 2

MOST CITED SCHOLAR PUBLICATIONS

  • A review on: Abelmoschus esculentus (Okra)
    DS Kumar, DE Tony, AP Kumar, KA Kumar, DBS Rao, R Nadendla
    International Research Journal of Pharmaceutical and Applied Sciences 3 (4 … , 2013
    2013.0
    Citations: 404
  • Aceclofenac floating tablets-a promising sustained release dosage form
    NS Kumar
    Int J Drug Dev & Res 3 (2), 290-300 , 2011
    2011.0
    Citations: 24
  • Kumar a P., Kumar KA, Rao DBS and Nadendla R. 2013" A Review on: Abelmoschus Esculentus (Okra),"
    DS Kumar, DE Tony
    Int. Res. J. Pharm. appied Sci 3, 129-132 , 0
    Citations: 18
  • Pharmacological evaluation of leaf extract of Terminalia bellerica with Moringa oleifera for its synergistic action on anti-diabetic activity and anti-inflammatory activity in rats
    S Karishma, K Lakshmi, DE Tony, AN Babu, RR Nadendla
    Research Journal of Pharmacy and Technology 12 (3), 1181-1184 , 2019
    2019.0
    Citations: 16
  • REV I EW
    V Kumar, S Gunner, M Pregnolato, P Tully, N Georgalas, G Oikonomou, ...
    2013.0
    Citations: 15
  • Chamaecostus cuspidatus-A short review on anti diabetic plant
    AN Jyothi, E Priyanka, DE Tony, RR Nadendla
    Indo American Journal of Pharmaceutical Sciences 2 (7), 1110-1113 , 2015
    2015.0
    Citations: 9
  • Assessment of in vitro anti inflammatory activity of aqueous extract of Ipomoea batatas tubers
    T Mercy Margaret, P Krishna, B Revathi, D Eswar Tony, M Sathish Kumar, ...
    Asian Journal of Research in Biological and Pharmaceutical Sciences 1 (1), 47-53 , 2013
    2013.0
    Citations: 9
  • Evaluation of nootropic activity of leaf extract of typha angustata
    DET K Ashok Kumar, M Sathish Kumar, A Narendra Babu
    International Journal of Preclinical and Pharmaceutical Research 5 (2), 57-60 , 2014
    2014.0
    Citations: 3
  • Typha angustata leaf extract ameliorates phenothiazine induced catatonia in wistar rats
    KA Kumar, MS Kumar, AN Babu, DE Tony
    IJBPR 5 (3), 290-292 , 2014
    2014.0
    Citations: 3
  • Molecular Docking Studies, Analgesic and Anti-inflammatory Screening of Some Novel Quinazolin-4-one Derivatives
    CSS K.N.Rajini Kanth, Ch.Jaswanth Kumar, D. Eswar Tony, Sk. Munwar, Rama Rao ...
    Asian Journal of Chemistry 33 (5), 1058-1062 , 2021
    2021.0
    Citations: 2
  • Synergistic Effect of Leaf Extracts of Ficus hispida and Psidium guajava for Anti-Diabetic Activity on Wistar Rats
    M Mounica, GT Lakshmi, K Manaswini, DE Tony, AN Babu
    Research Journal of Pharmacy and Technology 13 (6), 2877-2880 , 2020
    2020.0
    Citations: 2
  • Pharmacological evaluation of extract of Lannea coromandelica (Linn) for its anti-ulcer activity in rodents.
    NS Priya, MS Aruna, DE Tony, RR Nadendla
    2015.0
    Citations: 2
  • Pharmacological investigation of leaf extract of Typha angustata for depressant activity
    NVR Rao, GD Sri, M Dastagiri
    Asian Journal of Pharmacology and Toxicology 2 (03), 01-03 , 2014
    2014.0
    Citations: 2
  • Evaluation of Memory enhancement activity and shock motivated brightness discrimination response using Y-Maze
    NRR D Eswar Tony. T Vijaya, D Sathish Kumar, M Sathish Kumar, A Narendra babu
    Research Journal of Pharmaceutical, Biological and Chemical Sciences 4 (4 … , 2013
    2013.0
    Citations: 2
  • Ramarao Nadendla Chalapathi institute of pharmaceutical sciences, Guntur, Andhra Pradesh, India
    DS Kumar, DE Tony, AP Kumar, KA Kumar, DBS Rao
    International Research Journal of Pharmaceutical and Applied Sciences … , 2013
    2013.0
    Citations: 2
  • Development and Efficacy Assessment of a Natural Anti-inflammatory Cream: An In vivo Study on Carrageenan-induced Paw Edema in Rats
    TD Eswar, M Preethika, SK Meenakshi, R Niharika
    Uttar Pradesh Journal of Zoology , 2025
    2025.0
    Citations: 1
  • Review on resealed erythrocytes
    NS Prameel, DE Tony, AN Babu, R Naveen, B Padmavathi, K Kiranmai
    Journal of Drug Delivery & Therapeutics 11 (5), 65-70 , 2021
    2021.0
    Citations: 1
  • Evaluation of Anti-Catatonic Effect of Stem Extracts of Securinega leucopyrus on Haloperidol Induced Catatonia in Rats
    GC Sekhar, JG Chand, SA Sultana, K Lakshmi, DE Tony, AN Babu, ...
    Int. J. Pharm. Biol. Sci 9, 337-341 , 2019
    2019.0
    Citations: 1
  • Pharmacological evaluation of leaf extracts of Crataeva religiosa for its anxiolytic activity in Albino mice
    NR Lakshmi, P Hemasoundarya, BG Rao, DE Tony, N Ramarao
    Journal of Pharmaceutical Sciences and Research 10 (2), 431-433 , 2018
    2018.0
    Citations: 1
  • Pharmacological evaluation of Citharexylum serratum for its anxiolytic and muscle relaxant activities on mice.
    TVP Kotapati, KHSTS Ram, JV Yadav, GM Rao, KS Srikar, K Giridhar, ...
    2018.0
    Citations: 1