Gaetano Burriesci

Scopus Publications

In silico analysis of the haemodynamic disturbances caused by the subaortic membrane pathology
Alessandra Monteleone, Gaetano Burriesci
Computers in Biology and Medicine, 2026
Subaortic stenosis, a heart disease characterised by a narrowing of the left ventricular outflow tract, is frequently caused by the presence of a subaortic membrane (SAM) located at the aortic valve inlet. This anatomical obstruction leads to significant haemodynamic alterations and leaflets fluttering, whose mechanisms are not yet fully understood. This research investigates, through computer simulations, the SAM's haemodynamic impact and the mechanism behind leaflets fluttering. A mono-physics fluid-structure interaction approach, based on the meshless smoothed particle hydrodynamics method, was employed. This approach represents both blood and structures with particles without defining interfaces, efficiently capturing large deformations and dynamic phenomena. Two common types of SAMs were investigated - a discrete thin SAM layer (flexible) and a thick fibromuscular ridge SAM (stiff) - and compared with a healthy aortic valve. Projected dynamic valve area (PDVA) was used as a reference parameter to quantify leaflet oscillation. While the PDVA in the healthy aortic valve stabilised at 283 mm 2 without oscillation, both pathological cases exhibited self-sustained periodic fluctuations. In the presence of discrete thin SAM layer, the mean PDVA decreased by 3% compared to the healthy control. This reduction was more pronounced for thick fibromuscular ridge configurations, where the mean PDVA was 9% lower than the healthy case. Notably, stiffer SAM configurations more than doubled the oscillation amplitude (from 3.12 mm 2 to 6.77 mm 2 ) and increased the oscillation frequency by 8% relative to flexible membranes. Vortices dynamics was analysed, determining the phases of their formation, growth and migration. Through the analysis of velocity, vorticity, and shear stress maps, this study provides critical insights into the origin of fluttering and its influence over these key haemodynamic parameters. Findings demonstrate that the oscillatory leaflet motion is the result of vortices formation and shedding. The stiffness of the SAM significantly modulates the fluttering behaviour. While structural damage and haematological complications were not directly simulated, the identified oscillations represent haemodynamic conditions associated in literature with such pathologies. The observed alterations in wall shear stress magnitude and direction provide a physical basis for the mechanical environment that could contribute to endothelial cell dysfunction in the presence of SAM. • Subaortic membrane (SAM) is one of the most common congenital heart defects. • SAM causes leaflet fluttering through a mechanism not yet understood. • A mono-physics fluid-structure interaction approach was used to study SAM disease. • The SAM's haemodynamic impact and the mechanism behind fluttering are investigated. • The potential implication of leaflet fluttering on endothelial injury is explored.
Critical analysis of strain measurement approaches in tensile testing of nitinol
Valentina Pinto, Sofia Di Leonardo, Giuseppe Pitarresi, Gaetano Burriesci
Proceedings of the Institution of Mechanical Engineers Part C Journal of Mechanical Engineering Science, 2026
Nitinol superelasticity is a crucial property for collapsible/expandable cardiovascular implants. The high class of risk associated with these devices requires an accurate mechanical characterisation as starting point for a reliable design methodology. Actual standards (ASTM-F2516) are based on standard metal testing and recommend the use of extensometers for the measurement of average nominal strains during tensile tests. However, measurement provided by classic extensometers may not be adequate to capture the strain evolution during the material phase transformation. These limitations can be overcome by full-field optical techniques such as Digital Image Correlation (DIC). This work presents a comprehensive comparison of various techniques for measuring strain on nitinol specimens. These include crosshead position, single and averaging (applied on both sides of the specimen) measurements using physical extensometers, virtual extensometer, and 1D and 2D DIC. Results are compared on the basis of the values determined for the upper/lower plateau stress, as defined by ASTM-F2516. Results show that the use of extensometers on nitinol strips subjected to tensile testing is inaccurate during phase transformation. Physical extensometers also introduce spurious local concentrated pressures at the knives contact region, which may alter the material stress plateaus values. DIC resulted more adequate to provide an accurate evaluation of strain localisation.
An advanced immersed fluid–structure interaction particle method for cardiovascular applications experimentally validated vs a new benchmark case
Alessandra Monteleone, Sofia Di Leonardo, Marco Correnti, Enrico Napoli, Giorgio Micale, Gaetano Burriesci
Physics of Fluids, 2026
Fluid–structure interaction (FSI) is crucial in the numerical simulation of cardiovascular phenomena, where pulsatile blood flow dynamically interacts with highly deformable tissues. High-fidelity FSI approaches have become essential to enhance the understanding of potentially lethal pathologies, assisting diagnosis and development of novel therapeutic solutions. This work presents and experimentally validates a new, totally meshless FSI approach, specifically designed for cardiovascular applications. The method is based on the Lagrangian smoothed particle hydrodynamics (SPH), employing a unified physics to represent both blood and deformable walls, avoiding FSI interfaces. A key advantage of this method lies in its ability to overcome the SPH complex issue in contour management, a common challenge that typically increases the complexity of this methodology in FSI applications. Deformable walls are immersed in the fluid domain, and a buffer region of fluid is defined to handle the structural deformation. For validation, a new FSI benchmark is proposed and analyzed with the particle image velocimetry technique. Tailored to entail the typical complexities of relevant cardiovascular situations, the benchmark involves pulsatile flow interacting with a chamber with deformable curved walls, moving through both filling and emptying phases. Despite its simplified geometry, designed to allow a reliable experimental validation, the structure experiences a field of three-dimensional strains and large volume variations, thereby replicating complexities often associated with more intricate models. Numerical and experimental results show good agreement in terms of fluid velocity field and structural deformation, establishing the proposed totally meshless FSI approach as a reliable tool for complex cardiovascular modeling.
Artificial Muscles for Footwear Technology: Knitting Structures With Variable Elasticity
Felipe Sheward, Gaetano Burriesci, Daniela M. Romano
Advances in Materials Science and Engineering, 2026
Current commercial midsoles provide a fixed level of cushioning and elasticity regardless of gait phase or loading rate. We report a novel “artificial muscle” midsole composite that dynamically tunes its compressive stiffness and relaxation behavior by embedding nickel–titanium (Nitinol) shape‐memory alloy (SMA) wires into multilayer silicone substrates (Shore A12, A20, A30) using two hand‐knitting patterns (A and C). Specimens (undeformed height = 30 mm; frontal area = 61,213.856 mm 2 or 612.139 cm 2 ) were tested on a 50 kN Instron 5969 under displacement control. For compression (stress–strain) testing, each sample was ramped from an initial grip separation of 30 mm to a 12.5 mm gap (≈58.33% nominal compressive strain) at 200 mm/min (≈0.111 s −1 strain rate). At each voltage state (0 V ⟶ 14 V for Pattern A; 0 V ⟶ 10 V for Pattern C), four loading–unloading cycles were conducted at 60 mm/min (≈0.033 s −1 strain rate). For stress‐relaxation (creep) testing, specimens were ramped from 30 mm to a 12.5 mm gap (≈58.33% strain) at 60 mm/min (≈0.033 s −1 ) and then held at constant displacement for 120 s under three voltage levels (Pattern A: 0 V, 14 V, 19 V; Pattern C: 0 V, 8 V, 14 V). Under these protocols, silicone A30 with Pattern C consistently exhibited the largest actuation‐induced contraction (Δ = 27.79% in compression; Δ = 36.54% in creep/relax), while MANOVA and t ‐test results confirmed that substrate hardness, actuation state, and knitting pattern each significantly modulated compressive stress (all p < 0.001). These findings demonstrate that our SMA‐enabled midsole can switch between soft and stiff modes—across ≈58.3% strain at strain rates up to ≈0.111 s −1 —offering a tunable, durable, and cost‐effective solution for adaptive footwear.
An Innovative One-Step Method to Produce Membranes with a Pore Size Gradient
Inzerillo E., Brucato V., Burriesci G., Carfi Pavia Francesco, Ingrassia T.
Chemical Engineering Transactions, 2026
The fabrication of porous scaffolds with continuous pore size gradients is growing in interest in tissue engineering, as graded architectures better mimic the structural heterogeneity of native interfacial tissues. Conventional strategies based on monolayer scaffolds fail to reproduce this heterogeneity, while multilayer constructs introduce interfaces that do not ensure continuous transitions in structural and mechanical properties. Although most gradient fabrication approaches rely on multistep or post-processing techniques, limited attention has been focused to procedures allowing to obtain directly the final scaffold. Thermally induced phase separation is a versatile method for regulating pore morphology in scaffold by controlling the thermal history. This work investigates a TIPS-based strategy to generate continuous pore size gradients by tailoring heat transfer directionality. Poly-L-lactic acid scaffolds were produced using two process configurations differing in the presence or absence of thermal insulation and analysed using a combined experimental and numerical approach. Scaffold morphology was characterised by scanning electron microscopy, while thermal transient simulations were performed to investigate temperature evolution during phase separation and freezing. The analysis highlights differences in cooling behaviour between the two configurations, correlating these with variations in pore size distribution across the scaffold thickness. The results demonstrated that it is possible to obtain scaffold with a pore size gradient through a one-step TIPS procedure.
The use of human decellularized amniotic membrane as pulmonary valve leaflets in right ventricular outflow tract reconstruction – an in vivo proof of concept study
Mohamed T. Ghorbel, Tasneem Salih, Giulia Parolari, Katie L. Skeffington, Sofia Di Leonardo, Danila Vella, Gaetano Burriesci, Massimo Caputo, Dominga Iacobazzi
Frontiers in Bioengineering and Biotechnology, 2026
Introduction Despite fundamental improvements in surgical treatment of Congenital Heart Defects, there are still challenges related to premature failure of the material used for such corrections, thus resulting in repeated operations during a patient’s life. This is particularly the case for complex defects with Right Ventricular Outflow Tract (RVOT) obstruction, such as in Tetralogy of Fallot/Pulmonary Atresia, whereby the pulmonary valve reconstruction remains problematic due to short-term durability of the currently used replacement solutions. We set out to test, for the first time, the suitability of amniotic membrane derived from human placenta for use in cardiovascular replacement of pulmonary valve. Methods The decellularized and preserved amniotic membrane, obtained through our optimised protocol, was characterised for mechanical and hydrodynamic properties in vitro , and then implanted in the RVOT position of two Landrace piglets for in vivo feasibility and performance evaluation. Results Both the in vitro and in vivo assessments showed favourable outcomes. The decellularized amniotic membrane had mechanical properties comparable to the native porcine pulmonary valve leaflets. In hydrodynamic testing, the decellularized amniotic membrane-made valve exhibited favourable opening dynamics, with smooth and coordinated leaflet motion throughout the cycle. In vivo , the decellularized amniotic membrane-based valved conduit showed patency in the short- and long-term with no sign of stenosis or regurgitation. Discussion This study provides an in vivo proof of concept that the decellularized amniotic membrane can be implanted and perform as functional pulmonary valve in a porcine animal model mimicking the clinical scenario of Tetralogy of Fallot surgical correction in infants.
Inversion of the thermomechanical response in nitinol under cyclic loading: an analytical interpretation based on the thermoelastic effect theory
V. Pinto, S. Di Leonardo, G. Pitarresi, G. Burriesci
Mechanics of Materials, 2025
The superelastic behaviour of nitinol is crucial for the design of collapsible and self-expanding cardiovascular implants. Once these are expanded into the host anatomy, the material is predominantly in the austenitic configuration in the majority of the structure, and the cyclic loads acting on the devices are primarily due to small blood pressure variations occurring during the cardiac cycle. Nevertheless, only very few studies have explored the temperature evolution during small cyclic loading of nitinol in a stable austenitic state, reporting an unusual response, where the thermoelastic signal is in phase with the sinusoidal loading wave, rendering the common fundamental law of the thermoelastic effect inapplicable. In this study, infrared thermography (IRT) was employed to investigate the thermomechanical behaviour of an austenitic nitinol specimen under cyclic sinusoidal loading, with increasing amplitude and average strain values. An inversion of the thermomechanical response of nitinol was observed experimentally and explained analytically adopting the higher-order thermoelastic theory. The understanding of the austenitic temperature modulation with the local level of stress allowed to define an IRT approach suitable to quantify the stress levels, knowing the material thermal response and the ratio between mean and amplitude of the applied load. • Thermoelastic response of austenitic nitinol exhibits highly uncommon behaviour. • Standard thermoelastic analysis is inapplicable to common nitinol devices. • The behaviour was found to be well described by the higher-order thermoelastic law. • A first approach to estimate local stress in superelastic nitinol is presented.
Erratum: Author Correction: Valvulogenesis of a living, innervated pulmonary root induced by an acellular scaffold (Communications biology (2023) 6 1 DOI: 10.1038/s42003-023-05383-z.)
Magdi H. Yacoub, Yuan-Tsan Tseng, Jolanda Kluin, Annemijn Vis, Ulrich Stock, Hassiba Smail, Padmini Sarathchandra, Elena Aikawa, Hussam El-Nashar, Adrian H. Chester, Nairouz Shehata, Mohamed Nagy, Amr El-sawy, Wei Li, Gaetano Burriesci, Jacob Salmonsmith, Soha Romeih, Najma Latif
Communications Biology, 2025
In the version of the article initially published, the image shown in the leftmost panel of Fig. 2f was an inadvertent mirrored duplicate of the leftmost image in Fig. 2h; the image in Fig. 2f has now been replaced in the HTML and PDF versions of the article.
Retrokinetics of crystallization
Luke Hunter, Ryo Torii, Gaetano Burriesci, Sergio Bertazzo
Scripta Materialia, 2025
During crystallization, crystals nucleate and grow within materials, often impinging and interacting in a stochastic manner. This complexity has long hindered accurate reconstructions of a material’s crystallization history. By considering a representative material region with a finite crystal population, we derive equations that accurately predict crystal size and free surface evolution throughout the crystallization process. These equations, paired with a numerical solver, enable reconstructing nucleation events and crystallinity progression using the crystal size distribution and growth rates. We demonstrate this method by pinpointing the nucleation and crystallinity timelines of simulated, manufactured, and ancient geological materials, entirely without real-time observation. Our model offers unprecedented insights into extreme crystallization environments that are difficult to mimic, such as volcanic magma chambers, and supports the design of advanced materials.
Hydrodynamic Alterations Produced by Subaortic Membranes: An in Vitro Study
Sofia Di Leonardo, Danila Vella, Calogera Pisano, Vincenzo Argano, Gaetano Burriesci
Irbm, 2025
Background Subaortic stenosis is an aortic disease characterised by the presence of a membrane located at the aortic valve inlet, that causes a sudden reduction of the inflow lumen. The membrane develops as a tissue growth of variable thickness that can cause a major increase in the pressure gradient. In this case, when diagnosed, it is removed by surgical resection. Methods To investigate the haemodynamic alteration introduced by subaortic membranes, an in vitro study was designed and performed. Stiff and flexible membranes were implanted at the inlet of a bioprosthetic control valve. These mock membranes had different radial and angular alignment, modelling concentric and eccentric orifice positions. For each configuration, a range of different membrane lengths was studied, progressively reducing the orifice area at the inlet of the control valve. Results Analysis of the hydrodynamic performances indicates that the detrimental effect of subaortic membranes becomes significant when the membrane orifice areas reduce below 75% of the unobstructed inflow lumen. Video analysis of the valve leaflets dynamics indicates that, together with a worsening in the systolic pressure gradient, the presence of subaortic membranes increases cusps fluttering. As the membrane orifice area reduces, leaflets experience faster oscillation frequencies at decreasing amplitudes. Conclusions The fibromuscular or thin nature of the membrane has a significant role on the severity of the pathology, with higher stiffnesses generally producing worse hydrodynamics. The orifice dimension and position are also important on the systolic performance and can determine potential structural degradation and haematic damage.
Evaluation of NiTi under low-amplitude cyclic loading by means of thermographic harmonic analysis
V. Pinto, R. Cappello, S. Di Leonardo, G. Catalanotti, G. Burriesci, G. Pitarresi
Mechanics of Materials, 2025
Double-loop suture repair of radial meniscal tears provides favourable biomechanical performance compared to conventional repair techniques: A biomechanical study
Antonio Petillo, Alessandro Di Rosa, Carmelo Burgio, Sofia Di Leonardo, Gaetano Burriesci, Francesco Bosco, Ludovico Lucenti, Lawrence Camarda
Journal of Experimental Orthopaedics, 2025
Modelling of thrombus formation, growth and embolisation in the left atrial appendage under atrial fibrillation
Anna Maria Lo Presti, Alessandra Monteleone, Giulio Musotto, Alessandro Tamburini, Enrico Napoli, Gaetano Burriesci
Computers in Biology and Medicine, 2025
A new braided model of the Amulet Amplatzer for accurate simulations of left atrial appendage occlusion procedures
Rafizul Islam Md, Matthew T. Lee, Andrew C. Cook, Jonathan Weir-McCall, Claire A. Martin, Thomas W. Peach, Gaetano Burriesci, Giorgia M. Bosi
Computers in Biology and Medicine, 2025
In Vitro Evaluation of Biomaterials for Heart Valve Prosthesis: High Hydrostatic and Enzymatic Treatments as Alternative for Bio-Derived Materials
Danila Vella, Parnaz Boodagh, Laura Modica De Mohac, Sang‐Ho Ye, Federica Cosentino, Federica Scaglione, Sofia Dei Bardi, Giulia Polizzi, Garrett Coyan, William R. Wagner, Gaetano Burriesci, Antonio D'Amore
Journal of Biomedical Materials Research Part B Applied Biomaterials, 2025
Whitlockite can be a substrate for apatite growth in simulated body fluid
Luke Hunter, Ryo Torii, Gaetano Burriesci, Sergio Bertazzo
Materialia, 2025
Effect of nanocomposite chitosan/hydroxyapatite pH-induced hydrogels on the osteogenic differentiation of spheroids from adipose stem cells
A.B. Di Stefano, C. Di Marco, F. Toia, M. Trapani, M. Testa, S. Di Leonardo, G. Burriesci, M. Franza, E. Cammarata, A. Cordova, F. Lopresti, V. La Carrubba
International Journal of Biological Macromolecules, 2025
Analysis of the haemodynamic changes caused by surgical and transcatheter aortic valve replacements by means fluid-structure interaction simulations
Anna Maria Tango, Alessandra Monteleone, Andrea Ducci, Gaetano Burriesci
Computers in Biology and Medicine, 2025
Photooxidation Cross-Linked, Glutaraldehyde Cross-Linked, or Enzyme and Hydrostatic Pressure Processed Decellularized Biomaterials for Cardiovascular Repair Do Not Affect Host Response in a Rat Right Ventricular Outflow Flow Tract Reconstruction (RVOT) Model
Parnaz Boodagh, Laura Modica De Mohac, Yasurani Hayashi, Danila Vella, Sang‐Ho Ye, Federica Cosentino, Taro Fujii, Emily Gorge, Garrett Coyan, Joan Dario Laubrie Soto, Gaetano Burriesci, William R. Wagner, Antonio D'Amore
Journal of Biomedical Materials Research Part B Applied Biomaterials, 2025
Synchronous Inflation of a Valvuloplasty Balloon Catheter with Heart Rate: In-Vitro Evaluation in Terms of Dilatation Performance
Junke Yao, Xinyi Pi, Giorgia Maria Bosi, Gaetano Burriesci, Helge Wurdemann
IEEE Robotics and Automation Letters, 2025
Impact of trabeculae on thromboembolic risk in the left atrial appendage
Convegno Nazionale Di Bioingegneria, 2025
Fabrication and Validation of a dual stimulation Organ-on-Chip
Convegno Nazionale Di Bioingegneria, 2025
Personalized Stroke Risk Assessment in Atrial Fibrillation Using FluidStructure Interaction and Deep Learning
Giulio Musotto, Danila Vella, Alessandra Monteleone, Nicolina Sciaraffa, Claudia Coronnello, Gaetano Burriesci
Proceedings of the World Congress on Electrical Engineering and Computer Systems and Science, 2025
Development and Characterization of a Blood-Mimicking Fluid for Hemodynamic Research
Convegno Nazionale Di Bioingegneria, 2025
Rheological and morphological insights into Bio-glass 1393 and Car12N incorporation in PLLA and Chitosan scaffolds
Convegno Nazionale Di Bioingegneria, 2025
Fluid-structure interaction analysis of the thromboembolic risk in the left atrial appendage under atrial fibrillation: Effect of hemodynamics and morphological features
Giulio Musotto, Alessandra Monteleone, Danila Vella, Bernardo Zuccarello, Ruggero Cannova, Andrew Cook, Giorgia Maria Bosi, Gaetano Burriesci
Computer Methods and Programs in Biomedicine, 2024
A novel mono-physics particle-based approach for the simulation of cardiovascular fluid-structure interaction problems
Alessandra Monteleone, Sofia Di Leonardo, Enrico Napoli, Gaetano Burriesci
Computer Methods and Programs in Biomedicine, 2024
Left atrial appendage inversion: First computational study to shed light on the phenomenon
Danila Vella, Giulio Musotto, Andrew Cook, Giorgia Maria Bosi, Gaetano Burriesci
Heliyon, 2024
Finite Element and Fluid-Structure Interaction Modeling of a Balloon Catheter
Junke Yao, Jacob Salmonsmith, Giorgia Maria Bosi, Gaetano Burriesci, Helge Wurdemann
IEEE Transactions on Medical Robotics and Bionics, 2024
Effect of the apron in the mechanical characterisation of hyperelastic materials by means of biaxial testing: A new method to improve accuracy
Sofia Di Leonardo, Alessandra Monteleone, Patrizia Caruso, Hugo Meecham-Garcia, Giuseppe Pitarresi, Gaetano Burriesci
Journal of the Mechanical Behavior of Biomedical Materials, 2024
Temperature Harmonic Analysis Of Austenitic Niti Under Dynamic Cyclic Loading
Valentina Pinto, Sofia Di Leonardo, Maria Galeazzo, Gaetano Burriesci, Giuseppe Pitarresi
Proceedings of the World Congress on New Technologies, 2024
Mitral Regurgitation And Atrial Fibrillation: An Explorative FluidStructure Interaction Study
Giulio Musotto, Alessandra Monteleone, Danila Vella, Leon Menezes, Andrew Cook, Giorgia Maria Bosi, Gaetano Burriesci
Proceedings of the World Congress on New Technologies, 2024
On preserving anatomical detail in statistical shape analysis for clustering: focus on left atrial appendage morphology
Matthew T. Lee, Vincenzo Martorana, Rafizul Islam Md, Raphael Sivera, Andrew C. Cook, Leon Menezes, Gaetano Burriesci, Ryo Torii, Giorgia M. Bosi
Frontiers in Network Physiology, 2024
Compliant Aortic Annulus Sizing With Different Elliptical Ratios Through a Valvuloplasty Balloon Catheter
Junke Yao, Giorgia Maria Bosi, Andrea Palombi, Gaetano Burriesci, Helge Wurdemann
IEEE Transactions on Biomedical Engineering, 2023
Valvulogenesis of a living, innervated pulmonary root induced by an acellular scaffold
Magdi H. Yacoub, Yuan-Tsan Tseng, Jolanda Kluin, Annemijn Vis, Ulrich Stock, Hassiba Smail, Padmini Sarathchandra, Elena Aikawa, Hussam El-Nashar, Adrian H. Chester, Nairouz Shehata, Mohamed Nagy, Amr El-sawy, Wei Li, Gaetano Burriesci, Jacob Salmonsmith, Soha Romeih, Najma Latif
Communications Biology, 2023
Hydrodynamic ex vivo analysis of valve-sparing techniques: assessment and comparison
Sofia Di Leonardo, Danila Vella, Carmelo Savio Grillo, Carla Martorana, Salvatore Torre, Vincenzo Argano, Gaetano Burriesci
European Journal of Cardio Thoracic Surgery, 2023
Elastic properties of 2D auxetic honeycomb structures- a review
Ebba Montgomery-Liljeroth, Silvia Schievano, Gaetano Burriesci
Applied Materials Today, 2023
Modelling of thrombus formation using smoothed particle hydrodynamics method
Alessandra Monteleone, Alessia Viola, Enrico Napoli, Gaetano Burriesci
Plos One, 2023
Comparative Assessment of Prosthetic Biomaterials for Cardiac Applications
Danila Vella, Parnaz Boodagh, Laura Modica de Mohac, Federica Cosentino, Federica Scaglione, William Wagner, Antonio D’Amore, Gaetano Burriesci
Proceedings of the World Congress on Electrical Engineering and Computer Systems and Science, 2023
A distributed-memory MPI parallelization scheme for multi-domain incompressible SPH
Alessandra Monteleone, Gaetano Burriesci, Enrico Napoli
Journal of Parallel and Distributed Computing, 2022
The Role of Patient-Specific Morphological Features of the Left Atrial Appendage on the Thromboembolic Risk Under Atrial Fibrillation
Giulio Musotto, Alessandra Monteleone, Danila Vella, Sofia Di Leonardo, Alessia Viola, Giuseppe Pitarresi, Bernardo Zuccarello, Antonio Pantano, Andrew Cook, Giorgia M. Bosi, Gaetano Burriesci
Frontiers in Cardiovascular Medicine, 2022
Biological Equivalence of GGTA-1 Glycosyltransferase Knockout and Standard Porcine Pericardial Tissue Using 90-Day Mitral Valve Implantation in Adolescent Sheep
Christopher McGregor, Jacob Salmonsmith, Gaetano Burriesci, Guerard Byrne
Cardiovascular Engineering and Technology, 2022
Standard mechanical testing is inadequate for the mechanical characterisation of shape-memory alloys: Source of errors and a new corrective approach
Sofia Di Leonardo, Giuseppe Pitarresi, Gaetano Burriesci
Materials and Design, 2022
Fluid–structure interaction approach with smoothed particle hydrodynamics and particle–spring systems
Alessandra Monteleone, Guido Borino, Enrico Napoli, Gaetano Burriesci
Computer Methods in Applied Mechanics and Engineering, 2022
Computational Analysis of Balloon Catheter Behaviour at Variable Inflation Levels
Junke Yao, Giorgia Maria Bosi, Gaetano Burriesci, Helge Wurdemann
Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society EMBS, 2022
Investigation of the thermomechanical response of cyclically loaded niti alloys by means of temperature frequency domain analyses
Sofia Di Leonardo, Riccardo Cappello, Gaetano Burriesci, Giuseppe Pitarresi
Materials, 2021
Experimental Validation of Enhanced Magnetic Resonance Imaging (EMRI) Using Particle Image Velocimetry (PIV)
Giacomo Annio, Ryo Torii, Andrea Ducci, Vivek Muthurangu, Victor Tsang, Gaetano Burriesci
Annals of Biomedical Engineering, 2021
In silico study of the ageing effect upon aortic valves
Anna Maria Tango, Andrea Ducci, Gaetano Burriesci
Journal of Fluids and Structures, 2021
Effect of the Alterations in Contractility and Morphology Produced by Atrial Fibrillation on the Thrombosis Potential of the Left Atrial Appendage
Danila Vella, Alessandra Monteleone, Giulio Musotto, Giorgia Maria Bosi, Gaetano Burriesci
Frontiers in Bioengineering and Biotechnology, 2021
In Vitro and Ex Vivo Hemodynamic Testing of an Innovative Occluder for Paravalvular Leak After Transcather Aortic Valve Implantation
Paolo Peruzzo, Gaetano Burriesci, Francesca Maria Susin, Andrea Colli
Journal of Cardiovascular Translational Research, 2019
The neochord mitral valve repair procedure: Numerical simulation of different neochords tensioning protocols
Luigi Di Micco, Paolo Peruzzo, Andrea Colli, Gaetano Burriesci, Daniela Boso, Laura Besola, Gino Gerosa, Francesca M. Susin
Medical Engineering and Physics, 2019
Does transcatheter aortic valve alignment matter?
Jacob Andrew Salmonsmith, Andrea Ducci, Gaetano Burriesci
Open Heart, 2019
Incidence, predictors and cerebrovascular consequences of leaflet thrombosis after transcatheter aortic valve implantation: A systematic review and meta-analysis
Fabrizio D’Ascenzo, Stefano Salizzoni, Andrea Saglietto, Martina Cortese, Azeem Latib, Anna Franzone, Marco Barbanti, Fabian Nietlispach, Erik W Holy, Gaetano Burriesci, Alessandro De Paoli, Paolo Fonio, Francesco Atzeni, Claudio Moretti, Leor Perl, Maurizio D’Amico, Mauro Rinaldi, Federico Conrotto
European Journal of Cardio Thoracic Surgery, 2019
A Durable Porcine Pericardial Surgical Bioprosthetic Heart Valve: a Proof of Concept
Benyamin Rahmani, Christopher McGregor, Guerard Byrne, Gaetano Burriesci
Journal of Cardiovascular Translational Research, 2019
In vitro assessment of pacing as therapy for aortic regurgitation
Paolo Peruzzo, Francesca Maria Susin, Andrea Colli, Gaetano Burriesci
Open Heart, 2019
Sizing the aortic annulus with a robotised, commercially available soft balloon catheter: In vitro study on idealised phantoms
Andrea Palombi, Giorgia M Bosi, Sara Di Giuseppe, Elena De Momi, Shervanthi Homer-Vanniasinkam, Gaetano Burriesci, Helge A Wurdemann
Proceedings IEEE International Conference on Robotics and Automation, 2019
3D printing assisted finite element analysis for optimising the manufacturing parameters of a lumbar fusion cage
Elena Provaggi, Claudio Capelli, Benyamin Rahmani, Gaetano Burriesci, Deepak M. Kalaskar
Materials and Design, 2019
Validation and Extension of a Fluid–Structure Interaction Model of the Healthy Aortic Valve
Anna Maria Tango, Jacob Salmonsmith, Andrea Ducci, Gaetano Burriesci
Cardiovascular Engineering and Technology, 2018
Computational Fluid Dynamic Analysis of the Left Atrial Appendage to Predict Thrombosis Risk
Giorgia Maria Bosi, Andrew Cook, Rajan Rai, Leon J. Menezes, Silvia Schievano, Ryo Torii, Gaetano Burriesci
Frontiers in Cardiovascular Medicine, 2018
Anatomically realistic ultrasound phantoms using gel wax with 3D printed moulds
Efthymios Maneas, Wenfeng Xia, Daniil I Nikitichev, Batol Daher, Maniragav Manimaran, Rui Yen J Wong, Chia-Wei Chang, Benyamin Rahmani, Claudio Capelli, Silvia Schievano, Gaetano Burriesci, Sebastien Ourselin, Anna L David, Malcolm C Finlay, Simeon J West, Tom Vercauteren, Adrien E Desjardins
Physics in Medicine and Biology, 2018
Design, Analysis and Testing of a Novel Mitral Valve for Transcatheter Implantation
Selim Bozkurt, Georgia L. Preston-Maher, Ryo Torii, Gaetano Burriesci
Annals of Biomedical Engineering, 2017
In Vitro Hydrodynamic Assessment of a New Transcatheter Heart Valve Concept (the TRISKELE)
Benyamin Rahmani, Spyros Tzamtzis, Rose Sheridan, Michael J Mullen, John Yap, Alexander M. Seifalian, Gaetano Burriesci
Journal of Cardiovascular Translational Research, 2017
Pledget-Armed Sutures Affect the Haemodynamic Performance of Biologic Aortic Valve Substitutes: A Preliminary Experimental and Computational Study
Claudio Capelli, Chiara Corsini, Dario Biscarini, Francesco Ruffini, Francesco Migliavacca, Alfred Kocher, Guenther Laufer, Andrew M. Taylor, Silvia Schievano, Martin Andreas, Gaetano Burriesci, Claus Rath
Cardiovascular Engineering and Technology, 2017
Transcatheter aortic valves produce unphysiological flows which may contribute to thromboembolic events: An in-vitro study
Andrea Ducci, Francesco Pirisi, Spyridon Tzamtzis, Gaetano Burriesci
Journal of Biomechanics, 2016
Physiological vortices in the sinuses of Valsalva: An in vitro approach for bio-prosthetic valves
Riccardo Toninato, Jacob Salmon, Francesca Maria Susin, Andrea Ducci, Gaetano Burriesci
Journal of Biomechanics, 2016
Can finite element models of ballooning procedures yield mechanical response of the cardiovascular site to overexpansion?
Giorgia M. Bosi, Benedetta Biffi, Giovanni Biglino, Valentina Lintas, Rod Jones, Spyros Tzamtzis, Gaetano Burriesci, Francesco Migliavacca, Sachin Khambadkone, Andrew M. Taylor, Silvia Schievano
Journal of Biomechanics, 2016
Physical equivalency of wild type and galactose α 1,3 galactose free porcine pericardium; a new source material for bioprosthetic heart valves
Christopher McGregor, Guerard Byrne, Benyamin Rahmani, Elisa Chisari, Konstantina Kyriakopoulou, Gaetano Burriesci
Acta Biomaterialia, 2016
A new transcatheter heart valve concept (the TRISKELE): Feasibility in an acute preclinical model
Benyamin Rahmani, Spyros Tzamtzis, Rose Sheridan, Michael J. Mullen, John Yap, Alexander M. Seifalian, Gaetano Burriesci
Eurointervention, 2016
Impact of different aortic valve calcification patterns on the outcome of transcatheter aortic valve implantation: A finite element study
Francesco Sturla, Mattia Ronzoni, Mattia Vitali, Annalisa Dimasi, Riccardo Vismara, Georgia Preston-Maher, Gaetano Burriesci, Emiliano Votta, Alberto Redaelli
Journal of Biomechanics, 2016
Novel heart valve prosthesis with self-endothelialization potential made of modified polyhedral oligomeric silsesquioxane-nanocomposite material
Hossein Ghanbari, Dina Radenkovic, Sayed Mahdi Marashi, Shirin Parsno, Nima Roohpour, Gaetano Burriesci, Alexander M. Seifalian
Biointerphases, 2016
To the Editor [1]
Hoda Hatoum, Juan A. Crestanello, Lakshmi Prasad Dasi
New England Journal of Medicine, 2016
Numerical model of a valvuloplasty balloon: In vitro validation in a rapid-prototyped phantom
Benedetta Biffi, Giorgia M. Bosi, Valentina Lintas, Rod Jones, Spyros Tzamtzis, Gaetano Burriesci, Francesco Migliavacca, Andrew M. Taylor, Silvia Schievano, Giovanni Biglino
Biomedical Engineering Online, 2016
In vitro hemodynamic testing of Amplatzer plugs for paravalvular leak occlusion after transcatheter aortic valve implantation
Gaetano Burriesci, Paolo Peruzzo, Francesca Maria Susin, Giuseppe Tarantini, Andrea Colli
International Journal of Cardiology, 2016
A Technical Review of Minimally Invasive Mitral Valve Replacements
Georgia L. Preston-Maher, Ryo Torii, Gaetano Burriesci
Cardiovascular Engineering and Technology, 2015
Finite element analysis of transcatheter aortic valve implantation in the presence of aortic leaflet calcifications
Annalisa Dimasi, Marco Stevanella, Emiliano Votta, Francesco Sturla, Gaetano Burriesci, Alberto Redaelli
Lecture Notes in Applied and Computational Mechanics, 2015
Uniaxial and buckling mechanical response of auxetic cellular tubes
Nicholas Karnessis, Gaetano Burriesci
Smart Materials and Structures, 2013
Hemodynamics in the Valsalva sinuses after transcatheter aortic valve implantation (TAVI).
Journal of Heart Valve Disease, 2013
Numerical analysis of the radial force produced by the Medtronic-CoreValve and Edwards-SAPIEN after transcatheter aortic valve implantation (TAVI)
S. Tzamtzis, J. Viquerat, J. Yap, M.J. Mullen, G. Burriesci
Medical Engineering and Physics, 2013
Polymeric Heart Valves
Benyamin Rahmani, Hossein Ghanbari, Spyridon Tzamtzis, Gaetano Burriesci, Alexander M. Seifalian
Encyclopedia of Biophysics, 2013
Fluid-structure interaction simulation of the edge-to-edge repair of the mitral valve in functional and degenerative states
K. D. Lau, G. Burriesci, V. Díaz-Zuccarini
ASME 2012 Summer Bioengineering Conference Sbc 2012, 2012
Manufacturing and hydrodynamic assessment of a novel aortic valve made of a new nanocomposite polymer
Benyamin Rahmani, Spyridon Tzamtzis, Hossein Ghanbari, Gaetano Burriesci, Alexander M. Seifalian
Journal of Biomechanics, 2012
A new generation of aortic valve prosthesis: Design, manufacture and hydrodynamic assessment
Benyamin Rahmani, Hossein Ghanbari, Spyridon Tzamtzis, Gaetano Burriesci, Alexander M. Seifalian
ASME 2012 Summer Bioengineering Conference Sbc 2012, 2012
Fluid-structure interaction study of the edge-to-edge repair technique on the mitral valve
K.D. Lau, V. Díaz-Zuccarini, P. Scambler, G. Burriesci
Journal of Biomechanics, 2011
Mitral valve dynamics in structural and fluid-structure interaction models
K.D. Lau, V. Diaz, P. Scambler, G. Burriesci
Medical Engineering and Physics, 2010
Design of a novel polymeric heart valve
G. Burriesci, F. Cavallo Marincola, C. Zervides
Journal of Medical Engineering and Technology, 2010
The anti-calcification potential of a silsesquioxane nanocomposite polymer under in vitro conditions: Potential material for synthetic leaflet heart valve
Hossein Ghanbari, Asmeret G. Kidane, Gaetano Burriesci, Bala Ramesh, Arnold Darbyshire, Alexander M. Seifalian
Acta Biomaterialia, 2010
WCE 2010 - World Congress on Engineering 2010: Preface
Wce 2010 World Congress on Engineering 2010, 2010
WCE 2010 - World Congress on Engineering 2010: Preface
Wce 2010 World Congress on Engineering 2010, 2010
Adaptation and development of software simulation methodologies for cardiovascular engineering: Present and future challenges from an end-user perspective
V. Díaz-Zuccarini, A.J. Narracott, G. Burriesci, C. Zervides, D. Rafiroiu, D. Jones, D.R. Hose, P.V. Lawford
Philosophical Transactions of the Royal Society A Mathematical Physical and Engineering Sciences, 2009
Polymeric heart valves: new materials, emerging hopes
Hossein Ghanbari, Helene Viatge, Asmeret G. Kidane, Gaetano Burriesci, Mehdi Tavakoli, Alexander M. Seifalian
Trends in Biotechnology, 2009
Manufacture of small calibre quadruple lamina vascular bypass grafts using a novel automated extrusion-phase-inversion method and nanocomposite polymer
Sandip Sarkar, Gaetano Burriesci, Adam Wojcik, Nicholas Aresti, George Hamilton, Alexander M. Seifalian
Journal of Biomechanics, 2009
A novel nanocomposite polymer for development of synthetic heart valve leaflets
Asmeret G. Kidane, Gaetano Burriesci, Mohan Edirisinghe, Hossein Ghanbari, Philipp Bonhoeffer, Alexander M. Seifalian
Acta Biomaterialia, 2009
Current developments and future prospects for heart valve replacement therapy
Asmeret G. Kidane, Gaetano Burriesci, Patricia Cornejo, Audrey Dooley, Sandip Sarkar, Philipp Bonhoeffer, Mohan Edirisinghe, Alexander M. Seifalian
Journal of Biomedical Materials Research Part B Applied Biomaterials, 2009
Percutaneous Heart Valve Replacement: An Update
Hossein Ghanbari, Asmeret G. Kidane, Gaetano Burriesci, Philipp Bonhoeffer, Alexander M. Seifalian
Trends in Cardiovascular Medicine, 2008
An approach to the simulation of fluid-structure interaction in the aortic valve
C.J. Carmody, G. Burriesci, I.C. Howard, E.A. Patterson
Journal of Biomechanics, 2006
Mechanical and electromagnetic behaviour of auxetic honeycomb structures
F. Scarpa, F. C. Smith, B. Chambers, G. Burriesci
Aeronautical Journal, 2003
Computer aided photoelasticity by an optimum phase stepping method
Sandro Barone, Gaetano Burriesci, Giovanni Petrucci
Experimental Mechanics, 2002
Simultaneous optimization of the electromagnetic and mechanical properties of honeycomb materials
Frank C. Smith, Fabrizio L. Scarpa, G. Burriesci
Proceedings of SPIE the International Society for Optical Engineering, 2002
Influence of anisotropy on the mechanical behaviour of bioprosthetic heart valves
G. Burriesci, I. C. Howard, E. A. P
Journal of Medical Engineering and Technology, 1999