Taha Nazir

Taha Nazir was awarded the Ph.D Microbiology in 2010; M.Phil Pharmacology 2000 and graduation in pharmacy in 1997. Dr. Nazir has ≤25 year’s research, academic and professional experience along with exceptional knowledge epidemiology, cell pathology, molecular biology and biotechnology. He has sufficient teaching experience to the graduate and post-graduate students in different universities. That assumed to lead the responsibility of developing curriculum, designing programs and deploying the projects in defined budgetary order. The institutional needs of those that are a part of the organization often dictate him regarding the scope and magnitude the projects. Thus, Dr. Nazir has played multitudinous roles in a variety of academic, scientific and professional capacities/ positions. Additionally, he has strong experience of writing, reviewing, and publishing the research manuscripts. Because he compiled seven books and published ≤80 research articles published in accredited scientific

EDUCATION

B.Pharm., M.Phil., PhD

RESEARCH INTERESTS

Microbiology; Pharmacology; Pharmacist.

Scopus Publications

History and Clinical Development of Nanomedicines, Nanostructure, and Nanoscale Sciences
Alternative Therapies in Health and Medicine, 2023
The Role of Pro-Inflammatory Mediator Interleukin-32 in Osteoclast Differentiation
Taha NAZIR, Nida TAHA, Azharul ISLAM, Ishtiaq RABBI, Pervaiz Akhter SHAH
Turkish Journal of Pharmaceutical Sciences, 2023
The recently explained cytokine, which is produced after the stimulation of interferon (IFN)-c, interleukin (IL)-2, and IL-18 is IL-32, has pro-inflammatory IFN-c, IL-2 and IL-18 are IL-32 mediator's properties that are generally entailed in many diseases, including infections, cancer, and chronic inflammation. After the initial statement in 2005, it promoted the osteoclast precursor's differentiation into TRAcP plus VNR plus multinucleated cells that express explicit osteoclast indicators. Furthermore, the loss of bone resorption might be accredited because of the collapse of the multinucleated cells, which are produced of the reaction to IL-32 to direct factoring that is ultimately essential for attaching the cells for bone resorption. Thus, in conclusion, IL-32, the pro-inflammatory mediator, has an important and indirect role in regulating osteoclast differentiation. In bone disorder's pathophysiology, critical role of IL-32 needs more scientific evidence to develop a rational treatment protocol. IL-32 can become a potent mediator of active osteoclast generation in the presence of receptor activator of NF-κB ligand (RANKL). This novel cytokine can introduce more favorable conditions for osteoclastogenesis in the rheumatic arthritis by increasing the RANKL and osteoprotegerin ratio in fibroblast-like synoviocytes.
Formulation Development and In vitro Characterization of Omperazole Floating Tablets by Using Eudragit and HPMC
Latin American Journal of Pharmacy, 2023
Esomeprazole Floating Tablets by Using HUSK/HPMC Polymers: Formulation Development and In-vitro Characterization
Latin American Journal of Pharmacy, 2023
Medicinal Plants and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) in Treatment of Arthritis: A Literature Review
Alternative Therapies in Health and Medicine, 2022
The Potentially Recommended Pharmacotherapy for COVID-19
Alternative Therapies in Health and Medicine, 2021
Biochemical dynamics and clinical features of novel corona virus (2019-NCOV)
Alternative Therapies in Health and Medicine, 2020
Developing methods for the evaluation of isotonicity of parenteral products
Latin American Journal of Pharmacy, 2020
Formulation, evaluation and in vitro characterization of gastroretentive floating tablet of diclofenac sodium
Pakistan Journal of Pharmaceutical Sciences, 2019
Currently a variety of tools and techniques are used to deliver complex medicines. Whereas, certain advanced methods assure the safety and usefulness by regulating the pharmacokinetic and pharmacodynamic. Thus, we aimed this study to develop a novel gastro retentive floating tablets. The formulation was designed to provide the desired controlled and complete release of drug for prolonged period of time. The formulations were evaluated for physical characterization. The obtained results of hardness (4.6-5.1), friability (0.20-0.43%), weight variation (350 ±2 - 350±5) and in vitro buoyancy were found within official limits of United Stated Pharmacopoeia (USP). Whereas, the F-7 showed most optimized intra gastric floating characteristics and exhibited 93.87% release of diclofenac sodium in 9 hours. The Floating Lag Time of 8 minutes and Total Floating Time ≥12 hours were recorded. In-vitro drug release kinetics evaluated using the linear regression method was found to follow the Zero Order and Peppas model for the release of both the drugs. DSC thermograph and FTIR spectra depicted that there was no chemical incompatibility between drugs and polymers. In conclusion the desgined tablet can be use in clinical practice as model drug. Because, the precompression and post-compression parameters were satisfactory and within desired limits.
Role of chitosan, carboxy methyl cellulos, polyvinyl pyrrolidone, kyron T134 and primogel to design the mouth disintegrating telmisartan tablet with extended release profile
Muhammad Abdullah Akram, Nida Taha, Taha Nazir
Indonesian Journal of Pharmacy, 2017
The Mouth Disintegrating Extended Release Telmisartan (MDERT) tablets are designed for adequate pharmacokinetic profile to avoid the unusual peaks and troughs. Although, there are extensive advance techniques used to deliver drugs. But oral route is still remains effective in most of the therapeutical situations. Thus we aimed this study to formulate a dosage form with dual character of orodispersion as well as extended effectiveness. MDERTS dosage form was prepared by direct compression method. The major components of this preparation were Telmisartan (TLM), Carboxy methyl cellulose polyvinyl Pyrrolidone, Chitosan, Talc, Mg-stearate, Lactose. The MDERTS dosage form was characterized with different determinants. While, the drug release curves of all 6 formulations upto 12h, DSC spectra of TLM, Kyron T 134 , Primogel, TLM+Kyron T 134 +Primogel, Chitosan, CMC and different excepients are presented as comprehensive scientific figures. DSC and FTIR spectroscopic studies indicate the compatibility of drugs with each other and with excipients. Moreover, the formulation F2 containing more than 10% of Kyron T had shown best results. Whereas, the overall results had shown that Kyron T containing tablets had best, in vitro dispersion time, wetting time and wetting volume, water absorption ratio. The order in which superdisintegrants and polymers had produced desirable effect is Kyron T134 > Kyron T134134 + primogel > primogel and for polymers chitosan> chitosan+CMC> chitosan +PVP> CMC> CMC+PVP> PVP. Thus, Kyron T is the best superdisintegrant of others which were used in present study and direct compression method is the best used to prepare extended release mouth disintegrating tablets.
Monocytopenia; induction by vinorelbine, cisplatin and doxorubicin in breast, non-small cell lung and cervix cancer patients
International Journal of Health Science, 2016
Review of pharmacy professionals and drug jurisprudence to achieve the millennium development goals in Punjab province of Pakistan
Taha Nazir, Azharul Islam, Nida Taha, Saeed Urasheed Nazir, Muhammad Ather Chaudhary, Muhammad Iqbal
Indian Journal of Pharmaceutical Education and Research, 2016
Lymphocytopenia; Induced by vinorelbine, doxorubicin and cisplatin in human cancer patients
Taha Nazir, Azharul Islam, Muhammad Ovais Omer, Mazhar Mustafa
Breast Disease, 2015
Neutropenia induction by vinorelbine alone and in combination with doxorubicin and cisplatin in cancer patients
Healthmed, 2011
Avoidable childhood death: A case of mismanagement and inappropriate medication use
Taha Nazir
African Journal of Pharmacy and Pharmacology, 2011
Eosinopenia induction by vinorelbine alone and in combination with doxorubicin and cisplatin in cancer patients
Pharmacologyonline, 2010
Ethambutol resistance of indigenous Mycobacterium tuberculosis isolated from human patients
Taha Nazir, Muhammad Hidayat Rasool, Abdul Hameed, Bashir Ahmad, Javed Anver Qureshi
Brazilian Journal of Microbiology, 2010
Rifampicin resistance profile of Mycobacterium tuberculosis isolated from human patients
Proceedings of the Pakistan Academy of Sciences, 2009
Study of anemic syndrome induced by vinorelbine, doxorubicin and cisplatin in human cancer patients
Pharmacologyonline, 2009

RECENT SCHOLAR PUBLICATIONS

Microbial mastery of life: How microscopic reproduction shapes evolution, ecology, and survival
T Nazir
Pharm Rev 17, 52-55 , 2026
2026
MUSHTAQ AHMAD KHAN’S RESIGNATION FROM JAMAAT-E-ISLAMI: A CRITICAL EXAMINATION IDEOLOGYAUTONOMYAND ORGANIZATIONAL DISCIPLINE IN PAKISTAN’S RELIGIOUS POLITICS
T Nazir
2025
AghaazInfoMediaSystem (AIMS)
T Nazir
2025
MOLECULAR CHARACTERIZATION, CLINICAL MANAGEMENT AND DEVELOPMENT OF THE VACCINES AGAINST THE TARGETED VIRAL COMPONENTS OF COVID-19.
T Nazir, M Ahmed, HA Mirza, N Taha
Military Medical Science Letters/Vojenské zdravotnické Listy 94 (2) , 2025
2025
The Bureaucratic Control and Authoritarian Governance of University Teaching Staff via Attendance Recording Systems: Potential Impediments to Academic Innovation, Excellence …
T Nazir
2025
CRISPR/CAS Genome Editing Technology: Implications And Challenges
T Nazir, A Islam, HA Mirza, S Radwan, N Taha
Preprints , 2024
2024
CRISPR-Cas Associated Cells and Animal Mediated Biomedical Modelling
T Nazir, HA Mirza, N Rao
Preprints , 2024
2024
Crispr-cas System: Classification, Benefits, Applications And Function
T Nazir, HA Mirza, N Taha
Preprints , 2024
2024
Gene Editing, Indiscriminate Degradation And Recyclic Catalytic Events In Crispr Cas Technology
T Nazir, HA Mirza, S Radwan, N Taha
Preprints , 2024
2024
History, Development and Characteristics of CRISPR-Cas System
T Nazir, H Mirza, N Taha
Preprints , 2024
2024
Citations: 1
History and Clinical Development of Nanomedicines, Nanostructure, and Nanoscale Sciences
T Nazir, M Ahmed, H Mirza, N Taha
Altern Ther Health Med 29 (6), 25-29 , 2023
2023
Citations: 1
The role of pro-inflammatory mediator Interleukin-32 in osteoclast differentiation
T Nazir, T Nida, A Islam, I Rabbi, PA Shah
Turkish Journal of Pharmaceutical Sciences 20 (2), 121 , 2023
2023
Citations: 2
Formulation Development and In vitro Characterization of Omperazole Floating Tablets by Using Eudragit and HPMC
PA Shah, Y Kamal, FA Razzaq, HM Ramzan, A Shoukat, A Pervaiz, ...
LATIN AMERICAN JOURNAL OF PHARMACY 42 (6), 1148-1154 , 2023
2023
Esomeprazole Floating Tablets by Using HUSK/HPMC Polymers: Formulation Development and In-vitro Characterization
PA Shah, Y Kamal, FA Razzaq, HM Ramzan, A Shoukat, A Pervaiz, ...
Lat. Am. J. Pharm 42 (6), 1133-9 , 2023
2023
Citations: 1
CONCEALMENT OF FACTS AND HIDING INFORMATION REGARDING THE ILLEGAL APPOINTMENT OF PROFESSOR OF PHARMACY IN PUBLIC SECTOR UNIVERSITY OF PAKISTAN.
T Nazir
2023
Assessment of knowledge and health related quality of life among chronic obstructive pulmonary disease patients: an observational study
M Iqbal, M Sultana, H Riaz, R Shamim, SS Munir, T Nazir, SUR Nazir, ...
Journal of Peoples University of Medical & Health Sciences Nawabshah.(JPUMHS … , 2022
2022
Citations: 2
Theranostics Usage of Nano Drug Complexes in Clinical Patientcare
T Nazir, SUR Nazir, H Riaz, PA Shah, M Sultana, SS Munir, ...
Journal of Pharmaceutical Research International 34 (49A), 18-25 , 2022
2022
Saussurea costus as herbal medicines have im-munomodulatory and potential nutraceutical components that may help in covid-19 remedy
MM Elmaghrabi, NM Majrashi, DS Alharbi, NA Marraiki, T Nazir, U Farooq, ...
Adv Biomed Sci 7, 1-14 , 2022
2022
Citations: 2
ANOTHER PIECE OF BEAUTIFUL CORRUPTION MOCKING THE ADMINISTRATION OF THE HONORABLE CHANCELLOR/GOVERNOR PUNJAB, HEC’S QUALITY ASSURANCE AND ACCOUNTABILITY SYSTEM OF NATIONAL …
T Nazir
2022
POTENTIAL THREATS OF ORDINARY INVESTIGATION AND LITIGATION MODEL OF THE NATIONAL ACCOUNTABILITY BUREAU ON THE PHARMACEUTICAL AND HEALTH SYSTEM IN PAKISTAN.
T Nazir
2022

MOST CITED SCHOLAR PUBLICATIONS

Monocytopenia; induction by vinorelbine, cisplatin and doxorubicin in breast, non-small cell lung and cervix cancer patients
T Nazir, N Taha, A Islam, S Abraham, A Mahmood, M Mustafa
International journal of health sciences 10 (4), 542 , 2016
2016
Citations: 29
Antibacterial activity of black tea against streptococcus mutans and its synergism with antibiotics
T Mughal, A Tahir, S Qureshi, T Nazir, M Rasheed
J App Pharm 2 (2), 60-67 , 2010
2010
Citations: 25
Emergence of potential superbug mycobacterium tuberculosis, lessons from New Delhi mutant-1 bacterial strains
T Nazir, S Abraham, A Islam
International journal of health sciences 6 (1), 87 , 2012
2012
Citations: 23
Lymphocytopenia; induced by vinorelbine, doxorubicin and cisplatin in human cancer patients
T Nazir, A Islam, MO Omer, M Mustafa
Breast disease 35 (1), 1-4 , 2015
2015
Citations: 19
Designing, development and formulation of mouth disintegrating telmisartan tablet with extended release profile using response surface methodology
MA Akram, T Nazir, N Taha, A Adil, M Sarfraz, SR Nazir
J. Bioequiv. Availab 7, 262-266 , 2015
2015
Citations: 16
Studies of ketoprofen toxicity in avian species
AF Awan, T Nazir
Journal of Basic & Applied Sciences 7 (2) , 2011
2011
Citations: 11
Medicinal Plants and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) in Treatment of Arthritis: A Literature Review.
R Shamim, M Sultana, SUR Nazir, H Riaz, T Nazir, A Islam
Alternative Therapies in Health and Medicine , 2021
2021
Citations: 10
Rifampicin resistance profile of Mycobacterium tuberculosis isolated from human patients
T Nazir, A Hameed, JA Qureshi, B Ahmad, S Abraham
Proc. Pakistan Acad. Sci 46 (3), 131-136 , 2009
2009
Citations: 8
Review of pharmacy professionals and drug jurisprudence to achieve the millennium development goals in punjab province of Pakistan
T Nazir, A Islam, N Taha, SU Nazir, MA Chaudhary, M Iqbal
Indian J Pharm Educ Res 50 (1), 24-33 , 2016
2016
Citations: 7
Review of the basic components of clinical pharmaceutical care in Pakistan
T Nazir, SMM Zaidi
Can J App Sci 1 (3), 168-173 , 2011
2011
Citations: 7
Pyrazinamide resistance of Mycobacterium tuberculosis strains isolated from human patients
T Nazir
Pharmacol.… , 2008
2008
Citations: 7
Toxicity study of piroxicam in broilers
AF Awan, M Ashraf, A Malik, A Akram, G Murtaza
Latin American Journal of Pharmacy 31 , 2012
2012
Citations: 6
The potentially recommended pharmacotherapy for COVID-19
M Sultana, R Shamim, H Riaz, SS Munir, RR Kayani, S Manzoor, A Islam
Health Med 27 (S1), 24-28 , 2021
2021
Citations: 5
Extended Release Orally Disintegrating Dosage Forms are Potential Techniques to Deliver and Maintain the Therapeutic Ranges of Plasma Drug Concentrations
T Nazir
J App Pharm 7, 001 , 2015
2015
Citations: 4
Studies of dipyrone (metamizole sodium) toxicity in avian species
AF Awan, M Ashraf, O Umer, T Nazir, MS Akhtar, HU Rehman
J. App. Pharm 1 (1), 1-6 , 2009
2009
Citations: 4
Formulation, evaluation and in vitro characterization of gastroretentive floating tablet of diclofenac sodium
N Taha, T Jamil, MA Akram
Pak. J. Pharm. Sci 32 (6), 2573-2578 , 2019
2019
Citations: 3
Neutropenia induction by vinorelbine alone and in combination with doxorubicin and cisplatin in cancer patients
T Nazir, Habib-Ur-Rehman, O Omar, TA Mughal
HEALTHMED 5 (3), 486-490 , 2011
2011
Citations: 3
THROMBOCYTOPENIA INDUCED BY VINORELBINE, DOXORUBICIN AND CISPLATIN IN HUMAN CANCER PATIENTS
MM Taha Nazir, M Ashraf, MO Omer, S Abraham, KF Hashmi, N Taha, ...
Journal of Applied Pharmacy 1, 16-20 , 2009
2009
Citations: 3
Study of phenylbutazone toxicity in avian species
AF Awan, T Nazir, M Ashraf, O Umer, HU Rehman
Pak J Pharm 16, 25-28 , 2003
2003
Citations: 3
The role of pro-inflammatory mediator Interleukin-32 in osteoclast differentiation
T Nazir, T Nida, A Islam, I Rabbi, PA Shah
Turkish Journal of Pharmaceutical Sciences 20 (2), 121 , 2023
2023
Citations: 2

Publications

1. Nazir SUR, Nazir T, Sultana M, Shamim R, Riaz H, Sultana Munir S, Kayani RR, Manzoor S, Islam A. (2021). The Potentially Recommended Pharmacotherapy for COVID-19. Altern Ther Health Med. June, 2021 - VOL. 27, NO. 7. PMID: 33373324.
2. Ruqaiya Rasheed Kayani, Rahat Shamim, Safia Sultana Munir, Misbah Sultana, Saeed Ur Rashid Nazir, Humayun Riaz, Taha Nazir, Muhammad Maaz Ali; Azharul Islam. (2021). Medicinal Plants and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) in Treatment of Arthritis: A Literature Review. Alternative Therapies. 3470 Washington Drive Suite Eagan MN 55122 USA. 2021 - Vol. 27
3. Azharul Islam, Saba Manzoor, Saeed Ur Rashid Nazir, Taha Nazir, Ruqaiya Rasheed Kayani, Humayun Riaz, Misbah Sultana, Nida Taha (2020). Biochemical Dynamics and Clinical Features of Novel Corona Virus (2019-nCoV). Alternative Therapies. 3470 Washington Drive Suite Eagan MN 55122 USA. April, 2020 - VOL. 26, NO. 8
4. Nazir T, Taha N, Naveed S, Sadia H, Nazir SR, Rehman A, Farooq M. Efficacy and sensitivity of the Peg Interferon Alpha-3 million units against HCV-RNA Genotype 3A given to the confirmed of new and relapsed human patients. JPUMHS;2020;10(03)
5. Taha Nazir, Saeed Ur Rashid Nazir, Misbah Sultana, Humayun Riaz, Muhammad Naeem Qaisar, Nida Taha, Muhammad Amer, Azharul Islam. Emerging Immunomodulation Technologies May Potential Improve the Clinical and Pharmaceutical Health Care. Int
6. Taha Nazir. COVID-19: Reliable scientific knowledge amid uncertain and complex informat