Endocrinology, Endocrinology, Diabetes and Metabolism, Behavioral Neuroscience
81
Scopus Publications
Scopus Publications
Preoperative assessment of sarcopenia and osteosarcopenia prevalence in bariatric surgery candidates over 60 J. Molero, J. Vidal, J.R. Mendoza, S. Cañizares, M. Caballero, S. Logwin, A. Pané, A. de Hollanda, L. Flores Clinical Nutrition Espen, 2026 BACKGROUND: The prevalence of obesity in adults over 60 is rising, presenting challenges for healthcare systems. Bariatric surgery (BS) is increasingly considered for older adults, but complex health risk such as sarcopenic obesity (SO) and osteosarcopenic obesity (OSO) need evaluation to optimize clinical outcomes and guide preoperative risk stratification. OBJECTIVES: The aims was to describe the prevalence and severity of SO, OSO, and to examine the associated health consequences in BS candidates over 60 years. SETTING: This prospective cross-sectional study was conducted at a single tertiary care university hospital. METHODS: Cross-sectional study of 109 BS candidates over 60 years. The assessments included anthropometry, body composition (BC), muscle strength and function, bone mineral density (BMD), physical activity (PA) levels and metabolic pathologies associated with obesity. SO and OSO were defined using ESPEN/EASO (2022) consensus criteria. RESULTS: The mean age of the participants was 64.1 (2.9), and, 36 % were male. The prevalence of SO was 42 %, with no significant differences between sexes. This prevalence was primarily due to greater impairment in the 5-times sit-to-stand test (39.8 %). The prevalence of OSO was 26.8 %, largely attributed to a higher prevalence of osteopenia in females. Among obesity-related pathologies, only obstructive sleep apnea was more prevalent in males. Those with SO had a lower BMD and PA levels. CONCLUSIONS: The high prevalence of SO and OSO in BS candidates over 60 highlights the importance of comprehensive preoperative assessment. Sex and age-specific differences in BC and sarcopenia severity underscore the need for tailored interventions.
Awareness of obesity’s causes is not linked to less Weight-Related bias Albert Lecube, Rodolfo J. Galindo, Blanca Salinas-Roca, Iñaki Marina, Andreea Ciudin, Ana Belén Crujeiras, Cristóbal Morales, Sharona Azriel, Rafael Gómez-Blasco, César Bustos, Javier Butragueño, Lilliam Flores, Guillermo E. Umpierrez, María M Malagón Scientific Reports, 2025 Weight stigma remains a major public health issue that negatively impacts individuals living with obesity. This study explores its prevalence in the Spanish adult population and examines whether viewing obesity as a disease influences societal attitudes. A representative sample of 1,000 adults participated in a Computer-Assisted Telephone Interview assessing knowledge, stereotypes, prejudice, and discrimination related to obesity, along with sociodemographic data and personal beliefs about its causes. While 40.8% attributed obesity to a lack of self-control, 59.2% considered it a disease. Those in the latter group were more likely to recognize its multifactorial causes and support public funding for treatment. However, weight bias remained prevalent across both perspectives, with no significant differences in discriminatory attitudes. Around 30% of participants admitted to holding negative stereotypes or engaging in weight-based discrimination. These findings suggest that simply framing obesity as a disease does not meaningfully reduce weight stigma. Broader efforts are needed-beyond education alone-to challenge societal narratives and address structural contributors to bias, ultimately fostering a more supportive and inclusive environment for individuals affected by obesity.
Promoting a turnaround in the management of renal disease in obese patients Albert Lecube, Jorge Iván Zamora, Sharona Azriel, Esther Barreiro, Guadalupe Blay, Juana Carretero-Gómez, Andreea Ciudin, José Manuel Fernández-García, Lilliam Flores, Ana de Hollanda, Marina López-Martínez, Eva Martínez, Inka Miñambres, Violeta Moizé, Cristóbal Morales, Violeta Ramírez, Javier Salvador, Marta Supervía, Víctor Valentí, Germán Vicente-Rodríguez, Nuria Vilarrasa, María M. Malagón, María José Soler Nefrologia, 2025 Lecube, Albert; Zamora, Jorge Iván; Azriel, Sharona; Barreiro, Esther; Blay, Guadalupe; Carretero-Gómez, Juana; Ciudin, Andreea; Fernández-García, José Manuel; Flores, Lilliam; de Hollanda, Ana; López-Martínez, Marina; Martínez, Eva; Miñambres, Inka; Moizé, Violeta; Morales, Cristóbal; Ramírez, Violeta; Salvador, Javier; Supervía, Marta; Valentí, Víctor; Vicente-Rodríguez, Germán; Vilarrasa, Nuria; Malagón, María M.; Soler, María José
Alcohol and Other Substance Screening in Bariatric Surgery Candidates: Utility of Self-Report and Toxicology Tests, Including Ethyl-Glucoronide Silvia Cañizares, Laura Nuño, Pablo Barrio, Mireia Forner-Puntonet, Carolina Gavotti, Miquel Monràs, Patricia Gavín, Ricard Navinés, Lilliam Flores, Maite Barrios, Alba Andreu, Judit Molero, Amanda Jimenez, Josep Vidal, Anna Lligoña Obesity Surgery, 2025 Following bariatric surgery (BS) patients have an increased risk of alcohol misuse. Purpose This 1-year cross-sectional study in potential BS candidates had several objectives: (a) assess the prevalence of risky drinking, alcohol use disorder (AUD), and other substance use/disorder; (b) compare the prevalence of these behaviors to that of the general Spanish population; (c) determine the proportion of patients with positive results in toxicology tests; and (d) study the predictive factors of risky drinking. Setting: tertiary university hospital. Materials and Methods Alcohol and other substance use were evaluated with the AUDIT-C and ASSIST questionnaires. Urine tests analyzed several markers (ethyl-glucoronide [EtG] ≥ 500 ng/ml, amphetamine, benzodiazepine, cannabinoid, cocaine, and opioid). The Mini-International-Neuropsychiatric-Interview (5.0.0) was employed to assess psychiatric diagnoses. Results Among 308 candidates for BS, 196 were accepted to participate (69% women; mean age 46.7 ± 10.9 years; mean body mass index 45.6 ± 5.9). AUDIT-C and ASSIST identified 7% and 5% of risky drinkers, respectively. Men were more frequently risky drinkers compared to women (18% vs. 2%) and compared to the general population (18% vs. 8%). Six percent of individuals had AUD, being men the most affected, and 2% met criteria for other substance disorder. Fifteen percent of the sample presented risky tobacco use. Cannabis was self-reported only by males (3%). EtG ≥ 500 ng/ml was present in 15% of the sample, being a risk factor for risky drinking together with the male sex. Conclusion Identification of candidates at risk for risky drinking can help to prevent any alcohol misuse after BS. The combination of subjective and objective measures improves the validity of the assessment of substance use. Graphical Abstract
The Spanish GIRO Guideline: A Paradigm Shift in the Management of Obesity in Adults Albert Lecube, Sharona Azriel, Esther Barreiro, Guadalupe Blay, Juana Carretero-Gómez, Andreea Ciudin, José Manuel Fernández, Lilliam Flores, Ana de Hollanda, Eva Martínez, Inka Miñambres, Violeta Moizé, Cristóbal Morales, Violeta Ramírez, Javier Salvador, María José Soler, Marta Supervía, Víctor Valentí, Germán Vicente-Rodríguez, Nuria Vilarrasa, María M. Malagón Obesity Facts, 2025
Bariatric Surgery Outcomes in Patients with Chronic Kidney Disease Adriana Pané, Maria Claro, Alicia Molina-Andujar, Romina Olbeyra, Bárbara Romano-Andrioni, Laura Boswell, Enrique Montagud-Marrahi, Amanda Jiménez, Ainitze Ibarzabal, Judith Viaplana, Pedro Ventura-Aguiar, Antonio J. Amor, Josep Vidal, Lilliam Flores, Ana de Hollanda Journal of Clinical Medicine, 2023
Obesity and fertility. Position statement I. Miñambres, A. de Hollanda, N. Vilarrasa, S. Pellitero, M.A. Rubio, L. Flores, A. Caixàs, S. Lobo, J.I. Martinez Salamanca, B. Acevedo, V. Moizé, A. Andreu, J. Escalada Endocrinologia Diabetes Y Nutricion, 2023
Bariatric Surgery Outcomes in Patients with Kidney Transplantation Adriana Pané, Alicia Molina-Andujar, Romina Olbeyra, Bárbara Romano-Andrioni, Laura Boswell, Enrique Montagud-Marrahi, Amanda Jiménez, Ainitze Ibarzabal, Judith Viaplana, Pedro Ventura-Aguiar, Antonio J. Amor, Josep Vidal, Lilliam Flores, Ana de Hollanda Journal of Clinical Medicine, 2022
Prevalence of low skeletal muscle mass following bariatric surgery Judith Molero, Romina Olbeyra, Lilliam Flores, Amanda Jiménez, Ana de Hollanda, Alba Andreu, Ainitze Ibarzabal, Violeta Moizé, Sílvia Cañizares, José María Balibrea, Amadeu Obach, Josep Vidal Clinical Nutrition Espen, 2022
Duodenal-Jejunal Bypass Liner for the management of Type 2 Diabetes Mellitus and Obesity: A Multicenter Randomized Controlled Trial Aruchuna Ruban, Alexander D. Miras, Michael A. Glaysher, Anthony P. Goldstone, Christina G. Prechtl, Nicholas Johnson, Navpreet Chhina, Werd Al-Najim, Madhawi Aldhwayan, Natalia Klimowska-Nassar, Claire Smith, Joanne Lord, Jia V. Li, Lilliam Flores, Moaz Al-Lababidi, Georgios K. Dimitriadis, Mayank Patel, Michael Moore, Harvinder Chahal, Ahmed R. Ahmed, Jonathan Cousins, Ghadah Aldubaikhi, Ben Glover, Emanuela Falaschetti, Hutan Ashrafian, Carel W. le Roux, Ara Darzi, James P. Byrne, Julian P. Teare Annals of Surgery, 2022
The SEEN comprehensive clinical survey of adult obesity: Executive summary María D. Ballesteros Pomar, Nuria Vilarrasa García, Miguel Ángel Rubio Herrera, María José Barahona, Marta Bueno, Assumpta Caixàs, Alfonso Calañas Continente, Andreea Ciudin, Fernando Cordido, Ana de Hollanda, María Jesús Diaz, Lilliam Flores, Pedro Pablo García Luna, Fernando García Pérez-Sevillano, Albert Goday, Albert Lecube, Juan José López Gómez, Inka Miñambres, María José Morales Gorria, Rosa Morinigo, Joana Nicolau, Silvia Pellitero, Javier Salvador, Sergio Valdés, Irene Bretón Lesmes Endocrinologia Diabetes Y Nutricion, 2021
New metrics to assess type 2 diabetes after bariatric surgery: The “time-within-remission range” Ana de Hollanda, Albert Lecube, Miguel Angel Rubio, Enric Sánchez, Núria Vilarrasa, José Gregorio Oliva, María Luisa Fernández-Soto, Jordi Salas-Salvadó, María D. Ballesteros-Pomar, Andreea Ciudin, Ferran Torres, Concepción Vidal, María José Morales, Sergio Valdés, Silvia Pellitero, Inka Miñambres, Lluís Masmiquel, Albert Goday, Lorena Suarez, Liliam Flores, Marta Bueno, Assumpta Caixàs, Irene Bretón, Rosa Cámara, Romina Olbeyra, Rona Penso, María José de la Cruz, Andreu Simó-Servat, Francisca María Pereyra-García, Elena Teresa López-Mezquita, Anna Gils, Enzamaria Fidilio, Orosia Bandrés, Ángel Martínez, Jose Abuín, Montserrat Marques-Pamies, Laura Tuneu, Magdalena Arteaga, Olga Castañer, Fernando Goñi, Cristina Arrizabalaga, Manuel Antonio Botana, Alfonso Calañas, Ángel Rebollo Journal of Clinical Medicine, 2020
