Development and Validation of Quality by Design assisted RP-HPLC Method for Estimation of Ellagic acid and its Application to Plant Extract Abhishek C. Teli, Mrityunjaya B. Patil, Ashwini M. Chougla, Sachin P. Gudasi, Akshay K. Patil Research Journal of Pharmacy and Technology, 2026 This study aims to develop and validate RP-HPLC method for the estimation of ellagic acid in Acalypha indica extract. The isocratic RP-HPLC method was developed using a C18 column with a mobile phase consisting of methanol and 0.1% orthophosphoric acid (75:25 v/v), operated at a flow rate of 0.9 mL/min. A central composite design was employed for method optimization considering mobile phase composition and flow rate as critical process parameters and retention time and plate count were chosen as the critical analytical attributes. The method was validated for analytical parameters such as linearity, precision, accuracy, specificity, selectivity and the limits of detection (LOD) and quantification (LOQ). The optimized run was validated as per ICH guidelines. A strong linear relationship (R² = 0.9984) was established within the concentration range of 5–25 µg/mL. The method demonstrated excellent reproducibility and recovery evident by %RSD value which was less than 2. The LOD and LOQ were determined to be 0.141 µg/mL and 0.430 µg/mL, respectively. The method exhibited precise, accurate, robust and rugged characteristics as shown by % RSD values which were less than 2. The measured concentration of EA in Acalypha indica L. extracts were found to be 5.5034 µg/mL. The validated RP-HPLC method is sensitive, precise, accurate and robust, making it an effective tool for the reliable quantification of EA in Acalypha indica L. extracts. Hence, it can be concluded that developed method can be used for EA analysis in plant extract as part of quality standardization.
Exploring the anti-obesity potential of Ailanthus excelsa Roxb in vitro enzymatic inhibition and computational pharmacology insights Sachin Gudasi, M. B. Patil, Shankar Gharge, Shriram D. Ranade, Hannah Lalengzuali Fanai, Jagdish Chand, Sheikh F. Ahmad, Sabry M. Attia, Talha Bin Emran Scientific Reports, 2025 This study explores the potential of Ailanthus excelsa Roxb. for managing obesity by evaluating its effects on key metabolic enzymes. We evaluated a hydroalcoholic extract and its fractions for their ability to modulate important metabolic enzymes, porcine pancreatic lipase , HMG-CoA reductase , α-glucosidase , and α-amylase activities. Our methodology integrated in vitro enzymatic assays with cluster analysis (MCODE, ClueGO, and Cluepedia) and network pharmacology to elucidate interactions between metabolites and target enzymes. Protein-protein interaction (PPI) analysis, consisting of a network with 51 nodes and 264 edges, was performed using the CytoNCA plugin to calculate topological parameters. Key targets were identified based on degree centrality, including ADIPOQ , PPARA , PPARG , IL6 , TNF , and AKT1 . Cluster analysis of the PPI networks, conducted using the MCODE plugin, highlighted a top cluster with a high score of 22.82. Network pharmacology has identified key targets associated with obesity, including HK1 , HK2 , PIK3CA , AKT1 , MTOR , CD36 , ACACB , SLC2A4 , CPTIA , INSR , ACACA , FASN , and ADIPOQ . These targets are linked to highly modulated metabolic pathways. Isoquercetin shows significant binding affinities: − 7.11 for HMG-CoA Reductase (PDB ID: 1HW9), -9.96 for lipase (PDB ID: 1LPB), − 8.96 for α-amylase , and − 10.41 for α-Glucosidase (PDB ID: 3A47). The ethyl acetate fractions exhibit notable inhibition of Porcine Pancreatic lipase (IC 50 : 56.25 ± 4.85 µg/mL) and HMG-CoA reductase (IC 50 : 108.27 ± 3.38 µg/mL), α-glucosidase (IC 50 : 117.08 ± 3.28 µg/mL), and α-amylase (IC 50 : 125.93 ± 2.29 µg/mL). Moreover, metabolites showed stronger binding affinities to all four enzymes than reference molecules. By integrating in vitro assays with molecular modeling , this study highlights the promising potential of A. excelsa and its fractions in obesity management, offering valuable insights into its therapeutic applications.
UPLC-MS/MS and Box–Behnken Design Optimization of Ultrasound-Assisted Extraction of Ailanthus excelsa with Pharmacophore Modeling and Molecular Docking Studies Targeting HMG-CoA Reductase Sachin Gudasi, M. B. Patil, Shankar Gharge, Rahul Koli, N. A. Khatib Chemistryselect, 2025 Ailanthus excelsa is a medicinal plant known for its diverse pharmacological properties. Optimizing extraction methods is crucial for enhancing the yield of bioactive compounds, ensuring efficiency and sustainability. This study investigates the optimal extraction conditions of A. excelsa , along with UPLC‐MS/MS analysis, and in silico evaluation against HMG‐CoA reductase. Ultrasound‐assisted extraction parameters were optimized using Box–Behnken design, yielding optimal conditions at 60 °C for 30 min and a solid‐to‐solvent ratio of 1:15. Under these conditions, the extract showed a pancreatic lipase inhibition IC 50 value of 110.7 µg/mL, total phenolic content of 23.4 mg GAE/g, and total flavonoid content of 32.6 mg QE/g. The optimized extract (Batch 14) exhibited notable in vitro inhibitory activity against HMG‐CoA reductase (IC 50 = 50.21 µg/mL). UPLC‐MS/MS analysis identified 35 phytoconstituents. Receptor‐based e‐pharmacophore modeling, based on simvastatin (HMG‐CoA reductase) interactions, facilitated virtual screening, identifying S9, S12, and S19 as top candidates. Molecular docking studies against HMG‐CoA reductase (PDB ID: 1HW9) revealed that S13, S12, and S9 exhibited superior binding affinities (−5.08, −5.03, and − 4.07, respectively) compared to simvastatin (−1.98), forming key interactions with GLU559, SER565, and ARG568. These findings highlight A. excelsa as a promising source of HMG‐CoA reductase inhibitors with potential application in metabolic disorder management.
Network pharmacology-based toxicity, molecular docking, and molecular dynamics analysis of phytoconstituents from roots of Nerium indicum L Veerkumar P. Japti, Mrityunjaya B. Patil, Banappa S. Unger, Shamanand P. Mallapur, Akshay Shamnewadi, Vishal S. Patil, Sathgowda Patil, Anand V. Desai Pharmacological Research Modern Chinese Medicine, 2025 • Oleandrin and odoroside A exhibit high systemic and organ-specific toxicity • Targets PTGS2 and MAPK1 disrupt inflammation and survival signaling pathways • Docking shows strong binding of oleandrin to cardiotoxicity-related proteins • GO analysis links compounds to oxidative stress and neuroinflammation • Supports detox strategies for safer therapeutic use of Nerium indicum Herbal medicine plays a vital role in healthcare, but safety concerns arise due to potential toxicity risks. Nerium indicum (夹竹桃, jiā zhú táo) is used in Chinese herbal medicine for its therapeutic effects, yet it contains toxic cardiac glycosides. This study investigates its toxicity mechanisms using systems biology tools to support safer applications through comprehensive risk-benefit evaluation and detoxification strategies. Computational analyses were performed to predict drug-likeness, toxicity, LD₅₀, and blood-brain barrier (BBB) penetration. Key toxicity-related genes were identified using SwissTargetPrediction and GeneCards. Gene Ontology (GO) and pathway enrichment analyses further explored toxicity mechanisms, while molecular docking and dynamics simulations assessed interactions between core targets, Prostaglandin-endoperoxide synthase 2 (PTGS2) and Mitogen-Activated Protein Kinase 1 (MAPK1), offering deeper insights into toxicity modulation. Computational analyses identified oleandrin, and odoroside A as highly toxic, with significant cardiotoxic and hepatotoxic risks. Network analysis revealed PTGS2 and MAPK1 as key toxicity regulators, mediating pathways linked to inflammation and cellular stress. Molecular docking showed Oleandrin exhibiting the strongest binding affinities with PTGS2 (-8.5 kcal/mol) and MAPK1 (-9.2 kcal/mol), while molecular dynamics simulations confirmed its stable interactions, suggesting a critical role in toxicity modulation. This study highlights Oleandrin and related compounds as major toxicity contributors in Nerium indicum, emphasizing their impact on cardiac, hepatic, and neurological pathways. The findings underscore the need for cautious therapeutic use and potential detoxification strategies for safer applications.
Comprehensive review on anti-obesity effects of plant-derived compounds: Evidence from 3T3-L1 adipocytes and high-fat diet models Sachin Gudasi, Mrityunjaya B. Patil Aspects of Molecular Medicine, 2025 Obesity, a multifactorial chronic disease, poses a growing global health concern, contributing to increased incidences of type 2 diabetes, cardiovascular diseases, osteoarthritis, and several cancers. Despite various pharmacological attempts targeting lipid metabolism enzymes, the associated adverse effects have led to numerous drug withdrawals, underscoring the urgent need for safer and more effective therapeutic strategies. In this context, the present study explores the novel therapeutic potential of plant-derived bioactives, specifically formulated using gold nanoparticles (GNPs), for the management of obesity. We systematically investigated the modulation of critical adipogenic and lipogenic regulatory proteins—C/EBP-α, PPAR-α, perilipin-1, adiponectin, FABP4, FAS, and ACC in 3T3-L1 pre-adipocytes and high-fat diet-induced obese mice. Our findings demonstrate that GNP-encapsulated phytoconstituents significantly reduce intracellular lipid accumulation by activating AMPK, a key energy sensor that downregulates pro-adipogenic and lipogenic genes (PPAR-α, C/EBP-α, AP2, SREBP-1c, ACC1, FAS, and LPL), while concurrently upregulating lipolytic and thermogenic genes (HSL, PGC-1α, and SIRT1) and enhancing adiponectin expression. The novelty of this study lies in the synergistic application of nanotechnology and traditional plant-based therapeutics to target obesity at a molecular level, offering a dual advantage of enhanced bioavailability and targeted action. These outcomes provide compelling evidence for the use of functionalized nanoparticles as a next-generation anti-obesity strategy, with potential translational value for clinical application.
Development of a robust HPTLC method for estimation of β-carotene in nano-formulated apricot extract Manisha Rajpurohit, Mrityunjaya Patil, Nayeem Khatib Journal of Applied Pharmaceutical Science, 2025 Fruits play a crucial role in our fight against diseases and disorders. Apricots are temperate fruits classified under the Rosaceae family. Fruits are rich in carotenoids, phenolic compounds, and flavonoids which contribute to color, taste, and nutritional value. Currently, no standardized high-performance thin-layer chromatography (HPTLC) method exists for analyzing apricots. This study aimed to develop and validate a sensitive, specific, economical, reliable, and precise HPTLC method for quantifying β-carotene in apricot extract and its nano-formulation. Apricot nano-formulation was prepared, characterized, and quantified. In this method, a silica gel aluminum TLC plate was used as the stationary phase, and toluene: acetone in a ratio of 7:3v/v was used as the mobile phase. Analysis was performed at wavelength 448 nm. To ensure method reliability, validation was performed according to ICH guidelines. Prepared nano-formulation showed particle size 101.7 ± 0.12 nm, polydispersity index of 0.125, entrapment efficiency % of 78.6%, zeta potential −25mV, and transmission electron microscopy analysis revealed vesicles are smooth spherical in shape. Regression analysis demonstrated a good linear relationship (R² = 0.9935) within a 100–500 ng/band concentration range. The LOD and LOQ were found to be 22.05 ng/band and 66.82 ng/band, respectively. The validated HPTLC method was successfully applied for quantification of β-carotene in apricot nano-formulation. Hence, the developed HPTLC method would be an important tool in utilizing the quality control methods for herbal formulations.
Hypolipidemic activity and HPTLC analysis of Ixora coccinea L. Leaves Journal of Applied Pharmaceutical Science, 2011
Antihyperlipidemic activity of Nerium indicum leaves extracts in hyperlipidemic rats Plant Archives, 2011
Preparation and evaluation of antidiabetic polyherbal formulation Indian Drugs, 2010
Wound healing activity of roots of Asparagus racemosus willd Indian Drugs, 2010
Evaluation of anti-inflammatory activity of ethanolic extract of Borassus flabellifer L. male flowers (inflorescences) in experimental animals Journal of Medicinal Plants Research, 2009
Development and characterization of melt-in-mouth tablets of haloperidol by sublimation technique International Journal of Pharmacy and Pharmaceutical Sciences, 2009
Evaluation of disintegrating properties of Abelmoschus esculentus mucilage International Journal of Pharmtech Research, 2009
Polysaccharides based colon specific drug delivery: A review International Journal of Pharmtech Research, 2009
Design and in vitro evaluation of oral floating matrix tablets of aceclofenac International Journal of Chemtech Research, 2009
Development and characterization of orodispersible tablets of aceclofenac by sublimation technique International Journal of Pharmtech Research, 2009
Formulation evaluation of mouth dissolving tablets of fenofibrate using sublimation technique International Journal of Chemtech Research, 2009
Preliminary phytochemical investigation and wound healing activity of Allium cepa linn (Liliaceae) International Journal of Pharmacy and Pharmaceutical Sciences, 2009
Isolation and evaluation of disintegrant properties of fenugreek seed mucilage International Journal of Pharmtech Research, 2009
Evaluation of the analgesic and antipyretic activities of ethanolic extract of male flowers (inflorescences) of Borassus Flabellifer L. (arecaceae) International Journal of Pharmacy and Pharmaceutical Sciences, 2009
Enhancement of dissolution rate of aceclofenac by solid dispersion technique International Journal of Pharmtech Research, 2009
Pharmacognostical, phytochemical screening and acute toxicity study of Crateva nurvala stem bark Pharmacognosy Journal, 2009
Wound healing activity of Hyptis suaveolens (L.) Poit (Lamiaceae) International Journal of Pharmtech Research, 2009
Evaluation of Anacardium occidentale gum as gelling agent in aceclofenac gel International Journal of Pharmtech Research, 2009
Influence of ethanolic extract of Borassus flabellifer L. male flowers (inflorescences) on chemically induced acute-inflammation and poly arthritis in rats International Journal of Pharmtech Research, 2009
Formulation and evaluation of effervescent floating tablet of famotidine International Journal of Pharmtech Research, 2009
Evaluation of aqueous extract of leaves of Ocimum kilimandscharicum on wound healing activity in albino wistar rats International Journal of Pharmtech Research, 2009
Isolation and evaluation of disintegrating properties of Salicornia fruticosa (L.) mucilage International Journal of Pharmtech Research, 2009
Evaluation of Abelmoschus esculentus mucilage as suspending agent in paracetamol suspension International Journal of Pharmtech Research, 2009
Taste masked ofloxacin mouth disintegrating tablets Indian Drugs, 2005
Development and evaluation of ocular films of cromolyn sodium Indian Journal of Pharmaceutical Sciences, 2004
Microencapsulation of verapamil hydrochloride by ionotropic gelation technique Indian Journal of Pharmaceutical Sciences, 2004
Wound healing activity of the roots of Eclipta alba Linn. Indian Drugs, 2004
Antiinflammatory activity of the leaves of Anacardium occidentale linn Indian Journal of Pharmaceutical Sciences, 2003
Hepatoprotective activity of the fruits of Piper longum Linn Indian Journal of Pharmaceutical Sciences, 2003
Effect of Lawsonia alba leaf extracts on carbon tetrachloride-induced hepatic damage in albino rats Journal of Natural Remedies, 2003
Analgesic and antipyretic activity of Pergularia extensa in rats Indian Journal of Pharmaceutical Sciences, 2002
Wound healing activity of the galls of Quercus infectoria olivier Journal of Natural Remedies, 2002
Wound healing property of Eucalyptus globulus L. leaf extract' Indian Drugs, 2002
Preliminary phytochemical investigation and wound healing activity of the leaves of Argemone mexicana linn. (papaveraceae) Indian Drugs, 2001
RECENT SCHOLAR PUBLICATIONS
Exploring the Therapeutic Potential of Apricot-Loaded Phytosomal Gel for Burn Wound Healing in Wistar Rats M Rajpurohit, M Patil, N Khatib Journal of Pharmaceutical Innovation 20 (6), 220 , 2025 2025
Ailanthus excelsa ’s lipid-modulating potential through PPAR and PI3K-Akt pathways: insights from system biology approach and 3T3-L1 adipocyte studies S Gudasi, MB Patil, S Gharge, NA Khatib Network Modeling Analysis in Health Informatics and Bioinformatics 14 (1), 131 , 2025 2025 Citations: 1
Optimization of ultrasound-assisted extraction of Acalypha indica using box-behnken design: Network pharmacology, molecular docking, and evaluation of … MB Patil, A Teli, S Gudasi, A Patil Analytical Chemistry Letters 15 (6), 964-983 , 2025 2025
Development and validation of a green high-performance thin-layer chromatography method for β-sitosterol: application to Ailanthus excelsa phytosomes and … S Gudasi, MB Patil, R Koli, S Gharge JPC–Journal of Planar Chromatography–Modern TLC, 1-15 , 2025 2025 Citations: 1
UPLC‐MS/MS and Box–Behnken Design Optimization of Ultrasound‐Assisted Extraction of Ailanthus excelsa with Pharmacophore Modeling and Molecular … S Gudasi, MB Patil, S Gharge, R Koli, NA Khatib ChemistrySelect 10 (38), e01920 , 2025 2025 Citations: 1
Exploring the anti-obesity potential of Ailanthus excelsa Roxb in vitro enzymatic inhibition and computational pharmacology insights S Gudasi, MB Patil, S Gharge, SD Ranade, HL Fanai, J Chand, SF Ahmad, ... Scientific Reports 15 (1), 32747 , 2025 2025 Citations: 4
Network pharmacology-based toxicity, molecular docking, and molecular dynamics analysis of phytoconstituents from roots of Nerium indicum L VP Japti, MB Patil, BS Unger, SP Mallapur, A Shamnewadi, VS Patil, ... Pharmacological Research-Modern Chinese Medicine 16, 100640 , 2025 2025 Citations: 4
Comprehensive review on anti-obesity effects of plant-derived compounds: evidence from 3T3-L1 adipocytes and high-fat diet models S Gudasi, MB Patil Aspects of Molecular Medicine 5, 100089 , 2025 2025 Citations: 7
A Synergistic Approach to Diabetes Management: A Comprehensive Review of a Novel Polyherbal Formulation Comprising Moringa Oleifera, Trigonella Foenum-graecum, and Berberis … A Jakkannavar, S Patil, S Jalalpure KLE Journal of Pharmaceutical and Health Sciences Research 1 (1), 1-19 , 2025 2025
Development of a robust HPTLC method for estimation of β-carotene in nano-formulated apricot extract M Rajpurohit, M Patil, N Khatib Journal of Applied Pharmaceutical Science 15 (3), 270-279 , 2025 2025 Citations: 2
Pongamia pinnata: A Comprehensive Review of its Pharmacognostical Studies and Pharmacological Activities A Jakkannavar, S Patil, M Patil, S Jalalpure, A Patil Research Journal of Pharmacy and Technology 18 (8), 3953-3960 , 2025 2025 Citations: 1
A Comprehensive Review on Acalypha indica: Traditional uses and pharmacological properties AC Teli, MB Patil, AK Patil Int. J. Pharmacogn 12 (3), 154-168 , 2025 2025 Citations: 2
Pharmacovigilance for herbal medicines A Jakkannavar, S Patil, M Patil, S Suryawanshi Asian Journal of Research in Pharmaceutical Sciences 14 (4), 407-417 , 2024 2024
Simultaneous determination of gallic acid, berberine and trigonelline in polyherbal churna by HPTLC method S Patil, P Khushwah, S Gudasi, M Patil, M Kunchanur, R Koli Journal of Young Pharmacists 16 (2), 261 , 2024 2024 Citations: 8
Polymer-based hydrogels as enhanced drug delivery system A Jakkannavar, S Patil, M Patil Asian Journal of Research in Chemistry 17 (6), 392-398 , 2024 2024 Citations: 2
Commissioning of the MACE gamma-ray telescope at Hanle, Ladakh, India. KK Yadav, N Chouhan, R Thubstan, S Norlha, J Hariharan, C Borwankar, ... Current Science (00113891) 123 (12) , 2022 2022 Citations: 11
Gene ontology enrichment analysis of PPAR-γ modulators from Cassia glauca in diabetes mellitus SG Ternikar, MB Patil, I Pasha, PSR Dwivedi Journal of Diabetes & Metabolic Disorders 20 (2), 1239-1246 , 2021 2021 Citations: 4
Poly-herbal tablet formulation by design expert tool and in vitro anti-lipase activity A Balekundri, A Shahapuri, M Patil Future Journal of Pharmaceutical Sciences 6 (1), 125 , 2020 2020 Citations: 16
Gene set enrichment analysis of α-amylase and α-glucosidase inhibitors of Cassia glauca SG Ternikar, MB Patil, I Pasha, P Khanal Journal of Diabetes & Metabolic Disorders 19 (2), 683-689 , 2020 2020 Citations: 10
In vitro antioxidant and anti-hepatotoxic activities of roots of Potentilla fulgens Wall: an ethno medicinal plant of North Eastern India T Uriah, M Patil, S Kummara Indian Journal of Natural Products 33 (1) , 2019 2019 Citations: 2
MOST CITED SCHOLAR PUBLICATIONS
Synthesis, characterization, biocompatible and anticancer activity of green and chemically synthesized silver nanoparticles–a comparative study S Kummara, MB Patil, T Uriah Biomedicine & Pharmacotherapy 84, 10-21 , 2016 2016 Citations: 207
Evaluation of Abelmoschus esculentus mucilage as suspending agent in paracetamol suspension R Kumar, MB Patil, SR Patil, MS Paschapur International Journal of PharmTech Research 1 (3), 658-665 , 2009 2009 Citations: 193
Preliminary phytochemical investigation and wound healing activity of Allium cepa Linn (Liliaceae) C Shenoy, MB Patil, R Kumar, S Patil International journal of pharmacy and pharmaceutical sciences 2 (2), 167-175 , 2009 2009 Citations: 157
Antimicrobial and wound healing activities of leaves of Alternanthera sessilis Linn SS Jalalpure, N Agrawal, MB Patil, R Chimkode, A Tripathi International Journal of Green Pharmacy (IJGP) 2 (3) , 2008 2008 Citations: 156
Green and ecofriendly synthesis of silver nanoparticles: characterization, biocompatibility studies and gel formulation for treatment of infections in burns K Jadhav, D Dhamecha, D Bhattacharya, M Patil Journal of Photochemistry and Photobiology B: Biology 155, 109-115 , 2016 2016 Citations: 148
Formulation and evaluation of ondansetron hydrochloride directly compressed mouth disintegrating tablets SA Sreenivas, AP Gadad, PM Dandagi, VS Mastiholimath, MB Patil INDIAN DRUGS-BOMBAY- 43 (1), 35 , 2006 2006 Citations: 137
Hepatoprotective activity of the fruits of Piper longum Linn SS Jalalpure, MB Patil, NS Prakash, K Hemalata, FV Manvi Indian journal of pharmaceutical sciences 65 (4), 363-366 , 2003 2003 Citations: 130
Isolation and evaluation of disintegrant properties of fenugreek seed mucilage R Kumar, S Patil, MB Patil, SR Patil, MS Paschapur International Journal of PharmTech Research 1 (4), 982-996 , 2009 2009 Citations: 129
Evaluation of anti-inflammatory activity of ethanolic extract of Borassus flabellifer L. male flowers (inflorescences) in experimental animals MS Paschapur, MB Patil, R Kumar, SR Patil Journal of Medicinal Plants Research 3 (2), 049-054 , 2009 2009 Citations: 117
Antidiabetic activity of Pongamia pinnata leaf extracts in alloxan-induced diabetic rats MS Sikarwar, MB Patil International journal of Ayurveda research 1 (4), 199 , 2010 2010 Citations: 100
Antihyperlipidemic activity of Salacia chinensis root extracts in triton-induced and atherogenic diet-induced hyperlipidemic rats MS Sikarwar, MB Patil Indian journal of pharmacology 44 (1), 88-92 , 2012 2012 Citations: 94
Evaluation of Anacardium occidentale gum as gelling agent in aceclofenac gel R Kumar, MB Patil, SR Patil, MS Paschapur International Journal of PharmTech Research 1 (3), 695-704 , 2009 2009 Citations: 93
Formulation and evaluation of effervescent floating tablet of famotidine R Kumar, MB Patil, SR Patil, MS Paschapur Int J Pharm Tech Res 1 (3), 754-763 , 2009 2009 Citations: 92
Development and evaluation of hepatoprotective polyherbal formulation containing some indigenous medicinal plants PM Dandagi, MB Patil, VS Mastiholimath, AP Gadad, RH Dhumansure Indian journal of pharmaceutical sciences 70 (2), 265 , 2008 2008 Citations: 90
Antidiabetic activity of Crateva nurvala stem bark extracts in alloxan-induced diabetic rats MS Sikarwar, MB Patil Journal of pharmacy and bioallied sciences 2 (1), 18-21 , 2010 2010 Citations: 84
Preliminary phytochemical investigation and wound healing activity of the leaves of Argemone mexicana Linn.(Papaveraceae) MB Patil, SS Jalalpure, A Ashraf INDIAN DRUGS-BOMBAY- 38 (6), 288-293 , 2001 2001 Citations: 80
Evaluation of the analgesic and antipyretic activities of ethanolic extract of male flowers (inflorescences) of Borassus flabellifer L.(Arecaceae) MS Paschapur, S Patil, SR Patil, R Kumar, MB Patil International journal of pharmacy and pharmaceutical sciences 1 (2), 98-106 , 2009 2009 Citations: 79
Antiulcer properties of alcoholic extract of Cynodon dactylon in rats MB Patil, SS Jalalpure, NS Prakash, CK Kokate III WOCMAP Congress on Medicinal and Aromatic Plants-Volume 6: Traditional … , 2003 2003 Citations: 76
Formulation evaluation of mouth dissolving tablets of fenofibrate using sublimation technique R Kumar, S Patil, MB Patil, SR Patil, MS Paschapur Int J Chem Tech Res 1 (4), 840-850 , 2009 2009 Citations: 75
Antidiabetic activity of insulin plant (Costus igneus) leaf extract in diabetic rats V Bhat, N Asuti, A Kamat, MS Sikarwar, MB Patil J Pharm Res 3 (3), 608-611 , 2010 2010 Citations: 71
