Dr. Rakkimuthu Ramalingam

@ngmc.org

Assistant Professor of Botany
Nallamuthu Gounder mahalingam College

RESEARCH INTERESTS

Phytochemistry, Plant tissue culture, Microbiology
6

Scopus Publications

128

Scholar Citations

7

Scholar h-index

5

Scholar i10-index

Scopus Publications

  • Floristic Diversity and Ethnobotanical Studies of Nandha Gopalasamy Hill Temple Sacred Grove of Western Ghats, Pollachi Taluk, Coimbatore
    A.M. Ananda Kumar, D. Rathika, R. Rakkimuthu, P. Sathishkumar
    Agricultural Science Digest, 2023
    Background: The sacred groves are considered to be ecologically most important area as they are rich in plant diversity. It is considered to be repository of many important medicinal plantspecies including endangered and endemic and many valuable plant species. An ethanobotanical survey was carried out to assess the floristic diversity and it medicinal properties used by the indigenous peoples and local people. The floristic study conducted to understand the status of vegetation an it is important step towards conservation. Methods: The study was carried out for about one yearby frequent field visit and inperson interview with indigenous peoples to know the medicinal properties of the species. Result: The study showed presence of 54 medicinal plants out of which 22 are herbs, 12 shrubs, 2 climbers and 17 are tree habits. All the plants are found to be highly medicinal in treating many diseases. The survey reveals the conservation importance of the sacred grove to safe guard the ecosystem for sustainable development.
  • Chemical profiling of fern Cheilosoria mysurensis (Wall. ex Hook.) Ching & Shing and its biological activity
    Ramalingam Rakkimuthu, P Ananthi, P Sathishkumar, A M Ananda kumar, D Sowmiya
    Plant Science Today, 2023
    Cheilosoria mysurensis (Wall. ex Hook.) Ching & Shing, a medicinal fern traditionally used to treat burns, throat pain and bone fracture. There is no any scientific report regarding anticancer studies of this species. The aim of the study was to find out the chemical components through GC/MS analysis with their antioxidant and cytotoxic activity. GC-MS analysis shows primary ingredients viz, Cis-9, 10-epoxyoctadecan-1-ol and Oxiraneundecanoic acid, 3-pentyl-, methyl ester, trans were present. High free-radical scavenging activity has been discovered in 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and showed the IC50 value of 52.13±0.33. Furthermore, C. mysurensis also showed good cytotoxic effects against DLA and EAC cell lines with values of 72.9% and 79.5% at 200 µg/ml dose respectively. Overall findings suggested that the identified chemical compounds proved to be rich in antioxidant property. Further, this fern can be a good resource for pharma industry to produce novel anti-cancer drugs.
  • GREEN SYNTHESIS OF REDUCED GRAPHENE OXIDE SILVER NANOCOMPOSITE USING Anisomeles malabarica (L.) R. BR. LEAF EXTRACT AND ITS ANTIBACTERIAL ACTIVITY
    R. Rakkimuthu, S. Aarthi, E. Neelamathi, Palanivel Sathishkumar, A Anandakumar, et al.
    Rasayan Journal of Chemistry, 2022
    The development of new antimicrobial materials has arisen in response to the need to prevent and control the growth of pathogenic microorganisms without the use of antibiotics. The Silver (Ag) nanoparticles attached r-GO (rGO/Ag) nanocomposite was synthesised in the present work using a one-pot in-situ chemical reduction approach and studied for antibacterial property. We developed a rapid preparation of graphene from graphite using modified Hummers method and reduced by A. malabarica leaf extract. UV-Vis spectroscopy and FT-IR were used to characterize the synthesized GO and rGO–Ag nanocomposite. The antibacterial properties of the synthesized GO and rGo-Ag nanocomposite were evaluated against human pathogenic organisms like Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus using agar well diffusion method. At 50µl concentrations, synthesised GO inhibited Pseudomonas aeruginosa (19 mm) and rGO-Ag nanocomposite inhibited Staphylococcusaureus (28 mm).Antibacterial properties of the nanocomposites were found to be efficient against both gram positive and gram negative bacteria. Thus, green synthesized RGO-supported Silver nanoparticles play an important role in the medical disciplines.
  • Chemical Profiling of Momordica charantia L. Seed Essential Oil and Its Antimicrobial Activity
    Rakkimuthu Ramalingam, Sathishkumar Palanisamy, Ananda Kumar Mohanraj, Sowmiya Durisamy, Nishanthini Rajasekaran
    Journal of Essential Oil Bearing Plants, 2020
    Momordica charantia L. is an essential oil-bearing plant of the family Cucurbitaceae. Not much has been described about the plant on literature survey. Gas Chromatography/Mass Spectrometry (GC/ MS) analysis of the essential oil reported the presence of major volatile components, such as 5-(Hydroxymethyl) -2-(1-methyl-2-imidazolyl)-1H-benzimidazole (79.18 %) and as 2-Cyclohexen-1-one, 2-methyl-5-(1-methylethenyl), (R)- (13.90 %). The essential oil mainly consists of Benzimidazoles (79.18 %) and oxygen derivative monoterpenoids (13.09 %) in the total oil. The essential oil exhibited strong activity against all the tested bacteria such as Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae and Staphylococcus aureus, and antifungal activity against Candida tropicalis. The highest percentage of inhibition by the essential oil was found against the bacteria, K. pneumoniae followed by E. coli, S. aureus and P. aeruginosa respectively, and the fungi C. tropicalis. The present result revealed that essential oil of M. charantia seed possesses potent antimicrobial properties and could be taken as a source for the production of future antimicrobial drugs. This is the first report where the major compound 5-(Hydroxymethyl)-2-(1-methyl-2-imidazolyl)-1H-benzimidazole (79.18 %) was isolated from M. charantia seed oil from the Western Ghats of South India.Key word: Momordica charantia, essential oil, GC/MS, inhibition, antimicrobial properties.
  • Evaluation of antioxidant and DNA nicking potential of anthocyanin extracted from erythrina Indica flower petals
    Research Journal of Pharmaceutical Biological and Chemical Sciences, 2014
  • Quantitative phytochemical analysis and their antioxidant activity of Cocculus hiιrsutus (l.) Diels fruit
    International Journal of Phytomedicine, 2012

RECENT SCHOLAR PUBLICATIONS

  • Exploring the Ethno Medicinal Antioxidant Properties of Musa Paradisiaca Latex through Biochemical Assays
    R Rakkimuthu
    Indian Journal of Natural Sciences 16 (Issue 92), 100066-100071 , 2025
    2025
  • Evaluation of Bio-Fortified Composite for Improving Seed Quality Parameters on some Selected Crop Species
    AMA Kumar1*, R Rakkimuthu1, P Sathishkumar1, D Sowmiya1, ...
    Indian Journal of Natural Sciences 16 (90), 94336-94344 , 2025
    2025
  • Systematic Significance of Anatomical Characterization on Cleome Species of the Family Cleomaceae
    P Sathishkumar1*, J Logeshwari2, R Rakkimuthu3, AMAKD Sowmiya1
    Indian Journal of Natural Sciences 16 (89), 90752-90760 , 2025
    2025
  • Crafting Sugar-Free Anti-Diabetic Chocolate from Natural Sources
    R R, Saranyadevi M, S P, AAM Sowmiya D
    Indian Journal of Natural Sciences 16 (89), 92894-92901 , 2025
    2025
  • GC/MS Analysis of Methanolic Extract of Pancratium triflorum Roxb. bulbs
    AKAMSD Rakkimuthu R*, Neethu Krishna K , Sathishkumar P
    Indian Journal of Natural Sciences 15 (83), 73005-73008 , 2024
    2024
  • Formulation and evolution of eco-friendly foliar spray produced from kitchen wastes for better crop productivity
    PSKSM A.M. Anandakumar, Sri Kirubashini, R. Rakkimuthu
    Biospectra 19 (1), 235-244 , 2024
    2024
  • Qualitative and Quantitative analysis of the unexplored fern Thelypteris meeboldii from Southern Western Ghats, Tamilnadu
    PSSAMA D. Sowmiya, K. Vinothkumar, R.Rakkimuthu
    Indian Journal of Natural sciences 15, 83 , 2024
    2024
  • Floristic diversity and ethnobotanical studies of Nandha Gopalasamy hill temple sacred grove of Western Ghats, Pollachi Taluk, Coimbatore.
    AMA Kumar, D Rathika, R Rakkimuthu, P Sathishkumar
    2023
    Citations: 4
  • Chemical profiling of fern Cheilosoria mysurensis (Wall. ex Hook.) Ching & Shing and its biological activity.
    R Rakkimuthu, P Ananthi, P Sathishkumar, AMA Kumar, D Sowmiya
    2023
    Citations: 4
  • Pharmacocgnostical Characterisation and Phytochemical Profiling of the Medicinal Plant, Ehretia ovaliafolia Wight
    P R. Rakkimuthu A.M. Anandakumar
    Indian Journal of Natural Sciences , 2023
    2023
  • Edible coating from Nontoxic biomaterial for extending shelf life of fruits and vegetables
    DS P. sathishkumar, R. Rakkimuthu, A.M. Anandakumar
    Indian Journal of Natural Sciences 14 (78), 55936 , 2023
    2023
  • Production of Degradable Bio Plastics from Invasive Alien Plants in Anamalais, the Western Ghats
    DSVP P.Sathishkumar*, G.Chokkalingam , R.Rakkimuthu , AM. Ananda Kumar
    Indian Journal of Natural Sciences 13 (76), 52603 , 2023
    2023
  • SCREENING OF PHYTOCHEMICAL AND ANTIMICROBIAL ACTIVITY OF LITHOPHYTIC FERN PYRROSIA POROSA (C.PRESL) HOVENKAMP
    P D. Sowmiya, R. Rakkimuthu
    Indian journal of Natural Sciences 13 (76), 52680 , 2023
    2023
  • Green Synthesis of Silver Nanoparticles from Chaetomorpha antennina (Bory) Kützing and its Antibacterial Activity
    SDPK Rakkimuthu R, Nishana A, Sathishkumar P Anandakumar A.M
    Indian Journal of Natural Sciences 13 (75), 50384-50389 , 2022
    2022
  • GREEN SYNTHESIS OF REDUCED GRAPHENE OXIDE SILVER NANOCOMPOSITE USING Anisomeles malabarica (L.) R. BR. LEAF EXTRACT AND ITS ANTIBACTERIAL ACTIVITY
    R Rakkimuthu, S Aarthi, E Neelamathi, P Sathishkumar, ...
    Rasayan J. Chem 15, 417-422 , 2022
    2022
    Citations: 12
  • Chemical Profiling of Momordica charantia L. Seed Essential Oil and Its Antimicrobial Activity
    R Ramalingam, S Palanisamy, AK Mohanraj, S Durisamy, N Rajasekaran
    Journal of Essential Oil Bearing Plants 23 (2), 390-396 , 2020
    2020
    Citations: 9
  • Effect of herbal spray for coconut copra process, storage and Post-harvest disease management
    DS R Rakkimuthu, R Indu, P Sathishkumar, AM Anandakumar
    International Journal of Botany Studies 4 (6), 77-81 , 2019
    2019
  • IN VITRO ANTIFUNGAL ACTIVITY OF FORMULATED FLORAL EXTRACTS AGAINST MALASSEZIA FURFUR.
    AMADS R.Rakkimuthu, R. Nithiyakamatchi, P.Sathishkumar
    The International journal of analytical and experimental modal analysis 11 … , 2019
    2019
  • 'Quantitative phytochemical screening of Filicium decipiens Wight & Arn.,
    AMA D. Sowmiya and S. Sabirafathima P. Sathishkumar, D. Kaviya, R. Rakkimuthu
    American International Journal of Research in Science, Technology … , 2019
    2019
  • Effect of silver nanoparticles of Ulva fasciata in germination of selected pulses
    SS D. Sowmiya, R. Rakkimuthu, P. Sathishkumar, A. M. Anandakumar
    American International Journal of Research in Science, Technology … , 2019
    2019

MOST CITED SCHOLAR PUBLICATIONS

  • Effect of temperature, light, pH on the stability of anthocyanin pigments in Cocculus hirsutus fruits
    SPAS Rakkimuthu. R.
    International Journal of Multidisciplinary Research and Modern Education 2 … , 2016
    2016
    Citations: 37
  • In vitro micropropagation of Alpinia zerumbet Variegate, an important medicinal plant, through rhizome bud explants
    KM Rakkimuthu, R., Jinu Jacob, Aravinthan
    Research in Biotechnology 2 (-), 7-10 , 2011
    2011
    Citations: 18
  • Antibacterial activity of Crotalaria pallida Aiton. (Fabaceae)
    RRAKM Kiruthiga R
    Indian J. Pharm. Biol. Res 2 (1), 82-85 , 2014
    2014
    Citations: 15
  • Quantitative phytochemical analysis and their antioxidant activity of Cocculus hirsutus (l.) Diels fruit
    R Ramalingam, P Suganyadevi, KM Aravinthan
    International Journal of phytomedicine 4 (4), 447 , 2012
    2012
    Citations: 13
  • GREEN SYNTHESIS OF REDUCED GRAPHENE OXIDE SILVER NANOCOMPOSITE USING Anisomeles malabarica (L.) R. BR. LEAF EXTRACT AND ITS ANTIBACTERIAL ACTIVITY
    R Rakkimuthu, S Aarthi, E Neelamathi, P Sathishkumar, ...
    Rasayan J. Chem 15, 417-422 , 2022
    2022
    Citations: 12
  • Chemical Profiling of Momordica charantia L. Seed Essential Oil and Its Antimicrobial Activity
    R Ramalingam, S Palanisamy, AK Mohanraj, S Durisamy, N Rajasekaran
    Journal of Essential Oil Bearing Plants 23 (2), 390-396 , 2020
    2020
    Citations: 9
  • PHYTOCHEMICAL SCREENING AND ITS ANTIBACTERIAL ACTIVITY OF THE FERN HEMIONITIS ARIFOLIA (BURM.) MOORE
    LBKD R. Rakkimuthu, B. Naveenraj
    World Journal of Pharmaceutical Research 7 (13), 603-609 , 2018
    2018
    Citations: 8
  • Comparative antioxidant studies of in vivo leaves and in vitro callus of Crotalaria pallida Aiton (Fabaceae).
    KM Kiruthiga, R., Rakkimuthu, R. and Aravinthan
    Research in Pharmacy 2 (4), 01-15 , 2014
    2014
    Citations: 5
  • Floristic diversity and ethnobotanical studies of Nandha Gopalasamy hill temple sacred grove of Western Ghats, Pollachi Taluk, Coimbatore.
    AMA Kumar, D Rathika, R Rakkimuthu, P Sathishkumar
    2023
    Citations: 4
  • Chemical profiling of fern Cheilosoria mysurensis (Wall. ex Hook.) Ching & Shing and its biological activity.
    R Rakkimuthu, P Ananthi, P Sathishkumar, AMA Kumar, D Sowmiya
    2023
    Citations: 4
  • In vitro Propagation of Jatropha curcas Linn- A valuable Multipurpose Crop
    KM Nithya Priya. S, Rakkimuthu. R, Aravinthan
    Adv Bio Tech 11 (02), 24-25 , 2011
    2011
    Citations: 2
  • Evaluation of Antioxidant and DNA Nicking Potential of Anthocyanin Extracted from Erythrina indica Flower Petals
    KMPSD Reshmi, S. K., Kathiresh, M., Rakkimuthu, R., Aravinthan
    Res. J. Pharm., Biol. Chem. Sci. 4 (5), 718-725 , 2014
    2014
    Citations: 1
  • Exploring the Ethno Medicinal Antioxidant Properties of Musa Paradisiaca Latex through Biochemical Assays
    R Rakkimuthu
    Indian Journal of Natural Sciences 16 (Issue 92), 100066-100071 , 2025
    2025
  • Evaluation of Bio-Fortified Composite for Improving Seed Quality Parameters on some Selected Crop Species
    AMA Kumar1*, R Rakkimuthu1, P Sathishkumar1, D Sowmiya1, ...
    Indian Journal of Natural Sciences 16 (90), 94336-94344 , 2025
    2025
  • Systematic Significance of Anatomical Characterization on Cleome Species of the Family Cleomaceae
    P Sathishkumar1*, J Logeshwari2, R Rakkimuthu3, AMAKD Sowmiya1
    Indian Journal of Natural Sciences 16 (89), 90752-90760 , 2025
    2025
  • Crafting Sugar-Free Anti-Diabetic Chocolate from Natural Sources
    R R, Saranyadevi M, S P, AAM Sowmiya D
    Indian Journal of Natural Sciences 16 (89), 92894-92901 , 2025
    2025
  • GC/MS Analysis of Methanolic Extract of Pancratium triflorum Roxb. bulbs
    AKAMSD Rakkimuthu R*, Neethu Krishna K , Sathishkumar P
    Indian Journal of Natural Sciences 15 (83), 73005-73008 , 2024
    2024
  • Formulation and evolution of eco-friendly foliar spray produced from kitchen wastes for better crop productivity
    PSKSM A.M. Anandakumar, Sri Kirubashini, R. Rakkimuthu
    Biospectra 19 (1), 235-244 , 2024
    2024
  • Qualitative and Quantitative analysis of the unexplored fern Thelypteris meeboldii from Southern Western Ghats, Tamilnadu
    PSSAMA D. Sowmiya, K. Vinothkumar, R.Rakkimuthu
    Indian Journal of Natural sciences 15, 83 , 2024
    2024
  • Pharmacocgnostical Characterisation and Phytochemical Profiling of the Medicinal Plant, Ehretia ovaliafolia Wight
    P R. Rakkimuthu A.M. Anandakumar
    Indian Journal of Natural Sciences , 2023
    2023