Fatemeh Shafiee

Scopus Publications

Fabrication of a novel Ganoderma lucidum-integrated polyvinyl alcohol/sodium alginate hydrogel for advanced wound healing applications
Faezeh Yazdanparast, Mehdi Mehdikhani, Afsaneh Yegdaneh, Fatemeh Shafiee, Melika Babaei, Mohammad Rafienia
Heliyon, 2026
The treatment of skin injuries such as burns, lacerations, and chronic wounds often presents clinical and financial challenges, necessitating the development of advanced wound dressings that combine biocompatibility with therapeutic functionality. This study presents a novel hydrogel membrane incorporating Ganoderma lucidum (GL) extract into a polyvinyl alcohol (PVA) and sodium alginate (SA) matrix, developed using a freeze-thaw technique. Hydrogels with varying PVA:SA ratios (100:0, 90:10, 70:30, 50:50) were fabricated and evaluated for their structural, rheological, and mechanical properties. Increased SA content enhanced porosity (up to 90.54 ± 4.12%) and pore size (26.79 ± 1.78 μm), resulting in improved elasticity and flexibility suitable for skin applications. The 50:50 formulation exhibited optimal characteristics and was selected for GL incorporation at 5% and 10% (w/v). GL extract, obtained through maceration, exhibited high total phenolic content (60.48 mg GAE/g), indicative of potent antioxidant activity. FTIR analysis confirmed the hydrogel's chemical integrity. GL incorporation increased water uptake and reduced degradation over 28 days across pH conditions. In vitro release studies indicated quasi-Fickian diffusion, with 10% GL hydrogels achieving a faster release (81.18 ± 5.16%) at pH 7.4. Biocompatibility was confirmed via cell viability and adhesion assays, with the 5% GL hydrogel promoting superior cell proliferation and viability (98.19 ± 9.12%) by day 7. The integration of GL into a PVA-SA matrix introduces a bioactive wound dressing with enhanced regenerative potential, marking a significant advancement in the development of multifunctional, nature-inspired wound healing materials.
Peptide and Protein Tags for the Half-Life Extension of Therapeutic Agents: A Review Article
Sorour Aboutalebi, Fatemeh Najafi, Negin Yazdizadeh, Fatemeh Shafiee
Protein Journal, 2026
Evaluation of the Anti-melanogenic Effect of Aqueous and Hydroalcoholic Extracts of Nasturtium Officinale on the B16F10 Cell Line
Mohaddese Heydari, Masoud Sadeghi-Dinani, Fatemeh Shafiee
Avicenna Journal of Medical Biotechnology, 2026
Background: This project aimed to evaluate the anti-melanogenic characteristics of Nasturtium officinale (N. officinale) by assessing the impact of both aqueous and hydroalcoholic extracts on the inhibition of cellular and mushroom tyrosinase enzymes, as well as the suppression of the melanin synthesis in B16F10 melanoma cells.Methods: The aerial components of N. officinale were subjected to extraction using distilled water: ethanol (7:3) through the maceration technique. The extract’s phenolic compounds were quantified employing the Folin-Ciocalteu method. The evaluation of the safety profile of the extracts on B16F10 cells was done by the MTT assay. Subsequently, the melanin concentration in B16F10 cells, alongside the inhibitory effects on both mushroom and cellular tyrosinase, was assessed following treatment with the aforementioned extracts.Results: The aqueous and hydroalcoholic extracts exhibited no significant toxicity on B16F10 when compared to Phosphate-Buffered Saline (PBS). Additionally, there was no notable difference in the cytotoxic effects of extracts on the B16F10 cell line. Both extracts resulted in inhibition of cellular and mushroom tyrosinase, along with a decrease in melanin levels in B16F10 in a concentration-dependent manner. Ultimately, the total phenolic content in the aqueous and hydroalcoholic extracts was found to be approximately 14 and 30 mg/g of gallic acid, respectively.Conclusion: This in vitro investigation offers evidence supporting the skin brightening properties of N. officinale as an anti-melanogenic agent. Given its safety profile and absence of toxic effects on melanoma cells, it may be incorporated into the formulation of skin-brightening products following preclinical tests.
Intein-Mediated Production and Anti-tumor Evaluation of DT386-BR2 in Animal Model of Human Breast Cancer
Sajad Maghareh-Dehkordi, Taha Safi Ghahderijani, Melika Kolahdoozan, Fatemeh Moazen, Ardeshir Talebi, Fatemeh Shafiee, Ali Jahanian-Najafabadi
International Journal of Peptide Research and Therapeutics, 2026
Mutant soluble Interleukin-6 receptor as a potential agent for inhibiting cell migration and inducing apoptosis in a breast cancer cell line
Maryam Sadat Mousavizadeh-Marvast, Mina Mirian, Fatemeh Shafiee
Molecular Biology Reports, 2025
Preparation of Pluronic F127 hydrogel loaded with BIF1-iRGD recombinant protein for its targeted anti-cancer effects
Zahra Tamizifar, Abbas Jafarian-Dehkordi, Somayeh Taymouri, Fatemeh Shafiee
Research in Pharmaceutical Sciences, 2025
Background and purpose: Pluronic F127-based hydrogel is a fair formulation for increasing the protein stability and half-life without decreasing its biological activity. The present study aimed to prepare FP127 hydrogel loaded with the recombinant BIF1-iRGD protein as a new immunotoxin with targeting potential of cancer cells. Experimental approach: BIF1-iRGD in 19% w/v of FP127 was prepared by the cold method, and its in vitro release was determined. MTT and flow-cytometry assays were performed to evaluate the cytotoxic and apoptotic effects of BIF1-iRGD and BIFl-iRGD-hydrogel against 4T1 cells. The tumor size of 4T1 Balb-C mice was evaluated, and H&E staining was used for histopathology evaluation. Findings/Results: BIFl-iRGD release followed the first-order model. The toxicity of BIFl-iRGD was less than that in the formulation as a hydrogel after 48 and 72 h of treatment. The null hydrogel showed no toxicity compared to the untreated cells. After 24 h, cells treated with BIFl-iRGD-hydrogel and BIFl-iRGD around their 48-h IC 50 value developed apoptosis at about 55% and 35%, respectively. The tumor size decreased over time in the treated mice during the 20 days after the last injection. Also, no significant difference was observed between the effectiveness of the two groups. Tumor sections of mice treated with BIF1-iRGD and BIF1-iRGD-hydrogel had necrotic parts of about 65% and 70%, respectively. Conclusion and implications: BIF-iRGD-hydrogel showed in vivo anticancer effects with increased toxicity in comparison to the native protein. However, the investigation of protein distribution and probable cytotoxic effect on vital organs must be noted.
Characterization of enteric-coated capsules filled with colchicine loaded zein nanoparticles for colon delivery
Somayeh Taymouri, Somayeh Mirseyfifard, Fatemeh Shafiee
Therapeutic Delivery, 2025
AIM: In this study, we developed a dual pH and time-dependent formulation for targeted colonic release, aiming at minimizing adverse effect and enhancing anticancer efficacy of colchicine in the treatment of colorectal cancer. MATERIALS AND METHODS: To achieve this, colchicine was loaded in zein nanoparticles (Col-Z NP) which were further optimized and encapsulated in Eudragit S100 coated capsules. A full factorial design was employed to determine the optimal condition for preparation of Col-Z NP. RESULTS: The optimized Col-Z NPs exhibited a spherical shape with particle size of 104.3 ± 1.6 nm, polydispersity index of 0.27 ± 0.01, zeta potential of 29.0 ± 0.1 mV, encapsulation efficiency of 59.8 ± 4.8%, release efficiency over 8 h of 45.5 ± 2.7%, and drug loading of 13.0 ± 0.0%. No notable difference in cytotoxicity was observed between free colchicine and Col-Z NPs at comparable concentrations. The cellular uptake study showed more uptake for coumarin 6 loaded Z NPs compared to free coumarin 6. Colchicine release from coated capsules was restricted to around 3% in gastric medium and increased to about 8% in simulated intestine medium, respectively. CONCLUSION: Results suggest that Eudragit S100 coated capsules containing Col-Z NP could be effective delivery system for colchicine to target colorectal tumors.
Fractionation of Allium giganteum Effective Extract on Gastrointestinal Neoplasms Cell Lines for Its Anti-Proliferative Properties
Masoud Sadeghi Dinani, Mohammadreza Ghanbarzadeh, Fatemeh Shafiee
Advanced Biomedical Research, 2025
Background: This study was designed to investigate the various extracts of Allium giganteum in term of their cytotoxic effects on gastric and colon cancer cell lines and then fractionation of extract with the most desired effects on cancer cells in comparison to the normal cell line. Materials and Methods: The A. giganteum air-dried bulbs were extracted in four solvents including aqueous, butanol, chloroform: methanol (9:1), and dichloromethan extracts. Evaluating the cytotoxicity of extracts were done by MTT assay against HT-29, KATO-III, and HUVEC cell lines. The extract with The most cytotoxicity on cancer cells and lower toxicity on normal cell line was subjected to the fractionation by MPLC using a RP-18 silica gel column and in the next stage and the cytotoxicity of resulted fractions were determined by MTT assay. Results: Chloroform: methanol extract was the safest extract on HUVEC cells with great cytotoxic effects against cancer cell lines (IC50 17.3 and 23 µg/mL, for KATO-III and HT-29, respectively). The results of MTT assay for 7 fractions of the chloroform: methanol extract showed that 5th fraction (E) was the most cytotoxic fraction (IC50 9 and 11.2 µg/mL for HT-29 and KATO-III, respectively). TLC and NMR analysis of the fractions suggested the presence of steroidal saponins as the main constituents. Conclusion: Significant cytotoxic effects of Allium giganteum was established against GI cancer cell lines especially fractions rich in steroidal saponins. So, these fractions are attractive candidate for the isolation and identification of effective ingredients.
Apoptosis-inducing proteins with reduced expression in breast cancer: A review article
Mohammad Mehdi Khaleghi, Faezeh Rouhi, Kourosh Eslami, Fatemeh Shafiee
Biochemistry and Biophysics Reports, 2025
Breast cancer is considered one of the most abundant malignancies with high morbidity and mortality. Traditional cancer treatments possess various weaknesses, including a lack of specificity and numerous side effects. Novel cancer therapies aim to overcome the shortcomings of traditional therapies and offer more efficient and safe treatments. Designing and identifying novel proteins that can practically and specifically inhibit tumors by inducing apoptosis can interest researchers in this field. This review discusses recent studies on the use of four promising proteins, KAI1, Apoptin, BIF-1, and DFF-40, for breast cancer treatment. This study also focuses on alterations in the expression of the androgenic proteins and novel strategies for better penetration and delivery of these proteins. Lastly, prospects for protein-based targeted cancer therapy and future studies in this field are highlighted. • Apoptotic proteins with diminished expression in breast cancer can be assumed as potential treatment approach for this problem. • Apoptotic proteins with diminished expression in breast cancer can be assumed as tumor marker for diagnosis of this disorder. • These apoptosis-inducing proteins generally have decreased expression levels in cancer, while tumor markers have increased expression levels with no specifity to a unique type of cancer. • Checking the expression level of these proteins can encourage us to use their replacement therapy for the apoptotic death of cancer cells. • The effective use of each of these strategies is conditional on determining their efficacy and safety during the clinical trial phases.
In vitro Evaluation of the Cytotoxic Effects of a Recombinant form of the Soluble Mutant IL-6 Receptor on an Ovarian Cancer Cell Line
Kosar Khatir, Mahmoud Aghaei, Seyedeh Sara Ghorbanhosseini, Fatemeh Shafiee
Iranian Journal of Biotechnology, 2025
Background: Interleukin-6 (IL-6) plays an important role in cancer metastasis. Therefore, it seems that inhibition of IL-6 may act as an anticancer agent. Objectives: This study examined the anti-proliferative and IL-6 signal transduction inhibitory effects of a mutant IL-6 receptor (mIL-6R) on an ovarian cancer cell line. Materials and Methods: BL21 at various inducer concentrations and temperatures. The expressed protein was purified using the IMPACT system, and the best-examined conditions (i.e., temperature, time, cleavage buffer pH) for intein1auto-cleavage were achieved. The anti-proliferative effects of mIL-6R on OVCAR-3 cancer cells were investigated using MTT assay and RT-PCR to determine its effects on suppressing the JAK-STAT pathway genes. Results: The highest solubility of mIL-6R was obtained at 20 °C, 0.5 mM IPTG. The highest level of intein1 cleavage occurred at 25 °C, 24 hours of incubation, and pH = 4 of cleavage buffer. Also, mIL-6R diminished the survival of OVCAR-3 cells compared to PBS (p-value = 0.024), with 48 hours IC50 of 1.117 μg/mL. Also, mIL-6R significantly reduced the expression of the JAK, STAT, and VEGF genes. Conclusion: The recombinant mIL-6R showed a strong concentration-dependent anti-proliferative effect on the OVCAR-3 cell line. However, it needs further evaluation for its potential activity against disorders associated with increased IL-6.
DNA fragmentation factor 40-based therapeutic approaches for cancer: a review article
Faezeh Masaeli, Saba Omoomi, Fatemeh Shafiee
Medical Oncology, 2024
Kinetic studies, molecular docking, and antioxidant activity of novel 1,3-diphenyl pyrazole-thiosemicarbazone with anti-tyrosinase and anti-melanogenesis properties
Fateme Azimi, Mohammad Mahdavi, Mehdi Khoshneviszadeh, Fatemeh Shafiee, Mahin Azimi, Farshid Hassanzadeh, Farhad Haji Ashrafee
Bioorganic Chemistry, 2024
Optimization of the Production of Soluble Recombinant TEV Protease in Two E. coli Strains
Matineh Shahriari, Fatemeh Shafiee, Fatemeh Moazen, Hamid Mir Mohammad Sadeghi
Avicenna Journal of Medical Biotechnology, 2024
Intein Based Fusion Proteins: Great Tags for the Soluble Production and Convenient Purification of Recombinant Proteins
Fatemeh Shafiee, S. Sharifi, Armin Amini
Iranian Journal of Biotechnology, 2024
Recombinant production of interleukin-1 receptor antagonist in fusion to albumin binding domain with potential affinity to human serum albumin
Fatemeh Shafiee, Ali Yazdani
Research in Pharmaceutical Sciences, 2024
Production of recombinant DNA fragmentation factor 40 in fusion to an antimicrobial peptide from spider venom and evaluation of its cytotoxic effects
Zahra Shafiee-Ardestani, Fatemeh Shafiee
Research in Pharmaceutical Sciences, 2024
Recombinant Production of TP4-LYC1, A New Chimeric Peptide with Targeted Cytotoxicity to HeLa Cells
Hanieh Mohammad Pour, Ali Jahanian-Najafabadi, Fatemeh Shafiee
Avicenna Journal of Medical Biotechnology, 2024
An investigation to find the correlation between lupus anticoagulant and coagulation abnormalities in COVID-19 patients; a narrative review
Amir Aria, Ahmadreza Maghsoudi, Fatemeh Shafiee, Mahnaz Momenzadeh
Journal of Nephropathology, 2024
The Antimicrobial Effects of TP4-LYC1 Fusion Protein against Multidrug-Resistant A. Baumannii
رسول سلطانی, فاطمه صادقی کوپایی, فاطمه شفیعی
Journal of Isfahan Medical School, 2023
Preparation and in Vitro Evaluation of Inhalation Powder Containing Fluconazole Nanoparticles for the Treatment of Fungal Lung Infections
سمیه تیموری, حمیدرضا انصاری, فاطمه شفیعی, ژاله ورشوساز
Journal of Isfahan Medical School, 2023
Design and construction of scFv-PE35KDEL as a novel immunotoxin against human epidermal growth factor receptor 2 for cancer therapy
Zahra Shariaty Vaziri, Fatemeh Shafiee, Vajihe Akbari
Biotechnology Letters, 2023
Arsenic Polyoxotungstate-Zeolitic Imidazolate Framework-8 as a Potential Selective Anti-cancer Nano Platform
Zahra Moazeni Bistgani, Fatemeh Shafiee, Jaleh Varshosaz, Hossein Kazemian, Shahram Tangestaninejad, Mahboubeh Rostami
Journal of Inorganic and Organometallic Polymers and Materials, 2023
Development and evaluation of wafer loaded with sertaconazole solid dispersion for the treatment of oral candidiasis
Horieh Hajhashemi, Somayeh Taymouri, Fatemeh Shafiee
Brazilian Journal of Pharmaceutical Sciences, 2023
Andrographolide protects against doxorubicin-and arsenic trioxide-induced toxicity in cardiomyocytes
Leila Safaeian, Fatemeh Shafiee, Samira Haghighatnazar
Molecular Biology Reports, 2023
Invasive fungal infections in hematologic malignancies: Incidence, management, and antifungal therapy
Fatemeh Shafiee, Rasool Soltani, Mohsen Meidani
Journal of Research in Medical Sciences, 2023
The effectiveness of colistin/levofloxacin compared to colistin/meropenem in the treatment of ventilator-associated pneumonia (VAP) caused by carbapenem-resistant Acinetobacter baumannii: a randomized controlled clinical trial
Rasool Soltani, Mahnaz Momenzadeh, Fatemeh Shafiee, Atousa Hakamifard, Morteza Pourahmad, Saeed Abbasi
Research in Pharmaceutical Sciences, 2023
Internalizing RGD, a great motif for targeted peptide and protein delivery: a review article
Zeinabosadat Davoodi, Fatemeh Shafiee
Drug Delivery and Translational Research, 2022
Cytotoxic and Apoptotic Effects of Flavonoids and a Geraniol Derivative from Artemisia kermanensis on Normal and Breast Cancer Cell Lines
Elahe Kazemi, Fatemeh Shafiee, Zeinab Yazdiniapour
Research Journal of Pharmacognosy, 2022
BR2, a Buforin Derived Cancer Specific Cell Penetrating Peptide for Targeted Delivering of Toxic Agents: a Review Article
Fatemeh Sadeghi, Marziyeh Kajbaf, Fatemeh Shafiee
International Journal of Peptide Research and Therapeutics, 2022
Cytotoxicity and apoptosis assay of novel cyclomyrsinol diterpenes against breast cancer cell lines
Fatemeh Shafiee, Faezeh Rabbani, Zeinab Yazdiniapour, Mustafa Ghanadian, Behzad Zolfaghari, Melika Maleki
World Journal of Traditional Chinese Medicine, 2022
Rational design of a new variant of Reteplase with optimized physicochemical profile and large-scale production in Escherichia coli
Hooria Seyedhosseini Ghaheh, Shabnam Sajjadi, Fatemeh Shafiee, Ebrahim Barzegari, Fatemeh Moazen, Hamid Mir Mohammad Sadeghi
World Journal of Microbiology and Biotechnology, 2022
Recombinant Production of a Mutant Form of Soluble IL-6 Receptor with Inhibitory Effects against Interleukin-6
Saba Feghhi-Najafabadi, Fatemeh Shafiee
Iranian Journal of Biotechnology, 2022
Pramlintide: An amylin analogue protects endothelial cells against oxidative stress through regulating oxidative markers and NF-κb expression
Leila Safaeian, Fatemeh Shafiee, Marzieh Naderi
International Journal of Preventive Medicine, 2022
In Vitro Evaluation the Anti-Melanogenic Effects of Various Extracts of Oat Seeds
Iranian Journal of Pharmaceutical Sciences, 2022
L-carnitine supplementation ameliorates insulin resistance in critically ill acute stroke patients: A randomized, double-blinded, placebo-controlled clinical trial
Shadi Farsaei, Malihe Nejati, Saeed Abbasi, Fatemeh Shafiee
Research in Pharmaceutical Sciences, 2022
Antibiotic resistance pattern of Helicobacter pylori strains isolated from patients in Isfahan, Iran
Hajarsadat Sadeghi, T Narimani, Elham Tabesh, Fatemeh Shafiee, Rasool Soltani
Journal of Research in Medical Sciences, 2022
DFF40-iRGD, a novel chimeric protein with efficient cytotoxic and apoptotic effects against triple-negative breast cancer cells
Raheleh Amrollahi-nia, Vajihe Akbari, Fatemeh Shafiee
Biotechnology Letters, 2021
Corrigendum to: “Novel and emerging mutations of SARS-CoV-2: Biomedical implications” [Biomed. Pharmacother. 139 (2021) 111599] (Biomedicine & Pharmacotherapy (2021) 139, (S075333222100384X), (10.1016/j.biopha.2021.111599))
Elmira Mohammadi, Fatemeh Shafiee, Kiana Shahzamani, Mohammad Mehdi Ranjbar, Abbas Alibakhshi, Shahrzad Ahangarzadeh, Leila Beikmohammadi, Laleh Shariati, Soodeh Hooshmandi, Behrooz Ataei, Shaghayegh HaghjooyJavanmard
Biomedicine and Pharmacotherapy, 2021
Survivin Promoter-Driven DFF40 Gene Expression Sensitizes Melanoma Cancer Cells to Chemotherapy
Ghazale Minaiyan, Fatemeh Shafiee, Vajihe Akbari
International Journal of Toxicology, 2021
In vitro synergistic effect of colistin and ampicillin/sulbactam with several antibiotics against clinical strains of multi-drug resistant Acinetobacter baumannii
Fatemeh Shafiee, Seyed Saeed Naji Esfahani, Atousa Hakamifard, Rasool Soltani
Indian Journal of Medical Microbiology, 2021
Novel and emerging mutations of SARS-CoV-2: Biomedical implications
Elmira Mohammadi, Fatemeh Shafiee, Kiana Shahzamani, Mohammad Mehdi Ranjbar, Abbas Alibakhshi, Shahrzad Ahangarzadeh, Leila Beikmohammadi, Laleh Shariati, Soodeh Hooshmandi, Behrooz Ataei, Shaghayegh Haghjooy Javanmard
Biomedicine and Pharmacotherapy, 2021
Recombinant Production and One-Step Purification of IL-1Ra in Escherichia coli and Evaluation of its IL-1 Antagonizing Efficacy
Roya Adelnia, F. Shafiee
Iranian Journal of Immunology, 2021
An innovative approach to fabricate a thermosensitive melatonin-loaded conductive pluronic/chitosan hydrogel for myocardial tissue engineering
Hadis Torabi, Mehdi Mehdikhani, Jaleh Varshosaz, Fatemeh Shafiee
Journal of Applied Polymer Science, 2021
Cytotoxicity and apoptosis inducing effects of some lathyrane and tigliane diterpenes against breast cancer cell lines
Melika Maleki, Zeinab Yazdiniapour, Mustafa Ghanadian, Behzad Zolfaghari, Faezeh Rabbani, Fatemeh Shafiee
Traditional and Integrative Medicine, 2021
Antimicrobial susceptibility pattern of carbapenemase-producing gram-negative nosocomial bacteria at al zahra hospital, isfahan, iran
Iranian Journal of Microbiology, 2021
Persicoimidate isolated from allium ampeloprasum subsp. Persicum with apoptotic effects against breast cancer cell lines
Iranian Journal of Pharmaceutical Sciences, 2020
Fluoxetine as an antidepressant medicine improves the effects of ionizing radiation for the treatment of glioma
Seyed Jalal Hosseinimehr, Seydeh Halimeh Najafi, Fatemeh Shafiee, Sodabeh Hassanzadeh, Soghra Farzipour, Arash Ghasemi, Hossein Asgarian-Omran
Journal of Bioenergetics and Biomembranes, 2020
Expression and one step intein-mediated purification of biologically active human G-CSF in Escherichia coli
Setareh Sima, Fatemeh Shafiee, Ali Jahanian-Najafabadi
Molecular Biology Reports, 2020
In silico design of two novel fusion proteins, p28-IL-24 and p28-M4, targeted to breast cancer cells
Ali Jahanian-Najafabadi, Reza Ghavimi, Elmira Mohammadi, Vajihe Akbari, Fatemeh Shafiee
Research in Pharmaceutical Sciences, 2020
Evaluation of cytotoxic and apoptotic effects of DT386-BR2: A promising anticancer fusion protein
Ali Jahanian-Najafabadi, Fatemeh Shafiee, Mohammad Rabbani
Journal of Reports in Pharmaceutical Sciences, 2020
Coenzyme Q10 improves the survival and reduces inflammatory markers in septic patients
R. Soltani, B. Alikiaie, F. Shafiee, H. Amiri, S. Mousavi
Bratislava Medical Journal, 2020
Targeted Diphtheria Toxin-Based Therapy: A Review Article
Fatemeh Shafiee, Marc G. Aucoin, Ali Jahanian-Najafabadi
Frontiers in Microbiology, 2019
Expression, purification, and cytotoxic evaluation of IL24-BR2 fusion protein
Fatemeh Shafiee, Marjan Pourhadi, Fahimeh Jamalzade, Ali Jahanian-Najafabadi
Research in Pharmaceutical Sciences, 2019
Introduction of a novel cancer cell targeted fusion protein: DT386-BR2
A. Jahanian-Najafabadi, F. Shafiee, M. Rabbani
Annals of Oncology, 2018
Recombinant Production and Intein-Mediated Purification of an Antimicrobial Peptide, BR2
Fatemeh Shafiee, Ghazale Minaiyan, Fatemeh Moazen, Ali Jahanian-Najafabadi
International Journal of Peptide Research and Therapeutics, 2017
In-vivo evaluation of DT386-BR2, a promising anticancer fusion protein, in mice model
Journal of Isfahan Medical School, 2017
Production and evaluation of cytotoxic effects of DT386-BR2 fusion protein as a novel anti-cancer agent
Fatemeh Shafiee, Mohammad Rabbani, Ali Jahanian-Najafabadi
Journal of Microbiological Methods, 2016
Expression and purification of truncated diphtheria toxin, DT386, in Escherichia coli: An attempt for production of a new vaccine against diphtheria
Ali Jahanian-Najafabadi, Fatemeh Shafiee, Mohammad Rabbani, Mahdi Behdani
Research in Pharmaceutical Sciences, 2016
Isolation and characterization of a new Thermoalkalophilic lipase from soil bacteria
Iranian Journal of Pharmaceutical Research, 2015
Optimization of the expression of reteplase in Escherichia coli TOP10 using arabinose promoter
Fatemeh Shafiee, Fatemeh Moazen, Mahammad Rabbani, Hamid Mir Mohammad Sadeghi
Jundishapur Journal of Natural Pharmaceutical Products, 2015

Fatemeh Shafiee

RESEARCH INTERESTS

Scopus Publications