Camila Maria Gonzales

@sites.usp.br

Departamento de Ciência e Tecnologia de Alimentos (LCA) da Esalq/USP
Universidade de São Paulo

Camila Maria Gonzales


                           Download Compact PDF  
https://researchid.co/goncamila

RESEARCH, TEACHING, or OTHER INTERESTS

Food Science, Nutrition and Dietetics, Agricultural and Biological Sciences, Multidisciplinary
1

Scopus Publications

25

Scholar Citations

1

Scholar h-index

1

Scholar i10-index

Scopus Publications

  • New Insights of Turmeric Extract-Loaded PLGA Nanoparticles: Development, Characterization and In Vitro Evaluation of Antioxidant Activity
    Camila Maria Gonzales, Luciana Facco Dalmolin, Kátia Aparecida da Silva, Natália Bueno Leite Slade, Renata Fonseca Vianna Lopez, Jeferson Aparecido Moreto, Kélin Schwarz
    Plant Foods for Human Nutrition, 2021
    Here, we presented new insights of the development of poly(lactic-co-glycolic acid) nanoparticles containing turmeric compounds (turmeric-PLGA-NPs) using emulsion-solvent evaporation method. The nanoparticulate system was characterized by size, zeta potential, morphology, release profile, partition parameter, stability and encapsulation efficiency (%EE). Antioxidant activity studies were also evaluated. The Korsmeyer-Peppas model (Mt/M∞ vs. t) was used to determine the release mechanisms of the studied system. Our results demonstrated the emulsion-solvent evaporation method was shown advantageous for producing turmeric-PLGA-NPs in the range of 145 nm with high homogeneity in size distribution, zeta potential of −21.8 mV and %EE about 72%. Nanoparticles were stable over a period of one month. In vitro study showed a release of curcumin governed by diffusion and relaxation of the polymeric matrix. The partition parameter of the extract in relation to blank-PLGA-NPs was 0.111 ± 0.008 M−1, indicating a low affinity of curcumin for the polymer matrix. Antioxidant ability of the turmeric-PLGA-NPs in scavenging the radical 2,2-azinobis (3-ethylbenzothiazoline- 6-sulfonic acid) (ABTS) was inferior to free turmeric extract and showed a concentration and time-dependent profile. The study concluded that PLGA nanoparticles are potential carriers for turmeric extract delivery.

RECENT SCHOLAR PUBLICATIONS

  • Microencapsulation of bioactive compounds from avocado oil residues
    CM Gonzales
    Universidade de São Paulo , 2024
    2024
    Citations: 1
  • New Insights of Turmeric Extract-Loaded PLGA Nanoparticles: Development, Characterization and In Vitro Evaluation of Antioxidant Activity
    CM Gonzales, LF Dalmolin, KA da Silva, NBL Slade, RFV Lopez, ...
    Plant Foods for Human Nutrition 76 (4), 507-515 , 2021
    2021
    Citations: 24

MOST CITED SCHOLAR PUBLICATIONS

  • New Insights of Turmeric Extract-Loaded PLGA Nanoparticles: Development, Characterization and In Vitro Evaluation of Antioxidant Activity
    CM Gonzales, LF Dalmolin, KA da Silva, NBL Slade, RFV Lopez, ...
    Plant Foods for Human Nutrition 76 (4), 507-515 , 2021
    2021
    Citations: 24
  • Microencapsulation of bioactive compounds from avocado oil residues
    CM Gonzales
    Universidade de São Paulo , 2024
    2024
    Citations: 1