Assoc. Prof. Dr. Gülin Gökçen Kesici graduated from Hacettepe University Faculty of Medicine in 2005. She completed her residency training in Otorhinolaryngology–Head and Neck Surgery at Ankara University Faculty of Medicine between 2007 and 2012.
She obtained her MSc in Audiology and Speech-Voice Disorders from Başkent University in 2016 and completed her PhD in Audiology at the same university in 2022. She received the title of Associate Professor in Otorhinolaryngology in 2020.
EDUCATION
PhD in Audiology, Başkent University, Ankara, Türkiye, 2022
MSc in Audiology and Speech–Voice Disorders, Başkent University, Ankara, Türkiye, 2016
Residency in Otorhinolaryngology–Head and Neck Surgery, Ankara University Faculty of Medicine, Ankara, Türkiye, 2012
MD (Doctor of Medicine), Hacettepe University Faculty of Medicine, Ankara, Türkiye, 2005
RESEARCH, TEACHING, or OTHER INTERESTS
Otorhinolaryngology, Speech and Hearing
19
Scopus Publications
Scopus Publications
A new perspective on the clinical features of vestibular migraine Gülin Gökçen Kesici, Büşra Kaplan Egyptian Journal of Otolaryngology, 2024 Background Diagnosis of vestibular migraine (VM) is complicated by its variable clinical presentation and lack of pathognomonic tests. Results Two-hundred fifty-eight vestibular attacks of 141 patients were evaluated. In a total of 141 patients, 26% of patients reported no headache. A total of 81% of the patients without headache reported pressure heaviness in the head and head numbness and reported aggravation of these symptoms by routine physical activity. In the group of pVM, 23 patients could not be classified as dVM; they had present or past history of migraine but did not have migrainous characteristics in at least 50% of their vestibular attacks, and 15 of these patients were diagnosed with dVM during follow-up. At least mild central ocular signs were observed in 59 (22%), and impairment in vVOR test (horizontal and/or vertical) was observed in 81 (31%) of 258 vestibular attacks. In vHIT test, 68 (26%) attacks with low VOR gain and refixation saccades and 151 (58%) attacks with normal VOR gain and pathological saccades were detected. Conclusions The heterogeneity in clinical and vestibular tests detected in this study, both in patients and in different attacks of the same patients, revealed the importance of taking a detailed history in the diagnosis of VM.
The effectiveness of the Milan system for risk stratification of salivary gland lesions: The 10-year cytohistopathological correlation results of salivary gland FNA cytology at a tertiary center Aysegul Aksoy Altinboga, Fatma Yildirim, Hilal Ahsen, Merve Meryem Kiran, Gulin Gokcen Kesici, Gokhan Yuce Diagnostic Cytopathology, 2021 BackgroundThe Milan system reporting salivary gland cytopathology (MSRSGC) is a tiered classification scheme that is based on risk stratification. The aim of the current study was to assess the risk of malignancy (ROM) and risk of neoplasia (RON) in each of the diagnostic categories proposed by the MSRSGC.MethodsA retrospective analysis and categorization according to the MSRSGC was made of salivary gland fine needle aspirations (FNA) performed from January 2007 to December 2017. The FNA cytology results were correlated with subsequent histological follow‐up.ResultsA total of 578 FNAs were evaluated and histopathology was available for 198 cases (34.2%). The RON and ROM for individual diagnostic categories were: Non‐diagnostic: 52.2% to 13%, non‐neoplastic: 21.4% to 10.7%, atypia of undetermined significance: 74% to 22.2%, benign neoplasm: 100% to 1.1%, salivary gland neoplasm of uncertain malignant potential: 93.3% to 53.3%, suspicious for malignancy (SFM): 100% to 100%, and malignant: 100% to 100%. A diagnosis of 'SFM' or 'malignant' with FNA cytology carried a 100% risk for malignancy, while a diagnosis of “non‐neoplastic,” “benign neoplasm” reduced the probability of malignancy to 3.4%.ConclusionThe MSRSGC is useful for the management of salivary gland lesions as it can successfully differentiate between benign and malignant cases. It will bring uniformity in salivary gland FNA cytology reporting across various institutions globally.
Association of Toll-Like Receptor Polymorphisms With Nasal Polyposis Gülin Gökçen Kesici, Selda Kargın Kaytez, Talih Özdaş, Sibel Özdaş Ear Nose and Throat Journal, 2021 Nasal polyposis is a disease characterized with chronic inflammation of the nasal mucosa. Toll-like receptors (TLRs) are defined as essential receptors of the innate immune system and may play in the development of nasal polyposis. A total of 71 patients with nasal polyposis and 74 healthy controls were included in this study. Three single-nucleotide polymorphisms (SNPs); TLR2 (2258 A>G), TLR4 (896 A>G), and TLR4 (1196 C>T) were analyzed in all patients. The degree of pair-wise linkage disequilibrium and the genotype and haplotype analyses were conducted using regression in this logistic model and the Multifactor Dimensionality Reduction (MDR) software package was used to construct all possible interactions among different genotype variants belonging to the TLR gene. There was significant difference in genotype and allele frequencies of the TLR4 (1196 C>T) polymorphism between the nasal polyposis and control groups (0.017). Also, it was observed that the probability of nasal polyposis was 62.7% in the presence of TLR4 (1196 C>T) polymorphism with asthma ( P = .007). As a conclusion, this study showed that TLR4 and TLR2 polymorphisms were predisposing factors for nasal polyposis. Further functional studies investigating the consequences of loss of TLR function are needed.
Investigation of Oxidative Stress in Antrochoanal Polyp Etiology Yuce Islamoglu, Gulin Gokcen Kesici, Yagmur Canan, Hayati Kale, Özmen Kara, Ozcan Erel, Mehmet Ali Babademez Ear Nose and Throat Journal, 2020 Antrochoanal polyps (ACPs) are benign lesions of the paranasal sinuses. Similarities between ACPs and nasal polyps have been previously investigated. However, oxidative stress has been implicated but not investigated in terms of the etiology of ACPs. Thus, the aim of this study was to investigate oxidative stress in the etiology of ACPs. The study population comprised 93 patients divided into 3 groups. Group 1 consisted of 30 patients with ACPs. Group 2 consisted of 33 patients with nasal septal deviation. Group 3 comprised 30 healthy individuals. Venous blood was taken from all participants, and total thiol, native thiol, disulfide, and ischemic modified albumin (IMA) levels were evaluated. When the values of native thiol ( P = .097), disulfide ( P = .221), total thiol ( P = .140), and IMA ( P = .091) were compared, no significant differences were found among the 3 groups. While many studies have been conducted related to nasal pathologies and the role of oxidative stress in their etiologies, our study concluded that oxidative stress plays no role in ACP etiology.
Comparison between curettage adenoidectomy and endoscopic-assisted microdebrider adenoidectomy in terms of Eustachian tube dysfunction Mahmut Huntürk Atilla, Selda Kargın Kaytez, Gülin Gökçen Kesici, Sibel Baştimur, Sebahattin Tuncer Brazilian Journal of Otorhinolaryngology, 2020 Adenoidectomy can be performed with many ways, including curettage and microdebrider endoscopic-assisted adenoidectomy. Those two techniques have advantages and disadvantages. The objective of this study is to research the effects of curettage adenoidectomy and endoscopic-assisted microdebrider adenoidectomy on the tympanum pressures in pediatric patients with adenoid hypertrophy without otitis media with effusion. This prospective descriptive study was performed with 65 patients who had a normal tympanic membrane and normal tympanogram and then underwent adenoidectomy or adenotonsillectomy for adenoid and tonsil hypertrophy. The subjects were randomly divided into two groups: curettage adenoidectomy group and endoscopic microdebrider-assisted adenoidectomy group. They underwent tympanometry, and the preoperative as well as 1st and 7th day postoperative values of the tympanum pressures were compared within and among the groups. There were 32 patients in the curettage adenoidectomy group and 33 patients in the microdebrider adenoidectomy group. Statistically significant differences were observed in the median tympanum pressure on the preoperative and 1st and 7th postoperative days for both the left and right ears with curettage adenoidectomy (p < 0.001, p < 0.001). This difference occurred on the 1st postoperative day, and the value returned to normal on the 7th day. There was no significant difference in the median tympanum pressure on the preoperative and 1st and 7th postoperative days for both the left and right ears in the microdebrider adenoidectomy group (p = 0.376, p = 0.128). Postoperative Eustachian tube dysfunction is seen less often with the endoscopic-assisted microdebrider adenoidectomy technique than with the conventional adenoidectomy technique. A adenoidectomia pode ser realizada de várias maneiras, inclusive por curetagem e por microdebridador, assistida por endoscopia. Essas duas técnicas têm algumas vantagens e desvantagens. O objetivo deste estudo foi investigar os efeitos da técnica de adenoidectomia por curetagem e da adenoidectomia por microdebridador assistida por endoscopia sobre a pressão timpânica em pacientes pediátricos com hipertrofia adenoideana sem otite média com efusão. Estudo descritivo prospectivo feito com 65 pacientes que apresentavam membrana timpânica e timpanograma normais, que foram então submetidos à adenoidectomia ou adenotonsilectomia por hipertrofia adenoamigdaliana. Os pacientes foram divididos aleatoriamente em dois grupos: grupo adenoidectomia por curetagem e grupo adenoidectomia por microdebridador assistida por endoscópio. Todos os pacientes fizeram timpanometria e os valores das pressões do tímpano pré-operatórios e pós-operatórios no 1° e 7° dias foram comparados intragrupos e entre os grupos. Foram incluídos 32 pacientes no grupo adenoidectomia por curetagem e 33 pacientes no grupo adenoidectomia com microdebridador. Diferenças estatisticamente significantes foram observadas na mediana da diferença entre a pressão timpânica no pré-operatório e no 1° e 7° dias de pós-operatório para ambas as orelhas, direita e esquerda, na adenoidectomia por curetagem (p < 0,001, p < 0,001). Essa diferença ocorreu no 1° dia do pós-operatório e o valor retornou ao normal no 7° dia. Não houve diferença significante na mediana entre pressão timpânica no pré-operatório e no 1° e 7° dias de pós-operatório para as orelhas direita e esquerda no grupo de adenoidectomia com microdebridador (p = 0,376, p = 0,128). A disfunção tubária no pós-operatório é observada menos frequentemente com a técnica de adenoidectomia por microdebridador assistida por endoscopia quando comparada com a técnica convencional.
Occupational allergy to dog among police dog trainers G.G. Kesici, A. Karataş, İ. Ünlü, E. Tutkun European Annals of Allergy and Clinical Immunology, 2019 Summary: This study was aimed to reveal the prevalence of dog allergy and other common allergy and allergic symptoms in police dog trainers. Fifty-six police dog trainers and 150 workers as control group were included in this study. Medical records of dog trainers including respiratory, skin, eye symptoms and physical examinations and skin prick test results are compared with the medical records of control group. Positive SPT to dog was present in 21.4% of dog trainers, whereas the frequency of sensitization to dog in the control group was 1.3% (p minor 0.001). Dog allergy development risk is found 20 times greater in dog trainers than control group. In multiple logistic regression analysis, it was found that atopy was associated with dog allergy likelihood. Sensitization to dog allergens is an important occupational problem for dog trainers.
New wand coblation turbinator vs coblation radiofrequency Yuce Islamoglu, Gulın Gokcen Kesici, Kadır Sınası Bulut, Ebubekır Alper Ozer, Yagmur Canan Teleke, Mehmet Ali Babademez American Journal of Otolaryngology Head and Neck Medicine and Surgery, 2019
Arsenic related hearing loss in miners Gülin Gökçen Kesici, İlhan Ünlü, Arzu Baştürk Topçu, Ceylan Demir Bal, Engin Tutkun, Ömer Hınç Yılmaz American Journal of Otolaryngology Head and Neck Medicine and Surgery, 2016