Brief outline CV
Prof. Priv. Doz. MMag. DDr. Giacomuzzi
Personal data
Date of birth October 07, 1965
Place of birth Innsbruck, Austria
Nationality Austrian
Mobile +43 650 2835868
E-Mail office@
Homepage
Languages
Mother tongue: German, Italian.
Excellent English
Fair: Spanish
Basic Knowledge: Portuguese, French, Dutch
Education
1996 PhD Experimental/Medical Physics; University of Innsbruck.
2002 PhD Psychology; University of Innsbruck
2005 Habilitation in Psychology
2019 Accolade Prof. h.c.
University Affiliations
University of Innsbruck
UMIT
Centre for Security Studies – University for Economy Cracow
Ivan Franko National University of Lviv, Ukraine - Faculty of Philosophy
Poltava V. G. Korolenko National Pedagogical University - Department of Psychology
Internation Security Competence Centre – ISCC Vienna
Outline of teaching activities
University for Econo
RESEARCH, TEACHING, or OTHER INTERESTS
Clinical Psychology, Applied Psychology, General Psychology, Public Health, Environmental and Occupational Health
54
Scopus Publications
Scopus Publications
Slow release oral morphine versus methadone for the treatment of opioid use disorder Jan Klimas, Lauren Gorfinkel, Salvatore M Giacomuzzi, Christian Ruckes, M Eugenia Socías, Nadia Fairbairn, Evan Wood BMJ Open, 2019 Objective To assess the efficacy of slow release oral morphine (SROM) as a treatment for opioid use disorder (OUD). Design Systematic review and meta-analysis of randomised controlled trials (RCTs). Data sources Three electronic databases were searched through 1 May 2018: the Cochrane Central Register of Controlled Trials, MEDLINE and EMBASE. We also searched the following electronic registers for ongoing trials: ClinicalTrials.gov, WHO International Clinical Trials Registry Platform, Current Controlled Trials and the EU Clinical Trials Register. Eligibility criteria for selecting studies We included RCTs of all durations, assessing the effect of SROM on measures of treatment retention, heroin use and craving in adults who met the diagnostic criteria for OUD. Data extraction and synthesis Two independent reviewers extracted data and assessed risk of bias. Data were pooled using the random-effects model and expressed as risk ratios (RRs) or mean differences with 95% CIs. Heterogeneity was assessed (χ 2 statistic) and quantified (I 2 statistic) and a sensitivity analysis was undertaken to assess the impact of particular high-risk trials. Results Among 1315 records screened and four studies reviewed, four unique randomised trials met the inclusion criteria (n=471), and compared SROM with methadone. In the meta-analysis, we observed no significant differences between SROM and methadone in improving treatment retention ( RR=0.98; 95%CI: 0.94 to 1.02, p=0.34) and heroin use (RR=0.96; 95% CI: 0.61 to 1.52, p=0.86). Craving data was not amenable to meta-analysis. Available data implied no differences in adverse events, heroin, cocaine or benzodiazepine use. Conclusions Meta-analysis of existing randomised trials suggests SROM may be generally equal to methadone in retaining patients in treatment and reducing heroin use while potentially resulting in less craving. The methodological quality of the included RCTs was low-to-moderate.
Association of Polymorphisms in Pharmacogenetic Candidate Genes (OPRD1, GAL, ABCB1, OPRM1) with Opioid Dependence in European Population: A Case-Control Study Beate Beer, Robert Erb, Marion Pavlic, Hanno Ulmer, Salvatore Giacomuzzi, Yvonne Riemer, Herbert Oberacher Plos One, 2013 It is becoming increasingly evident that genetic variants contribute to the development of opioid addiction. An elucidation of these genetic factors is crucial for a better understanding of this chronic disease and may help to develop novel therapeutic strategies. In recent years, several candidate genes were implicated in opioid dependence. However, most study findings have not been replicated and additional studies are required before reported associations can be considered robust. Thus, the major objective of this study was to replicate earlier findings and to identify new genetic polymorphisms contributing to the individual susceptibility to opioid addiction, respectively. Therefore, a candidate gene association study was conducted including 142 well-phenotyped long-term opioid addicts undergoing opioid maintenance therapy and 142 well-matched healthy controls. In both study groups, 24 single nucleotide polymorphisms predominantly located in pharmacogenetic candidate genes have been genotyped using an accurate mass spectrometry based method. The most significant associations with opioid addiction (remaining significant after adjustment for multiple testing) were observed for the rs948854 SNP in the galanin gene (GAL, p = 0.001) and the rs2236861 SNP in the delta opioid receptor gene (OPRD1, p = 0.001). Moreover, an association of the ATP binding cassette transporter 1 (ABCB1) variant rs1045642 and the Mu Opioid receptor (OPRM1) variant rs9479757 with opioid addiction was observed. The present study provides further support for a contribution of GAL and OPRD1 variants to the development of opioid addiction. Furthermore, our results indicate a potential contribution of OPRM1 and ABCB1 SNPs to the development of this chronic relapsing disease. Therefore it seems important that these genes are addressed in further addiction related studies.
A semi-qualitative analysis regarding the properties of buprenorphine-/naloxone compounds and their acceptance as an alternative in maintenance treatment S. Giacomuzzi, K. Garber, Y. Riemer Suchttherapie, 2012 Buprenorphin-/Naloxon-Kombinationspräparate wurden entwickelt um die Substitution mit Buprenorphin sicherer zu gestalten. Bis dato gestalten sich diese Anstrengungen als weniger fruchtbar und die Akzeptanz dieser neuen Präparatgruppe erscheint gegenüber der klassischen Buprenorphindarreichung vermindert. Die individuelle Wirkwahrnehmung der Substanzen in der Opioidsubstitution kann schwerlich allein mit empirischen Methoden quantifiziert werden. Diese ist jedoch von fundamentaler Bedeutung für die individuelle Akzeptanz seitens des Klienten. Im Folgenden wird ein Fallbeispiel geschildert, welches die individuelle Wirkwahrnehmung bei Einnahme von Buprenorphin/Naloxon-Kombinationspräparaten beschreibt.
Psychosocial workload and stress in the workers representative Martin Rabe, Salvatore Giacomuzzi, Matthias Nübling BMC Public Health, 2012 Compared to the reference groups, works council members perceive the psychosocial demands of working life as more exhausting for the majority of aspects. This allows several conclusions. One reason may be the extended tasks employee representatives face, an other may be that the education of most works council members does not seem appropriate to the high demands of their managerial and executive tasks.
Outlines of interdisciplinary addiction research given by the example of medical imaging with PET, SPECT and fMRI regarding effects of psychotropic substances Neuropsychiatrie, 2010
Impact of slow-release oral morphine on drug abusing habits in Austria Neuropsychiatrie, 2010
Applications of breath gas analysis in addiction medicine - Preliminary results S. M. Giacomuzzi, Y. Riemer, M. Pavlic, A. Schmid, H. Hinterhuber, A. Amann Substance Use and Misuse, 2009 Drug abuse1 is a common phenomenon which virtually confronts all countries in Europe and has also been a major public health issue over the past decades. Monitoring of prescribed and nonprescribed ...
Self-efficacy expectation and additional substance use related to employment status of patients in opioid substitution management Neuropsychiatrie, 2006
Three years of experience with buprenorphine (Subutex ®) substitution: The substitution model of the Innsbruck University Hospital and the changeover from high-dose methadone to buprenorphine (Subutex ®) Suchtmedizin in Forschung Und Praxis, 2002
The ACOnet (Austrian Academic Computer Network) is data carrier for teleradiological consultations Rofo Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Neuen Bildgebenden Verfahren, 1998
Downhill varices in struma permagna and unilateral hypoplasia of the internal jugular vein Aktuelle Radiologie, 1996
Dose reduction in computed tomography by means of a new scanning procedure Aktuelle Radiologie, 1996
Use of a PC-based network for quality assurance of film processing Aktuelle Radiologie, 1996
Establishment of an emergency CT service by means of teleradiology Rofo Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Neuen Bildgebenden Verfahren, 1996
