Vitor Fernandes Moreno

@.fob.usp.br

School of Dentistry - University of São Paulo
University of São Paulo

Vitor Fernandes Moreno

RESEARCH, TEACHING, or OTHER INTERESTS

Materials Chemistry, Organic Chemistry, Polymers and Plastics, Biomaterials
8

Scopus Publications

115

Scholar Citations

5

Scholar h-index

2

Scholar i10-index

Scopus Publications

  • Radical and Environmentally Friendly Route to Poly(fullerene)s Incorporating C60, C70, and PCBM
    Eleftheria Batagianni, Olivier Doat, Nicolas Elissalt, Douvotsu Elisa Moungadji Bouassa, Jessyka Carolina Bittencourt, Gabriel Cardoso Goncalves, Vitor Fernandes Moreno, João Victor Morais Lima, Gabriel Leonardo Nogueira, Lucas Jorge Affonço, João Vitor Paulin, Silvia Leticia Fernandes, Renato Ferranti, Abdel Khoukh, Luiz Carlos da Silva Filho, Deuber Lincon da Silva Agostini, Clarissa de Almeida Olivati, Patricia Targon Campana, Carlos F. O. Graeff, Didier Bégué, Roger C. Hiorns
    Macromolecules, 2025
    For the first time, this article shows how it is possible to make well-soluble poly(fullerene xylene)s using potassium iodide and in low amounts of solvents. This new method makes it possible to use low-cost, environmentally friendly starting materials, nonchlorinated solvents, and main-chain C60, PCBM, and for the first time, C70, polymers. The reaction can even be performed in the presence of water, further increasing its environmental friendliness. Specifically, a dibromomethylated comonomer, such as 2,5-bis(bromomethyl)-1,4-bis(oxidodecyl)benzene, is reacted with potassium iodide, 18-crown-6, and fullerene in refluxing toluene to yield highly modular alternating copolymers. Model reactions show that polymerization works by the transformation of methylene bromides into methylene iodides, which then disintegrate to make methylene radicals that react with the fullerenes. The radical nature of this new iodine-mediated polymerization (IMP) is confirmed by its sensitivity to the radical trap (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO). The comonomers add in pairs to the fullerene to yield linear chains. NMR and UV–visible spectroscopy along with quantum calculations suggest that most bonds to the fullerene are in 1,4-positions on the same hexagonal ring, however, a minority of C60-methylene bonds are situated several bonds apart on the fullerene, suggesting that iodine “walks” across the fullerene surface. This new polymerization of fullerene, without its reliance on copper and chlorinated solvents and ability to work in the presence of water, makes it of wide use for materials for optoelectronics and medicine where even trace impurities can impact heavily on material properties.
  • Novel quinoline photoinitiators for dimethacrylate monomer photopolymerization under UV and blue light
    Vitor Fernandes Moreno, Bruno Hori Barboza, Lucas Michelão Martins, Caroline Gaglieri, Gilbert Bannach, Augusto Batagin-Neto, Luiz Carlos da Silva-Filho
    European Polymer Journal, 2024
  • Bronsted Acid Mediated Facile Greener Multicomponent Synthesis of 2,4-Diaryl-quinoline Derivatives in Water
    Lucas Michelão Martins, Vitor Fernandes Moreno, Ilana Sganzerla Rosário, Carlos Frederico de Oliveira Graeff, Luiz Carlos Silva Filho
    Orbital, 2022
    Quinolines are an important class of natural and synthetic products, with several biological activity and applications in medicine and electronics. In this work we present a greener method of synthesis of 2,4-diaryl-quinoline derivatives by an easy one-pot multicomponent reaction between aniline derivatives, aldehyde derivatives and phenylacetylene in water, with hydrochloric acid as promoter. With this method we could synthesize several compounds with good yield and reaction time, including new alkylamino-containing 2,4-diaryl-quinoline derivatives that could not be synthesized with niobium pentachloride catalyst in similar conditions. DOI: http://dx.doi.org/10.17807/orbital.v14i1.1689
  • Heterocyclic compounds as antiviral drugs: Synthesis, structure–activity relationship and traditional applications
    Giovanny Carvalho dos Santos, Lucas Michelão Martins, Bruna Andressa Bregadiolli, Vitor Fernandes Moreno, Luiz Carlos da Silva‐Filho, Bruno Henrique Sacoman Torquato da Silva
    Journal of Heterocyclic Chemistry, 2021
    A virus outbreak challenges the economic, medical, and public health infrastructure worldwide. More than one virus capable of triggering diseases have been identified per year since 1972, which requires the development of new ways of treatment and prevention, however, such processes are not rapid and easy. With the pandemic scenario experienced since early 2020, several drugs with well‐known purposes have gained prominence, due to speculation of their use in the treatment against the new coronavirus. Among the main drugs studied, the vast majority contain a heterocyclic structure. In this review, we presented the traditional and efficient synthesis of 15 drugs that have been studied for the COVID‐19 treatment, containing in their structure heterocycles like indole, quinoline, pyrimidone, tetrahydrofuran, pyrrolidine, triazole, pyridazine, pyrazole, pyrrolopyrimidine, azetidine, pyrrolotriazine, pyrazine, tetrahydropyran, benzofuran, spiroketal, and thiazole. Furthermore, we have shown the original applications, as well as their structure–activity relationship and what is their situation as a drug candidate against COVID‐19. Thus, the objective was to consolidate the main synthetic and pharmacological aspects involving clinically developed heterocycles that at some point were presented as promising against SARS‐CoV‐2.
  • Environmental effects in nitroquinoline derivatives solutions: Solvatochromism, acid-base effect and ion-sensor investigation
    Giovanny Carvalho dos Santos, Julia Lopes Rodrigues, Vitor Fernandes Moreno, Luiz Carlos da Silva-Filho
    Journal of Molecular Structure, 2021
  • NbCl5 Promoted the Efficient Synthesis of Phthalein Derivatives: Optical Characterization and Solvatochromic Effect
    Vitor Fernandes Moreno, Giovanny Carvalho dos Santos, Gyordanna Mayara Gaspar da Costa, Marcelo Henrique Ayala Gomes, Luiz Carlos da Silva‐Filho
    Journal of Heterocyclic Chemistry, 2019
    Organic dyes derived from phthaleins have a large number of industrial applications and can be synthesized using a Lewis acid by Friedel–Crafts acylation, followed by an addition reaction to the carbonyl compound. This work aims to investigate the use of NbCl5 as a catalyst for the acylation reaction. The behavior of the phthalein derivatives in several solvents and when subjected to different pH conditions was studied. These compounds showed a color‐changing effect depending on the pH and solvent, making them useful for applications as indicators. The phthaleins change their conformations depending on the condition of the medium. Photophysical studies of these compounds were carried out through their UV–Vis absorption spectra. Here, we show the umbrella‐like conformation change of phthalein derivatives that depend on the solvent and the pH of the medium.
  • Heterocyclic anthrazoline derivatives: A critical review
    Giovanny Carvalho dos Santos, Vitor Fernandes Moreno, Bruno Henrique Sacoman Torquato da Silva, Luiz Carlos da Silva-Filho
    New Journal of Chemistry, 2019
    The anthrazolinic core is an important building block for several applications, especially those depending on the effect of light.
  • NbCl5 a multifunctional reagent for the synthesis of new halogenated aminoquinoline compounds through innovative one-pot reaction and the acidochromism effect
    Giovanny Carvalho dos Santos, Vitor Fernandes Moreno, Paula Beatriz Oshiro, Luiz Carlos da Silva-Filho
    Tetrahedron, 2018

RECENT SCHOLAR PUBLICATIONS

  • Radical and Environmentally Friendly Route to Poly(fullerene)s Incorporating C60, C70, and PCBM
    Macromolecules, https://doi.org/10.1021/acs.macromol.4c0 , 2025
    2025.0
    Citations: 2
  • New quinoline-based photoinitiators for polymerization applied to dental resins
    VF Moreno, LC da Silva Filho, AY Furuse
    18° Brazilian Polymer Conference, 1604 , 2025
    2025.0
  • Aplicação de derivados quinolínicos na síntese de polímeros
    VF Moreno
    Universidade Estadual Paulista (Unesp) , 2024
    2024.0
  • Novel quinoline photoinitiators for dimethacrylate monomer photopolymerization under UV and blue light
    VF Moreno, BH Barboza, LM Martins, C Gaglieri, G Bannach, ...
    European Polymer Journal 218, 113331 , 2024
    2024.0
    Citations: 9
  • Compostos de nióbio: uma importante ferramenta na síntese de compostos heterocíclicos
    LCSF Vitor Fernandes Moreno, Giovanny Carvalho dos Santos
    Química orgânica sintética: Brasil 2022 3, 417-427 , 2022
    2022.0
  • Bronsted Acid Mediated Facile Greener Multicomponent Synthesis of 2, 4-Diaryl-quinoline Derivatives in Water
    LM Martins, VF Moreno, IS Rosário, CF de Oliveira Graeff, ...
    Orbital: The Electronic Journal of Chemistry, 1-9 , 2022
    2022.0
    Citations: 5
  • Heterocyclic compounds as antiviral drugs: Synthesis, structure–activity relationship and traditional applications
    GC dos Santos, LM Martins, BA Bregadiolli, VF Moreno, LC da Silva‐Filho, ...
    Journal of Heterocyclic Chemistry 58 (12), 2226-2260 , 2021
    2021.0
    Citations: 61
  • Heterocyclic compounds as antiviral drugs: synthesis, structure-activity relationship and traditional applications
    GC Santos, LM Martins, BA Bregadiolli, VF Moreno, LC Silva-Filho, ...
    Wiley , 2021
    2021.0
    Citations: 2
  • Environmental effects in nitroquinoline derivatives solutions: Solvatochromism, acid-base effect and ion-sensor investigation
    GC dos Santos, JL Rodrigues, VF Moreno, LC da Silva-Filho
    Journal of Molecular Structure 1235, 130260 , 2021
    2021.0
    Citations: 3
  • Bronsted Acid Mediated Facile Greener Multicomponent Synthesis of 2, 4-Diaryl-quinoline Derivatives in Water
    LM Martins, VF Moreno, IS Rosario, CF de Oliveira Graeff, LC Silva Filho
    ORBITAL-THE ELECTRONIC JOURNAL OF CHEMISTRY 14 (1), 9 , 2021
    2021.0
    Citations: 2
  • LC daSilva-Filho
    GC dos Santos, JL Rodrigues, VF Moreno
    J. Mol. Struct 1235, 130260 , 2021
    2021.0
    Citations: 5
  • NbCl 5 Promoted the Efficient Synthesis of Phthalein Derivatives: Optical Characterization and Solvatochromic Effect
    VF Moreno, GC dos Santos, GMG da Costa, MHA Gomes, LC Silva‐Filho
    Journal of Heterocyclic Chemistry 56 (10), 2811-2821 , 2019
    2019.0
    Citations: 4
  • Síntese e aplicação de derivados quinolínicos como inibidores de corrosão em aço inoxidável AISI 430
    VF Moreno
    Universidade Estadual Paulista (Unesp) , 2019
    2019.0
    Citations: 1
  • rsc. li/njc
    GC dos Santos, VF Moreno, BHST da Silva, LC da Silva-Filho, N Juneja, ...
    New J. Chem 43, 18433 , 2019
    2019.0
  • Heterocyclic anthrazoline derivatives: a critical review
    GC Dos Santos, VF Moreno, BHST Da Silva, LC da Silva-Filho
    New Journal of Chemistry 43 (47), 18415-18432 , 2019
    2019.0
    Citations: 8
  • NbCl5 a multifunctional reagent for the synthesis of new halogenated aminoquinoline compounds through innovative one-pot reaction and the acidochromism effect
    GC dos Santos, VF Moreno, PB Oshiro, LC da Silva-Filho
    Tetrahedron 74 (42), 6144-6149 , 2018
    2018.0
    Citations: 13
  • Estudos sobre o uso do pentacloreto de Nióbio, como ácido de Lewis, na síntese de corantes orgânicos derivados de ftaleínas
    VF Moreno
    Universidade Estadual Paulista (Unesp) , 2017
    2017.0
  • Positional isomerism in nitro-quinoline photoinitiators: exploring the effects of hydroxyl and methacrylate substituents on the photopolymerization of advanced composite resins
    VF Moreno, LC Silva-Filho, AY Furuse
    Available at SSRN 6561760 , 0
  • Heterocyclic compounds as antiviral drugs: synthesis, structure-activity
    GC dos Santos, LM Martins, BA Bregadiolli, VF Moreno, LC da Silva-Filho, ...
  • Synthesis and photopolymerization of quinoline derivatives containing methacrylate group with potential application in biomaterials
    IS Rosário, VF Moreno, LC da Silva Filho

MOST CITED SCHOLAR PUBLICATIONS

  • Heterocyclic compounds as antiviral drugs: Synthesis, structure–activity relationship and traditional applications
    GC dos Santos, LM Martins, BA Bregadiolli, VF Moreno, LC da Silva‐Filho, ...
    Journal of Heterocyclic Chemistry 58 (12), 2226-2260 , 2021
    2021.0
    Citations: 61
  • NbCl5 a multifunctional reagent for the synthesis of new halogenated aminoquinoline compounds through innovative one-pot reaction and the acidochromism effect
    GC dos Santos, VF Moreno, PB Oshiro, LC da Silva-Filho
    Tetrahedron 74 (42), 6144-6149 , 2018
    2018.0
    Citations: 13
  • Novel quinoline photoinitiators for dimethacrylate monomer photopolymerization under UV and blue light
    VF Moreno, BH Barboza, LM Martins, C Gaglieri, G Bannach, ...
    European Polymer Journal 218, 113331 , 2024
    2024.0
    Citations: 9
  • Heterocyclic anthrazoline derivatives: a critical review
    GC Dos Santos, VF Moreno, BHST Da Silva, LC da Silva-Filho
    New Journal of Chemistry 43 (47), 18415-18432 , 2019
    2019.0
    Citations: 8
  • Bronsted Acid Mediated Facile Greener Multicomponent Synthesis of 2, 4-Diaryl-quinoline Derivatives in Water
    LM Martins, VF Moreno, IS Rosário, CF de Oliveira Graeff, ...
    Orbital: The Electronic Journal of Chemistry, 1-9 , 2022
    2022.0
    Citations: 5
  • LC daSilva-Filho
    GC dos Santos, JL Rodrigues, VF Moreno
    J. Mol. Struct 1235, 130260 , 2021
    2021.0
    Citations: 5
  • NbCl 5 Promoted the Efficient Synthesis of Phthalein Derivatives: Optical Characterization and Solvatochromic Effect
    VF Moreno, GC dos Santos, GMG da Costa, MHA Gomes, LC Silva‐Filho
    Journal of Heterocyclic Chemistry 56 (10), 2811-2821 , 2019
    2019.0
    Citations: 4
  • Environmental effects in nitroquinoline derivatives solutions: Solvatochromism, acid-base effect and ion-sensor investigation
    GC dos Santos, JL Rodrigues, VF Moreno, LC da Silva-Filho
    Journal of Molecular Structure 1235, 130260 , 2021
    2021.0
    Citations: 3
  • Radical and Environmentally Friendly Route to Poly(fullerene)s Incorporating C60, C70, and PCBM
    Macromolecules, https://doi.org/10.1021/acs.macromol.4c0 , 2025
    2025.0
    Citations: 2
  • Heterocyclic compounds as antiviral drugs: synthesis, structure-activity relationship and traditional applications
    GC Santos, LM Martins, BA Bregadiolli, VF Moreno, LC Silva-Filho, ...
    Wiley , 2021
    2021.0
    Citations: 2
  • Bronsted Acid Mediated Facile Greener Multicomponent Synthesis of 2, 4-Diaryl-quinoline Derivatives in Water
    LM Martins, VF Moreno, IS Rosario, CF de Oliveira Graeff, LC Silva Filho
    ORBITAL-THE ELECTRONIC JOURNAL OF CHEMISTRY 14 (1), 9 , 2021
    2021.0
    Citations: 2
  • Síntese e aplicação de derivados quinolínicos como inibidores de corrosão em aço inoxidável AISI 430
    VF Moreno
    Universidade Estadual Paulista (Unesp) , 2019
    2019.0
    Citations: 1
  • New quinoline-based photoinitiators for polymerization applied to dental resins
    VF Moreno, LC da Silva Filho, AY Furuse
    18° Brazilian Polymer Conference, 1604 , 2025
    2025.0
  • Aplicação de derivados quinolínicos na síntese de polímeros
    VF Moreno
    Universidade Estadual Paulista (Unesp) , 2024
    2024.0
  • Compostos de nióbio: uma importante ferramenta na síntese de compostos heterocíclicos
    LCSF Vitor Fernandes Moreno, Giovanny Carvalho dos Santos
    Química orgânica sintética: Brasil 2022 3, 417-427 , 2022
    2022.0
  • rsc. li/njc
    GC dos Santos, VF Moreno, BHST da Silva, LC da Silva-Filho, N Juneja, ...
    New J. Chem 43, 18433 , 2019
    2019.0
  • Estudos sobre o uso do pentacloreto de Nióbio, como ácido de Lewis, na síntese de corantes orgânicos derivados de ftaleínas
    VF Moreno
    Universidade Estadual Paulista (Unesp) , 2017
    2017.0
  • Positional isomerism in nitro-quinoline photoinitiators: exploring the effects of hydroxyl and methacrylate substituents on the photopolymerization of advanced composite resins
    VF Moreno, LC Silva-Filho, AY Furuse
    Available at SSRN 6561760 , 0
  • Heterocyclic compounds as antiviral drugs: synthesis, structure-activity
    GC dos Santos, LM Martins, BA Bregadiolli, VF Moreno, LC da Silva-Filho, ...
  • Synthesis and photopolymerization of quinoline derivatives containing methacrylate group with potential application in biomaterials
    IS Rosário, VF Moreno, LC da Silva Filho

GRANT DETAILS

FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO (FAPESP), Brazil
Grant number: 2024/14443-6

Industry, Institute, or Organisation Collaboration

Universidade de São Paulo (USP), Brazil; Universidade Estadual Paulista (UNESP), Brazil and Université de Pau et des Pays de l'Adour (UPPA), France.

INDUSTRY EXPERIENCE

Amyris | Biotechnology Company