baris kaya

@camsakurasehir.saglik.gov.tr

Başakşehir Çam and Sakura City Hospital
Başakşehir Çam and Sakura City Hospital

baris kaya


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https://researchid.co/mdbariskaya
Barış Kaya, MD, Assoc. Prof., is an obstetrician-gynecologist at Başakşehir Çam & Sakura City Hospital specializing in advanced laparoscopic surgery, deep infiltrating endometriosis, and complex hysterectomy techniques. He has published impactful clinical studies on postpartum hemorrhage, particularly on the use of the Bakri balloon and other uterus-sparing approaches, contributing to safer and fertility-preserving management strategies. Beyond his clinical work, he leads a TÜBİTAK-supported experimental research project on uterus transplantation using an animal model, aiming to expand future fertility options for patients with absolute uterine factor infertility.

EDUCATION

MD – Istanbul University, Istanbul Faculty of Medicine
1996–2003

Residency in Obstetrics and Gynecology – Ege Maternity and Research Hospital, İzmir
2003–2008

Academic Training & Faculty Development – Near East University, Faculty of Medicine
2013–2019
(Assistant Professor; clinical research, teaching, and minimally invasive surgery training)

Advanced Academic Training – Yeditepe University, Faculty of Medicine
2019–2020
(Clinical academic work, surgical training, and research activity)

Associate Professor (Doçentlik) – Obstetrics and Gynecology
2018
(Interuniversity Board, Türkiye)

RESEARCH, TEACHING, or OTHER INTERESTS

Obstetrics and Gynecology
30

Scopus Publications

Scopus Publications

  • Evaluation of brain pain centers in endometriosis-associated chronic pelvic pain: Retrospective insights into central sensitization using a novel magnetic resonance imaging technique
    Isin Erdogan, Baris Kaya, Serdar Arslan, Ahmet Oz, Koray Gok, Abdullah Tuten, Abdullah Serdar Acikgoz
    International Journal of Gynecology and Obstetrics, 2026
    Objective To investigate alterations in brain pain‐processing networks using resting‐state functional magnetic resonance imaging (rs‐fMRI) in women with endometriosis‐associated chronic pelvic pain and to evaluate neurobiological evidence of central sensitization relevant to clinical management. Methods This retrospective study included 30 women aged 18–45 years: 10 with deep infiltrating endometriosis (DIE) and chronic pelvic pain, 10 with ovarian endometriomas without pain, and 10 healthy controls. rs‐fMRI data were analyzed using the SPM12 and the CONN toolbox. Seed‐to‐voxel functional connectivity analyses focused on predefined pain‐related brain regions. Between‐group differences were assessed using two‐sample t tests with family‐wise error (FWE) correction. Results Compared with controls, women with DIE and chronic pelvic pain demonstrated significantly increased connectivity between the amygdala and the right frontal pole (FWE‐corrected P = 0.012 and 0.044), left paracingulate gyrus (FWE‐corrected P = 0.036), right frontal operculum cortex (FWE‐corrected P = 0.040), and anterior cingulate gyrus (FWE‐corrected P = 0.044). Increased con was also observed between the posterior cingulate gyrus and the precuneus cortex (FWE‐corrected P = 0.002), whereas decreased connectivity was detected between the anterior cingulate gyrus and the posterior left middle temporal gyrus (FWE‐corrected P = 0.002). No significant differences were found in patients with ovarian endometriomas without pain. Conclusion Endometriosis‐associated chronic pelvic pain is associated with altered connectivity within key pain modulation networks, supporting central sensitization. Persistent pelvic pain may therefore reflect maladaptive central pain processing in addition to peripheral pathology. Recognition of these neurofunctional alterations may improve understanding of treatment‐resistant pain and support earlier multidisciplinary and individualized management strategies.
  • Serum heat shock protein 90 alpha levels in mild and severe preeclampsia
    Kübra Hamzaoğlu Canbolat, Abdullah Serdar Açıkgöz, Koray Gök, Abdullah Tüten, Barış Kaya, et al.
    Revista Da Associacao Medica Brasileira, 2025
    OBJECTIVE: The aim of the study was to assess serum heat shock protein 90 alpha levels as a marker in preeclampsia. METHODS: This cross-sectional study was carried out in 2015 at Istanbul Cerrahpasa University, University Hospital for Obstetrics and Gynecology. The mild (n=60) and severe (n=60) preeclampsia groups were compared with healhty, uncomplicated pregnancies, matched for gestational age within ±1 week (n=120). The main inclusion criteria were women between 18 and 40 years old who had a singleton pregnancy. Pregnant women with any known medical diseases (chronic hypertension, renal diseases, inflammatory diseases, or infections), regular contractions with cervical changes, and premature rupture of membranes were excluded from the study. RESULTS: Median serum heat shock protein 90 alpha was significantly elevated in mild preeclamptic women compared to women in the gestational age-matched control group [3.41 vs. 2.62 ng/mL, p<0.001]. The mean serum heat shock protein 90 alpha levels were significantly elevated in the severe preeclampsia group compared to their gestational age-matched control group [3.94 vs. 2.55 ng/mL, p<0.001]. Mean serum heat shock protein 90 alpha levels were comparable between the mild and severe preeclampsia groups (3.41 vs. 3.94 ng/mL, p=0.407) and mild early-onset and severe early-onset groups (p=0.104). Serum heat shock protein 90 alpha showed a weak positive correlation with both systolic and diastolic arterial blood pressure. CONCLUSION: Heat shock protein 90 alpha level was elevated in preeclamptic patients. The level of heat shock protein 90 alpha in serum may be suitable for evaluating endothelial dysfunction.
  • Evaluation of serum levels of soluble vascular endothelial (sVE)-Cadherin in early- and late-onset preeclampsia serum sVE-Cadherin levels in preeclampsia
    Abdullah Serdar Acikgöz, Koray Gök, Abdullah Tüten, Barış Kaya, Kübra Hamzaoğlu, Tuğba Kolomuç Gayretli, Eduard Malik, Onur Güralp
    Journal of Maternal Fetal and Neonatal Medicine, 2024
    OBJECTIVE: Endothelial dysfunction is a major feature of preeclampsia. sVE-cadherin plays a role in the preservation and regulation of the endothelial barrier. For that reason, to evaluation of sVE-cadherin may help elucidate the disease pathophysiology of preeclampsia. METHODS: = 60) preeclampsia were compared with 120 gestational-age (GA)-matched (±1 week) uncomplicated pregnancies. The venous blood sampling was performed upon preeclampsia diagnosis prior to the onset of the labor in the preeclampsia group and the matching (±1 week) pregnancy week in the control group. Demographic and biochemical parameters were evaluated. RESULTS: < 0.001) after correction for GA. Serum sVE-Cadherin positively correlated with systolic and diastolic blood pressure and a negative correlation with gestational age at sampling. CONCLUSION: The serum level of sVE-Cadherin was higher in women with preeclampsia than that of GA-matched healthy pregnant women, in women with EOPE compared to that of LOPE. sVE-Cadherin is an important marker in early-onset pre-eclampsia with severe clinical findings.
  • Can the Pfannenstiel skin incision length be adjusted according to the fetal head during elective cesarean delivery?
    Baris Kaya, Ozlen Emekci Ozay, Ali Cenk Ozay, Abdullah Tüten
    Frontiers in Surgery, 2023
    ObjectiveThe study aims to determine whether the Pfannenstiel skin incision can be adjusted according to the fetal head's occipitofrontal diameter (OFD) during primary cesarean delivery.BackgroundEligible 114 nulliparous women delivered at term by cesarean section in which Pfannenstiel skin incision was performed according to the OFD of the fetal head between June 2017 and September 2021 were included. Excluded cases were non-vertex presentations, all emergency cesarean sections, severe preeclampsia, women in an active phase of the first stage of labor and second stage of labor, placenta previa and low-lying placenta, multiple pregnancies, and uncontrolled gestational diabetes mellitus.ResultsAmong 114 eligible nulliparous women, the mean OFD was 116.1 ± 7.2 (99–138) mm, and the measurement of the Pfannenstiel skin incision length, which was performed according to the OFD was found to be 122.8 ± 9.2 (100–155) mm. The difference between OFD and Pfannenstiel incision kept remained within 10 mm in 90 (82.5.2%), 10–20 mm in 17 (15.5%), and more than 20 mm in two women (1.8%). This technique was successful in 109 (95.6%) out of 114 women without extending the skin incision. In five women, skin incision needed to be extended up to 38 mm. In 10 women (8.7%), the rectus abdominis muscle was cut partially to deliver the fetal head. The mean fetal umbilical artery pH was 7.33 ± 0.05. No neonatal hypoxia was encountered in the study.ConclusionPfannenstiel skin incision can be adjusted according to the OFD with minimal margins of error. This technique may provide better cosmetic results by avoiding unnecessarily prolonged incisions with similar newborn outcomes.Clinical Trial RegistrationClinicaltrials.gov, identifier [NCT05632796].
  • Non-invasive diagnosis of endometriosis and moderate-severe endometriosis with serum CA125, endocan, YKL-40, and copeptin quadruple panel
    Onur Guralp, Baris Kaya, Nevin Tüten, Mine Kucur, Eduard Malik, Abdullah Tüten
    Journal of Obstetrics and Gynaecology, 2021
    Considering the complex pathogenesis of endometriosis, which is associated with many cellular or molecular processes, such as proliferation, angiogenesis, inflammation, we evaluated the diagnostic value of a quadruple panel of serum markers CA125, endocan, YKL-40 and copeptin, for the prediction of endometriosis and moderate – severe endometriosis. Seventy women with endometriosis and 70 women without endometriosis were evaluated. Serum CA125, endocan, copeptin and YKL-40 levels were significantly increased in women with endometriosis compared to the women without endometriosis and in the minimal – mild endometriosis group compared to the no-endometriosis group. YKL-40, endocan and copeptin levels were significantly increased in the moderate – severe endometriosis group compared to the mild –moderate endometriosis group but the difference in CA125 levels remained non-significant. The quadruple panel score had an AUC of 0.954, a sensitivity of 96.5% and specificity of 84.6% for prediction of moderate – severe endometriosis. Zero or one positive marker had a sensitivity of 91.4% and specificity of 88.57% to rule out endometriosis. In conclusion, a quadruple panel of serum markers-CA125, endocan, YKL-40, and copeptin may be beneficial for the diagnosis of endometriosis and especially moderate – severe endometriosis. Further studies are needed to prove the efficacy of this panel.Impact statementWhat is already known on this subject? Many serum markers including CA125 have been investigated so far and suggested to be associated with endometriosis. However, none of these markers is sensitive and specific enough to diagnose endometriosis.What do the results of this study add? A quadruple panel score (CA125, endocan, YKL-4 and copeptin) had an AUC of 0.954, a sensitivity of 96.5% and specificity of 84.6% for prediction of moderate – severe endometriosis.What are the implications of these findings for clinical practice and/or further research? A high score may be beneficial to warn the surgeon about the risk of moderate to severe endometriosis if the patient will be operated anyway. A negative test of the quadruple panel may show high odds that there is no endometriosis which may prevent unnecessary surgery.
  • Temporary clamping of bilateral common iliac artery during cesarean hysterectomy for the management of placenta
    Seyhun Sucu, Huseyin Çaglayan Ozcan, Mesut Misirlioglu, Onur Guralp, Baris Kaya
    European Journal of Obstetrics and Gynecology and Reproductive Biology, 2020
  • Paraoxonase 1 (PON1) Q192R and L55M polymorphisms, lipid profile, lipid peroxidation and lipoprotein-a levels in Turkish patients with pregnancy-related disorders
    Birsen Aydemir, F. Behice Serinkan Cinemre, Hakan Cinemre, Abdullah Tüten, M. Aytaç Yüksel, Nevin Yılmaz, Barıs Kaya, Nermin Akdemir, Elif Erdogan, Rıza Madazlı
    Gynecological Endocrinology, 2019
    The aim of this study was to investigate the role of PON1Q192R and L55M single nucleotide polymorphisms(SNPs) and its association with the maternal levels of lipid parameters in gestational diabetes mellitus(GDM) and preeclampsia(PE). Ninety-nine pregnant with GDM, 97 pregnant with PE and 98 healthy pregnant were included in the study. No statistically significant difference was observed in the alleles or in the genotypes frequencies of SNPs between groups. In GDM patients, total cholesterol was higher in MM genotype of L55M gene (p < .05); Lp(a) were lower in LM genotype of the gene compared to their respective control (p < .05). In PE, HDL-C levels were higher in LM genotype (p < .05); LDL-C levels were lower in MM genotype of the gene compared to their respective control (p < .05). In PE patients, malondialdehyde(MDA) were higher in QQ genotype compared to their respective control (p < .05). Triglyceride levels were higher in PE patients with QR genotype compared with GDM patients with QR genotype (p < .05). Our results indicated that lipid profiles, Lp(a) and MDA levels showed significant differences in GDM and PE pregnants. These findings support the importance of the lipid profile, oxidized lipid and Lp(a) in different genotypes of L55M and Q192R in Turkish pregnant women with PE/GDM suggesting their roles in etiopathogenesis in these pregnancy-related disorders.
  • Hysteroscopic management of cervical pregnancy: Case series and review of the literature
    Vasilios Tanos, Sayed ElAkhras, Baris Kaya
    Journal of Gynecology Obstetrics and Human Reproduction, 2019
  • Evaluation of the prevalence of sexually transmitted bacterial pathogens in northern cyprus by nucleic acid amplification tests, and investigation of the relationship between these pathogens and cervicitis
    Onur Güralp, Ayşegül Bostancı, Esra Özerkman Başaran, Meike Schild-Suhren, Barış Kaya
    Turkish Journal of Obstetrics and Gynecology, 2019
    OBJECTIVE: in women via multiplex-polymerase chain reaction (PCR)-deoxyribonucleic acid (DNA). MATERIALS AND METHODS: Cervical swabs of 273 women in reproductive age who underwent gynecologic examination in our outpatient clinic were evaluated using the multiplex-PCR-DNA method. The presence of cervicitis, contraceptive methods, marital status, and the number of partners were evaluated. RESULTS: , which are often associated with cervicitis, were comparable in women with and without cervicitis. CONCLUSION: .
  • Does ligation of internal iliac artery for postpartum hemorrhage affect clitoral artery blood flow and postpartum sexual functions?
    B. Kaya, B. Usluogullari, N. Yurttutan, M.H. Sahan, O. Güralp, E. Malik
    European Journal of Obstetrics and Gynecology and Reproductive Biology, 2017
  • Maternal serum autotaxin levels in early- and late-onset preeclampsia
    Hakan Erenel, Nevin Yilmaz, Tayfur Cift, Berk Bulut, Isik Sozen, Berna Aslan Cetin, Altay Gezer, Hakan Ekmekci, Baris Kaya, Abdullah Tuten
    Hypertension in Pregnancy, 2017
  • Is there yet a role for internal iliac artery ligation in obstetric hemorrhage with the current gain in popularity of other uterus sparing techniques?
    Baris Kaya, Zeki Damarer, Korkut Daglar, Orhan Unal, Amr Soliman, Onur Guralp
    Journal of Maternal Fetal and Neonatal Medicine, 2017
  • Surgical treatment of uterine atony: An assessment of final year obstetrics and gynecology residents in Turkey with a questionnaire
    B. Kaya, B. Karamustafaoglu Balci, K. Daglar, M. Polat, A. Tuten, H. Sahin, A. Soliman, O. Guralp
    Clinical and Experimental Obstetrics and Gynecology, 2017
  • The Bakri balloon implementation during cesarean section without switching to the lithotomy position
    Baris Kaya, Abdullah Tuten, Onur Guralp
    Case Reports in Perinatal Medicine, 2016
  • Which uterine sparing technique should be used for uterine atony during cesarean section? The Bakri balloon or the B-Lynch suture?
    Baris Kaya, Onur Guralp, Abdullah Tuten, Orhan Unal, Melih Ozgur Celik, Askın Dogan
    Archives of Gynecology and Obstetrics, 2016
  • Extra-abdominal removal of placenta during cesarean section: A prospective randomized controlled trial of a novel technique
    Baris Kaya, Onur Guralp, Korkut Daglar, Abdullah Tuten, Aygul Demirol, Eyup Yayci, Tijen Atacag, Askin Dogan
    Journal of Perinatal Medicine, 2016
  • Reply to: Bakri balloon vs. B-Lynch suture as hemostatic procedures for atonic bleeding: clarifications and concerns
    Baris Kaya
    Archives of Gynecology and Obstetrics, 2016
  • LOX-1 gene variants and maternal levels of plasma oxidized LDL and malondialdehyde in patients with gestational diabetes mellitus
    Birsen Aydemir, Onur Baykara, Fatma Behice Serinkan Cinemre, Hakan Cinemre, Abdullah Tuten, Ali Riza Kiziler, Nermin Akdemir, Mahmut Oncul, Baris Kaya, Volkan Sozer, Unal Erkorkmaz, Hafize Uzun
    Archives of Gynecology and Obstetrics, 2016
  • The value of complete blood count parameters in predicting preterm delivery
    European Review for Medical and Pharmacological Sciences, 2016
  • Proliferation of trophoblasts and Ki67 expression in preeclampsia
    Barış Kaya, Umit Nayki, Cenk Nayki, Pasa Ulug, Gokalp Oner, Emre Gultekin, Yusuf Yildirim
    Archives of Gynecology and Obstetrics, 2015
  • B-Lynch uterine compression sutures in the conservative surgical management of uterine atony
    Baris Kaya, Abdullah Tuten, Korkut Daglar, Murat Onkun, Seyhun Sucu, Askin Dogan, Orhan Unal, Onur Guralp
    Archives of Gynecology and Obstetrics, 2015
  • Balloon tamponade for the management of postpartum uterine hemorrhage
    Bariş Kaya, Abdullah Tuten, Korkut Daglar, Mesut Misirlioglu, Mesut Polat, Yusuf Yildirim, Orhan Unal, Gokhan Sami Kilic, Onur Guralp
    Journal of Perinatal Medicine, 2014
  • Response to: an easy insertion procedure of Bakri balloon during cesarean section for placenta previa: use of Nelaton rubber catheter
    Baris Kaya
    Archives of Gynecology and Obstetrics, 2014
  • Evaluation of ovarian reserve in Hashimoto's thyroiditis
    Abdullah Tuten, Esra Hatipoglu, Mahmut Oncul, Metehan Imamoglu, Abdullah Serdar Acikgoz, Nevin Yilmaz, Mustafa Dogan Ozcil, Baris Kaya, Ali Mesut Misirlioglu, Sezai Sahmay
    Gynecological Endocrinology, 2014
  • Non-invasive management of acute recurrent puerperal uterine inversion with Bakri postpartum balloon
    Barış Kaya, Abdullah Tüten, Havva Çelik, Mesut Mısırlıoğlu, Orhan Ünal
    Archives of Gynecology and Obstetrics, 2014
  • Copeptin is associated with the severity of endometriosis
    Abdullah Tuten, Mine Kucur, Metehan Imamoglu, Baris Kaya, Abdullah Serdar Acikgoz, Nevin Yilmaz, Zeynep Ozturk, Mahmut Oncul
    Archives of Gynecology and Obstetrics, 2014
  • Serum YKL-40 levels are altered in endometriosis
    Abdullah Tuten, Mine Kucur, Metehan Imamoglu, Mahmut Oncul, Abdullah Serdar Acikgoz, Nigar Sofiyeva, Zeynep Ozturk, Baris Kaya, Engin Oral
    Gynecological Endocrinology, 2014
  • Concurrent endometrial adenocarcinoma and an early pregnancy loss
    Aybala Akil, Baris Kaya, Ali Karabay, Yasemin Kibar
    Archives of Gynecology and Obstetrics, 2012
  • Gestational diabetes mellitus in patients receiving long-term corticosteroid therapy during pregnancy
    Yusuf Yildirim, Sivekar Tinar, Recai Soner Oner, Baris Kaya, Emrah Toz
    Journal of Perinatal Medicine, 2006
  • The use of complementary and alternative medicine (CAM) therapies by Turkish women with gynecological cancer
    European Journal of Gynaecological Oncology, 2006