Ana Claudia de Macedo Vieira

@farmacia.ufrj.br

DPNA/Laboratório de Farmacobotânica
Universidade Federal do Rio de Janeiro/Faculdade de Farmácia

Ana Claudia de Macedo Vieira

RESEARCH, TEACHING, or OTHER INTERESTS

Plant Science, Pharmaceutical Science, Ecology, Evolution, Behavior and Systematics, Education
26

Scopus Publications

Scopus Publications

  • Digital Humanities-Based Games: A Novel Approach for Mitigating Plant Awareness Disparity
    Mariana Aparecida de Almeida Souza, Ana Cláudia de Macêdo Vieira, Thiago Eliezer Siqueira, Gabriel Lima Prisco Madureira, Pedro Vieira Cruz, Ana Paula Ribeiro de Carvalho Ferreira, Tatiana Ungaretti Paleo Konno, Sérgio Manuel Serra da Cruz
    Digital Humanities Looking at the World Exploring Innovative Approaches and Contributions to Society, 2024
  • Pharmaceutical Evaluation of Medical Cannabis Extracts Prepared by Artisanal and Laboratory Techniques
    Virgínia Martins Carvalho, Juliana dos Santos Carmo, Lisia Maria Gobbo dos Santos, Fernando Gomes de Almeida, Ernesto Díaz Rocha, Ana Cláudia de Macêdo Vieira, Joana Angélica Barbosa Ferreira, Silvana do Couto Jacob, Robert M. Strongin, Antonio Jorge Ribeiro da Silva
    Revista Brasileira De Farmacognosia, 2023
  • Chemical profiling of Cannabis varieties cultivated for medical purposes in southeastern Brazil
    Virgínia Martins Carvalho, Fernando Gomes de Almeida, Ana Cláudia de Macêdo Vieira, Ernesto Díaz Rocha, Lucio Mendes Cabral, Robert M. Strongin
    Forensic Science International, 2022
  • Structure of leaf galls in clusia fluminensis planch and triana (Clusiaceae): Sex-biased development in a dioecious host plant
    André Guimarães, Ricardo Vieira, Ana Vieira
    Plants, 2021
    Galls are remarkable parasite–plant interactions that develop in different organs. They are induced by various organisms which manipulate or reprogram plant development. Galls in dioecious species and their effects on the host plant are seldom described in the literature. This paper presents a novel study of galls in a dioecious plant of the neotropical region. Our study aimed to analyze gall development and describe morphological and metabolic changes in galled leaves caused by Cecidomyiidae (Diptera) in Clusia fluminensis (Clusiaceae), a dioecious plant from Brazilian restinga. We investigated male and female individuals to detect different responses and sex-biased interactions. The non-galled leaves of female and male individuals of C. fluminensis exhibited similar anatomical structures. Nevertheless, galls developed only in male individuals. The activity of the Cecidomyiidae led to several morphological and anatomical changes, such as the hypertrophy of the leaf blade, especially the chlorenchyma. Our results indicated an interesting exception for the pattern of storage of lipids and starch in Cecidomyiidae galls, and sex-biased development in a dioecious plant, with the variation of metabolic compounds, especially phenolics and flavonoids, which may inhibit gall development in female individuals.
  • Qualitative terpene profiling of Cannabis varieties cultivated for medical purposes
    Ernesto Diaz Rocha, Vitória EA Silva, Fernanda CS Pereira, Valery M Jean, Fabio L Costa Souza, Leopoldo Clemente Baratto, Ana CM Vieira, Virgínia Martins Carvalho
    Rodriguesia, 2020
    With the upcoming medical Cannabis regulation, quality control methods on raw material will be required. Besides testing for contaminants and potency, there are also pharmaceutical and forensic interests in the determination of the terpene profile in different strains of Cannabis as complementary identification methods. A simple non-destructive HS-SPME GC-MS method was used to identify the terpene content in twelve Cannabis samples, four of them were of the hemp type (Harle-tsu), seven from various marihuana types and one of the intermediate type. They all were previously analyzed by HPLC to determine the potency (THC and CBD content). Spectral library matching was used to identify the terpenes compounds. Thirty terpenes compounds were detected, nine of them were present in all Cannabis samples and used to find their terpene profile: α-pinene, β-pinene, β-myrcene, D-limonene, terpinolene, linalool, caryophyllene, α-bergamotene and humulene. Three of them, caryophyllene, α-pinene and β-myrcene were found as larger components in most of samples. A principal components analyses (PCA) was performed. The four hemp type samples showed two different profiles, two samples showed caryophyllene as main component and the others two with β-myrcene as such. The marihuana type samples showed wider profiles with no clear patterns at all, which is not surprising because of the low number of samples. The simple methodology shows viable to set the terpenes profile for analyses of raw Cannabis material. Suitability for differentiation between different sorts of types needs more studies, with increasing numbers of samples.
  • Heating, identification, and determination of pesticides residues in black bean samples
    Joyce A.T. Miranda, Lucia M.J. Carvalho, Izabela M. Castro, Marianna R. Anjos, Jose Luiz Carvalho, et al.
    Chemical Engineering Transactions, 2020
    The advantages associated with pesticide application in increasing agricultural productivity must be weighed against the possible danger to health and the environment. Above all, the application of these agents must be in accordance with good agricultural practice. The presence of pesticide residues above acceptable daily intake values and maximum residue limits is of concern from a food safety point of view. The removal of food residues by processing may be affected by the nature of the food, type of active ingredient and specificity of the processing applied. Chronic organophosphate contamination can affect the renal, reproductive, respiratory and nervous systems. The present work aimed to identify and determine the residues of ten organophosphates (chlorpyrifos, etione, malathion, methamidophos, parathion-methyl, phenthoate, phorate, pirimiphos-methyl, terbuphos, pyrazophos, and triazophos) added to common bean samples (Phaseolus vulgaris) and to observe the effect of heat treatment on these analytes. The QuEChERS method (Quick, Easy, Cheap, Effective, Robust and Safe) was used for the extraction of multiple waste before and after heating. Gas chromatography coupled to the thermionic flame detector (FTD) was used to identify and determine the analytes. Moreover, in this study, the methodology was also validated by determining the ten organophosphates previously mentioned, and metamidophos by studies of selectivity, linearity, intermediate precision, detection limit, quantification limit and precision study by addition and recovery. According to the results obtained in the work, it was possible to notice that, under the conditions in which the experiments were conducted, the organophosphates were thermosensitive. The temperature and cooking time used were lower than traditional beans dishes. The method was selective for all analytes, as there was no interference greater than 30% of the quantification limit. The limits of detection were between 1.60 and 52.96 ng.kg-1 and the limits of quantification were between 3.30 and 176.0 ng.kg-1. Regarding intermediate precision, the differences in area values were = 15 % at different concentrations except for phorate. The correlation coefficients (r) of the linearity curves were greater than 0.99 for all active ingredients within the applied working range. The recovery percentage was between 70 and 120 %, except phorate. Thus, the methodology was satisfactory for the identification and determination of nine of the eleven organophosphates analyzed in beans.
  • Scanning electron microscopy and crystallinity of starches granules from cowpea, black and carioca beans in raw and cooked forms
    Joyce Aparecida Tavares de MIRANDA, Lucia Maria Jaeger de CARVALHO, Ana Claudia de Macedo VIEIRA, Izabela Miranda de CASTRO
    Food Science and Technology Brazil, 2019
    Beans are a vital food for the population around the world because it contains a relatively high amount of protein, vitamins, fiber, and minerals, being an important vegetable source of iron, particularly when combined with ascorbic acid and cysteine. The starch content in the seed is between 45 and 60%. This paper evaluated the granular structure of starches from common beans (Phaseolus vulgaris) and cowpea (Vigna unguiculata) in raw and cooked forms by Scanning Electron Microscopy (SEM), and their crystallinity by X-ray diffraction (DR-X). By SEM, was observed the occurrence of gelatinization phenomenon in cowpea and carioca beans, and the resistance to this event in black beans. By DR-X, the diffraction angles found in this work are more consistent with the classification of the standard polyphorm A. The Relative Crystallinity (RC) of black bean cowpea and carioca beans, observed by X-ray diffraction, varied significantly.
  • Influence of heating on residues of organophosphates added to cowpea samples
    Joyce Miranda, Lucía María Jaeger de Carvalho, I. M. de Castro, Marianna Ramos dos Anjos, Veronica Figueiredo, et al.
    Chemical Engineering Transactions, 2019
    The inappropriate use of pesticides can have a great impact on the environment and ecosystems. In human health, chronic organophosphate contamination can affect the renal, reproductive, respiratory and nervous systems. The presence of these active ingredients is more worrying considering the cumulative effect, which would be the sum of how much is consumed at each meal, and the contamination of soil, aquifers and groundwater. Mainly concern is the wide exposure subjected by rural workers and their families. The present work had as objective to identify and determine residues of ten organophosphates added to cowpea samples (Vigna unguiculata), and to observe the effect of the thermal treatment in these analytes. The QuEChERS method (Quick, Easy, Cheap, Effective, Rugged, and Safe) was used to the multiresidues extraction before and after heating. Gas chromatography coupled to the thermionic flame detector (FTD) was used in the identification and determination of the analytes. According to the results obtained in the work, it was possible to perceive that under the conditions in which the experiments were conducted, the organophosphates showed to be thermosensitive. Temperature and time of cooking used were under to the ones routinely used in the domestic kitchens for the preparation of beans. Keywords: organophosphates; QuEChERS; thermosens
  • Anatomical Traits of Pumpkin (Cucurbita moschata Duch) as Evaluation Parameters of Bioaccessibility of Carotenoids
    André Luis de Alcantara Guimarães, Lucía María Jaeger de Carvalho, Ana Rita Vieira, Joyce Miranda, Fernanda Dias Abadio Finco, et al.
    Chemical Engineering Transactions, 2019
    Pumpkin (Cucurbita moschata Duch.) has high potential as source of carotenoids with provitamin A activity, especially all-trans-ß-carotene, and are widely consumed by the Brazilian population. Consumption may be useful in preventing the vitamin A deficiency, which corresponds to a public health concern in Brazil. The cooking style can affect the carotenoids retention, induce the isomerization cis-trans of the ß-carotene, bioaccessibility and bioavailability. The aim of this study was to evaluate the bioaccessibility of carotenoids in biofortified pumpkins submitted to different cooking styles through microscopic techniques. Five biofortified pumpkin genotypes were submitted to three cooking methods (boiled in water, steam and microwave oven). The anatomical analyses revealed some differences regarding the integrity and morphological traits of parenchyma cells from mesocarp, related to the type and time of cooking. In natura samples revealed intact fragments with round shaped cells connected to each other, the middle lamella preservation and, carotenoids preserved in the plastids. The cooking preparation with boiling water harmed most of middle lamella, resulting in small fragments and abundant isolated mesocarp parenchyma cells. These cells had variable shapes, round but most exhibiting flatten and collapsed cells, but still intact with preserved cell walls. Broken cells were rare. Carotenoids were abundant within the cells. The microwave oven cooking showed that mesocarp parenchyma cells remain mostly preserved, with most cells still connected to each other, which indicates the integrity of middle lamella. The cells showed rounded shape, and carotenoids were abundant and preserved within cells. Preparations with water vapor for 5 minutes exhibited sparse isolated cells and small fragments with cells still connected to each other. Most isolated cells showed rounded and flattened shapes, mostly collapsed but still preserved cell walls. Carotenoids were abundantly preserved within mesocarp parenchyma cells. Those cells which retained the integrity of middle lamella were still bonded to each other. They remained mostly rounded shaped, and carotenoids were within cells. Thus, cell walls and chromoplasts act as barriers that retain carotenoids encapsulated avoiding their cell release and absorption during digestion, compromising their bioaccessibility. Keywords: carotenoids; pumpkin; bioavailability; bioaccessib
  • Vision paper: Challenges and opportunities of social computing in urban agriculture in global north and south countries
    Ceur Workshop Proceedings, 2018
  • Comparative anatomy and chemical analysis of the vegetative organs of three species of Stigmaphyllon (Malpighiaceae)
    André Luis de Alcantara Guimarães, Renato Pamplona Cardoso Costa, Lucio Mendes Cabral, Ana Cláudia de Macêdo Vieira
    Flora Morphology Distribution Functional Ecology of Plants, 2016
  • Structure and development of 'witches' broom' galls in reproductive organs of Byrsonima sericea (Malpighiaceae) and their effects on host plants
    A. L. A. Guimarães, P. M. Neufeld, L. D. R. Santiago‐Fernandes, A. C. M. Vieira
    Plant Biology, 2015
  • Technological Management of Small Crops Through Mobile Apps and Precision Agriculture
    Sbsi 2015 Proceedings of the Annual Conference on Brazilian Symposium on Information Systems Information Systems A Computer Socio Technical Perspective, 2015
  • Structure of floral galls of Byrsonima sericea (Malpighiaceae) induced by Bruggmanniella byrsonimae (Cecidomyiidae, Diptera) and their effects on host plants
    A. L. A. Guimarães, S. M. S. Cruz, A. C. M. Vieira
    Plant Biology, 2014
  • Quality assessment of samples of medicinal plants marketed in Brazil
    Revista De Ciencias Farmaceuticas Basica E Aplicada, 2014
  • Characterisation of the effects of leaf galls of Clusiamyia nitida (Cecidomyiidae) on Clusia lanceolata Cambess. (Clusiaceae): Anatomical aspects and chemical analysis of essential oil
    André Luis de Alcantara Guimarães, Carlos Henrique Brasil Bizarri, Leandro Silva Barbosa, Marcos Jun Nakamura, Mônica Freiman de Souza Ramos, Ana Cláudia de Macêdo Vieira
    Flora Morphology Distribution Functional Ecology of Plants, 2013
  • Leaf anatomy and its contribution to the systematics of Aechmea subgenus Macrochordion (de Vriese) Baker (Bromeliaceae)
    Ana Paula G. de Faria, Ana Claudia M. Vieira, Tânia Wendt
    Anais Da Academia Brasileira De Ciencias, 2012
  • The natural impact of banana inflorescences (Musa acuminata) on human nutrition
    Catharina E. Fingolo, João M.A. Braga, Ana C.M. Vieira, Mirian R.L. Moura, Maria Auxiliadora C. Kaplan
    Anais Da Academia Brasileira De Ciencias, 2012
  • Towards provenance metadata on chemical-inspired workflow engines
    International Conference on Information Society I Society 2012, 2012
  • Managing semantic annotations on medicinal plants
    Sergio Manuel Serra da Cruz, Ana Claudia de Macedo Vieira
    2010 International Conference on Information Society I Society 2010, 2010
  • Comparative study on nutritional and morphological aspects of lychees (Litchi chinensis Sonn.) after osmotic pre-treatment and conventional dehydration
    5th International Technical Symposium on Food Processing Monitoring Technology in Bioprocesses and Food Quality Management, 2009
  • SEMANTIC annotations and retrieval of pharmacobtanical data
    Csedu 2009 Proceedings of the 1st International Conference on Computer Supported Education, 2009
  • Microscopic quality indicators of minas frescal cheese
    Tais B. de Souza, Adriano G. da Cruz, Mirian R.L. Moura, Ana Cláudia de M. Vieira, Anderson de S. Sant’Ana
    Food Control, 2008
  • Pharmacognostic study of sumare - Cyrtopodium paranaense Schltr (Orchidaceae)
    Revista Brasileira De Farmacia, 2000
  • Edematogenic activity in Philodendron corcovadense Kunth
    Revista Brasileira De Farmacia, 1999
  • Pharmacognostic study of capim rei: Anatomical aproach
    Revista Brasileira De Farmacia, 1998