Ana Sofia Tomaz Teixeira de Padua

@cenimat.fct.unl.pt

CENIMAT|i3N, Department of Materials Science, School of Science and Technology, Nova University Lisbon
CENIMAT|i3N

Ana Sofia Tomaz Teixeira de Padua


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https://researchid.co/a.sofiapdua

EDUCATION

PhD in Materials Science and Engineering, Feb2021 — Sep2025 at School of Science and Technology, Nova University Lisbon, 2829-516
Integrated master in Micro and Nanotechnologies Engineering, Sept2014 — Nov2019 at School of Science and Technology, Nova University Lisbon, 2829-516

RESEARCH, TEACHING, or OTHER INTERESTS

Materials Science, Biomaterials, Biomedical Engineering, Ceramics and Composites
18

Scopus Publications

336

Scholar Citations

10

Scholar h-index

10

Scholar i10-index

Scopus Publications

  • Multifunctional therapeutic ion-doped bioactive glasses for enhanced bone regeneration, immunomodulation, and antibacterial applications
    A. Sofia Pádua, João Paulo Borges, Manuel Pedro Fernandes Graça, Jorge Carvalho Silva
    Materials Today, 2026
    One of the major challenges of tissue engineering is developing biomaterials that simultaneously promote tissue regeneration and prevent bacterial infections. Bioactive glasses (BGs) have a well-established reputation for inducing angiogenesis and osteogenesis in hard-tissue applications but often exhibit insufficient antibacterial efficacy to prevent biofilm formation under clinically relevant conditions. The incorporation of various therapeutic inorganic ions into BGs has emerged as a promising strategy to overcome this limitation and enhance biological responses, including osteogenesis, angiogenesis, immunomodulation, antioxidant activity, and antimicrobial properties. This review systematically categorizes dopants based on their chemical nature, highlighting their specific biological and antimicrobial effects. For each ion, the proposed mechanisms by which they promote bone regeneration, angiogenesis, immunomodulation, and antibacterial activity are discussed. Additionally, the review addresses advanced applications of doped and co-doping BGs in theragnostic and theragenerative therapies, including selective cytotoxicity toward cancer cells, bio-labelling imaging capabilities, photothermal properties, and hemostatic functions. By integrating current findings on doped BG compositions, surface morphologies, and their interactions with immune and bone cells, this review provides a detailed framework for designing next-generation multifunctional BG-based biomaterials. These materials hold significant potential to overcome existing limitations in antibacterial capacity and mechanical properties, thereby advancing clinical outcomes in bone tissue engineering and implantology.
  • Electrospun membranes from natural polymers with Quercetin: design and characterization, antioxidant and antimicrobial activity, and potential for skin reinnervation in chronic wounds
    Catarina Correia, Ana Sofia Pádua, Catarina Matela, Inês C. Gonçalves, Paula Soares, Célia Henriques, Isabel Sá-Nogueira, Jorge Carvalho Silva, Tânia Vieira
    International Journal of Pharmaceutics, 2025
    • Citric acid was effective in crosslinking chitosan/gelatin electrospun membranes. • Quercetin had a higher release percentage at basic pH (wound site condition). • Quercetin-loaded electrospun membranes had antioxidant and antimicrobial activity. • Quercetin induced the neuronal differentiation of SH-SY5Y cell line. The rising problem of chronic wounds demands the investigation of therapeutic solutions that are easy to use, target microbial infection and excessive reactive oxygen species (ROS) at the wound site, and account for skin reinnervation. The aim of this research was to develop electrospun membranes from natural polymers – chitosan (CS) and fish gelatin (FG) − crosslinked with citric acid, incorporating quercetin as an active pharmaceutical ingredient (API) to enhance its therapeutic potential. The produced membranes exhibited a uniform morphology and a cross-shaped network, providing porosity and the ability to sustain hydrolytic degradation. Drug delivery assays revealed a higher release percentage at pH 7.4 and pH 8, which correspond to wound site conditions. However, quercetin degradation at this pH suggests the need for encapsulation. Antioxidant activity analysis confirmed quercetin’s great antioxidant capabilities, reaching up to 93.71 ± 0.92 % for pure quercetin, and 53.77 ± 3.09 % for quercetin-containing fibers. Neuronal differentiation assays demonstrated quercetin’s ability to promote neuronal differentiation. Antibacterial activity was tested for the membranes against Escherichia coli ( E. coli ) and Methycillin-resistant staphylococcus aureus (MRSA). The results showed a beneficial effect from incorporating quercetin into the membranes in reducing MRSA growth but no noticeable effects on E. coli . These findings highlight the potential of quercetin-loaded fibers for wound healing applications, with antioxidant, antibacterial, and neurogenic properties.
  • Developing thermoresponsive p(NIPAAm-HMAAm) electrospun nanofibers for on-demand drug release of doxorubicin
    Adriana Gonçalves, Susete N. Fernandes, A. Sofia Pádua, Jorge Carvalho Silva, João Paulo Borges, Miguel Castilho, Paula I.P. Soares
    Journal of Drug Delivery Science and Technology, 2025
  • Polycaprolactone/Doped Bioactive Glass Composite Scaffolds for Bone Regeneration
    Ana Sofia Pádua, Manuel Pedro Fernandes Graça, Jorge Carvalho Silva
    Journal of Functional Biomaterials, 2025
    Critical-size bone defects do not heal spontaneously and require external support, making bone regeneration a central challenge in tissue engineering. Polymeric/ceramic composite scaffolds offer a promising approach to mimic the structural and biological properties of bone. In this study, we aimed to evaluate the effect of different doping oxides in bioactive glass (BG) on the performance of polycaprolactone (PCL)-based composite scaffolds for bone tissue engineering applications. Composite scaffolds were fabricated using solvent casting, hot pressing, and salt-leaching techniques, combining PCL with 25 wt% of BG or doped BG containing 4 mol% of tantalum, zinc, magnesium, or niobium oxides, and 1 mol% of copper oxide. The scaffolds were characterized in terms of morphology, mechanical properties, and in vitro biological performance. All scaffolds exhibited a highly porous, interconnected structure. Mechanical compression tests indicated that elastic modulus increased with ceramic content, while doping had no measurable effect. Cytotoxicity assays confirmed biocompatibility across all scaffolds. Among the tested materials, the Zn-doped BG/PCL scaffold uniquely supported cell adhesion and proliferation and significantly enhanced alkaline phosphatase (ALP) activity—an early marker of osteogenic differentiation—alongside the Nb-doped scaffold. These results highlight the Zn-doped BG/PCL composite as a promising candidate for bone regeneration applications.
  • Influence of zirconium dioxide (ZrO2) and magnetite (Fe3O4) additions on the structural, electrical, and biological properties of Bioglass® for metal implant coatings
    Imen Hammami, Manuel Pedro Fernandes Graça, Sílvia Rodrigues Gavinho, Joana Soares Regadas, Suresh Kumar Jakka, Ana Sofia Pádua, Jorge Carvalho Silva, Isabel Sá-Nogueira, João Paulo Borges
    Frontiers in Bioengineering and Biotechnology, 2025
    BackgroundThe growing need for durable implants, driven by aging populations and increased trauma cases, highlights challenges such as limited osseointegration and biofilm formation. 45S5 Bioglass® has shown promise due to its bioactivity, antimicrobial properties, and ability to enhance osseointegration through electrical polarization. This study investigates the effects of incorporating different concentrations of ZrO2 and Fe3O4 into 45S5 Bioglass® to enhance its electrical and biological properties.MethodsRaman analysis was used to evaluate how these oxides influenced the amount of non-bridging oxygens (NBOs) and glass network connectivity. Electrical characterization was performed using impedance spectroscopy to measure conductivity and ion mobility. Antibacterial activity was assessed using the agar diffusion method, and bioactivity was evaluated through simulated body fluid (SBF) immersion tests.ResultsThe results revealed that bioglasses containing ZrO2 exhibited higher NBO content compared to Fe3O4, leading to improved electrical and biological properties. ZrO2, particularly at 2 mol%, significantly enhanced conductivity, antibacterial activity, and bioactivity. In contrast, Fe3O4 reduced both antibacterial activity and bioactivity.ConclusionThe findings demonstrate that ZrO2 addition improves the electrical and biological performance of 45S5 Bioglass®, making it a promising candidate for durable implants. Fe3O4, however, showed limited benefits.
  • Green Sol–Gel Synthesis of Iron Oxide Nanoparticles for Magnetic Hyperthermia Applications
    Juliana Jesus, Joana Regadas, Bárbara Costa, João Carvalho, Ana Pádua, Célia Henriques, Paula I. P. Soares, Sílvia Gavinho, Manuel A. Valente, Manuel P. F. Graça, Sílvia Soreto Teixeira
    Pharmaceutics, 2024
    Background/Objectives: The unique properties of iron oxide nanoparticles have attracted significant interest within the biomedical community, particularly for magnetic hyperthermia applications. Various synthesis methods have been developed to optimize these nanoparticles. Methods: In this study, we employed a powdered coconut water (PCW)-assisted sol–gel method to produce magnetite nanoparticles for the first time. A comprehensive analysis of the thermal (differential thermal analysis and thermogravimetry), structural (X-ray diffraction), morphological (scanning electron microscopy with energy dispersive spectroscopy), magnetic (vibrating sample magnetometer and hyperthermia), and biological (cytotoxicity essays) properties was conducted to assess their potential for magnetic hyperthermia. Results: Samples heat-treated at 700 °C and 400 °C (washed powder) for 4 h under argon presented only magnetite in their composition. The micrometer-sized particles exhibited ferrimagnetic behavior, with saturation magnetization values of 37, 76, and 10 emu/g and specific absorption rates (SAR) of 27.1, 19.9, and 14.1 W/g, respectively, for treatments at 350 °C (48 h), 700 °C (4 h), and 400 °C (washed powder, 4 h) under an argon atmosphere. Biological tests showed no cytotoxicity below 10 mg/mL. Conclusions: The findings highlight the potential of PCW-assisted synthesis as a sustainable and efficient strategy for producing pure magnetite, with powder washing preceding the heat treatment enabling the attainment of this phase at lower temperatures. Nevertheless, the micrometer-scale dimensions is observed in the morphological analysis limit their suitability for biomedical applications.
  • Electrospun poly(N-vinylpyrrolidone) membranes with Ag nanoparticles for wound dressings: Production and characterization
    Ana Sofia Pádua, Rita Morais Rosa, Tânia Vieira, Célia Henriques, Jorge Carvalho Silva
    Journal of Drug Delivery Science and Technology, 2024
    Wound dressings have long been used to promote the healing of skin injuries. In the work reported here, fibrous membranes were produced by electrospinning poly(N-vinylpyrrolidone) (PVP) solutions containing silver nitrate at varying mass ratios (1:200, 1:100 and 1:50 AgNO 3 :PVP). PVP solutions without AgNO 3 were used as a control. The electrospun membranes were irradiated using 254 nm UV light to simultaneously photo-crosslink PVP and promote the formation of silver nanoparticles (AgNPs). The formation of AgNPs was confirmed by scanning electron microscopy and transmission electron microscopy, as well as by detecting the surface plasmon resonance peak at 420 nm in the UV–Vis spectrum during release studies. The swelling rate of fibrous membranes was lower for those containing AgNPs compared to PVP-only membranes. The Kirby-Bauer diffusion test performed against Escherichia coli , Pseudomonas aeruginosa , Staphylococcus aureus , Staphylococcus epidermidis and Candida albicans showed that all AgNPs-containing membranes exhibited an inhibitory effect on all microorganisms tested. The in vitro cytotoxicity assay showed that membranes with lower silver concentration were less cytotoxic. This study presents a simple route to producing a wound dressing with antimicrobial action that has a swelling behavior capable of absorbing exudates, provides controlled release of silver and has low cytotoxicity. A PVP/AgNPs nanofibrous wound dressing with antimicrobial activity and low cytotoxicity. • A wound dressing based on polyvinylpyrrolidone and silver nanoparticles. • Green method used to produce the nanoparticles and crosslink PVP. • Antimicrobial (Gram-positive and Gram-negative) and antifungal activity. • Low cytotoxicity for the dressing containing an AgNO 3 /PVP mass ratio of 1:200.
  • In Vitro Characterization of Doped Bioglass 45S5/HAp Coatings Obtained by CoBlastTM Deposition
    Ana Sofia Pádua, Sílvia Rodrigues Gavinho, Tânia Vieira, Imen Hammami, Jorge Carvalho Silva, João Paulo Borges, Manuel Pedro Fernandes Graça
    Coatings, 2023
    Bone replacement is one of the major medical procedures in the oral surgery field due to the progressive ageing population and to illness or trauma in younger age groups. The use of implants without biological activity and effective osseointegration increases the chances of implant failure. This work aims to improve the interaction between implants and bone by using Bioglass 45S5 (BG)/hydroxyapatite (HAp) mixtures, including copper-, zinc-, and cerium-doped BG, as well as co-doping by the mentioned metals, as coatings produced by the CoBlastTM technique. All coatings present a uniform coverage of the Ti-6Al-4V substrate. Furthermore, in vitro testing using human osteosarcoma Saos-2 cells indicated that BG/HAp coatings have no cytotoxic effect, and the used of doping agents did not alter cell adhesion, proliferation, or alkaline phosphatase (ALP) expression when compared to undoped coating. These results demonstrate that BG/HAp by CoBlastTM can be a solution to improve implants’ osseointegration.
  • Bioactive Glasses Containing Strontium or Magnesium Ions to Enhance the Biological Response in Bone Regeneration
    Sílvia Rodrigues Gavinho, Ana Sofia Pádua, Laura Isabel Vilas Holz, Isabel Sá-Nogueira, Jorge Carvalho Silva, João Paulo Borges, Manuel Almeida Valente, Manuel Pedro Fernandes Graça
    Nanomaterials, 2023
    The non-surgical treatments are being required to reconstruct damaged tissue, prioritizing our body’s natural healing process. Thus, the use of bioactive materials such as bioactive glass has been studied to support the repair and restoration of hard and soft tissue. Thus, in this work Bioglass 45S5 was developed, adding 1 and 2%mol of SrO or MgO and the physical and biological properties were evaluated. The addition of MgO and SrO at the studied concentrations promoted the slight increase in non-bridging oxygens number, observed through the temperature shift in phase transitions to lower values compared to Bioglass 45S5. The insertion of the ions also showed a positive effect on Saos-2 cell viability, decreasing the cytotoxic of Bioglass 45S5. Besides the Ca/P ratio on the pellets surface demonstrating no evidence of higher reactivity between Bioglass 45S5 and Bioglass with Sr and Mg, micrographs show that at 24 h the Ca/P rich layer is denser than in Bioglass 45S5 after the contact with simulated body fluid. The samples with Sr and Mg show a higher antibacterial effect compared to Bioglass 45S5. The addition of the studied ions may benefit the biological response of Bioglass 45S5 in dental applications as scaffolds or coatings.
  • Influence of the Particle Size on the Electrical, Magnetic and Biological Properties of the Bioglass® Containing Iron Oxide
    Joana Soares Regadas, Sílvia Rodrigues Gavinho, Sílvia Soreto Teixeira, Juliana Vieira de Jesus, Ana Sofia Pádua, Jorge Carvalho Silva, Susana Devesa, Manuel Pedro Fernandes Graça
    Magnetochemistry, 2023
    Bioglasses have been used throughout the past century as a biomaterial in the bone regeneration field. However, recent studies have attempted to use them as a therapeutic material as well, mainly in the treatment of osteosarcomas. The most widely recognized bioglass is the 45S5 Bioglass, invented by Larry Hench et al., which presents higher bioactivity. A possible application of this bioglass in the treatment of osteosarcomas can be accomplished by adding specific ions, such as iron, that will allow the use of magnetic hyperthermia and Fenton reaction as therapeutic mechanisms. In this study, a 45S5 Bioglass containing 10%mol of Fe2O3 was produced using the melt-quenching method. A group of samples was prepared by changing the overall ball milling time, from 1 h up to 48 h, to analyze the effects of iron in the bioactive glass matrix and evaluate the influence of particle size on their physical and biological properties. The studied bioglasses showed no evidence of changes in the amorphous structural nature compared to the 45S5 Bioglass. The data of the impedance spectroscopy study revealed that the addition of Fe2O3 can increase the standard rate constant of the Electro-Fenton reaction, with the sample milled for 12 h showing the most promising results. The reduction in the particle size influenced the cytotoxicity and the bioactivity. The samples with lower particle sizes showed a higher level of cytotoxicity.
  • Bioactive Glass Modified with Zirconium Incorporation for Dental Implant Applications: Fabrication, Structural, Electrical, and Biological Analysis
    Imen Hammami, Sílvia Rodrigues Gavinho, Ana Sofia Pádua, Isabel Sá-Nogueira, Jorge Carvalho Silva, João Paulo Borges, Manuel Almeida Valente, Manuel Pedro Fernandes Graça
    International Journal of Molecular Sciences, 2023
  • Antibacterial Biomaterial Based on Bioglass Modified with Copper for Implants Coating
    Imen Hammami, Sílvia Rodrigues Gavinho, Suresh Kumar Jakka, Manuel Almeida Valente, Manuel Pedro Fernandes Graça, Ana Sofia Pádua, Jorge Carvalho Silva, Isabel Sá-Nogueira, João Paulo Borges
    Journal of Functional Biomaterials, 2023
  • Chitosan scaffolds with mesoporous hydroxyapatite and mesoporous bioactive glass
    Ana Sofia Pádua, Lígia Figueiredo, Jorge Carvalho Silva, João Paulo Borges
    Progress in Biomaterials, 2023
  • Hydroxyapatite-Barium Titanate Biocoatings Using Room Temperature Coblasting
    Inês J. G. Dias, A. Sofia Pádua, Eduardo A. Pires, João P. M. R. Borges, Jorge C. Silva, M. Carmo Lança
    Crystals, 2023
  • Extensive Investigation on the Effect of Niobium Insertion on the Physical and Biological Properties of 45S5 Bioactive Glass for Dental Implant
    Imen Hammami, Sílvia Rodrigues Gavinho, Ana Sofia Pádua, Maria do Carmo Lança, João Paulo Borges, Jorge Carvalho Silva, Isabel Sá-Nogueira, Suresh Kumar Jakka, Manuel Pedro Fernandes Graça
    International Journal of Molecular Sciences, 2023
  • Fabrication, Structural and Biological Characterization of Zinc-Containing Bioactive Glasses and Their Use in Membranes for Guided Bone Regeneration
    Sílvia R. Gavinho, Ana Sofia Pádua, Isabel Sá-Nogueira, Jorge C. Silva, João P. Borges, Luis C. Costa, Manuel Pedro F. Graça
    Materials, 2023
  • Biocompatibility, Bioactivity, and Antibacterial Behaviour of Cerium-Containing Bioglass®
    Sílvia R. Gavinho, Ana Sofia Pádua, Isabel Sá-Nogueira, Jorge C. Silva, João P. Borges, Luis C. Costa, Manuel Pedro F. Graça
    Nanomaterials, 2022
  • Synthesis and Characterization of Iron Containing Bioactive Glass for Implants
    I. Hammami, S.R. Gavinho, A.S. Padua, M. P. F. Graca, J.C. Silva
    2022 10th E Health and Bioengineering Conference Ehb 2022, 2022

RECENT SCHOLAR PUBLICATIONS

  • Electrospun membranes from natural polymers with Quercetin
    C Correia, AS Pádua, C Matela, IC Gonçalves, P Soares, C Henriques, ...
    2025
  • Developing thermoresponsive p (NIPAAm-HMAAm) electrospun nanofibers for on-demand drug release of doxorubicin
    A Gonçalves, SN Fernandes, AS Pádua, JC Silva, JP Borges, M Castilho, ...
    Journal of Drug Delivery Science and Technology 112, 107244 , 2025
    2025
    Citations: 4
  • Electrospun membranes from natural polymers with Quercetin: design and characterization, antioxidant and antimicrobial activity, and potential for skin reinnervation in chronic …
    C Correia, AS Pádua, C Matela, IC Gonçalves, P Soares, C Henriques, ...
    International Journal of Pharmaceutics, 126062 , 2025
    2025
    Citations: 3
  • Polycaprolactone/Doped Bioactive Glass Composite Scaffolds for Bone Regeneration
    AS Pádua, MPF Graça, JC Silva
    Journal of Functional Biomaterials 16 (6), 200 , 2025
    2025
    Citations: 7
  • Influence of zirconium dioxide (ZrO 2 ) and magnetite (Fe 3 O 4 ) additions on the structural, electrical, and biological properties of Bioglass ® for metal implant coatings
    I Hammami, MP Fernandes Graça, SR Gavinho, JS Regadas, SK Jakka, ...
    Frontiers in Bioengineering and Biotechnology 13, 1537856 , 2025
    2025
    Citations: 8
  • Green sol–gel synthesis of iron oxide nanoparticles for magnetic hyperthermia applications
    J Jesus, J Regadas, B Costa, J Carvalho, A Pádua, C Henriques, ...
    Pharmaceutics 16 (12), 1578 , 2024
    2024
    Citations: 18
  • Electrospun poly (N-vinylpyrrolidone) membranes with Ag nanoparticles for wound dressings: Production and characterization
    AS Pádua, RM Rosa, T Vieira, C Henriques, JC Silva
    Journal of Drug Delivery Science and Technology 101, 106303 , 2024
    2024
    Citations: 4
  • Electrospun poly (N-vinylpyrrolidone) membranes with Ag nanoparticles for wound dressings
    AS Pádua, RM Rosa, T Vieira, C Henriques, JC Silva
    2024
  • In Vitro Characterization of Doped Bioglass 45S5/HAp Coatings Obtained by CoBlast TM Deposition
    AS Pádua, SR Gavinho, T Vieira, I Hammami, JC Silva, JP Borges, ...
    Coatings 13 (10), 1775 , 2023
    2023
    Citations: 11
  • Bioactive glasses containing strontium or magnesium ions to enhance the biological response in bone regeneration
    SR Gavinho, AS Pádua, LIV Holz, I Sá-Nogueira, JC Silva, JP Borges, ...
    Nanomaterials 13 (19), 2717 , 2023
    2023
    Citations: 49
  • Influence of the Particle Size on the Electrical, Magnetic and Biological Properties of the Bioglass ® Containing Iron Oxide
    JS Regadas, SR Gavinho, SS Teixeira, JV de Jesus, AS Pádua, JC Silva, ...
    Magnetochemistry 9 (9), 209 , 2023
    2023
    Citations: 10
  • Antibacterial biomaterial based on bioglass modified with copper for implants coating
    I Hammami, SR Gavinho, SK Jakka, MA Valente, MPF Graça, AS Pádua, ...
    Journal of Functional Biomaterials 14 (7), 369 , 2023
    2023
    Citations: 27
  • Bioactive Glass Modified with Zirconium Incorporation for Dental Implant Applications
    I Hammami, SR Gavinho, AS Pádua, I Sá-Nogueira, JC Silva, JP Borges, ...
    2023
  • Bioactive Glass Modified with Zirconium Incorporation for Dental Implant Applications: Fabrication, Structural, Electrical, and Biological Analysis
    I Hammami, SR Gavinho, AS Pádua, I Sá-Nogueira, JC Silva, JP Borges, ...
    International Journal of Molecular Sciences 24 (13), 10571 , 2023
    2023
    Citations: 31
  • Chitosan scaffolds with mesoporous hydroxyapatite and mesoporous bioactive glass
    AS Pádua, L Figueiredo, JC Silva, JP Borges
    Progress in Biomaterials 12 (2), 137-153 , 2023
    2023
    Citations: 33
  • Hydroxyapatite-Barium Titanate Biocoatings Using Room Temperature Coblasting
    IJG Dias, AS Pádua, EA Pires, JPMR Borges, JC Silva, MC Lança
    Crystals 13 (4), 579 , 2023
    2023
    Citations: 5
  • Extensive investigation on the effect of niobium insertion on the physical and biological properties of 45S5 bioactive glass for dental implant
    I Hammami, SR Gavinho, AS Pádua, MC Lança, JP Borges, JC Silva, ...
    International Journal of Molecular Sciences 24 (6), 5244 , 2023
    2023
    Citations: 29
  • Fabrication, structural and biological characterization of zinc-containing bioactive glasses and their use in membranes for guided bone regeneration
    SR Gavinho, AS Pádua, I Sá-Nogueira, JC Silva, JP Borges, LC Costa, ...
    Materials 16 (3), 956 , 2023
    2023
    Citations: 36
  • Hydroxyapatite-Barium Titanate Biocoatings Using Room Temperature Coblasting. Crystals 2023, 13, 579
    IJG Dias, AS Pádua, EA Pires, J Borges, JC Silva, MC Lança
    2023
  • Biocompatibility, Bioactivity, and Antibacterial Behaviour of Cerium-Containing Bioglass ®
    SR Gavinho, AS Pádua, I Sá-Nogueira, JC Silva, JP Borges, LC Costa, ...
    Nanomaterials 12 (24), 4479 , 2022
    2022
    Citations: 49

MOST CITED SCHOLAR PUBLICATIONS

  • Bioactive glasses containing strontium or magnesium ions to enhance the biological response in bone regeneration
    SR Gavinho, AS Pádua, LIV Holz, I Sá-Nogueira, JC Silva, JP Borges, ...
    Nanomaterials 13 (19), 2717 , 2023
    2023
    Citations: 49
  • Biocompatibility, Bioactivity, and Antibacterial Behaviour of Cerium-Containing Bioglass ®
    SR Gavinho, AS Pádua, I Sá-Nogueira, JC Silva, JP Borges, LC Costa, ...
    Nanomaterials 12 (24), 4479 , 2022
    2022
    Citations: 49
  • Fabrication, structural and biological characterization of zinc-containing bioactive glasses and their use in membranes for guided bone regeneration
    SR Gavinho, AS Pádua, I Sá-Nogueira, JC Silva, JP Borges, LC Costa, ...
    Materials 16 (3), 956 , 2023
    2023
    Citations: 36
  • Chitosan scaffolds with mesoporous hydroxyapatite and mesoporous bioactive glass
    AS Pádua, L Figueiredo, JC Silva, JP Borges
    Progress in Biomaterials 12 (2), 137-153 , 2023
    2023
    Citations: 33
  • Bioactive Glass Modified with Zirconium Incorporation for Dental Implant Applications: Fabrication, Structural, Electrical, and Biological Analysis
    I Hammami, SR Gavinho, AS Pádua, I Sá-Nogueira, JC Silva, JP Borges, ...
    International Journal of Molecular Sciences 24 (13), 10571 , 2023
    2023
    Citations: 31
  • Extensive investigation on the effect of niobium insertion on the physical and biological properties of 45S5 bioactive glass for dental implant
    I Hammami, SR Gavinho, AS Pádua, MC Lança, JP Borges, JC Silva, ...
    International Journal of Molecular Sciences 24 (6), 5244 , 2023
    2023
    Citations: 29
  • Antibacterial biomaterial based on bioglass modified with copper for implants coating
    I Hammami, SR Gavinho, SK Jakka, MA Valente, MPF Graça, AS Pádua, ...
    Journal of Functional Biomaterials 14 (7), 369 , 2023
    2023
    Citations: 27
  • Green sol–gel synthesis of iron oxide nanoparticles for magnetic hyperthermia applications
    J Jesus, J Regadas, B Costa, J Carvalho, A Pádua, C Henriques, ...
    Pharmaceutics 16 (12), 1578 , 2024
    2024
    Citations: 18
  • In Vitro Characterization of Doped Bioglass 45S5/HAp Coatings Obtained by CoBlast TM Deposition
    AS Pádua, SR Gavinho, T Vieira, I Hammami, JC Silva, JP Borges, ...
    Coatings 13 (10), 1775 , 2023
    2023
    Citations: 11
  • Influence of the Particle Size on the Electrical, Magnetic and Biological Properties of the Bioglass ® Containing Iron Oxide
    JS Regadas, SR Gavinho, SS Teixeira, JV de Jesus, AS Pádua, JC Silva, ...
    Magnetochemistry 9 (9), 209 , 2023
    2023
    Citations: 10
  • Synthesis and Characterization of Iron Containing Bioactive Glass for Implants
    I Hammami, SR Gavinho, AS Pádua, MPF Graça, JC Silva
    2022 E-Health and Bioengineering Conference (EHB), 1-4 , 2022
    2022
    Citations: 9
  • Influence of zirconium dioxide (ZrO 2 ) and magnetite (Fe 3 O 4 ) additions on the structural, electrical, and biological properties of Bioglass ® for metal implant coatings
    I Hammami, MP Fernandes Graça, SR Gavinho, JS Regadas, SK Jakka, ...
    Frontiers in Bioengineering and Biotechnology 13, 1537856 , 2025
    2025
    Citations: 8
  • Polycaprolactone/Doped Bioactive Glass Composite Scaffolds for Bone Regeneration
    AS Pádua, MPF Graça, JC Silva
    Journal of Functional Biomaterials 16 (6), 200 , 2025
    2025
    Citations: 7
  • Hydroxyapatite-Barium Titanate Biocoatings Using Room Temperature Coblasting
    IJG Dias, AS Pádua, EA Pires, JPMR Borges, JC Silva, MC Lança
    Crystals 13 (4), 579 , 2023
    2023
    Citations: 5
  • Developing thermoresponsive p (NIPAAm-HMAAm) electrospun nanofibers for on-demand drug release of doxorubicin
    A Gonçalves, SN Fernandes, AS Pádua, JC Silva, JP Borges, M Castilho, ...
    Journal of Drug Delivery Science and Technology 112, 107244 , 2025
    2025
    Citations: 4
  • Electrospun poly (N-vinylpyrrolidone) membranes with Ag nanoparticles for wound dressings: Production and characterization
    AS Pádua, RM Rosa, T Vieira, C Henriques, JC Silva
    Journal of Drug Delivery Science and Technology 101, 106303 , 2024
    2024
    Citations: 4
  • Electrospun membranes from natural polymers with Quercetin: design and characterization, antioxidant and antimicrobial activity, and potential for skin reinnervation in chronic …
    C Correia, AS Pádua, C Matela, IC Gonçalves, P Soares, C Henriques, ...
    International Journal of Pharmaceutics, 126062 , 2025
    2025
    Citations: 3
  • Tantalum doped bioactive glass: towards a pro-regenerative and antibacterial response
    AS Pádua, SR Gavinho, MPF Graça, I Sá-Nogueira, JC Silva
    Materials Proceedings 8 (1), 51 , 2022
    2022
    Citations: 3
  • Electrospun membranes from natural polymers with Quercetin
    C Correia, AS Pádua, C Matela, IC Gonçalves, P Soares, C Henriques, ...
    2025
  • Electrospun poly (N-vinylpyrrolidone) membranes with Ag nanoparticles for wound dressings
    AS Pádua, RM Rosa, T Vieira, C Henriques, JC Silva
    2024

Industry, Institute, or Organisation Collaboration

Master dissertation in collaboration with BioCeramed R&D department, led by PhD Ligia Figueiredo and sponsored by PhD Eduardo Pires, under the FCT supervision of PhD Prof. João Paulo Borges.