Potential electrochemical reactions provoked by prolonged electrical stimulation and neuromodulation: in vitro porcine model Jonathan Jenkin Tsui, Jeremy Hopkin Tsui Regional Anesthesia and Pain Medicine, 2025 Recent neuromodulation studies used repurposed low-frequency (1–5 Hz) monophasic nerve localization stimulators of 200 µs up to 1 mA[1][1] or specialized high-frequency (100 Hz) biphasic chronic pain stimulators of 200 µs up to 30 mA[2][2] for acute pain management. Reactive particles (H+
The impact of relocation of chronic pain service from hospital setting to community centre on patient experience: a single-centre audit Jonathan Jenkin Tsui, Veronica Davey, Lesley Colvin British Journal of Pain, 2018 Background and aims: The Lothian Chronic Pain Service relocated from a university teaching hospital (Western General Hospital (WGH)) to a community centre (Leith Community Treatment Centre (LCTC)) in 2015. Transportation and geographical location were noted by staff to be potential challenges that could negatively impact on the patient experience. The objective of this study is to evaluate how relocating pain clinic from an urban-based hospital to a peripheral community centre on patient experience. Methods: An assessment and audit of the impact of the relocation on the Patient-Reported Experience Measure (PREM) of pain services was conducted. Using a nationally developed questionnaire, the patient-reported experience from LCTC was prospectively collected in 2016 and was compared to historical data obtained from WGH in 2014 by National Health Service (NHS) Scotland. All patients attending Lothian Chronic Pain Service clinics were deemed eligible for the audit. Patient demographics were compared between the two data sets. The impact of patient deprivation on patient experience was investigated using the Scottish Index of Multiple Deprivation (SIMD16). Results: Data from 111 patients from LCTC were compared to 206 patients from WGH. Percentage of patients rating care as ‘excellent’ was found to be significantly greater at LCTC than WGH (0.0049). However, overall patient rating of care from LCTC was not significantly different from WGH data and ratings were higher at LCTC. No correlation was found between patient deprivation and PREM. Conclusion: There is no clear evidence that PREM was negatively affected by the move from a university teaching hospital to a community setting. As this only reported experiences of patients who attended the service, further studies may be warranted to investigate the impact of patient nonattendance.
Is top-down therapy a more effective alternative to conventional step-up therapy for crohn’s disease? Jonathan Jenkin Tsui Annals of Gastroenterology, 2018 The management of Crohn's disease involves immunosuppressive protocols in a step-up approach that progresses through a therapeutic pyramid with several tiers of medication. Medications at the top are considered more potent but present greater risk. A new top-down approach to therapy inverts this procedure, using top-tier drugs for initial treatment. A critical appraisal of the current literature relating to top-down therapy was performed to evaluate its merit. A literature search was conducted on PubMed, Ovid, and PubMed Central to identify studies of the efficacy of top-down therapy. Papers were appraised critically using the Scottish Intercollegiate Guidelines Network score to evaluate current evidence for the use of top-down therapy. Nineteen studies were identified, including six randomized controlled trials, thirteen cohort studies, and two cost-benefit studies. Early combined therapy involving both biologics and immunomodulators was found to be effective at improving patient outcomes; however, early biologics alone were not shown to have a clear benefit over step-up therapy. Likewise, the early use of immunomodulators alone showed inconsistent results with respect to efficacy in terms of both remission and surgical outcomes. Evidence for application in pediatric populations was also inconclusive. The cost-benefit analyses found that top-down therapy merits investigation, as it proved to be economical given current data. Top-down therapy has the potential of being a viable alternative to step-up therapy, but further studies are needed to determine the most appropriate patients to receive this treatment.
The Frequency of Clinic Visits Was Not Associated with Medication Adherence or Outcome in Children with Inflammatory Bowel Diseases Cheryl Kluthe, Jenkin Tsui, Donald Spady, Matthew Carroll, Eytan Wine, Hien Quoc Huynh Canadian Journal of Gastroenterology and Hepatology, 2018 Background. Medication nonadherence is a challenge in pediatric patients with inflammatory bowel diseases (IBD). Poor adherence can result in disease flare-ups, disease complicationstherapy escalation, and the need for corticosteroids. The aim was to determine if clinic visit frequency was associated with treatment adherence. Methods. A retrospective chart review of patients attending the Edmonton Pediatric IBD Clinic (EPIC) at the Stollery Children’s Hospital from January 2012 to December 2013 was completed. Correlations were made between frequency of clinic visit, percentage of prescriptions filled, percentage of requisitioned blood work completed, rural or urban residence, and steroid-free remission status of patients for the 6 months after the chart review. Results. 127 patients were reviewed with 82 patients diagnosed with Crohn’s disease (CD) and 46 with ulcerative colitis (UC) which included one IBD-Unclassified. Mean age at diagnosis is 9.17 years and median duration of follow-up is 3.2 years. Almost all patients on infliximab infusions received them “within window.” Immunomodulator median adherence rate was 88%. 5-ASA adherence was 82%. A median of 67% of patients had blood work completed as requested. Clinic visit frequency was not associated with adherence to blood work or to medications. Duration of disease was the only independent factor found to be associated with a reduction in blood work and immunomodulator adherence (“OR 0.86 and 95% CI: 0.74–0.99” and “OR 0.82 and 95% CI: 0.71–0.97”) per year, respectively. Patients who remained corticosteroid-free in the 6 months after the 2 years’ adherence review had an overall median medication adherence rate of 86% compared to only 53% for those who relapsed and required corticosteroids (p=0.01). Conclusion. Clinic visit frequency was not associated with patient adherence to medications or blood work. However, disease duration was found to be associated with medication adherence. Adherent patients were more likely to remain in steroid-free remission.
ABC Diaphragmatic Evaluation for neonates Ban C.H. Tsui, Jenkin Tsui Paediatric Anaesthesia, 2016 Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Bridging language gaps: a study of linguistic transfer perceptions among Chinese medical students in an English-medium instruction program JJ Tsui, EY Li, CS Xie, Z Zhu, X Yin, BCH Tsui, AKY Siu Frontiers in Medicine 13, 1798909 , 2026 2026
Potential electrochemical reactions provoked by prolonged electrical stimulation and neuromodulation: in vitro porcine model JJ Tsui, JH Tsui Regional Anesthesia and Pain Medicine, rapm-2022-104234 , 2023 2023
A modified Tuohy needle tip design for catheter over needle catheterization: in vitro testing JJ Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 68 (5), 747-748 , 2021 2021
An improved Tuohy needle tip design for Catheter Over Needle Catheterization: In Vitro Testing B Tsui, J Tsui, J Tsui ANESTHESIA AND ANALGESIA 130, 857-858 , 2020 2020
The impact of relocation of chronic pain service from hospital setting to community centre on patient experience: a single-centre audit JJ Tsui, V Davey, L Colvin British Journal of Pain 12 (4), 220-229 , 2018 2018
Is top-down therapy a more effective alternative to conventional step-up therapy for Crohn’s disease? JJ Tsui, HQ Huynh Annals of gastroenterology 31 (4), 413 , 2018 2018 Citations: 105
Research Article The Frequency of Clinic Visits Was Not Associated with Medication Adherence or Outcome in Children with Inflammatory Bowel Diseases C Kluthe, J Tsui, D Spady, M Carroll, E Wine, HQ Huynh 2018
The frequency of clinic visits was not associated with medication adherence or outcome in children with inflammatory bowel diseases C Kluthe, J Tsui, D Spady, M Carroll, E Wine, HQ Huynh Canadian Journal of Gastroenterology and Hepatology 2018 (1), 4687041 , 2018 2018 Citations: 11
Proper use and interpretation of diaphragmatic ultrasonography RV Sondekoppam, L Naik, J Tsui, BCH Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 64 (5), 548-549 , 2017 2017 Citations: 9
Less is more: minimal interventions in regional anesthesia BC Tsui, J Tsui Curr Opin Anaesthesiol 30 (5), 598-604 , 2017 2017 Citations: 6
An ultrasound-guided ABCDE approach with a sniff test to evaluate diaphragmatic function without acoustic windows LYS Naik, RV Sondekoppam, J Jenkin Tsui, BCH Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 63 (10), 1199-1200 , 2016 2016 Citations: 20
A novel systematic ABC approach to D iaphragmatic E valuation (ABCDE) JJ Tsui, BCH Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 63 (5), 636-637 , 2016 2016 Citations: 44
Generation of tidal volume via gentle chest pressure in children over one year old BCH Tsui, S Horne, J Tsui, GN Corry Resuscitation 92, 148-153 , 2015 2015 Citations: 15
O-015 YI; The Impact of Clinic Visits and Disease Activity on Adherence Rates in Children With Inflammatory Bowel Diseases C Kluthe, H Hien, M Carroll, D Spady, W Eytan, T Jenkin Inflammatory Bowel Diseases 20, S9-S9 , 2014 2014
Moins de fuites et de déplacements avec un cathéter par-dessus l’aiguille qu’avec un cathéter à travers l’aiguille pour un bloc nerveux périphérique: une étude ex vivo BCH Tsui, J Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 59, 655-661 , 2012 2012
Less leakage and dislodgement with a catheter-over-needle versus a catheter-through-needle approach for peripheral nerve block: an ex vivo study BCH Tsui, J Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 59 (7), 655-661 , 2012 2012 Citations: 45
A flexible gel pad as an effective medium for scanning irregular surface anatomy BCH Tsui, J Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 59 (2), 226-227 , 2012 2012 Citations: 24
Rapid percutaneous tracheal catheterization using electrical guidance BCH Tsui, J Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 59 (1), 116-117 , 2012 2012 Citations: 3
Paramedian thoracic epidural training model BCH Tsui, J Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 58 (11), 1051-1052 , 2011 2011 Citations: 7
MOST CITED SCHOLAR PUBLICATIONS
Is top-down therapy a more effective alternative to conventional step-up therapy for Crohn’s disease? JJ Tsui, HQ Huynh Annals of gastroenterology 31 (4), 413 , 2018 2018 Citations: 105
Less leakage and dislodgement with a catheter-over-needle versus a catheter-through-needle approach for peripheral nerve block: an ex vivo study BCH Tsui, J Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 59 (7), 655-661 , 2012 2012 Citations: 45
A novel systematic ABC approach to D iaphragmatic E valuation (ABCDE) JJ Tsui, BCH Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 63 (5), 636-637 , 2016 2016 Citations: 44
A flexible gel pad as an effective medium for scanning irregular surface anatomy BCH Tsui, J Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 59 (2), 226-227 , 2012 2012 Citations: 24
An ultrasound-guided ABCDE approach with a sniff test to evaluate diaphragmatic function without acoustic windows LYS Naik, RV Sondekoppam, J Jenkin Tsui, BCH Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 63 (10), 1199-1200 , 2016 2016 Citations: 20
Generation of tidal volume via gentle chest pressure in children over one year old BCH Tsui, S Horne, J Tsui, GN Corry Resuscitation 92, 148-153 , 2015 2015 Citations: 15
The frequency of clinic visits was not associated with medication adherence or outcome in children with inflammatory bowel diseases C Kluthe, J Tsui, D Spady, M Carroll, E Wine, HQ Huynh Canadian Journal of Gastroenterology and Hepatology 2018 (1), 4687041 , 2018 2018 Citations: 11
Proper use and interpretation of diaphragmatic ultrasonography RV Sondekoppam, L Naik, J Tsui, BCH Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 64 (5), 548-549 , 2017 2017 Citations: 9
Paramedian thoracic epidural training model BCH Tsui, J Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 58 (11), 1051-1052 , 2011 2011 Citations: 7
Less is more: minimal interventions in regional anesthesia BC Tsui, J Tsui Curr Opin Anaesthesiol 30 (5), 598-604 , 2017 2017 Citations: 6
Rapid percutaneous tracheal catheterization using electrical guidance BCH Tsui, J Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 59 (1), 116-117 , 2012 2012 Citations: 3
Reusable phantom with feedback signal for ultrasound needle tip control BCH Tsui, J Tsui Regional Anesthesia & Pain Medicine 36 (6), 630-631-630-631 , 2011 2011 Citations: 2
Bridging language gaps: a study of linguistic transfer perceptions among Chinese medical students in an English-medium instruction program JJ Tsui, EY Li, CS Xie, Z Zhu, X Yin, BCH Tsui, AKY Siu Frontiers in Medicine 13, 1798909 , 2026 2026
Potential electrochemical reactions provoked by prolonged electrical stimulation and neuromodulation: in vitro porcine model JJ Tsui, JH Tsui Regional Anesthesia and Pain Medicine, rapm-2022-104234 , 2023 2023
A modified Tuohy needle tip design for catheter over needle catheterization: in vitro testing JJ Tsui Canadian Journal of Anesthesia/Journal canadien d'anesthésie 68 (5), 747-748 , 2021 2021
An improved Tuohy needle tip design for Catheter Over Needle Catheterization: In Vitro Testing B Tsui, J Tsui, J Tsui ANESTHESIA AND ANALGESIA 130, 857-858 , 2020 2020
The impact of relocation of chronic pain service from hospital setting to community centre on patient experience: a single-centre audit JJ Tsui, V Davey, L Colvin British Journal of Pain 12 (4), 220-229 , 2018 2018
Research Article The Frequency of Clinic Visits Was Not Associated with Medication Adherence or Outcome in Children with Inflammatory Bowel Diseases C Kluthe, J Tsui, D Spady, M Carroll, E Wine, HQ Huynh 2018
O-015 YI; The Impact of Clinic Visits and Disease Activity on Adherence Rates in Children With Inflammatory Bowel Diseases C Kluthe, H Hien, M Carroll, D Spady, W Eytan, T Jenkin Inflammatory Bowel Diseases 20, S9-S9 , 2014 2014