JURAINA ABD-JAMIL

@um.edu.my

TROPICAL INFECTIOUS DISEASES RESEARCH AND EDUCATION CENTRE (TIDREC)
UNIVERSITI MALAYA

EDUCATION

Master in Medical Sciences (Molecular and Cell Biology), Universiti Malaya (UM)

BACHELOR OF ARTS AND LIBERAL SCIENCE (Microbiology)
University of Illinois Urbana Champaign

RESEARCH, TEACHING, or OTHER INTERESTS

Microbiology, Virology, Infectious Diseases
35

Scopus Publications

1063

Scholar Citations

18

Scholar h-index

22

Scholar i10-index

Scopus Publications

  • Decrease in RT-PCR Ct values among SARS-CoV-2 positive samples during themergence of B.1.617.2 (Delta) variant in Malaysia
    Che-Kamaruddin N.
    Tropical Biomedicine, 2025
    Reverse transcription-polymerase chain reaction (RT-PCR) cycle threshold (Ct) value in detecting the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection is inversely proportionate to the virus load in the patient's specimen. These values could be beneficial in the epidemic trajectory at the population level. The SARS-CoV-2 B.1.617.2 (Delta) variant which emerged in late 2020, caused an unprecedented exponential increase in SARS-CoV-2 infection cases worldwide. In Malaysia, the surge in coronavirus disease 2019 (COVID-19) cases and the inclining positivity rate contributed to the epidemic waves in late May 2021. Sudden surge in cases was suggested to be associated with increased transmission caused by the emergence of the B.1.617.2 variant. In the present study, Ct value distribution of the positive COVID-19 samples from 2020 and 2021 was tabulated against SARS-CoV-2 genomic variants determined from genomic sequencing. A significant decreasing pattern of median Ct values from overall 2020 and 2021 samples was evident (p<0.01). However, notable variability was observed in the Ct values between 2020 and 2021, which samples showing lower median Ct values in 2021. The percentages of SARS-CoV-2 genomic variants B.1.36 and B.1.524 were 31.6% and 68.4%, respectively, for samples obtained in October and December 2020. Whereas samples obtained in June and July 2021 were 100% of the B.1.617.2 variant. The population neutralizing antibody against SARS-CoV-2 during the initial peak of B.1.617.2 was low, however, increased during the B.1.617.2 wave. A decreasing trend in the Ct value distribution from samples tested in our laboratory correlated well with the increasing weekly COVID-19 cases reported by the Malaysia national data, which was subsequently attributed to the emergence of B.1.617.2 variant. This study proposes that analyzing Ct value distribution in screened SARS-CoV-2 samples could reveal population-level transmission dynamics and emerging variants. Coupled with genomic sequencing, it supports early control strategies against new SARS-CoV-2 strains.
  • Effectiveness of Dengue Awareness Calendar on Indigenous Population: Impact on Knowledge, Belief and Practice
    Li Ping Wong, Arulvani Rajandra, Juraina Abd Jamil, Sazaly AbuBakar, Yulan Lin, Hai Yen Lee
    Healthcare Switzerland, 2023
    Background: Dengue is prevalent among the indigenous community due to impoverished living conditions near the forest fringe areas and lack of health awareness. The study aims to determine the effect of a dengue awareness calendar on knowledge, belief, and practices (KBP) among the indigenous population. Method: A cross-sectional study was conducted in nine selected indigenous villages in Selangor, Malaysia. A dengue awareness calendar was distributed to the indigenous communities after pre-intervention. The KBP scores were compared between the pre-and post-intervention. Result: A total of 609 paired responses were obtained. Knowledge, perceived severity, cues to action, self-efficacy, and prevention practices were significantly improved after the intervention (p &gt; 0.00). Participants with primary (Odds Ratio (OR) 2.627; 95% CI 1.338–5.160) and secondary level education (OR 2.263; 95% Cl 1.126–4.550) reported a high increment in practices score. High increments in dengue knowledge scores (OR 2.190; 95% CI 1.521–3.757, p &lt; 0.00) were significantly more likely to report a high increment in practices score. Housewives (OR 0.535; 95% Cl 0.289–0.950), perceived severity (OR 0.349; 95% CI 0.184–0.662), and perceived susceptibility (OR 0.474; 95% CI 0.286–0.785) were significantly less likely to report an increment in prevention practices score. Conclusion: Findings inferred that the dengue awareness calendar significantly improved knowledge and practices. Our findings revealed the effectiveness of the dengue awareness calendar in dengue prevention among indigenous communities.
  • Early diagnostic indicators of dengue versus other febrile illnesses in Asia and Latin America (IDAMS study): a multicentre, prospective, observational study
    Kerstin D Rosenberger, Lam Phung Khanh, Frank Tobian, Ngoun Chanpheaktra, Varun Kumar, Lucy Chai See Lum, Jameela Sathar, Ernesto Pleités Sandoval, Gabriela M Marón, Ida Safitri Laksono, Yodi Mahendradhata, Malabika Sarker, Ridwanur Rahman, Andrea Caprara, Bruno Souza Benevides, Ernesto T A Marques, Tereza Magalhaes, Patrícia Brasil, Guilherme Amaral Calvet, Adriana Tami, Sarah E Bethencourt, Tam Dong Thi Hoai, Kieu Nguyen Tan Thanh, Ngoc Tran Van, Nam Nguyen Tran, Viet Do Chau, Sophie Yacoub, Kinh Nguyen Van, María G Guzmán, Pedro A Martinez, Quyen Nguyen Than Ha, Cameron P Simmons, Bridget A Wills, Ronald B Geskus, Thomas Jaenisch, Zabir Hasan, Kilma Wanderley Lopes Gomes, Lyvia Patricia Soares Mesquita, Cynthia Braga, Priscila M.S. Castanha, Marli T. Cordeiro, Luana Damasceno, Bophal Chuop, Sonyrath Ouk, Reaksmey Sin, Sopheary Sun, Mayling Alvarez Vera, Guillermo Barahona, Bladimir Cruz, Dorothea Beck, Roger Gaczkowski, Thomas Junghanss, Ivonne Morales, Marius Wirths, Santha Kumari Natkunam, Bee Kiau Ho, Sazaly AbuBakar, Juraina Abd-Jamil, Sharifah Faridah Syed Omar, Erley F. Lizarazo, María F. Vincenti-González, Erley F. Lizarazo, Robert Tovar, María F. Vincenti-González, Tam Cao Thi, Hong Dinh Thi Tri, Huy Huynh Le Anh, Duyen Huynh Thi Le, Thanh Lai Thi Cong, Van Nguyen Thi Hong, Linh Nguyen Thi My, Thuy Tran Thi Nhu, Thuy Truong Thi Thu, Nuoi Banh Thi, Trinh Huynh Lam Thuy, Hiep Nguyen Thi Thu, Van Tran Thi Kim, Luan Vo Thanh, Bich Dang Thi, Huong Dinh Thi Thu, Huy Dinh Van, Huyen Nguyen Nguyen, Huong Vu Thi Thu
    Lancet Global Health, 2023
    BACKGROUND: Improvements in the early diagnosis of dengue are urgently needed, especially in resource-limited settings where the distinction between dengue and other febrile illnesses is crucial for patient management. METHODS: In this prospective, observational study (IDAMS), we included patients aged 5 years and older with undifferentiated fever at presentation from 26 outpatient facilities in eight countries (Bangladesh, Brazil, Cambodia, El Salvador, Indonesia, Malaysia, Venezuela, and Viet Nam). We used multivariable logistic regression to investigate the association between clinical symptoms and laboratory tests with dengue versus other febrile illnesses between day 2 and day 5 after onset of fever (ie, illness days). We built a set of candidate regression models including clinical and laboratory variables to reflect the need of a comprehensive versus parsimonious approach. We assessed performance of these models via standard measures of diagnostic values. FINDINGS: Between Oct 18, 2011, and Aug 4, 2016, we recruited 7428 patients, of whom 2694 (36%) were diagnosed with laboratory-confirmed dengue and 2495 (34%) with (non-dengue) other febrile illnesses and met inclusion criteria, and were included in the analysis. 2703 (52%) of 5189 included patients were younger than 15 years, 2486 (48%) were aged 15 years or older, 2179 (42%) were female and 3010 (58%) were male. Platelet count, white blood cell count, and the change in these variables from the previous day of illness had a strong association with dengue. Cough and rhinitis had strong associations with other febrile illnesses, whereas bleeding, anorexia, and skin flush were generally associated with dengue. Model performance increased between day 2 and 5 of illness. The comprehensive model (18 clinical and laboratory predictors) had sensitivities of 0·80 to 0·87 and specificities of 0·80 to 0·91, whereas the parsimonious model (eight clinical and laboratory predictors) had sensitivities of 0·80 to 0·88 and specificities of 0·81 to 0·89. A model that includes laboratory markers that are easy to measure (eg, platelet count or white blood cell count) outperformed the models based on clinical variables only. INTERPRETATION: Our results confirm the important role of platelet and white blood cell counts in diagnosing dengue, and the importance of serial measurements over subsequent days. We successfully quantified the performance of clinical and laboratory markers covering the early period of dengue. Resulting algorithms performed better than published schemes for distinction of dengue from other febrile illnesses, and take into account the dynamic changes over time. Our results provide crucial information needed for the update of guidelines, including the Integrated Management of Childhood Illness handbook. FUNDING: EU's Seventh Framework Programme. TRANSLATIONS: For the Bangla, Bahasa Indonesia, Portuguese, Khmer, Spanish and Vietnamese translations of the abstract see Supplementary Materials section.
  • A TaqMan minor groove binder probe-based quantitative reverse transcription polymerase chain reaction for detection and quantification of chikungunya virus
    Lim Y.Z.
    Tropical Biomedicine, 2023
    Chikungunya virus (CHIKV) is a mosquito-borne alphavirus with widespread distribution across the globe. Since 2016, CHIKV re-emerged in several countries including Indian subcontinent and Southeast Asia. A proper diagnostic tool for early diagnosis of CHIKV infection is crucial to facilitate patient management and control virus transmission at the earliest stage of outbreak. Therefore, a TaqMan minor groove binder (MGB) probe-based quantitative reverse transcription polymerase chain reaction (qRT-PCR) assay was developed to detect and quantify the CHIKV. The primers and probe were designed based on a conserved genomic region of 730 global CHIKV sequences that is located between nsP1 and nsP2 genes. The nucleotide mismatches of primers and probe with 730 global CHIKV sequences and 13 alphaviruses were then analysed in silico. In this study, the last 5 nucleotides at 3' end of primers and 5' end of probe were considered to be the critical regions for priming. In silico analysis revealed that the critical regions of primers and probe were at least 99.6% matched with the 730 global CHIKV sequences. Besides, the primers and probe showed at least 5/20 (25.0%) and 4/17 (23.5%) nucleotide mismatches with 13 alphaviruses respectively. The amplification efficiency of qRT-PCR assay was 100.59% (95% CI= 93.06, 109.33) with a R 2 score of 0.957. Its limit of detection (LOD) at 95% probability level was 16.6 CHIKV RNA copies (95% CI= 12.9, 28.9). The qRT-PCR assay was specific to CHIKV without cross-reacting with all dengue virus serotypes, Getah virus, Tembusu virus and Zika virus. The diagnostic results of qRT-PCR assay were perfectly agreed (k=1.000, p=0.003) with a commercial trioplex assay, with sensitivity of 100% (95% CI= 61, 100) and specificity of 100% (95% CI= 44, 100). Overall, the developed qRT-PCR assay is ideal for rapid, sensitive and specific detection as well as quantification of CHIKV.
  • Epidemiological serosurvey of chikungunya fever post outbreak at Tanjung Sepat, Malaysia
    Chee-Sieng Khor, Boon-Teong Teoh, Sing-Sin Sam, Hooi-Yuen Khoo, Noor-Syahida Azizan, AsmaAnati CheMatSeri, Kim-Ling Chin, Zur-Raiha Hamim, Noor-Adila Mohamed-Romai-Noor, Che-Norainon Yaacob, Juraina Abd-Jamil, Hai-Yen Lee, Yih-Harng Soh, Sazaly AbuBakar
    Journal of Infection in Developing Countries, 2023
    Introduction: Chikungunya fever is a mosquito-borne viral disease that usually presents with prominent arthralgia. An outbreak of chikungunya fever was reported in Tanjung Sepat, Malaysia in 2019. The outbreak was limited in size with a low number of cases being reported. The present study sought to determine the possible variables that could have affected the transmission of the infection. Methodology: A cross-sectional study involving 149 healthy adult volunteers from Tanjung Sepat was performed soon after the outbreak had subsided. All the participants donated blood samples and completed the questionnaires. Laboratory detection of anti-CHIKV IgM and IgG antibodies was performed using enzyme-linked immunoassays (ELISA). Risk factors associated with chikungunya seropositivity were determined using logistic regression. Results: The majority (72.5%, n = 108) of the study participants tested positive for CHIKV antibodies. Only 8.3% (n = 9) of the participants out of all the seropositive volunteers had an asymptomatic infection. Participants who resided with a febrile (p &lt; 0.05, Exp(B) = 2.2, confidence interval [CI] 1.3-3.6) or a CHIKV-diagnosed person (p &lt; 0.05, Exp(B) = 2.1, CI 1.2-3.6) in the same household were found likely to be tested positive for CHIKV antibodies. Conclusions: Findings from the study support that asymptomatic CHIKV infections and indoor transmission occurred during the outbreak. Hence, widespread community testing and indoor use of mosquito repellent are among the possible measures that can be implemented to reduce CHIKV transmission during an outbreak.
  • MERS-CoV seroconversion amongst Malaysian Hajj pilgrims returning from the Middle East, 2016–2018: results from the MERCURIAL multiyear prospective cohort study
    Jefree Johari, Robert D. Hontz, Brian L. Pike, Tupur Husain, Norhayati Rusli, Rozainanee Mohd-Zain, Vunjia Tiong, Hai-Yen Lee, Boon-Teong Teoh, Sing-Sin Sam, Chee-Sieng Khor, Shih-Keng Loong, Juraina Abd-Jamil, Siti-Sarah Nor'e, Hasmawati Yahaya, Naim Che-Kamaruddin, Jose A. Garcia-Rivera, Sazaly AbuBakar
    Emerging Microbes and Infections, 2023
    Prospective cohort study to investigate the potential exposure to the Middle East Respiratory Syndrome-Coronavirus (MERS-CoV) following Hajj pilgrims is still very limited. Here, we report the antibody seroconversion study results obtained from successive three years cohort studies (2016-2018) involving the Malaysian Hajj pilgrims returning from the Middle East. A cohort study of Hajj pilgrims from Malaysia enrolled 2,863 participants from 2016-2018, all of whom consented to provide paired blood samples for both pre- and post-Hajj travel to the Middle East. ELISAs and micro-neutralization assays were performed to detect the presence of MERS-CoV IgG antibodies. Sociodemographic data, symptoms experienced during Hajj, and history of exposure to camels or camel products were recorded using structured pre- and post-Hajj questionnaires. A 4-fold increase in anti-MERS-CoV IgG between paired pre-Hajj and post-Hajj serum samples in twelve participants was observed. None of the twelve ELISA-positive sera had detectable levels of virus-neutralizing antibodies. All reportedly had mild symptoms of respiratory symptoms at a certain point during the pilgrimage, implying mild or asymptomatic infections. No association between post-Hajj serum positivity and a history of exposure to camels or camel products was obtained. Findings from the study suggest that serologic conversion to MERS-CoV occurred in at least 0.6% of the Hajj pilgrims returning from the Middle East. Since all the seroconvertants had mild to no symptoms during the sampling period, it highlights the likelihood of occurrence of only low infectivity spillover infections among the Hajj pilgrims.
  • Development of a TaqMan minor groove binding probe-based quantitative reverse transcription polymerase chain reaction for the detection and quantification of Zika virus
    Chin K.L.
    Tropical Biomedicine, 2022
    Zika virus (ZIKV) infection has emerged as a global health concern following epidemic outbreaks of severe neurological disorders reported in Pacific and Americas since 2016. Therefore, a rapid, sensitive and specific diagnostic test for ZIKV infection is critical for the appropriate patient management and the control of disease spread. A TaqMan minor groove binding (MGB) probe-based quantitative reverse transcription-polymerase chain reaction (qRT-PCR) assay was developed based on the conserved sequence regions of 463 ZIKV NS2B genes. The designed ZIKV qRT-PCR assay was evaluated for its detection limit, strain coverage and cross-reactivity. We further assessed the clinical applicability of qRT-PCR assay for ZIKV RNA detection using a total 18 simulated clinical specimens. The detection limit of the qRT-PCR assay was 11.276 ZIKV RNA copies at the 95% probability level (probit analysis, p<= 0.05). Both Asian and African ZIKV strains were detected by the qRT-PCR assay without cross-reacting with DENV-1, DENV-2, DENV-3, DENV-4, CHIKV, JEV, LGTV, GETV and SINV. The qRT-PCR assay demonstrated a perfect agreement (k = 1.000, P < 0.001) with the reference assay; the sensitivity and specificity of the qRT-PCR assay were 100% (95% CI= 79.6-100) and 100% (95% CI= 43.9-100) respectively. The qRT-PCR assay developed in this study is a useful diagnostic tool for the broad coverage detection and quantification of both the Asian and African ZIKV strains.
  • Group IV Getah Virus in Culex Mosquitoes, Malaysia
    Sing-Sin Sam, Noor-Adila Mohamed-Romai-Noor, Boon-Teong Teoh, Zur-Raiha Hamim, Hoi-Ying Ng, Juraina Abd-Jamil, Chee-Sieng Khor, Sharifah-Syed Hassan, Hamdan Ahmad, Sazaly AbuBakar
    Emerging Infectious Diseases, 2022
    A new Getah virus (GETV) strain, B254, was isolated from Culex fuscocephalus mosquitoes captured at Mount Ophir, Malaysia, in 2012. Phylogenetic analyses revealed that GETV B254 is distinct from the old Malaysia GETV MM2021 strain but closely related to group IV GETV from Russia (LEIV16275Mag), China (YN12031), and Thailand (GETV/SW/Thailand/2017).
  • The Risk of Transfusion-Transmitted Hepatitis E Virus: Evidence from Seroprevalence Screening of Blood Donations
    Li Ping Wong, Hai Yen Lee, Chee Sieng Khor, Juraina Abdul-Jamil, Haridah Alias, Noryati Abu-Amin, Murniwati Mat-Radzi, Nurul Ashila Rohimi, Hana Najian Mokhtardin, Sazaly AbuBakar, Zizheng Zheng, Ting Wu, Qinjian Zhao, Ningshao Xia
    Indian Journal of Hematology and Blood Transfusion, 2022
  • A 3d microfluidic elisa for the detection of severe dengue: Sensitivity improvement and vroman effect amelioration by edc–nhs surface modification
    Hinata Maeno, Pooi-Fong Wong, Sazaly AbuBakar, Ming Yang, Sing-Sin Sam, Juraina Jamil-Abd, Anusha Shunmugarajoo, Mahiran Mustafa, Rosaida Md Said, Eashwary Mageswaren, Azureen Azmel, Anilawati Mat Jelani
    Micromachines, 2021
    Serum is commonly used as a specimen in immunoassays but the presence of heterophilic antibodies can potentially interfere with the test results. Previously, we have developed a microfluidic device called: 3D Stack for enzyme-linked immunosorbent assay (ELISA). However, its evaluation was limited to detection from a single protein solution. Here, we investigated the sensitivity of the 3D Stack in detecting a severe dengue biomarker—soluble CD163 (sCD163)—within the serum matrix. To determine potential interactions with serum matrix, a spike-and-recovery assay was performed, using 3D Stacks with and without surface modification by an EDC–NHS (N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide/N-hydroxysuccinimide) coupling. Without surface modification, a reduced analyte recovery in proportion to serum concentration was observed because of the Vroman effect, which resulted in competitive displacement of coated capture antibodies by serum proteins with stronger binding affinities. However, EDC–NHS coupling prevented antibody desorption and improved the sensitivity. Subsequent comparison of sCD163 detection using a 3D Stack with EDC–NHS coupling and conventional ELISA in dengue patients’ sera revealed a high correlation (R = 0.9298, p &lt; 0.0001) between the two detection platforms. Bland–Altman analysis further revealed insignificant systematic error between the mean differences of the two methods. These data suggest the potentials of the 3D Stack for further development as a detection platform.
  • Emergence of B.1.524(G) SARS-CoV-2 in Malaysia during the third COVID-19 epidemic wave
    Kim-Kee Tan, Jia-Yi Tan, Jo-Ern Wong, Boon-Teong Teoh, Vunjia Tiong, Juraina Abd-Jamil, Siti-Sarah Nor’e, Chee-Sieng Khor, Jefree Johari, Che-Norainon Yaacob, Mulya-Mustika-Sari Zulkifli, AsmaAnati CheMatSeri, Nur-Hidayana Mahfodz, Noor Syahida Azizan, Sazaly AbuBakar
    Scientific Reports, 2021
  • Multiplex sequencing of sars-cov-2 genome directly from clinical samples using the ion personal genome machine (Pgm)
    Tan K.K.
    Tropical Biomedicine, 2021
  • Multiyear prospective cohort study to evaluate the risk potential of MERS-CoV infection among Malaysian Hajj pilgrims (MERCURIAL): A study protocol
    Jefree Johari, Robert D Hontz, Brian L Pike, Tupur Husain, Chee-Kheong Chong, Norhayati Rusli, Lokman-Hakim Sulaiman, Khebir Verasahib, Rozainanee Mohd Zain, Adzzie-Shazleen Azman, Chee Sieng Khor, Siti-Sarah Nor"e, Vunjia Tiong, Hai Yen Lee, Boon-Teong Teoh, Sing Sin Sam, Jing-Jing Khoo, Juraina Abd Jamil, Shih-Keng Loong, Che Norainon Yaacob, Nur-Hidayana Mahfodz, Noor Syahida Azizan, Nurul Asma Anati Che Mat Seri, Nurul-Farhana Mohd-Rahim, Habibi Hassan, Hasmawati Yahaya, Jose A Garcia-Rivera, Sazaly AbuBakar
    BMJ Open, 2021
  • Detection and confirmation of dengue pre- and postintroduction of dengue NS1-antigen test at the University Malaya Medical Centre: An observational study
    Juraina Abd‐Jamil, Noor‐Syahida Azizan, Nurul‐Asma‐Anati Che‐Mat‐Seri, Che‐Norainon Yaacob, Nur‐Izyan Samsudin, Nur‐Hidayana Mahfodz, Mulya‐Mustika‐Sari Zulkifli, Hooi‐Sim Poh, Boon‐Teong Teoh, Sazaly AbuBakar
    Journal of Medical Virology, 2021
  • Detecting dengue outbreaks in malaysia using geospatial techniques
    Syahrul Nellis, Shih Keng Loong, Juraina Abd-Jamil, Rosmadi Fauzi, Sazaly AbuBakar
    Geospatial Health, 2021
  • A reverse transcription loop-mediated isothermal amplification for broad coverage detection of Asian and African Zika virus lineages
    Boon-Teong Teoh, Kim-Ling Chin, Nur-Izyan Samsudin, Shih-Keng Loong, Sing-Sin Sam, Kim-Kee Tan, Chee-Sieng Khor, Juraina Abd-Jamil, Nurhafiza Zainal, Annelies Wilder-Smith, Keivan Zandi, Sazaly AbuBakar
    BMC Infectious Diseases, 2020
  • Dengue fever among febrile patients in Taiz City, Yemen during the 2016 war: Clinical manifestations, risk factors, and patients knowledge, attitudes, and practices toward the disease
    KhairAlah A. Alghazali, Boon-Teong Teoh, Sing-Sin Sam, Juraina Abd-Jamil, Jefree Johari, Wahib M. Atroosh, Mohammed A.K. Mahdy, Sazaly AbuBakar
    One Health, 2020
  • Possible Factors Influencing the Seroprevalence of Dengue among Residents of the Forest Fringe Areas of Peninsular Malaysia
    Juraina Abd-Jamil, Romano Ngui, Syahrul Nellis, Rosmadi Fauzi, Ai Lian Yvonne Lim, Karuthan Chinna, Chee-Sieng Khor, Sazaly AbuBakar
    Journal of Tropical Medicine, 2020
  • Dengue outbreak during ongoing civil war, taiz, yemen
    Emerging Infectious Diseases, 2019
  • Seroprevalence of borrelia burgdorferi among the indigenous people (Orang asli) of peninsular malaysia
    Chee-Sieng Khor, Habibi Hassan, Nurul-Farhana Mohd-Rahim, Josephine Rebecca Chandren, Siti-Sarah Nore, Jefree Johari, Shih-Keng Loong, Juraina Abd-Jamil, Jing-Jing Khoo, Hai-Yen Lee, Brian L Pike, Wong Li-Ping, Yvonne Ai-Lian Lim, Sazaly AbuBakar
    Journal of Infection in Developing Countries, 2019
  • A quantitative reverse transcription-polymerase chain reaction for detection of Getah virus
    Sing-Sin Sam, Boon-Teong Teoh, Cheah-Mun Chee, Noor-Adila Mohamed-Romai-Noor, Juraina Abd-Jamil, Shih-Keng Loong, Chee-Sieng Khor, Kim-Kee Tan, Sazaly AbuBakar
    Scientific Reports, 2018
  • Emergence of the Asian lineage dengue virus type 3 genotype III in Malaysia
    Kim-Kee Tan, Nurul-Izzani Zulkifle, Syuhaida Sulaiman, Sui-Ping Pang, NurAsyura NorAmdan, NorAziyah MatRahim, Juraina Abd-Jamil, Meng-Hooi Shu, Nor Muhammad Mahadi, Sazaly AbuBakar
    BMC Evolutionary Biology, 2018
  • Seroprevalence of Q Fever among the Indigenous People (Orang Asli) of Peninsular Malaysia
    Chee-Sieng Khor, Nurul-Farhana Mohd-Rahim, Habibi Hassan, Josephine Rebecca Chandren, Siti-Sarah Nore, Jefree Johari, Shih-Keng Loong, Juraina Abd-Jamil, Jing-Jing Khoo, Hai-Yen Lee, Brian L. Pike, Li Ping Wong, Yvonne Ai-Lian Lim, Keivan Zandi, Sazaly AbuBakar
    Vector Borne and Zoonotic Diseases, 2018
  • Disruption of predicted dengue virus type 3 major outbreak cycle coincided with switching of the dominant circulating virus genotype
    Kim-Kee Tan, Nurul-Izzani Zulkifle, Juraina Abd-Jamil, Syuhaida Sulaiman, Che Norainon Yaacob, Noor Syahida Azizan, Nurul Asma Anati Che Mat Seri, Nur Izyan Samsudin, Nur Hidayana Mahfodz, Sazaly AbuBakar
    Infection Genetics and Evolution, 2017
  • The Use of NS1 Rapid Diagnostic Test and qRT-PCR to Complement IgM ELISA for Improved Dengue Diagnosis from Single Specimen
    Boon-Teong Teoh, Sing-Sin Sam, Kim-Kee Tan, Jefree Johari, Juraina Abd-Jamil, Poh-Sim Hooi, Sazaly AbuBakar
    Scientific Reports, 2016
  • Evaluation of land cover and prevalence of dengue in Malaysia
    Tropical Biomedicine, 2015
  • Dengue death with evidence of hemophagocytic syndrome and dengue virus infection in the bone marrow
    Hasliana Azrah Ab-Rahman, Pooi-Fong Wong, Hafiz Rahim, Juraina Abd-Jamil, Kim-Kee Tan, Syuhaida Sulaiman, Chai-See Lum, Syarifah-Faridah Syed-Omar, Sazaly AbuBakar
    Springerplus, 2015
  • Colorimetric detection of dengue by single tube reverse-transcription-loop-mediated isothermal amplification
    Yee-Ling Lau, Meng-Yee Lai, Boon-Teong Teoh, Juraina Abd-Jamil, Jefree Johari, Sing-Sin Sam, Kim-Kee Tan, Sazaly AbuBakar
    Plos One, 2015
  • Comparison of real time reverse transcription-polymerase chain reaction assays for the detection of dengue virus
    Journal of the University of Malaya Medical Centre, 2013
  • Dengue virus type 1 clade replacement in recurring homotypic outbreaks
    Boon-Teong Teoh, Sing-Sin Sam, Kim-Kee Tan, Jefree Johari, Meng-Hooi Shu, Mohammed Bashar Danlami, Juraina Abd-Jamil, NorAziyah MatRahim, Nor Muhammad Mahadi, Sazaly AbuBakar
    BMC Evolutionary Biology, 2013
  • Review of Dengue Hemorrhagic Fever Fatal Cases Seen Among Adults: A Retrospective Study
    Sing-Sin Sam, Sharifah Faridah Syed Omar, Boon-Teong Teoh, Juraina Abd-Jamil, Sazaly AbuBakar
    Plos Neglected Tropical Diseases, 2013
  • Isolation of ancestral sylvatic dengue virus type 1, Malaysia
    Boon-Teong Teoh, Sing-Sin Sam, Juraina Abd-Jamil, Sazaly AbuBakar
    Emerging Infectious Diseases, 2010
  • Molecular identification of adenovirus causing respiratory tract infection in pediatric patients at the University of Malaya Medical Center
    Juraina Abd-Jamil, Boon-Teong Teoh, Eddy H Hassan, Nuruliza Roslan, Sazaly AbuBakar
    BMC Pediatrics, 2010
  • Dengue virus type 2 envelope protein displayed as recombinant phage attachment protein reveals potential cell binding sites
    J. Abd-Jamil, C.-Y. Cheah, S. AbuBakar
    Protein Engineering Design and Selection, 2008
  • Antibody neutralization and viral virulence in recurring dengue virus type 2 outbreaks
    Sook-San Wong, Juraina Abd-Jamil, Sazaly Abubakar
    Viral Immunology, 2007

RECENT SCHOLAR PUBLICATIONS

  • LOW-LEVEL CIRCULATION OF CHIKUNGUNYA VIRUS DURING COVID-19 MOBILITY RESTRICTIONS IN THE KLANG VALLEY, MALAYSIA
    SK Loong, MMS Zulkifli, FS Lim, YZ Lim, P Hassandarvish, KK Tan, ...
    The Southeast Asian Journal of Tropical Medicine and Public Health 57 (3 … , 2026
    2026
  • RESEARCH ARTICLE Decrease in RT-PCR Ct values among SARS-CoV-2 positive samples during the emergence of B. 1.617. 2 (Delta) variant in Malaysia
    N Che-Kamaruddin, BT Teoh, KK Tan, JY Tan, JE Wong, V Tiong, ...
    Tropical Biomedicine 42 (1), 1-9 , 2025
    2025
  • MERS-CoV seroconversion amongst Malaysian Hajj pilgrims returning from the Middle East, 2016–2018: results from the MERCURIAL multiyear prospective cohort study
    J Johari, RD Hontz, BL Pike, T Husain, N Rusli, R Mohd-Zain, V Tiong, ...
    Emerging Microbes & Infections 12 (1), 2208678 , 2023
    2023
    Citations: 3
  • A TaqMan minor groove binder probe-based quantitative reverse transcription polymerase chain reaction for detection and quantification of Chikungunya virus.
    YZ Lim, BT Teoh, SS Sam, NS Azizan, CS Khor, SS Nor'e, J Abd-Jamil, ...
    2023
  • CONTINUOUS INTRODUCTION, DISPERSAL, AND REPLACEMENT OF SARSCOV-2 VARIANTS IN KEDAH, MALAYSIA
    KK Tan, JY Tan, JE Wong, WW Aw, J Abd-Jamil, SS Nor'e, N Yaacob, ...
    International Journal of Infectious Diseases 134, S1 , 2023
    2023
    Citations: 1
  • Early diagnostic indicators of dengue versus other febrile illnesses in Asia and Latin America (IDAMS study): a multicentre, prospective, observational study
    KD Rosenberger, LP Khanh, F Tobian, N Chanpheaktra, V Kumar, ...
    The Lancet Global Health 11 (3), e361-e372 , 2023
    2023
    Citations: 22
  • Effectiveness of dengue awareness calendar on indigenous population: Impact on knowledge, belief and practice
    LP Wong, A Rajandra, J Abd Jamil, S AbuBakar, Y Lin, HY Lee
    Healthcare 11 (5), 637 , 2023
    2023
    Citations: 14
  • Epidemiological serosurvey of chikungunya fever post outbreak at Tanjung Sepat, Malaysia
    CS Khor, BT Teoh, SS Sam, HY Khoo, NS Azizan, AA CheMatSeri, ...
    The Journal of Infection in Developing Countries 17 (01), 118-124 , 2023
    2023
    Citations: 3
  • Development of a TaqMan minor groove binding probe-based quantitative reverse transcription polymerase chain reaction for the detection and quantification of Zika virus.
    KL Chin, BT Teoh, SS Sam, SK Loong, KK Tan, NS Azizan, YK Lim, ...
    2022
    Citations: 1
  • Decrease in RT-PCR Ct values among SARS-CoV-2 positive samples during the emergence of the B. 1.617. 2 (Delta) variant in Malaysia
    N Che-Kamaruddin, B Teoh, K Tan, J Tan, J Wong, V Tiong, J Abd-Jamil, ...
    2022
    Citations: 2
  • Group IV getah virus in Culex mosquitoes, Malaysia
    SS Sam, NA Mohamed-Romai-Noor, BT Teoh, ZR Hamim, HY Ng, ...
    Emerging infectious diseases 28 (2), 475 , 2022
    2022
    Citations: 18
  • Emergence of B. 1.524 (G) SARS-CoV-2 in Malaysia during the third COVID-19 epidemic wave
    KK Tan, JY Tan, JE Wong, BT Teoh, V Tiong, J Abd-Jamil, SS Nor’e, ...
    Scientific reports 11 (1), 22105 , 2021
    2021
    Citations: 25
  • Detecting dengue outbreaks in Malaysia using geospatial techniques
    S Nellis, SK Loong, J Abd-Jamil, R Fauzi, S AbuBakar
    Geospatial Health 16 (2) , 2021
    2021
    Citations: 4
  • Multiyear prospective cohort study to evaluate the risk potential of MERS-CoV infection among Malaysian Hajj pilgrims (MERCURIAL): a study protocol
    J Johari, RD Hontz, BL Pike, T Husain, CK Chong, N Rusli, LH Sulaiman, ...
    BMJ open 11 (8), e050901 , 2021
    2021
    Citations: 3
  • Detection and confirmation of dengue pre‐and postintroduction of dengue NS1‐antigen test at the University Malaya Medical Centre: An observational study
    J Abd‐Jamil, NS Azizan, NAA Che‐Mat‐Seri, CN Yaacob, NI Samsudin, ...
    Journal of Medical Virology 93 (8), 4714-4719 , 2021
    2021
    Citations: 6
  • Multiplex sequencing of SARS-Cov-2 genome directly from clinical samples using the Ion Personal Genome Machine (PGM)
    K Tan, VJ Tiong, T Jia-Yi, J Wong, B Teoh, J Abd-Jamil, J Johari, SS Nor'E, ...
    2021
    Citations: 5
  • A reverse transcription loop-mediated isothermal amplification for broad coverage detection of Asian and African Zika virus lineages
    BT Teoh, KL Chin, NI Samsudin, SK Loong, SS Sam, KK Tan, CS Khor, ...
    BMC infectious diseases 20 (1), 947 , 2020
    2020
    Citations: 7
  • Dengue fever among febrile patients in Taiz City, Yemen during the 2016 war: Clinical manifestations, risk factors, and patients knowledge, attitudes, and practices toward the …
    KAA Alghazali, BT Teoh, SS Sam, J Abd-Jamil, J Johari, WM Atroosh, ...
    One Health 9, 100119 , 2020
    2020
    Citations: 38
  • Research Article Possible Factors Influencing the Seroprevalence of Dengue among Residents of the Forest Fringe Areas of Peninsular Malaysia
    J Abd-Jamil, R Ngui, S Nellis, R Fauzi, ALY Lim, K Chinna, CS Khor, ...
    2020
  • Possible factors influencing the seroprevalence of dengue among residents of the forest fringe areas of Peninsular Malaysia
    J Abd-Jamil, R Ngui, S Nellis, R Fauzi, ALY Lim, K Chinna, CS Khor, ...
    Journal of tropical medicine 2020 (1), 1019238 , 2020
    2020
    Citations: 18

MOST CITED SCHOLAR PUBLICATIONS

  • Review of dengue hemorrhagic fever fatal cases seen among adults: a retrospective study
    SS Sam, SFS Omar, BT Teoh, J Abd-Jamil, S AbuBakar
    PLoS neglected tropical diseases 7 (5), e2194 , 2013
    2013
    Citations: 259
  • Colorimetric detection of dengue by single tube reverse-transcription-loop-mediated isothermal amplification
    YL Lau, MY Lai, BT Teoh, J Abd-Jamil, J Johari, SS Sam, KK Tan, ...
    PloS one 10 (9), e0138694 , 2015
    2015
    Citations: 120
  • Dengue virus type 1 clade replacement in recurring homotypic outbreaks
    BT Teoh, SS Sam, KK Tan, J Johari, MH Shu, MB Danlami, J Abd-Jamil, ...
    BMC evolutionary biology 13 (1), 213 , 2013
    2013
    Citations: 70
  • Molecular identification of adenovirus causing respiratory tract infection in pediatric patients at the University of Malaya Medical Center
    J Abd-Jamil, BT Teoh, EH Hassan, N Roslan, S AbuBakar
    BMC pediatrics 10 (1), 46 , 2010
    2010
    Citations: 66
  • The use of NS1 rapid diagnostic test and qRT-PCR to complement IgM ELISA for improved dengue diagnosis from single specimen
    BT Teoh, SS Sam, KK Tan, J Johari, J Abd-Jamil, PS Hooi, S AbuBakar
    Scientific reports 6 (1), 27663 , 2016
    2016
    Citations: 61
  • Isolation of ancestral sylvatic dengue virus type 1, Malaysia
    BT Teoh, SS Sam, J Abd-Jamil, S AbuBakar
    Emerging infectious diseases 16 (11), 1783 , 2010
    2010
    Citations: 58
  • Dengue outbreak during ongoing civil war, Taiz, Yemen
    KAA Alghazali, BT Teoh, SK Loong, SS Sam, NAA Che-Mat-Seri, ...
    Emerging infectious diseases 25 (7), 1397 , 2019
    2019
    Citations: 39
  • Dengue fever among febrile patients in Taiz City, Yemen during the 2016 war: Clinical manifestations, risk factors, and patients knowledge, attitudes, and practices toward the …
    KAA Alghazali, BT Teoh, SS Sam, J Abd-Jamil, J Johari, WM Atroosh, ...
    One Health 9, 100119 , 2020
    2020
    Citations: 38
  • Seroprevalence of Borrelia burgdorferi among the indigenous people (Orang Asli) of Peninsular Malaysia
    H Hassan
    Journal of infection in developing countries , 2019
    2019
    Citations: 33
  • Antibody neutralization and viral virulence in recurring dengue virus type 2 outbreaks
    SS Wong, J Abd-Jamil, S Abubakar
    Viral immunology 20 (3), 359-368 , 2007
    2007
    Citations: 31
  • Emergence of B. 1.524 (G) SARS-CoV-2 in Malaysia during the third COVID-19 epidemic wave
    KK Tan, JY Tan, JE Wong, BT Teoh, V Tiong, J Abd-Jamil, SS Nor’e, ...
    Scientific reports 11 (1), 22105 , 2021
    2021
    Citations: 25
  • Seroprevalence of Q fever among the indigenous people (Orang Asli) of Peninsular Malaysia
    CS Khor, NF Mohd-Rahim, H Hassan, JR Chandren, SS Nore, J Johari, ...
    Vector-Borne and Zoonotic Diseases 18 (3), 131-137 , 2018
    2018
    Citations: 25
  • Early diagnostic indicators of dengue versus other febrile illnesses in Asia and Latin America (IDAMS study): a multicentre, prospective, observational study
    KD Rosenberger, LP Khanh, F Tobian, N Chanpheaktra, V Kumar, ...
    The Lancet Global Health 11 (3), e361-e372 , 2023
    2023
    Citations: 22
  • A quantitative reverse transcription-polymerase chain reaction for detection of Getah virus
    SS Sam, BT Teoh, CM Chee, NA Mohamed-Romai-Noor, J Abd-Jamil, ...
    Scientific reports 8 (1), 17632 , 2018
    2018
    Citations: 22
  • Disruption of predicted dengue virus type 3 major outbreak cycle coincided with switching of the dominant circulating virus genotype
    KK Tan, NI Zulkifle, J Abd-Jamil, S Sulaiman, CN Yaacob, NS Azizan, ...
    Infection, Genetics and Evolution 54, 271-275 , 2017
    2017
    Citations: 22
  • Emergence of the Asian lineage dengue virus type 3 genotype III in Malaysia
    KK Tan, NI Zulkifle, S Sulaiman, SP Pang, NA NorAmdan, NA MatRahim, ...
    BMC Evolutionary Biology 18 (1), 58 , 2018
    2018
    Citations: 21
  • Dengue death with evidence of hemophagocytic syndrome and dengue virus infection in the bone marrow
    HA Ab-Rahman, PF Wong, H Rahim, J Abd-Jamil, KK Tan, S Sulaiman, ...
    SpringerPlus 4 (1), 665 , 2015
    2015
    Citations: 19
  • Dengue virus type 2 envelope protein displayed as recombinant phage attachment protein reveals potential cell binding sites
    J Abd-Jamil, CY Cheah, S AbuBakar
    Protein Engineering, Design & Selection 21 (10), 605-611 , 2008
    2008
    Citations: 19
  • Group IV getah virus in Culex mosquitoes, Malaysia
    SS Sam, NA Mohamed-Romai-Noor, BT Teoh, ZR Hamim, HY Ng, ...
    Emerging infectious diseases 28 (2), 475 , 2022
    2022
    Citations: 18
  • Possible factors influencing the seroprevalence of dengue among residents of the forest fringe areas of Peninsular Malaysia
    J Abd-Jamil, R Ngui, S Nellis, R Fauzi, ALY Lim, K Chinna, CS Khor, ...
    Journal of tropical medicine 2020 (1), 1019238 , 2020
    2020
    Citations: 18