Sirous Eydivandi

@behbahan.iau.ir

Department of Animal Science, Islamic Azad University, Behbahan Branch, Behbahan, Iran
Islamic Azad University, Behbahan Beranch

Sirous Eydivandi


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https://researchid.co/6639742942

RESEARCH, TEACHING, or OTHER INTERESTS

Biochemistry, Genetics and Molecular Biology, Animal Science and Zoology, Genetics, Agricultural and Biological Sciences
5

Scopus Publications

164

Scholar Citations

7

Scholar h-index

6

Scholar i10-index

Scopus Publications

  • Search for Association between Ovine Wingless-Type MMTV Integration Site Family Member (Wnt10A) Genes with Supernumerary Teat in Ghezel and Romanov Sheep
    Iranian Journal of Applied Animal Science, 2022
  • Genomic scans for selective sweeps through haplotype homozygosity and allelic fixation in 14 indigenous sheep breeds from Middle East and South Asia
    Sirous Eydivandi, Mahmoud Amiri Roudbar, Mohammad Osman Karimi, Goutam Sahana
    Scientific Reports, 2021
    The performance and productivity of livestock have consistently improved by natural and artificial selection over the centuries. Both these selections are expected to leave patterns on the genome and lead to changes in allele frequencies, but natural selection has played the major role among indigenous populations. Detecting selective sweeps in livestock may assist in understanding the processes involved in domestication, genome evolution and discovery of genomic regions associated with economically important traits. We investigated population genetic diversity and selection signals in this study using SNP genotype data of 14 indigenous sheep breeds from Middle East and South Asia, including six breeds from Iran, namely Iranian Balochi, Afshari, Moghani, Qezel, Zel, and Lori-Bakhtiari, three breeds from Afghanistan, namely Afghan Balochi, Arabi, and Gadik, three breeds from India, namely Indian Garole, Changthangi, and Deccani, and two breeds from Bangladesh, namely Bangladeshi Garole and Bangladesh East. The SNP genotype data were generated by the Illumina OvineSNP50 Genotyping BeadChip array. To detect genetic diversity and population structure, we used principal component analysis (PCA), admixture, phylogenetic analyses, and Runs of homozygosity. We applied four complementary statistical tests, FST(fixation index), xp-EHH (cross-population extended haplotype homozygosity), Rsb (extended haplotype homozygosity between-populations), and FLK (the extension of the Lewontin and Krakauer) to detect selective sweeps. Our results not only confirm the previous studies but also provide a suite of novel candidate genes involved in different traits in sheep. On average, FST, xp-EHH, Rsb, and FLK detected 128, 207, 222, and 252 genomic regions as candidates for selective sweeps, respectively. Furthermore, nine overlapping candidate genes were detected by these four tests, especially TNIK, DOCK1, USH2A, and TYW1B which associate with resistance to diseases and climate adaptation. Knowledge of candidate genomic regions in sheep populations may facilitate the identification and potential exploitation of the underlying genes in sheep breeding.
  • A selection signatures study among Middle Eastern and European sheep breeds
    Sirous Eydivandi, Mahmoud Amiri Roudbar, Siavash Salek Ardestani, Mehdi Momen, Goutam Sahana
    Journal of Animal Breeding and Genetics, 2021
    Selection, both natural and artificial, leaves patterns on the genome during domestication of animals and leads to changes in allele frequencies among populations. Detecting genomic regions influenced by selection in livestock may assist in understanding the processes involved in genome evolution and discovering genomic regions related to traits of economic and ecological interests. In the current study, genetic diversity analyses were conducted on 34,206 quality‐filtered SNP positions from 450 individuals in 15 sheep breeds, including six indigenous breeds from the Middle East, namely Iranian Balouchi, Afshari, Moghani, Qezel, Karakas and Norduz, and nine breeds from Europe, namely East Friesian Sheep, Ile de France, Mourerous, Romane, Swiss Mirror, Spaelsau, Suffolk, Comisana and Engadine Red Sheep. The SNP genotype data generated by the Illumina OvineSNP50 Genotyping BeadChip array were used in this analysis. We applied two complementary statistical analyses, FST(fixation index) and xp‐EHH (cross‐population extended haplotype homozygosity), to detect selection signatures in Middle Eastern and European sheep populations. FSTand xp‐EHH detected 629 and 256 genes indicating signatures of selection, respectively. Genomic regions identified using FSTand xp‐EHH contained the CIDEA, HHATL, MGST1, FADS1, RTL1 and DGKG genes, which were reported earlier to influence a number of economic traits. Both FSTand xp‐EHH approaches identified 60 shared genes as the signatures of selection, including four candidate genes (NT5E, ADA2, C8A and C8B) that were enriched for two significant Gene Ontology (GO) terms associated with the adenosine metabolic procedure. Knowledge about the candidate genomic regions under selective pressure in sheep breeds may facilitate identification of the underlying genes and enhance our understanding on these genes role in local adaptation.
  • Genetic diversity in Iranian indigenous sheep vis-à-vis selected exogenous sheep breeds and wild mouflon
    S. Eydivandi, G. Sahana, M. Momen, M.H. Moradi, A.A. Schönherz
    Animal Genetics, 2020
    SummaryThe heterogeneity of climate and different agro‐ecological conditions in Iran have resulted in development of 27 indigenous sheep breeds. Wild Asiatic mouflon (Ovis orientalis) is believed to be the ancestor of Iranian sheep. Evaluation of genetic diversity and population structure within and among domestic breeds has important implications for animal breeding programs and genetic resources management. Based on 50K SNP genotype data, we studied the genetic diversity of five indigenous Iranian sheep breeds: Afshari (n = 37), Moghani (n = 34), Qezel (n = 35), Zel (n = 46) and Lori‐Bakhtiari (n = 46), and Asiatic mouflon (n = 8) sampled from Iran. Furthermore, genetic diversity and the breed admixture of Iranian sheep were assessed on a larger geographic scale using a reference panel comprising: three indigenous Afghan breeds – Arabi (n = 15), Balouchi (n = 15) and Gadik (n = 15); three indigenous breeds from Turkey and Cyprus – Cyprus Fat Tail (n = 30), Karakas (n = 18) and Norduz (n = 20); and three commercial European breeds – Suffolk (n = 19), Comisana (n = 24) and Engadine Red Sheep (n = 24). The results revealed that the investigated breeds are divided into five genetically distinct clusters according to their geographic origin. Afshari was closest to the local mouflon population and showed signs of mouflon admixture. Qezel was identified as a hybrid sheep breed. Much evidence supported the Afghan breeds being identical. Inbreeding values, which were estimated based on ROHs, were highest for Suffolk (FROH = 0.0544) and lowest for Balouchi (FROH = 0.0078). In conclusion, analysis of selected breeds from neighboring countries along with Asiatic mouflon gave a deeper insight into the evolutionary history and origin of Iranian sheep with important implications for future breed management.
  • Phenotypic and genetic analysis of Lori-Bakhtiari lamb's weight at different ages for autosomal and sex-linked genetic effects
    Iranian Journal of Applied Animal Science, 2018

RECENT SCHOLAR PUBLICATIONS

  • Study of the genetic structure of 6 Middle Eastern and European cattle breeds
    S Eydivandi, S Ghanavati
    Breeding and Improvement of Livestock 3 (1), 69-79 , 2024
    2024.0
  • Search for Association between Ovine Wingless-Type MMTV Integration Site Family Member (Wnt10A) Genes with Supernumerary Teat in Ghezel and Romanov Sheep.
    S Eydivandi, S Eghbalsaied, M Momen, E Khajouei, A Javanmard, ...
    Iranian Journal of Applied Animal Science 12 (2) , 2022
    2022.0
    Citations: 1
  • A selection signatures study among Middle Eastern and European sheep breeds
    S Eydivandi, MA Roudbar, SS Ardestani, M Momen, G Sahana
    Journal of Animal Breeding and Genetics 138 (5), 574-588 , 2021
    2021.0
    Citations: 29
  • Genomic scans for selective sweeps through haplotype homozygosity and allelic fixation in 14 indigenous sheep breeds from Middle East and South Asia
    S Eydivandi, MA Roudbar, MO Karimi, G Sahana
    Scientific Reports 11 (1), 2834 , 2021
    2021.0
    Citations: 50
  • Genomic Scans for Selective Sweeps With Four Complementary Statistical Tests on 14 Indigenous Sheep Breeds From Middle East and South Asia
    S Eydivandi, MO Karimi, MA Roudbar, G Sahana
    2020.0
  • Genetic diversity in Iranian indigenous sheep vis‐à‐vis selected exogenous sheep breeds and wild mouflon
    S Eydivandi, G Sahana, M Momen, MH Moradi, AA Schönherz
    Animal Genetics 51 (5), 772-787 , 2020
    2020.0
    Citations: 24
  • Genetic and Phylogenetic Analysis of the Mitochondrial Genome in Khuzestan Buffalo
    S Savar, H Seyed Abadi, C Eidivandi, I Harasi
    Agricultural Biotechnology Journal 11 (3), 175-190 , 2019
    2019.0
  • تجزیه و تحلیل ژنتیکی و فیلوژنتیکی بخشی از ژنوم میتوکندری در گاومیش‌های خوزستان ‎
    ساور, سیدآبادی, عیدی وندی, حرسی, ایمان ‎
    مجله بیوتکنولوژی کشاورزی 11 (3), 175-190 , 2019 ‎
    2019.0
  • Phenotypic and Genetic Analysis of Lori-Bakhtiari Lamb's Weight at Different Ages for Autosomal and Sex-Linked Genetic Effects.
    M Maraveni, M Vatankhah, S Eydivandi
    Iranian Journal of Applied Animal Science 8 (1) , 2018
    2018.0
    Citations: 18
  • Bioinformatics analysis of DGAT1 gene in domestic ruminnants.
    S Eydivandi
    2015.0
  • A comparative study on beef steers rearing in tie stall and free stall systems
    F Moosavinasab, S Eidivandi, O Ghanbari
    Acta Medica Mediterranea 31, 1399-1403 , 2015
    2015.0
    Citations: 1
  • Study of citrullinaemia disorder in Khuzestan Holstein cattle population of Iran
    C Eydivandi, C Amirinia, NE Jomeh-Kashan, M Chamani, J Fayazi, ...
    African journal of biotechnology 11 (10), 2587-2590 , 2012
    2012.0
    Citations: 9
  • Effect of pectinase, cellulase and hemicellulase on performance and digestibility of diets in broilers
    S Eidivandi, A Mahdavi, F Alemi, SA Hosseini, A Mostafa Tehrani, ...
    Veterinary Research & Biological Products 24 (3), 13-22 , 2011
    2011.0
    Citations: 2
  • Identification of BLAD, dumps and CVM deficiency in Khuzestan Holstein cattle population of Iran.
    C Eydivandi, HR Seyedabadi, C Amirinia
    2011.0
    Citations: 16
  • Study of factor XI deficiency in Khuzestan cattle population of Iran
    C Eydivandi, C Amirinia, N EmamJomeh-Kashan, M Chamani, J Fayazi
    African Journal of Biotechnology 10 (4), 718 , 2011
    2011.0
    Citations: 14
  • Monday, January 23, 2012 Room: B308/309
    S Eidivandi, SA Hosseini, AM Tehrani, V Ghasemloo
    Poult. Sci 91, 1 , 0

MOST CITED SCHOLAR PUBLICATIONS

  • Genomic scans for selective sweeps through haplotype homozygosity and allelic fixation in 14 indigenous sheep breeds from Middle East and South Asia
    S Eydivandi, MA Roudbar, MO Karimi, G Sahana
    Scientific Reports 11 (1), 2834 , 2021
    2021.0
    Citations: 50
  • A selection signatures study among Middle Eastern and European sheep breeds
    S Eydivandi, MA Roudbar, SS Ardestani, M Momen, G Sahana
    Journal of Animal Breeding and Genetics 138 (5), 574-588 , 2021
    2021.0
    Citations: 29
  • Genetic diversity in Iranian indigenous sheep vis‐à‐vis selected exogenous sheep breeds and wild mouflon
    S Eydivandi, G Sahana, M Momen, MH Moradi, AA Schönherz
    Animal Genetics 51 (5), 772-787 , 2020
    2020.0
    Citations: 24
  • Phenotypic and Genetic Analysis of Lori-Bakhtiari Lamb's Weight at Different Ages for Autosomal and Sex-Linked Genetic Effects.
    M Maraveni, M Vatankhah, S Eydivandi
    Iranian Journal of Applied Animal Science 8 (1) , 2018
    2018.0
    Citations: 18
  • Identification of BLAD, dumps and CVM deficiency in Khuzestan Holstein cattle population of Iran.
    C Eydivandi, HR Seyedabadi, C Amirinia
    2011.0
    Citations: 16
  • Study of factor XI deficiency in Khuzestan cattle population of Iran
    C Eydivandi, C Amirinia, N EmamJomeh-Kashan, M Chamani, J Fayazi
    African Journal of Biotechnology 10 (4), 718 , 2011
    2011.0
    Citations: 14
  • Study of citrullinaemia disorder in Khuzestan Holstein cattle population of Iran
    C Eydivandi, C Amirinia, NE Jomeh-Kashan, M Chamani, J Fayazi, ...
    African journal of biotechnology 11 (10), 2587-2590 , 2012
    2012.0
    Citations: 9
  • Effect of pectinase, cellulase and hemicellulase on performance and digestibility of diets in broilers
    S Eidivandi, A Mahdavi, F Alemi, SA Hosseini, A Mostafa Tehrani, ...
    Veterinary Research & Biological Products 24 (3), 13-22 , 2011
    2011.0
    Citations: 2
  • Search for Association between Ovine Wingless-Type MMTV Integration Site Family Member (Wnt10A) Genes with Supernumerary Teat in Ghezel and Romanov Sheep.
    S Eydivandi, S Eghbalsaied, M Momen, E Khajouei, A Javanmard, ...
    Iranian Journal of Applied Animal Science 12 (2) , 2022
    2022.0
    Citations: 1
  • A comparative study on beef steers rearing in tie stall and free stall systems
    F Moosavinasab, S Eidivandi, O Ghanbari
    Acta Medica Mediterranea 31, 1399-1403 , 2015
    2015.0
    Citations: 1
  • Study of the genetic structure of 6 Middle Eastern and European cattle breeds
    S Eydivandi, S Ghanavati
    Breeding and Improvement of Livestock 3 (1), 69-79 , 2024
    2024.0
  • Genomic Scans for Selective Sweeps With Four Complementary Statistical Tests on 14 Indigenous Sheep Breeds From Middle East and South Asia
    S Eydivandi, MO Karimi, MA Roudbar, G Sahana
    2020.0
  • Genetic and Phylogenetic Analysis of the Mitochondrial Genome in Khuzestan Buffalo
    S Savar, H Seyed Abadi, C Eidivandi, I Harasi
    Agricultural Biotechnology Journal 11 (3), 175-190 , 2019
    2019.0
  • تجزیه و تحلیل ژنتیکی و فیلوژنتیکی بخشی از ژنوم میتوکندری در گاومیش‌های خوزستان ‎
    ساور, سیدآبادی, عیدی وندی, حرسی, ایمان ‎
    مجله بیوتکنولوژی کشاورزی 11 (3), 175-190 , 2019 ‎
    2019.0
  • Bioinformatics analysis of DGAT1 gene in domestic ruminnants.
    S Eydivandi
    2015.0
  • Monday, January 23, 2012 Room: B308/309
    S Eidivandi, SA Hosseini, AM Tehrani, V Ghasemloo
    Poult. Sci 91, 1 , 0