Ph.D in Chemistry-Supramolecular Chemistry & Nanoscience (2009-2013)
“Functionalized Supramolecular Receptors: Synthesis, Characterization and Applications”
Department of Chemistry, School of Sciences, Gujarat University, Ahmedabad, Gujarat (UGC-JRF/SRF)
M.Sc. in Pharmaceutical/Organic Chemistry (2006-2008)
Department of Pharmaceutical Chemistry, Sardar Patel University, Vidyanagar, Gujarat, India. Awarded
with securing first class (68 %). Six-months dissertation work on “Synthesis of Novel substituted
acetyl Salicylanilide derivatives and their microbial Activity” (M.Sc. dissertation work May-2008).
B.Sc. in Chemistry (2003-2006)
N.V. Patel College of Pure and Applied Sciences, Sardar Patel University, V. V. Nagar, Gujarat,
India Awarded with securing first class (61 %)
Exploring Thiazoline, Thiophane, and Thiazole Advances in Sulphur-Based Heterocyclic Compounds Nandan Chamanlal Pomal, Keyur D. Bhatt, Ageetha Vanaamudan Demystifying the Complexities of Supramolecular Systems Real World Applications, 2025 Sulphur-containing heterocycles, including thiazoline, thiophane, and thiazole, have garnered significant attention in medicinal chemistry due to their diverse biological activities and crucial roles in the biosynthesis of essential compounds. This review highlights the pivotal roles of these sulfur-containing heterocycles' structural diversity and biological significance. The synthesis section delves into the methods and mechanisms behind the formation of these heterocycles. Thiazoline plays essential role in the biosynthesis of thiamine (vitamin B1) and is synthesized in living organisms. Thiophane is a key structural motif in various biologically active natural products, while thiazole is widely prevalent in antimicrobial peptides and antibiotics. The biological evaluation aspect explores the diverse pharmacological activities of these compounds. Thus, the chapter features insights into synthesis and biological activities of these moieties, provides a valuable resource for researchers in medicinal chemistry and chemical biology.
Functionalized Gold Nanoparticles Enable Colorimetric Biosensing of Pesticides for Advanced Applications: Detection of Pesticides Using Functionalized Gold Nanoparticles Keyur D. Bhatt, Nandan C. Pomal, Dhruvansh Patni, Nihal Patel Demystifying the Complexities of Supramolecular Systems Real World Applications, 2025 The growing use of pesticides in agriculture poses significant risks to food safety and environmental health. Traditional detection methods are accurate but require complex instruments and skilled personnel. Biosensing approaches using functionalized gold nanoparticles (AuNPs) have emerged as rapid, cost-effective, and portable alternatives. This mini-review explores the synthesis, surface modification, and characterization of AuNPs, emphasizing their surface plasmon resonance (SPR) properties for colorimetric biosensing. Pesticide exposure induces aggregation of ligand-functionalized AuNPs, leading to visible color changes detectable without advanced equipment. Recent studies demonstrate the successful detection of pesticides such as paraquat, glyphosate, and deltamethrin across diverse matrices. These biosensors offer advantages like visual output, simplicity, and fast response. Despite some limitations, functionalized AuNPs show strong potential for developing efficient biosensing systems, supporting safer agriculture and environmental monitoring.
Multifunctional Calix[4]Pyrrole Derivatives: Optimized Synthesis and a Dual-Action Study Targeting Tuberculosis and Oxidative Stress Nirali Parmar, Keyur Bhatt, Jaymin Parikh, Nihal Patel Polycyclic Aromatic Compounds, 2025 The ongoing challenge of multidrug-resistant Mycobacterium tuberculosis underscores the urgent need for new therapeutic agents that address both tuberculosis (TB) and associated oxidative stress. This study explores the synthesis and bioactivity of six novel calix[4]pyrrole derivatives fused with amino acids, using an optimized HATU and DIPEA-mediated coupling method to enhance yield and stability. These derivatives were subsequently assessed for their antitubercular and antioxidant activities. By incorporating amino acids, particularly aromatic ones, into the calix[4]pyrrole framework, the study aims to investigate their potential as dual-function therapeutic candidates for managing TB and oxidative stress-related complications.
Data Analysis in Bioanalysis for Interpretation of Experimental Data Jaymin Parikh, Keyur Bhatt, Krunal Modi, Jasbir Sangwan, Alexander A. Solovev, Brij Mohan Bioanalytical Techniques Principles and Applications, 2025 This book chapter provides a comprehensive overview of bioanalytical data, beginning with a fundamental introduction to the field. The discourse encompasses qualitative and quantitative analyses, addressing key aspects essential for understanding diverse biological phenomena. Through a series of case studies, the chapter explores the application of analytical techniques to various data types, including ultraviolet-visible spectra, fluorescence-based data, mass spectrometry, and molecular docking. Each case study is meticulously examined to elucidate the nuances of interpretation and the significance of the results in the context of bioanalysis. The integration of these diverse analyses underscores the interdisciplinary nature of bioanalysis, offering readers a well-rounded perspective on the methodologies employed and their practical applications. This chapter could be a significant resource for researchers seeking to comprehend spectroscopic data for biological studies.
Exploring the Potential of Calixarene-Protected Pd Nanoparticles as Effective Catalysts for Coupling Reactions: A Review Letters in Applied Nanobioscience, 2025 The incorporation of metal nanoparticles (MNPs) as catalysts has gained widespread attention recently due to their unique physicochemical properties, high catalytic activity, and selectivity in various chemical reactions. Developing efficient, low-cost, and environmentally friendly methods for synthesizing MNPs has been an active area of research. This article highlights the growing interest in calixarene-enabled metal nanoparticles (MNPs) as catalysts for various chemical reactions due to their exceptional properties, such as high catalytic activity and selectivity. The article also explores the potential applications of MNPs as catalysts in organic reactions, including reduction, oxidation, and C-C coupling reactions. Overall, this article highlights the potential of calixarene-based Pd MNPs as efficient, low-cost, and environmentally friendly catalysts for various chemical reactions and provides a platform for future research in this field.
Microbes and Nanoconjugated Assistants for Sensing and Detecting Pollutants in Wastewater Keyur Bhatt, Jaymin Parikh, Krunal Modi, Brij Mohan Nano Bioremediation for Wastewater Treatment, 2025 Environmental monitoring has seen a revolutionary advancement with the integration of microbes and nano-conjugated assistants. This innovative method dramatically enhances the sensing and detection of pollutants in wastewater by leveraging the synergy between microbial organisms and advanced nanomaterials. Microbes, with their unique metabolic activities, act as biological sensors that respond to the presence of pollutants. Nanoconjugated assistants further enhance this process by providing improved signal transduction and sensitivity. The combination of these elements not only enables real-time monitoring but also increases the selectivity and efficiency of pollutant detection. The use of nanomaterials offers a high surface area for interaction, ensuring optimal sensitivity even at low pollutant concentrations. Additionally, this integrated sensing system extends beyond conventional pollutants, effectively detecting a diverse range of contaminants. The development of this symbiotic relationship between microbes and nanomaterials holds great promise for addressing the growing challenges of water pollution. This chapter explores the methodologies, advancements, and potential applications of microbes and nanoconjugated assistant sensing in wastewater management, presenting a paradigm shift in environmental monitoring and sustainable water resource utilization.
Recent developments on the removal of antibiotics using carbon-based nanocomposites: A mystic approach in nanoscience Novel Applications of Carbon Based Nano Materials, 2022
A Mini-Review on Recent Application of Silver Nanoparticles: Antimicrobial Potency and as Sensor for Antibiotics Nanosistemi Nanomateriali Nanotehnologii, 2022
Design, Synthesis, and Characterization of TEPE-Zn-MOF as a Turn-On Fluorescent Probe for Pb²⁺ Detection K Modi, D Kher, B Dhumale, N Patel, K Bhatt, CN Patel, V Bhatt, ... Journal of Fluorescence, 1-14 , 2026 2026
Exploring Mushroom Extracts as Green Reducing and Stabilizing Agents for Sustainable Synthesis of Silver Nanoparticles M Shah, E Pithawala, K Bhatt, J Shah, H Shah 2026
Functionalized Gold Nanoparticles Enable Colorimetric Biosensing of Pesticides for Advanced Applications: Detection of Pesticides Using Functionalized Gold Nanoparticles KD Bhatt, NC Pomal, D Patni, N Patel Demystifying the Complexities of Supramolecular Systems: Real World … , 2026 2026
Exploring Thiazoline, Thiophane, and Thiazole Advances in Sulphur-Based Heterocyclic Compounds NC Pomal, KD Bhatt, A Vanaamudan Demystifying the Complexities of Supramolecular Systems: Real World … , 2026 2026
Data Analysis in Bioanalysis for Interpretation of Experimental Data KM Jaymin Parikh, Keyur Bhatt Wiley 1 (132), 34 , 2025 2025
Computational choreography: dissecting the dance of hydrogen bonding and π–π stacking in the fluorescence discrimination mechanism of Ciprofloxacin with supramolecular assembly J Parikh, K Bhatt, K Modi, A Desai, N Patel, C Patel, R Bhola Journal of Biomolecular Structure and Dynamics 43 (14), 7442-7453 , 2025 2025 Citations: 1
Demystifying the Complexities of Supramolecular Systems: Real World Applications K Bhatt 10.4018/979-8-3693-2774-6 1, 316 , 2025 2025
Personalized Cancer Treatment with Nanotechnology K Bhatt, N Patel Nanoparticle Delivery in Cancer Care, 321-352 , 2025 2025
with Nanotechnology K Bhatt, N Patel Nanoparticle Delivery in Cancer Care, 321 , 2025 2025
NANOMATERIALS FUNDAMENTALS, SYNTHESIS, CHARACTERIZATION AND APPLICATIONS K Bhatt https://jecpublication.com/index.php/product/nanomaterials-fundamentals … , 2025 2025
MASTERING RESEARCH METHODOLOGY: CONCEPTS, TOOLS, AND BEST PRACTICES K Bhatt https://jecpublication.com/index.php/pro , 2025 2025
Potential of Aegle marmelos (L.) Corrêa extracts in the management of breast cancer: phytochemical profiling and molecular Docking studies N Rami, K Bhatt Pharmacological Research-Natural Products 7, 100218 , 2025 2025 Citations: 1
Empowering Sustainable Futures: The Role of Higher Education in Achieving the SDGs NP Keyur Bhatt Empirical Economics Letters 24 (Special issue), 10 , 2025 2025
Enhancing Mental Health Support in Inclusive Education: Strategies and Outcomes KB Nihal Patel Empirical Economics Letters 24 (Special issue), https://zenodo.org/records … , 2025 2025
Synthesis, Characterization and its Biological Activity of Novel Bis (Biphenylsulfonylacetamido) Oxacalix[4] Arene Derived from Oxacalixarene KB Mansi Panchal Journal of Chemical Health Risks 15 (5), 10 , 2025 2025
Microbes and Nanoconjugated Assistants for Sensing and Detecting Pollutants in Wastewater K Bhatt, J Parikh, K Modi, B Mohan Nano‐Bioremediation for Wastewater Treatment, 203-220 , 2025 2025 Citations: 1
Potential of Aegle marmelos (L.) Corrêa Extracts in the Management of Breast Cancer: Phytochemical Profiling and Molecular Docking Studies KB Nehal Rami Pharmacological Research - Natural Products 12 (https://doi.org/10.1016/j … , 2025 2025
Multifunctional Calix [4] Pyrrole Derivatives: Optimized Synthesis and a Dual-Action Study Targeting Tuberculosis and Oxidative Stress N Parmar, K Bhatt, J Parikh, N Patel Polycyclic Aromatic Compounds, 1-11 , 2025 2025 Citations: 3
Sustainable Biodiesel Production via Transesterification of Bacillus sp.(OQ135194) Lipids: Optimization Strategies R Chaudhary, P Patel, N Chavda, J Parikh, K Bhatt, D Kanani, P Raval 2025
Smart Heterocyclic sensor-Apparatus for metal ions detection Hit Kardani, Keyur Bhatt, Hasit Vaghani, SP IN Patent 434353-001 , 2025 2025
MOST CITED SCHOLAR PUBLICATIONS
Gamma radiation processed polymeric materials for high performance applications: a review AT Naikwadi, BK Sharma, KD Bhatt, PA Mahanwar Frontiers in Chemistry 10, 837111 , 2022 2022 Citations: 280
Highly stable antibacterial silver nanoparticles as selective fluorescent sensor for Fe3+ ions BA Makwana, DJ Vyas, KD Bhatt, VK Jain, YK Agrawal Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 134, 73-80 , 2015 2015 Citations: 98
Functionalized Silver Nanoparticles as Colorimetric and Fluorimetric Sensor for Environmentally Toxic Mercury Ions: An Overview NC Pomal, KD Bhatt, KM Modi, AL Desai, NP Patel, A Kongor, ... Journal of Fluorescence, doi.org/10.1007/s10895-021-02699-z, 1-15 , 2021 2021 Citations: 80
Novel fluorescent silver nanoparticles: sensitive and selective turn off sensor for cadmium ions BA Makwana, DJ Vyas, KD Bhatt, S Darji, VK Jain Applied Nanoscience 6 (4), 555-566 , 2016 2016 Citations: 79
Design optimization of feeding system and solidification simulation for cast iron H Bhatt, R Barot, K Bhatt, H Beravala, J Shah Procedia Technology 14, 357-364 , 2014 2014 Citations: 78
Calix receptor edifice; scrupulous turn off fluorescent sensor for Fe (III), Co (II) and Cu (II) KD Bhatt, HS Gupte, BA Makwana, DJ Vyas, D Maity, VK Jain Journal of fluorescence 22 (6), 1493-1500 , 2012 2012 Citations: 74
Machine-learning based threat-aware system in software defined networks C Song, Y Park, K Golani, Y Kim, K Bhatt, K Goswami 2017 26th international conference on computer communication and networks … , 2017 2017 Citations: 73
Turn-on fluorescence probe for selective detection of Hg (II) by calixpyrrole hydrazide reduced silver nanoparticle: Application to real water sample KD Bhatt, DJ Vyas, BA Makwana, SM Darjee, VK Jain, H Shah Chinese Chemical Letters 27 (5), 731-737 , 2016 2016 Citations: 73
Highly stable water dispersible calix [4] pyrrole octa-hydrazide protected gold nanoparticles as colorimetric and fluorometric chemosensors for selective signaling of Co (II) ions KD Bhatt, DJ Vyas, BA Makwana, SM Darjee, VK Jain Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 121, 94-100 , 2014 2014 Citations: 67
Influence of tool pin profile and welding parameter on tensile strength of magnesium alloy AZ91 during FSW N Patel, KD Bhatt, V Mehta Procedia technology 23, 558-565 , 2016 2016 Citations: 54
Experimental analysis of friction stir welding of dissimilar alloys AA6061 and Mg AZ31 using circular butt joint geometry HK Sharma, K Bhatt, K Shah, U Joshi Procedia Technology 23, 566-572 , 2016 2016 Citations: 53
Selective recognition by novel calix system: ICT based chemosensor for metal ions KD Bhatt, BA Makwana, DJ Vyas, DR Mishra, VK Jain Journal of Luminescence 146, 450-457 , 2014 2014 Citations: 49
Selective sensing of copper (II) and leucine using fluorescent turn on–off mechanism from calix [4] resorcinarene modified gold nanoparticles BA Makwana, DJ Vyas, KD Bhatt, VK Jain Sensors and Actuators B: Chemical 240, 278-287 , 2017 2017 Citations: 39
Turn-off fluorescence probe for the selective determination of pendimethalin using a mechanistic docking model of novel oxacalix [4] arene M Panchal, M Athar, PC Jha, A Kongor, V Mehta, K Bhatt, V Jain RSC advances 6 (58), 53573-53577 , 2016 2016 Citations: 39
Calix protected gold nanobeacon as turn-off fluorescent sensor for phenylalanine DR Mishra, SM Darjee, KD Bhatt, KM Modi, VK Jain Journal of inclusion phenomena and macrocyclic chemistry 82 (3), 425-436 , 2015 2015 Citations: 31
Rationale and design of the PeriOperative ISchemic Evaluation-3 (POISE-3): a randomized controlled trial evaluating tranexamic acid and a strategy to minimize hypotension in … M Marcucci, TW Painter, D Conen, K Leslie, VV Lomivorotov, D Sessler, ... Trials 23 (1), 101 , 2022 2022 Citations: 30
Dual in vitro and in silico analysis of thiacalix [4] arene dinaphthalene sulfonate for the sensing of 4-nitrotoluene and 2, 3-dinitrotoluene K Modi, U Panchal, C Patel, K Bhatt, S Dey, D Mishra, VK Jain New Journal of Chemistry 42 (4), 2682-2691 , 2018 2018 Citations: 28
A switch‐off fluorescence probe towards Pb (II) and cu (II) ions based on a calix [4] pyrrole bearing amino‐quinoline group KD Bhatt, HD Shah, M Panchal Luminescence 32 (8), 1398-1404 , 2017 2017 Citations: 28
A new colorimetric and fluorescent chemosensor based on thiacalix[4]arene for fluoride ions VKJ Savan M. Darjee, Divya R. Mishra, Keyur D. Bhatt, Disha J. Vyas, Krunal ... Tetrahedron Letters 55, 7094-7098 , 2014 2014 Citations: 28
Fault tolerant traffic engineering in software-defined WAN K Golani, K Goswami, K Bhatt, Y Park 2018 IEEE Symposium on Computers and Communications (ISCC), 01205-01210 , 2018 2018 Citations: 27
