Prospects and applications of nanoemulsions in cosmeceuticals Sagar R. Pardeshi, Amol D. Gholap, Nitin K. Sen, Prakash D. Khandagale, Ishlok M. Khadka, Pankaj R. Pardeshi, Deepanjan Datta, Prabhanjan Giram Nanotechnology in Cosmeceuticals Advances Challenges and Future Perspectives, 2025
Advanced Materials for Next-Generation Energy Storage Devices: A Focus on Efficiency and Cost Reduction P. Chandrakala, Anita Sofia Liz, Vijay Mane, Subramania Bala Jeshurun, Gunjan Sharma, Pankaj R. Pardeshi, R. Senthil Kumar E3s Web of Conferences, 2024 The increasing demand for efficient and cost-effective energy storage systems has pushed extensive research into improved materials for next-generation energy storage devices. This study discusses the crucial significance of material advances in boosting the performance and reducing the costs of storage technologies such as batteries and supercapacitors. Conventional energy storage systems face limits in energy density, charge or discharge rates, and scalability, which impede their broad implementation. Advanced materials, including nanomaterials, solid-state electrolytes, and innovative electrode compounds, offer solutions to these difficulties by enhancing energy efficiency, power output, and overall longevity. Additionally, the use of plentiful and low-cost materials, such as sodium-ion and aluminium-based compounds, presents prospects for significant cost savings. This research analyzes current trends, issues in material manufacturing, and future perspectives for energy storage systems, concentrating on balancing efficiency improvements with cost-effectiveness to enable the rising integration of renewable energy sources. The development of these materials is important to creating sustainable, scalable, and economical energy storage systems for the future.
Comparative Analysis of Supercapacitors vs. Batteries Muntather Almusawi, Aasheesh Shukla, Hemalatha S, P. Kavitha, G.M. Gambhire, Pankaj R. Pardeshi, B. Pragathi E3s Web of Conferences, 2024 This paper presents a comparative analysis of supercapacitors and batteries as energy storage technologies, focusing on key performance metrics such as energy storage capacity, power output, efficiency, and charge/discharge cycles. Supercapacitors are known for their rapid charge and discharge capabilities, high power density, and longevity, making them ideal for applications requiring quick bursts of energy. Conversely, batteries, particularly lithium-ion, offer significantly higher energy density, enabling them to store more energy in a compact form factor, but they suffer from longer charging times and limited cycle life. This study highlights the trade-offs between the two technologies, providing insights into their suitability for various applications, from consumer electronics to renewable energy systems. The findings suggest that while supercapacitors excel in scenarios demanding high power and durability, batteries remain the preferred choice for applications requiring higher energy storage capacity. The analysis underscores the importance of selecting the appropriate energy storage solution based on specific application requirements.
Development and optimization of sustained release moxifloxacin hydro-chloride loaded nanoemulsion for ophthalmic drug delivery: A 32 factorial design approach Sagar R. Pardeshi, Harshal A. Mistari, Rakhi S. Jain, Pankaj R. Pardeshi, Rahul L. Rajput, Dhiraj S. Mahajan, Nitin R. Shirsath Micro and Nanosystems, 2021 Background: Moxifloxacin is a BCS class I drug used in the treatment of bacterial conjunctivitis and keratitis. Despite its high water solubility, it possesses limited bioavailability due to anatomical and physiological constraints associated with the eyes, which require multiple administrations to achieve a therapeutic effect. Objective: In order to prolong drug release and to improve antibacterial efficacy for the treatment of bacterial keratitis and conjunctivitis, moxifloxacin-loaded nanoemulsion was developed. Methods: The concentration of oil (oleic acid), a surfactant (tween 80), and a cosurfactant (propylene glycol) were optimized by employing a 3-level 2-factorial design of the experiment for the development of nanoemulsion. The developed nanoemulsion was characterized by particle size distribution, viscosity, refractive index, pH, drug content and release, Transmission Electron Microscopy (TEM), and antibacterial study. The compatibility of the drug with the excipients was accessed by Fourier Transform Infrared Spectroscopy (FTIR). Result: The average globule size was found to be 198.20 nm. The TEM study revealed that the globules were nearly spherical and well-distributed. In vitro drug release profile of the nanoemulsion showed a sustained drug release (60.12% at the end of 6 h) compared to drug solution, with complete drug released within 2 h. The antibacterial effectiveness of the drug-loaded nanoemulsion improved against S. aureus compared with the marketed formulation. Conclusion: The formulated sustained-release nanoemulsion could be a promising alternative to eye drops with improved patient compliance by minimizing dosing frequency with improved antibacterial activity.
