Oyebisi Mistura Azeez

@unilorin.edu.ng

Professor, Department of Veterinary Physiology and Biochemistry, Faculty of Veterinary Medicine
University of Ilorin

Oyebisi Mistura Azeez


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https://researchid.co/omowunmi

RESEARCH, TEACHING, or OTHER INTERESTS

Veterinary, Physiology (medical)
15

Scopus Publications

582

Scholar Citations

14

Scholar h-index

17

Scholar i10-index

Scopus Publications

  • Effect of diferuloylmethane on neutrophil–lymphocyte ratio, cortisol, and testicular damage in male albino rats co-exposed to thermo-psychological stressors during the hot-humid season
    Folashade Helen Olaifa, Faidat Sanusi, Adam Mohammed, Fatima Sanusi, Basiru Afisu, Aishat Omobolanle Olatunji, Abdulhamid Jamila Atata, Esther Kigir, Tope Ebenezer Adeyeye, Moshood Bolaji, Adiru Afolabi Adegboye, Oyebisi Mistura Azeez
    Comparative Clinical Pathology, 2025
  • Effect of heat stress on vital and hematobiochemical parameters of healthy dogs
    Oyebisi Mistura Azeez, Folashade Helen Olaifa, Adakole Sylvanus Adah, Afisu Basiru, Ganiu Jimoh Akorede, Hauwa Moturayo Ambali, Kolawole Yusuf Suleiman, Fatima Sanusi, Mashood Bolaji
    Veterinary World, 2022
    Background and Aim: Heat stress is a major challenge for animals, impairing their welfare and performance. This study aimed to determine the effect of heat stress on the vital and hematobiochemical parameters of healthy dogs. Materials and Methods: The experimental subjects comprised 10 dogs, encompassing seven males and three non-pregnant females between 2 and 3 years of age. Ambient temperature (AT) and relative humidity (RH) were recorded 2 hourly during the day and the temperature humidity index was calculated. Vital parameters [i.e., rectal temperature (RT), respiratory rate, and heart rate (HR)] were assessed and blood was collected from each dog daily for hematobiochemical analysis. Results: The RT (38.5±0.2°C) of dogs exposed to high AT and high RH (HA/HR) conditions was significantly (p<0.05) higher than that of dogs exposed to HA and low RH (LR) conditions (37.2±0.11°C). Under HA/HR conditions, packed cell volume, hemoglobin concentrations, and white blood cell counts were significantly lower than those of the same dogs exposed to HA/LR conditions. Conversely, under HA/HR conditions, the lymphocyte, monocyte, eosinophil, alanine aminotransferase, aspartate aminotransferase, and cortisol values were significantly higher (p<0.05) than the values obtained in dogs exposed to HA/LR conditions. Meanwhile, the alkaline phosphatase, urea, and glucose levels were significantly lower (p<0.05) in dogs exposed to HA/HR conditions. Conclusion: The exposure of healthy dogs to HA/HR conditions induced heat stress, which may have an adverse effect on their immune status, thereby affecting their health and welfare.
  • Cardioprotective effects of extract of Sclerocarya birrea stem bark on doxorubicin induced cardiotoxicity in rats
    Health Biotechnology and Biopharma, 2021
  • Maintenance Impact of Large Dose of Vitamin C on Proinflammatory Cytokines, Insulin, and Electrocardiographic Parameters of Wistar Rats following Partial Pancreatectomy
    Oyebisi Mistura Azeez, Sadudeen Adetayo Amid, Zubair Salman Abdulkadir, Khalid Talha Biobaku
    Journal of Interferon and Cytokine Research, 2021
    We investigated serum tumor necrosis factor alpha (TNF-α) and interleukins (IL-6 and IL-8) in rats undergoing pancreatic wound healing after partial pancreatectomy. In addition, we studied the effects of partial pancreatectomy on the insulin and the electrocardiography (ECG). We proposed that vitamin C (VitC) could have maintenance impact on TNF-α, IL-6, IL-8, insulin, and ECG parameters of pancreatic wound healing of Wistar rats that had partial pancreatectomy surgery, if administered in large dose. Thirty-five male adult Wistar rats (180-250 g) were randomized into 7 groups, with 5 rats in each group. Group 1 was control. Groups 2, 3, and 4 (phase 1) received oral 1,000 mg/kg VitC, while groups 5, 6, and 7 (phase 2) received only water and feed ad libitum postoperatively for 14 days. One-quarter (¼) pancreatectomy was performed in groups 2 and 5, half (½) pancreatectomy was performed in groups 3 and 6, and three-quarter (¾) pancreatectomy was performed in groups 4 and 7. Significant (P < 0.5) decrease in IL-6 was observed in phase 1 when compared with the control. Significant increase in IL-6 was observed when compared with control. Significant increase in IL-8 was observed in phase 1 (groups 2 and 3) and phase 2 when compared with the control. Significant decrease in TNF-α was observed in phase 1 when compared with the control. Significant decrease in TNF-α was observed in phase 2 (groups 6 and 7) when compared with the control. Insulin level decreased and increased insignificantly in phase 2 and phase 1, respectively, when compared with the control. Although atrial fibrillation was recorded in phase 2 (group 7), normal ECG was seen in the control and phase 1 (group 2). Large dose vitC may be helpful in the reduction of proinflammatory cytokines as well as elevation of insulin and normalization of ECG in rats that had undergone partial pancreatectomy.
  • Thirty days oral Aframomum melegueta extract elicited analgesic effect but influenced cytochrome p4501BI, cardiac troponin T, testicular alfa-fetoprotein and other biomarkers in rats
    K. Talha Biobaku, O. Mistura Azeez, S. Adetayo Amid, T. Nnaemeka Asogwa, A. Abubakar Abdullahi, O. Lukman Raji, J. Atata Abdulhamid
    Journal of Ethnopharmacology, 2021
  • Comparative assessment of electrocardiographic parameters of some birds-an essential diagnostic tool in veterinary practice
    Oyebisi Mistura Azeez, Sirajo Garba, Afisu Basiru, Adakole Sylvanus Adah, Folashade Helen Olaifa, Soliu Akanni Ameen, Hauwa Motunrayo Ambali, Moshood Bolaji, Rashidat Bolanle Balogun
    Endothelial Signaling in Vascular Dysfunction and Disease from Bench to Bedside, 2021
  • Comparative assessment of electrocardiographic parameters of some birds in ilorin-an essential diagnostic tool
    Revista Cubana De Investigaciones Biomedicas, 2019
  • Category: Cardiovascular comparative assessment of electrocardiographic parameters of some birds in ilorin
    Revista Cubana De Investigaciones Biomedicas, 2019
  • Oxidative status in rat kidney exposed to petroleum hydrocarbons
    RolandE Akhigbe, ChikodiN Anigbogu, OyebisiM Azeez
    Journal of Natural Science Biology and Medicine, 2013
    Objective: The study investigates the possible role of oxidative stress on renal tissues in association with petroleum hydrocarbon-induced nephrotoxicity. Materials and Methods: Rats of comparable weights were randomly distributed into 10 groups: Control and groups exposed to kerosene, petrol, and diesel via inhalation, contamination by food, and contamination by water. The exposure lasted for eight weeks. Results: Exposure to petroleum hydrocarbon led to significant rise in serum urea and creatinine, and renal tissue malondialdehyde. It also caused significant reduction in urinary urea and creatinine, and reduced glutathione, superoxide dismutase, and catalase activities of renal tissue homogenate. However, serum and urine concentrations of albumin and total protein were comparable in all groups. Conclusion: Results from this study shows that exposure to petroleum hydrocarbon led to renal dysfunction via oxidative stress, increasing lipid peroxidation and reducing the antioxidant defense mechanism.
  • Exposure to petroleum hydrocarbon: Implications in lung lipid peroxidation and antioxidant defense system in rat
    RolandE Akhigbe, ChikodiN Anigbogu, OyebisiM Azeez
    Toxicology International, 2012
    Objective: Various studies have implicated automobile exhausts as risk factors in cardiovascular and pulmonary diseases; however, there is little or no documentation on the role of the main source of the exhausts, petroleum hydrocarbons, on cardiopulmonary pathologies. Thus, we investigated the effect of petroleum hydrocarbons, using various petroleum products, on histomorphology of the lung and the role of lipid peroxidation in it. Materials and Methods: Control rats were not exposed to any of the petroleum products, whereas petrol-exposed, diesel-exposed, and kerosene-exposed rats were exposed to petrol, diesel, and kerosene by inhalation, respectively. Results: Exposure to petroleum hydrocarbons significantly induced lipid peroxidation with a consequent rise in malondialdehyde (MDA), and a decrease in superoxide dismutase (SOD) and catalase (CAT) activities and glutathione (GSH) level. Exposure to petroleum hydrocarbons also caused an alteration in the histomorphology of lung tissues. Conclusion: Our findings imply that exposure to petroleum hydrocarbons by inhalation is a risk factor in the pathophysiology of pulmonary dysfunction. This is associated with oxidative stress.
  • Hematoxicity of amodiaquine in Sprague-Dawley rats
    RE Akhigbe, OM Azeez, WA Saka, AO Akinola
    Toxicology International, 2012
  • Variability in cardiovascular functions and baroflex sensitivity following inhalation of petroleum hydrocarbons
    O.M. Azeez, R.E. Akhigbe, S.F. Ige, W.A. Saka, C.N. Anigbogu
    Journal of Cardiovascular Disease Research, 2012
  • Effects of pyrethroid insecticide exposure on haematological and haemostatic profiles in rats
    W.A. Saka, R.E. Akhigbe, O.M. Azeez, T.R. Babatunde
    Pakistan Journal of Biological Sciences, 2011
  • Immunomodulatory effect of warm water swim-stress in adult female Sprague Dawley rats
    S.F. Ige, R.E. Akhigbe, G.K. Omobowale, O.M. Azeez, F.O. Ajao, W.A. Saka, O.S Oyekunle
    Research Journal of Immunology, 2011
  • Prevalence of haemoglobin variants, ABO and Rhesus blood groups in Ladoke Akintola University of Technology, Ogbomoso, Nigeria
    Akhigbe
    Trends in Medical Research, 2009

RECENT SCHOLAR PUBLICATIONS

  • Effect of diferuloylmethane on neutrophil–lymphocyte ratio, cortisol, and testicular damage in male albino rats co-exposed to thermo-psychological stressors during the hot …
    FH Olaifa, F Sanusi, A Mohammed, F Sanusi, B Afisu, AO Olatunji, ...
    Comparative Clinical Pathology 34 (5), 951-961 , 2025
    2025
  • Melatonin on Vital Parameters, Band Cells, Some Biochemical Parameters and Cortisol Concentration Following Exercise-Induced Stress in Arabian Stallions
    AS ADAH, M ABDULAZEEZ, OM AZEEZ, FH OLAIFA, A BASIRU, ...
    ACTA VETERINARIA , 2024
    2024
    Citations: 1
  • Efek Modulator of Lawsonia inermis, Waltheria indica, Moringa oleifera dan Nigella sativa Terhadap Gambaran Hematologi, Tekanan Darah dan Parameter Elektrokardiografi pada …
    A Abdulfatai, IF Jiddah, AG Jimoh, B Afisu, AO Mistura
    Journal of Applied Veterinary Science & Technology 4 (2) , 2023
    2023
  • Modulatory Effects of Lawsonia inermis, Waltheria indica, Moringa oleifera and Nigella sativa on Haematology, Blood Pressure and Electrocardiographic Parameters of Wistar Rat …
    A Abdulfatai, IF Jiddah, AG Jimoh, B Afisu, AO Mistura
    Journal of Applied Veterinary Science and Technology 4 (2), 2023.80-86 , 2023
    2023
    Citations: 1
  • Vitamin C Protects Against Blood and Thyroid Toxicities Induced by the Chronic Use of Carbamazepine in Rats.
    GJ Akorede, SF Ambali, AO Olatunji, A Aremu, AO Ahmed, A Basiru, ...
    Iranian Journal of Toxicology 17 (2) , 2023
    2023
    Citations: 5
  • Accumulation And Utilization Of Food Reserves In Diapause destined Pallid Emperor Moth, Cirina Forda (Westwood
    MO Oriolowo, O. B, Ande, A. T. & Azeez
    Ife Journal of Science 25 (1), 13-20 , 2023
    2023
    Citations: 1
  • Respiratory activity of the pallid emperor Moth, Cirina forda (Lepidoptera: Saturniidae) during larva and pupa developments
    AMO Oriolowo O.B, Ande A.T
    Journal of Entomology and Zoology Studies 11 (1), 37-42 , 2023
    2023
    Citations: 3
  • Effect of daflon-500 ® , a flavonoid compound on chlorpyriphos-induced oxidative changes in the hypophysis and testes in adult male rats
    AO Olatunji, JO Ayo, MM Suleiman, SF Ambali, M Shittu, GJ Akorede, ...
    Toxicological research 38 (3), 345-353 , 2022
    2022
    Citations: 8
  • Effect of heat stress on vital and hematobiochemical parameters of healthy dogs
    OM Azeez, FH Olaifa, AS Adah, A Basiru, GJ Akorede, HM Ambali, ...
    Veterinary World 15 (3), 722 , 2022
    2022
    Citations: 19
  • Correlation Between Testicular Biometrics and Serum Level of Reproductive Hormones of Crossed Arewa Breed of Stallions in Ilorin, Nigeria
    A Basiru, IO Abdullahi, AS Adakole, AG Jimoh, A Abdulfatai, AO Mistura
    Media Kedokteran Hewan 33 (2), 53-62 , 2022
    2022
    Citations: 2
  • Effect of heat stress on vital and hematobiochemical parameters of healthy dogs, Veterinary World, 15 (3): 722-727
    OM Azeez, FH Olaifa, AS Adah, A Basiru, GJ Akorede, HM Ambali, ...
    Abstract , 2022
    2022
  • Correlation Between Testicular Biometrics and Serum Level of Reproductive Hormones of Arewa Stallions Crossbred in Ilorin, Nigeria
    A Basiru, IO Abdullahi, AS Adakole, AG Jimoh, A Abdulfatai, AO Mistura
    2022
  • Effect of Daytime on the Vital Parameters of Nigerian Local Dogs.
    FH Olaifa, A Bello, AS Adah, A Basiru, F Sanusi, KY Suleiman, OM Azeez, ...
    Savannah Veterinary Journal 5 (1) , 2022
    2022
  • Mitigative potentials of methanol leaf extract of Moringa oleifera on chronic carbamazepine-induced haemo-biochemical and thyrotoxicity in male Wistar rats
    IAKRA Akorede G.J., Ambali, S.F, Olatunji, A.O., Aremu, A. , Basiru, A ...
    Pharmacological Research- - Modern Chinese Medicine, 2667-1425 , 2022
    2022
  • Effects of Daytime on the vital parameters of indigenous dogs
    FH Olaifa, A Bello, AS Adah, A Basiru, F Sanusi, KY Suleiman, OM Azeez, ...
    . Savannah Veterinary journal 5 (1), 28-32 , 2022
    2022
  • Cardioprotective effects of aqueous extract of ripped musa paradisiaca peel in isoproterenol induced myocardial infarction rat model
    KY Suleiman, EO Ajani, KT Biobaku, BS Okediran, MO Azeez, GA Jimoh, ...
    Biomedical Research and Therapy 8 (10), 4634-4648 , 2021
    2021
    Citations: 13
  • Maintenance Impact of Large Dose of Vitamin C on Proinflammatory Cytokines, Insulin, and Electrocardiographic Parameters of Wistar Rats Following Partial Pancreatectomy
    OM Azeez, SA Amid, ZS Abdulkadir, KT Biobaku
    Journal of Interferon & Cytokine Research 41 (5), 187-194 , 2021
    2021
    Citations: 2
  • In vivo bioactivity-guided isolation of antifertility fraction of Waltheria indica Linn. root in male Wistar rats
    B Afisu, A Abdulfatah, AO Mistura, SK Olugboyega, OF Olakitike
    Future Journal of Pharmaceutical Sciences 7 (1), 80 , 2021
    2021
    Citations: 4
  • Thirty days oral Aframomum melegueta extract elicited analgesic effect but influenced cytochrome p4501BI, cardiac troponin T, testicular alfa-fetoprotein and other biomarkers …
    KT Biobaku, OM Azeez, SA Amid, TN Asogwa, AA Abdullahi, OL Raji, ...
    Journal of ethnopharmacology 267, 113493 , 2021
    2021
    Citations: 13
  • Safety evaluation of crude Etanolic Extract of Waltheria Indica Linn. Root In Male Wistar Rats
    SKOOFO Basiru A., Azeez O.M. , Aremu A, Akorede G.J.
    Journal of Veterinary and Biomedical Sciences. 3 (1);112-125. 3 (1), 112-125 , 2021
    2021

MOST CITED SCHOLAR PUBLICATIONS

  • Prevalence of haemoglobin variants, ABO and rhesus blood groups in Ladoke Akintola University of Technology, Ogbomoso, Nigeria.
    RE Akhigbe, SF Ige, AO Afolabi, OM Azeez, GJ Adegunlola, JO Bamidele
    2009
    Citations: 78
  • Oxidative status in rat kidney exposed to petroleum hydrocarbon.
    ACN Azeez O M, Akhigbe R E
    Journal of Natural Science Biology and Medicine, 149-54 , 2013
    2013
    Citations: 60
  • Exposure to petroleum hydrocarbon: Implications in lung lipid peroxidation and antioxidant defense system in rat.
    ACN Azeez O.M, Akhigbe R.E
    Toxicologal International, 306-9 , 2013
    2013
    Citations: 46
  • Effects of pyrethroid insecticide exposure on haematological and haemostatic profiles in rats.
    WA Saka, RE Akhigbe, OM Azeez, TR Babatunde
    Pakistan Journal of Biological Sciences: PJBS 14 (22), 1024-1027 , 2011
    2011
    Citations: 45
  • Malaria, haemoglobin genotypes and ABO blood groups in Ogbomoso, Nigeria.
    RE Akhigbe, SF Ige, GJ Adegunlola, MO Adewumi, MO Azeez
    2011
    Citations: 43
  • Hemorheological Effects of Long-Term Administration of Combined Oral Contraceptive in Rats
    AFOSAO Akhigbe RE, Azeez OM, Ige SF, Oyeyipo IP
    International journal of Pharmacology 4 (5), 403-406 , 2008
    2008
    Citations: 27
  • Varibilityin Cardiovascular Functions and Baroreflex sensitivity following Inhalation of Petroleum Hydrocarbons
    SWA Azeez OM, Akhigbe RE, Anigbogu CN, Ige SF
    Journal of Cardiovascular Disease Research, 99-103 , 2012
    2012
    Citations: 23
  • Comparison of cardio-pulmonary responses to forward and backward walking and running
    AM Adesola, OM Azeez
    African Journal of Biomedical Research 12 (2), 95-100 , 2009
    2009
    Citations: 23
  • Anthelmintic Potency of Carica papaya seeds against Gastro-intestinal Helminths in Red Sokoto goat
    SA Ameen, OM Azeez, YA Baba, LO Raji, A Basiru, KT Biobaku, ...
    Ceylon Journal of Science 47 (2) , 2018
    2018
    Citations: 21
  • Cardiotoxicity induced by inhalation of petroleum products
    SWA Azeez OM, Anigbogu CN, Akhigbe RE
    Journal African Associations Physiological Science 3 (1), 14-17 , 2015
    2015
    Citations: 21
  • Impact of the malaria parasite on reproductive indices of male mice
    Y Raji, OS Akinsomisoye, MO Azeez
    Reproductive medicine and biology 5 (3), 201-209 , 2006
    2006
    Citations: 21
  • Age at menarche and its predicting factors in cities of Ibadan and Ogbomoso of Southwestern Nigeria.
    Y Raji, OA Osonuga, OI Shittu, OS Akinsomisoye, VA Togun, MO Azeez
    2006
    Citations: 21
  • Effect of heat stress on vital and hematobiochemical parameters of healthy dogs
    OM Azeez, FH Olaifa, AS Adah, A Basiru, GJ Akorede, HM Ambali, ...
    Veterinary World 15 (3), 722 , 2022
    2022
    Citations: 19
  • The Ameliorative effects of Moringa oleifera leaf extract on Cardiovascular Functions and Osmotic Fragility of Wistar rats exposed to petrol vapour.
    ABRA OM Azeez, SA Adah, FH Olaifa
    Sokoto Journal of Veterinary Science 15 (2), 36-42 , 2017
    2017
    Citations: 19
  • Cardioprotective effects of aqueous extract of ripped musa paradisiaca peel in isoproterenol induced myocardial infarction rat model
    KY Suleiman, EO Ajani, KT Biobaku, BS Okediran, MO Azeez, GA Jimoh, ...
    Biomedical Research and Therapy 8 (10), 4634-4648 , 2021
    2021
    Citations: 13
  • Thirty days oral Aframomum melegueta extract elicited analgesic effect but influenced cytochrome p4501BI, cardiac troponin T, testicular alfa-fetoprotein and other biomarkers …
    KT Biobaku, OM Azeez, SA Amid, TN Asogwa, AA Abdullahi, OL Raji, ...
    Journal of ethnopharmacology 267, 113493 , 2021
    2021
    Citations: 13
  • Prevalence of haemoglobin variants, ABO, and Rhesus blood groups in Ladoke Akintola University of Technology, Ogbomosho, Nigeria
    RE Akigbe, SF Ige, AO Afolabi, OM Azeez, GJ Adegunlola, JO Bamidele
    Trends in Medical Research 4 (2), 24-29 , 2009
    2009
    Citations: 13
  • Effect of daflon-500 ® , a flavonoid compound on chlorpyriphos-induced oxidative changes in the hypophysis and testes in adult male rats
    AO Olatunji, JO Ayo, MM Suleiman, SF Ambali, M Shittu, GJ Akorede, ...
    Toxicological research 38 (3), 345-353 , 2022
    2022
    Citations: 8
  • Status of Tick Infestation in Ruminant Animals in Ogbomoso Area of Oyo State, Nigeria.
    KTUARAM Ameen SA, Odetokun IA, Ghali-Mohammed LI, Azeez OM, Raji LO
    Journal of Environmental Issue and Agriculture in Developing Countries 6 (23 … , 2014
    2014
    Citations: 8
  • Electrocardiographic parameters in West African Dwarf and Red Sokoto (Maradi) goats.
    OM Azeez, A Basiru, GJ Akorede, SA Adah
    2018
    Citations: 7