Dr. Arvind Negi graduated from SBSPGI, post-graduated from IFTM Moradabad (UPTU), Uttar Pardesh and did his Ph.D. from Himalayan University, Itanagar Arunanchal Pardesh. He has 16 years of teaching and research experience in Pharmacy and has published 50 plus research papers and review articles in different National as well as International journals .Presented 15 papers in different conferences and guided 20 M. Pharm. thesis. He is GATE qualified (2008). He is on editorial board of Journal of Natural Products (Bentham Science). He is member of Board of studies many University for Pharmacy. His interest area in standardization of Herbal drugs and evaluation of plant with ant - diabetic activities and formulations of herbal dosage form.
EDUCATION
B.PHARM,M.PHARM, PhD IN PHARMACY
RESEARCH, TEACHING, or OTHER INTERESTS
Pharmaceutical Science, Pharmacology, Toxicology and Pharmaceutics, Pharmacology, Drug Discovery
DEVELOPMENT AND EVALUATION OF AN AMORPHOUS SOLID DISPERSION-BASED PROBUCOL IMMEDIATE-RELEASE TABLET Vaibhav Adhikari, Mansi Butola, Vikash Jakhmola, Abhijeet Ojha, Arvind Negi Journal of Applied Pharmaceutical Research, 2025 Background: In its crystalline form, probucol has an extremely low bioavailability and is a poor water-soluble drug. The main aim of this study was to enhance the solubility and dissolution rate of probucol by using a solvent evaporation method to develop a solid dispersion that contains polyvinyl pyrrolidone K30 (PVP-K30) and polyethylene glycol 6000 (PEG 6000). Methodology: The solvent evaporation method is considered superior to other techniques for preparing solid dispersions due to its ability to achieve uniform drug distribution at the molecular level. This method ensures homogeneity by dissolving the drug and carrier in a common solvent, reducing the risk of drug recrystallization and enhancing solubility and bioavailability. Result: The drug-to-carrier ratio is the determining factor for dissolution enhancement. The FTIR spectra do not suggest any chemical interaction between PVP-K30 or PEG 6000. The immediate release profiles of both formulations were favourable, with F3 releasing approximately 95.31% of the drug and F6 releasing around 86.77% within 2 hours. This indicates a rapid drug dissolution, which is beneficial for achieving a fast onset of action and enhancing bioavailability. Conclusion: The solid dispersion formulations F3 & F6 successfully transformed crystalline probucol to an amorphous state, enhancing solubility & dissolving rates appropriate for immediate-release tablets.
Antimicrobial potential of Eupatorium adenophorum Spreng Arvind Negi, Amit Semwal Pharmacognosy Journal, 2011 Abstract The antimicrobial activity of Petroleum-ether, Benzene, Chloroform, methanol and aqueous extracts of crude leaves of Eupatorium adenophorum Spreng were tested against the growth of Bacillus subtilis, Bacillus cereus , Staphylococcus aureus , Escherichia coli , Klebsiella aerogenes and Pseudomonas aeruginosa by Paper disk diffusion technique. Nearly all the extracts were found to exhibit moderate to good antibacterial activity against the bacterial pathogens tested and the petroleum ether extract recorded largest zone of inhibition against B. subtilis . The positive results so obtained were compared with that of the reference standard antibiotic ciprofloxacin. Antifungal activity of the above extracts were tested on fungal strains Aspergilus niger , Aspergilus candidus and Candida albicans using Fluconazole as the standard drug. The result shows significant antimicrobial activity of extracts against tested fungi and bacteria.
Antibacterial activity of Diplazium esculentum (Retz.) Sw Semwal Amit, Kaushik Sunil, Bhatt SP, Negi Arvind Pharmacognosy Journal, 2011 The main objective of this research work is to screen various unexploited plants for their antimicrobial activity as these unexploited or pteridophytic plants are being used ethanomedicinally but, very little work has been done on antimicrobial aspects. So, to explore the efficacy of these plants, the following research has been carried out. Aqueous and alcoholic extracts of the plant parts of Diplazium esculentum (Retz.) Sw were tested against the growth of some human and plant pathogenic bacteria like E. coli, Salmonella arizonae, Salmonella typhi, Staphylococcus aureus. Near all the extracts were found effective against these bacteria. The positive results so obtained were compared with that of the Tetracycline reference standard antibiotic. It was found that extracts when mixed in equal proportion with the antibiotic were more effective against bacteria than the antibiotic alone.
RECENT SCHOLAR PUBLICATIONS
Cardio- protective potential of Ocimum sanctum (Tulsi): A Review of Experimental and clinical evidence Arvind Negi, PRAVEEN Rao, Poorva, M.Mubeen, Prateek Panday, Rudhali Lilhare ... Chinese Journal of Health Management 20 (3), 525-535 , 2026 2026
Antihyperglycemic activity of ficus sarmentosa leaf extract on streptozotocin induced diabetic rats AS Arvind Negi, Raj Kumar Mandal, Divya Negi International Journal of Environmental Sciences 11 (12), 5089-5098 , 2025 2025
Revolutionizing diabetes care: the role of artificial intelligence in prevention, diagnosis, and patient care M Kohli, P Pandey, V Jakhmola, S Saha, M Chaudhary, ANM Ansori, ... Journal of Diabetes & Metabolic Disorders 24 (1), 132 , 2025 2025 Citations: 5
DEVELOPMENT AND EVALUATION OF AN AMORPHOUS SOLID DISPERSION-BASED PROBUCOL IMMEDIATE-RELEASE TABLET AN Vaibhav Adhikari1, Mansi Butola1*, Vikash Jakhmola2, Abhijeet Ojha3 JOURNAL OF APPLIED PHARMACEUTICAL RESEARCH | JOAPR 13 (2), 164 – 171 , 2025 2025 Citations: 1
Evaluation of Wound-Healing Activity of Eupatorium Adenophorum Spreng Leaf Extract in Adult WistarRats DN Dr. Arvind Negi1*, Meenakshi Bhatt2, Ankita Pokhriyal2, Babita Negi2 JournalofChemicalHealthRisks 15 (3), 648-657 , 2025 2025
PRINSEPIA UTILIS ROYLE: A COMPEREHENSIVE REVIEW A Negi JETIR.ORG 11 (7), E123-E134 , 2024 2024
LABORATORY APPARTUS TO PREDICTANIMAL TISSUE ACTIVITY A NEGI IN Patent 137,914 , 2023 2023
Pharmacognostical investigation of Adina cordifolia(Roxb.)Brandis, Family Rubiaceae, collected from areas of Haldwani District Nainital. GT • Sweta Negi, Dr. Arvind Negi, Ankita Pokhriyal Journal of Pharmacognosy and Phytochemistry 12 (1), 309-315 , 2023 2023 Citations: 1
ASSESSMENT OF ANTIOXIDANT AND VERMIFUGE ACTIVITY OF SENNA ALATA (L.) ROXB arvind negi International Journal of Novel Research and Development 7 (11), a399-a411 , 2022 2022
Assessment of Antioxidant and Vermifugeactivity of Senna Alata (L.)Roxb Rimi Mondal*, Dr.Arvind Negi IJNRD.ORG 7 (11), A399A411 , 2022 2022
A REVIEW ON PHYTOPHARMACOLOGICAL ACTIVITY OF ALPINIA GALANGA DRAN SADHANA SINGH Indo American Journal of Pharmaceutical Research 12 (08), 499-508 , 2022 2022
PREPARATIVE ISOLATION AND CHARACTERIZATION OF POLYPHENOLS FROM ALPINIAGALANGALINN., GARCINIA INDICACHOISY AND GLYCYRRHIZAGLABRALINN., AND THEIR ROLE AS ANTI-OBESITY … DAN Miss. Sadhna Singh Indo American Journal of Pharmaceutical Research 12 (09), 580-593 , 2022 2022
‘’PRELIMINARY PHYTOCHEMICAL PHARMACOGNOSTICAL STUDY OF FICUS CITRIFOLIA” FAMILY –MORACEAE PDMKM Lalhriatzuali : * Ankita Pokriyal, *Geetika Tripathi,Dr.Arvind Negi International Journal for Research Trends and Innovation 7 (8), 948-954 , 2022 2022
Anti-diabetic herbal composition DA Negi IN Patent E-12/4317/2022/DE L , 2022 2022
BHAMORA (CORNUS CAPITATA): HIMALAYAN WILD EDIBLE PLANT A Negi WORLD JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES 11 (6), , 1168-1176 , 2022 2022
Ethnobotanical and Pharmacological uses of Alternanthera Sessilis V Abhishek Chauhan*, Dr.Arvind negi, Pooja Negi Journal of Emerging Technologies and Innovative Research (JETIR) 9 (5), 632-637 , 2022 2022
A Review on Ethno-botanical uses of Medicinal plant & trees near Tehri Garhwal Himalaya region MJS Vinita Chauhan*, Dr. Arvind Negi, Ms Vandana Pokhariyal, Mr. Subodh Negi Journal of Emerging Technologies and Innovative Research (JETIR) 9 (5), c16-c24 , 2022 2022
A Review on Pharmacological and Phytochemical Spectrum of “Traditional Medicinal plant Adina Cordifolia” Family- Rubiaceae PDMKM Sweta Negi*, Dr. Arvind Negi International Journal of Scientific Development and Research (IJSDR) 7 (4 … , 2022 2022 Citations: 1
MOST CITED SCHOLAR PUBLICATIONS
Formulation and evaluation of an herbal anti-inflammatory gel containing Eupatorium leaves extract A Negi, N Sharma, MF Singh Journal of Pharmacognosy and Phytochemistry 1 (4), 112-117 , 2012 2012 Citations: 39
The study of in vitro antimicrobial activity and phytochemical analysis of some medicinal plants in chamoli garhwal region C Sachin, N Arvind, D Vinesh Pharmacognosy Journal 2 (12), 481-485 , 2010 2010 Citations: 38
Spectrum of pharmacological activities from Bauhinia variegata: a review A Negi, N Sharma, MF Singh Journal of Pharmacy Research 5 (2), 792-797 , 2012 2012 Citations: 36
antibacterial activity of Diplazium esculentum (Retz.) Sw S Amit, K Sunil, N Arvind Pharmacognosy Journal 3 (21), 77-79 , 2011 2011 Citations: 36
A BRIEF REVIEW ON: HAZELNUTS K Dobhal, N Singh, A Semwal, A Negi International Journal of Recent Scientific Research 9 (1), 23680-23684 , 2018 2018 Citations: 33
Determination of total phenolic content of the stem bark of Bauhinia variegata Linn.; an approach to standardization A Negi, N Sharma, R Pant, MF Singh Pharma Research 7 (2), 16-22 , 2012 2012 Citations: 27
Antioxidant Potential and Effect of Extraction Solvent on Total Phenol Content, Flavonoids Content and Tannin Content of Ficus palmata Forssk Arvind Negi*, Pallavi Ghildiyal, Kiran Dobhal International Journal of Pharmaceutical Sciences Review and Research 49 (2 … , 2018 2018 Citations: 20
A Review on Ethnobotany, Phytochemical and Pharmacological Dynamics of Prangos pabularia Lindl. N Sharma, PK Ashok, A Negi, B Lakshmayya Journal of Natural Remedies 13 (2), 68-75 , 2013 2013 Citations: 19
Antimicrobial potential of Eupatorium adenophorum Spreng A Negi, A Semwal Pharmacognosy Journal 2 (18), 61-64 , 2011 2011 Citations: 17
PLANTAGO MAJOR L A CYNOSURE OF MODERN MEDICINE: A REVIEW M Arvind Negi,Manish Mishra World Journal of Pharmaceutical Research 10 (12), 650-675 , 2021 2021 Citations: 11
ACALYPHA INDICA–A BOON TO MANKIND R Mondal, A Negi, M Mishra 2021 Citations: 10
Wound-healing activity of ethanolic and aqueous extracts of Ficus sarmentosa bark A DIMRI, A NEGI, A SEMWAL, N Singh International Journal of Pharmaceutical Research 10 (2) , 2018 2018 Citations: 9
PHARMACOGNOSTICAL STUDIES AND PRELIMINARY PHYTOCHEMICAL INVESTIGATION ON THE BARK OF BAUHINIA VARIEGATA (CAESALPINIACEAEA) AS Arvind Negi*, Pallavi Ghildiyal, Jyotsana Suyal, Kiran Dobhal International Journal of Research in AYUSH and Pharmaceutical Sciences 1 (4 … , 2017 2017 Citations: 9
Pharmacognostical Studies on the Leaves of Eupatorium adenophorum Spreng. A Negi, A Upadhyay, A Semwal, AK Wahi Pharmacognosy Journal 2 (15), 1-7 , 2010 2010 Citations: 8
Revolutionizing diabetes care: the role of artificial intelligence in prevention, diagnosis, and patient care M Kohli, P Pandey, V Jakhmola, S Saha, M Chaudhary, ANM Ansori, ... Journal of Diabetes & Metabolic Disorders 24 (1), 132 , 2025 2025 Citations: 5
Standardization and preliminary phytochemical screening of Ficus Palmata Forssk stem barks ANA Rawat Journal of Pharmaceutical and Biological Sciences 5 (1), 15-20 , 2017 2017 Citations: 5
A REVIEW ON FAST DISSOLVING TABLETS AV Jyoti Saxena1 *, Digvijay Singh2 , Amrita Bisht1 , Arvind Negi1 Journal of Medical P’ceutical and Allied Sciences 10 (1004), 2658-2663 , 2021 2021 Citations: 3
Simultaneous UV Spectrophotometric Valuation of Isotretinoin & their Promoted Drug DAN Kiran Dobhal*, Dr. Deepak Nanda International Journal of Pharmaceutical Sciences Review and Research 49 (1 … , 2018 2018 Citations: 3
DEVELOPMENT AND EVALUATION OF AN AMORPHOUS SOLID DISPERSION-BASED PROBUCOL IMMEDIATE-RELEASE TABLET AN Vaibhav Adhikari1, Mansi Butola1*, Vikash Jakhmola2, Abhijeet Ojha3 JOURNAL OF APPLIED PHARMACEUTICAL RESEARCH | JOAPR 13 (2), 164 – 171 , 2025 2025 Citations: 1
Pharmacognostical investigation of Adina cordifolia(Roxb.)Brandis, Family Rubiaceae, collected from areas of Haldwani District Nainital. GT • Sweta Negi, Dr. Arvind Negi, Ankita Pokhriyal Journal of Pharmacognosy and Phytochemistry 12 (1), 309-315 , 2023 2023 Citations: 1
