Istanbul University, Medical Faculty
Meram University, Pediatric Cardiology
RESEARCH, TEACHING, or OTHER INTERESTS
Cardiology and Cardiovascular Medicine, Pediatrics, Perinatology and Child Health
103
Scopus Publications
Scopus Publications
Paediatric cardiac tamponade requiring pericardiocentesis: aetiology and age distribution of 252 patients in a tertiary single-centre cohort Münevver Tugba Temel, Osman Baspinar Cardiology in the Young, 2025 Objective: Cardiac tamponade is a rare but life-threatening condition in children, typically requiring urgent percutaneous pericardiocentesis. Despite its clinical importance, comprehensive data on paediatric cardiac tamponade are limited. Methods: We retrospectively reviewed 251 paediatric patients (0–18 years) with cardiac tamponade who underwent emergency percutaneous pericardiocentesis to evaluate the aetiological spectrum, age distribution, and associated clinical factors between November 2003 and May 2025. Diagnosis was based on echocardiographic criteria indicating haemodynamic compromise. Patients were categorised by age group, underlying aetiology, and recent history of cardiac intervention. Results: Structural heart diseases were the leading cause of cardiac tamponade (51.6%), particularly in neonates and infants. Pericardiocentesis was most frequently performed in children aged 6–12 years (28.2%). Cardiomyopathies were more prevalent in older age groups. Infectious causes were the second most common aetiology (11.5%). Cardiac Tamponade occurred more frequently following cardiac surgery (12.3%) than after catheter-based interventions. Iatrogenic tamponade was identified in six patients, most commonly during high-risk transcatheter procedures. Genetic syndromes were present in 30 patients, with Down syndrome being the most common. Conclusions: To the best of our knowledge, this study represents the largest single-centre cohort of paediatric cardiac tamponade requiring pericardiocentesis. Cardiac causes, particularly structural heart diseases, represent the most common aetiology across all age groups; therefore, these patients should be promptly evaluated for cardiac tamponade when presenting with relevant symptoms.
A Very Rare Cause of Cardiomyopathy in a Child: Peripartum Cardiomyopathy Osman Başpınar, Serkan Coşkun Genel Tip Dergisi, 2025 Background: Peripartum cardiomyopathy (PCMP) is characterized by severe systolic dysfunction of the heart, manifesting with signs and symptoms of heart failure in the last month of pregnancy or within the first five months postpartum in women with no previously known heart disease. Methods: A childhood-age pregnancy mother who presented to our emergency department at 3 months postpartum with complaints of dyspnea, orthopnea, edema, and palpitations. Following the diagnosis of PCMP, standard cardiomyopathy treatment was initiated alongside bromocriptine therapy. However, during follow-up, the patient died due to heart failure. PCMP, which is rare even in adult patients, can also occur in the pediatric age group. The using bromocriptine, which pediatric cardiologists may be less familiar with, in addition to standard heart failure therapy is needed to cure it, but the nature of the disease could be very severe.
Evaluation of the reduction of radiation dose received by pediatric patients in new-generation biplane angiocardiography: Randomized controlled study Osman Başpınar, Mehmet Kervancıoğlu, Metin Kılınç, Derya Aydın Şahin, Münevver Tuğba Temel Heliyon, 2024 ObjectiveWe aimed to evaluate the safety and efficacy of radiation dose reduction with a new-generation biplane angiocardiography system in patients undergoing transcatheter isolated patent ductus arteriosus (PDA) closure.Materials and methodsFifty pediatric patients who underwent transcatheter PDA closure were randomly divided into two groups as normal radiation dose and low dose. Patients who required additional procedures other than PDA closure were excluded. PDA closure was performed according to the angiographic measurement of the defect. After the procedure, age, weight, sex, PDA measurements, and radiation measurements such as dose-area product (DAP, Gy.cm2) and air kerma (AK, mGy) were compared between the groups.ResultsThere was no statistically significant difference between the groups in age, sex, weight, PDA diameter, PDA type, device used, and device diameter (p > 0.05). While there was no statistically significant difference between the groups in terms of cine recording, number of recorded images, and fluoroscopy time (p > 0.05), there was a statistically significant difference between the total DAP, cine and fluoroscopy DAP, total AK, frontal and lateral tube AK, and DAP/kg (mGy.m2/kg) measurements (p < 0.05).ConclusionTranscatheter PDA closure with a low radiation dose is as effective as that with a normal radiation dose. The radiation dose received by the patient during the procedure was significantly reduced. With the vision provided by this study, it seems possible to work with a low radiation dose in other groups of patients.
One-Year Follow-Up Results of MIS-C Patients with Coronary Artery Involvement: A Multi-center Study Ali Baykan, Yunus Emre Kum, Murat Muhtar Yılmazer, Celal Varan, Kahraman Yakut, Ahmet Sert, Funda Öztunç, Mehmet Öncül, Duygu Uç, Osman Başpınar, Özge Pamukçu, Mehmet Murat, İbrahim Cansaran Tanıdır, Gülsüm Alkan, Nujin Uluğ Murt, Alper Akın, Cemşit Karakurt, Derya Aydın Şahin, Alper Doğan, Derya Duman, Erkut Öztürk, Yusuf İskender Coşkun, Mehmet Türe, Münevver Tuğba Temel, Özlem Elkıran Pediatric Cardiology, 2024
Piccolo in transcatheter PDA closure multi-centre study from premature to adolescent children Osman Baspinar, Nazmi Narin, Ali Baykan, Kaan Yildiz, Ozge Pamukcu, Abdullah Ozyurt, Mehmet Kervancioglu, Yunus Emre Kum, Munevver Tugba Temel, Alper Dogan, Sedat Bagli, Tulay Demircan, Derya Aydin Sahin, Ferhan Elmali, Cem Karadeniz Cardiology in the Young, 2024 In this multi-centre study, the mid- to long-term efficacy and safety of the Amplatzer Piccolo Occluder in patent ductus arteriosus closure in premature and term infants as well as children were discussed. Methods. Between 2016 and 2021, 645 patients, 152 of whom were less than 1 month old, underwent ductus closure with the Piccolo device from five different centres in Turkey. The median age of the patients was 2.2 years, and the mean narrowest point of duct diameter was 1.8 mm. Sixty-two patients weighed ≤ 1.5 kg, 90 patients 1.5–3 kg, and the mean follow-up was 20.4 months. In 396, the duct was closed by the retrograde route. Ductal anatomy was Type A in 285, C in 72, E in 171, and F in 64 patients. Fluoroscopy duration was 6.2 min. The procedure success rate was 99.1%. Device embolisation occurred in 13 patients (2%), and 11 were retrieved with a snare. Cardiac perforation and death developed in one premature baby. The left pulmonary artery and the descending aorta stenosis were observed in 3 (0.4%) and in 5 patients (0.5%). Results. Piccolo device is safe and effective in closing ductus in all age groups. It has low profile for use in premature and newborn babies, a small embolisation risk, and a low residual shunt rate after closure. Conclusion. The Piccolo device can be considered as close an ideal occluder. The lower profile, smaller delivery catheter size, and symmetry of this device allow for a venous or arterial approach.
Piccolo in transcatheter PDA closure multicenter study from premature to adolescent children - CORRIGENDUM Osman Baspinar, Nazmi Narin, Ali Baykan, Kaan Yildiz, Ozge Pamukcu, Abdullah Ozyurt, Mehmet Kervancioglu, Yunus Emre Kum, Munevver Tugba Temel, Alper Dogan, Sedat Bagli, Tulay Demircan, Derya Aydin Sahin, Ferhan Elmali, Cem Karadeniz Cardiology in the Young, 2024 1Pediatric Cardiology, Gaziantep University Medical Faculty, Gaziantep, Turkey; 2Pediatric Cardiology, Izmir Katip Celebi University Medical Faculty, Izmir, Turkey; 3Pediatric Cardiology, Erciyes University Medical Faculty, Kayseri, Turkey; 4Pediatric Cardiology, Tepecik Training and Research Hospital Clinics, Izmir, Turkey; 5Pediatric Cardiology, Mersin Women’s and Children’s Hospital, Mersin, Turkey and 6Biostatistics Department. Izmir Katip Celebi University, Izmir, Turkey
A Global Perspective on PDA Management in the Extremely Premature: Shifting Trend Toward Transcatheter Closure Shyam Sathanandam, Patrick McNamara, Carlos Pedra, Katsuaki Toyoshima, Sophie Malekzadeh-Milani, Juliana Patkai, Osman Baspinar, Hasan Sinan Uslu, Worakan Promphan, Meera Khorana, Jieh-Neng Wang, Yung-Chieh Lin, Takanari Fujii, Gur Mainzer, David Salazar-Lizárraga, Horacio Márquez-Gonzalez, Himanshu Popat, Jonathan Mervis, Neoh Siew Hong, Mazeni Alwi, Ratthapon Wonwandee, Dietmar Schranz, Georgiev Stanimir, Ranjit Philip, Frank Ing Journal of the Society for Cardiovascular Angiography and Interventions, 2023 Patent ductus arteriosus (PDA) is a frequently encountered defect in infants born extremely premature (≤26 weeks' gestation). Historically, closure of the PDA was performed using cyclooxygenase inhibitor medications or by surgical ligations. However, the benefits of PDA closure using these therapies have never been demonstrated, albeit studies have previously not focused on the extremely premature infants. Therefore, there was a worldwide trend toward conservative management of the PDA. With improved survival of extremely premature infants, comorbidities associated with the PDA has increased, resulting in finding alternate treatments such as transcatheter patent ductus arteriosus closure (TCPC) for this population. Currently, there is a renewed interest toward selective treatment of the PDA in this high-risk cohort of small infants. This Comprehensive Review article inspects the globally changing trends in the management of the PDA in premature infants, with a special focus on the rising adoption of TCPC. Moreover, this article compiles data from several neonatal networks worldwide to help understand the problem at hand. Understanding the current management of premature infants and their outcomes is fundamentally essential if pediatric cardiologists are to offer TCPC as a viable therapeutic option for this population. This article aims to serve as a guide for pediatric cardiologists on this topic by compiling the results on landmark clinical trials on PDA management and the controversies that arise from these trials. Comparative outcomes from several countries are presented, including interpretations and opinions of the data from experts globally. This is a step toward coming to a global consensus in PDA management in premature infants.
Unknown origin of acute myocardial infarction and lifesaving percutaneous coronary intervention in a 10-year-old girl Münevver Tugba Temel, Gökhan Altunbaş, Osman Başpınar Annals of Pediatric Cardiology, 2022 Myocardial infarction is extremely rare in children. However, chest pain suspected to be cardiac in origin by the parents is a very common presenting symptom in pediatric emergency services. In this case, an electrocardiogram is very important in the differential diagnosis of cardiogenic complaints and should be carefully considered.
Comparison of transcatheter atrial septal defect closure between children weighing less than 15 kg and children weighing 15 to 20 kg Iranian Heart Journal, 2021
Cytokine gene polymorphisms in childhood dilated Cardiomyopathy: Interferon- gamma, tumor necrosis factor-alpha and transforming growth factor - Beta 1 genes are associated with the disease in Turkish patients Iranian Journal of Pediatrics, 2013
C-reactive protein, Interleukin-6, Interleukin-8, tumor necrosis factor-alpha and hematological guidelines in the diagnosis of neonatal meningitis: A case control study (Neurology Psychiatry and Brain Research (2006) 13, (195-200)) Neurology Psychiatry and Brain Research, 2008
Off-pump pulmonary valve implantation Hasim Ustunsoy, Mehmet Adnan Celkan, Oktay Burma, Hakkı Kazaz, Osman Baspinar Journal of Cardiac Surgery, 2008
C-reactive protein, interleukin-6, interleukin-8, tumor necrosis factor-alpha and hematologic parameters in the diagnosis of neonatal meningitis: A case control study Neurology Psychiatry and Brain Research, 2006
Pulmonary arterial pressure in children with croup syndrome Bülent Oran, Gülsün Ekici, İsmail Reisli, Hamdi Arbağ, Osman Başpınar, Tamer Baysal, Mustafa Doğan, Derya Çimen, Sevim Karaaslan American Journal of Otolaryngology Head and Neck Medicine and Surgery, 2006
Repeated cutdown intervention in cutis marmorata telengiectatica [5] Indian Pediatrics, 2006
A giant left coronary artery to right ventricular fistula: Echocardiographic and postmortem study in a newborn Gazzetta Medica Italiana Archivio Per Le Scienze Mediche, 2006
A rare cause of anemia and thrombocytopenia in a newborn: Congenital malaria Turkish Journal of Pediatrics, 2006