SHANKUL KUMAR

@gnsu.ac

ASSISTANT PROFESSOR, NARAYAN INSTITUTE OF PHARMACY
GOPAL NARAYAN SINGH UNIVERSITY

SHANKUL KUMAR


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https://researchid.co/shankul_kumar

EDUCATION

M.Pharm

RESEARCH, TEACHING, or OTHER INTERESTS

Pharmacy
8

Scopus Publications

367

Scholar Citations

9

Scholar h-index

9

Scholar i10-index

Scopus Publications

  • Analytical and bioactivity-based evaluation of Callistemon citrinus: HPTLC fingerprinting, marker quantification, and antioxidant potential of Hydroalcoholic extracts
    Shankul kumar, Vedant Kumar Prajapati, Shashi Ranjan Singh, Utkarsh Kumar, Sumitra Nain
    Journal of Chromatography B Analytical Technologies in the Biomedical and Life Sciences, 2026
  • Targeting Relapsed Multiple Myeloma with Elranatamab: A Bispecific Antibody Approach
    Shivam Kumar, Arvind Kumar Patel, Dharmendra Kumar, Vikash Kumar, Shankul Kumar
    Cardiovascular and Hematological Agents in Medicinal Chemistry, 2026
    Elranatamab, an IgG2 bispecific antibody targeting B-cell maturation antigen (BCMA) and CD3 on T cells, is a promising therapeutic option for relapsed or refractory multiple myeloma (RRMM), a hematologic malignancy with limited therapeutic options to date. Elranatamab represents a therapeutic breakthrough in the management of patients with RRMM. Bispecific antibodies targeting cytotoxic immune effector cells (including T cells) and malignant plasma cells have demonstrated a high response rate, especially in patients with penta-refractory disease. Elranatamab activates T cells, which mount a targeted and deadly attack on myeloma cells, leading to a more targeted treatment of the disease. Clinical trials showed encouraging efficacy in heavily pretreated patients, with impressive responses and an acceptable safety profile, including manageable cytokine release syndrome (CRS) and other immune-related adverse effects. Despite these recent advances that have accelerated progress, multiple myeloma remains an incurable disease, and patients often relapse with resistance to available treatments. With the evolving treatment landscape for multiple myeloma, informed by recent clinical trial data and new combination regimens, these drugs may play a crucial role in overcoming drug resistance and improving long-term patient survival.
  • Extraction and Characterization Techniques for Phenolic Compounds from Medicinal Plants
    Shankul Kumar, Vedant Kumar Prajapati, Arvind Kumar Patel, Shashi Ranjan Singh, Sumitra Nain
    Phenolic Compounds from Medicinal Plants Pharmaceutical and Health Benefts, 2026
    Phenolic compounds are widely present in medicinal plants that are responsible for their medicinal properties. The various extraction and characterization techniques employed to isolate and characterize phenolic compounds from medicinal plants are discussed in this chapter. Traditional methods of extraction, such as hydrodistillation, Soxhlet extraction, and maceration, are discussed, as well as newer methods, including ultrasound-assisted extraction, supercritical fluid extraction, and microwave-assisted extraction. Spectroscopic methods, such as UV–Visible, Fourier transform infrared (FTIR), and nuclear magnetic resonance (NMR) spectroscopy, as well as chromatographic methods like high-performance liquid chromatography (HPLC) and gas chromatography–mass spectrometry (GC–MS), also fall under the umbrella of characterization methods. Supported by a robust framework for the isolation and characterization of phenolic compounds from medicinal plants, this detailed analysis enables researchers and practitioners to utilize these compounds effectively in pharmaceuticals, nutraceuticals, and other health products.
  • Alkaloids in Cardiovascular Health and Disease Management
    Shankul Kumar, Vedant Kumar Prajapati, Arvind Kumar Patel, Shashi Ranjan Singh, Sumitra Nain
    Alkaloids from Medicinal Plants and their Transformative Applications, 2026
    Alkaloids are significant organic nitrogenous molecules that represent a wealth of information for medication development. Cardiovascular illnesses include congestive heart failure, hypertension, angina pectoris, atherosclerosis, cerebral and peripheral vascular disease, venous insufficiency, and arrhythmia. High mortality and morbidity are related to cardiovascular illnesses linked to hypertension and hyperlipidemia. The most recent and accessible data on alkaloids and their revolutionary role in cardiovascular health and illness prevention were gathered from several sources (PubMed, ScienceDirect, Google Scholar, and Springer Link). This chapter highlights the molecular mechanisms of action of these secondary metabolites, cardiovascular biomarkers, the clinical relevance of cardiovascular biomarkers, and a critical review of the use of naturally occurring alkaloids in treating cardiovascular illness and maintaining cardiovascular health.
  • Anti-Obesity Activity of Phenolic Compounds
    Sumitra Nain, Arvind Kumar Patel, Omsatyam, Shankul Kumar, Vinod Kumar Singh, Vedant Kumar Prajapati
    Phenolic Compounds from Medicinal Plants Pharmaceutical and Health Benefts, 2026
    The potential anti-obesity properties of phenolic compounds, a diverse group of bioactive compounds commonly found in plant-based foods, have garnered considerable attention. The functions of particular phenolic compounds, including cinnamic acid, quercetin, apigenin, catechins, naringenin, and daidzein, in preventing obesity through different pathways are studied in this chapter. Apigenin and kaempferol have been shown in vitro to decrease fat accumulation in human adipocytes produced from mesenchymal stem cells. By altering the expression of genes linked to triglyceride buildup and adipogenesis, promoting lipolysis, and, in certain situations, preventing lipogenesis, these phenolic compounds lower the triglyceride level of adult adipocytes. Several plants contain polyphenols, which have been demonstrated in animal models to reduce fat storage, block fatty acid production, and promote β-oxidation. Activating the sirtuin 1 and AMPK pathways, resveratrol, another well-researched polyphenol, improves energy metabolism and lowers obesity. In animal research, quercetin has shown promise in lowering body weight increase and increasing insulin sensitivity. There are several obstacles to overcome before the anti-obesity properties of phenolic compounds can be applied to humans, as observed in laboratory and animal models. Inconsistent clinical results are caused by variations in doses, bioavailability, study methods, and individual characteristics, including age, gender, and genetics. Understanding the effectiveness of phenolics is further complicated by the intricate relationships they have with other dietary components and the way the gut flora metabolizes them. To determine uniform dosage schedules, evaluate any adverse effects, and validate the therapeutic potential of these substances in the treatment of obesity, more carefully planned, extended clinical trials are required.
  • IoT-Enabled healthcare ecosystems: innovations in remote monitoring, patient outcomes, and digital transformation
    Shankul Kumar, Vedant Kumar Prajapati, Shashi Ranjan Singh, Arvind Kumar Patel, Pushpraj Singh, Manish Singh
    Informatics for Health and Social Care, 2026
    The monitoring, diagnosis, and treatment of patients has been completely transformed by the Internet of Things (IoT) in healthcare, especially in underprivileged and distant locations. IoT-enabled remote patient monitoring (RPM) makes it possible to gather and transmit health data like heart rate, glucose levels, and blood pressure in real-time, facilitating proactive and individualized care. IoT-enabled smart wearable devices like smartwatches, ECG patches, and fitness bands track physical activity and health parameters provide real-time data to clinicians via mobile apps or cloud servers and empower patients with self-monitoring tools. IoT-enabled RFID tags to locate critical medical equipment (e.g. ventilators, infusion pumps) enhances operational efficiency and reduces loss or theft and assists in hospital inventory and supply chain management. IoT devices facilitate real-time consultation with physicians using health data from patients and bridges the healthcare gap in rural and underserved areas. With a focus on RPM systems, Smart Wearables and RFID tags this chapter examines the architecture, technology, uses, and advantages of IoT in healthcare. The difficulties with interoperability, system integration, security, and data privacy are also covered. IoT has the revolutionary potential to improve healthcare outcomes, lower readmission rates to hospitals, and improve the quality of life for patients with chronic illnesses, as demonstrated by case studies and recent advances.
  • Systematic pharmacognostical, phytochemical and pharmacological review on an ethno medicinal plant, Basella alba L
    Shankul Kumar, A. Prasad, S. Iyer, S. K. Vaidya
    Journal of Pharmacognosy and Phytotherapy, 2013
    The ethno medicinal plant Basella alba belongs to the family Basellaceae, and commonly known as malabar spinach, indian spinach, ceylon spinach and vine spinach. Although it has been reported in ancient systems of medicine, it did not gain much importance and has always remained controversial. It has been found to be a good source of calcium, iron, vitamin A and vitamin C. In the Indian system of medicine, the plant has immense potential in androgenic activity, antiulcer activity, antioxidant, cytotoxic and antibacterial activity, anti-inflammatory activity, central nervous system (CNS) depressant activity, nephroprotective and wound healing properties etc. The present is therefore, an effort to give a detailed survey of literature on pharmacognostical, phytochemical, ethnopharmacology as well as the pharmacological activities of the plant. Key words: Nephroprotective, cytotoxic, androgenic, antiulcer activity, antioxidant, spinach.
  • Pharmacognostical investigation on wheat grass
    International Journal of Pharma and Bio Sciences, 2010

RECENT SCHOLAR PUBLICATIONS

  • Analytical and bioactivity-based evaluation of Callistemon citrinus: HPTLC fingerprinting, marker quantification, and antioxidant potential of Hydroalcoholic extracts
    VK Prajapati, SR Singh, U Kumar, S Nain
    Journal of Chromatography B, 125065 , 2026
    2026
  • Alkaloids From Medicinal Plants and Their Transformative Applications
    RK Bachheti, A Bachheti, A Husen
    CRC Press , 2026
    2026
  • IoT-Enabled healthcare ecosystems: innovations in remote monitoring, patient outcomes, and digital transformation
    S Kumar, VK Prajapati, SR Singh, AK Patel, P Singh, M Singh
    Informatics for Health and Social Care, 1-24 , 2026
    2026
  • Phytochemical screening, investigations & antimicrobial activity on the various extracts obtained from the aerial parts of Alternanthera sessilis (Joyweed) and Crepidium …
    V Nigam, S Kumar, S Dubey, K Agarwal, S Chaurasia
    IP International Journal of Comprehensive and Advanced Pharmacology 8 (4 … , 2023
    2023
    Citations: 1
  • Two porous plugs better than one?
    A Gupta, S Kumar, V Kumar, A Prasad, S Roy, RK Singh, A Paul, ...
    Steel Times International 44 (5), 35-40 , 2020
    2020
  • INDUSTRY 4.0: complex, disruptive, but inevitable. Management and Production Engineering Review, 11 (1), 43–51
    S Kumar, M Suhaib, M Asjad
    2020
    Citations: 5
  • Research Scholars' Perceptions on Factors Influencing Stress: A Triangular (Family-Work-Research) Horizon
    MSVS Kumar, AVVS Prasad, PV Kumar
    UGC Approved: Serial No: 46802, 107 , 2018
    2018
  • PHYTOCHEMICAL AND PHARMACOLOGICAL OVERVIEW OF ACEROLA CHERRY: A REVIEW
    NS Bhajipale, DB Sanghai, SS Padgilwar
    International Journal of Research in AYUSH and Pharmaceutical Sciences, 69-72 , 2017
    2017
  • Pharmacognostical, phytochemical and pharmacological overview: Cissus quadrangularis Linn.
    R Shukla, A Pathak, S Kambuja, S Sachan, A Mishra, S Kumar
    Indian Journal of Pharmaceutical and Biological Research 3 (3), 59 , 2015
    2015
    Citations: 16
  • Journal Of Harmonized Research (JOHR)
    R Shukla, S Sachan, A Mishra, S Kumar
    Journal Of Harmonized Research in Pharmacy 4 (1), 01-10 , 2015
    2015
  • Amniotic fluid derived stem cells as an organ specific regenerative medicine
    HM Takarani, NS Bhajipale
    2014
  • Antioxidant and hepatoprotective activity of extracts of flowers of Tridax procumbens Linn, against Dgalectosamine induced hepatotoxicity in male Wister albino rats
    NA Patel, SK Vaidya, S Kumar, AK Prasad, SB Bothara
    IAJPR 4 (49), 3712-3720 , 2014
    2014
    Citations: 7
  • Physicochemical, Phytochemical and toxicity studies on gum and mucilage from plant Abelmoschus esculentus
    S Kumar
    Extraction 55 (5) , 2014
    2014
    Citations: 19
  • Systematic pharmacognostical, phytochemical and pharmacological review on an ethno medicinal plant, Basella alba L
    S Kumar, AK Prasad, SV Iyer, SK Vaidya
    Journal of Pharmacognosy and Phytotherapy 5 (4), 53-58 , 2013
    2013
    Citations: 118
  • TLC/HPTLC finger print profile of chloroform extract of Vaidang Churna.
    RJ Sudani, SK Shankul Kumar, SV Iyer, G Vidyasagar
    2012
  • Pharmacognostical, phytochemical and pharmacological review on Bryophyllum pinnata
    AK Prasad, S Kumar, SV Iyer, RJ Sudani, SK Vaidya
    International Journal of Pharmaceutical & Biological Archives 3 (3), 423-433 , 2012
    2012
    Citations: 55
  • Pharmacognostical, phytochemical and pharmacological review on Tridax procumbens Linn
    S Kumar, A Prasad, SV Iyer, S Vaidya
    International Journal of Pharmaceutical & Biological Archives 3 (4), 747-51 , 2012
    2012
    Citations: 37
  • International Journal of Pharmaceutical Archive-1 (1), 2012, IJPAAvailable online through www. ijpaonline. info
    J Patel, S Kumar, H Patel, AK Prasad, SV Iyer, SK Vaidya
    2012
  • Anti ulcer activity of methanolic and aqueous extracts of leaves of Gymnema sylverstre in rats.
    UB Patel, AK Prasad, SK Shankul Kumar, SV Iyer, HA Patel, JA Patel
    2012
  • Pharmacognostical, phytochemical and pharmacological review on Tridax procumbens Linn.
    SK Shankul Kumar, AP Anuradha Prasad, SV Iyer, SV Santosh Vaidya
    2012

MOST CITED SCHOLAR PUBLICATIONS

  • Systematic pharmacognostical, phytochemical and pharmacological review on an ethno medicinal plant, Basella alba L
    S Kumar, AK Prasad, SV Iyer, SK Vaidya
    Journal of Pharmacognosy and Phytotherapy 5 (4), 53-58 , 2013
    2013
    Citations: 118
  • Pharmacognostical, phytochemical and pharmacological review on Bryophyllum pinnata
    AK Prasad, S Kumar, SV Iyer, RJ Sudani, SK Vaidya
    International Journal of Pharmaceutical & Biological Archives 3 (3), 423-433 , 2012
    2012
    Citations: 55
  • Pharmacognostical, phytochemical and pharmacological review on Tridax procumbens Linn
    S Kumar, A Prasad, SV Iyer, S Vaidya
    International Journal of Pharmaceutical & Biological Archives 3 (4), 747-51 , 2012
    2012
    Citations: 37
  • Antibacterial activity of leaves of BAMBOO.
    VK Singh, RS Rahul Shukla, V Satish, SK Shankul Kumar, ...
    2010
    Citations: 33
  • Comparative antidiabetic studies of leaves of Ipomoea carnea and Grewia asiatica on streptozotocin induced diabetic rats.
    AKA Latif, AK Prasad, SK Shankul Kumar, SV Iyer, HA Patel, JA Patel
    2012
    Citations: 22
  • Physicochemical, Phytochemical and toxicity studies on gum and mucilage from plant Abelmoschus esculentus
    S Kumar
    Extraction 55 (5) , 2014
    2014
    Citations: 19
  • Pharmacognostical, phytochemical and pharmacological overview: Cissus quadrangularis Linn.
    R Shukla, A Pathak, S Kambuja, S Sachan, A Mishra, S Kumar
    Indian Journal of Pharmaceutical and Biological Research 3 (3), 59 , 2015
    2015
    Citations: 16
  • Antibacterial activity of fresh leaves of Piper betle linn
    R Shukla, V Satish, VK Singh, S Kumar, S Gupta, U Gavani
    Pharma Res 1, 110 , 2009
    2009
    Citations: 15
  • Systemic review: Pharmacognosy, phytochemistry and pharmacology of Martynia annua
    S Kumar, AK Prasad, VS Iyer, A Sahu
    Int J Res Med 1 (1), 34-39 , 2012
    2012
    Citations: 10
  • Antioxidant and hepatoprotective activity of extracts of flowers of Tridax procumbens Linn, against Dgalectosamine induced hepatotoxicity in male Wister albino rats
    NA Patel, SK Vaidya, S Kumar, AK Prasad, SB Bothara
    IAJPR 4 (49), 3712-3720 , 2014
    2014
    Citations: 7
  • Pharmacognostical investigation on wheat grass
    S Kumar, V Satish, VDR Chandra, S Rahul, S Kambhoja, M Ashutosh
    International journal of Pharma and bio sciences 1 (2), 93-103 , 2010
    2010
    Citations: 7
  • Pharmacognostical, phytochemical and pharmacological review on Ipomoea carnea
    K Shankul, AK Prasad, SV Iyer, JA Patel, HA Patel, SK Vaidya
    Novus International Journal of Pharmaceutical Technology 1 (4), 9-18 , 2012
    2012
    Citations: 6
  • INDUSTRY 4.0: complex, disruptive, but inevitable. Management and Production Engineering Review, 11 (1), 43–51
    S Kumar, M Suhaib, M Asjad
    2020
    Citations: 5
  • Isolation of phytoconstituents from the aerial parts of Cocculus hirsutus Linn
    SV Iyer, K Shankul, PM Parikh
    J. Pharm. Res 4, 1946-1947 , 2011
    2011
    Citations: 5
  • Hypoglycaemic and hypolipidaemic potential of aerial parts of Amaranthus viridis (L.) Merr. in streptozotocin induced diabetic rats
    J Patel, S Kumar, H Patel, A Prasad, S Iyer, S Vaidya
    Int J Pharm Arch 1, 1-6 , 2012
    2012
    Citations: 4
  • Diffusion tensor fractional anisotropy is a potential surrogate marker for neuroinflammatory molecules in brain abscess
    AM Mishra, RK Gupta, K Nath, A Prasad, KM Hasan, KN Prasad, ...
    Proceedings of ISMRM 30 , 2006
    2006
    Citations: 4
  • Premix insulin analogue therapy in type 2 diabetes: Clinical observational study in routine practice
    SR Joshi, AK Das, A Bhattacharya, M Saikia, S Mukherji, M Patwardhan, ...
    Indian Journal of Endocrinology and Metabolism 8 (1), 20-27 , 2006
    2006
    Citations: 2
  • Phytochemical screening, investigations & antimicrobial activity on the various extracts obtained from the aerial parts of Alternanthera sessilis (Joyweed) and Crepidium …
    V Nigam, S Kumar, S Dubey, K Agarwal, S Chaurasia
    IP International Journal of Comprehensive and Advanced Pharmacology 8 (4 … , 2023
    2023
    Citations: 1
  • Isolation of novel alkaloid from methanolic extract of the aerial parts of Cocculus hirsutus Linn.
    SV Iyer, KS Kumar Shankul, UG Usha Gavani, PM Parikh
    2011
    Citations: 1
  • Analytical and bioactivity-based evaluation of Callistemon citrinus: HPTLC fingerprinting, marker quantification, and antioxidant potential of Hydroalcoholic extracts
    VK Prajapati, SR Singh, U Kumar, S Nain
    Journal of Chromatography B, 125065 , 2026
    2026