Muhammad Redza Mohd Radzi

@unimas.my

University Lecturer, Faculty of Resource Science and Technology
Universiti Malaysia Sarawak

Muhammad Redza Mohd Radzi


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https://researchid.co/redzaradzi

EDUCATION

Doctor of Philosophy (Bioscience)

RESEARCH, TEACHING, or OTHER INTERESTS

Cancer Research, Cell Biology, Molecular Biology, Biomaterials
5

Scopus Publications

55

Scholar Citations

4

Scholar h-index

1

Scholar i10-index

Scopus Publications

  • Biosynthesized Persicaria odorata-silver nanoparticles supported zeolite Y as biocompatible antibacterial agent against Cutibacterium acnes
    Muhammad Hariz Asraf, Nik Ahmad Nizam Nik Malek, Muhammad Redza Mohd Radzi, Hendra Susanto
    Particuology, 2024
  • Nanoparticles-based Chemo-Phototherapy Synergistic Effects for Breast Cancer Treatment: A Systematic Review
    Muhammad Redza, Muhammad Redza Mohd Radzi, Chun Soo Lim, Nadiah Sulaiman, Khairunadwa Jemon, et al.
    Biointerface Research in Applied Chemistry, 2023
    Despite the promising outcomes, conventional therapies for breast cancer treatment suffer from apparent limitations, including systemic toxicity, adverse reactions, and tumor recurrence. In light of that, therapy that combines chemo-phototherapy with nanoparticles is of immense value as it provides an alternative that hope exerts better outcomes. This review systematically assesses publications between 2010 and 2022, focusing on the application of nanoparticles in chemo-phototherapy for breast cancer. A detailed search was conducted in Scopus, PubMed, and WoS, and relevant studies within the 11 years were selected. Final 18 out of 40 initial papers were selected, including studies on in vivo analysis. Detailed information on chemo-phototherapy effects, drug cargo design, the toxicity of nanomaterials, and immunomodulatory effects were extracted and discussed. This review demonstrates the promising anticancer activity of combined synergistic effects for breast cancer management.
  • Polyethylene glycol modified-carbon nanotubes as materials for biomedical applications: In vitro and in vivo sub-acute toxicity evaluation
    Muhammad Redza Mohd Radzi, Yong Sin Yee, Mock Phooi Yan, Nur Amanina Johari, Wan Fatin Amira Wan Mohd Zawawi, Faridah Aminullah Lubis, Nur Afrina Muhamad Hendri, L. Santhana Raj, Khairunadwa Jemon
    Materials Letters, 2022
  • In vivo evaluation of oxidized multiwalled-carbon nanotubes-mediated hyperthermia treatment for breast cancer
    Muhammad Redza Mohd Radzi, Nur Amanina Johari, Wan Fatin Amira Wan Mohd Zawawi, Nurliyana Ahmad Zawawi, Nurriza Ab. Latiff, Nik Ahmad Nizam Nik Malek, Asnida Abdul Wahab, Maheza Irna Salim, Khairunadwa Jemon
    Biomaterials Advances, 2022
  • Preliminary evaluation on the EMT6 breast tumor inhibitory activity of carbon nanotubes with hyperthermia
    Muhammad Redza Mohd Radzi, Wan Fatin Amira Wan Mohd Zawawi, Nurliyana Ahmad Zawawi, Khairunadwa Jemon
    Aip Conference Proceedings, 2021
    Breast cancer is considered one of the most dangerous types of cancer with a high mortality rate among women worldwide. Potential alternative treatments such as hyperthermia (HT) often associated with poor specific heat distribution within the tumor microenvironment, thus reducing its anticancer potential. Owing to the fact that CNTs possessed high thermal conductivity, which could provide a uniform heat distribution, this study aims at exploring the combined effect of CNTs and HT in managing breast tumors. In this study, multiwalled CNTs were functionalized by acid washing protocol and validated by characterization analysis. Female Balb/c mice were inoculated with EMT6 breast cancer cells and then were intratumorally injected once with MWCNTs before being subjected to HT treatment for 3 consecutive days. Tumor progression and survival curves of mice were monitored. Our results demonstrated a successful functionalization of MWCNTs throughout dispersion, FTIR, TGA, XRD and FESEM analysis. Moreover, the combined-treated tumor showed complete eradication and prolonged survival median. The histological data revealed that combined treatment induced significant tumor necrosis post-treatment. Altogether, results from this preliminary study suggested that functionalized CNTs in combination with HT demonstrated a promising effect in eliminating EMT6 breast tumor.

RECENT SCHOLAR PUBLICATIONS

  • Extraction technologies and structural elucidation of polysaccharides from herbs and spices: Connecting molecular characteristics to biofunctional properties
    AHD Alias, ISAM Rizal, MA Yusof, MRM Radzi, MH Shafie
    Carbohydrate Research, 109963 , 2026
    2026
  • Biosynthesized Persicaria odorata-silver nanoparticles supported zeolite Y as biocompatible antibacterial agent against Cutibacterium acnes
    MH Asraf, NANN Malek, MRM Radzi, H Susanto
    Particuology 93, 1-10 , 2024
    2024
    Citations: 9
  • Nanoparticles-based chemo-phototherapy synergistic effects for breast cancer treatment: A systematic review
    MRM Radzi, CK Lim, N Sulaiman, K Jemon
    Biointerface Res. Appl. Chem 13, 232 , 2023
    2023
    Citations: 5
  • Polyethylene glycol modified-carbon nanotubes as materials for biomedical applications: In vitro and in vivo sub-acute toxicity evaluation
    MRM Radzi, YS Yee, MP Yan, NA Johari, WFAWM Zawawi, FA Lubis, ...
    Materials Letters 326, 132979 , 2022
    2022
    Citations: 4
  • In vivo evaluation of oxidized multiwalled-carbon nanotubes-mediated hyperthermia treatment for breast cancer
    MRM Radzi, NA Johari, WFAWM Zawawi, NA Zawawi, NA Latiff, ...
    Biomaterials Advances 134, 112586 , 2022
    2022
    Citations: 37
  • Nanoparticles-based Chemo-Phototherapy Synergistic Effects for Breast Cancer Treatment: A Systematic
    MRM Radzi, CK Lim, N Sulaiman, K Jemon
    2022
  • Preliminary evaluation on the EMT6 breast tumor inhibitory activity of carbon nanotubes with hyperthermia
    MRM Radzi, WFAWM Zawawi, NA Zawawi, K Jemon
    AIP Conference Proceedings 2353 (1), 020002 , 2021
    2021

MOST CITED SCHOLAR PUBLICATIONS

  • In vivo evaluation of oxidized multiwalled-carbon nanotubes-mediated hyperthermia treatment for breast cancer
    MRM Radzi, NA Johari, WFAWM Zawawi, NA Zawawi, NA Latiff, ...
    Biomaterials Advances 134, 112586 , 2022
    2022
    Citations: 37
  • Biosynthesized Persicaria odorata-silver nanoparticles supported zeolite Y as biocompatible antibacterial agent against Cutibacterium acnes
    MH Asraf, NANN Malek, MRM Radzi, H Susanto
    Particuology 93, 1-10 , 2024
    2024
    Citations: 9
  • Nanoparticles-based chemo-phototherapy synergistic effects for breast cancer treatment: A systematic review
    MRM Radzi, CK Lim, N Sulaiman, K Jemon
    Biointerface Res. Appl. Chem 13, 232 , 2023
    2023
    Citations: 5
  • Polyethylene glycol modified-carbon nanotubes as materials for biomedical applications: In vitro and in vivo sub-acute toxicity evaluation
    MRM Radzi, YS Yee, MP Yan, NA Johari, WFAWM Zawawi, FA Lubis, ...
    Materials Letters 326, 132979 , 2022
    2022
    Citations: 4
  • Extraction technologies and structural elucidation of polysaccharides from herbs and spices: Connecting molecular characteristics to biofunctional properties
    AHD Alias, ISAM Rizal, MA Yusof, MRM Radzi, MH Shafie
    Carbohydrate Research, 109963 , 2026
    2026
  • Nanoparticles-based Chemo-Phototherapy Synergistic Effects for Breast Cancer Treatment: A Systematic
    MRM Radzi, CK Lim, N Sulaiman, K Jemon
    2022
  • Preliminary evaluation on the EMT6 breast tumor inhibitory activity of carbon nanotubes with hyperthermia
    MRM Radzi, WFAWM Zawawi, NA Zawawi, K Jemon
    AIP Conference Proceedings 2353 (1), 020002 , 2021
    2021