Pratip Shil

@niv.co.in

Scientist D, Bioinformatics & Data Management
ICMR National Institute of Virology

Pratip Shil


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https://researchid.co/pshil

EDUCATION

M.Sc (Physics) with Biophysics Specialization (2001)
Ph.D (Physics) with Biophysics Specialization (2007)

RESEARCH INTERESTS

Mathematical modelling applications in Virology including disease modelling, climate effects on viral diseases, vectors and vector-borne diseases. Bioinformatics: in silico antigen-antibody interaction studies.
34

Scopus Publications

764

Scholar Citations

17

Scholar h-index

25

Scholar i10-index

Scopus Publications

  • Identification of B-cell epitopes of Indian Zika virus strains using immunoinformatics
    Rohan Raj Roy, Nitali Tadkalkar, Gururaj Rao Deshpande, Nitin M. Atre, Pratip Shil, Gajanan Sapkal
    Frontiers in Immunology, 2025
    IntroductionThe Zika virus is an emerging Flavivirus known to cause Zika infection in humans. It is associated with severe health problems such as microcephaly and Guillain-Barré syndrome post the Brazilian epidemic in 2015-16. The spread of the Zika virus to the Asian subcontinent, especially to India is a matter of great concern. Two recent co-circulating Indian Zika virus strains such as Rajasthan and Maharashtra detected in 2018 and 2021 were studied to identify B-cell epitopes in the envelope and non-structural 1 protein as these epitopes are major indicators of robust humoral immune response. The study aimed at identifying novel epitopes, followed by molecular docking with potent Zika virus-specific monoclonal antibodies. The novel epitopes identified in this study shall be essential in designing multi-epitope vaccines capable of inducing antibody response against Zika virus infection.MethodsABCpred, BepiPred 2.0 and Kolaskar-Tongaonkar methods were used for predicting the linear B-cell epitopes, and Discotope 2.0 and ElliPro were used for the prediction of conformational epitopes. Linear epitopes were further checked for protective antigenicity, allergenicity and toxicity. Based on the stringent study design criteria, only the novel epitopes were considered for molecular docking with complementary determining regions of potent Zika virus-specific monoclonal antibodies.ResultsNineteen linear and five conformational epitopes were shortlisted based on protective potential, non-allergic and non-toxic properties for Zika virus E protein, from which nine linear and three conformational epitopes were identified as novel. Molecular docking studies revealed that the novel linear epitopes, one each from EDIII, EDII, EDI and EDI/DIII hinge were involved in epitope-CDR interactions with potent neutralizing Zika virus E-specific mouse monoclonal antibody ZV-67. Moreover, the novel EDII epitope was exclusively engaged in epitope-CDR interactions of potent neutralizing Zika virus E-specific human monoclonal antibody Z3L1. None of the linear epitopes of Zika virus NS1 were ascertained as novel based on our study criteria. Conformational epitopes were identified as novel for NS1 protein.ConclusionThis study identified Zika virus-specific novel epitopes of envelope and non-structural -1 proteins in the currently co-circulating Indian strains. Furthermore, in-silico validation through molecular docking added insight into antigen-antibody interactions, paving way for future in vitro and in vivo studies.
  • Structural and functional characterization of avian influenza H9N2 virus neuraminidase with a combination of five novel mutations
    Deeksha S. Tare, Shailesh D. Pawar, Pratip Shil, Nitin M. Atre
    Archives of Biochemistry and Biophysics, 2024
  • Genomic Characterization of Mosquito Isolates of Chikungunya Virus (Outbreak Strains 2022) Using Next-Generation Sequencing
    Amol Nath, Surendra Kumar, Yogesh K. Gurav, Abhranil Gangopadhayya, Onkar Ghuge, Pallipurathu R. Sreelakshmi, Abhijeet Jadhav, Lekshmi S. Rajan, Kishore Yadav, Krishna Shinde, Pratip Shil, Anakkathil Sudeep, Kavita S. Lole
    Vector Borne and Zoonotic Diseases, 2023
    Background: A massive outbreak of dengue-like illness was reported from Pune district of Maharashtra, India during May-June 2022. Isolation and characterization of the etiological agent at genomic level for possible mutations that led to higher transmissibility is the topic of the study. Methods: Entomological investigations were carried out by ICMR-National Institute of Virology (Pune, India); Aedes aegypti mosquitoes were collected and processed for virus detection by molecular techniques. Positive mosquito pools were processed for virus isolation in cell culture. Sanger sequencing and whole-genome sequencing (WGS) using Oxford Nanopore Technology platform were used for genomic characterization. Results: Reverse transcriptase RT-PCR and qRT-PCR analysis detected chikungunya virus (CHIKV) in mosquito samples. Six CHIKV isolates were obtained. WGS revealed four nonsynonymous mutations in the structural polyprotein region, and five in the nonstructural polyprotein encoding region when compared with Yawat-2000 and Shivane-2016 strains. Sixty-four nucleotide changes in the nonstructural polyprotein region and 35 in the structural polyprotein region were detected. One isolate had an exclusive amino acid change, T1123I, in the nsP2 (protease) region. Conclusion: Abundant Ae. aegypti breeding and detection of CHIKV RNA in mosquitoes confirmed it as a chikungunya outbreak. Novel mutations detected in the epidemic strain warrants investigations to address their role in disease severity, transmission, and fitness.
  • Diversity ofsandfliesinVidarbha region of Maharashtra,India, a region endemic to Chandipura virus encephalitis
    A. Sudeep, P. Shil, K. Selarka, Y. S. Godke, P. Sonawane, M. Gokhale
    Indian Journal of Medical Research, 2023
    Background & objectives Sandflies are implicated as vectors of Chandipura virus (CHPV) (Vesiculovirus: Rhabdoviridae). The virus is prevalent in central India including Vidarbha region of Maharashtra. CHPV causes encephalitis in children below 15 yr of age with case fatality rates ranging from 56 to 78 per cent. The present study was undertaken to determine the sandfly fauna in the CHPV endemic Vidharba region. Methods A year round survey of sandflies was conducted at 25 sites in three districts of Vidarbha region. Sandflies were collected from their resting sites using handheld aspirators and identified using taxonomical keys. Results A total of 6568 sandflies were collected during the study. Approximately 99 per cent of the collection belonged to genus Sergentomyia, which was represented by Ser. babu, Ser. bailyi and Ser. punjabensis. Genus Phlebotomus was represented by Ph. argentipes and Ph. papatasi. Ser. babu was the predominant species (70.7%) collected during the study. Ph. argentipes was detected in four villages with 0.89 per cent, whereas Ph. papatasi was detected in only one village with 0.32 per cent of the total collection. CHPV could not be isolated despite processing all the sandflies for virus isolation in cell culture. Interpretation & conclusions The present study showed influence of higher temperature and relative humidity on sandfly population dynamics. An important observation during the study was the absence or decline in the population of Ph. papatasi and Ph. argentipes in the study area. Surge in Sergentomyia population and their breeding/resting in close vicinity to humans pose a concern as they are known to harbour CHPV and other viruses of public health importance.
  • ArVirInd-a database of arboviral antigenic proteins from the Indian subcontinent
    Nitin Motilal Atre, Kalichamy Alagarasu, Pratip Shil
    Peerj, 2022
    Background Studies on antigenic proteins for arboviruses are important for providing diagnostics and vaccine development. India and its neighboring countries have a huge burden of arboviral diseases. Data mining for country-specific sequences from existing bioinformatics databases is cumbersome and time-consuming. This necessitated the development of a database of antigenic proteins from arboviruses isolated from the countries of the Indian subcontinent. Methods Arboviral antigenic protein sequences were obtained from the NCBI and other databases. In silico antigenic characterization was performed (Epitope predictions) and data was incorporated into the database. The front end was designed and developed using HTML, CSS, and PHP. For the backend of the database, we have used MySQL. Results A database, named ArVirInd, is created as a repository of information on curated antigenic proteins. This enlists sequences by country and year of outbreak or origin of the viral strain. For each entry, antigenic information is provided along with functional sites, etc. Researchers can search this database by virus/protein name, country, and year of collection (or in combination) as well as peptide search for epitopes. It is available publicly via the Internet at http://www.arvirind.co.in. ArVirInd will be useful in the study of immune informatics, diagnostics, and vaccinology for arboviruses.
  • Epidemiological findings for the first and second waves of COVID-19 pandemic in Maharashtra, India
    Pratip Shil, Nitin M Atre, Babasaheb V Tandale
    Spatial and Spatio Temporal Epidemiology, 2022
  • District-wise estimation of Basic reproduction number (R0) for COVID-19 in India in the initial phase
    Pratip Shil, Nitin M. Atre, Avinash A. Patil, Babasaheb V. Tandale, Priya Abraham
    Spatial Information Research, 2022
    SARS-CoV-2 or COVID-19 was introduced into India by multiple sources generating local clusters and leading to the nationwide spread. A retrospective study has been conducted on the epidemiological features and spatial spread of COVID-19 in India during February 2020–March 2021. For each district, the cumulative number of confirmed COVID-19 cases were fitted to exponential growth model for the initial phase of the outbreak (the first 7–15 days). From the estimated growth rate, epidemiological parameters like the Basic reproduction number (R0) and epidemic doubling time (τ) were determined. Using Q-GIS software, we have generated the all India distribution maps for R0 and τ. COVID-19 spread rapidly covering majority of the districts of India between March and June 2020. As on 1st March 2021, a total of 715 out of 717 districts have been affected. The R0 range is at par with the global average. A few districts, where outbreaks were caused by migrant workers coming home, intense transmission was recorded R0 > 7. We also found that the spread of COVID-19 was not uniform across the different districts of India. The methodology developed in the study can be used by researchers and public health professionals to analyze and study epidemics in future.
  • Design of a multi-epitope peptide vaccine candidate against chandipura virus: an immuno-informatics study
    Daya V. Pavitrakar, Nitin M. Atre, Anuradha S. Tripathy, Pratip Shil
    Journal of Biomolecular Structure and Dynamics, 2022
    Chandipura virus (CHPV) is an emerging pathogen responsible for acute encephalitic syndrome (AES) in pediatric population in India. Several outbreaks of CHPV have been reported from different states of India since the year 2003. At present there is no vaccine or therapeutic measures available to curtail the disease. In this study, we have identified both T-cell and B-cell epitopes of different antigenic proteins of CHPV like Nucleoprotein (N), Phosphoprotein (P) and Matrix protein (M) along with the immuno-dominant glycoprotein (G) and conducted in silico characterization for the same. The idea is to design a multi-epitope peptide construct using the epitopes, which were found to be non-toxic, non-allergenic and possessing high immunogenicity. The final multi-epitope construct named as: MEC-CHPV, comprised of β-defensin adjuvant at N-terminal for enhancement of immunogenicity followed by fourteen B-cell epitopes, four Helper T-cell epitopes and six Cytotoxic T-cell epitopes. The characterization of designed construct was carried out in terms of physicochemical parameters, antigenicity and allergenicity. The 3D structure prediction was performed. Molecular docking and molecular-dynamics simulation of MEC-CHPV with Toll like receptors (TLR-3 and TLR-8) showed stable interactions. In silico cloning of MEC-CHPV in pET30a(+) expression vector was also conducted using codon optimization. The in silico immune-simulation indicated a typical immune response against MEC-CHPV when used as a potential vaccine. This study provides a cost-effective and time-saving way to design a peptide vaccine candidate against CHPV using immuno-informatics approach. Development of the MEC-CHPV construct may pave the way for future laboratory experiments. Communicated by Ramaswamy H. Sarma.
  • Cyclophilin A: a possible host modulator in Chandipura virus infection
    Daya V. Pavitrakar, Nitin M. Atre, Anuradha S. Tripathy, Pratip Shil
    Archives of Virology, 2021
    Chandipura virus (CHPV), belonging to the genus Vesiculovirus of the family Rhabdoviridae, has been identified as one of the causes of pediatric encephalitis in India. Currently, neither vaccines nor therapeutic drugs are available against this agent. Considering that the disease progresses very fast with a high mortality rate, working towards the development of potential therapeutics against it will have a public health impact. Although the use of viral inhibitors as antiviral agents is the most common way to curb virus replication, the mutation-prone nature of viruses results in the development of resistance to antiviral agents. The recent development of proteomic platforms for analysis of purified viral agents has allowed certain upregulated host proteins that are involved in the morphogenesis and replication of viruses to be identified. Thus, the alternative approach of inhibition of host proteins involved in the regulation of virus replication could be explored for their therapeutic effectiveness. In the current study, we have evaluated the effect of inhibition of cyclophilin A (CypA), an immunophilin with peptidyl-prolyl cis/trans-isomerase activity, on the replication of CHPV. Treatment with cyclosporin A, used in vitro for the inhibition of CypA, resulted in a 3-log reduction in CHPV titer and an undetectable level of CypA in comparison to an untreated control. An in silico analysis of the interaction of the CHPV nucleoprotein with the human CypA protein showed stable interaction in molecular docking and molecular dynamics simulations. Overall, the results of this study suggest a possible role of CypA in facilitating CHPV replication, thus making it one of the potential host factors to be explored in future antiviral studies. Supplementary information The online version contains supplementary material available at 10.1007/s00705-021-05237-1.
  • Predictions of Disease Spikes Induced by Climate Variability: A Pilot Real Time Forecasting Model Project from Maharashtra, India
    Sujata Saunik, Pratip Shil, Subrata N. Das, Sangita P. Rajankar, Omkar Khare, Krishna A. Hosalikar, Yusuf Kabir
    Global Issues in Water Policy, 2021
    Climate change is manifest globally through extreme weather events, altered rainfall patterns and spread of viral diseases. The emergence and re-emergence of arthropod-borne viral diseases viz. dengue, chikungunya, West Nile, Japanese encephalitis and Zika are of global public health concern. Over the last decade India has faced a huge burden of Dengue and chikungunya with more than ten million individuals affected. This not only necessitates studies on the role of environmental effects on disease, but also requires policy-framing towards effective prevention or control of epidemics. In this chapter we are presenting the initiative taken by the Government of Maharashtra state, Republic of India to establish a pilot project to record and document disease outbreaks in the different districts of the state and to develop a predictive model that can analyse the effect of meteorological parameters on disease occurrences. A web portal has been developed for recording of data and online display and efforts are on to develop mathematical models for analyses and estimation disease occurrences. As a first, we have successfully developed a Poisson regression model to describe the effects of meteorological parameters on dengue occurrences in the Nagpur region of the Maharashtra state.
  • Involvement of dual serotypes during a severe dengue outbreak in Wadi area, Nagpur district, Maharashtra 2017
    AB Sudeep, P Shil, MM Charmode, S Mohandas, S Bansod, MD Gokhale, M Jagtap, PS Shah
    Journal of Vector Borne Diseases, 2019
  • Assessment of NS1 protein as an early diagnostic marker for Kyasanur forest disease virus
    Devendra Mourya, Pragya Yadav, Gouri Chaubal, Sarita Jena, Pratip Shil
    Journal of Vector Borne Diseases, 2019
  • Differential susceptibility & replication potential of Vero E6, BHK-21, RD, A-549, C6/36 cells & Aedes aegypti mosquitoes to three strains of chikungunya virus
    AnakkathilBalan Sudeep, PratikB Vyas, Deepti Parashar, Pratip Shil
    Indian Journal of Medical Research, 2019
  • Complete genome sequencing of Kaisodi virus isolated from ticks in India belonging to Phlebovirus genus, family Phenuiviridae
    P.D. Yadav, D.A. Nyayanit, A.M. Shete, S. Jain, T.P. Majumdar, G.Y. Chaubal, P. Shil, P.M. Kore, D.T. Mourya
    Ticks and Tick Borne Diseases, 2019
  • Identification of a conserved neutralizing epitope in the G-protein of Chandipura virus
    Daya V. Pavitrakar, Rekha G. Damle, Anuradha S. Tripathy, Pratip Shil
    Archives of Virology, 2018
  • Differences in Type I interferon response in human lung epithelial cells infected by highly pathogenic H5N1 and low pathogenic H11N1 avian influenza viruses
    Milind M. Thube, Pratip Shil, Rewati Kasbe, Avinash A. Patil, Shailesh D. Pawar, Jayati Mullick
    Virus Genes, 2018
  • Rainfall and Chikungunya incidences in India during 2010–2014
    Pratip Shil, Dilip R. Kothawale, Anakkathil B. Sudeep
    Virusdisease, 2018
  • Numerical analyses of electroporation-mediated doxorubicin uptake in eukaryotic cells: Role of membrane cholesterol content
    Indian Journal of Biochemistry and Biophysics, 2018
  • Bioinformatics characterization of envelope glycoprotein from kyasanur forest disease virus
    DevendraT Mourya, Pratip Shil, PragyaDhruv Yadav, AvinashA Patil, R Balasubramanian
    Indian Journal of Medical Research, 2018
  • Aedes vittatus (Bigot) mosquito: An emerging threat to public health
    AB Sudeep, P Shil
    Journal of Vector Borne Diseases, 2017
  • Influenza A(H1N1)pdm09 outbreak detected in inter-seasonal months during the surveillance of influenza-like illness in Pune, India, 2012-2015
    Y. K. GURAV, M. S. CHADHA, B. V. TANDALE, V. A. POTDAR, S. D. PAWAR, P. SHIL, A. R. DEOSHATWAR, R. AARTHY, A. BHUSHAN
    Epidemiology and Infection, 2017
  • In-vitro effect of human cathelicidin antimicrobial peptide LL-37 on dengue virus type 2
    K. Alagarasu, P.S. Patil, P. Shil, M. Seervi, M.B. Kakade, H. Tillu, A. Salunke
    Peptides, 2017
  • Radio-electro-chemotherapy of cancer: New perspectives for cancer treatment
    P. Vidyasagar, S. Jagtap, O. Yemul
    Radiation in Medicine and Biology, 2017
  • Zika virus: Indian perspectives
    DevendraT Mourya, Pratip Shil, GajananN Sapkal, PragyaD Yadav
    Indian Journal of Medical Research, 2016
  • Design and characterization of polytope construct with multiple B and T H epitopes of Japanese encephalitis virus
    Reshma Kulkarni, Gajanan Sapkal, Lata Mahishi, Pratip Shil, Milind M. Gore
    Virus Research, 2012
  • Induction of virus-specific neutralizing immune response against West Nile and Japanese encephalitis viruses by chimeric peptides representing T-helper and B-cell epitopes
    Roopesh Singh Gangwar, Pratip Shil, Gajanan N. Sapkal, Siraj A. Khan, Milind M. Gore
    Virus Research, 2012
  • Delineation of an epitope on domain I of Japanese Encephalitis Virus envelope glycoprotein using monoclonal antibodies
    Roopesh Singh Gangwar, Pratip Shil, Sarah S. Cherian, Milind M. Gore
    Virus Research, 2011
  • Transmission dynamics of novel influenza A/H1N1 2009 outbreak in a residential school in India
    Current Science, 2011
  • Analysing the effects of surface distribution of pores in cell electroporation for a cell membrane containing cholesterol
    Pratip Shil, Salil Bidaye, Pandit B Vidyasagar
    Journal of Physics D Applied Physics, 2008
  • ISHAN: Sequence homology analysis package
    In Silico Biology, 2006
  • Electroporation enhances radiation and doxorubicin-induced toxicity in solid tumor in vivo
    Pratip Shil, Amit Kumar, Pandit B. Vidyasagar, Kaushala Prasad Mishra
    Journal of Environmental Pathology Toxicology and Oncology, 2006
  • Evolution of ribulose bisphosphate carboxylase/oxygenase (RuBisCO) large chains: In silico study
    Physiology and Molecular Biology of Plants, 2005
  • Sci‐AM Fri ‐ 03: Radio‐electro therapy of murine fibrosarcoma: In vivo study
    P Vidyasagar, P Shil, K Mishra
    Medical Physics, 2005
  • Enhancement of radiation cytotoxicity in murine cancer cells by electroporation: In vitro and in vivo studies
    Pratip Shil, Surendra H. Sanghvi, Pandit B. Vidyasagar, Kaushala Prasad Mishra
    Journal of Environmental Pathology Toxicology and Oncology, 2005

RECENT SCHOLAR PUBLICATIONS

  • Identification of B-cell epitopes of Indian Zika virus strains using immunoinformatics
    RR Roy, N Tadkalkar, GR Deshpande, NM Atre, P Shil, G Sapkal
    Frontiers in Immunology 16, 1534737 , 2025
    2025
    Citations: 9
  • Structural and functional characterization of avian influenza H9N2 virus neuraminidase with a combination of five novel mutations
    DS Tare, SD Pawar, P Shil, NM Atre
    Archives of biochemistry and biophysics 757, 110041 , 2024
    2024
    Citations: 1
  • Genomic characterization of mosquito isolates of chikungunya virus (Outbreak Strains 2022) using next-generation sequencing
    A Nath, S Kumar, YK Gurav, A Gangopadhayya, O Ghuge, ...
    Vector-Borne and Zoonotic Diseases 23 (6), 341-349 , 2023
    2023
    Citations: 7
  • Diversity of sandflies in Vidarbha region of Maharashtra, India, a region endemic to Chandipura virus encephalitis
    AB Sudeep, P Shil, K Selarka, YS Godke, PA Sonawane, MD Gokhale
    Indian Journal of Medical Research 157 (4), 259-267 , 2023
    2023
    Citations: 16
  • ArVirInd—a database of arboviral antigenic proteins from the Indian subcontinent
    NM Atre, K Alagarasu, P Shil
    PeerJ 10, e13851 , 2022
    2022
    Citations: 3
  • Epidemiological findings for the first and second waves of COVID-19 pandemic in Maharashtra, India
    P Shil, NM Atre, BV Tandale
    Spatial and Spatio-temporal Epidemiology 41, 100507 , 2022
    2022
    Citations: 16
  • Design of a multi-epitope peptide vaccine candidate against chandipura virus: an immuno-informatics study
    DV Pavitrakar, NM Atre, AS Tripathy, P Shil
    Journal of Biomolecular Structure and Dynamics 40 (2), 648-659 , 2022
    2022
    Citations: 23
  • Cyclophilin A: a possible host modulator in Chandipura virus infection
    DV Pavitrakar, NM Atre, AS Tripathy, P Shil
    Archives of virology 166 (11), 3143-3150 , 2021
    2021
    Citations: 12
  • Predictions of disease spikes induced by climate variability: a pilot real time forecasting model project from Maharashtra, India
    S Saunik, P Shil, SN Das, SP Rajankar, O Khare, KA Hosalikar, Y Kabir
    Management of Irrigation and Water Supply Under Climatic Extremes: Empirical … , 2021
    2021
    Citations: 2
  • Forecasting Model Project from Maharashtra, India
    S Saunik, P Shil, SN Das, SP Rajankar, O Khare, KA Hosalikar, Y Kabir
    Management of Irrigation and Water Supply Under Climatic Extremes: Empirical … , 2021
    2021
  • Climate influence on Dengue occurrence in Pune Urban Zone: development of a SARIMA based forecasting model
    P Shil, M Jagtap, P Awate
    Dengue Bulletin 42, 108-125 , 2021
    2021
  • District-wise estimation of Basic reproduction number (R0) for COVID-19 in India in the initial phase
    P Shil, N Atre, A Patil, B Tandale, P Abraham
    Spatial Information Research, doi.org/10.1007/s41324-021-00412-7 , 2021
    2021
    Citations: 13
  • Meteorological Parameters and Mosquito Species Diversity and Abundance along the Arabian Sea Coastline of Alappuzha District, India: A Year-round Study (2017-18)
    P Shil, R Balasubramanian
    Journal of Mosquito Research 10 , 2020
    2020
    Citations: 4
  • Climate and dengue in the Pune region: prospects for an early warning system
    P Shil, M Jagtap, CRH deSouza, AB Sudeep, P Awate
    Dengue Bulletin 41, 49-76 , 2020
    2020
    Citations: 3
  • Involvement of dual serotypes during a severe dengue outbreak in Wadi area, Nagpur district, Maharashtra 2017
    AB Sudeep, P Shil, MM Charmode, S Mohandas, S Bansod, MD Gokhale, ...
    Journal of Vector Borne Diseases 56 (4), 295-302 , 2019
    2019
    Citations: 4
  • Assessment of NS1 protein as an early diagnostic marker for Kyasanur forest disease virus
    P Yadav, G Chaubal, S Jena, S Pratip, D Mourya
    Journal of Vector Borne Diseases 56 (3), 212-220 , 2019
    2019
    Citations: 2
  • Rainfall and dengue occurrences in India during 2010–2016
    P Shil
    Biomedical Research Journal 6 (2), 56-61 , 2019
    2019
    Citations: 20
  • Differential susceptibility & replication potential of Vero E6, BHK-21, RD, A-549, C6/36 cells & Aedes aegypti mosquitoes to three strains of chikungunya virus
    AB Sudeep, PB Vyas, D Parashar, P Shil
    Indian Journal of Medical Research 149 (6), 771-777 , 2019
    2019
    Citations: 30
  • Complete genome sequencing of Kaisodi virus isolated from ticks in India belonging to Phlebovirus genus, family Phenuiviridae
    PD Yadav, DA Nyayanit, AM Shete, S Jain, TP Majumdar, GY Chaubal, ...
    Ticks and tick-borne diseases 10 (1), 23-33 , 2019
    2019
    Citations: 48
  • Identification of a conserved neutralizing epitope in the G-protein of Chandipura virus
    DV Pavitrakar, RG Damle, AS Tripathy, P Shil
    Archives of virology 163 (12), 3215-3223 , 2018
    2018
    Citations: 7

MOST CITED SCHOLAR PUBLICATIONS

  • In-vitro effect of human cathelicidin antimicrobial peptide LL-37 on dengue virus type 2.
    K Alagarasu, PS Patil, P Shil, et. al..
    Peptides 92, 23-30 , 2017
    2017
    Citations: 100
  • Aedes vittatus (Bigot) mosquito: An emerging threat to public health
    AB Sudeep, P Shil
    Journal of Vector Borne Diseases 54 (4), 295-300 , 2017
    2017
    Citations: 75
  • Zika virus: Indian perspectives
    DT Mourya, P Shil, GN Sapkal, PD Yadav
    Indian Journal of Medical Research 143 (5), 553-564 , 2016
    2016
    Citations: 50
  • Complete genome sequencing of Kaisodi virus isolated from ticks in India belonging to Phlebovirus genus, family Phenuiviridae
    PD Yadav, DA Nyayanit, AM Shete, S Jain, TP Majumdar, GY Chaubal, ...
    Ticks and tick-borne diseases 10 (1), 23-33 , 2019
    2019
    Citations: 48
  • Analysing the effects of surface distribution of pores in cell electroporation for a cell membrane containing cholesterol
    P Shil, S Bidaye, PB Vidyasagar
    Journal of Physics D: Applied Physics 41 (5), 055502 , 2008
    2008
    Citations: 43
  • Differential susceptibility & replication potential of Vero E6, BHK-21, RD, A-549, C6/36 cells & Aedes aegypti mosquitoes to three strains of chikungunya virus
    AB Sudeep, PB Vyas, D Parashar, P Shil
    Indian Journal of Medical Research 149 (6), 771-777 , 2019
    2019
    Citations: 30
  • Design of a multi-epitope peptide vaccine candidate against chandipura virus: an immuno-informatics study
    DV Pavitrakar, NM Atre, AS Tripathy, P Shil
    Journal of Biomolecular Structure and Dynamics 40 (2), 648-659 , 2022
    2022
    Citations: 23
  • Electroporation enhances radiation and doxorubicin-induced toxicity in solid tumor in vivo
    P Shil, A Kumar, PB Vidyasagar, KP Mishra
    Journal of environmental pathology, toxicology and oncology 25 (4) , 2006
    2006
    Citations: 23
  • Enhancement of radiation cytotoxicity in murine cancer cells by electroporation: in vitro and in vivo studies
    P Shil, SH Sanghvi, PB Vidyasagar, KP Mishra
    Journal of environmental pathology, toxicology and oncology 24 (4) , 2005
    2005
    Citations: 22
  • Rainfall and Chikungunya incidences in India during 2010–2014
    P Shil, DR Kothawale, AB Sudeep
    Virusdisease 29 (1), 46-53 , 2018
    2018
    Citations: 21
  • Molecular basis of antigenic drift in Influenza A/H3N2 strains (1968-2007) in the light of antigen antibody interactions
    P Shil, S Chavan, S Cherian
    Bioinformation 6 (7), 266 , 2011
    2011
    Citations: 21
  • Rainfall and dengue occurrences in India during 2010–2016
    P Shil
    Biomedical Research Journal 6 (2), 56-61 , 2019
    2019
    Citations: 20
  • Influenza A (H1N1) pdm09 outbreak detected in inter-seasonal months during the surveillance of influenza-like illness in Pune, India, 2012–2015
    YK Gurav, MS Chadha, BV Tandale, VA Potdar, SD Pawar, P Shil, ...
    Epidemiology & Infection 145 (9), 1898-1909 , 2017
    2017
    Citations: 19
  • Mathematical Modeling of Viral Epidemics: A Review
    P Shil
    Biomed Res J 3 (2), 195–215 , 2016
    2016
    Citations: 19
  • Delineation of an epitope on domain I of Japanese encephalitis virus Envelope glycoprotein using monoclonal antibodies
    RS Gangwar, P Shil, SS Cherian, MM Gore
    Virus research 158 (1-2), 179-187 , 2011
    2011
    Citations: 19
  • Transmission dynamics of novel influenza A/H1N1 2009 outbreak in a residential school in India
    P Shil, YK Gurav, MS Chadha, AC Mishra
    Current Science, 1177-1183 , 2011
    2011
    Citations: 19
  • Antigenic variability in Neuraminidase protein of Influenza A/H3N2 vaccine strains (1968–2009)
    P Shil, SS Chavan, SS Cherian
    Bioinformation 7 (2), 76 , 2011
    2011
    Citations: 18
  • Induction of virus-specific neutralizing immune response against West Nile and Japanese encephalitis viruses by chimeric peptides representing T-helper and B-cell epitopes
    RS Gangwar, P Shil, GN Sapkal, SA Khan, MM Gore
    Virus research 163 (1), 40-50 , 2012
    2012
    Citations: 17
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