Experienced Professor with a demonstrated history of working in the herbal medical practice industry. Skilled in Drug Design, Drug Discovery, Quality Control, Formulation, and Nutraceuticals. Strong education professional with a Master of Business Administration - MBA focused in Clinical research management from Xavier Institute of Management and also having the knowledge of interpretation of Modern analytical parameters of Herbal and Herbo mineral formulations.
EDUCATION
MD, PhD -Ayurved Rasashastra and Bhaishajyakalpana
MBA - Clinical Research management
PGDPM - Post graduate diploma in Pharmaceutical Management
9
Scopus Publications
38
Scholar Citations
3
Scholar h-index
1
Scholar i10-index
Scopus Publications
Critical review on Druti Kalpana (liquification technics) of Rasadravyas explained in different texts of Rasashastra Prasanna Mathad, K Manjunath Journal of Ayurveda and Holistic Medicine, 2025 Rasashastra is a branch of science which deals with the detail study of metals and minerals along with their formulations, among these formulations the Acharyas has mentioned Bhasma, pisti, pottali, kupipakwa kalpana etc. Among them Drutis occupies as an important formulation. Druti is a basic principle of Rasashastra and remain as an important pharmaceutical process. There are various dosage forms like Churna, Guti, Vati, Kwatha, Bhasma, Pottali, Sindura etc described in the classics of Rasashastra and Bhaishajya Kalpana. Druti is one of the main yet neglected dosage form of Ayurveda pharmaceutics mentioned in the Rasashastra classics. Druti is mentioned in some classics like Rasaratna Samuchhaya, Rasa Prakasha Sudhakara, Ayurveda Prakasha, Rasa marthanda etc; but detailed procedure for all the Drutis are not found. Ratnadruti is also not vividly explained in the classics. Druti is employed for both Dehasiddhi and Lohasiddhi. It is also said that Druti preparation is difficult without the grace of lord shiva. This article is aimed at discussing some of the concepts of Druti kalpana and an attempt has been made to approach the concept through reviews from various Ayurvedic classical texts, published articles and other sources.
A review of Uparatnas in Rasashastra Navneet Patidar, Mayur Barve, Prasanna Mathad Journal of Ayurveda and Holistic Medicine, 2025 Background:Rasashastra, a unique alchemical science of Ayurveda, mainly deals with the preparation and use of various formulations derived from metals, minerals, or those of a metallo-mineral origin. In addition to these, a special category has also been separately mentioned, which not only holds astrological importance but is also used for treating different ailments. Ratnas (precious stones) and Uparatnas (semi-precious stones) belong to this category. Various Acharyas have mentioned about nine Ratnas and seven Uparatnas. However, due to the high cost and rare availability of Ratnas, routine use of formulations containing Ratnas such as Navaratnarajamriganka Rasa has become rare in regular practice.Aims: The current article focuses on the compilation of Uparatnas from various sources to evaluate their utility in Rasashastra.Methods and Material:An exclusive review of the available books of Rasashastra such as Ayurved Prakasha, Rasa Prakashika, etc was done to compile the available literature on Uparatnas. Results: It was observed that Uparatnas have more or less similar properties to that of Ratnas. On the other hand, Uparatnas are abundantly available and more cost-effective.Conclusions:Hence if Uparatnas are used more in routine practice, they can prove to be a better alternative to Ratnas.
Cytotoxicity Evaluation of Green-synthesized MgO Nanoparticles with the Combination of Curcuma, Cardamom, and Pippali for Potential Cardioprotective Therapy in Diabetes-associated CVDs Insha Khan, Prasanna Mathad, Ravi Vijayvargia, Nivedita Priya Open Medicinal Chemistry Journal, 2025 Introduction Diabetes mellitus increases the risk of Cardiovascular Diseases (CVDs), highlighting the need for new treatments. Herbal remedies like turmeric (Curcuma longa), with its bioactive compound curcumin, are known for their anticoagulant effects. Cardamom (Elettaria cardamomum) helps lower diastolic blood pressure and inflammatory markers linked to CVDs. Pippali (Piper longum) acts as an anti-inflammatory, analgesic, and bioenhancer. In the current study, acknowledging their properties, these three herbs were combined (Curc+Card+Pip) and conjugated with green-synthesized MgO nanoparticles from curry leaves (Murraya koenigii). The aim was to evaluate the cytotoxicity of the herbal combination with and without MgONPs before employing it as a potential novel therapeutic approach for CVD-related research in diabetes. Methods This case-control study included two groups: a) normoglycemic individuals and b) those with Type 2 Diabetes Mellitus (T2DM). Hydroethanolic extracts were prepared and characterized. Cytotoxicity of Curc+Card+Pip and Curc+Card+Pip+MgONps was assessed using the MTT assay over 24 and 48 hours at concentrations of 100-500 µg/ml. Peripheral Blood Mononuclear Cells (PBMCs) from both groups were used as the primary cell lines. Statistical analysis was conducted using SPSS 26.0 and Excel 2021. Results The MTT assay on PBMCs from Normoglycemic (NG) and T2DM groups with i) Curc+Card+Pip and ii) Curc+Card+Pip+MgONps showed minimal cytotoxicity at concentrations of 100-500 µg/ml. The CC50 order was NG 24 hours >; T2DM 24 hours >; NG 48 hours >; T2DM 48 hours. A significant difference in cell viability was observed between 24 hours (96.45% ± 0.012) and 48 hours (73.62% ± 0.48) at 100 µg/ml in NG (p >; 0.01), while T2DM showed 93.63% ± 0.012 and 68.41% ± 0.048 at 24 and 48 hours, respectively. For NG, Curc+Card+Pip+MgONps exhibited viabilities of 92.75% ± 0.026 and 62.02% ± 0.046 at 24 and 48 hours, respectively, while T2DM showed 90.82% ± 0.018 and 59.44% ± 0.044. Discussion Cytotoxicity increased from 100-500 µg/ml, reducing viability. Cytotoxicity increased at 400-500 µg/ml at 48 hours (p >; 0.001) in both groups and treatments, suggesting that cell tolerance to MgO NPs was similar to that without NPs. The herbal mixture with MgONPs displayed a cytotoxicity pattern similar to that of the mixture without NPs in both groups. Conclusion The CC50 for Cur+Card+Pip without and with NPs was 452 and 410 µg/ml, respectively, within 24 hours, whereas in T2DM patients, the same treatments were found to have CC50 values of 300 and 330 µg/ml, respectively, with and without NPs. The values were the same in the case of T2DM (48 hours), whether it was with or without NPs (CC50 = 240 µg/ml), allowing for future exploration of its anti-inflammatory and antioxidant effects on PBMCs, which could suggest its potential as an alternative therapy for managing CVD in diabetic patients.
A Double-blind, Randomized Controlled Study of Triterpenoids based Standardized Gotu Kola Leaves Extract in the Patients with Tension Type Headache Prasad Thakurdesai, Pallavi Deshpande, Namrata Desai, Prasanna Mathad, Sandhya Rani, Dhananjay Raje Pharmacognosy Journal, 2024 Introduction:Triterpenoid-based standardized Centella asiatica leaves extract as nasal solution (INDCA-NS) has shown potential in animal models of stress-related disorders.Objective: Efficacy and safety evaluation of INDCA-NS in patients with Tension-type headache (TTH).Methods: Ninety-one patients with TTH were randomized and administered INDCA-NS (46 patients) or PLACEBOCA-NS (45 patients) nasal spray (400 g/day, 100 g in 100 L shot/ nostril, twice daily) for 28 days, with a 14-day follow-up.Efficacy (headache duration, frequency, and intensity; 21-item "Depression, Anxiety, and Stress Scale" (DASS-21); "Work Productivity and Activity Questionnaire" (WPAI: SHP); "World Health Organization Brief" (WHOQOL-BREF), cortisol and DHEA levels, rescue medications), and safety outcome measures (including adverse events) were monitored.Results: Subacute administration of INDCA-NS (but not PLACEBOCA-NS) significantly reduced the duration of headache and TTH's effect of TTH on WPAI:SHP (Q5) scores, namely productivity in working patients (P < 0.05, within the groups).The INDCA-NS showed significant difference (P < 0.05) in headache duration with and without covariate adjustment (vs.PLACEBOCA-NS).Both treatments found safe, well-tolerated, with no treatment-related adverse events, significantly reduced headache frequency, pain intensity, DASS-21 (stress domain), TTH's impact on daily activities (Q6 of WPAI:SHP), and improved WHOQOL scores (P < 0.05, within the group).The other outcome measures were not statistically significant within or between groups.Conclusion: Subacute INDCA-NS reduced headache duration and improved work productivity in TTH patients.
COMPARATIVE CYTOTOXICITY OF Curcuma longa AND Elettaria cardamomum EXTRACTS CONJUGATED WITH GREEN-SYNTHESIZED MGO NANOPARTICLES ON PBMCS: ENHANCED EFFICACY OF Elettaria cardamomum Insha Khan, Neha Mehta, Prasanna Mathad, Ravi Vijayvargia, Farida Khatri, Indrani Bhattacharya, Nivedita Priya Rasayan Journal of Chemistry, 2024 This study explores the efficacy of combination herbs like Turmeric (Curcuma longa) and Pippali (Piper longa) (Curc+pip), Cardamom (Elettaria cardamomum) and Pippali (Card+pip) conjugated with green synthesized MgO nanoparticles (MgONPs) as a novel treatment modality for cardiovascular diseases in the context of diabetes mellitus. The cytotoxicity of extracts conjugated with green-synthesized MgONPs was investigated. Extracts were synthesized using the Soxhlet method and further characterized by HPTLC. Curry leaves were used to green synthesize MgONPs and characterized by DLS and FTIR. Cytotoxicity of herbal concoction was assessed using the MTT assay on Peripheral Blood mononuclear cells, of Normoglycemic and Type 2 Diabetes Mellitus individuals. HPTLC results revealed the presence of 3-butylligusticumlactone, 16-hydroxymedicagenic acid, and Curcumin in Turmeric. Cardamom showed a strong presence of terpenoids and Isopiperine and piperine in Pippali. MgONPs (55nm) demonstrated fair stability. Volume-dependent MTT assay using Cur+Pip and Card+Pip extract with and without NPs results exhibited low cytotoxicity on both NG and T2DM participants. The combination of Cur+Pip with and without MgONPs at 5µL presented viability up to to73.07%±0.03, In the case of 75µL, it declined up to 7.34%±0.21 in 24 hrs. Similarly, Card+Pip, exhibited 92.3%±1.1 viability at 5µL post 24 hrs and in 48 hrs, dropped to 70.15%±2.02. The Differences in mean viabilities were found to be non-significant in the case of treatments with and without NPs, hence well tolerated by cells. The combination with minimal cytotoxicity may exhibit promising cardioprotective effects as an alternative therapy. Elettaria cardamomum emerges as a Promising Candidate.
Antioxidant, Antimicrobial, Antidiabetic, Antiglycation, and Biocompatibility Potential of Aqueous Zingiber officinale Rhizome (AZOME) Extract Mohd Hasan Mujahid, Tarun Kumar Upadhyay, Vijay Jagdish Upadhye, Prasanna Sriram Mathad Journal of Angiotherapy, 2024 Background: The rhizome of Zingiber officinale or ginger shows its potential against oxidative stress, microbial infections, and managing diabetes mellitus. Method: Chemical reagents and plant materials of analytical grade were procured. Aqueous extract of Zingiber officinale rhizome was prepared through maceration. FT-IR, heavy metal detection, UV-VIS spectroscopy, and carbohydrate estimation were performed. Antimicrobial activity against bacterial and fungal strains was evaluated using agar diffusion method. Total polyphenol, flavonoid, and flavonol contents were quantified. Antioxidant activity was assessed using DPPH, reducing power, and FRAP assays. Antidiabetic activity was determined by α-amylase and α-glucosidase inhibition. Cytotoxicity, glucose uptake, and antiglycation assays were conducted on L6 cells. Blood compatibility was tested on human RBCs. Results: The analysis showed total phenolic content (TPC) at 27.9±0.27 mg/g GAE, total flavonoid content (TFC) at 18.4 mg/g QE, and total flavonol content (TFolC) at 41.1±4 mg/g QE. The extract demonstrated potent antioxidant activity with IC50 values of 353 µg/mL (DPPH), 600 µg/mL (H2O2 scavenging), and displayed antidiabetic effects inhibiting α-amylase (IC50=1564.43 µg/mL) and α-glucosidase (IC50=581.4 µg/mL). Cytotoxicity assays yielded an IC50 of 533.3 µg/mL (NRU assay) and highest glucose uptake at 254.74±62.79 µg/mL (L6 cells). The extract showed minimal hemolytic activity (-0.305±0.031%) and high cell viability (99%). In silico docking revealed strong interactions with targeted proteins. Conclusion: In conclusion, the aqueous extract of Zingiber officinale rhizome exhibits diverse pharmacological activities including antioxidant, antimicrobial, antidiabetic, and antiglycation properties, along with notable bio-safety and cytotoxicity profiles.
Investigation on the impact of swimming on children with ADHD Pradeep Marwaha, Malcolm Homavazir, Prasanna Mathad, Nidhi Sharma, Pooja Varma Multidisciplinary Science Journal, 2024 Attention deficit hyperactivity disorder (ADHD) represents a neurological condition that often affects children between the ages of two and three and twelve or thirteen and is linked with deficits in social, emotional, and cognitive development. The effectiveness of alternative therapy for this illness is mostly unknown. The possibility of using exercise as a treatment for ADHD in children has gained popularity in recent years. The study looked into how adaptive swimming affected the academic achievement, cognitive functioning, and associated behaviours in Indian children diagnosed with attention deficit hyperactivity disorder. At the time of the study, children with ADHD ranged in age from nine to twelve. They were split up into test and control groups at random. Reading and math abilities were evaluated before and after the intervention using the hailing exam. At the same time, cognitive function was measured using the Children's Behaviour Checklist (CBCL) to evaluate ADHD-related behaviours. The outcomes showed that the experimental therapy group outperformed the control group in terms of behaviour management and academic achievement. They provide preliminary support for the hypothesis that adaptive swimming benefits brain function, behaviour, and educational outcomes. Practitioners may be able to utilize the findings of this study as early evidence in favour of alternative treatment methods. The results also support that engaging in physically active hobbies might help children with ADHD.
Autism Spectrum Disorder from a Psychological Lens: Cognitive, Emotional, and Social Factors Swarup Kumar Bisoi, Vaibhav Kaushik, Madhur Grover, Manashree Mane, Vishal Biswas, Prasanna Mathad, S.A. Jadhav Health Leadership and Quality of Life, 2024 An intricate, varied illness called autism spectrum disorder influences interactions with others, nonverbal and verbal communication, thinking, comprehension of information, and social as well as cognitive behaviours. The study of the Theory of mind focuses on seeing, comprehending, and analysing mental events and the actions that follow from them. Research examines the cognitive, emotional, and social aspects of autism spectrum disorder via a psychological lens. The current study concentrates on how mind theory relates to the psychological, social, & cognitive growth of kids with autism spectrum disorder. The results of this investigation emphasize that there is a relationship between the Theory of mind and how well a -person's psychological, social, and cognitive abilities work. Hence, deficiencies in a kid's social interactions and intellectual and cognitive abilities systems are related to the restricted growth are observed in Mind Theory which has seen in autistic children. As a consequence, a viable alternative treatment technique involves taking a concentrated, comprehensive approach to their shortcomings while also using information and communication technologies.
Antibiotics in Livestock Production: A Comprehensive Examination of Usage, Resistance, and Regulatory Imperatives for Enhanced Oversight Revista Electronica De Veterinaria, 2023
RECENT SCHOLAR PUBLICATIONS
Analytical Standardization and In-Vitro Antimicrobial Assessment of Easy V Gel: A Polyherbal Formulation A Kantharia¹, M Karkare, P Mathad 2026
The Mapping of the concepts and its Application of Ashtanga yoga with Blooms taxonomy DPM Dr Anagha Mathad , Dr Amit Upasani The Bioscan 20 (4), 2094-2102 , 2025 2025
Probiotics as Next-Generation Allies in Poultry Health: A Systematic Review of Microbial Therapies for Sustainable Disease Control T Ahmed, MH Mujahid, PS Mathad Microbial Bioactives 8 (1), 1-9 , 2025 2025
Critical review on Druti Kalpana (liquification technics) of Rasadravyas explained in different texts of Rasashastra P Mathad, K Manjunath Journal of Ayurveda and Holistic Medicine (JAHM) 13 (7), 28-36 , 2025 2025
A review of Uparatnas in Rasashastra N Patidar, M Barve, P Mathad Journal of Ayurveda and Holistic Medicine (JAHM) 13 (6), 118-129 , 2025 2025
Cytotoxicity Evaluation of Green-synthesized MgO Nanoparticles with the Combination of Curcuma, Cardamom, and Pippali for Potential Cardioprotective Therapy in Diabetes … I Khan, P Mathad, R Vijayvargia, N Priya The Open Medicinal Chemistry Journal 19 (1) , 2025 2025
Development and Phytochemicl Analysis of a Novel Herbal Medhya (Memory booster)-Chocolate DAM Dr Prasanna Mathad African Journal of Biomedical research 28 (2), 421-424 , 2025 2025
COMPARATIVE EFFICACY OF ABHYANGA AND ABHYANGA COMBINED WITH PHYSIOTHERAPY IN THE MANAGEMENT OF JANUSANDHIGATA VATA: A RANDOMIZED INTERVENTIONAL STUDY A Mathad, BG Kulkarni, P Mathad, A Upasani 2025
Preparation And Phytochemical Analysis of Palandwadi Nasal Spray DSD Dr. Divya.B1*, Dr. Prasanna Mathad2 African Journal of Biomedical research 28 (1), 2746-2749 , 2025 2025
COMPARATIVE CYTOTOXICITY OF Curcuma longa AND Elettaria cardamomum EXTRACTS CONJUGATED WITH GREEN-SYNTHESIZED MGO NANOPARTICLES ON PBMCS: ENHANCED EFFICACY OF Elettaria … IBNP Insha Khan1 , Neha Mehta , Prasanna Mathad , Ravi Vijayvargia , Farida ... Rasayna journal of chemistry 17 (4), 2051-2061 , 2024 2024
Autism Spectrum Disorder from a Psychological Lens: Cognitive, Emotional, and Social Factors SAJ Swarup Kumar Bisoi , Vaibhav Kaushik , Madhur Grover , Manashree Mane ... Health Leadership and Quality of Life 3 (407), 10 , 2024 2024
A Double-blind, Randomized Controlled Study of Triterpenoids based Standardized Gotu Kola Leaves Extract in the Patients with Tension Type Headache. P Thakurdesai, P Deshpande, N Desai, P Mathad, S Rani, D Raje Pharmacognosy Journal 16 (6), 1238 , 2024 2024 Citations: 1
ANTIBACTERIAL ACTIVITY OF GAMBHARIYADI YOGA HYPOTHETICAL VIEW MP YADAV K , TOSHIKHANE H IJBPAS 13 (11), 5703-5706 , 2024 2024
Comparative cytotoxicity of Curcuma longa and Elettaria cardamomum extracts conjugated with green-synthesized MgO nanoparticles on PBMCs: Enhanced efficacy of Elettaria cardamomum I Khan, N Mehta, P Mathad, R Vijayvargia, F Khatri, I Bhattacharya, ... Rasayan Journal of Chemistry 17 (4) , 2024 2024 Citations: 2
Investigation on the impact of swimming on children with ADHD PMMHPMNSP Varmae Multidisciplinary Science journal , 2024 2024
Investigation on the impact of swimming on children with ADHD P Marwaha, M Homavazir, P Mathad, N Sharma, P Varma Multidisciplinary Science Journal 6 , 2024 2024
Pharmaceutical Standardization of Rajata Bhasma (Incinerated Silver Ash) Prepared with Two Methods by Using Classical Heating and Muffle Furnace DJP Dr. Prasanna Mathad1 , Dr. Tanvi Dayanand2 , Dr. Rakesh B3 , Dr. Arathi ... Journal of Chemical Health Risks 14 , 2024 2024
Experimental study of Pruthvisara taila in excised wound model in Wistar albino rats PM Archana Pagad, Abhayakumar Mishra, Vinay R Kadibagil , Sudhakar Bhat International Journal of Ayurved Medicine 15 (1), 103-110 , 2024 2024 Citations: 1
AUTISM SPECTRUM DISORDER FROM A PSYCHOLOGICAL LENS: COGNITIVE, EMOTIONAL, AND SOCIAL FACTORS BS KUMAR, V KAUSHIK, M GROVER, M MANE, V BISWAS, P MATHAD, ... HEALTH 3 , 2024 2024
MOST CITED SCHOLAR PUBLICATIONS
Antibacterial activity of various leaf extract of Cajanus cajan L H Pratima, P Mathad Bioscan 6 (1), 111-114 , 2011 2011 Citations: 13
Antibiotics in livestock production: A comprehensive examination of usage, resistance, and regulatory imperatives for enhanced oversight P Belwal, P Mathad, M Jayashree REDVET-Rev Electron Vet 24, 2023 , 2023 2023 Citations: 5
CONTROVERSIES OF RASADRAVYA IN RASASHASTRA: A REVIEW DP Mathad International Journal of Research in Ayurveda and Pharmacy 10 (2), 21-22 , 2019 2019 Citations: 3
Comparative cytotoxicity of Curcuma longa and Elettaria cardamomum extracts conjugated with green-synthesized MgO nanoparticles on PBMCs: Enhanced efficacy of Elettaria cardamomum I Khan, N Mehta, P Mathad, R Vijayvargia, F Khatri, I Bhattacharya, ... Rasayan Journal of Chemistry 17 (4) , 2024 2024 Citations: 2
A review on medical astrology with respect to Arishta Lakshana A Anigol, P Mathad, R Chitree Int J Multidisciplinary Educ Res 5, 18-24 , 2020 2020 Citations: 2
A Double-blind, Randomized Controlled Study of Triterpenoids based Standardized Gotu Kola Leaves Extract in the Patients with Tension Type Headache. P Thakurdesai, P Deshpande, N Desai, P Mathad, S Rani, D Raje Pharmacognosy Journal 16 (6), 1238 , 2024 2024 Citations: 1
Experimental study of Pruthvisara taila in excised wound model in Wistar albino rats PM Archana Pagad, Abhayakumar Mishra, Vinay R Kadibagil , Sudhakar Bhat International Journal of Ayurved Medicine 15 (1), 103-110 , 2024 2024 Citations: 1
Chapala Nirnaya–An Experimental Study to Identify the Chapala P Mathad, MR Pandya Bull. Env. Pharmacol. Life Sci 12, 64-66 , 2023 2023 Citations: 1
Comparative Pharmaceutical and Analytical Study of Chapal Shodhan (Purification Process) with Special Reference to Bismuth and Selenium P Mathad, M R Pandya JPRI , 2021 2021 Citations: 1
Anti-Inflammatory activity of decoction and distillation of Triphala treated with gomutra A Mishra Book Rivers , 2021 2021 Citations: 1
Modulation of Agnilepa In The Managemant of Amavata S Deva, P Mathad, K Roy International Journal of Multidisciplinary Educational Research| Volume-9 … , 2020 2020 Citations: 1
Analytical Standardization and In-Vitro Antimicrobial Assessment of Easy V Gel: A Polyherbal Formulation A Kantharia¹, M Karkare, P Mathad 2026
The Mapping of the concepts and its Application of Ashtanga yoga with Blooms taxonomy DPM Dr Anagha Mathad , Dr Amit Upasani The Bioscan 20 (4), 2094-2102 , 2025 2025
Probiotics as Next-Generation Allies in Poultry Health: A Systematic Review of Microbial Therapies for Sustainable Disease Control T Ahmed, MH Mujahid, PS Mathad Microbial Bioactives 8 (1), 1-9 , 2025 2025
Critical review on Druti Kalpana (liquification technics) of Rasadravyas explained in different texts of Rasashastra P Mathad, K Manjunath Journal of Ayurveda and Holistic Medicine (JAHM) 13 (7), 28-36 , 2025 2025
A review of Uparatnas in Rasashastra N Patidar, M Barve, P Mathad Journal of Ayurveda and Holistic Medicine (JAHM) 13 (6), 118-129 , 2025 2025
Cytotoxicity Evaluation of Green-synthesized MgO Nanoparticles with the Combination of Curcuma, Cardamom, and Pippali for Potential Cardioprotective Therapy in Diabetes … I Khan, P Mathad, R Vijayvargia, N Priya The Open Medicinal Chemistry Journal 19 (1) , 2025 2025
Development and Phytochemicl Analysis of a Novel Herbal Medhya (Memory booster)-Chocolate DAM Dr Prasanna Mathad African Journal of Biomedical research 28 (2), 421-424 , 2025 2025
COMPARATIVE EFFICACY OF ABHYANGA AND ABHYANGA COMBINED WITH PHYSIOTHERAPY IN THE MANAGEMENT OF JANUSANDHIGATA VATA: A RANDOMIZED INTERVENTIONAL STUDY A Mathad, BG Kulkarni, P Mathad, A Upasani 2025