Atunwa, Soliu Abiola

@unilorin.edu.ng

Lecturer, Faculty of Pharmaceutical Sciences
Research Student, Others
University of Ilorin

Atunwa, Soliu Abiola


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Pharmacist Soliu Abiola ATUNWA ( is an aspiring, bright and promising young researcher. He is a passionate, upcoming scientist and astute lecturer in the Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Ilorin, Ilorin, Nigeria. He has keen interests in Behavioural and Cognitive Neurosciences (Neuropsychopharmacology); Ethnopharmacology/Drug Discovery, Design & Development; Public (Mental) Health/Pharmacoepidemiology; Pharmacology Education, Neuroscience Advocacy & Science Communication; and Community Pharmacy Practices. He is currently a Visiting Researcher to the Centre for Natural Products Discovery (CNPD), School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Liverpool, UK. His main research focus is to discover and develop novel therapeutics from natural products and rich Nigerian medicinal plants biodiversity for the management of neurodegenerative and neurological disease conditions with bias in dementia

EDUCATION

1. Obafemi Awolowo University, Ile-Ife, Nigeria 2019 - 2024
2. Obafemi Awolowo University, Ile-Ife, Nigeria 2013 - 2016
3. Obafemi Awolowo University, Ile-Ife, Nigeria 2004 - 2010
4. Obaseeku High School, Eruwa, Oyo State, Nigeria 1996 - 2002

RESEARCH, TEACHING, or OTHER INTERESTS

General Pharmacology, Toxicology and Pharmaceutics, Pharmacology, Toxicology, Drug Discovery
3

Scopus Publications

184

Scholar Citations

6

Scholar h-index

4

Scholar i10-index

Scopus Publications

  • Nature of hematopoietic system alteration and organ damage induced by fungal filtrate of Pestalotiopsis microspora in vivo
    Garuba Taofeeq, Lateef Adebola Azeez, Atunwa Soliu Abiola, Lateef Abibat Yetunde, Kolawole Olajumoke Oluwabunmi, et al.
    Journal of Applied Pharmaceutical Science, 2021
    Taofeeq Garuba1, Adebola Azeez Lateef1, Soliu Abiola Atunwa2, Abibat Yetunde Lateef1, Olajumoke Oluwabunmi Kolawole1, Saheed Sabiu3* 1Department of Plant Biology, University of Ilorin, Ilorin, Nigeria. 2Department of Pharmacology and Toxicology, University of Ilorin, Ilorin, Nigeria. 3Department of Biotechnology and Food Science, Faculty of Applied Sciences, Durban University of Technology, Durban, South Africa.
  • Evaluation of the antidiarrheal activity of the leaf extract of parquetina nigrescens and formulation into oral suspensions
    Adeola Tawakalitu Kola-Mustapha, Yusuf Oluwagbenga Ghazali, Hameedat Taiye Ayotunde, Soliu Abiola Atunwa, Sukurat Olasumbo Usman
    Journal of Experimental Pharmacology, 2019
    Purpose Parquetina nigrescens (Pn) extract was evaluated for safety and antidiarrheal activity, formulated into stable suspensions, and characterized. Methods Acute toxicity of the extract based on Organization for Economic Cooperation and Development-423 guidelines was performed. The antidiarrheal effects of the extract on castor oil-induced diarrhea in four groups of Wistar rats were determined. The first and second groups received 5 and 200 mg/kg body weight (bw) of the extract, while the third and fourth groups received normal saline (5 mg/kg bw) and loperamide (5 mg/kg bw) as negative and positive controls, respectively. Pn extract was used at 1.25% w/v to formulate structured vehicle (carboxylmethylcellulose, polyvinylpyrrolidone and tragacanth) suspensions. The suspensions were tested for pharmacological activity and characterized. Results Acute toxicity gave a lethal dose 50 (LD50) that is greater than 300 and less than 2,000 mg/kg bw. A reduction in intestinal transit by 0.14 and 0.15% at 5 and 200 mg/kg of the extract was achieved as compared to an inhibition of 0.12% by 5 mg/kg loperamide. There was a dose-dependent decrease in the frequency of watery stool passed in castor oil-induced rats by 35.29% and 64.70% at 5 and 200 mg/kg, respectively. All the suspensions inhibited diarrhea, exhibiting a dose-dependent pattern and remained stable after 4 weeks. Their pH values ranged from 4.60±2.73 to 4.73±1.91, while viscosity ranged from 3.50±1.23 to 6.75±1.24 Pas at 60 rpm. Conclusion The results suggest that Pn possesses significant antidiarrheal activity. Suspensions of Pn were successfully formulated in structured vehicles and were effective in the control of diarrhea in Wistar rats.
  • Neuropharmacological effects of Nigerian honey in mice
    MA Akanmu, TA Olowookere, SA Atunwa, BO Ibrahim, OF Lamidi, et al.
    African Journal of Traditional Complementary and Alternative Medicines, 2011
    Honey is a natural sweet substance that bees produce by transforming flower nectar or other sweet secretions of plants. It has widespread use in traditional medicine in various parts of the world. It has been reported to assist in building the entire central nervous system. The beneficial effects of honey have been attributed to the possible polyphenolic contents and some other constituents. The geographical locations and the sources of plant nectars may contribute to the effects of honey samples. Thus, we evaluated the neuropharmacological effects of six samples of honey (10%, 20% and 40%(V)/v, p.o.) from three geographical locations of Nigeria using the following behavioral models: Novelty-induced behaviors (NIB), learning and memory, pentobarbital-induced hypnosis, anxiolytic, anticonvulsant, analgesic and antidepressant models in mice. The results showed that honey significantly (p< 0.05) decreased locomotion and rearing behaviors in NIB and amphetamine-induced locomotor activity when compared to the control group. Exploratory behavior was significantly increased in both holeboard and elevated plus maze but had no significant effect on spatial working memory. Honey sample from Umudike has significant hypnotic and anticonvulsant effects. The antinociceptive models (hot plate and tail flick tests) showed that the honey samples significantly increased the pain reaction time and naloxone blocked these central antinociceptive effects. The force swimming test showed that only the Idanre (ID) honey sample had antidepressant effect. In conclusion, some of these honey samples have central inhibitory property, anxiolytic, antinociceptive, anticonvulsant and antidepressant effects, thus may be used as nutraceutic. It can also be inferred that some of these effects are probably mediated through dopaminergic and opioidergic systems.

RECENT SCHOLAR PUBLICATIONS

  • Preliminary Phytochemistry, Elemental Analyses, Antioxidant, Cytotoxic and Antiproliferative Potentials of Phoenix dactylifera Linn. Seeds
    HAANSN 4. S. A. Atunwa., A. A. Abdullahi., A. D. Ayoku., S. S. Oladele., K ...
    Journal of Pharmaceutical Research, Development and Practice (JPRDP) 8 (01 … , 2026
    2026
  • Clinical Manifestations
    DX Guan, B Creese, CM Germain, CE Fischer, D Kossowska-Kuhn, ...
    Alzheimer's & dementia: the journal of the Alzheimer's Association 21, e105072 , 2025
    2025
  • The measurement of agitation in neurocognitive disorders: A systematic review
    DX Guan, B Creese, CM Germain, CE Fischer, D Kossowska‐Kuhn, ...
    Alzheimer's & Dementia 21, e105072 , 2025
    2025
  • Evaluation of the neurocognitive potential of extracts of phoenix dactylifera and parquetina nigrescens
    SA Atunwa, MA Akanmu
    Neuroscience 580, 19 , 2025
    2025
  • DETERMINANTS OF HEALTH-RELATED QUALITY OF LIFE (HRQOL) IN ADULT PATIENTS UNDERGOING ANTI-MALARIAL TREATMENT AT A SECONDARY HEALTHCARE FACILITY IN ILORIN, NIGERIA
    HB Giwa, HD Shittu, MO Babatunde, OM Jamiu, OM Aiyelero, ...
    Nigerian Journal of Pharmaceutical Sciences , 2025
    2025
  • Evaluation of the neurocognitive and neuroprotective potentials of selected Nigerian medicinal plants in experimental models of dementia
    SA Atunwa
    Alzheimer's & Dementia 19, e080714 , 2023
    2023
  • Evaluation of antioxidant, anti-inflammatory, and anticholinesterase activities of selected medicinal plants used in dementia
    S Atunwa, M Akanmu, A Kola-Mustapha, A Abdullahi, H Atunwa, ...
    JOURNAL OF NEUROCHEMISTRY 166, 70-70 , 2023
    2023
  • Cobalt-60 lymphocytes immuno-phenotypes/myeloid-lymphoid toxicities and countermeasure effects of aqueous extracts of Parquetina nigrescens, Camellia sinensis and Telfairia …
    IK Olatunbosun, L.O., Eltahir, G.A., Abdulraheem, A.A., Olalere, F.D., Lawal ...
    African Journal of Laboratory, Haematology, and Transfusion Science 2 (1), 1-14 , 2023
    2023
  • Haematological, serum biochemical and histopathological changes in acute and sub-chronic aqueous extract of oyster mushroom in male Wistar rats
    T Garuba, IT Olabanji, OM Awogboro, GS Olahan, SA Atunwa, OA Ahmed, ...
    Journal of Scientific Research 15 (1), 201-213 , 2023
    2023
    Citations: 4
  • Beneficial effects of a polyherbal formulation in the management of sickle cell disease
    AT Kola-Mustapha, MO Amali, SA Atunwa, I Ishola, LO Farayola, ...
    American Journal of Pharmacotherapy and Pharmaceutical Sciences 1 , 2022
    2022
  • Pattern of haemopoietic progenitor cells differentiation and differentiation enhancing effect of Telfairia occidentalis extract in irradiated guinea-pig
    LA Olatubosun, EAG Khalil, SA Atunwa, FD Olalere, SA Lawal, ...
    College of Health Sciences, University of Ilorin , 2021
    2021
  • Exploring the Potential Anti-dementia Roles of Selected Herbal Anti-inflammatory Remedies in Parkinson’s Disease: Hopes and Challenges: 458
    SA Atunwa
    Movement Disorders 36, S201 , 2021
    2021
  • Pharmacognostic and Anti-diabetic Studies of Chromolaena odorata Linn.(Asteraceae) Powdered Leaves in Alloxan-induced Diabetic Rats
    AA Abdullahi, BA Aremu, SA Atunwa, SO Usman, FAU Attah, BA Lawal, ...
    Nigerian Journal of Pharmaceutical Research 16 (S), 1-11 , 2021
    2021
    Citations: 1
  • Anti-nociceptive Potential of Ethanol Extract of Terminalia macroptera Guill&Perr (Combretaceae) Stem Bark in Mice
    SA Atunwa, MO Amali, SO Lawal, SO Usman, AI Olapade
    Nigerian Journal of Pharmaceutical Research 16 (S), 13-21 , 2021
    2021
  • Nature of hematopoietic system alteration and organ damage induced by fungal filtrate of Pestalotiopsis microspora in vivo
    T Garuba, AA Lateef, SA Atunwa, AY Lateef, OO Kolawole, S Sabiu
    Journal of Applied Pharmaceutical Science 11 (3), 084-091 , 2021
    2021
  • Formulation of an Analgesic Ointment of Diclofenac Using Shea Butter Obtained from Kernels of Vitellaria Paradoxa as a Base
    ASA Afosi, A. B., Orafidiya, O. O., Adeyemi I. O.
    Nigerian Journal of Pharmaceutical Sciences 20 (1), 53-65. , 2021
    2021
  • Haemopoietic Multi-Potent Stem Cells Differentiation-Enhancing Effects of Parquetina nigrescens, Camellia sinensis and Telfairia occidentalis Leaves Extracts
    LO Olatunbosun, EAG Khalil, FD Olalere, SA Atunwa, SA Lawal, ...
    Sciences 1 (1), 14-21 , 2021
    2021
  • Evaluation of the neurocognitive and neuroprotective potentials of selected Nigerian medicinal plants in preclinical models of learning and memory: Nonhuman/Natural products …
    SA Atunwa
    Alzheimer's & Dementia 16, e046119 , 2020
    2020
  • cytotoxicity and anti-proliferative studies of Crinum jagus L.(Amaryllidaceae) bulb extract
    KM Salawu, SA Atunwa, IO ENIAYEWU
    BIMA JOURNAL OF SCIENCE AND TECHNOLOGY GOMBE 4 (01), 131-140 , 2020
    2020
    Citations: 8
  • Standardization, Physicochemical, Elemental Analysis and Anti-diabetic activity of Powdered Leaves of Chromolaena odorata in Alloxan-induced diabetic Rats
    AA Abdullahi, BA Aremu, SA Atunwa, SO Usman, NS Njinga, FAU Attah, ...
    2020
    Citations: 1

MOST CITED SCHOLAR PUBLICATIONS

  • Neuropharmacological effects of Nigerian honey in mice
    MA Akanmu, TA Olowookere, SA Atunwa, BO Ibrahim, OF Lamidi, ...
    African Journal of Traditional, Complementary and Alternative Medicines 8 (3) , 2011
    2011
    Citations: 97
  • Evaluation of the antidiarrheal activity of the leaf extract of Parquetina nigrescens and formulation into oral suspensions
    AT Kola-Mustapha, YO Ghazali, HT Ayotunde, SA Atunwa, SO Usman
    Journal of experimental pharmacology, 65-72 , 2019
    2019
    Citations: 20
  • Safety and toxicity of aqueous leaf extracts of Camellia sinensis, Parquetina nigrescens and Telfairia occidentalis in mice
    OL Olayinka, EAG Khalil, A Majeed, O OA, A OO, N AB
    African Journal of Pharmacy and Pharmacology 12 (18), 208-220 , 2018
    2018
    Citations: 12
  • Phytochemical and anti-inflammatory studies of ethanol extract of Terminalia macroptera Guill. & Perr.(Combretaceae) stem bark in rats and mice
    S Usman, A Agunu, S Atunwa, S Hassan, A Sowemimo, K Salawu
    Nigerian Journal of Pharmaceutical Research 13 (2), 147-156 , 2017
    2017
    Citations: 11
  • Assessment of anxiolytic potential and acute toxicity study of combretum micranthum g. don. leaves (combretaceae) in mice
    MO Amali, SA Atunwa, OM Aiyelero, QA Omotesho
    IBRO Reports 7, 42 , 2019
    2019
    Citations: 9
  • cytotoxicity and anti-proliferative studies of Crinum jagus L.(Amaryllidaceae) bulb extract
    KM Salawu, SA Atunwa, IO ENIAYEWU
    BIMA JOURNAL OF SCIENCE AND TECHNOLOGY GOMBE 4 (01), 131-140 , 2020
    2020
    Citations: 8
  • Assessment of anxiolytic potential and acute toxicity study of Combretum micranthum G. Don. leaves (Combretaceae)
    MO Amali, SA Atunwa, QA Omotesho, EO Oyedotun, AI Olapade
    Journal of Medicinal Plants for Economic Development 4 (1), 1-8 , 2020
    2020
    Citations: 6
  • Haematological, serum biochemical and histopathological changes in acute and sub-chronic aqueous extract of oyster mushroom in male Wistar rats
    T Garuba, IT Olabanji, OM Awogboro, GS Olahan, SA Atunwa, OA Ahmed, ...
    Journal of Scientific Research 15 (1), 201-213 , 2023
    2023
    Citations: 4
  • Acute toxicity study and evaluation of the anxiolytic activity of the ethanol leave extract of Bryophyllum Pinnatum (Kurz) in mice
    MO Amali, SA Atunwa, MO Aiyelero, SO Usman, AI Olapade, ...
    Journal of Pharmaceufical Research, Development and Pracfice 3 (1), 27-35 , 2019
    2019
    Citations: 4
  • Phytochemical, antibacterial and anticonvulsant activity of the stem bark of Lannea kerstingii Engl. & k. Krause (anacadiaceae)
    NS Njinga, MI Sule, AO Shittu, MS David, MO Amali, AR Bolaji, ...
    Journal of Pharmacy & Bioresources 15 (2), 107-116 , 2018
    2018
    Citations: 3
  • Knowledge and practice of reporting of adverse drug reactions among community pharmacists in Ilorin, North-Central, Nigeria
    N Bello, SA Atunwa
    J Pharm Res Dev & Pract 2 (2), 41-51 , 2018
    2018
    Citations: 3
  • Heavy metal content of commonly consumed herbal bitters in Ilorin, Nigeria
    RO Ayanniyi, SO Folami, HA Olumoh-Abdul, SA Atunwa, IA Oreagba
    West African Journal of Pharmacy 28 (1), 141-148 , 2017
    2017
    Citations: 3
  • Pharmacognostic and Anti-diabetic Studies of Chromolaena odorata Linn.(Asteraceae) Powdered Leaves in Alloxan-induced Diabetic Rats
    AA Abdullahi, BA Aremu, SA Atunwa, SO Usman, FAU Attah, BA Lawal, ...
    Nigerian Journal of Pharmaceutical Research 16 (S), 1-11 , 2021
    2021
    Citations: 1
  • Standardization, Physicochemical, Elemental Analysis and Anti-diabetic activity of Powdered Leaves of Chromolaena odorata in Alloxan-induced diabetic Rats
    AA Abdullahi, BA Aremu, SA Atunwa, SO Usman, NS Njinga, FAU Attah, ...
    2020
    Citations: 1
  • An Evaluation of the Impact of Zinc and Copper Metal-Organic Frameworks (MOFs) on the Drug Release Profiles of Piroxicam
    S ATUNWA
    2020
    Citations: 1
  • Ketamine induced analgesia in mice at sub-psychotomimetic dose
    SA Atunwa, OI Adeyemi, AR Owolabi
    West African Journal of Pharmacology and Drug Research 32 (1), 30-36 , 2017
    2017
    Citations: 1
  • Preliminary Phytochemistry, Elemental Analyses, Antioxidant, Cytotoxic and Antiproliferative Potentials of Phoenix dactylifera Linn. Seeds
    HAANSN 4. S. A. Atunwa., A. A. Abdullahi., A. D. Ayoku., S. S. Oladele., K ...
    Journal of Pharmaceutical Research, Development and Practice (JPRDP) 8 (01 … , 2026
    2026
  • Clinical Manifestations
    DX Guan, B Creese, CM Germain, CE Fischer, D Kossowska-Kuhn, ...
    Alzheimer's & dementia: the journal of the Alzheimer's Association 21, e105072 , 2025
    2025
  • The measurement of agitation in neurocognitive disorders: A systematic review
    DX Guan, B Creese, CM Germain, CE Fischer, D Kossowska‐Kuhn, ...
    Alzheimer's & Dementia 21, e105072 , 2025
    2025
  • Evaluation of the neurocognitive potential of extracts of phoenix dactylifera and parquetina nigrescens
    SA Atunwa, MA Akanmu
    Neuroscience 580, 19 , 2025
    2025