Monika Chahar

@bmu.ac.in

Assistant Professor , Department of Chemistry
BABA MASTNATH UNIVERSITY

Monika Chahar


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https://researchid.co/parnika05

EDUCATION

M.Sc, Ph.D. in Chemistry

RESEARCH, TEACHING, or OTHER INTERESTS

Chemistry, Materials Science, Physical and Theoretical Chemistry, Analytical Chemistry
3

Scopus Publications

70

Scholar Citations

4

Scholar h-index

2

Scholar i10-index

Scopus Publications

  • Energy-efficient synthesis of ZnO nanoparticles using white ash gourd fruit extract for their medicinal and environmental applications
    RAVI KANT, Monika, Anuj Mittal, Seema
    Indian Journal of Chemistry Ijc, 2025
    This work reported the green synthesis of ZnO nanoparticles (NPs) using white ash gourd fruit juice. The synthesized NPs were characterized by various spectroscopic techniques like UV–visible, FTIR, Powder XRD and FE-SEM. These NPs displayed a prominent absorbance at 357 nm in UV–visible spectra. X-ray diffraction studies confirmed the formation of crystalline ZnO NPs with the wurtzite phase. The average particle size (D) of the synthesized ZnO NPs is found to be 40.48 nm. FE-SEM images revealed that synthesized ZnO NPs have nano-flaky structures. The prepared ZnO NPs achieved 99% photodegradation efficiency against MB dye in 90 min of irradiation of UV light. These synthesized NPs were also examined for three biological activities: Antimicrobial, antioxidant and anti-diabetic. Antimicrobial activity was found to be good to moderate. The synthesized ZnO NPs showed excellent anti-diabetic activity (α-amylase activity) compared to standard with IC50 value equal to 1.21µg/mL. For α-glucosidase, green synthesized ZnO NPs (IC50 value 0.23 µg/mL) exhibited excellent inhibition activity compared to standard Acarbose (IC50 value 0.24 µg/mL). ZnO NPs showed better antioxidant capability as well.
  • Analysis of good and bad fingerprint for identification of NIR based optical frameworks using Monte Carlo method
    Surbhi Goyal, Payal Rani, Monika Chahar, Khalid Hussain, Parvin Kumar, Jayant Sindhu
    Microchemical Journal, 2024
  • Quantitative structure activity relationship studies of androgen receptor binding affinity of endocrine disruptor chemicals with index of ideality of correlation, their molecular docking, molecular dynamics and ADME studies
    Surbhi Goyal, Payal Rani, Monika Chahar, Khalid Hussain, Parvin Kumar, Jayant Sindhu
    Journal of Biomolecular Structure and Dynamics, 2023
    Endocrine disrupter chemicals (EDCs) are both natural and man-made chemicals that mimic, block or interfere with human hormonal system. In the present manuscript, QSAR modeling was performed for the androgen disruptors that interfere with biosynthesis, metabolism or action of androgens that causes adverse effects on male reproductive system. A set of 96 EDCs that exhibited affinity towards androgen receptors (Log RBA) in rats were employed for carrying out QSAR studies using Hybrid descriptors (combination of HFG and SMILES) through Monte Carlo Optimization. Using index of ideality of correlation (TF2), five splits were formed and predictability of five models resulting from these splits was assessed by various validation parameters. Models resulted from first split was the top most one with R2validation = 0.7878. Structural attributes responsible for change in endpoint were studied by employing correlation weights of structural attributes. In order to further validate the model, new EDCs were designed using these attributes. In silico molecular modelling studies were performed to assess the detailed interactions with the receptor. The binding energies of all the designed compounds were observed to be better than lead and are in the range of -10.46 to -14.80. Molecular dynamics simulation of 100 ns was performed for ED01 and NED05. The results revealed that the protein-ligand complex bearing NED05 was more stable than lead ED01 exhibiting better interactions with the receptor. Further, in an attempt to assess their metabolism, ADME studies were evaluated using SwissADME. The developed model enables to predict the characteristics of designed compounds in an authentic way.Communicated by Ramaswamy H. Sarma.

RECENT SCHOLAR PUBLICATIONS

  • Biosynthesized metallic nanoparticles for sustainable environmental remediation: mechanisms, applications, and future perspectives
    R Nain, H Patel, M Chahar, S Kumar, D Rohilla, M Pal
    Discover Chemistry 2 (1), 124 , 2025
    2025
    Citations: 41
  • Synthesis And Bioactivity Of Isoxazole-Derived Carboxamide And Carbohydrazide Derivatives: A Comprehensive Study
    M Chahar, NC Talniya
    Educational Administration: Theory and Practice 30 (5), 9361-9371 , 2024
    2024
  • A Study Of The Heterocyclic Benzoxazole Derivatives Design, Synthesis, And Anti-Fungal Assessment
    M Chahar, N ChandraTalniya
    Educational Administration: Theory and Practice 30 (4), 2978-2988 , 2024
    2024
  • Exploring Oxazole-Derived Heterocycles: Synthesis Strategies and Diverse Biological Activities for Potential Therapeutic Applications
    M Muskan, M Chahar, NC Talniya
    NATURALISTA CAMPANO 28 (1), 1817-1827 , 2024
    2024
  • Analysis of good and bad fingerprint for identification of NIR based optical frameworks using Monte Carlo method
    S Goyal, P Rani, M Chahar, K Hussain, P Kumar, J Sindhu
    Microchemical Journal 196, 109549 , 2024
    2024
    Citations: 5
  • Quantitative structure activity relationship studies of androgen receptor binding affinity of endocrine disruptor chemicals with index of ideality of correlation, their …
    S Goyal, P Rani, M Chahar, K Hussain, P Kumar, J Sindhu
    Journal of Biomolecular Structure and Dynamics 41 (23), 13616-13631 , 2023
    2023
    Citations: 13
  • Design, Synthesis, and Evaluation of Isoxazole-Based Compounds for Exploring Novel Biological Activities and Pharmacokinetic Profiles
    MC Naina, NC Talniya
    Atomic Spectroscopy-Part C 44 (3), 197-206 , 2023
    2023
  • An Investigation on Optimization techniques used to recovery of cadmium from E-waste by Electrowinning process
    A Kumar, M Chahar, A Dhaka
    Eur. Chem. Bull. 12 (9), 1899-1910 , 2023
    2023
  • Electrowinning Process In Cadmium Recovery From E-Waste
    A Dhaka, DM Chahar, DA Kumar
    International Journal of Innovation In Engineering Research … , 2023
    2023
  • Synthesis Of Some New Thiazolyl Chromenone Derivatives By Using α,α- Dibromoketones
    Pooja, M Chahar, Parul, V Kiran, J Sangwan
    IJRTS Journal of Research 24 (1), 65-75 , 2023
    2023
  • Synthesis and characterisation of two component polyurethane coatings blended with phthalic anhydride formed with TDI
    MC Preeti, U Vashisht, AA Pooja
    International Journal of Materials Science 4 (1), 21-26 , 2023
    2023
  • α,α- Dibromoketones in the preparation of new hydrazinyl thiazole derivatives
    Parul, M Chahar, V Kiran, Pooja, J Sangwan
    IJRTS Journal of Research 23 (1), 30-37 , 2022
    2022
  • Synthetic Study of Bischromones using KI and I2
    M Chahar, A Narwal
    NeuroQuantology 20 (15), 4635 , 2022
    2022
  • Synthesis of Some new and facile thiadiazoles with the help of Iodobenzene diacetate
    M Chahar, V Kiran, J Sangwan
    NeuroQuantology 20 (11), 8561 , 2022
    2022
  • Kinetic study and Mechanistic Interpretation of Mono-4-Nitrophenyl Phosphate ester via Neutral species
    M Chahar
    NeuroQuantology 20 (9), 5445 , 2022
    2022
  • Research On Solid State Dye Laser Materials Synthesized from Raw Polymer Doped With Laser Dye
    A Ahlawat, M Chahar, N Sangwan, Pooja, Preeti, J Sangwan
    International Journal of Science, Mathematics and Technology Learning 30 (2 … , 2022
    2022
  • Preparation and Characterization of Castor Oil Based Polyurethane and Spectroscopic Characterization of Castor Oil Based Polyol
    Preeti, M Chahar, U Vashisht
    IJRTS Journal of Research 23 (1), 1-6 , 2022
    2022
  • Synthesis, Characterization and Applications of Adipic Acid and Thiourea Based Template Mediated Complexes Doped With Metal (II) Sulphates
    P Sindhu, M Chahar, S Singhal, N Gandhi
    Journal of Northeastern University 25 (4), 858-870 , 2022
    2022
  • Synthesis of Template Mediated Doped Complex with Thiourea and Phthalic Acid
    P Sindhu, M Chahar, S Singhal, Anjali Ahlawat
    Asian Journal of Organic & Medicinal Chemistry 7 (2), 1-7 , 2022
    2022
  • Study of Optical properties of saffron dye doped silica based material
    M Chahar, A Ahlawat
    GIS SCIENCE JOURNAL 9 (1), 72-79 , 2022
    2022

MOST CITED SCHOLAR PUBLICATIONS

  • Biosynthesized metallic nanoparticles for sustainable environmental remediation: mechanisms, applications, and future perspectives
    R Nain, H Patel, M Chahar, S Kumar, D Rohilla, M Pal
    Discover Chemistry 2 (1), 124 , 2025
    2025
    Citations: 41
  • Quantitative structure activity relationship studies of androgen receptor binding affinity of endocrine disruptor chemicals with index of ideality of correlation, their …
    S Goyal, P Rani, M Chahar, K Hussain, P Kumar, J Sindhu
    Journal of Biomolecular Structure and Dynamics 41 (23), 13616-13631 , 2023
    2023
    Citations: 13
  • Preparation and spectral investigations of neodymium oxide doped polymethylmethacrylate based laser material
    M Chahar, V Ali, S Kumar
    International Journal of Scientific and Research Publications 2, 2250-3153 , 2012
    2012
    Citations: 7
  • Analysis of good and bad fingerprint for identification of NIR based optical frameworks using Monte Carlo method
    S Goyal, P Rani, M Chahar, K Hussain, P Kumar, J Sindhu
    Microchemical Journal 196, 109549 , 2024
    2024
    Citations: 5
  • Spectral Investigations of Kiton red-620 doped Polymethylmethacrylate
    VASK Monika Chahar
    J. Materials Sciences and Applications 3 (10), 669-673 , 2012
    2012
    Citations: 4
  • Synthesis And Bioactivity Of Isoxazole-Derived Carboxamide And Carbohydrazide Derivatives: A Comprehensive Study
    M Chahar, NC Talniya
    Educational Administration: Theory and Practice 30 (5), 9361-9371 , 2024
    2024
  • A Study Of The Heterocyclic Benzoxazole Derivatives Design, Synthesis, And Anti-Fungal Assessment
    M Chahar, N ChandraTalniya
    Educational Administration: Theory and Practice 30 (4), 2978-2988 , 2024
    2024
  • Exploring Oxazole-Derived Heterocycles: Synthesis Strategies and Diverse Biological Activities for Potential Therapeutic Applications
    M Muskan, M Chahar, NC Talniya
    NATURALISTA CAMPANO 28 (1), 1817-1827 , 2024
    2024
  • Design, Synthesis, and Evaluation of Isoxazole-Based Compounds for Exploring Novel Biological Activities and Pharmacokinetic Profiles
    MC Naina, NC Talniya
    Atomic Spectroscopy-Part C 44 (3), 197-206 , 2023
    2023
  • An Investigation on Optimization techniques used to recovery of cadmium from E-waste by Electrowinning process
    A Kumar, M Chahar, A Dhaka
    Eur. Chem. Bull. 12 (9), 1899-1910 , 2023
    2023
  • Electrowinning Process In Cadmium Recovery From E-Waste
    A Dhaka, DM Chahar, DA Kumar
    International Journal of Innovation In Engineering Research … , 2023
    2023
  • Synthesis Of Some New Thiazolyl Chromenone Derivatives By Using α,α- Dibromoketones
    Pooja, M Chahar, Parul, V Kiran, J Sangwan
    IJRTS Journal of Research 24 (1), 65-75 , 2023
    2023
  • Synthesis and characterisation of two component polyurethane coatings blended with phthalic anhydride formed with TDI
    MC Preeti, U Vashisht, AA Pooja
    International Journal of Materials Science 4 (1), 21-26 , 2023
    2023
  • α,α- Dibromoketones in the preparation of new hydrazinyl thiazole derivatives
    Parul, M Chahar, V Kiran, Pooja, J Sangwan
    IJRTS Journal of Research 23 (1), 30-37 , 2022
    2022
  • Synthetic Study of Bischromones using KI and I2
    M Chahar, A Narwal
    NeuroQuantology 20 (15), 4635 , 2022
    2022
  • Synthesis of Some new and facile thiadiazoles with the help of Iodobenzene diacetate
    M Chahar, V Kiran, J Sangwan
    NeuroQuantology 20 (11), 8561 , 2022
    2022
  • Kinetic study and Mechanistic Interpretation of Mono-4-Nitrophenyl Phosphate ester via Neutral species
    M Chahar
    NeuroQuantology 20 (9), 5445 , 2022
    2022
  • Research On Solid State Dye Laser Materials Synthesized from Raw Polymer Doped With Laser Dye
    A Ahlawat, M Chahar, N Sangwan, Pooja, Preeti, J Sangwan
    International Journal of Science, Mathematics and Technology Learning 30 (2 … , 2022
    2022
  • Preparation and Characterization of Castor Oil Based Polyurethane and Spectroscopic Characterization of Castor Oil Based Polyol
    Preeti, M Chahar, U Vashisht
    IJRTS Journal of Research 23 (1), 1-6 , 2022
    2022
  • Synthesis, Characterization and Applications of Adipic Acid and Thiourea Based Template Mediated Complexes Doped With Metal (II) Sulphates
    P Sindhu, M Chahar, S Singhal, N Gandhi
    Journal of Northeastern University 25 (4), 858-870 , 2022
    2022