Bioactivity Modulation: Anionic Influence on Cu(II) Schiff Base Complexes Jesna K. Sebastian, S. R. Amrutha, N. R. Suja, Nithya Mohan, S. S. Sreejith, Maheswaran Sithambaresan, M. Priya, M. K. Muraleedharan Nair Applied Organometallic Chemistry, 2025 This article explains the synthesis of three Schiff base Cu(II) complexes derived from 3‐hydroxybenzaldehyde and ethylenediamine using three distinct copper anionic salts, and it explores the effects of those salts on the properties of the complexes. Elemental analysis, electronic spectra, FT‐IR, ESR, molar conductance, magnetic measurement, thermogravimetric analysis and PXRD were used to characterize the compounds. The anionic salt has been demonstrated to exhibit distinctive characteristics on Gram‐positive and Gram‐negative bacteria in terms of structure, DNA binding, cell viability, DNA breakage and activity. Furthermore, this ligand L1 and its derivatives indicated positive antifungal efficacy against Aspergillus niger and Trichophyton tonsurans. The study elucidates the manner in which distinct anion salts impacted the properties of complexes and their antifungal, anticancer and antibacterial outcomes.
A novel Salen-based dual channel sensor for easy and selective nanomolar detection of l-cysteine Nithya Mohan, S. S. Sreejith, M. R. Prathapachandra Kurup New Journal of Chemistry, 2024 A Salen-type Schiff base sensor, characterized by XRD, efficiently detects l-cysteine through static and dynamic fluorescence quenching, employing a FRET mechanism. It exhibits remarkable stability, with a low detection limit of 1.52 × 10−9 M.
Copper(ii) salen-based complexes as potential anticancer agents Nithya Mohan, C. V. Vidhya, V. Suni, Jimna Mohamed Ameer, Naresh Kasoju, P. V. Mohanan, S. S. Sreejith, M. R. Prathapachandra Kurup New Journal of Chemistry, 2022 The systematic design and synthesis of four Cu(ii) salen compounds and their potential as excellent anticancer agents is discussed using biological studies.
Copper salen-type complexes as protein-interactive anticancer agents: A molecular and experimental study N Mohan, SS Sreejith, MRP Kurup Journal of Molecular Structure, 144968 , 2025 2025
Mononuclear and trinuclear zinc (II) architectures derived from functionalized pyrazole-fenamic acid hybrids: Synthesis, structure, fluorescence, and bioactivity LK Suresh, N Mohan, M Sithambaresan, MRP Kurup Journal of Molecular Structure, 143844 , 2025 2025 Citations: 1
Fluorescence Sensing of Metal Ions Using Cyclodextrins N Mohan, SK Anand, SS Sreejith Cyclodextrins for Chemosensing, 143-165 , 2025 2025
Bioactivity Modulation: Anionic Influence on Cu (II) Schiff Base Complexes JK Sebastian, SR Amrutha, NR Suja, N Mohan, SS Sreejith, ... Applied Organometallic Chemistry 39 (3), e7853 , 2025 2025 Citations: 2
Multi-faceted investigation of copper (II) chelates based on ONS donor thiosemicarbazone: crystal structures, spectral aspects, DNA binding, cytotoxicity and computational studies JM Jacob, N Mohan, M Sithambaresan, E Manoj, MRP Kurup Journal of Molecular Structure 1319, 139463 , 2025 2025 Citations: 12
Pyrazolyl-derived zinc (II) and cadmium (II) complexes: Synthesis, spectral characterization, single crystal insights, Hirshfeld surface analysis, and in silico DNA interaction … LK Suresh, PK Maniyampara, N Mohan, M Simi, K Gopal, MRP Kurup, ... Inorganic Chemistry Communications 168, 112811 , 2024 2024 Citations: 3
Mononuclear and binuclear dioxidomolybdenum (VI) chelates derived from a tridentate ONO donor aroylhydrazone: Spectral, structural, DFT and in silico biological investigations AA Aravindakshan, N Mohan, MRP Kurup, S Erkan, S Kaya, E Manoj Polyhedron 256, 116998 , 2024 2024 Citations: 5
A novel Salen-based dual channel sensor for easy and selective nanomolar detection of l-cysteine N Mohan, SS Sreejith, MRP Kurup New Journal of Chemistry 48 (6), 2584-2593 , 2024 2024 Citations: 1
Structural tuning effect to enhance the nonlinear optical response of salen type compounds N Mohan, SS Sreejith, PV Mohanan, MRP Kurup AIP Conference Proceedings 2783 (1), 050004 , 2023 2023
Emergent Catalytic Materials Towards CO 2 Reduction SS Sreejith, N Mohan, MRP Kurup Emerging Materials: Design, Characterization and Applications, 315-360 , 2022 2022
Copper (II) salen-based complexes as potential anticancer agents N Mohan, CV Vidhya, V Suni, JM Ameer, N Kasoju, PV Mohanan, ... New Journal of Chemistry 46 (26), 12540-12550 , 2022 2022 Citations: 24
Synthesis, crystal structure and ligand based catalytic activity of octahedral salen Schiff base Co (III) compounds N Mohan, SS Sreejith, R George, PV Mohanan, MRP Kurup Journal of Molecular Structure, 129779 , 2021 2021 Citations: 6
Facile synthesis, X-ray diffraction studies, photophysical properties and DFT-D based conformational analysis of octa and dodecacyanomethoxycalix [4] resorcinarenes AM Shebitha, SS Sreejith, PBS Mole, N Mohan, G Avudaiappan, K Hiba, ... Journal of Molecular Structure 1214, 128215 , 2020 2020 Citations: 2
Investigation on catecholase activity of salen Co (III) octahedral complexes N Mohan, SS Sreejith, MRP Kurup Polyhedron 173, 114129 , 2019 2019 Citations: 14
A modern approach for the sensing of aqueous Al (III) ion by Ni (II) Salen‐type Schiff base complexes N Mohan, S SS, PMS Begum, MRP Kurup Applied Organometallic Chemistry 33 (9), e5064 , 2019 2019 Citations: 10
A study of structural effects on linear and nonlinear response of bicompartmental Ni (II) Schiff base complexes N Mohan, S SS, V Kuttippurath, C Keloth, MRP Kurup Applied Organometallic Chemistry 33 (5), e4900 , 2019 2019 Citations: 9
Experimental and theoretical analysis of a rare nitrato bridged 3d-4f complex containing LaZn2 core synthesized from a Zn (II) metalloligand SS Sreejith, N Mohan, MRP Kurup Journal of Molecular Structure 1153, 85-95 , 2018 2018 Citations: 14
Dual responsive salen-type Schiff bases for the effective detection of L-arginine via a static quenching mechanism N Mohan, SS Sreejith, PMS Begum, MRP Kurup New Journal of Chemistry 42 (15), 13114-13121 , 2018 2018 Citations: 48
Experimental and theoretical studies on photoluminescent Zn (II) host complex with an open book structure: Implication on potential bioactivity and comparison with its ligand … SS Sreejith, N Mohan, MRP Kurup Polyhedron 135, 278-295 , 2017 2017 Citations: 25
Experimental and theoretical investigations on Pd (II) host-guest compound: Deciphering the structural and electronic features of a potential bioactive complex SS Sreejith, N Mohan, MRP Kurup Journal of Molecular Structure 1145, 170-183 , 2017 2017 Citations: 24
MOST CITED SCHOLAR PUBLICATIONS
Dual responsive salen-type Schiff bases for the effective detection of L-arginine via a static quenching mechanism N Mohan, SS Sreejith, PMS Begum, MRP Kurup New Journal of Chemistry 42 (15), 13114-13121 , 2018 2018 Citations: 48
Inclusion, pseudo-inclusion compounds and coordination polymer of Pd (II), Zn (II) and Cd (II) from salen-type Schiff base ligand with a 1, 3-diimino spacer group: Crystal … SS Sreejith, N Mohan, N Aiswarya, MRP Kurup Polyhedron 115, 180-192 , 2016 2016 Citations: 35
Experimental and theoretical studies on photoluminescent Zn (II) host complex with an open book structure: Implication on potential bioactivity and comparison with its ligand … SS Sreejith, N Mohan, MRP Kurup Polyhedron 135, 278-295 , 2017 2017 Citations: 25
Copper (II) salen-based complexes as potential anticancer agents N Mohan, CV Vidhya, V Suni, JM Ameer, N Kasoju, PV Mohanan, ... New Journal of Chemistry 46 (26), 12540-12550 , 2022 2022 Citations: 24
Experimental and theoretical investigations on Pd (II) host-guest compound: Deciphering the structural and electronic features of a potential bioactive complex SS Sreejith, N Mohan, MRP Kurup Journal of Molecular Structure 1145, 170-183 , 2017 2017 Citations: 24
Investigation on catecholase activity of salen Co (III) octahedral complexes N Mohan, SS Sreejith, MRP Kurup Polyhedron 173, 114129 , 2019 2019 Citations: 14
Experimental and theoretical analysis of a rare nitrato bridged 3d-4f complex containing LaZn2 core synthesized from a Zn (II) metalloligand SS Sreejith, N Mohan, MRP Kurup Journal of Molecular Structure 1153, 85-95 , 2018 2018 Citations: 14
Multi-faceted investigation of copper (II) chelates based on ONS donor thiosemicarbazone: crystal structures, spectral aspects, DNA binding, cytotoxicity and computational studies JM Jacob, N Mohan, M Sithambaresan, E Manoj, MRP Kurup Journal of Molecular Structure 1319, 139463 , 2025 2025 Citations: 12
A modern approach for the sensing of aqueous Al (III) ion by Ni (II) Salen‐type Schiff base complexes N Mohan, S SS, PMS Begum, MRP Kurup Applied Organometallic Chemistry 33 (9), e5064 , 2019 2019 Citations: 10
A study of structural effects on linear and nonlinear response of bicompartmental Ni (II) Schiff base complexes N Mohan, S SS, V Kuttippurath, C Keloth, MRP Kurup Applied Organometallic Chemistry 33 (5), e4900 , 2019 2019 Citations: 9
Water‐Encapsulated Ni (II) Salphen‐Type Host Complexes: Experimental and Theoretical Analysis of Potentially Bioactive Quasi‐Isostructural Polymorphs SS Sreekumar, N Mohan, MRP Kurup ChemistrySelect 2 (22), 6493-6502 , 2017 2017 Citations: 8
Synthesis, crystal structure and ligand based catalytic activity of octahedral salen Schiff base Co (III) compounds N Mohan, SS Sreejith, R George, PV Mohanan, MRP Kurup Journal of Molecular Structure, 129779 , 2021 2021 Citations: 6
(±)-trans-6, 6′-Diethoxy-2, 2′-[cyclohexane-1, 2-diylbis (nitrilomethanylylidene)] diphenol monohydrate N Mohan, SS Sreejith, M Sithambaresan, MRP Kurup Structure Reports 70 (2), o182-o183 , 2014 2014 Citations: 6
Mononuclear and binuclear dioxidomolybdenum (VI) chelates derived from a tridentate ONO donor aroylhydrazone: Spectral, structural, DFT and in silico biological investigations AA Aravindakshan, N Mohan, MRP Kurup, S Erkan, S Kaya, E Manoj Polyhedron 256, 116998 , 2024 2024 Citations: 5
Pyrazolyl-derived zinc (II) and cadmium (II) complexes: Synthesis, spectral characterization, single crystal insights, Hirshfeld surface analysis, and in silico DNA interaction … LK Suresh, PK Maniyampara, N Mohan, M Simi, K Gopal, MRP Kurup, ... Inorganic Chemistry Communications 168, 112811 , 2024 2024 Citations: 3
Bioactivity Modulation: Anionic Influence on Cu (II) Schiff Base Complexes JK Sebastian, SR Amrutha, NR Suja, N Mohan, SS Sreejith, ... Applied Organometallic Chemistry 39 (3), e7853 , 2025 2025 Citations: 2
Facile synthesis, X-ray diffraction studies, photophysical properties and DFT-D based conformational analysis of octa and dodecacyanomethoxycalix [4] resorcinarenes AM Shebitha, SS Sreejith, PBS Mole, N Mohan, G Avudaiappan, K Hiba, ... Journal of Molecular Structure 1214, 128215 , 2020 2020 Citations: 2
Mononuclear and trinuclear zinc (II) architectures derived from functionalized pyrazole-fenamic acid hybrids: Synthesis, structure, fluorescence, and bioactivity LK Suresh, N Mohan, M Sithambaresan, MRP Kurup Journal of Molecular Structure, 143844 , 2025 2025 Citations: 1
A novel Salen-based dual channel sensor for easy and selective nanomolar detection of l-cysteine N Mohan, SS Sreejith, MRP Kurup New Journal of Chemistry 48 (6), 2584-2593 , 2024 2024 Citations: 1
Copper salen-type complexes as protein-interactive anticancer agents: A molecular and experimental study N Mohan, SS Sreejith, MRP Kurup Journal of Molecular Structure, 144968 , 2025 2025