Dr. Nikhilesh Joardar

@mitwpu.edu.in

Assistant Professor, Department of Bioengineering
Dr. Vishwanath Karad MIT World Peace University

Dr. Nikhilesh Joardar


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https://researchid.co/nikhilesh.joardar
Dr. Nikhilesh Joardar, M.Sc., Ph.D. is an Assistant Professor in the Department of Bioengineering at Dr. Vishwanath D. Karad MIT-World Peace University, Pune. His research spans parasitology, host–pathogen interactions, immunology, and antiparasitic drug development. Dr. Joardar previously worked as a Postdoctoral Research Associate at the Department of Immunology & Microbiology, University of North Carolina at Chapel Hill and Department of Medicine (Division of Infectious Diseases) Washington University School of Medicine in St. Louis, contributing to studies on bacterial, parasitic infections and biomarker discovery. He did his PhD on antifilarial drug development and host-pathogen interaction from the Department of Zoology, Visva Bharati (An Institute of national importance). He has published extensively in leading journals, received multiple national research fellowships, and serves as an Associate Editor for Frontiers in Neglected Tropical Diseases and review editor in Frontiers i

EDUCATION

Postdoc: 2022-2025
Ph. D. : 2016-2021
M.Sc. 2014
B.Sc. 2012

RESEARCH, TEACHING, or OTHER INTERESTS

Immunology and Microbiology, Infectious Diseases, Parasitology, Biomedical Engineering
35

Scopus Publications

672

Scholar Citations

13

Scholar h-index

18

Scholar i10-index

Scopus Publications

RECENT SCHOLAR PUBLICATIONS

  • The gut microbiota shapes the human and murine breath volatilome
    AJ Hernandez-Leyva, AZ Berna, MH Bui, Y Liu, AL Rosen, MA Lint, ...
    Cell Metabolism , 2026
    2026
    Citations: 4
  • In silico assessment of cyanobacterial alkaloids as probable medications against SARS-CoV-2
    A Sen, HMKC Chanda, S Cheemanapalli, A Umamaheswari, J Rath, ...
    In Silico Research in Biomedicine 2, 100215 , 2026
    2026
  • Clinical trials unveiling the potential of phytochemicals across different diseases
    A Kundu, P Rooj, N Joardar, AK Sinha, A Sen
    Phytoceuticals in Food for Health and Wellness, 309-340 , 2026
    2026
  • In silico exploration and in vitro validation of the filarial thioredoxin reductase inhibitory activity of Scytonemin and its derivatives
    A Sen, V Dewaker, U Debnath, K Jana, J Rath, N Joardar, SP Sinha Babu
    Journal of Biomolecular Structure and Dynamics 43 (2), 890-902 , 2025
    2025
    Citations: 8
  • The breath volatilome is shaped by the gut microbiota
    AJ Hernandez-Leyva, AZ Berna, Y Liu, AL Rosen, MA Lint, SA Whiteside, ...
    medRxiv , 2024
    2024
    Citations: 5
  • An ethnopharmacological approach to evaluate antiparasitic and health-promoting abilities of Pueraria tuberosa (Willd.) DC. in livestock
    SK Mandal, N Mukherjee, AS Ray, S Hazra, S Saha, S Das, N Joardar, ...
    PLoS one 19 (7), e0305667 , 2024
    2024
    Citations: 4
  • Filarial thioredoxin reductase: a possible means to exterminate lymphatic filariasis.
    N Joardar, SPS Babu
    2022
    Citations: 1
  • Crude protein fraction with high thioredoxin reductase (TrxR) enzyme activity from filarial parasite Setaria cervi counters lipopolysaccharide (LPS)-induced …
    N Joardar, K Jana, SPS Babu
    Parasitology Research 121 (5), 1379-1388 , 2022
    2022
    Citations: 3
  • Anti-microfilarial Activities of Azadirachta indica (A. Juss.) Against Dirofilaria immitis in Dogs ( Canis familiaris )
    N Mukherjee, N Joardar, S Mukherjee, SP Sinha Babu
    Proceedings of the Zoological Society 75 (1), 127-133 , 2022
    2022
  • Effect of Senna plant on the mitochondrial activity of Hymenolepis diminuta
    B Ukil, N Joardar, SPS Babu, LM Lyndem
    Journal of Parasitic Diseases 46 (1), 139-151 , 2022
    2022
    Citations: 5
  • Filarial thioredoxin reductase exerts anti-inflammatory effects upon lipopolysaccharide induced inflammation in macrophages
    N Joardar, R Bhattacharya, S Halder, A Sen, SR Biswas, K Jana, ...
    International journal of biological macromolecules 193, 1379-1390 , 2021
    2021
    Citations: 10
  • Disruption of redox homeostasis with synchronized activation of apoptosis highlights the antifilarial efficacy of novel piperine derivatives: an in vitro mechanistic approach
    N Joardar, P Shit, S Halder, U Debnath, S Saha, AK Misra, K Jana, ...
    Free Radical Biology and Medicine 169, 343-360 , 2021
    2021
    Citations: 10
  • A review on the interactions between dendritic cells, filarial parasite and parasite‐derived molecules in regulating the host immune responses
    N Joardar, C Mondal, SP Sinha Babu
    Scandinavian Journal of Immunology 93 (4), e13001 , 2021
    2021
    Citations: 13
  • Inhibition of thioredoxin reductase (TrxR) triggers oxidative stress-induced apoptosis in filarial nematode Setaria cervi channelized through ASK-1-p38 mediated caspase activation
    N Joardar, A Sen, J Rath, SPS Babu
    Molecular and biochemical parasitology 242, 111364 , 2021
    2021
    Citations: 12
  • Nanopharmaceuticals to target antifilarials: administration of old age drugs in a novel way
    N Joardar, N Mukherjee, SPS Babu
    Applications of Nanobiotechnology for Neglected Tropical Diseases, 329-356 , 2021
    2021
    Citations: 3
  • Triggering the downstream apoptotic signal inside human parasitic organisms demonstrates a promising approach for anti-parasitic drug development: A mechanistic perspective
    N Joardar, N Mukherjee, S Halder, K Jana, SPS Babu
    Advances in Protein Chemistry and Structural Biology 125, 193-213 , 2021
    2021
    Citations: 4
  • Thiol antioxidant thioredoxin reductase: A prospective biochemical crossroads between anticancer and antiparasitic treatments of the modern era
    N Joardar, A Guevara-Flores, JJ Martinez-Gonzalez, SPS Babu
    International journal of biological macromolecules 165, 249-267 , 2020
    2020
    Citations: 28
  • Senna plant generates reactive oxygen species (ROS) and induces apoptosis in Hymenolepis diminuta
    S Roy, N Joardar, SPS Babu, LM Lyndem
    Molecular and biochemical parasitology 238, 111297 , 2020
    2020
    Citations: 15
  • Synthesis of Novel Glycosyl Carbamo (dithioperoxo) thioate Derivatives
    A Gucchait, S Ghosh, AK Misra
    Synthesis 52 (10), 1523-1530 , 2020
    2020
    Citations: 4
  • Polymer anchored gold nanoparticles: synthesis, characterization and antimicrobial activities
    SPSB Pranesh Chowdhury, Bishnupada Roy, Suprabhat Mukherjee, Niladri ...
    Journal Nanoscience & Nanotechnology-Asia 10 , 2020
    2020
    Citations: 9

MOST CITED SCHOLAR PUBLICATIONS

  • Gut microbes as future therapeutics in treating inflammatory and infectious diseases: lessons from recent findings
    S Mukherjee, N Joardar, S Sengupta, SPS Babu
    The Journal of nutritional biochemistry 61, 111-128 , 2018
    2018
    Citations: 145
  • Graphene oxide dispersed supramolecular hydrogel capped benign green silver nanoparticles for anticancer, antimicrobial, cell attachment and intracellular imaging applications
    D Ghosh, S Dhibar, A Dey, S Mukherjee, N Joardar, SPS Babu, B Dey
    Journal of Molecular Liquids 282, 1-12 , 2019
    2019
    Citations: 49
  • Chitosan biopolymer functionalized gold nanoparticles with controlled cytotoxicity and improved antifilarial efficacy
    P Chowdhury, B Roy, N Mukherjee, S Mukherjee, N Joardar, MK Mondal, ...
    Advanced Composites and Hybrid Materials 1 (3), 577-590 , 2018
    2018
    Citations: 47
  • Synthesis of smart graphene quantum dots: A benign biomaterial for prominent intracellular imaging and improvement of drug efficacy
    MK Mondal, S Mukherjee, N Joardar, D Roy, P Chowdhury, SPS Babu
    Applied Surface Science 495, 143562 , 2019
    2019
    Citations: 46
  • Aryl quinolinyl hydrazone derivatives as anti-inflammatory agents that inhibit TLR4 activation in the macrophages
    U Debnath, S Mukherjee, N Joardar, SPS Babu, K Jana, AK Misra
    European Journal of Pharmaceutical Sciences 134, 102-115 , 2019
    2019
    Citations: 43
  • Quinolone-fused cyclic sulfonamide as a novel benign antifilarial agent
    S Mukherjee, N Joardar, S Mondal, A Schiefer, A Hoerauf, K Pfarr, ...
    Scientific Reports 8 (1), 12073 , 2018
    2018
    Citations: 38
  • Development of novel anti-filarial agents using carbamo (dithioperoxo) thioate derivatives
    A Gucchait, N Joardar, PK Parida, P Roy, N Mukherjee, A Dutta, ...
    European Journal of Medicinal Chemistry 143, 598-610 , 2018
    2018
    Citations: 35
  • Polyphenol enriched ethanolic extract of Cajanus scarabaeoides (L.) Thouars exerts potential antifilarial activity by inducing oxidative stress and programmed cell death
    AS Ray, N Joardar, S Mukherjee, CH Rahaman, SP Sinha Babu
    Plos One 13 (12), 1-18 , 2018
    2018
    Citations: 29
  • Thiol antioxidant thioredoxin reductase: A prospective biochemical crossroads between anticancer and antiparasitic treatments of the modern era
    N Joardar, A Guevara-Flores, JJ Martinez-Gonzalez, SPS Babu
    International journal of biological macromolecules 165, 249-267 , 2020
    2020
    Citations: 28
  • A review on the druggability of a thiol-based enzymatic antioxidant thioredoxin reductase for treating filariasis and other parasitic infections
    N Joardar, SPS Babu
    International journal of biological macromolecules 142, 125-141 , 2020
    2020
    Citations: 22
  • Antifilarial activity of azadirachtin fuelled through reactive oxygen species induced apoptosis: a thorough molecular study on Setaria cervi
    N Mukherjee, N Joardar, SPS Babu
    Journal of Helminthology 93 (5), 519-528 , 2019
    2019
    Citations: 22
  • Thioredoxin reductase from the bovine filarial parasite Setaria cervi: Studies on its localization and optimization of the extraction
    N Joardar, S Mukherjee, SPS Babu
    International journal of biological macromolecules 107, 2375-2384 , 2018
    2018
    Citations: 20
  • Senna plant generates reactive oxygen species (ROS) and induces apoptosis in Hymenolepis diminuta
    S Roy, N Joardar, SPS Babu, LM Lyndem
    Molecular and biochemical parasitology 238, 111297 , 2020
    2020
    Citations: 15
  • A review on the interactions between dendritic cells, filarial parasite and parasite‐derived molecules in regulating the host immune responses
    N Joardar, C Mondal, SP Sinha Babu
    Scandinavian Journal of Immunology 93 (4), e13001 , 2021
    2021
    Citations: 13
  • Redox regulatory circuits as targets for therapeutic intervention of bancroftian filariasis: biochemical, molecular, and pharmacological perspectives
    S Mukherjee, N Joardar, SP Sinha Babu
    Oxidative stress in microbial diseases, 185-208 , 2019
    2019
    Citations: 13
  • Inhibition of thioredoxin reductase (TrxR) triggers oxidative stress-induced apoptosis in filarial nematode Setaria cervi channelized through ASK-1-p38 mediated caspase activation
    N Joardar, A Sen, J Rath, SPS Babu
    Molecular and biochemical parasitology 242, 111364 , 2021
    2021
    Citations: 12
  • Filarial thioredoxin reductase exerts anti-inflammatory effects upon lipopolysaccharide induced inflammation in macrophages
    N Joardar, R Bhattacharya, S Halder, A Sen, SR Biswas, K Jana, ...
    International journal of biological macromolecules 193, 1379-1390 , 2021
    2021
    Citations: 10
  • Disruption of redox homeostasis with synchronized activation of apoptosis highlights the antifilarial efficacy of novel piperine derivatives: an in vitro mechanistic approach
    N Joardar, P Shit, S Halder, U Debnath, S Saha, AK Misra, K Jana, ...
    Free Radical Biology and Medicine 169, 343-360 , 2021
    2021
    Citations: 10
  • Polymer anchored gold nanoparticles: synthesis, characterization and antimicrobial activities
    SPSB Pranesh Chowdhury, Bishnupada Roy, Suprabhat Mukherjee, Niladri ...
    Journal Nanoscience & Nanotechnology-Asia 10 , 2020
    2020
    Citations: 9
  • Exploring the homolog of a novel proinflammatory microfilarial sheath protein (MfP) of Wuchereria bancrofti in the adult-stage bovine filarial parasite Setaria cervi
    S Mukherjee, N Joardar, SPS Babu
    Journal of Helminthology , 2018
    2018
    Citations: 9