Software Reliability, Software Testing, Optimization, Medical Data Analysis, Accelerated Life Testing
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Scopus Publications
Scopus Publications
Software reliability modeling for fault detection and fault correction processes considering Burr Type X testing effort function Kaushal Kumar, Nesar Ahmad, Zubair Ahmad, Jitendra Kumar Frontiers in Applied Mathematics and Statistics, 2025 Software reliability analysis is vital for evaluating software quality, where reliability is the probability of failure operation of a system for a specified duration. Numerous SRGMs have been proposed, mainly based on the NHPP to enhance the reliability of software product. A key aspect of software reliability modeling involves the FDP and FCP, both of which are vital for understanding and predicting software performance. These models have evolved to consider dependencies between FD and FC, time delay effects, and testing effort consumption, thereby refining predictions and providing robust reliability estimates. In this paper, we first provide a comprehensive review of the last four decades of research on software reliability modeling, focusing on methods proposed for predicting software reliability through FDP and FCP. We then present the FDP and FCP for imperfect debugging considering BTXTEF. Two specific paired FDP and FCP models are proposed with BTXTEF. The proposed SRGM with BTXTEF contains some undetermined parameters. We use PSO to optimize these parameters on an actual dataset rather than using traditional estimation methods. We compare the performance of the proposed SRGM model, in relation to other existing models from the literature. The results reveal that the proposed SRGM with BTXTEF for FDP and FCP is highly effective and outperforms existing models.
Identification of Novel Diagnostic and Prognostic Gene Signature Biomarkers for Breast Cancer Using Artificial Intelligence and Machine Learning Assisted Transcriptomics Analysis Zeenat Mirza, Md Shahid Ansari, Md Shahid Iqbal, Nesar Ahmad, Nofe Alganmi, Haneen Banjar, Mohammed H. Al-Qahtani, Sajjad Karim Cancers, 2023 Background: Breast cancer (BC) is one of the most common female cancers. Clinical and histopathological information is collectively used for diagnosis, but is often not precise. We applied machine learning (ML) methods to identify the valuable gene signature model based on differentially expressed genes (DEGs) for BC diagnosis and prognosis. Methods: A cohort of 701 samples from 11 GEO BC microarray datasets was used for the identification of significant DEGs. Seven ML methods, including RFECV-LR, RFECV-SVM, LR-L1, SVC-L1, RF, and Extra-Trees were applied for gene reduction and the construction of a diagnostic model for cancer classification. Kaplan–Meier survival analysis was performed for prognostic signature construction. The potential biomarkers were confirmed via qRT-PCR and validated by another set of ML methods including GBDT, XGBoost, AdaBoost, KNN, and MLP. Results: We identified 355 DEGs and predicted BC-associated pathways, including kinetochore metaphase signaling, PTEN, senescence, and phagosome-formation pathways. A hub of 28 DEGs and a novel diagnostic nine-gene signature (COL10A, S100P, ADAMTS5, WISP1, COMP, CXCL10, LYVE1, COL11A1, and INHBA) were identified using stringent filter conditions. Similarly, a novel prognostic model consisting of eight-gene signatures (CCNE2, NUSAP1, TPX2, S100P, ITM2A, LIFR, TNXA, and ZBTB16) was also identified using disease-free survival and overall survival analysis. Gene signatures were validated by another set of ML methods. Finally, qRT-PCR results confirmed the expression of the identified gene signatures in BC. Conclusion: The ML approach helped construct novel diagnostic and prognostic models based on the expression profiling of BC. The identified nine-gene signature and eight-gene signatures showed excellent potential in BC diagnosis and prognosis, respectively.
Security and Privacy Technique in Big Data: A Review Proceedings of the 17th Indiacom 2023 10th International Conference on Computing for Sustainable Global Development Indiacom 2023, 2023
Testing Effort-based Software Reliability Growth Models: A Comprehensive Study Proceedings of the 17th Indiacom 2023 10th International Conference on Computing for Sustainable Global Development Indiacom 2023, 2023
Gene expression study of breast cancer using Welch Satterthwaite t-test, Kaplan-Meier estimator plot and Huber loss robust regression model Sajjad Karim, Md Shahid Iqbal, Nesar Ahmad, Md Shahid Ansari, Zeenat Mirza, Adnan Merdad, Saddig D. Jastaniah, Sudhir Kumar Journal of King Saud University Science, 2023 Breast Cancer (BC) is one of the deadliest diseases in women, causing thousands of deaths annually despite the advent of high-throughput genomic platforms in the recent past. Microarray-based gene expression profiling with different statistical methods have been extensively used to understand the disease at the molecular level. We plan to apply Welch Satterthwaite t-test, Kaplan-Meier estimator plot and Huber Loss robust regression model on microarray data to improve the analysis and find biomarkers for future diagnosis, prognosis, and treatment. We retrieved microarray data (GSE10810 dataset) of 31 breast tumor samples and 27 normal breast samples from Gene Expression Omnibus (GEO, NCBI). Welch Satterthwaite t-test was applied to identify the most statistically significant genes, Huber loss robust regression model was applied to investigate the existing mathematical relations between tumor and control variables, and Kaplan-Meier Plotter was used to confirm their association with overall metastatic relapse-free survival of BC patients. We identified 1837 differentially expressed genes, including 638 overexpressed (COL11A1, KIAA0101, S100P, GJB2, TOP2A, LINC01614, RRM2, INHBA, C15orf48 and CKS2) and 1199 under expressed (LEP, ADIPOQ, PLIN1, PCK1, PCOLCE2, ADH1B, LYVE1, FABP4, ABCA8, and CHRDL1) genes passing the threshold (fold change ± 2 and p value < 0.001). KM analysis revealed 12 out of 20 DEGs (log rank p value < 0.05) as potential prognostic and therapeutic biomarkers. Huber loss robust regression model was found to be one of the best performing algorithms for the mathematical relationship between the control and breast tumor samples with co-relation coefficient of 0.4398 and mean absolute error of 1.069 ± 0.020. In conclusion, with high mathematical confidence, we detected DEGs have high potential to be BC biomarkers using Welch t-test and Kaplan-Meier plot having minimum underlying assumptions.
An assessment of incorporating log-logistic testing effort into imperfect debugging delayed s-shaped software reliability growth model Nesar Ahmad, Aijaz Ahmad, Sheikh Umar Farooq International Journal of Software Innovation, 2021 Software reliability growth models (SRGM) are employed to aid us in predicting and estimating reliability in the software development process. Many SRGM proposed in the past claim to be effective over previous models. While some earlier research had raised concern regarding use of delayed S-shaped SRGM, researchers later indicated that the model performs well when appropriate testing-effort function (TEF) is used. This paper proposes and evaluates an approach to incorporate the log-logistic (LL) testing-effort function into delayed S-shaped SRGMs with imperfect debugging based on non-homogeneous Poisson process (NHPP). The model parameters are estimated by weighted least square estimation (WLSE) and maximum likelihood estimation (MLE) methods. The experimental results obtained after applying the model on real data sets and statistical methods for analysis are presented. The results obtained suggest that performance of the proposed model is better than the other existing models. The authors can conclude that the log-logistic TEF is appropriate for incorporating into delayed S-shaped software reliability growth models.
Parametric Software Reliability Growth Model with Testing Effort: A Review Md Zubair Ahmad, N. Ahmad 2021 International Conference on Computational Performance Evaluation Compe 2021, 2021 In modern society, the importance of software system is growing rapidly. Therefore, quality, reliability, and user fulfillment are the major goals for software development institutions. Software reliability modeling plays an major part in the evaluation of software reliability. In this paper, we present the literature survey during the past forty years of software reliability growth model (SRGM) proposed by researchers. This paper brings all together the theory, practice, and models required to effectively access software reliability. We also review the testing effort functions (TEFs) incorporated into SRGM proposed by various authors to improve software reliability. We discuss and present the classification of software reliability growth models. This paper helps the researchers to have a clear view of parametric software reliability growth modeling. Finally, we conclude the paper by highlighting the contributions and possible research directions.
Software reliability growth modeling with burr type XII using fuzzy logic Seema Rani, N. Ahmad Proceedings of the 2020 International Conference on Computing Communication and Security Icccs 2020, 2020 Software reliability modeling is used to detect and correct software errors. The accurate reliability prediction is the main challenges of software engineers. It is also an important task to develop software with high reliability. The precise quantification of parameter is not always possible, nor is it always necessary. When the values of parameters and variables cannot be precisely specified, they are said to be uncertain or fuzzy. To make the model more reliable, developer need to introduce some degree of uncertainty in the models. In this paper we discuss software reliability growth model considering Burr Type-XII testing effort function and fuzzy logic. Further, we consider the certain uncertainty level that involves in the testing-effort (TE) consumption and reliability parameters. We estimate the TE and reliability parameters of software reliability growth model (SRGM) by using method of least square and maximum likelihood techniques. Several reliability measures are calculated at different level of uncertainty. We compare the results with existing models from the literature. We also calculate cost of software under fuzzy environment and the results are compared with other published work.
Considering Burr Type X Testing Effort into S-shaped Software Reliability Modeling and Application 12th Indiacom 5th International Conference on Computing for Sustainable Global Development Indiacom 2018, 2018
Analysis of Incorporating New Modified Weibull Testing-effort into Delayed S-shaped Software Reliability Growth Model with imperfect debugging 11th Indiacom 4th International Conference on Computing for Sustainable Global Development Indiacom 2017, 2017
Analysis of software fault detection and correction process models with Burr Type XII testing-effort Proceedings of the 10th Indiacom 2016 3rd International Conference on Computing for Sustainable Global Development Indiacom 2016, 2016
Optimal compromise allocation in two-stage and stratified two-stage sampling designs for multivariate study Journal of Applied Statistical Science, 2012
Design of accelerated life tests for periodic inspection with Burr Type III distributions: Models, assumptions and applications Progress in Applied Statistics Research, 2009
Analysis of a software reliability growth models: The case of log-logistic test-effort function Proceedings of the IASTED International Conference on Modelling and Simulation, 2006