Marcos Leoni Gazarini

@unifesp.br

Professor, Department of Biosciences
Federal University of Sao Paulo

Marcos Leoni Gazarini


               Download Compact PDF  
https://researchid.co/mgazarini

RESEARCH, TEACHING, or OTHER INTERESTS

Cell Biology, Biochemistry, Genetics and Molecular Biology, Parasitology, Drug Discovery
47

Scopus Publications

1798

Scholar Citations

23

Scholar h-index

36

Scholar i10-index

Scopus Publications

RECENT SCHOLAR PUBLICATIONS

  • Evaluation of the Activity of 4-Quinolones against Multi-Life Stages of Plasmodium spp.
    Y Annunciato, EM Da Silva, JE Araújo, LN Martinez, S Santana, ...
    ACS omega 10 (45), 54850-54863 , 2025
    2025
    Citations: 1
  • Fluorescent Marinoquinoline Derivative as Inhibitors of Plasmodium falciparum
    P Santos Barbosa, GE Souza, SEC Maluf, V Bonatto, CS Moura, ...
    2025
  • Fluorescent Marinoquinoline Derivative as Inhibitors of Plasmodium falciparum : SAR Analysis, Mode of Action and In Vivo Studies
    P Santos Barbosa, GE Souza, SEC Maluf, V Bonatto, CS Moura, ...
    Journal of Medicinal Chemistry 68 (20), 21120-21143 , 2025
    2025
    Citations: 1
  • Captopril reduces liver cytotoxicity in a murine model of Plasmodium chabaudi infection.
    PD de Souza Ventura, DV de Souza, ACC Aguiar, CPF Carvalho, ...
    Environmental Toxicology and Pharmacology, 104801 , 2025
    2025
  • Indole-2-carboxamides Optimization for Antiplasmodial Activity
    M Kumar, A Ahmad, ACC Aguiar, SEC Maluf, A Shamim, M Ferrer, ...
    ACS Bio & Med Chem Au 5 (5), 821-839 , 2025
    2025
    Citations: 3
  • Mode-of-action investigation of a new generation of acridine/acridonebased antimalarials
    SEC Maluf, GR Mendes, IMR Moura, GE Souza, V Bonatto, GS Oliveira, ...
    Annals , 2025
    2025
  • Antimalarial potential of a marine sponge Tedania Ignis against plasmodium falciparum
    CS Moura, Y Annunciato, TBV Dantas, WGM Júnior, LRG Silva, ...
    2024
    Citations: 1
  • Effect of Kinins on the Hepatic Oxidative Stress in Mice Treated with a Methionine-Choline Deficient Diet
    MS Thomaz, MN Sertorio, ML Gazarini, DA Ribeiro, LP Pisani, ...
    Biomedicines 11 (8), 2199 , 2023
    2023
    Citations: 1
  • Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues
    WA Cortopassi, E Gunderson, Y Annunciato, AES Silva, ...
    International Journal for Parasitology: Drugs and Drug Resistance 20, 121-128 , 2022
    2022
    Citations: 9
  • Synthesis, Structure–Activity Relationships, and Parasitological Profiling of Brussonol Derivatives as New Plasmodium falciparum Inhibitors
    CS Barbosa, A Ahmad, SEC Maluf, IMR Moura, GE Souza, GAH Guerra, ...
    Pharmaceuticals 15 (7), 814 , 2022
    2022
    Citations: 5
  • Early decrease in Cx36 is associated with increased cell adhesion molecules (CAMs) junctional content in mouse pancreatic islets after short-term high-fat diet feeding
    C Martinez, DA Maschio, CC de Fontes, EC Vanzela, ID Benfato, ...
    Annals of Anatomy-Anatomischer Anzeiger 241, 151891 , 2022
    2022
    Citations: 2
  • South American rattlesnake cationic polypeptide crotamine trafficking dynamic in Plasmodium falciparum-infected erythrocytes: Pharmacological inhibitors, parasite cycle and …
    SEC Maluf, MAF Hayashi, JD Campeiro, EB Oliveira, ML Gazarini, ...
    Toxicon 208, 47-52 , 2022
    2022
    Citations: 6
  • Chondroitin sulfate protects the liver in an experimental model of extra-hepatic cholestasis induced by common bile duct ligation
    PLR Guedes, CPF Carvalho, AAF Carbonel, MJ Simões, MY Icimoto, ...
    Molecules 27 (3), 654 , 2022
    2022
    Citations: 11
  • Effect of Brussonol on the calcium homeostasis in Plasmodium falciparum
    CS Barbosa, SEC Maluf, A Ahmad, IMR Moura, GE Souza, ACB Burtoloso, ...
    Anais eletrônicos , 2022
    2022
  • Dual quinoline-hybrid compounds with antimalarial activity against Plasmodium falciparum parasites
    GJ da Silva Neto, LR Silva, RJM de Omena, ACC Aguiar, Y Annunciato, ...
    New Journal of Chemistry 46 (14), 6502-6518 , 2022
    2022
    Citations: 19
  • Overexpression of Plasmodium falciparum M1 Aminopeptidase Promotes an Increase in Intracellular Proteolysis and Modifies the Asexual Erythrocytic Cycle …
    CC Hoff, MF Azevedo, AB Thurler, SEC Maluf, PMS Melo, MA Del Rivero, ...
    Pathogens 10 (11), 1452 , 2021
    2021
    Citations: 5
  • Metabolites from marine sponges and their potential to treat malarial protozoan parasites infection: A systematic review
    ACC Aguiar, JR Parisi, RN Granito, LRF de Sousa, ACM Renno, ...
    Marine drugs 19 (3), 134 , 2021
    2021
    Citations: 25
  • Overexpression of Plasmodium falciparum M1 Aminopeptidase Promotes an Increase in Intracellular Proteolysis and Modifies the Asexual Erythrocytic Cycle Development. Pathogens …
    CC Hoff, MF Azevedo, AB Thurler, SEC Maluf, PMS Melo, MA del Rivero, ...
    s Note: MDPI stays neutral with regard to jurisdictional claims in published … , 2021
    2021
  • Human plasma plasminogen internalization route in Plasmodium falciparum -infected erythrocytes
    S El Chamy Maluf, MY Icimoto, PMS Melo, A Budu, R Coimbra, ...
    Malaria Journal 19 (1), 302 , 2020
    2020
    Citations: 5
  • Decreased nuclear distribution nudE-like 1 enzyme activity in an animal model with dysfunctional disrupted-in-schizophrenia 1 signaling featuring aberrant neurodevelopment and …
    JV Nani, MC Fonseca, SA Engi, MG Perillo, CSB Dias, ML Gazarini, ...
    Journal of Psychopharmacology 34 (4), 467-477 , 2020
    2020
    Citations: 20

MOST CITED SCHOLAR PUBLICATIONS

  • Calcium-dependent modulation by melatonin of the circadian rhythm in malarial parasites.
    CT Hotta, ML Gazarini, FH Beraldo, FP Varotti, C Lopes, RP Markus, ...
    Nature cell biology 2 (7), 466-468 , 2000
    2000
    Citations: 228
  • The Plasmodium falciparum STEVOR Multigene Family Mediates Antigenic Variation of the Infected Erythrocyte
    M Niang, X Yan Yam, PR Preiser
    PLoS pathogens 5 (2), e1000307 , 2009
    2009
    Citations: 194
  • Calcium signaling in a low calcium environment: how the intracellular malaria parasite solves the problem
    ML Gazarini, AP Thomas, T Pozzan, CRS Garcia
    The Journal of cell biology 161 (1), 103-110 , 2003
    2003
    Citations: 193
  • Carotenoid biosynthesis in intraerythrocytic stages of Plasmodium falciparum
    R Tonhosolo, LD Fabio, VV de Rosso, ML Gazarini, MY Matsumura, ...
    Journal of Biological Chemistry 284 (15), 9974-9985 , 2009
    2009
    Citations: 106
  • The malaria parasite mitochondrion senses cytosolic Ca2+ fluctuations
    ML Gazarini, CRS Garcia
    Biochemical and biophysical research communications 321 (1), 138-144 , 2004
    2004
    Citations: 80
  • Plasmodium falciparum malaria parasites display a THG-sensitive Ca2+ pool
    FP Varotti, FH Beraldo, ML Gazarini, CRS Garcia
    Cell Calcium 33 (2), 137-144 , 2003
    2003
    Citations: 78
  • Inhibition of malaria parasite Plasmodium falciparum development by crotamine, a cell penetrating peptide from the snake venom
    SEC Maluf, C Dal Mas, EB Oliveira, PM Melo, AK Carmona, ML Gazarini, ...
    Peptides 78, 11-16 , 2016
    2016
    Citations: 76
  • Evidence of lysosomal membrane permeabilization in mucopolysaccharidosis type I: rupture of calcium and proton homeostasis
    VG Pereira, ML Gazarini, LC Rodrigues, FH Da Silva, SW Han, ...
    Journal of cellular physiology 223 (2), 335-342 , 2010
    2010
    Citations: 68
  • Melatonin triggers PKA activation in the rodent malaria parasite Plasmodium chabaudi
    ML Gazarini, FH Beraldo, FM Almeida, M Bootman, AM Da Silva, ...
    Journal of Pineal Research 50 (1), 64-70 , 2011
    2011
    Citations: 53
  • Sleep deprivation alters gene expression and antioxidant enzyme activity in mice splenocytes
    L Lungato, MS Marques, VG Pereira, S Hix, ML Gazarini, S Tufik, ...
    Scandinavian journal of immunology 77 (3), 195-199 , 2013
    2013
    Citations: 49
  • Cysteine-protease activity elicited by Ca2+ stimulus in Plasmodium
    SL Farias, ML Gazarini, RL Melo, IY Hirata, MA Juliano, L Juliano, ...
    Molecular and biochemical parasitology 141 (1), 71-79 , 2005
    2005
    Citations: 48
  • Human malaria parasites display a receptor for activated C kinase ortholog
    L Madeira, R DeMarco, ML Gazarini, S Verjovski-Almeida, CRS Garcia
    Biochemical and biophysical research communications 306 (4), 995-1001 , 2003
    2003
    Citations: 44
  • Treatment of Plasmodium chabaudi Parasites with Curcumin in Combination with Antimalarial Drugs: Drug Interactions and Implications on the Ubiquitin …
    Z Neto, M Machado, A Lindeza, V do Rosário, ML Gazarini, D Lopes
    Journal of Parasitology Research 2013 (1), 429736 , 2013
    2013
    Citations: 37
  • Hypervalent organotellurium compounds as inhibitors of P. falciparum calcium-dependent cysteine proteases
    SEC Maluf, PMS Melo, FP Varotti, ML Gazarini, RLOR Cunha, ...
    Parasitology international 65 (1), 20-22 , 2016
    2016
    Citations: 36
  • Interruption of the blood-stage cycle of the malaria parasite, Plasmodium chabaudi, by protein tyrosine kinase inhibitors
    ML Gazarini, CRS Garcia
    Brazilian journal of medical and biological research 36, 1465-1469 , 2003
    2003
    Citations: 35
  • KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library
    J González-Bacerio, SEC Maluf, Y Méndez, I Pascual, I Florent, PMS Melo, ...
    Bioorganic & medicinal chemistry 25 (17), 4628-4636 , 2017
    2017
    Citations: 33
  • Intracellular proteolysis of kininogen by malaria parasites promotes release of active kinins
    P Bagnaresi, NMT Barros, DM Assis, PMS Melo, RG Fonseca, MA Juliano, ...
    Malaria journal 11 (1), 156 , 2012
    2012
    Citations: 33
  • Antimalarial drugs disrupt ion homeostasis in malarial parasites
    ML Gazarini, CAO Sigolo, RP Markus, AP Thomas, CRS Garcia
    Memorias do Instituto Oswaldo Cruz 102, 329-334 , 2007
    2007
    Citations: 33
  • Paradoxical sleep deprivation impairs mouse survival after infection with malaria parasites
    L Lungato, ML Gazarini, EJ Paredes-Gamero, S Tufik, V D’Almeida
    Malaria journal 14 (1), 183 , 2015
    2015
    Citations: 28
  • Inhibition of Plasmodium falciparum cysteine proteases by the sugarcane cystatin CaneCPI-4
    PMS Melo, SEC Maluf, MF Azevedo, T Paschoalin, A Budu, P Bagnaresi, ...
    Parasitology international 67 (2), 233-236 , 2018
    2018
    Citations: 26