Biochemistry (medical), Public Health, Environmental and Occupational Health, Clinical Biochemistry, Endocrinology, Diabetes and Metabolism
101
Scopus Publications
Scopus Publications
Timing of Prophylactic Intrapartum Azithromycin Administration and Efficacy in Prevention of Maternal and Infant Infections: A Secondary Analysis of a Randomized Controlled Trial Rupsa C. Boelig, Avinash Kavi, Janet L. Moore, Denise C. Babineau, Mrityunjay C. Metgud, Manjunath S. Somannavar, Shivaprasad S. Goudar, Richard J. Derman, Shiyam Sunder Tikmani, Sarah Saleem, Robert L. Goldenberg, Adrien L. Lokangaka, Antoinette K. Tshefu, Melissa S. Bauserman, Musaku Mwenechanya, Elwyn Chomba, Manolo Mazariegos, Lester Figueroa, Nancy F. Krebs, Paul Nyongesa, Fabian Esamai, Sherri Bucher, Archana B. Patel, Patricia L. Hibberd, William A. Petri, Sk Masum Billah, Rashidul Haque, Marion Koso‐Thomas, Elizabeth M. McClure, Waldemar A. Carlo, Alan T. N. Tita, and BJOG an International Journal of Obstetrics and Gynaecology, 2026 Objective A multi‐centre international trial (A‐PLUS), demonstrated that a single dose of 2 g oral azithromycin in labour reduced the risk of maternal sepsis or death, but not neonatal mortality. We aimed to determine whether the efficacy of azithromycin in prevention of any maternal infection or neonatal infection varied by time interval from azithromycin administration to delivery. Design This is a secondary analysis of a randomized controlled trial. Setting Multi‐centre international randomized controlled trial. Population Pregnant patients ≥ 28 weeks gestation (singleton or multiple gestation) presenting in labour for planned vaginal delivery. Outcomes The primary outcome for this secondary analysis was maternal infection and the secondary outcome was any neonatal infection. Methods The estimated relative risks (and 95% confidence interval) of any maternal or neonatal infection comparing azithromycin to placebo were obtained by fitting a Poisson model adjusting for site, treatment arm, hours between drug administration and delivery (as continuous measure, and ≤ 12 or > 12 h for maternal and ≤ 9 or > 9 h for neonatal), and the two‐way interaction between treatment arm and hours between drug administration and delivery. Results Included in the analysis were n = 14 569 randomized to azithromycin and n = 14 667 to placebo. There was no evidence that the benefit of azithromycin on reducing the risk of any maternal infection varied by time from dose to delivery (RR 0.71 (0.64–0.79) and RR 0.71 (0.54–0.94) for ≤ 12 and > 12 h respectively, interaction p = 0.987), although there was an observed interaction in Sub‐Saharan Africa subgroup with reduced risk observed with administration > 12 vs. ≤ 12 (RR 0.21 (0.08–0.54) vs. RR 0.52 (0.41–0.66), interaction p = 0.03). There was no benefit observed in prevention of infant infection regardless of time from dose to delivery (≤ 9 or > 9 h) (RR 1.00 (0.95–1.06) and RR 1.01 (0.88–1.15) interaction p = 0.997). Conclusion The benefit observed with a single intrapartum dose of azithromycin for prevention of any maternal infection in the setting of planned vaginal delivery was not observed to vary by time interval from azithromycin administration to delivery, although in some populations there may be greater benefit with delivery > 12 h from administration. Pregnant patients presenting for planned vaginal birth benefit from a single dose of 2 g azithromycin regardless of how soon delivery is anticipated.
Impact of prophylactic oral azithromycin during labor on Azithromycin Resistance (AMR) in nasal Staphylococcus aureus and Streptococcus pneumoniae in women and infants in the multicountry Azithromycin Prevention in Labor Use Study (A-PLUS) Patricia L. Hibberd, Jean H. Kim, Marissa Trotta, Sixto M. Leal, Anna Aceituno, Doyle V. Ward, Archana Patel, Akila Subramaniam, Waldemar A. Carlo, Imran Ahmed, Sarah Saleem, Sk Masum Billah, Rashidun Haque, Manolo Mazariegos, Fabian Esamai, Manjunath S. Somannavar, Shivaprasad S. Goudar, Elwyn Chomba, Muska Mwenchanya, Adrien Lokangaka, Antoinette Tshefu, Robert L. Goldenberg, Melissa Bauserman, Nancy F. Krebs, Sherri Bucher, Richard J. Derman, William A. Petri, Marion Koso-Thomas, Denise C. Babineau, Elizabeth M. McClure, Alan T. N. Tita Plos One, 2026 Background Prophylactic oral azithromycin vs. placebo reduced maternal, but not neonatal, mortality/sepsis in the A-PLUS Randomized Trial. While prophylactic intrapartum azithromycin reduces maternal mortality/sepsis, it may promote antimicrobial resistance (AMR) in commensal bacteria,. Methods Randomly selected women and their infants participating in A-PLUS were enrolled in a longitudinal cross-sectional sub-study to assess the presence of azithromycin resistance in selected bacteria in nasal cultures. Staphylococcus aureus and Streptococcus pneumoniae were cultured on selective agar, then azithromycin-containing agar to select for azithromycin resistant bacteria, identified biochemically. Azithromycin susceptibility was assessed by E-test. Nasal cultures were collected from women and infants between August 11, 2021 and September 18, 2023 during labor/day 1, day 7, 6 weeks, and 3, 6 and 12 months after delivery. Results The study enrolled 911 women and 915 liveborn infants at 8 sites in 7 countries. Azithromycin resistance in S aureus was higher and azithromycin susceptibility was lower in women receiving azithromycin compared with those receiving placebo on day 7 (P < 0.001), 6 weeks (P < 0.001) and 3 months (P = 0.009) after delivery. Azithromycin resistance in S aureus was also higher and azithromycin susceptibility was lower 6 weeks after delivery (P < 0.001) in infants born to women receiving azithromycin, Azithromycin resistance in S. pneumoniae was too sparse to interpret. Conclusions There was an increase in prevalence of azithromycin resistance (or reduction in azithromycin susceptibility) in commensal nasal S. aureus between day 7, 6 weeks and 3 months in women exposed to azithromycin vs. placebo and only at 6 weeks in infants exposed to azithromycin vs. placebo. These differences between the azithromycin and placebo groups were no longer detected at 6 and 12 months post-partum in the women and after 6 weeks through 12 months in the infants.
Maternal proinflammatory cytokines and risk of stillbirth in women with pregnancy induced hypertensive disorders: A case–control study Sanyukta Patil, Manjunath S. Somannavar, Deepthy M. Sadanandan, Elizabeth M. McClure, Shivaprasad S. Goudar, Robert L. Goldenberg International Journal of Gynecology and Obstetrics, 2026 Objectives Stillbirth, often a consequence of pregnancies complicated by disorders such as gestational hypertension, is a condition insufficiently addressed in resource‐limited countries. Developing new methods for early detection and management of gestational hypertension can help reduce stillbirths and associated adverse pregnancy outcomes by enabling timely interventions for high‐risk pregnancies. As cytokines are implicated in hypertension, we proposed to evaluate the association of tumor necrosis factor alpha (TNF‐α) and interleukin‐6 (IL‐6) with stillbirths among women affected by pregnancy‐induced hypertensive disorders. Methods Our case–control study constituted a total of 150 pre‐delivery samples: 50 of them from women who experienced stillbirths were taken as cases, 50 from women who had preterm livebirths were taken as preterm controls, and 50 from those who had a term livebirth were taken as term controls. These samples were selected through computer‐generated random selection from the overall population. The cytokine profile in maternal serum was measured using sandwich ELISA. Results The TNF‐α findings revealed statistically significant differences between the stillbirths (median [ Q 1 , Q 3 ]: 349 [168, 415]), preterm livebirths (median [ Q 1 , Q 3 ]: 223 [120, 384]), and term livebirths (median [ Q 1 , Q 3 ]: 221 [100, 311]) ( P = 0.02). Conversely, results obtained for IL‐6 demonstrated statistically significant differences between the stillbirths (median [ Q 1 , Q 3 ]: 117 [20, 220]) and preterm controls (median [ Q 1 , Q 3 ]: 22 [17, 63]) ( P = 0.001). However, no statistically significant difference was observed between the stillbirths and the term controls (median [ Q 1, Q 3]: 63 [28, 127]). Conclusion Tumor necrosis factor alpha was found to be strongly associated with risk of stillbirth, whereas IL‐6 showed a moderate association.
Maternal circulating sFlt-1/placental growth factor is a biomarker of fetal death associated with placental lesions of maternal vascular malperfusion Tinnakorn Chaiworapongsa, Roberto Romero, Elizabeth M. McClure, Shivaprasad Goudar, Manjunath Somannavar, Shiyam Sunder Tikmani, Sarah Saleem, Najia Ghanchi, Imran Ahmed, Afia Zafar, Sanyukta Patil, Sunilkumar BK, Yogeshkumar S, Jean Kim, Janet Moore, Arun Meyyazhagan, Awoniyi Awonuga, Dereje Gudicha, Adi L. Tarca, Robert L. Goldenberg Journal of Perinatal Medicine, 2026 Objectives Fetal death is a major pregnancy complication, with rates of 5.5 per 1,000 births in the United States and substantially higher in India (24.7/1,000) and Pakistan (44.5/1,000). Maternal vascular malperfusion (MVM) is the most frequent placental lesion associated with fetal death, occurring in 58 % of fetal deaths and 31 % of preterm neonatal deaths in South Asia. Angiogenic imbalance, characterized by a low placental growth factor (PlGF) to soluble fms-like tyrosine kinase-1 (sFlt-1) ratio, has been associated with MVM and fetal death in high-income countries. We examined whether maternal serum concentrations of PlGF, sFlt-1, and their ratio differ between mothers with and without MVM among stillbirths and preterm neonatal deaths in India and Pakistan. Methods This retrospective cohort analysis used data from the PURPOSe study (Project to Understand and Research Preterm Pregnancy Outcomes and Stillbirths in South Asia). Maternal blood was collected at delivery, and placental histopathology was classified according to the Amsterdam criteria. Serum PlGF and sFlt-1 were measured using Elecsys ® immunoassays, with analyses stratified by gestational age. Results Placental MVM was present in 44–57 % of stillbirths and 31–38 % of preterm neonatal deaths. Between 28 and 36 weeks, women with MVM had significantly lower PlGF and higher sFlt-1 and sFlt-1/PlGF ratios (p<0.001). A tenfold decrease in PlGF or increase in the ratio was associated with MVM (OR 0.5 and 1.7, respectively). Conclusions The maternal sFlt-1/PlGF ratio identifies pregnancies with fetal or neonatal death associated with placental MVM, particularly between 28 and 36 weeks’ gestation.
Developing a Co-Designed Strategy to Improve Labor Monitoring and Management in India Using the World Health Organization Labour Care Guide: A Mixed-Methods Formative Study Elizabeth Armari, Sunil S. Vernekar, Yeshita Pujar, Veronica Pingray, Fernando Althabe, Luz Gibbons, Mabel Berrueta, Alvaro Ciganda, Rocio Rodriguez, Jayashree Ashok Kumar, Shruti Bhavi Patil, Aravind Karinagannanavar, Raveendra R. Anteen, Pavithra M. R., Savitri Bendigeri, Shukla Shetty, B. Latha, Megha H. M., Suman S. Gaddi, Shaila Chikkagowdra, Bellara Raghavendra, Caroline S. E. Homer, Manjunath Somannavar, Shivaprasad S. Goudar, Joshua P. Vogel Birth, 2026 Introduction Nearly half of all perinatal deaths occur during the intrapartum period due to inadequate labor monitoring and intervention. The partograph, a paper‐based labor monitoring tool, can assist providers in recognizing and acting on early signs of fetal–maternal distress if used effectively. In 2020, the World Health Organization (WHO) developed a “next generation” partograph called the Labour Care Guide. There is limited evidence of how to optimize the use and impact of this new tool. This study describes the development of a co‐designed LCG implementation strategy in Karnataka, India. Methods A targeted literature review, primary research across four public maternity hospitals (provider survey and facility assessment), and a 2‐day co‐design workshop with stakeholders were conducted. Findings were mapped to six target behaviors using the Theoretical Domains Framework (TDF) and the Capability, Opportunity, and Motivation‐Behavior (COM‐B) model to identify potential barriers and facilitators to LCG use. Consultations with local stakeholders explored these factors, and a 1‐week pilot informed final refinements of the strategy. Results The LCG implementation strategy comprised an evidence‐based provider training program centered on “low dose, high frequency” principles, and monthly audit and feedback cycles, which in turn, relies on an enabling practice environment (supportive national policy frameworks, facility‐level guidelines, external partnerships, senior support, defining provider roles and expectations and adequate equipment and resources) to support its implementation. Conclusion Effective use of the LCG needs a robust, context‐sensitive implementation strategy. We present the first evidence‐based, co‐designed LCG implementation strategy which can be used to support LCG dissemination and uptake.
A Multicountry Analysis of Maternal Selenium Status in Pregnancy and Lactation and Infant Birth Outcomes: Findings from the Women First Maternal Preconception Study Stephanie P Gilley, Jamie L Westcott, Jennifer F Kemp, Julie M Long, K Michael Hambidge, Kartik Shankar, Nancy F Krebs, Sumera Aziz Ali, Abhik Das, Richard J Derman Lester Figueroa, Ana Garcés, Robert L Goldenberg, Shivaprasad Goudar, Elizabeth M McClure, Sarah Saleem, Manjunath S Somannavar Journal of Nutrition, 2026 BACKGROUND: Maternal selenium deficiency is hypothesized to contribute to risk of adverse outcomes including low birth weight and prematurity, possibly through its role as an antioxidant and/or in thyroid hormone function. OBJECTIVES: We assessed relationships between maternal selenium concentrations during pregnancy with offspring outcomes including birth measurements, low birth weight (<2500 g), prematurity (<37 wk), and small for gestational age (birth weight <10th percentile for gestational age). METHODS: This was a secondary analysis of the Women First Trial (NCT01883193), a randomized controlled study investigating the effect of small-quantity lipid-based nutrition supplement (sqLNS) with 130 μg selenium on fetal growth. sqLNS was started ≥3 mo prior to conception, around 12 wk of gestation, or not at all in women in Guatemala, India, and Pakistan. At 12 and 34 wk of gestation and 3 mo postpartum, maternal serum selenium was measured by inductively coupled plasma mass spectrometry (n = 145-325 per timepoint per site). We used generalized linear models adjusted for study arm, study site, and markers of inflammation to test for associations between maternal selenium status and offspring outcomes including birth anthropometry. RESULTS: Mean selenium concentrations decreased over the course of pregnancy and were lowest 3 mo postpartum. Selenium was lowest in Pakistan and did not increase with maternal supplementation. Across all sites, we found no significant associations between maternal selenium at 12 and 34 wk with birth weight- length-, or head circumference-for-age z-scores. There were also no associations with low birth weight, small for gestational age, or prematurity. CONCLUSIONS: Maternal selenium supplementation did not impact serum concentrations, suggesting that supplementation may not overcome the impact of low intake and the high demands of pregnancy and early lactation. Larger studies in high-risk regions are needed to further clarify the relationship between maternal selenium deficiency and infant outcomes. This trial was registered at clinicaltrials.gov as NCT01883193 (registered 18 June 2013).
Women with moderate anaemia prior to conception benefited most from nutrition interventions: a secondary analysis of the Women First preconception maternal nutrition trial Sumera Aziz Ali, Ka Kahe, Jeanine M Genkinger, Linda Valeri, Sarah Saleem, Saleem Jessani, Robert L Goldenberg, Jamie Westcott, Jennifer Kemp, Ana Garces, Lester Figueroa, Shivaprasad S Goudar, Sangappa M Dhaded, Richard Derman, Antoinette Tshefu Kitoto, Adrien Lokangaka, Melissa Bauserman, Elizabeth M McClure, Marion Koso-Thomas, Louise Kuhn, Nancy F Krebs BMJ Global Health, 2026 Introduction The Women First (WF) Preconception Maternal Nutrition trial found greater benefits of small-quantity lipid-based nutrient supplements (SQ-LNS) for intrauterine growth among anaemic versus non-anaemic women at preconception. We investigated whether the benefits of SQ-LNS in improving markers of intrauterine growth occurred evenly across the mild to moderate spectrum of pre-pregnancy anaemia. Methods We analysed WF data (n=2443 maternal-newborn dyads) from Pakistan, India, Guatemala and the Democratic Republic of Congo. Women received SQ-LNS either ≥3 months preconception through pregnancy (Arm 1); starting in the late first trimester (Arm 2); or not at all (Arm 3: control), with all supplementations discontinued at delivery. The outcomes were infant weight, length and head circumference measured within 48 hours of birth, expressed as Z-scores. For each site, adjusted mean differences in the Z-scores were computed across six pre-pregnancy haemoglobin (Hb) categories (80–89, 90–99, 100–109, 110–119, 120–129, and ≥130 g/L) and pooled using meta-analysis. Results The effect of SQ-LNS on birth weight, length and head circumference varied by pre-pregnancy Hb categories. No significant differences in pooled mean Z-scores were observed for any Hb category >110 g/L, and no differences were found for Arm 1 vs Arm 2 across any Hb categories. For women with Hb 90–99 g/L pooled mean differences (95% CI) in the Z-scores for length (0.60 (0.03 to 1.23)), weight (0.50 (0.11 to 0.89)) and head circumference (0.26 (0.02 to 0.51)) were greatest for Arm 1 versus Arm 3. For women with Hb 100–109 g/L in Arm 1 versus Arm 3, pooled mean difference (95% CI) in birth weight Z-scores was significantly greater (0.33 (0.24 to 0.42)). Arm 2 vs Arm 3 women with Hb 90–99 g/L had greater birth weight Z-scores (0.14 (0.05 to 0.22)). Conclusion The findings highlight the importance of identifying women preconception for whom nutrition interventions may have the greatest impact on fetal growth.
Response of reticulocyte and red blood cell indices to single-dose intravenous iron in pregnant women with moderate iron deficiency anemia: secondary analysis of the RAPIDIRON trial Manjunath S. Somannavar, Sudhir Mehta, Dharmesh Kumar Sharma, Seema Mehta, Yogeshkumar S., Umesh Charantimath, Benjamin E. Leiby, Michael K. Georgieff, Zubair H. Aghai, Ashalata Mallapur, Umesh Ramadurg, Radha Sangavi, Praveen Patil, J. P. Akshaykirthan, Rupsa C. Boelig, Mrutyunjaya B. Bellad, Richard J. Derman Journal of Maternal Fetal and Neonatal Medicine, 2026 BACKGROUND: Iron deficiency anemia in pregnancy is a significant health concern. Reticulocyte hemoglobin equivalent (Ret-He) and immature reticulocyte fraction (IRF) are emerging as early markers, yet their response to different iron therapies in pregnancy is underexplored. OBJECTIVE: To determine whether intravenous single-dose iron administration produces a more favorable effect on reticulocyte indices than oral iron therapy in anemic pregnant women. METHODS: This is a secondary analysis of the RAPIDIRON Trial, a multicenter, three-arm randomized controlled trial comparing ferric carboxymaltose (FCM), ferric derisomaltose (FDM) and standard oral ferrous sulfate. Reticulocyte hemoglobin equivalent (Ret-He), Immature Reticulocyte Fraction (IRF) and other red blood cell indices including Mean Corpuscular Volume (MCV), Mean Corpuscular Hemoglobin (MCH), Mean Corpuscular Hemoglobin Concentration (MCHC) were measured at baseline (12-16 weeks), mid-gestation (26-30 weeks) and 42 days postpartum. Cord blood indices were assessed at delivery. RESULTS: By 26-30 weeks of gestation, iron deficient anemic women receiving IV iron demonstrated significant improvements in all red cell indices when compared to those receiving oral iron. Specifically, MCV increased by 2.87 fL (95% CI, 2.41-3.33) in the IV FDM group and 3.02 fL (95% CI, 2.54-3.49) in the IV FCM group compared to oral iron. Similarly Ret-He levels were also significantly increased in IV FDM and FCM compared to oral iron (1.32 (1.02, 1.63) and 1.31 (1.01, 1.62) respectively. By 42 days postpartum, intergroup differences in Ret-He, IRF and other parameters were no longer statistically significant, indicating that hematologic parameters had converged across treatment arms, reflecting restoration of iron homeostasis and stabilization of erythropoiesis in all groups. CONCLUSION: Intravenous iron therapy produces a more rapid and pronounced improvement in maternal red cell and reticulocyte indices than oral iron in moderately anemic pregnant women. Ret-He and IRF are emerging as early and sensitive biomarkers of iron availability and erythropoietic activity, with potential clinical utility for early detection of treatment response and optimization of iron therapy in pregnancy.
Risk factors and mortality in infants who received bag and mask ventilation at birth: a secondary analysis from the global network maternal newborn health registry Zubair H. Aghai, Avinash Kavi, Vanessa R. Thorsten, Manjunath S. Somannavar, Ramachandra Bhat, Elizabeth M. McClure, Denise C. Babineau, Archana B. Patel, Sarah Saleem, Sangappa M. Dhaded, Umesh Y. Ramdurg, Blair J. Wylie, Manolo Mazariegos, Antoinette K. Tshefu, Waldemar A. Carlo, Nancy F. Krebs, William A. Petri, Patricia L. Hibberd, Edwin J. Asturias, Sherri L. Bucher, Jackie K. Patterson, Melissa S. Bauserman, Fabian Esamai, Robert L. Goldenberg, Rupsa C. Boelig, Shivaprasad S. Goudar, Richard J. Derman Journal of Perinatology, 2026 Objective To identify risk factors for bag and mask ventilation (BMV) and compare mortality outcomes between infants who did and did not receive BMV. Study design Secondary analysis of data from the seven sites of the Global Network Maternal Newborn Health registry, including fresh stillbirths and live births ≥ 1500 grams from 2017 to 2023. Results A total of 171 279 births (98.9% live births, 1.1% fresh stillbirths) were included. BMV was administered in 3.9% of cases. Maternal education, labor complications, delivery location, and prematurity were identified as major risk factors for receiving BMV. Adjusted relative risks (95% CI) for very early neonatal mortality with BMV was 26.18 (23.02–29.79), early neonatal mortality 19.08 (17.40–20.93), neonatal mortality 14.23 (13.08,15.49, mortality < 42 days 12.86 (11.84,13.97) and asphyxia-related deaths was and 2.42 (2.11, 2.77). Conclusion These finding underscore the importance of early identification of maternal and perinatal factors associated with receiving BMV to improve neonatal outcomes.
Does Adherence Modify Low-Dose Aspirin Effects in Pregnancy? Post Hoc Analysis From a Multi-Centre Trial Musaku Mwenechanya, Abigail Mwapule Tembo, Elwyn Chomba, Matthew K. Hoffman, Shivaprasad S. Goudar, Janet L. Moore, Mrityunjay C. Metgud, Manjunath S. Somannavar, Jean Okitawutshu, Adrien L. Lokangaka, Antoinette K. Tshefu, Carl L. Bose, Melissa S. Bauserman, Lester Figueroa, Ana Garces, Nancy F. Krebs, Saleem Jessani, Sarah Saleem, Robert L. Goldenberg, Kunal Kurhe, Prabir Das, Archana B. Patel, Patricia L. Hibberd, Paul Nyongesa, Fabian Esamai, Sherri L. Bucher, Norman Goco, Jennifer J. Hemingway‐Foday, Denise C. Babineau, Elizabeth M. McClure, Robert M. Silver, Richard J. Derman, Waldemar A. Carlo, and BJOG an International Journal of Obstetrics and Gynaecology, 2026 Objective To evaluate if the effect of low‐dose aspirin (LDA) commenced between 6 and 13 weeks of gestational age (GA) on preterm delivery (PTD) is modified by total exposure. Design Post hoc analysis of a randomized controlled trial. Setting Hospitals in low‐resource settings in Africa, Asia and Latin America. Population Outcomes were obtained for 11 908/11943 women at 6 0/7 to 13 6/7 weeks' GA randomized. Methods Women received prepackaged two‐week medication allotments. Adherence was assessed by pill counts every 2 weeks. Estimated relative risk and 95% confidence interval data for each outcome at each GA of treatment initiation weeks were obtained by fitting a Poisson model to each outcome, adjusting for site, treatment arm and GA at treatment initiation. Main Outcomes Measures The primary outcome was PTD. Secondary outcomes included PTD < 34 weeks and perinatal mortality including analysis by region. Results The median gestational age at treatment initiation was 10.1 weeks (IQR 8.6, 12.0). 85.5% of the mothers had over 90% adherence to treatment. For each 1 week increase of GA at treatment initiation, the treatment risk ratio did not change for PTD [RR 0.97 (95% CI, 0.93, 1.02)], PTD < 34 weeks [< 0.98 (0.89, 1.07)] or perinatal mortality [1.04 (0.96, 1.12)], with no evidence of effect modification. For each 5% increase in adherence, the treatment risk ratio did not change for PTD [1.01 (0.99, 1.04)], PTD < 34 weeks [< 0.99 (0.95, 1.03)] or perinatal mortality [1.02 (0.98, 1.06)], indicating no meaningful interaction with adherence. There was no effect modification by region. Conclusions This analysis shows that the results of PTD, PTD < 34 weeks and perinatal mortality were not dependent on the timing of the initiation or adherence to treatment. Trial Registration ClinicalTrials.gov identifier: NCT02409680
Single-dose intravenous iron vs oral iron for treatment of maternal iron deficiency anemia: a randomized clinical trial Richard J. Derman, Mrutyunjaya B. Bellad, Manjunath S. Somannavar, Sudhir Bhandari, Sudhir Mehta, Seema Mehta, Dharmesh Kumar Sharma, S Yogeshkumar, Umesh Charantimath, Amaresh P. Patil, Ashalata A. Mallapur, Umesh Ramadurg, Radha Sangavi, Praveen S. Patil, Subarna Roy, Phaniraj Vastrad, Chander Shekhar, Benjamin E. Leiby, Rebecca L. Hartman, Michael Georgieff, Stephen Mennemeyer, Zubair Aghai, Simal Thind, Rupsa C. Boelig American Journal of Obstetrics and Gynecology, 2025
The World Health Organization Antenatal CorTicosteroids for Improving Outcomes in preterm Newborns (ACTION-III) Trial: study protocol for a multi-country, multi-centre, double-blind, three-arm, placebo-controlled, individually randomized trial of antenatal corticosteroids for women at high probability of late preterm birth in hospitals in low- resource countries , Temitope Adesiji Adegboyega, Ebunoluwa Aderonke Adejuyigbe, Olubukola Adeponle Adesina, Babalola Adeyemi, Salahuddin Ahmed, Francis Akinkunmi, Jalemba Aluvaala, Henry Anyabolu, Shabina Ariff, Sugandha Arya, Ibraheem Awowole, Adejumoke Idowu Ayede, Neelofur Babar, Sumitra Bachani, Rajiv Bahl, Abdullah H. Baqui, Harish Chellani, Saleha Begum Chowdhury, Lynn M. Coppola, Simon Cousens, Pradeep K. Debata, Ayesha de Costa, Sangappa M. Dhaded, Kasturi V. Donimath, Adegoke Gbadegesin Falade, Shivaprasad S. Goudar, Shuchita Gupta, George N. Gwako, Theresa Azonima Irinyenikan, Dennis Anthony Isah, Nigar Jabeen, Arshia Javed, Naima T. Joseph, Rasheda Khanam, John Kinuthia, Oluwafemi Kuti, Tina Lavin, Ahmed R. Laving, Sandhya Maranna, Nicole Minckas, Pratima Mittal, Diwakar Mohan, Sidrah Nausheen, My Huong Nguyen, Olufemi T. Oladapo, Olanike Abosede Olutekunbi, Rosena Olubanke Oluwafemi, Alfred Osoti, Yeshita V. Pujar, Zahida P. Qureshi, Suman P. N. Rao, Sophie Sarrassat, M. A. Shahed, Mohammod Shahidullah, Lumaan Sheikh, Manjunath S. Somannavar, Sajid Soofi, Jyotsna Suri, Sunil S. Vernekar, Joshua P. Vogel, Nitya Wadhwa, Prakash K. Wari, Fred Were, Blair J. Wylie Trials, 2024
Effects of the WHO Labour Care Guide on cesarean section in India: a pragmatic, stepped-wedge, cluster-randomized pilot trial Joshua P. Vogel, Yeshita Pujar, Sunil S. Vernekar, Elizabeth Armari, Veronica Pingray, Fernando Althabe, Luz Gibbons, Mabel Berrueta, Manjunath Somannavar, Alvaro Ciganda, Rocio Rodriguez, Savitri Bendigeri, Jayashree Ashok Kumar, Shruti Bhavi Patil, Aravind Karinagannanavar, Raveendra R. Anteen, Pavithra Mallappa Ramachandrappa, Shukla Shetty, Latha Bommanal, Megha Haralahalli Mallesh, Suman S. Gaddi, Shaila Chikkagowdra, Bellara Raghavendra, Caroline S. E. Homer, Tina Lavender, Pralhad Kushtagi, G. Justus Hofmeyr, Richard Derman, Shivaprasad Goudar Nature Medicine, 2024
RAPIDIRON Trial follow-up study — the RAPIDIRON-KIDS Study: protocol of a prospective observational follow-up study Richard J. Derman, Roopa B. Bellad, Mrutyunjaya B. Bellad, Jesse Bradford-Rogers, Michael K. Georgieff, Zubair H. Aghai, Simal Thind, Michael Auerbach, Rupsa Boelig, Benjamin E. Leiby, Vanessa Short, S. Yogeshkumar, Umesh S. Charantimath, Manjunath S. Somannavar, Ashalata A. Mallapur, Ramesh Pol, Umesh Ramadurg, Radha Sangavi, Basavaraj V. Peerapur, Nasima Banu, Praveen S. Patil, Amaresh P. Patil, Subarna Roy, Phaniraj Vastrad, Dennis Wallace, Hemang Shah, Shivaprasad S. Goudar Trials, 2023
Pregnancy outcomes in preterm multiple gestations: Results from a prospective study in India and Pakistan (PURPOSe) Gowdar Guruprasad, Chaitali R. Raghoji, Sangappa M. Dhaded, Shiyam Sunder Tikmani, Sarah Saleem, Shivaprasad S. Goudar, Kay Hwang, S. Yogeshkumar, Manjunath S. Somannavar, Sayyeda Reza, Haleema Yasmin, Janet L. Moore, Carla M. Bann, Elizabeth M. McClure, Robert L. Goldenberg, the PURPOSe Study Group BJOG an International Journal of Obstetrics and Gynaecology, 2023
Group B streptococcal prevalence in internal organs and placentas of deceased neonates and stillbirths in South Asia Mangala G. Kallapur, Najia K. Ghanchi, Sheetal U. Harakuni, Manjunath S. Somannavar, Imran Ahmed, Elizabeth Fogleman, Kay Hwang, Jean Kim, Sarah Saleem, Shivaprasad S. Goudar, Shiyam Sunder Tikmani, Sangappa M. Dhaded, Gowdar Guruprasad, Haleema Yasmin, S. Yogeshkumar, Elizabeth M. McClure, Robert L. Goldenberg, the PURPOSe Study Group BJOG an International Journal of Obstetrics and Gynaecology, 2023
Neonatal mortality among preterm infants admitted to neonatal intensive care units in India and Pakistan: A prospective study Sarah Saleem, Shiyam Sunder Tikmani, Shivaprasad S. Goudar, Kay Hwang, Sangappa Dhaded, Gowder Guruprasad, Naveen G. Nadig, Varun B. Kusagur, Lingaraja Gowda C. Patil, E. S. Siddartha, S. Yogeshkumar, Manjunath S. Somannavar, Sana Roujani, Mashal Khan, Mehmood Shaikh, Muhammad Hanif, Carla M. Bann, Elizabeth M. McClure, Robert L. Goldenberg, the PURPOSE Study Group BJOG an International Journal of Obstetrics and Gynaecology, 2023
The Global Network COVID-19 studies: a review Seemab Naqvi, Sarah Saleem, Sk Masum Billah, Janet Moore, Musaku Mwenechanya, Waldemar A. Carlo, Fabian Esamai, Sherri Bucher, Richard J. Derman, Shivaprasad S. Goudar, Manjunath Somannavar, Archana Patel, Patricia L. Hibberd, Lester Figueroa, Nancy F. Krebs, William A. Petri, Adrien Lokangaka, Melissa Bauserman, Marion Koso‐Thomas, Elizabeth M. McClure, Robert L. Goldenberg BJOG an International Journal of Obstetrics and Gynaecology, 2023
The PURPOSe cause of death study in stillbirths and neonatal deaths in India and Pakistan: A review Robert L. Goldenberg, Sarah Saleem, Shivaprasad S. Goudar, Janet Moore, Gowdar Guruprasad, Vardendra Kulkarni, Sangappa M. Dhaded, Shiyam Sunder Tikmani, Sidrah Nausheen, Shazia Masheer, Mangala G. Kallapur, Najia K. Ghanchi, Sheetal U. Harakuni, Imran Ahmed, Kay Hwang, S. Yogeshkumar, Manjunath S. Somannavar, Haleema Yasmin, Jean Kim, Carla M. Bann, Robert M. Silver, Elizabeth M. McClure, the PURPOSe Study Group BJOG an International Journal of Obstetrics and Gynaecology, 2023
COVID-19 symptoms and antibody positivity among unvaccinated pregnant women: An observational study in seven countries from the Global Network Avinash Kavi, Shivaprasad S. Goudar, Manjunath S. Somannavar, Janet L. Moore, Richard J. Derman, Sarah Saleem, Seemab Naqvi, Sk Masum Billah, Rashidul Haque, Lester Figueroa, Manolo Mazariegos, Adrien Lokangaka, Antoinette Tshefu, Fabian Esamai, Musaku Mwenechanya, Elwyn Chomba, Archana Patel, Prabirkumar Das, Melissa Bauserman, William A. Petri, Nancy F. Krebs, Waldemar A. Carlo, Sherri Bucher, Patricia L. Hibberd, Marion Koso‐Thomas, Elizabeth M. McClure, Robert L. Goldenberg BJOG an International Journal of Obstetrics and Gynaecology, 2023
Aspirin delays the onset of hypertensive disorders of pregnancy among nulliparous pregnant women: A secondary analysis of the ASPIRIN trial Avinash Kavi, Matthew K. Hoffman, Manjunath S. Somannavar, Mrityunjay C. Metgud, Shivaprasad S. Goudar, Janet Moore, Eleanor Nielsen, Norman Goco, Elizabeth M. McClure, Adrien Lokangaka, Antoinette Tshefu, Melissa Bauserman, Musaku Mwenechanya, Elwyn Chomba, Waldemar A. Carlo, Lester Figueroa, Nancy F. Krebs, Saleem Jessani, Sarah Saleem, Robert L. Goldenberg, Prabirkumar Das, Archana Patel, Patricia L. Hibberd, Fabian Esamai, Sherri Bucher, Marion Koso‐Thomas, Robert Silver, Richard J. Derman BJOG an International Journal of Obstetrics and Gynaecology, 2023
The impact of risk factors on aspirin's efficacy for the prevention of preterm birth Emily E. Nuss, Matthew K. Hoffman, Shivaprasad S. Goudar, Avinash Kavi, Mrityunjay Metgud, Manjunath Somannavar, Jean Okitawutshu, Adrien Lokangaka, Antoinette Tshefu, Melissa Bauserman, Abigail Mwapule Tembo, Elwyn Chomba, Waldemar A. Carlo, Lester Figueroa, Nancy F. Krebs, Saleem Jessani, Sarah Saleem, Robert L. Goldenberg, Kunal Kurhe, Prabir Das, Patricia L. Hibberd, Emmah Achieng, Paul Nyongesa, Fabian Esamai, Edward A. Liechty, Sherri Bucher, Norman Goco, Jennifer Hemingway-Foday, Janet Moore, Elizabeth M. McClure, Robert M. Silver, Richard J. Derman American Journal of Obstetrics and Gynecology Mfm, 2023
Pathogens identified in the internal tissues and placentas of stillbirths: results from the prospective, observational PURPOSe study Sheetal U. Harakuni, Manjunath S. Somannavar, Najia K. Ghanchi, Imran Ahmed, Afia Zafar, Jean Kim, Shiyam Sunder Tikmani, Kay Hwang, Sarah Saleem, Shivaprasad S. Goudar, Sangappa Dhaded, Gowder Guruprasad, Haleema Yasmin, S. Yogeshkumar, Anna Aceituno, Robert M. Silver, Elizabeth M. McClure, R. L. Goldenberg, the PURPOSe Investigators BJOG an International Journal of Obstetrics and Gynaecology, 2023
Safe infant feeding in healthcare facilities: Assessment of infection prevention and control conditions and behaviors in India, Malawi, and Tanzania Bethany A. Caruso, Uriel Paniagua, Irving Hoffman, Karim Manji, Friday Saidi, Christopher R. Sudfeld, Sunil S. Vernekar, Mohamed Bakari, Christopher P. Duggan, George C. Kibogoyo, Rodrick Kisenge, Sarah Somji, Eddah Kafansiyanji, Tisungane Mvalo, Naomie Nyirenda, Melda Phiri, Roopa Bellad, Sangappa Dhaded, Chaya K. A., Bhavana Koppad, Shilpa Nabapure, Saumya Nanda, Bipsa Singh, S. Yogeshkumar, Katelyn Fleming, Krysten North, Danielle E. Tuller, Katherine E. A. Semrau, Linda Vesel, Melissa F. Young, and Plos Global Public Health, 2023
Cost-effectiveness of low-dose aspirin for the prevention of preterm birth: a prospective study of the Global Network for Women's and Children's Health Research Jackie K Patterson, Simon Neuwahl, Norman Goco, Janet Moore, Shivaprasad S Goudar, Richard J Derman, Matthew Hoffman, Mrityunjay Metgud, Manjunath Somannavar, Avinash Kavi, Jean Okitawutshu, Adrien Lokangaka, Antoinette Tshefu, Carl L Bose, Abigail Mwapule, Musaku Mwenechanya, Elwyn Chomba, Waldemar A Carlo, Javier Chicuy, Lester Figueroa, Nancy F Krebs, Saleem Jessani, Sarah Saleem, Robert L Goldenberg, Kunal Kurhe, Prabir Das, Archana Patel, Patricia L Hibberd, Emmah Achieng, Paul Nyongesa, Fabian Esamai, Sherri Bucher, Edward A Liechty, Brian W Bresnahan, Marion Koso-Thomas, Elizabeth M McClure Lancet Global Health, 2023
COVID-19 antibody positivity over time and pregnancy outcomes in seven low-and-middle-income countries: A prospective, observational study of the Global Network for Women's and Children's Health Research Robert L. Goldenberg, Sarah Saleem, Sk Masum Billah, Jean Kim, Janet L. Moore, Najia Karim Ghanchi, Rashidul Haque, Lester Figueroa, Alejandra Ayala, Adrien Lokangaka, Antoinette Tshefu, Shivaprasad S. Goudar, Avinash Kavi, Manjunath Somannavar, Fabian Esamai, Musaku Mwenechanya, Elwyn Chomba, Archana Patel, Prabir Das, Wilfred Injera Emonyi, Samuel Edidi, Madhavi Deshmukh, Biplob Hossain, Shahjahan Siraj, Manolo Mazariegos, Ana L. Garces, Melissa Bauserman, Carl L. Bose, William A. Petri, Nancy F. Krebs, Richard J. Derman, Waldemar A. Carlo, Edward A. Liechty, Patricia L. Hibberd, Marion Koso‐Thomas, Nalini Peres‐da‐Silva, Tracy L. Nolen, Elizabeth M. McClure BJOG an International Journal of Obstetrics and Gynaecology, 2023
Feeding practices and growth patterns of moderately low birthweight infants in resource-limited settings: results from a multisite, longitudinal observational study Linda Vesel, Roopa M Bellad, Karim Manji, Friday Saidi, Esther Velasquez, Christopher R Sudfeld, Katharine Miller, Mohamed Bakari, Kristina Lugangira, Rodrick Kisenge, Nahya Salim, Sarah Somji, Irving Hoffman, Kingsly Msimuko, Tisungane Mvalo, Fadire Nyirenda, Melda Phiri, Leena Das, Sangappa Dhaded, Shivaprasad S Goudar, Veena Herekar, Yogesh Kumar, M B Koujalagi, Gowdar Guruprasad, Sanghamitra Panda, Latha G Shamanur, Manjunath Somannavar, Sunil S Vernekar, Sujata Misra, Linda Adair, Griffith Bell, Bethany A Caruso, Christopher Duggan, Katelyn Fleming, Kiersten Israel-Ballard, Eliza Fishman, Anne C C Lee, Stuart Lipsitz, Kimberly L Mansen, Stephanie L Martin, Rana R Mokhtar, Krysten North, Arthur Pote, Lauren Spigel, Danielle E Tuller, Melissa Young, Katherine E A Semrau BMJ Open, 2023
The causes of preterm neonatal deaths in India and Pakistan (PURPOSe): a prospective cohort study Sangappa M Dhaded, Sarah Saleem, Shivaprasad S Goudar, Shiyam Sunder Tikmani, Kay Hwang, Gowdar Guruprasad, Gayathri H Aradhya, Varun B Kusagur, Lingaraja Gowda C Patil, S Yogeshkumar, Manjunath S Somannavar, Sayyeda Reza, Sana Roujani, Jamal Raza, Haleema Yasmin, Anna Aceituno, Lindsay Parlberg, Jean Kim, Janet Moore, Carla M Bann, Robert M Silver, Robert L Goldenberg, Elizabeth M McClure, Shivaprasad Goudar, Sangappa M Dhaded, Mahantesh B Nagmoti,, Manjunath S Somannavar, S Yogeshkumar, Sheetal Harakuni, Gowdar Guruprasad, Gayathri H Aradhya, Naveen Nadig, Varun Kusgur, Chaitali R Raghoji, B Sarvamangala, Veena Prakash,, Upendra Kumar Joish, G K Mangala, K S Rajashekhar, K Byranahalli Sunilkumar, Vardendra Kulkarni, ES Siddartha, Lingaraja Gowda C Patil, Sneharoopa Pujar, Shobha Dhananjaya, TS Nagaraj, MU Jeevika, Reddy R Harikiran, Sarah Saleem, Shiyam Sunder Tikmani, Afia Zafar, Imran Ahmed, Zeeshan Uddin, Najia Ghanchi, Sana Roujani, Shabina Ariff, Lumaan Sheikh, Waseem Mirza, Haleema Yasmin, Jamal Raza, Jai Prakash, Furqan Haider, Anna Aceituno, Lindsay Parlberg, Janet L Moore, Kay Hwang, Suchita Parepelli, Jean Kim, Carla Bann, Elizabeth McClure, Robert Goldenberg, Robert Silver Lancet Global Health, 2022
The causes of stillbirths in south Asia: results from a prospective study in India and Pakistan (PURPOSe) Elizabeth M McClure, Sarah Saleem, Shivaprasad S Goudar, Shiyam Sunder Tikmani, Sangappa M Dhaded, Kay Hwang, Gowdar Guruprasad, Dhananjaya Shobha, B Sarvamangala, S Yogeshkumar, Manjunath S Somannavar, Sana Roujani, Sayyeda Reza, Jamal Raza, Haleema Yasmin, Anna Aceituno, Lindsay Parlberg, Jean Kim, Carla M Bann, Robert M Silver, Robert L Goldenberg, Shivaprasad Goudar, Sangappa M Dhaded, Mahantesh B Nagmoti, Manjunath S Somannavar, S Yogeshkumar, Gowdar Guruprasad, Gayathri H Aradhya, Naveen Nadig, Varun Kusgur, Chaitali R Raghoji, B Sarvamangala, Veena Prakash,, Upendra Kumar Joish, G K Mangala, K S Rajashekhar, Sunil Kumar, Vardendra Kulkarni, Sarah Saleem, Shiyam Sunder Tikmani, Afia Zafar, Imran Ahmed, Zeeshan Uddin, Najia Ghanchi, Shabina Ariff, Lumaan Sheikh, Waseem Mirza, Haleema Yasmin, Jamal Raza, Jai Prakash, Furqan Haider, Anna Aceituno, Lindsay Parlberg, Janet L Moore, Kay Hwang, Suchita Parepelli, Jean Kim, Carla Bann, Elizabeth McClure, Robert Goldenberg Lancet Global Health, 2022
Improved first trimester maternal iodine status with preconception supplementation: The Women First Trial Amy E. Young, Jennifer F. Kemp, Charis Uhlson, Jamie L. Westcott, Sumera A. Ali, Sarah Saleem, Ana Garcès, Lester Figueroa, Manjunath S. Somannavar, Shivaprasad S. Goudar, K. Michael Hambidge, Audrey E. Hendricks, Nancy F. Krebs, the Women First Preconception Maternal Nutrition Trial Group Maternal and Child Nutrition, 2021
Preventable stillbirths in India and Pakistan: a prospective, observational study RL Goldenberg, S Saleem, SS Goudar, RM Silver, SS Tikmani, G Guruprasad, SM Dhaded, H Yasmin, K Bano, MS Somannavar, S Yogeshkumar, K Hwang, A Aceituno, L Parlberg, EM McClure, the PURPOSE Study Group BJOG an International Journal of Obstetrics and Gynaecology, 2021
Growth from Birth Through Six Months for Infants of Mothers in the “Women First” Preconception Maternal Nutrition Trial Nancy F. Krebs, K. Michael Hambidge, Jamie L. Westcott, Ana L. Garcés, Lester Figueroa, Antoinette K. Tsefu, Adrien L. Lokangaka, Shivaprasad S. Goudar, Sangappa M. Dhaded, Sarah Saleem, Sumera Aziz Ali, Carl L. Bose, Richard J. Derman, Robert L. Goldenberg, Vanessa R. Thorsten, Amaanti Sridhar, Dhuly Chowdhury, Abhik Das, Justin Gado, Manjunath S. Somannavar, Veena Herekar, Omrana Pasha, Umber Khan, Elizabeth M. McClure, Marion Koso-Thomas Journal of Pediatrics, 2021
Antenatal dexamethasone for early preterm birth in low-resource countries O. Oladapo, Joshua P. Vogel, G. Piaggio, M. Nguyen, F. Althabe, A. M. Gülmezoglu, R. Bahl, Suman P N Rao, A. De Costa, Shuchita Gupta, A. Baqui, R. Khanam, M. Shahidullah, S. B. Chowdhury, Salahuddin Ahmed, N. Begum, A. D Roy, M. Shahed, I. A. Jaben, F. Yasmin, M. Rahman, A. Ara, Soofia Khatoon, G. Ara, S. Akter, N. Akhter, P. R. Dey, M. Sabur, M. T. Azad, S. F. Choudhury, M. A. Matin, S. Goudar, S. Dhaded, M. Metgud, Yeshita V. Pujar, M. Somannavar, Sunil S. Vernekar, Veena Herekar, S. Bidri, S. Mathapati, P. Patil, M. Patil, M. R. Gudadinni, Hidaytullah R Bijapure, Ashalata A. Mallapur, Geetanjali Katageri, Sumangala B Chikkamath, B. Yelamali, R. Pol, S. Misra, L. Das, S. Nanda, Rashmita Nayak, Bipsa Singh, Z. Qureshi, F. Were, A. Osoti, G. Gwako, A. Laving, J. Kinuthia, H. Mohamed, N. Aliyan, A. Barassa, E. Kibaru, M. Mbuga, Lydia Thuranira, N. Githua, B. Lusweti, A. Ayede, A. Falade, O. Adesina, A. Agunloye, O. O. Iyiola, W. Sanni, I. K. Ejinkeonye, Hadiza A. Idris, C. V. Okoli, T. Irinyenikan, O. Olubosede, O. Bello, O. Omololu, Olanike A Olutekunbi, A. Akintan, O. Owa, R. Oluwafemi, I. P. Eniowo, A. Fabamwo, E. Disu, J. Agbara, E. Adejuyigbe, O. Kuti, H. Anyabolu, I. Awowole, A. Fehintola, B. Kuti, A. Isah, E. Olateju, Olusanya Abiodun, O. F. Dedeke, F. Akinkunmi, L. Oyeneyin, O. Adesiyun, H. Raji, A. Ande, I. Okonkwo, Shabina Ariff, S. Soofi, Lumaan Sheikh, Saima Zulfiqar, S. Omer, Raheel Sikandar, Salma Sheikh, D. Giordano, Hugo Gamerro, G. Carroli, José Carvalho, J. Neilson, E. Molyneux, K. Yunis, K. Mugerwa, H. Chellani New England Journal of Medicine, 2020
Institutional deliveries and stillbirth and neonatal mortality in the Global Network's Maternal and Newborn Health Registry Shivaprasad S. Goudar, Norman Goco, Manjunath S. Somannavar, Avinash Kavi, Sunil S. Vernekar, Antoinette Tshefu, Elwyn Chomba, Ana L. Garces, Sarah Saleem, Farnaz Naqvi, Archana Patel, Fabian Esamai, Carl L. Bose, Waldemar A. Carlo, Nancy F. Krebs, Patricia L. Hibberd, Edward A. Liechty, Marion Koso-Thomas, Tracy L. Nolen, Janet Moore, Pooja Iyer, Elizabeth M. McClure, Robert L. Goldenberg, Richard J. Derman Reproductive Health, 2020
Low-Dose Aspirin for the Prevention of Preterm Delivery in Nulliparous Women with a Singleton Pregnancy (ASPIRIN): A Randomized, Double-blind, Placebo-Controlled Trial Matthew K. Hoffman, Shivaprasad S. Goudar, Bhalachandra S. Kodkany, Mrityunjay Metgud, Manjunath Somannavar, Jean Okitawutshu, Adrien Lokangaka, Antoinette Tshefu, Carl L. Bose, Abigail Mwapule, Musaku Mwenechanya, Elwyn Chomba, Waldemar A. Carlo, Javier Chicuy, Lester Figueroa, Ana Garces, Nancy F. Krebs, Saleem Jessani, Farnaz Zehra, Sarah Saleem, Robert L. Goldenberg, Kunal Kurhe, Prabir Das, Archana Patel, Patricia L. Hibberd, Emmah Achieng, Paul Nyongesa, Fabian Esamai, Edward A. Liechty, Norman Goco, Jennifer Hemingway-Foday, Janet Moore, Tracy L. Nolen, Elizabeth M. McClure, Marion Koso-Thomas, Menachem Miodovnik, R. Silver, Richard J. Derman Obstetrical and Gynecological Survey, 2020
Low-dose aspirin for the prevention of preterm delivery in nulliparous women with a singleton pregnancy (ASPIRIN): a randomised, double-blind, placebo-controlled trial Matthew K Hoffman, Shivaprasad S Goudar, Bhalachandra S Kodkany, Mrityunjay Metgud, Manjunath Somannavar, Jean Okitawutshu, Adrien Lokangaka, Antoinette Tshefu, Carl L Bose, Abigail Mwapule, Musaku Mwenechanya, Elwyn Chomba, Waldemar A Carlo, Javier Chicuy, Lester Figueroa, Ana Garces, Nancy F Krebs, Saleem Jessani, Farnaz Zehra, Sarah Saleem, Robert L Goldenberg, Kunal Kurhe, Prabir Das, Archana Patel, Patricia L Hibberd, Emmah Achieng, Paul Nyongesa, Fabian Esamai, Edward A Liechty, Norman Goco, Jennifer Hemingway-Foday, Janet Moore, Tracy L Nolen, Elizabeth M McClure, Marion Koso-Thomas, Menachem Miodovnik, R Silver, Richard J Derman, Emmah Achieng, Melissa Bauserman, Carl Bose, Sherri Bucher, Waldemar Carlo, Umesh S Charantimath, Javier Chicuy, Elwyn Chomba, Prabir Das, Richard Derman, Fabian Esamai, Lester Figueroa, MS Ganachari, Ana Garces, Noman Goco, Robert Goldenberg, Shivaprasad Goudar, Jennifer Hemingway-Foday, Patricia Hibberd, Matthew Hoffman, Narayan V Honnungar, Saleem Jessani, Avinash Kavi, Bhalachandra Kodkany, Marion Koso-Thomas, Nancy Krebs, Yogesh Kumar Shashikanth, Kunal Kurhe, Edward Liechty, Adrien Lokangaka, Emily MacGuire, Ashalata A Mallapur, Elizabeth McClure, Mrityunjay Metgud, Menachem Miodovnik, Janet Moore, Abigail Mwapule, Musaku Mwenechanya, Farnaz Naqvi, Seemab Naqvi, Robert Nathan, Tracy Nolen, Paul Nyongesa, Jean Okitawutshu, Suchita Parepalli, Archana Patel, Umesh Y Ramadurg, Sarah Saleem, Robert Silver, Manjunath Somannavar, Zahid Soomro, Antoinette Tshefu, Sunil S Vernekar, Dennis Wallace, Farnaz Zehra Lancet, 2020
Maternal characteristics affect fetal growth response in the women first preconception nutrition trial K Michael Hambidge, Carla M. Bann, Elizabeth M. McClure, Jamie E. Westcott, Ana Garcés, Lester Figueroa, Shivaprasad S. Goudar, Sangappa M. Dhaded, Omrana Pasha, Sumera A. Ali, Richard J. Derman, Robert L. Goldenberg, Marion Koso-Thomas, Manjunath S. Somannavar, Veena Herekar, Umber Khan, Nancy F. Krebs Nutrients, 2019
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