COVID-19 on Elective Surgery Outcomes in a Brazilian Tertiary Hospital: A Retrospective Cohort Study Dilson Palhares Ferreira, Cláudia Vicari Bolognani, Luana Argollo Souza Fernandes, Matheus Serwy Fiuza de Morais, Lucas Lourenço Santos Souza, Mariah Vicari Bolognani, Giovana Alves Madureira, Levy Aniceto Santana, Fábio Ferreira Amorim Medical Science Monitor, 2025 BACKGROUND The COVID-19 pandemic significantly disrupted elective surgical services worldwide, especially in resource-limited settings, raising concerns about surgical safety and care quality. This study compared postoperative hospital mortality, day-of-surgery cancellations, and surgical reintervention rates before, during, and after the COVID-19 pandemic among elective surgeries scheduled at a tertiary public hospital in the Federal District, Brazil. MATERIAL AND METHODS This retrospective cohort study included all consecutive adult surgeries scheduled at a tertiary public hospital in the Federal District between January 2018 and December 2022. Trends in hospital mortality, day-of-surgery cancellations, and surgical reintervention rates were evaluated across the pre-pandemic (March 2018-February 2020), lockdown (March 2020-August 2020), and post-lockdown (September 2020-February 2022) periods using the Cochran-Armitage test for trend and multivariate logistic regression analysis. RESULTS Among 8806 scheduled surgeries, 5482 (62.3%) were elective. The number of elective procedures significantly decreased during the lockdown (P<0.001). Day-of-surgery cancellations decreased independently during the lockdown compared with the pre-pandemic period (odds ratio [OR]: 0.556; 95% CI: 0.448-0.691; P<0.001) and showed no significant difference with the post-lockdown period (OR: 0.828; 95% CI: 0.650-1.055; P=0.126). Surgical reintervention rates were unchanged during lockdown (OR: 0.888; 95% CI: 0.662-1.192; P=0.274) but declined significantly in the post-lockdown period (OR: 0.534; 95%CI: 0.390-0.733; P<0.001). No significant differences were found in postoperative hospital mortality across the 3 periods (P=0.847). CONCLUSIONS Reductions in cancellations and reinterventions, without an increase in mortality, were observed in the provision of elective surgical care during the pandemic.
Quality indicators for hospital burn care: a scoping review Denise R. Rabelo Suzuki, Levy Aniceto Santana, Juliana Elvira H. Guerra Ávila, Fábio Ferreira Amorim, Guilherme Pacheco Modesto, Leila Bernarda Donato Gottems, Vinicius Maldaner BMC Health Services Research, 2024 Background Burn treatments are complex, and for this reason, a specialised multidisciplinary approach is recommended. Evaluating the quality of care provided to acute burn patients through quality indicators makes it possible to develop and implement measures aiming at better results. There is a lack of information on which indicators to evaluate care in burn patients. The purpose of this scoping review was to identify a list of quality indicators used to evaluate the quality of hospital care provided to acute burn patients and indicate possible aspects of care that do not have specific indicators in the literature. Method A comprehensive scoping review (PRISMA-ScR) was conducted in four databases (PubMed, Cochrane Library, Embase, and Lilacs/VHL) between July 25 and 30, 2022 and redone on October 6, 2022. Potentially relevant articles were evaluated for eligibility. General data and the identified quality indicators were collected for each included article. Each indicator was classified as a structure, process, or outcome indicator. Results A total of 1548 studies were identified, 82 were included, and their reference lists were searched, adding 19 more publications. Thus, data were collected from 101 studies. This review identified eight structure quality indicators, 72 process indicators, and 19 outcome indicators listed and subdivided according to their objectives. Conclusion This study obtained a list of quality indicators already used to monitor and evaluate the hospital care of acute burn patients. These indicators may be useful for further research or implementation in quality improvement programs. Trial Registration Protocol was registered on the Open Science Framework platform on June 27, 2022 (https://doi.org/10.17605/OSF.IO/NAW85).
Frequency, complications, and mortality of inhalation injury in burn patients: A systematic review and meta-analysis protocol Juliana Elvira Herdy Guerra Avila, Levy Aniceto Santana, Denise Rabelo Suzuki, Vinícius Zacarias Maldaner da Silva, Marcio Luís Duarte, Aline Mizusaki Imoto, Fábio Ferreira Amorim Plos One, 2024 IntroductionBurns are tissue traumas caused by energy transfer and occur with a variable inflammatory response. The consequences of burns represent a public health problem worldwide. Inhalation injury (II) is a severity factor when associated with burn, leading to a worse prognosis. Its treatment is complex and often involves invasive mechanical ventilation (IMV). The primary purpose of this study will be to assess the evidence regarding the frequency and mortality of II in burn patients. The secondary purposes will be to assess the evidence regarding the association between IIs and respiratory complications (pneumonia, airway obstruction, acute respiratory failure, acute respiratory distress syndrome), need for IMV and complications in other organ systems, and highlight factors associated with IIs in burn patients and prognostic factors associated with acute respiratory failure, need for IMV and mortality of II in burn patients.MethodsThis is a systematic literature review and meta-analysis, according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA). PubMed/MEDLINE, Embase, LILACS/VHL, Scopus, Web of Science, and CINAHL databases will be consulted without language restrictions and publication date. Studies presenting incomplete data and patients under 19 years of age will be excluded. Data will be synthesized through continuous (mean and standard deviation) and dichotomous (relative risk) variables and the total number of participants. The means, sample sizes, standard deviations from the mean, and relative risks will be entered into the Review Manager web analysis software (The Cochrane Collaboration).DiscussionDespite the extensive experience managing IIs in burn patients, they still represent an important cause of morbidity and mortality. Diagnosis and accurate measurement of its damage are complex, and therapies are essentially based on supportive measures. Considering the challenge, their impact, and their potential severity, IIs represent a promising area for research, needing further studies to understand and contribute to its better evolution.The protocol of this review is registered on the International prospective register of systematic reviews platform of the Center for Revisions and Disclosure of the University of York, United Kingdom (https://www.crd.york.ac.uk/prospero), under number RD42022343944.
Impact of the COVID-19 Pandemic on Elective and Emergency Surgeries, and Postoperative Mortality in a Brazilian Metropolitan Area: A Time-Series Cohort Study Dilson Palhares Ferreira, Claudia Vicari Bolognani, Levy Santana, Sergio Eduardo Soares Fernandes, Matheus de Moraes, Luana Fernandes, Daniella Queiroz Oliveira, Rosália de Santana, Leila Gottems, Fabio Ferreira Amorim Risk Management and Healthcare Policy, 2024 Purpose: The COVID-19 pandemic posed a worldwide challenge, leading to radical changes in surgical services. The primary objective of the study was to assess the impact of COVID-19 on elective and emergency surgeries in a Brazilian metropolitan area. The secondary objective was to compare the postoperative hospital mortality before and during the pandemic. Patients and Methods: Time-series cohort study including data of all patients admitted for elective or emergency surgery at the hospitals in the Public Health System of Federal District, Brazil, between March 2018 and February 2022, using data extracted from the Hospital Information System of Brazilian Ministry of Health (SIH/DATASUS) on September 30, 2022. A causal impact analysis was used to evaluate the impact of COVID-19 on elective and emergency surgeries and hospital mortality. Results: There were 174,473 surgeries during the study period. There was a reduction in overall (absolute effect per week: -227.5; 95% CI: -307.0 to -149.0), elective (absolute effect per week: -170.9; 95% CI: -232.8 to -112.0), and emergency (absolute effect per week: -57.7; 95% CI: -87.5 to -27.7) surgeries during the COVID-19 period. Comparing the surgeries performed before and after the COVID-19 onset, there was an increase in emergency surgeries (53.0% vs 68.8%, P < 0.001) and no significant hospital length of stay (P = 0.112). The effect of the COVID-19 pandemic on postoperative hospital mortality was not statistically significant (absolute effect per week: 2.1, 95% CI: -0.01 to 4.2). Conclusion: Our study showed a reduction in elective and emergency surgeries during the COVID-19 pandemic, possibly due to disruptions in surgical services. These findings highlight that it is crucial to implement effective strategies to prevent the accumulation of surgical waiting lists in times of crisis and improve outcomes for surgical patients.
Impact of the COVID-19 Pandemic on Births, Vaginal Deliveries, Cesarian Sections, and Maternal Mortality in a Brazilian Metropolitan Area: A Time-Series Cohort Study Dilson Palhares Ferreira, Cláudia Bolognani, Levy Aniceto Santana, Sérgio Eduardo Soares Fernandes, Matheus Serwy Fiuza de Moraes, Luana Argollo Souza Fernandes, Camila de Sousa Pereira, Gabriela Billafan Ferreira, Leila Bernarda Donato Göttems, Fábio Ferreira Amorim International Journal of Women S Health, 2023 Purpose: The COVID-19 pandemic posed a worldwide challenge, leading to radical changes in healthcare. The primary objective of the study was to assess the impact of the COVID-19 pandemic on birth, vaginal delivery, and cesarian section (c-section) rates. The secondary objective was to compare the maternal mortality before and after the pandemic. Patients and Methods: Time-series cohort study including data of all women admitted for childbirth (vaginal delivery or c-section) at the maternities in the Public Health System of Federal District, Brazil, between March 2018 and February 2022, using data extracted from the Hospital Information System of Brazilian Ministry of Health (SIH/DATASUS) on September 30, 2022. Causal impact analysis was used to evaluate the impact of COVID-19 on birth, vaginal delivery, and c-section using the CausalImpact R package, and a propensity score matching was used to evaluate the effect on maternal mortality rate using the Easy R (EZR) software. Results: There were 150,617 births, and considering total births, the effect of the COVID-19 pandemic was not statistically significant (absolute effect per week: 5.5, 95% CI: -24.0-33.4). However, there was an increase in c-sections after COVID-19 (absolute effect per week: 18.1; 95% CI: 11.9-23.9). After propensity score matching, the COVID-19 period was associated with increased maternal mortality (OR: 3.22, 95% CI: 1.53-6.81). The e-value of the adjusted OR for the association between the post-COVID-19 period and maternal mortality was 5.89, with a 95% CI: 2.43, suggesting that unmeasured confounders were unlikely to explain the entirety of the effect. Conclusion: Our study revealed a rise in c-sections and maternal mortality during the COVID-19 pandemic, possibly due to disruptions in maternal care. These findings highlight that implementing effective strategies to protect maternal health in times of crisis and improve outcomes for mothers and newborns is crucial.
Patient safety culture in primary health care: Medical office survey on patient safety culture in a Brazilian family health strategy setting Gleiton Lima Araújo, Fábio Ferreira Amorim, Rafaela Cristina Pereira Santos de Miranda, Flávio Ferreira Pontes Amorim, Levy Aniceto Santana, Leila Bernarda Donato Göttems Plos One, 2022 Study objectives To assess the patient safety culture in Primary Health Care (PHC) setting after the transition to the Family Health Strategy (FHS) model in a Brazilian metropolitan area and compare the results between the categories of health care professionals. Methods A cross-sectional study including 246 workers from primary health care services in Federal District, Brazil. Data collection took place from October to December 2019 through the Medical Office Survey on Patient Safety Culture (MOSPSC) application. Patient safety culture was considered positive when the score was above 60%. For comparisons between the categories of health care professionals’, the ANOVA and Kruskal-Wallis test were used for composite percent positive scores, and Pearson’s chi-square or Fishers exact test for frequency and percentage of positive responses. Results The overall MOSPSC composite percent positive score was 49.9%. Among the 12 dimensions, only three showed a positive patient safety culture: Teamwork (73.1%), Organizational learning (62.9%), and Patient care tracking/follow-up (60.1%). The percentage of positive responses on overall quality assessment (78.1%) and overall patient safety assessment (78.0%) showed a positive evaluation. There was no significant difference in the composite percent positive score of overall MOSPSC (p = 0.135) and the percentage of positive responses on overall patient safety assessment (p = 0.156) between the categories of health care professionals. Overall quality assessment showed a significant difference between job roles (p < 0.001), in which nursing /health care technicians showed a significantly lower score than other job roles. Conclusion The patient safety culture assessment showed a weakness in the patient safety in the PHC services. The MOSPSC and nine of its dimensions presented a negative safety culture assessment, regardless of the high scores in the overall patient safety and quality assessments.
The impact of a low-calorie, low-glycemic diet on systemic lupus erythematosus: a systematic review Aline Mizusaki Imoto, Leila Bernarda Gottems, Ana Lúcia Salomon, Helbert Eustáquio Cardoso e Silva, Império Lombardi Júnior, Maria Stella Peccin, Fábio Ferreira Amorim, Levy Aniceto Santana Advances in Rheumatology, 2021 Background Diet plays a critical role in Systemic Lupus Erythematosus (SLE) patients, impacting on the microbiota composition and, consequently, on the immune response. The objective was to analyze and verify the diet effect on SLE patients. Methods This is a systematic review performed at the Evidences-based Health Lab, Escola Superior em Ciências da Saúde, Brasília (DF), Brazil. In March, 2021, five databases, and grey literature, through JSTOR, Open Grey, and Google Scholar were searched. Randomized Clinical Trials in which SLE patients with calorie restricted, low glycemic index or other diet involving the joint adequacy of these aspects, compared with placebo or different types of diet, were included. Results It was identified in the databases 758 articles; 132 were duplicated; 616 references were screened, and 604 were excluded. After reading the title and abstract, 12 articles were included for full-text reading. After the full-text reading, three studies were included for quantitative analysis. The diet improved the quality of life at 6 (MD 16.30; 5.91;26.69) and 12 weeks (MD 14.60; 0.88;28.32). The GRADE was used to evaluate the quality of evidence. Conclusion There is low evidence that the diet has a positive impact on the quality of life of SLE patients. Trial registration PROSPERO—CRD4202012208.
Functional and joint evaluation in a prospective cohort of patients with severe haemophilia Alexandre Jorge Teixeira Ribeiro, Fábio Ferreira Amorim, Beatriz Mac Dowell Soares, Levy Aniceto Santana, Aline Mizusaki Imoto Haemophilia, 2021 IntroductionArthropathy is the main morbidity of haemophilia. Periodic joint health assessment enables a better understanding of the limitations of these patients.ObjectiveTo evaluate the functional and joint performance in patients with haemophilia at one‐year follow‐up, as well as its association with prophylactic treatment and attendance at scheduled consultations at a haemophilia treatment centre.MethodsThis prospective cohort study included patients with severe haemophilia aged 7 years or more and treated at Fundação Hemocentro de Brasília, Brazil, from January 2014 to December 2018. The Hemophilia Joint Health Score and Functional Independence Score in Hemophilia were assessed at the first consultation and after a one‐year follow‐up.ResultsThe study included 69 patients. The mean age at study recruitment was 22.5 ± 4.5 years, 62.3% of patients aged 18 years or older, and 29 patients were receiving primary prophylaxis (38.0%). There was a positive correlation between HJHS and age and a negative correlation between FISH and age. The worsening HJHS was associated with non‐primary prophylaxis and non‐attendance at scheduled multidisciplinary consultations. The worsening FISH was associated with non‐primary prophylaxis. The correlation between FISH and treatment adherence was significant for the delta.ConclusionThe older the patient with haemophilia, the higher the probability of a worsening of the HJHS. In the presence of more arthropathies, the older the patient, the worse the FISH. Patients receiving primary prophylaxis show better results in the HJHS and FISH when compared to patients receiving secondary prophylaxis and/or on‐demand treatment.
Evidence for the efficacy of tai chi for treating rheumatoid arthritis: An overview of systematic reviews Aline Mizusaki Imoto, Fábio Ferreira Amorim, Henderson Palma, Império Lombardi Júnior, Ana Lúcia Salomon, Maria Stella Peccin, Helbert Eustáquio Cardoso da Silva, Eduardo Signorini Bicas Franco, Leila Göttems, Levy Aniceto Santana Sao Paulo Medical Journal, 2021 BACKGROUND: Rheumatoid arthritis (RA) is a chronic disease with higher prevalence among women aged between 30 and 50 years and general prevalence of 1% worldwide. Interventions promoting improvement of quality of life for individuals with RA are required. Tai Chi appears to be a low-cost alternative, with studies showing positive results from this technique. However, regarding aspects of RA such as pain and sensitivity, studies remain inconclusive. OBJECTIVES: To compare the effectiveness of the Tai Chi method for treating patients diagnosed with rheumatoid arthritis, among systematic reviews. DESIGN AND SETTING: Overview of systematic reviews with Cochrane and non-Cochrane methodology. METHODS: Systematic reviews involving quasi-randomized and randomized clinical trials (RCTs) on use of Tai Chi, with no restrictions regarding the date and language of publication, were included. RESULTS: Three systematic reviews were included. The effects of Tai Chi associated with education and stretching exercises versus education and stretching were evaluated in these reviews. They showed that improvements in the variables of mood, depression and functional index were associated with use of Tai Chi. CONCLUSIONS: The findings suggest that clinical improvement was achieved, although not statistically significant with regard to pain and disease pattern, as assessed using the ACR20 measurement. Improvements relating to disability and quality of life were also seen. There was a low level of evidence and therefore caution in data analysis is recommended. The three studies included showed poor reliability for providing an accurate and complete summary of use of Tai Chi among people diagnosed with rheumatoid arthritis. PROSPERO: CRD42019125501.
Reducing overcrowding in an emergency department: A pilot study Fábio Ferreira Amorim, Karlo Jozefo Quadros de Almeida, Sanderson Cesar Macedo Barbalho, Vanessa de Amorim Teixeira Balieiro, Arnaldo Machado Neto, Guilherme de Freitas Dias, Levy Aniceto Santana, Cristhiane Pinheiro Teixeira Gico de Aguiar, Cláudia Cardoso Gomes da Silva, Sriram Dasu Revista Da Associacao Medica Brasileira, 2019
Undergraduate research in medical education Fábio Ferreira Amorim, Levy Aniceto Santana, Ingrid Lazo Toledo, Edvar Ferreira da Rocha Júnior, Cláudia Cardoso Gomes da Silva, Vanessa de Amorim Teixeira Balieiro, Karlo Jozefo Quadros de Almeida Revista Da Associacao Medica Brasileira, 2017
Testing an image mining approach to obtain pressure ulcers stage and texture Renato V. Guadagnin, Levy Aniceto Santana, Rinaldo de Souza Neves Proceedings of Imta 5 2015 5th International Workshop on Image Mining Theory and Applications in Conjunction with the 10th Internatioanal Joint Conference on Computer Vision Imaging and Computer Graphics Theory and Applications Visigrapp 2015, 2015
Pressure ulcers attributes image mining to support therapeutic process: A research proposal Proceedings of the 4th International Workshop on Image Mining Theory and Applications Imta 2013 in Conjunction with Visigrapp 2013, 2013
A contribution to an image mining oriented geoprocessing Proceedings of the 2nd International Workshop on Image Mining Theory and Applications Imta 2009 in Conjunction with Visigrapp 2009, 2009
A proposal for automatic inference of pressure ulcers grade based on wound images and patient data Proceedings of the 1st International Workshop on Image Mining Theory and Applications Imta 2008 in Conjunction with Viisigrapp 2008, 2008