Laila Nahum

@fiocruz.br

René Rachou Institute - Fiocruz Minas
Oswaldo Cruz Foundation

I am an Evolutionary Biologist working on a broad range of scientific questions. Our research integrates different areas such as phylogenetics, molecular biodiversity, molecular evolution, function prediction, among others. Our teaching pedagogy applies methods to develop critical thinking and decision making. Our phylosophy is based on strong ethical values to support diversity and a more inclusive society. Together we may create a susteainable planet.

EDUCATION

I have a degree in Biological Sciences with a Bachelor's degree in Microbiology from the Federal University of Minas Gerais (UFMG), a Master's degree in Biochemistry, and a PhD. degree in Genetics from the University of São Paulo (USP). I completed three postdoctoral internships in the United States, two at the Marine Biological Laboratory (MBL, Woods Hole) and one at the Louisiana State University (LSU, Baton Rouge), working with functional genomics and molecular evolution, corresponding to 6.5 years of professional experience abroad.

RESEARCH, TEACHING, or OTHER INTERESTS

Multidisciplinary, Ecology, Evolution, Behavior and Systematics, Biochemistry, Genetics and Molecular Biology
1205

Scholar Citations

16

Scholar h-index

20

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Trypanosoma cruzi iron superoxide dismutases: insights from phylogenetics to chemotherapeutic target assessment
    J Hickson, LFA Athayde, TG Miranda, PAS Junior, AC Dos Santos, ...
    Parasites & vectors 15 (1), 194 , 2022
    2022
    Citations: 6
  • Reenacting the birth of a function: Functional divergence of HIUases and transthyretins as inferred by evolutionary and biophysical studies
    L Carrijo de Oliveira, MA Figueiredo Costa, N Goncalves Pedersolli, ...
    Journal of Molecular Evolution 89 (6), 370-383 , 2021
    2021
    Citations: 8
  • Perspectives From Systems Biology to Improve Knowledge of Leishmania Drug Resistance
    ECA Horácio, J Hickson, SMF Murta, JC Ruiz, LA Nahum
    Frontiers in cellular and infection microbiology 11, 653670 , 2021
    2021
    Citations: 13
  • Temperature dramatically shapes mosquito gene expression with consequences for mosquito–Zika virus interactions
    PG Ferreira, B Tesla, ECA Horácio, LA Nahum, MA Brindley, ...
    Frontiers in microbiology 11, 501089 , 2020
    2020
    Citations: 63
  • Helminths and cancers from the evolutionary perspective
    LLS Scholte, MA Pascoal-Xavier, LA Nahum
    Frontiers in Medicine 5, 90 , 2018
    2018
    Citations: 57
  • Evolutionary relationships among protein lysine deacetylases of parasites causing neglected diseases
    LLS Scholte, MM Mourao, FSM Pais, J Melesina, D Robaa, AC Volpini, ...
    Infection, Genetics and Evolution 53, 175-188 , 2017
    2017
    Citations: 32
  • Helminth secretomes reflect different lifestyles and parasitized hosts
    Y Cuesta-Astroz, FS de Oliveira, LA Nahum, G Oliveira
    International journal for parasitology 47 (9), 529-544 , 2017
    2017
    Citations: 60
  • Effectiveness of ITS and sub-regions as DNA barcode markers for the identification of Basidiomycota (Fungi)
    F Badotti, FS de Oliveira, CF Garcia, ABM Vaz, PLC Fonseca, LA Nahum, ...
    BMC microbiology 17 (1), 42 , 2017
    2017
    Citations: 311
  • Evolutionary analysis of the cystatin family in three Schistosoma species
    Y Cuesta-Astroz, LLS Scholte, FSM Pais, G Oliveira, LA Nahum
    Frontiers in Genetics 5, 206 , 2014
    2014
    Citations: 21
  • Lipopolysaccharide-induced inhibition of transcription of tlr4 in vitro is reversed by dexamethasone and correlates with presence of conserved NFκB binding sites
    CP Bonin, RYA Baccarin, K Nostell, LA Nahum, C Fossum, ...
    Biochemical and biophysical research communications 432 (2), 256-261 , 2013
    2013
    Citations: 26
  • The Schistosoma mansoni phylome: using evolutionary genomics to gain insight into a parasite’s biology
    LL Silva, M Marcet-Houben, LA Nahum, A Zerlotini, T Gabaldón, ...
    BMC genomics 13 (1), 617 , 2012
    2012
    Citations: 38
  • Proteome-wide evolutionary analysis reveals lineage-specific adaptations and improves funtional annotation of Schistosoma mansoni proteins.
    L SILVA, M MARCET-HOUBEN, L NAHUM, A ZERLOTINI, T GALBADÓN, ...
    2012
  • New Frontiers in Schistosoma Genomics and Transcriptomics
    LA Nahum, MM Mourao, G Oliveira
    Journal of Parasitology Research 2012 (1), 849132 , 2012
    2012
    Citations: 29
  • Eukaryotic Protein Kinases (ePKs) of the Helminth Parasite Schistosoma mansoni
    LF Andrade, LA Nahum, LGA Avelar, LL Silva, A Zerlotini, JC Ruiz, ...
    BMC genomics 12 (1), 215 , 2011
    2011
    Citations: 98
  • Identification of a fibrinogen-related protein (FBN9) gene in neotropical anopheline mosquitoes
    SB Oliveira, IC Ibraim, WP Tadei, JC Ruiz, LA Nahum, CFA Brito, ...
    Malaria journal 10 (1), 21 , 2011
    2011
    Citations: 9
  • Evolutionary histories of expanded peptidase families in Schistosoma mansoni
    LL Silva, M Marcet-Houben, A Zerlotini, T Gabaldón, G Oliveira, ...
    Memorias do Instituto Oswaldo Cruz 106, 864-877 , 2011
    2011
    Citations: 23
  • Functional Diversity of the Schistosoma mansoni Tyrosine Kinases
    LGA Avelar, LA Nahum, LF Andrade, G Oliveira
    Journal of Signal Transduction 2011 (1), 603290 , 2011
    2011
    Citations: 23
  • PROTEIN KINASES OF THE PARASITE SCHISTOSOMA MANSONI
    LF Andrade, L Avelar, J Ruiz, A Zerlotini, L Nahum, G Oliveira
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE 81 (5), 77-77 , 2009
    2009
  • Protein families reflect the metabolic diversity of organisms and provide support for functional prediction
    LA Nahum, S Goswami, MH Serres
    Physiological genomics 38 (3), 250-260 , 2009
    2009
    Citations: 8
  • Affiliations 8
    LA Nahum, S Goswami, MH Serres
    2009

MOST CITED SCHOLAR PUBLICATIONS

  • Effectiveness of ITS and sub-regions as DNA barcode markers for the identification of Basidiomycota (Fungi)
    F Badotti, FS de Oliveira, CF Garcia, ABM Vaz, PLC Fonseca, LA Nahum, ...
    BMC microbiology 17 (1), 42 , 2017
    2017
    Citations: 311
  • A functional update of the Escherichia coli K-12 genome
    MH Serres, S Gopal, LA Nahum, P Liang, T Gaasterland, M Riley
    Genome biology 2 (9), research0035. 1 , 2001
    2001
    Citations: 193
  • Eukaryotic Protein Kinases (ePKs) of the Helminth Parasite Schistosoma mansoni
    LF Andrade, LA Nahum, LGA Avelar, LL Silva, A Zerlotini, JC Ruiz, ...
    BMC genomics 12 (1), 215 , 2011
    2011
    Citations: 98
  • Sex identification of parrots, toucans, and curassows by PCR: perspectives for wild and captive population studies
    CY Miyaki, R Griffiths, K Orr, LA Nahum, SL Pereira, A Wajntal
    Zoo Biology: Published in affiliation with the American Zoo and Aquarium … , 1998
    1998
    Citations: 82
  • Temperature dramatically shapes mosquito gene expression with consequences for mosquito–Zika virus interactions
    PG Ferreira, B Tesla, ECA Horácio, LA Nahum, MA Brindley, ...
    Frontiers in microbiology 11, 501089 , 2020
    2020
    Citations: 63
  • Helminth secretomes reflect different lifestyles and parasitized hosts
    Y Cuesta-Astroz, FS de Oliveira, LA Nahum, G Oliveira
    International journal for parasitology 47 (9), 529-544 , 2017
    2017
    Citations: 60
  • Helminths and cancers from the evolutionary perspective
    LLS Scholte, MA Pascoal-Xavier, LA Nahum
    Frontiers in Medicine 5, 90 , 2018
    2018
    Citations: 57
  • The Schistosoma mansoni phylome: using evolutionary genomics to gain insight into a parasite’s biology
    LL Silva, M Marcet-Houben, LA Nahum, A Zerlotini, T Gabaldón, ...
    BMC genomics 13 (1), 617 , 2012
    2012
    Citations: 38
  • Divergence of function in sequence-related groups of Escherichia coli proteins
    LA Nahum, M Riley
    Genome Research 11 (8), 1375 , 2001
    2001
    Citations: 35
  • Evolutionary relationships among protein lysine deacetylases of parasites causing neglected diseases
    LLS Scholte, MM Mourao, FSM Pais, J Melesina, D Robaa, AC Volpini, ...
    Infection, Genetics and Evolution 53, 175-188 , 2017
    2017
    Citations: 32
  • New Frontiers in Schistosoma Genomics and Transcriptomics
    LA Nahum, MM Mourao, G Oliveira
    Journal of Parasitology Research 2012 (1), 849132 , 2012
    2012
    Citations: 29
  • Lipopolysaccharide-induced inhibition of transcription of tlr4 in vitro is reversed by dexamethasone and correlates with presence of conserved NFκB binding sites
    CP Bonin, RYA Baccarin, K Nostell, LA Nahum, C Fossum, ...
    Biochemical and biophysical research communications 432 (2), 256-261 , 2013
    2013
    Citations: 26
  • Diversification of Ramphastinae (Aves, Ramphastidae) prior to the Cretaceous/Tertiary boundary as shown by molecular clock of mtDNA sequences
    LA Nahum, SL Pereira, FM Campos Fernandes, S Russo Matioli, ...
    Genetics and Molecular Biology 26 (4), 411-418 , 2003
    2003
    Citations: 25
  • Evolutionary histories of expanded peptidase families in Schistosoma mansoni
    LL Silva, M Marcet-Houben, A Zerlotini, T Gabaldón, G Oliveira, ...
    Memorias do Instituto Oswaldo Cruz 106, 864-877 , 2011
    2011
    Citations: 23
  • Functional Diversity of the Schistosoma mansoni Tyrosine Kinases
    LGA Avelar, LA Nahum, LF Andrade, G Oliveira
    Journal of Signal Transduction 2011 (1), 603290 , 2011
    2011
    Citations: 23
  • Evolutionary analysis of the cystatin family in three Schistosoma species
    Y Cuesta-Astroz, LLS Scholte, FSM Pais, G Oliveira, LA Nahum
    Frontiers in Genetics 5, 206 , 2014
    2014
    Citations: 21
  • Adapting to a changing world: RAG genomics and evolution
    MM de Camargo, LA Nahum
    Human Genomics 2 (2), 132 , 2005
    2005
    Citations: 14
  • Perspectives From Systems Biology to Improve Knowledge of Leishmania Drug Resistance
    ECA Horácio, J Hickson, SMF Murta, JC Ruiz, LA Nahum
    Frontiers in cellular and infection microbiology 11, 653670 , 2021
    2021
    Citations: 13
  • Phylogenomics, protein family evolution, and the tree of life: an integrated approach between molecular evolution and computational intelligence
    LA Nahum, SL Pereira
    Applications of Computational Intelligence in Biology: Current Trends and … , 2008
    2008
    Citations: 13
  • Evolução dos genomas
    LA Nahum
    Biologia Molecular e Evolução, 82-96 , 2001
    2001
    Citations: 13