Lafon Pierre-Andre

RECENT SCHOLAR PUBLICATIONS

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease
P Lafon, ME Tsitokana, UG Alenda, YL Lian, CE Philibert, M Oosterlaken, ...
Advanced Science, e23791 , 2026
2026
Nanobodies: a new paradigm for brain disorder therapies
PA Lafon, L Prézeau, JP Pin, P Rondard
Trends in Pharmacological Sciences , 2025
2025
Citations: 2
Nanobody therapy rescues behavioural deficits of NMDA receptor hypofunction
M Oosterlaken, A Rogliardo, T Lipina, PA Lafon, ME Tsitokana, M Keck, ...
Nature 645 (8079), 262-270 , 2025
2025
Citations: 27
Non-canonical internalization mechanisms of mGlu receptors
M Cimadevila, J Liu, D Maurel, I Brabet, M Hoscar, J Drube, C Hoffmann, ...
Cell Reports 44 (8) , 2025
2025
Citations: 4
Chronic treatment with a metabotropic glutamate receptor 2 camelid nanobody accelerates amyloidogenesis in Alzheimer’s disease
PA Lafon, J Liu, V Perrier, P Rondard
Alzheimer's & Dementia 20, e088294 , 2024
2024
Fungicide residues aggravate cerebral amyloid angiopathy in an Alzheimer’s disease mouse model
PA Lafon, Y Wang, F Jeanneteau, C Desrumaux, V Perrier
Alzheimer's Association International Conference , 2024
2024
TrkB receptor interacts with mGlu 2 receptor and mediates antipsychotic-like effects of mGlu 2 receptor activation in the mouse
CE Philibert, C Disdier, PA Lafon, A Bouyssou, M Oosterlaken, S Galant, ...
Science Advances 10 (4), eadg1679 , 2024
2024
Citations: 14
Chronic potentiation of metabotropic glutamate receptor 2 with a nanobody accelerates amyloidogenesis in Alzheimer’s disease
PA Lafon, ME Tsitokana, U Alenda, CE Philibert, M Oosterlaken, ...
bioRxiv, 2024.01. 22.576777 , 2024
2024
Targeting the brain with single-domain antibodies: greater potential than stated so far?
ME Tsitokana, PA Lafon, L Prezeau, JP Pin, P Rondard
International Journal of Molecular Sciences 24 (3), 2632 , 2023
2023
Citations: 30
Nanobody-based sensors reveal a high proportion of mGlu heterodimers in the brain
J Meng, C Xu, PA Lafon, S Roux, M Mathieu, R Zhou, P Scholler, E Blanc, ...
Nature chemical biology 18 (8), 894-903 , 2022
2022
Citations: 57
Developmental exposure to the A6-pesticide causes changes in tyrosine hydroxylase gene expression, neurochemistry, and locomotor behavior in larval zebrafish
A Nasri, PA Lafon, A Mezni, P Clair, N Cubedo, E Mahmoudi, H Beyrem, ...
Toxicol Mech Methods 32 (8), 569-579 , 2021
2021
Citations: 1
L’environnement naturel modifié par l’homme : polluants environnementaux et maladies neuroévolutives liées à l’âge
V Perrier, J Torrent, L Salvador-Prince, PA Lafon
Environnement et vieillissement : partenaires ou adversaires ? , 2021
2021
Ethinylestradiol (EE2) residues from birth control pills impair nervous system development and swimming behavior of zebrafish larvae
A Nasri, A Mezni, PA Lafon, A Wahbi, N Cubedo, P Clair, AH Harrath, ...
Science of the Total Environment 770, 145272 , 2021
2021
Citations: 59
Prenatal exposure to low doses of fungicides corrupts neurogenesis in neonates
Y Wang, PA Lafon, L Salvador-Prince, AR Gines, F Trousse, J Torrent, ...
Environmental Research 195, 110829 , 2021
2021
Citations: 15
Fungicide Residues Exposure and Aggregation in a Mouse Model of Alzheimer’s Disease
PA Lafon, Y Wang, M Arango-Lievano, J Torrent, L Salvador-Prince, ...
Environmental health perspectives 128 (1), 017011 , 2020
2020
Citations: 49
Impact of pesticides on the amyloid aggregation in different models of neurodegenerative diseases
PA Lafon
< bound method Organization. get_name_with_acronym of< Organization: TEL … , 2019
2019
Impact des pesticides sur l'agrégation des amyloïdes dans différents modèles de maladies neurodégénératives
PA Lafon
Université Montpellier , 2019
2019
Pesticides i malalties neurodegeneratives.
PA Lafon, C Prévostel, V Perrier
Recull de conferencies 2016/Debats de recerca 10 - Chapter: 6 , 2019
2019
Low doses of bioherbicide favour prion aggregation and propagation in vivo
PA Lafon, T Imberdis, Y Wang, J Torrent, M Robitzer, E Huetter, ...
Scientific reports 8 (1), 8023 , 2018
2018
Citations: 19
Low doses of bioherbicide favour prion aggregation and propagation in vivo. Sci. Rep 8 (1): 8023, PMID: 29795181
PA Lafon, T Imberdis, Y Wang, J Torrent, M Robitzer, E Huetter
2018
Citations: 4

MOST CITED SCHOLAR PUBLICATIONS

Ethinylestradiol (EE2) residues from birth control pills impair nervous system development and swimming behavior of zebrafish larvae
A Nasri, A Mezni, PA Lafon, A Wahbi, N Cubedo, P Clair, AH Harrath, ...
Science of the Total Environment 770, 145272 , 2021
2021
Citations: 59
Nanobody-based sensors reveal a high proportion of mGlu heterodimers in the brain
J Meng, C Xu, PA Lafon, S Roux, M Mathieu, R Zhou, P Scholler, E Blanc, ...
Nature chemical biology 18 (8), 894-903 , 2022
2022
Citations: 57
Fungicide Residues Exposure and Aggregation in a Mouse Model of Alzheimer’s Disease
PA Lafon, Y Wang, M Arango-Lievano, J Torrent, L Salvador-Prince, ...
Environmental health perspectives 128 (1), 017011 , 2020
2020
Citations: 49
Targeting the brain with single-domain antibodies: greater potential than stated so far?
ME Tsitokana, PA Lafon, L Prezeau, JP Pin, P Rondard
International Journal of Molecular Sciences 24 (3), 2632 , 2023
2023
Citations: 30
Nanobody therapy rescues behavioural deficits of NMDA receptor hypofunction
M Oosterlaken, A Rogliardo, T Lipina, PA Lafon, ME Tsitokana, M Keck, ...
Nature 645 (8079), 262-270 , 2025
2025
Citations: 27
Low doses of bioherbicide favour prion aggregation and propagation in vivo
PA Lafon, T Imberdis, Y Wang, J Torrent, M Robitzer, E Huetter, ...
Scientific reports 8 (1), 8023 , 2018
2018
Citations: 19
Zeb family members and boundary cap cells underlie developmental plasticity of sensory nociceptive neurons
D Ohayon, S Venteo, C Sonrier, PA Lafon, A Garces, J Valmier, C Rivat, ...
Developmental Cell 33 (3), 343-350 , 2015
2015
Citations: 16
Prenatal exposure to low doses of fungicides corrupts neurogenesis in neonates
Y Wang, PA Lafon, L Salvador-Prince, AR Gines, F Trousse, J Torrent, ...
Environmental Research 195, 110829 , 2021
2021
Citations: 15
TrkB receptor interacts with mGlu 2 receptor and mediates antipsychotic-like effects of mGlu 2 receptor activation in the mouse
CE Philibert, C Disdier, PA Lafon, A Bouyssou, M Oosterlaken, S Galant, ...
Science Advances 10 (4), eadg1679 , 2024
2024
Citations: 14
Plasma cholesterol level determines in vivo prion propagation
V Perrier, T Imberdis, PA Lafon, M Cefis, Y Wang, E Huetter, JD Arnaud, ...
Journal of Lipid Research 58 (10), 1950-1961 , 2017
2017
Citations: 9
Non-canonical internalization mechanisms of mGlu receptors
M Cimadevila, J Liu, D Maurel, I Brabet, M Hoscar, J Drube, C Hoffmann, ...
Cell Reports 44 (8) , 2025
2025
Citations: 4
Low doses of bioherbicide favour prion aggregation and propagation in vivo. Sci. Rep 8 (1): 8023, PMID: 29795181
PA Lafon, T Imberdis, Y Wang, J Torrent, M Robitzer, E Huetter
2018
Citations: 4
Nanobodies: a new paradigm for brain disorder therapies
PA Lafon, L Prézeau, JP Pin, P Rondard
Trends in Pharmacological Sciences , 2025
2025
Citations: 2
Developmental exposure to the A6-pesticide causes changes in tyrosine hydroxylase gene expression, neurochemistry, and locomotor behavior in larval zebrafish
A Nasri, PA Lafon, A Mezni, P Clair, N Cubedo, E Mahmoudi, H Beyrem, ...
Toxicol Mech Methods 32 (8), 569-579 , 2021
2021
Citations: 1
Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease
P Lafon, ME Tsitokana, UG Alenda, YL Lian, CE Philibert, M Oosterlaken, ...
Advanced Science, e23791 , 2026
2026
Chronic treatment with a metabotropic glutamate receptor 2 camelid nanobody accelerates amyloidogenesis in Alzheimer’s disease
PA Lafon, J Liu, V Perrier, P Rondard
Alzheimer's & Dementia 20, e088294 , 2024
2024
Fungicide residues aggravate cerebral amyloid angiopathy in an Alzheimer’s disease mouse model
PA Lafon, Y Wang, F Jeanneteau, C Desrumaux, V Perrier
Alzheimer's Association International Conference , 2024
2024
Chronic potentiation of metabotropic glutamate receptor 2 with a nanobody accelerates amyloidogenesis in Alzheimer’s disease
PA Lafon, ME Tsitokana, U Alenda, CE Philibert, M Oosterlaken, ...
bioRxiv, 2024.01. 22.576777 , 2024
2024
L’environnement naturel modifié par l’homme : polluants environnementaux et maladies neuroévolutives liées à l’âge
V Perrier, J Torrent, L Salvador-Prince, PA Lafon
Environnement et vieillissement : partenaires ou adversaires ? , 2021
2021
Impact of pesticides on the amyloid aggregation in different models of neurodegenerative diseases
PA Lafon
< bound method Organization. get_name_with_acronym of< Organization: TEL … , 2019
2019