Javier Munoz Peralta

@biocrucesbizkaia.org

Principal Investigator
IIS Biobizkaia

RESEARCH, TEACHING, or OTHER INTERESTS

Biotechnology, Biochemistry, Molecular Biology, Cancer Research
8802

Scholar Citations

45

Scholar h-index

96

Scholar i10-index

RECENT SCHOLAR PUBLICATIONS

  • Defining the reference proteomes for small extracellular vesicles and non-vesicular components
    J Morales-Sanfrutos, J Etxeberria-Ugartemendia, O Barroso-Gomila, ...
    Nature Cell Biology, 1-18 , 2026
    2026
    Citations: 6
  • Polyamine-dependent metabolic shielding regulates alternative splicing
    A Zabala-Letona, M Pujana-Vaquerizo, B Martinez-Laosa, ...
    Nature, 1-10 , 2026
    2026
    Citations: 3
  • Identification of the PP1 interactome in human dental pulp: Insights for regenerative strategies
    A Kobrock, D Patrício, B Matos, E Zarzuela, J Muñoz, J Howl, PS Gomes, ...
    Cellular Signalling, 112132 , 2025
    2025
  • Proton pump inhibitor effect on esophageal protein signature of eosinophilic esophagitis, prediction, and evaluation of treatment response
    F Molina‐Jiménez, L Ugalde‐Triviño, L Arias‐González, E Armenteros, ...
    Allergy 79 (12), 3448-3463 , 2024
    2024
    Citations: 12
  • Epigenetic-based differentiation therapy for Acute Myeloid Leukemia
    E San José-Enériz, N Gimenez-Camino, O Rabal, L Garate, E Miranda, ...
    Nature Communications 15 (1), 5570 , 2024
    2024
    Citations: 13
  • FdeC expression regulates motility and adhesion of the avian pathogenic Escherichia coli strain IMT5155
    A Aleksandrowicz, RB Kjærup, K Grzymajło, FG Martinez, J Muñoz, ...
    Veterinary research 55 (1), 70 , 2024
    2024
    Citations: 9
  • Effect of an immune challenge and two feed supplements on broiler chicken individual breast muscle protein synthesis rate
    J Peinado-Izaguerri, A Corbishley, E Zarzuela, B Pina-Beltrán, F Riva, ...
    Journal of proteomics 299, 105158 , 2024
    2024
    Citations: 7
  • A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation
    P Ubieto-Capella, P Ximénez-Embún, D Giménez-Llorente, A Losada, ...
    Cell reports 43 (4) , 2024
    2024
    Citations: 8
  • Hepatic nutrient and hormone signaling to mTORC1 instructs the postnatal metabolic zonation of the liver
    AB Plata-Gómez, L de Prado-Rivas, A Sanz, N Deleyto-Seldas, F García, ...
    Nature communications 15 (1), 1878 , 2024
    2024
    Citations: 19
  • FdeC expression regulates motility and adhesion of the avian pathogenic Escherichia coli strain IMT5155
    KR Brødsgaard, K Grzymajło, FG Martinez, J Muñoz, D Borowska, S Sives, ...
    Veterinary Research 55 , 2024
    2024
    Citations: 1
  • An allosteric switch between the activation loop and a c-terminal palindromic phospho-motif controls c-Src function
    HN Cuesta-Hernández, J Contreras, P Soriano-Maldonado, ...
    Nature communications 14 (1), 6548 , 2023
    2023
    Citations: 18
  • Proteomic analysis of the esophageal epithelium reveals key features of eosinophilic esophagitis pathophysiology
    F Molina‐Jiménez, L Ugalde‐Triviño, L Arias‐González, ...
    Allergy 78 (10), 2732-2744 , 2023
    2023
    Citations: 22
  • DLST mutations in pheochromocytoma and paraganglioma cause proteome hyposuccinylation and metabolic remodeling
    S Mellid, F García, LJ Leandro‐García, A Díaz‐Talavera, ...
    Cancer Communications 43 (7), 838-843 , 2023
    2023
    Citations: 11
  • NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation
    I Cobo, S Paliwal, C Bodas, I Felipe, J Melià-Alomà, A Torres, ...
    Nature Communications 14 (1), 3761 , 2023
    2023
    Citations: 14
  • Ubiquitin proteomics identifies RNA polymerase I as a target of the Smc5/6 complex
    E Ibars, J Codina-Fabra, G Bellí, C Casas, M Tarrés, R Sole-Soler, ...
    Cell Reports 42 (5) , 2023
    2023
    Citations: 16
  • A novel dynamic proteomics approach for the measurement of broiler chicken protein fractional synthesis rate
    J Peinado‐Izaguerri, E Zarzuela, M McLaughlin, AC Small, F Riva, ...
    Rapid Communications in Mass Spectrometry 37 (10), e9497 , 2023
    2023
    Citations: 8
  • Decoding protein methylation function with thermal stability analysis
    C Sayago, J Sánchez-Wandelmer, F García, B Hurtado, V Lafarga, ...
    Nature Communications 14 (1), 3016 , 2023
    2023
    Citations: 11
  • Peroxiredoxin 2 is required for the redox mediated adaptation to exercise
    Q Xia, JC Casas-Martinez, E Zarzuela, J Muñoz, A Miranda-Vizuete, ...
    Redox biology 60, 102631 , 2023
    2023
    Citations: 41
  • Beneficial effects of mifepristone treatment in patients with breast cancer selected by the progesterone receptor isoform ratio: results from the MIPRA trial
    A Elía, L Saldain, SI Vanzulli, LA Helguero, CA Lamb, V Fabris, ...
    Clinical Cancer Research 29 (5), 866-877 , 2023
    2023
    Citations: 44
  • Novel epigenetic based differentiation therapy for Acute Myeloid Leukemia
    E San José-Enériz, N Gimenez-Camino, O Rabal, L Garate, E Miranda, ...
    2023

MOST CITED SCHOLAR PUBLICATIONS

  • Next-generation proteomics: towards an integrative view of proteome dynamics
    AFM Altelaar, J Munoz, AJR Heck
    Nature Reviews Genetics 14 (1), 35-48 , 2013
    2013
    Citations: 1026
  • The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+ 4’cell markers
    J Muñoz, DE Stange, AG Schepers, M van de Wetering, BK Koo, ...
    The EMBO Journal , 2012
    2012
    Citations: 959
  • STAT3 labels a subpopulation of reactive astrocytes required for brain metastasis
    N Priego, L Zhu, C Monteiro, M Mulders, D Wasilewski, W Bindeman, ...
    Nature medicine 24 (7), 1024-1035 , 2018
    2018
    Citations: 498
  • Phosphorylation dynamics during early differentiation of human embryonic stem cells
    D Van Hoof, J Muñoz, SR Braam, MWH Pinkse, R Linding, AJR Heck, ...
    Cell stem cell 5 (2), 214-226 , 2009
    2009
    Citations: 395
  • Cellular senescence is immunogenic and promotes antitumor immunity
    I Marin, O Boix, A Garcia-Garijo, I Sirois, A Caballe, E Zarzuela, I Ruano, ...
    Cancer discovery 13 (2), 410-431 , 2023
    2023
    Citations: 333
  • Small extracellular vesicles are key regulators of non-cell autonomous intercellular communication in senescence via the interferon protein IFITM3
    M Borghesan, J Fafián-Labora, O Eleftheriadou, P Carpintero-Fernández, ...
    Cell reports 27 (13), 3956-3971. e6 , 2019
    2019
    Citations: 307
  • Genome-wide characterization of the routes to pluripotency
    SMI Hussein, MC Puri, PD Tonge, M Benevento, AJ Corso, JL Clancy, ...
    Nature 516 (7530), 198-206 , 2014
    2014
    Citations: 252
  • mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer
    A Zabala-Letona, A Arruabarrena-Aristorena, N Martín-Martín, ...
    Nature 547 (7661), 109-113 , 2017
    2017
    Citations: 236
  • Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
    S García-Silva, A Benito-Martín, L Nogués, A Hernández-Barranco, ...
    Nature cancer 2 (12), 1387-1405 , 2021
    2021
    Citations: 199
  • Whole-body imaging of lymphovascular niches identifies pre-metastatic roles of midkine
    D Olmeda, D Cerezo-Wallis, E Riveiro-Falkenbach, PC Pennacchi, ...
    Nature 546 (7660), 676-680 , 2017
    2017
    Citations: 193
  • USP7 is a SUMO deubiquitinase essential for DNA replication
    E Lecona, S Rodriguez-Acebes, J Specks, AJ Lopez-Contreras, I Ruppen, ...
    Nature structural & molecular biology 23 (4), 270-277 , 2016
    2016
    Citations: 177
  • The quantitative proteomes of human-induced pluripotent stem cells and embryonic stem cells
    J Munoz, TY Low, YJ Kok, A Chin, CK Frese, V Ding, A Choo, AJR Heck
    Molecular Systems Biology 7 (1) , 2011
    2011
    Citations: 166
  • Mutant glucocerebrosidase impairs α-synuclein degradation by blockade of chaperone-mediated autophagy
    SH Kuo, I Tasset, MM Cheng, A Diaz, MK Pan, OJ Lieberman, SJ Hutten, ...
    Science Advances 8 (6), eabm6393 , 2022
    2022
    Citations: 161
  • Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant state
    D Cerezo-Wallis, M Contreras-Alcalde, K Troulé, X Catena, C Mucientes, ...
    Nature medicine 26 (12), 1865-1877 , 2020
    2020
    Citations: 160
  • Use of extracellular vesicles from lymphatic drainage as surrogate markers of melanoma progression and BRAF V600E mutation
    S García-Silva, A Benito-Martín, S Sánchez-Redondo, ...
    Journal of Experimental Medicine 216 (5), 1061-1070 , 2019
    2019
    Citations: 150
  • A proteomic characterization of factors enriched at nascent DNA molecules
    AJ Lopez-Contreras, I Ruppen, M Nieto-Soler, M Murga, ...
    Cell reports 3 (4), 1105-1116 , 2013
    2013
    Citations: 149
  • DAZL limits pluripotency, differentiation, and apoptosis in developing primordial germ cells
    HH Chen, M Welling, DB Bloch, J Muñoz, E Mientjes, X Chen, C Tramp, ...
    Stem cell reports 3 (5), 892-904 , 2014
    2014
    Citations: 124
  • Targeting tumor mitochondrial metabolism overcomes resistance to antiangiogenics
    P Navarro, MJ Bueno, I Zagorac, T Mondejar, J Sanchez, S Mouron, ...
    Cell reports 15 (12), 2705-2718 , 2016
    2016
    Citations: 116
  • The lysosomal proteome of senescent cells contributes to the senescence secretome
    M Rovira, R Sereda, D Pladevall‐Morera, V Ramponi, I Marin, M Maus, ...
    Aging cell 21 (10), e13707 , 2022
    2022
    Citations: 115
  • CD24 tracks divergent pluripotent states in mouse and human cells
    N Shakiba, CA White, YY Lipsitz, A Yachie-Kinoshita, PD Tonge, ...
    Nature communications 6 (1), 7329 , 2015
    2015
    Citations: 100