Food Science, Agricultural and Biological Sciences, Biotechnology, Microbiology
71
Scopus Publications
3354
Scholar Citations
33
Scholar h-index
54
Scholar i10-index
Scopus Publications
Unlocking the Potential of Precision Food Processing: Industrial, Biotechnological, and Nutritional Perspectives Gebremichael Gebremedhin Hailu, Anand Kumar, Imran Khan, Ramachandran Chelliah, Sun‐Il Choi, Ok‐Hwan Lee, Deog‐Hwan Oh, Shucheng Liu, Shuai Wei Comprehensive Reviews in Food Science and Food Safety, 2026 Precision food processing (PFP) is an emerging integrated approach designed to address critical challenges in modern food production, including rising demands for nutrition, safety, sustainability, and quality. By harmonizing precision agriculture, processing, and analysis, PFP optimizes every stage of the food chain, from farm to fork. The current review explores recent advancements in PFP, placing emphasis on its industrial, biotechnological, and nutritional aspects to underscore its transformative potential. Precision agriculture optimizes resource use and crop production through advanced technologies, establishing the foundation for PFP by enhancing raw material quality, yield, and efficiency. In the food industry, PFP subsequently introduces effective optimization techniques, novel processing methods, and robotics to enhance process efficiency and product consistency. To ensure effectiveness across all PFP stages, precision analysis is applied to monitor ingredients, processes, and final products in real‐time, guaranteeing safety, consistency, and compliance with nutritional targets. Biotechnological advancements, such as genetic engineering, genome‐editing, and precision fermentation, have enhanced the efficiency of ingredient production and improved the capabilities of microbial strains. Nutritionally, PFP preserves nutrients through advanced processing methods and enables targeted biofortification. By integrating these perspectives, PFP offers a holistic solution to the production of safe, sustainable, and nutritious foods, addressing global food system challenges. This review highlights these advancements, identifies interconnections across stages, and underlines the potential of PFP in shaping the future of food production.
Nanobiotechnological interventions for sustainable food supplies and agricultural production Sara Najeeb, Sumaira Miskeen, Muhammad Jahangir, Imran Khan Expanding Nanobiotechnology Applications and Commercialization, 2025 The globe is encountering significant challenges due to growing demand for safe and adequate food supplies and the continued environmental harm caused by conventional agriculture. To address these problems and the increasing global population, food production must embrace more environmentally friendly methods. Nanobiotechnology offers a promising solution in this regard by enabling the development of nutritious, safer, and superior functional food products that with improved shelf life for both perishable and semi-perishable items. Nanobiotechnology offers advantages over traditional food processing techniques in enhancing shelf life, preventing contamination, and elevating overall food quality. Modifying the size and surface characteristics of food nanomaterials enhances flavor, bioavailability, texture, and stability. The incorporation of nanocoating, nanobiosensors, and nanocomposites in intelligent food packaging facilitates quality monitoring and freshness preservation. Additionally, ongoing extensive research examines the effects of nanomaterials on biological systems. In agriculture, nanobiotechnology has significant potential for improving efficiency and productivity through techniques such as nanofertilizer and nanosensors which can increase crop yield and reduce waste. Thus, chapter underscores the benefits of nanobiotechnology for both food production and agriculture and its potential to create more sustainable and environmentally friendly solutions for the world's food supply needs, ensuring a safe and adequate food supply for future generations.
Metal nanoparticles in agriculture Imran Khan, Sara Najeeb, Sumaira Miskeen, Muhammad Jahangir Expanding Nanobiotechnology Applications and Commercialization, 2025 The significance of developing and using green nanoparticles (NPs) has come into greater emphasis as the importance of maintaining a sustainable environment has gotten more attention. Metal nanoparticles (MNPs) have drawn a lot of attention among different types of NPs. In recent years, the research community has increasingly focused on the utilization of MNPs for promoting sustainable agricultural production and enhancing food security. To minimize metal salts and stabilize MNPs, variety of biological components has been used in replacement of toxic chemicals, i.e., green synthesis methods have incorporated nanobiotechnological advancements. MNPs synthesized through green methods find various applications in the agricultural sector, such as promoting plant growth, controlling plant diseases, and managing pests and insects, among others. In food industry MNPs were used for increasing shelf life, active food packaging, protecting from food spoilage, and many other purposes. A comprehensive review has been conducted within the broader context of recent studies, focusing on the relevance of green-synthesized MNPs, particularly in the context of sustainable food security and agriculture.
Nutraceutical Potential of Bidens Species Zakir Ullah, Banzeer Ahsan Abbasi, Javed Iqbal, Shumaila Ijaz, Mamoona Munir, Tabassum Yaseen, Sobia Kanwal, Tariq Mahmood, Sayed Afzal Shah, Imran Khan, Shobana Sampath Genus Bidens Chemistry and Pharmacology, 2025
Anti-inflammatory and Analgesic Activity of Bidens Species Shumaila Ijaz, Banzeer Ahsan Abbasi, Javed Iqbal, Zakir Ullah, Tabassum Yaseen, Mamoona Munir, Sobia Kanwal, Tariq Mahmood, Sayed Afzal Shah, Imran Khan, Shobana Sampath Genus Bidens Chemistry and Pharmacology, 2025
Characterization and genomic analysis of a Herelleviridae bacteriophage UHP46 infecting mastitis-causing Staphylococcus aureus Sara Najeeb, Imran Khan, Javed Muhammad, Muhammad Jahangir, Iqbal Ahmad Alvi, Anza Abbas, Aman Ullah, Arif Ullah, Wajiha Sajjad, Hashir Khan, Amjad Khan Frontiers in Microbiology, 2025 BackgroundMastitis is a widespread disease on a global scale, significantly impacting the dairy industry. Mastitis in dairy cattle is caused by over 150 different bacteria, with Staphylococcus aureus (S. aureus) playing a significant role in financial losses, problems with animal welfare, and challenges with food safety. Phage treatment is thus being investigated as an effective replacement for reducing contaminants and illnesses caused by bacteria. In this study, we identified a phage UHP46, that effectively targets mastitis-causing S. aureus.MethodsS. aureus S46 was used to screen for the wastewater lytic phages. The isolated lytic phage UHP46, which formed clear plaques and spots, was further characterized.ResultsPhage UHP46, belonging to the Herelleviridae family, forms clear, circular plaques in bacterial lawn. UHP46 showed stability under various range of temperature and pH levels, with maximum activity observed at pH 7 and temperature 37°C. Genomic analysis revealed that phage UHP46 is a dsDNA virus with an approximate genome size of 139,731 bp, and it encodes 72 proteins with known functions and 136 hypothetical proteins. One-step growth curve analysis indicated latent period of approximately 20 mins and burst size of about 27 progeny/cell. In organic stability test, UHP46 showed stability in DMSO and acetone. Furthermore, it effectively inhibited S. aureus growth for up to 16 h, suggesting its suitability for therapeutic applications against S. aureus infections.ConclusionThese findings suggest that phage UHP46 could serve as a promising alternative to antibiotics for managing S. aureus- induced mastitis, contributing to dairy production and improved animal health.
Preparation and quality evaluation of mixed fruit jam made from natural and artificial sweetener Muhammad Haroon, Imran Khan, Afaf Ejaz, Muhammad Afzaal, Farhan Saeed, Muhammad Umar Farooq, Maryam Ehsan, Faiyaz Ahmed, Noor Akram, Gebremichael Gebremedhin Hailu Efood, 2024 In this study nutritionally enriched apple and date jam was developed by replacing sugar with natural and artificial sweeteners stevia and sorbitol. Three different types of samples were prepared. Sample T1 was prepared by using stevia as a sweetener agent. Sample T2 was prepared by using sorbitol as a sweetener agent. Sample T3 was prepared by using a mixture of stevia and sorbitol as sweetener agents. Standard apple jam was used as a control sample labeled as T4 and was used for comparison analysis. The developed product was analyzed by physiochemical analysis and sensory evaluation. Microbial analysis was done to study the shelf life study of the developed product. The study showed that stevia and sorbitol could be used for jam preparation. Sample T3 also showed intermediate values of acidity and pH as 4.14 and 1.90, respectively, moreover, total soluble solids (TSS) was observed as 65.16 °Brix, T3 also showed an intermediate level of energy values. Sample T3 having sorbitol and stevia sweetener agents had the highest rate of overall acceptability. Storage studies of all samples show that with the passage of time all sensory characteristics of all treatments decreased.
Physicochemical and nutritional profiles of wild adlay (Coix lacryma-jobi Linn) accessions by GC, FTIR, and spectrophotometer Rauf Ahmad, Muhammad Liaquat, Shehla Sammi, Jehad S. Al-Hawadi, Muhammad Jahangir, Amer Mumtaz, Imran Khan, Mohammad K. Okla, Ibrahim A. Alaraidh, Hamada AbdElgawad, Ke Liu, Matthew Tom Harrison, Shah Saud, Shah Hassan, Taufiq Nawaz, Mo Zhu, Haitao Liu, Muhammad Adnan, Abdul Sadiq, Tanzeel Ur Rahman, Basem H. Asghari, Shah Fahad Food Chemistry X, 2024 Purpose of current study was to determine physicochemical, triglyceride composition, and functional groups of wild adlay accessions (brown, black, yellow, grey, green, off white, and purple) to find out its scope as cereal crop. Triglycerides, minerals and functional groups were determined through Gas chromatography, spectrophotometer and Fourier Transform Infrared (FTIR) spectrophotometer respectively. Results revealed variation among bulk densities, specific densities, percent empty spaces, and corresponding grain counts per 10 g of sample are useful in distinguishing brown, black, yellow, grey, green, off white, and purple wild adlay accessions. Specific density and grain count per 10 g sample was significantly related. No statistical relationship exists among the pronounced physical characteristics. Brown adlay expressed the highest protein, fat, and fiber contents 15.82%, 4.76% and 2.37% respectively. Protein, fat, ash, and fiber percent contents were found comparable to cultivated adlay. Spectrophotometric analysis revealed macro elements including phosphorus, potassium, calcium, and sodium in the range 0.3% - 2.2% and micro elements boron, iron, copper, zinc, and manganese in the range 1.6 mg/kg - 20.8 mg/kg. Gas chromatography showed polyunsaturated fatty acids (PUFA) constitute the primary fraction (39% ± 7.2) of wild adlay triglycerides. Linoleic and palmitic acids were present as prominent fatty acids, 43.5% ±1.4 and 26.3% ±1.4 respectively. Infra-red frequencies distinguished functional groups in narrow band and fingerprint region of protein in association with out of plane region leading to structural differences among adlay accessions. Comparison of major distinguishing vibrational frequencies among different flours indicated black adlay containing highest functional groups appeared promising for varietal development.
Xanthine oxidase inhibitory study of eight structurally diverse phenolic compounds Arshad Mehmood, Jiayi Li, Ashfaq Ur Rehman, Rovina Kobun, Inam U Llah, Imran Khan, Fayez Althobaiti, Sarah Albogami, Muhammad Usman, Fahad Alharthi, Mohamed Mohamed Soliman, Sanabil Yaqoob, Kanza Aziz Awan, Liang Zhao, Lei Zhao Frontiers in Nutrition, 2022
A review on the application of bioinformatics tools in food microbiome studies Ramachandran Chelliah, Eric Banan-MwineDaliri, Imran Khan, Shuai Wei, Fazle Elahi, Su-Jung Yeon, Vijayalakshmi Selvakumar, Fred Kwame Ofosu, Momna Rubab, Hum Hun Ju, Harikrishna Reddy Rallabandi, Inamul Hasan Madar, Ghazala Sultan, Deog Hwan Oh Briefings in Bioinformatics, 2022
Sublethal Injury Adaptation in Foodborne Pathogens Imran Khan, Shehla Sammi, Bashir Ahmad, Inam Ullah, Sumaira Miskeen, Muhammad Liaquat, Muhammad Jahangir Stress Responses of Foodborne Pathogens, 2022
Molecular mechanisms of anticancer activities of polyphyllin VII Bashir Ahmad, Shafiq Ur Rehman, Azizullah Azizullah, Muhammad Fiaz Khan, Syed Riaz Ud Din, Manzoor Ahmad, Ashraf Ali, Naeem Tahir, Nasir Azam, Yaser Gamallat, Khalil Ur Rahman, Muhsin Ali, Mohammad Safi, Imran Khan, Samina Qamer, Deog‐Hwan Oh Chemical Biology and Drug Design, 2021
Synthesis of nanomaterials for biofuel and bioenergy applications Jayachandran Krishna, Ayyappasamy Sudalaiyadum Perumal, Imran Khan, Ramachandran Chelliah, Shuai Wei, Caroline Mercy Andrew Swamidoss, Deog-Hwan Oh, B. Bharathiraja Nanomaterials Application in Biofuels and Bioenergy Production Systems, 2021
Liposomes for Drug Delivery: Progress and Problems Ramachandran Chelliah, Imran Khan, Eric Banan-Mwine Daliri, L. Tamizhini, K. S. Pravitha, Mahamuda Begum, Kandasamy Saravanakumar, Myeong-Hyeon Wang, Deog Hwan Oh Nanotechnology in the Life Sciences, 2021
Antibacterial, antifungal, phytotoxic, antioxidant and hemagglutination activities of organic fractions of Arisaema tortuosum Pakistan Journal of Pharmaceutical Sciences, 2016
Larvicidal, insecticidal, brine shrimp cytotoxicity and anti-oxidant activities of Diospyros kaki (L.) reported from Pakistan Pakistan Journal of Pharmaceutical Sciences, 2015
N-Methylpyrrolidine-1-carbothioamide M. Naveed Umar, M. Nawaz Tahir, Mohammad Shoaib, Akbar Ali, Imran Khan Acta Crystallographica Section E Structure Reports Online, 2012
Screening of antibacterial activity of medicinal plants International Journal of Pharmaceutical Sciences Review and Research, 2012
Reducing allergenicity of Trachinotus ovatus parvalbumin: Insights into digestibility and IgE-binding ability after dense phase CO₂ treatment H Qiu, W Duan, R Liang, W Hu, I Khan, S Liu, S Wei International Journal of Biological Macromolecules, 147548 , 2025 2025 Citations: 2
Characterization and genomic analysis of a Herelleviridae bacteriophage UHP46 infecting mastitis-causing Staphylococcus aureus S Najeeb, I Khan, J Muhammad, M Jahangir, IA Alvi, A Abbas, A Ullah, ... Frontiers in Microbiology 16, 1496919 , 2025 2025 Citations: 6
Preparation and quality evaluation of mixed fruit jam made from natural and artificial sweetener M Haroon, I Khan, A Ejaz, M Afzaal, F Saeed, MU Farooq, M Ehsan, ... EFood 5 (6), e70022 , 2024 2024 Citations: 10
Bactericidal efficacy of plasma-activated water against Vibrio parahaemolyticus on Litopenaeus vannamei H Zhang, J Wei, H Xv, I Khan, Q Sun, X Zhao, J Gao, S Liu, S Wei Frontiers in Nutrition 11, 1365282 , 2024 2024 Citations: 17
Antibacterial mechanism of slightly acidic electrolyzed water against Pseudomonas arsenicoxydans A1 from greater amberjack (Seriola dumerili) H Zhong, Y Liu, S Wei, I Khan, Q Sun, Z Wang, Z Han, Y Liu, DH Oh, S Liu Lwt 194, 115814 , 2024 2024 Citations: 17
Berberis lycium : A Miracle Medicinal Plant with Multifaceted Health Benefits B Ahmad, A Murshed, MY Zaky, I Khan, F Rahman, MH Abdellattif, G Liu, ... Journal of Food Quality 2024 (1), 3152456 , 2024 2024 Citations: 13
Phytochemical Profiling and Therapeutic Potential of Abelmoschus esculentus Fruit Extracts: Insights Into Antidiabetic Potential in In Vitro and In Vivo Experiments H Ullah, T Jan, B Ahmad, T Nawaz, I Khan, K Ahmad, AU Rehman, ... Journal of Food Quality 2024 (1), 7096736 , 2024 2024 Citations: 6
Impact of salicylic acid and calcium chloride on quality attributes of peach stored at refrigeration temperature N Khalid, S Sammi, S Miskeen, I Khan, M Liaquat, K Anwar, A Khan, ... Food Science and Biotechnology 32 (9), 1281 , 2023 2023 Citations: 10
Physicochemical parameters and nutritional profile of back and abdomen muscle of fresh golden pompano (Trachinotus ovatus) and hybrid grouper (Epinephelus lanceolatus … A Ali, J Wang, I Khan, S Wei, Q Sun, Q Xia, Z Wang, Z Han, S Liu Food Science & Nutrition 11 (2), 1024-1039 , 2023 2023 Citations: 9
NMR-Based Metabolomics for Geographical Discrimination of Adhatoda vasica Leaves M Jahangir, IB Abdel Farid, R Verpoorte, I Khan, J Peng Plants 12 (3), 453 , 2023 2023 Citations: 7
Research progress on nutritional value, preservation and processing of fish—A review A Ali, S Wei, A Ali, I Khan, Q Sun, Q Xia, Z Wang, Z Han, Y Liu, S Liu Foods 11 (22), 3669 , 2022 2022 Citations: 122
Xanthine oxidase inhibitory study of eight structurally diverse phenolic compounds A Mehmood, J Li, AU Rehman, R Kobun, IU Llah, I Khan, F Althobaiti, ... Frontiers in nutrition 9, 966557 , 2022 2022 Citations: 41
Sublethal Injury Adaptation in Foodborne Pathogens I Khan, S Sammi, B Ahmad, I Ullah, S Miskeen, M Liaquat, M Jahangir Stress Responses of Foodborne Pathogens, 517-536 , 2022 2022 Citations: 4
A review on the application of bioinformatics tools in food microbiome studies R Chelliah, E Banan-MwineDaliri, I Khan, S Wei, F Elahi, SJ Yeon, ... Briefings in Bioinformatics 23 (2), bbac007 , 2022 2022 Citations: 34
Molecular mechanisms of anticancer activities of polyphyllin VII B Ahmad, SU Rehman, A Azizullah, MF Khan, SRU Din, M Ahmad, A Ali, ... Chemical Biology & Drug Design 97 (4), 914-929 , 2021 2021 Citations: 36
Comparable plasma lipid changes in patients with high-grade cervical intraepithelial neoplasia and patients with cervical cancer M Nam, SS Seo, S Jung, SY Jang, J Lee, M Kwon, I Khan, DH Ryu, ... Journal of proteome research 20 (1), 740-750 , 2020 2020 Citations: 35
Proinflammatory dietary intake is associated with increased risk of metabolic syndrome and its components: results from the population-based prospective study I Khan, M Kwon, N Shivappa, J R. Hébert, MK Kim Nutrients 12 (4), 1196 , 2020 2020 Citations: 37
Positive association of dietary inflammatory index with incidence of cardiovascular disease: findings from a Korean population-based prospective study I Khan, M Kwon, N Shivappa, JR Hébert, MK Kim Nutrients 12 (2), 588 , 2020 2020 Citations: 37
Nanoencapsulation of plant-based oils and its applications in food and food packaging bioavailability R Chelliah, SR Ramakrishnan, I Khan, P Ganesan, DH Oh, JH Kwon Food Applications of Nanotechnology, 383-420 , 2019 2019 Citations: 1
Application of nanoparticles in food preservation and food processing J Prakash, K Vignesh, T Anusuya, T Kalaivani, C Ramachandran, ... 한국식품위생안전성학회지 34 (4), 317-324 , 2019 2019 Citations: 33
MOST CITED SCHOLAR PUBLICATIONS
Electrolyzed water as a novel sanitizer in the food industry: current trends and future perspectives SME Rahman, I Khan, DH Oh Comprehensive Reviews in Food Science and Food Safety 15 (3), 471-490 , 2016 2016 Citations: 478
Hurdle technology: A novel approach for enhanced food quality and safety–A review I Khan, CN Tango, S Miskeen, BH Lee, DH Oh Food control 73, 1426-1444 , 2017 2017 Citations: 327
Integration of nisin into nanoparticles for application in foods I Khan, DH Oh Innovative Food Science & Emerging Technologies 34, 376-384 , 2016 2016 Citations: 162
Cytotoxic and anthelmintic potential of crude saponins isolated from Achillea Wilhelmsii C. Koch and Teucrium Stocksianum boiss N Ali, SWA Shah, I Shah, G Ahmed, M Ghias, I Khan BMC complementary and alternative medicine 11 (1), 106 , 2011 2011 Citations: 141
Research progress on nutritional value, preservation and processing of fish—A review A Ali, S Wei, A Ali, I Khan, Q Sun, Q Xia, Z Wang, Z Han, Y Liu, S Liu Foods 11 (22), 3669 , 2022 2022 Citations: 122
Nanobiotechnology and its applications in drug delivery system: a review I Khan, M Khan, MN Umar, DH Oh IET nanobiotechnology 9 (6), 396-400 , 2015 2015 Citations: 118
Slightly acidic electrolyzed water combined with chemical and physical treatments to decontaminate bacteria on fresh fruits CN Tango, I Khan, PFN Kounkeu, R Momna, MS Hussain, DH Oh Food microbiology 67, 97-105 , 2017 2017 Citations: 113
Acute toxicity, brine shrimp cytotoxicity and relaxant activity of fruits of callistemon citrinus curtis N Ali, G Ahmed, SW Ali Shah, I Shah, M Ghias, I Khan BMC complementary and alternative medicine 11 (1), 99 , 2011 2011 Citations: 91
Microbiological quality and safety of fresh fruits and vegetables at retail levels in Korea CN Tango, S Wei, I Khan, MS Hussain, PFN Kounkeu, J Park, S Kim, ... Journal of food science 83 (2), 386-392 , 2018 2018 Citations: 87
Inactivation of bacterial pathogens on lettuce, sprouts, and spinach using hurdle technology PFK Ngnitcho, I Khan, CN Tango, MS Hussain, DH Oh Innovative Food Science & Emerging Technologies 43, 68-76 , 2017 2017 Citations: 80
LC/MS-Based Polar Metabolite Profiling Identified Unique Biomarker Signatures for Cervical Cancer and Cervical Intraepithelial Neoplasia Using Global and Targeted Metabolomics Imran Khan, Miso Nam, Minji Kwon, Sang-soo Seo, Sunhee Jung, Ji Soo Han ... Cancers 11 (4), 511 , 2019 2019 Citations: 79
Evaluation of nisin-loaded chitosan-monomethyl fumaric acid nanoparticles as a direct food additive I Khan, CN Tango, S Miskeen, DH Oh Carbohydrate polymers 184, 100-107 , 2018 2018 Citations: 71
Chitosan grafted monomethyl fumaric acid as a potential food preservative I Khan, S Ullah, DH Oh Carbohydrate Polymers 152, 87-96 , 2016 2016 Citations: 71
Anthelmintic and relaxant activities of Verbascum Thapsus Mullein N Ali, SW Ali Shah, I Shah, G Ahmed, M Ghias, I Khan, W Ali BMC complementary and alternative medicine 12 (1), 29 , 2012 2012 Citations: 68
Synthesis, characterization and evaluation of lecithin-based nanocarriers for the enhanced pharmacological and oral pharmacokinetic profile of amphotericin B I Javed, SZ Hussain, I Ullah, I Khan, M Ateeq, G Shahnaz, H ur Rehman, ... Journal of materials chemistry B 3 (42), 8359-8365 , 2015 2015 Citations: 65
Development of antimicrobial edible coating based on modified chitosan for the improvement of strawberries shelf life I Khan, CN Tango, R Chelliah, DH Oh Food Science and Biotechnology 28 (4), 1257-1264 , 2019 2019 Citations: 60
Evaluation of the efficacy of nisin-loaded chitosan nanoparticles against foodborne pathogens in orange juice EH Lee, I Khan, DH Oh Journal of food science and technology 55 (3), 1127-1133 , 2018 2018 Citations: 59
Antibacterial activity of honey in north-west Pakistan against select human pathogens AT Khalil, I Khan, K Ahmad, YA Khan, J Khan, ZK Shinwari Journal of Traditional Chinese Medicine 34 (1), 86-89 , 2014 2014 Citations: 57
Modeling the effect of pH, water activity, and ethanol concentration on biofilm formation of Staphylococcus aureus CN Tango, S Akkermans, MS Hussain, I Khan, J Van Impe, YG Jin, DH Oh Food microbiology 76, 287-295 , 2018 2018 Citations: 56
Evaluation of antileishmanial, antibacterial and brine shrimp cytotoxic potential of crude methanolic extract of Herb Ocimum basilicum (Lamiacea) I Khan, K Ahmad, AT Khalil, J Khan, YA Khan, MS Saqib, MN Umar, ... Journal of Traditional Chinese Medicine 35 (3), 316-322 , 2015 2015 Citations: 55