Glaecir Roseni Mundstock Dias

@ufrj.br

Assistant Professor/ Instituto de Biofísica Carlos Chagas Filho/ Centro de Pesquisa em Medicina de Precisão
Universidade Federal do Rio de Janeiro

Glaecir Roseni Mundstock Dias


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https://researchid.co/glaecirdias

RESEARCH, TEACHING, or OTHER INTERESTS

Physiology (medical), Endocrinology, Toxicology, Multidisciplinary
21

Scopus Publications

928

Scholar Citations

16

Scholar h-index

19

Scholar i10-index

Scopus Publications

  • Intergenerational and transgenerational effects of endocrine-disrupting chemicals in the offspring brain development and behavior
    Glaecir Roseni Mundstock Dias, Fabiana Cardoso Vilela Giusti, Cíntia Onofra de Novais, Maria Aparecida Lima de Oliveira, Alexandre Giusti Paiva, Bruna Kalil-Cutti, Megan M. Mahoney, Jones Bernardes Graceli
    Frontiers in Endocrinology, 2025
    Endocrine-disrupting chemicals (EDCs) are a group of substances that can alter normal body functioning by disrupting the various patterns of hormone secretion and action. Some of these substances are used as plasticizers (e.g., bisphenols and phthalates) and agrochemicals (e.g., vinclozolin). EDC exposure can occur by many routes, including oral by contaminated food and water, through the skin, inhalation, and by placental transfer from mother to fetus or mother to infant (via lactation). The increase in EDCs used by the industry has strongly impacted our health. An increasing number of scientific works have reported the effects of EDCs on cancer development, metabolism, heart disease, and fertility. Most recently, studies on EDCs effects on behavior and the developing brain are raising major concerns related to the formation of sex differences and to the increased prevalence of neuropsychiatric disorders. In this review, we highlight the recent findings of the effects of pre-, peri-, and postnatal exposure to the three well-studied EDCs (i.e., bisphenols (BPA, BPS, BPF, and BPAF), phthalates (DBP, BBP, DEHP, and DiPeP), and vinclozolin (VIN)) on developing brain and behavior across generations in experimental animals.
  • Effects of tributyltin on placental and abnormalities in offspring
    Charles S. da Costa, Hanin Alahmadi, Genoa R. Warner, Maria Tereza Nunes, Glaecir Roseni Mundstock Dias, Leandro Miranda-Alves, Jones B. Graceli
    Archives of Endocrinology and Metabolism, 2024
    Tributyltin (TBT) is an organotin compound and a common persistent environmental pollutant with endocrine-disrupting chemical (EDC) actions. It can accumulate in the environment at various concentrations throughout the food chain in the ecosystem, posing a risk to human health, especially during critical periods such as gestation and fetal and offspring development. In this review, we report the results of studies describing the consequences of TBT exposure on placental and reproductive parameters in offspring of both sexes. Results from in [...]
  • Subacute and low-dose tributyltin exposure disturbs the mammalian hypothalamus-pituitary-thyroid axis in a sex-dependent manner
    Paula Rodrigues-Pereira, Marcelle Novaes Andrade, Ana Paula Santos-Silva, Mariana Pires Teixeira, Paula Soares, Jones Bernardes Graceli, Denise Pires de Carvalho, Glaecir Roseni Mundstock Dias, Andrea Claudia Freitas Ferreira, Leandro Miranda-Alves
    Comparative Biochemistry and Physiology Part C Toxicology and Pharmacology, 2022
  • Subacute exposure to lead promotes disruption in the thyroid gland function in male and female rats
    Niedson Correia de Lima Junior, Juliana Franco Camilo, Pâmella Rodrigues do Carmo, Marcelle Novaes de Andrade, Bernardo Ferreira Braz, Ricardo Erthal Santelli, Lycia de Brito Gitirana, Andrea Claudia Freitas Ferreira, Denise Pires de Carvalho, Leandro Miranda-Alves, Glaecir Roseni Mundstock Dias
    Environmental Pollution, 2021
  • The environmental contaminant tributyltin leads to abnormalities in different levels of the hypothalamus-pituitary-thyroid axis in female rats
    Marcelle Novaes Andrade, Ana Paula Santos-Silva, Paula Rodrigues-Pereira, Francisca Diana Paiva-Melo, Niedson Correa de Lima Junior, Mariana Pires Teixeira, Paula Soares, Glaecir Roseni Munstock Dias, Jones Bernardes Graceli, Denise Pires de Carvalho, Andrea Claudia Freitas Ferreira, Leandro Miranda-Alves
    Environmental Pollution, 2018
  • Multiple mechanistic action of Rosmarinus officinalis L. extract against ethanol effects in an acute model of intestinal damage
    Guilherme Pires Amaral, Fernando Dobrachinski, Nelson Rodrigues de Carvalho, Rômulo Pillon Barcelos, Michele Hinerasky da Silva, Thiago Henrique Lugokenski, Glaecir Roseni Mundstock Dias, Rafael de Lima Portella, Roselei Fachinetto, Félix Alexandre Antunes Soares
    Biomedicine and Pharmacotherapy, 2018
  • Frontiers in endocrine disruption: Impacts of organotin on the hypothalamus-pituitary-thyroid axis
    Ana Paula Santos-Silva, Marcelle Novaes Andrade, Paula Pereira-Rodrigues, Francisca Diana Paiva-Melo, Paula Soares, Jones Bernardes Graceli, Glaecir Roseni Mundstock Dias, Andrea Claudia Freitas Ferreira, Denise Pires de Carvalho, Leandro Miranda-Alves
    Molecular and Cellular Endocrinology, 2018
  • Hypothyroidism Enhanced Ectonucleotidases and Acetylcholinesterase Activities in Rat Synaptosomes can be Prevented by the Naturally Occurring Polyphenol Quercetin
    Jucimara Baldissarelli, Adriana Santi, Roberta Schmatz, Fátima Husein Abdalla, Andréia Machado Cardoso, Caroline Curry Martins, Glaecir R. Mundstock Dias, Nicéia Spanholi Calgaroto, Luana Paula Pelinson, Karine Paula Reichert, Vania Lucia Loro, Vera Maria Melchiors Morsch, Maria Rosa Chitolina Schetinger
    Cellular and Molecular Neurobiology, 2017
  • MCT8 is Downregulated by Short Time Iodine Overload in the Thyroid Gland of Rats
    E. de Souza, G. Dias, R. Cardoso, L. Lima, R. Fortunato, T. Visser, M. Vaisman, A. Ferreira, D. Carvalho
    Hormone and Metabolic Research, 2015
    Wolff-Chaikoff effect is characterized by the blockade of thyroid hormone synthesis and secretion due to iodine overload. However, the regulation of monocarboxylate transporter 8 during Wolff-Chaikoff effect and its possible role in the rapid reduction of T4 secretion by the thyroid gland remains unclear. Patients with monocarboxylate transporter 8 gene loss-of-function mutations and monocarboxylate transporter 8 knockout mice were shown to have decreased serum T4 levels, indicating that monocarboxylate transporter 8 could be involved in the secretion of thyroid hormones from the thyroid gland. Herein, we aimed to evaluate the regulation of monocarboxylate transporter 8 during the Wolff-Chaikoff effect and the escape from iodine overload, besides the importance of iodine organification for this regulation. Monocarboxylate transporter 8 mRNA and protein levels significantly decreased after 1 day of NaI administration to rats, together with decreased serum T4; while no alteration was observed in LAT2 expression. Moreover, both monocarboxylate transporter 8 expression and serum T4 was restored after 6 days of NaI. The inhibition of thyroperoxidase activity by methimazole prevented the inhibitory effect of NaI on thyroid monocarboxylate transporter 8 expression, suggesting that an active thyroperoxidase is necessary for MCT8 downregulation by iodine overload, similarly to other thyroid markers, such as sodium iodide symporter. Therefore, we conclude that thyroid monocarboxylate transporter 8 expression is downregulated during iodine overload and that the normalization of its expression parallels the escape phenomenon. These data suggest a possible role for monocarboxylate transporter 8 in the changes of thyroid hormones secretion during the Wolff-Chaikoff effect and escape.
  • Diphenyl diselenide modulates gene expression of antioxidant enzymes in the cerebral cortex, hippocampus and striatum of female hypothyroid rats
    Glaecir Roseni Mundstock Dias, Ronaldo Medeiros Golombieski, Rafael de Lima Portella, Guilherme Pires do Amaral, Félix Antunes Soares, João Batista Teixeira da Rocha, Cristina Wayne Nogueira, Nilda Vargas Barbosa
    Neuroendocrinology, 2014
    <b><i>Introduction:</i></b> Cellular antioxidant signaling can be altered either by thyroid disturbances or by selenium status. <b><i>Aims:</i></b> To investigate whether or not dietary diphenyl diselenide can modify the expression of genes of antioxidant enzymes and endpoint markers of oxidative stress under hypothyroid conditions. <b><i>Methods:</i></b> Female rats were rendered hypothyroid by continuous exposure to methimazole (MTZ; 20 mg/100 ml in the drinking water) for 3 months. Concomitantly, MTZ-treated rats were either fed or not with a diet containing diphenyl diselenide (5 ppm). mRNA levels of antioxidant enzymes and antioxidant/oxidant status were determined in the cerebral cortex, hippocampus and striatum. <b><i>Results:</i></b> Hypothyroidism caused a marked upregulation in mRNA expression of catalase, superoxide dismutase (SOD-1, SOD-3), glutathione peroxidase (GPx-1, GPx-4) and thioredoxin reductase (TrxR-1) in brain structures. SOD-2 was increased in the cortex and striatum, while TrxR-2 increased in the cerebral cortex. The increase in mRNA expression of antioxidant enzymes was positively correlated with the Nrf-2 transcription in the cortex and hippocampus. Hypothyroidism caused oxidative stress, namely an increase in lipid peroxidation and reactive oxygen species levels in the hippocampus and striatum, and a decrease in nonprotein thiols in the cerebral cortex. Diphenyl diselenide was effective in reducing brain oxidative stress and normalizing most of the changes observed in gene expression of antioxidant enzymes. <b><i>Conclusion:</i></b> The present work corroborates and extends that hypothyroidism disrupts antioxidant enzyme gene expression and causes oxidative stress in the brain. Furthermore, diphenyl diselenide may be considered a promising molecule to counteract these effects in a hypothyroidism state.
  • Effects of quercetin on oxidative stress biomarkers in methimazole - induced hypothyroid rats
    A. Santi, J. Baldissareli, C. Murussi, G. Dias, C. de Menezes, D. Zanini, F. Abdalla, G. Thomé, C. Martins, M. Schetinger, V. Loro
    Experimental and Clinical Endocrinology Diabetes Official Journal German Society of Endocrinology and German Diabetes Association, 2014
  • Neuroprotective Effect of Diphenyl Diselenide in a Experimental Stroke Model: Maintenance of Redox System in Mitochondria of Brain Regions
    Fernando Dobrachinski, Michele Hinerasky da Silva, Cíntia Letícia Cardias Tassi, Nélson Rodrigues de Carvalho, Glaecir Roseni Mundstock Dias, Ronaldo Medeiros Golombieski, Élgion Lúcio da Silva Loreto, João Batista Teixeira da Rocha, Michele Rechia Fighera, Félix Alexandre Antunes Soares
    Neurotoxicity Research, 2014
  • Evaluation of the effects induced by dietary diphenyl diselenide on common carp Cyprinus carpio
    Charlene Menezes, Jossiele Leitemperger, Adriana Santi, Glaecir Dias, Fábio Araújo Pedron, João Radünz Neto, Syed Mahammad Salman, Nilda Berenice Vargas Barbosa, Vania Lucia Loro
    Fish Physiology and Biochemistry, 2014
  • Diphenyl diselenide supplemented diet reduces depressive-like behavior in hypothyroid female rats
    Glaecir Roseni Mundstock Dias, Tielle Moraes de Almeida, Jéssie Haigert Sudati, Fernando Dobrachinski, Sandra Pavin, Félix Alexandre Antunes Soares, Cristina Wayne Nogueira, Nilda Berenice Vargas Barbosa
    Physiology and Behavior, 2014
  • Protective action of ethanolic extract of Rosmarinus officinalis L. in gastric ulcer prevention induced by ethanol in rats
    Guilherme Pires Amaral, Nelson Rodrigues de Carvalho, Rômulo Pillon Barcelos, Fernando Dobrachinski, Rafael de Lima Portella, Michele Hinerasky da Silva, Thiago Henrique Lugokenski, Glaecir Roseni Mundstock Dias, Sônia Cristina Almeida da Luz, Aline Augusti Boligon, Margareth Linde Athayde, Marcos Antonio Villetti, Félix Alexandre Antunes Soares, Roselei Fachinetto
    Food and Chemical Toxicology, 2013
  • Valeriana officinalis attenuates the rotenone-induced toxicity in drosophila melanogaster
    Jéssie Haigert Sudati, Francielli Araújo Vieira, Sandra Sartoretto Pavin, Glaecir Roseni Mundstock Dias, Rodrigo Lopes Seeger, Ronaldo Golombieski, Margareth Linde Athayde, Félix Antunes Soares, João Batista Teixeira Rocha, Nilda Vargas Barbosa
    Neurotoxicology, 2013
  • Behavior and brain enzymatic changes after long-term intoxication with cadmium salt or contaminated potatoes
    Jamile F. Gonçalves, Fernando T. Nicoloso, Pauline da Costa, Júlia G. Farias, Fabiano B. Carvalho, Michelle M. da Rosa, Jessié M. Gutierres, Fátima H. Abdalla, Juliana S.F. Pereira, Glaecir R.M. Dias, Nilda B.V. Barbosa, Valderi L. Dressler, Maribel A. Rubin, Vera M. Morsch, Maria Rosa C. Schetinger
    Food and Chemical Toxicology, 2012
  • Diphenyl diselenide diet intake improves spatial learning and memory deficits in hypothyroid female rats
    Glaecir Roseni Mundstock Dias, Francielli Araújo Vieira, Fernando Dobrachinski, Jéssika Cristina Bridi, Rodrigo de Souza Balk, Félix Antunes Soares, Cristina Wayne Nogueira, Nilda Berenice de Vargas Barbosa
    International Journal of Developmental Neuroscience, 2012
  • Effect of repeated restraint stress and clomipramine on Na+/K+-ATPase activity and behavior in rats
    Rodrigo de Souza Balk, Michele Hinerasky da Silva, Jessika Cristina Bridi, Nelson Rodrigues Carvalho, Rafael de Lima Portella, Fernando Dobrachinski, Guilherme Pires Amaral, Rômulo Barcelos, Glaecir Roseni Mundstock Dias, João Batista Teixeira da Rocha, Nilda Berenice Vargas Barbosa, Felix Alexandre Antunes Soares
    International Journal of Developmental Neuroscience, 2011
  • Clomipramine treatment and repeated restraint stress alter parameters of oxidative stress in brain regions of male rats
    Rodrigo de Souza Balk, Jessika Cristina Bridi, Rafael de Lima Portella, Nelson Rodrigues Carvalho, Fernando Dobrachinski, Michele Hinerasky da Silva, Guilherme Pires Amaral, Glaecir Roseni Mundstock Dias, Nilda de Vargas Barbosa, Felix Alexandre Antunes Soares
    Neurochemical Research, 2010
  • Hormetic acute response and chronic effect of ethanol on adenine nucleotide hydrolysis in rat platelets
    Glaecir R. Mundstock Dias, Maria Rosa Chitolina Schetinger, Roselia Spanevello, Cinthia Melazzo Mazzanti, Roberta Schmatz, Vânia Lúcia Loro, Vera Maria Morsch
    Archives of Toxicology, 2009

RECENT SCHOLAR PUBLICATIONS

  • Endocrine-disrupting properties of heavy metal exposure contribute to the intergenerational effects on learning and memory
    GRM Dias, HD Zomer, NF Silva, JB Graceli
    Frontiers in Endocrinology 17, 1761556 , 2026
    2026
    Citations: 1
  • Oxidative Stress Parameters are Differentially Regulated in Visceral and Subcutaneous Adipose Tissue by Western Diet and Intermittent Fasting
    NCL Junior, T Fernandes, L Serra, AL Dias, L Matta, FHC Medeiros, ...
    Hormone and Metabolic Research 57, 396-404 , 2025
    2025
    Citations: 1
  • Intergenerational and transgenerational effects of endocrine-disrupting chemicals in the offspring brain development and behavior
    GRM Dias, FCV Giusti, CO de Novais, MAL de Oliveira, AG Paiva, ...
    Frontiers in endocrinology 16, 1571689 , 2025
    2025
    Citations: 14
  • Endocrine Disruptors Chemicals: Impacts of Bisphenol A, Tributyltin and Lead on Thyroid Function
    GRM Dias, ACF Ferreira, L Miranda-Alves, JB Graceli, DP Carvalho
    Molecular and Cellular Endocrinology , 2025
    2025
    Citations: 13
  • SEQUÊNCIA DIDÁTICA INVESTIGATIVA SOBRE O DIABETES MELLITUS NA INTEGRAÇÃO DO CONHECIMENTO DO SISTEMA ENDÓCRINO
    APR da Costa Felix
    INSTITUTO DE BIOLOGIA , 2025
    2025
  • Effects of tributyltin on placental and reproductive abnormalities in offspring
    CS da Costa, H Alahmad, GR Warner, MT Nunes, GRM Dias, ...
    Archives of Endocrinology and Metabolism 68, e240186 , 2024
    2024
    Citations: 2
  • APRENDIZAGEM BASEADA EM EQUIPES (TEAM-BASED LEARNING) PARA ALUNOS DAS SÉRIES FINAIS DO ENSINO FUNDAMENTAL
    T Vieira da Silva, GRM Dias, KLA Souza
    Revista de Ensino de Biologia da SBEnBio 17, 740-764 , 2024
    2024
    Citations: 5
  • Subacute and low-dose tributyltin exposure disturbs the mammalian hypothalamus-pituitary-thyroid axis in a sex-dependent manner
    P Rodrigues-Pereira, MN Andrade, AP Santos-Silva, MP Teixeira, ...
    Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology … , 2022
    2022
    Citations: 22
  • A experiência de uma escola da Rede Estadual de Ensino do Rio de Janeiro: Roteiro de implantação de um Clube de Ciências como ferramenta de educação científica
    LA Teixeira, GRM Dias
    Revista de Ensino de Biologia da SBEnBio 14 (2), 727-747 , 2021
    2021
  • Subacute exposure to lead promotes disruption in the thyroid gland function in male and female rats
    NC de Lima Junior, JF Camilo, PR do Carmo, MN de Andrade, BF Braz, ...
    Environmental Pollution 274, 115889 , 2021
    2021
    Citations: 9
  • Desenvolvimento de revistas didáticas como estratégia lúdica para o ensino da Morfofisiologia do sistema endócrino
    JL Silva
    Universidade Federal do Rio de Janeiro , 2019
    2019
    Citations: 4
  • The content analysis of Human Physiology questions in the Examination of Natural Sciences and their Technologies in the Exame Nacional do Ensino Médio (1998-2016)
    LAS Miranda, ACF Ferreira, GRM Dias
    Ciência & Educação 25 (2), 375-393 , 2019
    2019
  • Análise de conteúdo das questões de Fisiologia Humana da Prova de Ciências da Natureza e suas Tecnologias do Exame Nacional do Ensino Médio (1998-2016)
    LAS Miranda, ACF Ferreira, GRM Dias
    Ciência & Educação 25 (2), 375-393 , 2019
    2019
    Citations: 6
  • The environmental contaminant tributyltin leads to abnormalities in different levels of the hypothalamus-pituitary-thyroid axis in female rats
    MN Andrade, AP Santos-Silva, P Rodrigues-Pereira, FD Paiva-Melo, ...
    Environmental Pollution 241, 636-645 , 2018
    2018
    Citations: 33
  • Multiple mechanistic action of Rosmarinus officinalis L. extract against ethanol effects in an acute model of intestinal damage
    GP Amaral, F Dobrachinski, NR de Carvalho, RP Barcelos, MH da Silva, ...
    Biomedicine & Pharmacotherapy 98, 454-459 , 2018
    2018
    Citations: 16
  • Frontiers in endocrine disruption: Impacts of organotin on the hypothalamus-pituitary-thyroid axis
    AP Santos-Silva, MN Andrade, P Pereira-Rodrigues, FD Paiva-Melo, ...
    Molecular and cellular endocrinology 460, 246-257 , 2018
    2018
    Citations: 77
  • Hypothyroidism enhanced ectonucleotidases and acetylcholinesterase activities in rat synaptosomes can be prevented by the naturally occurring polyphenol quercetin
    J Baldissarelli, A Santi, R Schmatz, FH Abdalla, AM Cardoso, CC Martins, ...
    Cellular and molecular neurobiology 37 (1), 53-63 , 2017
    2017
    Citations: 23
  • MCT8 is downregulated by short time iodine overload in the thyroid gland of rats
    ECL De Souza, GRM Dias, RC Cardoso, LP Lima, RS Fortunato, ...
    Hormone and Metabolic Research 47 (12), 910-915 , 2015
    2015
    Citations: 27
  • Neuroprotective effect of diphenyl diselenide in a experimental stroke model: maintenance of redox system in mitochondria of brain regions
    F Dobrachinski, MH da Silva, CLC Tassi, NR de Carvalho, GRM Dias, ...
    Neurotoxicity research 26 (4), 317-330 , 2014
    2014
    Citations: 39
  • Effects of quercetin on oxidative stress biomarkers in methimazole–induced hypothyroid rats
    A Santi, J Baldissareli, CR Murussi, GRM Dias, CC de Menezes, D Zanini, ...
    Experimental and Clinical Endocrinology & Diabetes 122 (09), 533-539 , 2014
    2014
    Citations: 23

MOST CITED SCHOLAR PUBLICATIONS

  • Protective action of ethanolic extract of Rosmarinus officinalis L. in gastric ulcer prevention induced by ethanol in rats
    GP Amaral, NR de Carvalho, RP Barcelos, F Dobrachinski, ...
    Food and chemical toxicology 55, 48-55 , 2013
    2013
    Citations: 218
  • Valeriana officinalis attenuates the rotenone-induced toxicity in Drosophila melanogaster
    JH Sudati, FA Vieira, SS Pavin, GRM Dias, RL Seeger, R Golombieski, ...
    Neurotoxicology 37, 118-126 , 2013
    2013
    Citations: 141
  • Behavior and brain enzymatic changes after long-term intoxication with cadmium salt or contaminated potatoes
    JF Gonçalves, FT Nicoloso, P da Costa, JG Farias, FB Carvalho, ...
    Food and Chemical Toxicology 50 (10), 3709-3718 , 2012
    2012
    Citations: 101
  • Frontiers in endocrine disruption: Impacts of organotin on the hypothalamus-pituitary-thyroid axis
    AP Santos-Silva, MN Andrade, P Pereira-Rodrigues, FD Paiva-Melo, ...
    Molecular and cellular endocrinology 460, 246-257 , 2018
    2018
    Citations: 77
  • Neuroprotective effect of diphenyl diselenide in a experimental stroke model: maintenance of redox system in mitochondria of brain regions
    F Dobrachinski, MH da Silva, CLC Tassi, NR de Carvalho, GRM Dias, ...
    Neurotoxicity research 26 (4), 317-330 , 2014
    2014
    Citations: 39
  • Diphenyl diselenide diet intake improves spatial learning and memory deficits in hypothyroid female rats
    GRM Dias, FA Vieira, F Dobrachinski, JC Bridi, R de Souza Balk, ...
    International Journal of Developmental Neuroscience 30 (2), 83-89 , 2012
    2012
    Citations: 36
  • The environmental contaminant tributyltin leads to abnormalities in different levels of the hypothalamus-pituitary-thyroid axis in female rats
    MN Andrade, AP Santos-Silva, P Rodrigues-Pereira, FD Paiva-Melo, ...
    Environmental Pollution 241, 636-645 , 2018
    2018
    Citations: 33
  • Diphenyl diselenide supplemented diet reduces depressive-like behavior in hypothyroid female rats
    GRM Dias, TM de Almeida, JH Sudati, F Dobrachinski, S Pavin, ...
    Physiology & behavior 124, 116-122 , 2014
    2014
    Citations: 32
  • Clomipramine treatment and repeated restraint stress alter parameters of oxidative stress in brain regions of male rats
    R de Souza Balk, JC Bridi, R de Lima Portella, NR Carvalho, ...
    Neurochemical research 35 (11), 1761-1770 , 2010
    2010
    Citations: 31
  • MCT8 is downregulated by short time iodine overload in the thyroid gland of rats
    ECL De Souza, GRM Dias, RC Cardoso, LP Lima, RS Fortunato, ...
    Hormone and Metabolic Research 47 (12), 910-915 , 2015
    2015
    Citations: 27
  • Hypothyroidism enhanced ectonucleotidases and acetylcholinesterase activities in rat synaptosomes can be prevented by the naturally occurring polyphenol quercetin
    J Baldissarelli, A Santi, R Schmatz, FH Abdalla, AM Cardoso, CC Martins, ...
    Cellular and molecular neurobiology 37 (1), 53-63 , 2017
    2017
    Citations: 23
  • Effects of quercetin on oxidative stress biomarkers in methimazole–induced hypothyroid rats
    A Santi, J Baldissareli, CR Murussi, GRM Dias, CC de Menezes, D Zanini, ...
    Experimental and Clinical Endocrinology & Diabetes 122 (09), 533-539 , 2014
    2014
    Citations: 23
  • Subacute and low-dose tributyltin exposure disturbs the mammalian hypothalamus-pituitary-thyroid axis in a sex-dependent manner
    P Rodrigues-Pereira, MN Andrade, AP Santos-Silva, MP Teixeira, ...
    Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology … , 2022
    2022
    Citations: 22
  • Diphenyl diselenide modulates gene expression of antioxidant enzymes in the cerebral cortex, hippocampus and striatum of female hypothyroid rats
    G Roseni Mundstock Dias, R Medeiros Golombieski, R de Lima Portella, ...
    Neuroendocrinology 100 (1), 45-59 , 2014
    2014
    Citations: 19
  • Multiple mechanistic action of Rosmarinus officinalis L. extract against ethanol effects in an acute model of intestinal damage
    GP Amaral, F Dobrachinski, NR de Carvalho, RP Barcelos, MH da Silva, ...
    Biomedicine & Pharmacotherapy 98, 454-459 , 2018
    2018
    Citations: 16
  • Evaluation of the effects induced by dietary diphenyl diselenide on common carp Cyprinus carpio
    C Menezes, J Leitemperger, A Santi, G Dias, FA Pedron, JR Neto, ...
    Fish physiology and biochemistry 40 (1), 141-149 , 2014
    2014
    Citations: 16
  • Intergenerational and transgenerational effects of endocrine-disrupting chemicals in the offspring brain development and behavior
    GRM Dias, FCV Giusti, CO de Novais, MAL de Oliveira, AG Paiva, ...
    Frontiers in endocrinology 16, 1571689 , 2025
    2025
    Citations: 14
  • Effect of repeated restraint stress and clomipramine on Na+/K+-ATPase activity and behavior in rats
    R de Souza Balk, MH da Silva, JC Bridi, NR Carvalho, R de Lima Portella, ...
    International Journal of Developmental Neuroscience 29 (8), 909-916 , 2011
    2011
    Citations: 14
  • Endocrine Disruptors Chemicals: Impacts of Bisphenol A, Tributyltin and Lead on Thyroid Function
    GRM Dias, ACF Ferreira, L Miranda-Alves, JB Graceli, DP Carvalho
    Molecular and Cellular Endocrinology , 2025
    2025
    Citations: 13
  • Subacute exposure to lead promotes disruption in the thyroid gland function in male and female rats
    NC de Lima Junior, JF Camilo, PR do Carmo, MN de Andrade, BF Braz, ...
    Environmental Pollution 274, 115889 , 2021
    2021
    Citations: 9