Giovanna Casili
@unime.it
University of Messina
Scopus Publications
- Nrf2/NOX2 Pathway Dysregulation and Oxidative Stress Biomarkers in Gaucher Disease–Associated Parkinsonism: Insights Into a Potential Therapeutic Target
Alessio Ardizzone, Marika Lanza, Anna Paola Capra, Giovanna Casili, Maria Bulzomì, Fabiola De Luca, Irene Paterniti, Michela Campolo, Emanuela Esposito
Journal of Cellular and Molecular Medicine, 2026
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder, yet its underlying genetic and molecular mechanisms remain incompletely understood. Variants in the GBA gene, encoding the lysosomal enzyme glucocerebrosidase, are not only responsible for Gaucher disease (GD) but also represent a significant genetic risk factor for PD, contributing to lysosomal dysfunction, oxidative stress and autophagy impairment. Among the key regulators of redox homeostasis, the Nrf2/NOX2 signalling axis has emerged as a pivotal pathway in the modulation of neuroinflammation and neurodegeneration. This study aims to explore the pathogenic link between GBA mutations and PD, focusing on the redox imbalance and the role of Nrf2 signalling in an in vivo Gba D409V knock‐in (KI) mouse model, compared to wild‐type (WT) C57BL/6J controls. Animals 8‐weeks old were evaluated over a 3‐month period, with tissue and behavioural assessments conducted at 7, 14, 30, 60 and 90 days. Early timepoints (7 and 14 days) did not reveal significant changes in behavioural performance, expression of PD‐related markers (TH, DAT, α‐synuclein), or oxidative stress indicators, including Nrf2, NOX2, malondialdehyde (MDA) and nitrate/nitrite levels. However, at 30, 60 and especially 90 days, significant alterations emerged, particularly a disrupted Nrf2/NOX2 balance, accompanied by molecular and biochemical signatures of oxidative stress. These findings suggest a time‐dependent progression of oxidative alterations in this GD model and support the role of GBA variants in promoting neurodegenerative processes. Unravelling these mechanisms is essential for the identification of early biomarkers and may offer new therapeutic insights for GBA1 ‐associated PD. - RETRACTED: Efficacy of a Product Containing Xyloglucan and Pea Protein on Intestinal Barrier Function in a Partial Restraint Stress Animal Model (International Journal of Molecular Sciences, (2022), 23, 4, (2269), 10.3390/ijms23042269)
Sarah Adriana Scuderi, Giovanna Casili, Marika Lanza, Alessio Ardizzone, Luca Pantaleo, Michela Campolo, Irene Paterniti, Laura Cucinotta, Salvatore Cuzzocrea, Emanuela Esposito
International Journal of Molecular Sciences, 2026
The journal retracts the article titled “Efficacy of a Product Containing Xyloglucan and Pea Protein on Intestinal Barrier Function in a Partial Restraint Stress Animal Model” [...] - Molecular insights into NLRP3 inflammasome and miRNA modulation in oral cancer
Deborah Mannino, Morena D’Ariano, Ivana Bello, Irene Paterniti, Giovanna Casili, Elisabetta Panza
Frontiers in Pharmacology, 2026
The NLRP3 inflammasome, a cytosolic multiprotein complex composed of NLRP3, ASC, and caspase-1, orchestrates the maturation of interleukin-1β (IL-1β) and interleukin-18 (IL-18) and the induction of pyroptosis, acting as a central mediator of innate immunity. Although physiologically protective, aberrant NLRP3 activation has been increasingly implicated in tumorigenesis. In oral squamous cell carcinoma (OSCC), current evidence points to a predominantly pro-tumorigenic role, with elevated NLRP3 expression correlating with tumor progression, lymph node metastasis, advanced pathological stage, and reduced survival. Functional studies demonstrate that genetic silencing or pharmacological inhibition of NLRP3 enhances apoptosis and reduces tumor burden. An additional regulatory layer is provided by microRNAs (miRNAs), which fine-tune NLRP3 expression at the post-transcriptional level. Since the identification of miR-223-3p as the first miRNA to directly target NLRP3, several miRNAs, including miR-22-3p, miR-7-5p, and miR-30e-5p, have been shown to suppress NLRP3 activity in various pathological settings, including oral squamous cell carcinoma, where miR-22-3p downregulates NLRP3, inhibiting its proliferation, migration, and invasion. Therefore, the NLRP3 inflammasome represents a key player in cancer development, and its regulation by miRNAs highlights its importance and clinical potential. This review summarizes mechanistic and clinical knowledge on the biology of NLRP3, highlights its dual role in cancer hallmarks, and discusses the therapeutic promise of targeting the NLRP3-miRNA axis in the management of oral cancer. - Aesculus hippocastanum Extract Exerts Neuroprotective Effects in an MPP+-Induced Parkinson's Disease Model via PPARγ Activation
Sarah Adriana Scuderi, Alessio Ardizzone, Giovanna Casili, Deborah Mannino, Antonio Catalfamo, Marika Lanza, Emanuela Esposito
Journal of Cellular and Molecular Medicine, 2026
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterised by the loss of dopaminergic neurons in the substantia nigra. In this study, we investigated the neuroprotective and anti‐inflammatory potential of Aesculus hippocastanum (horse chestnut extract, HCE) in an in vitro model of PD. Human neuroblastoma SH‐SY5Y cells were treated with the neurotoxin 1‐methyl‐4‐phenylpyridinium (MPP + ) (1 mM) and/or in combination with HCE at the concentrations of 15.6, 31.2 and 62.5 μg/mL for 24 h. After 24 h, several analyses have been performed. Treatment with HCE at the concentrations of 31.2 and 62.5 μg/mL significantly improved cell viability following MPP + ‐induced neurotoxicity. Furthermore, HCE effectively modulated key Parkinsonian markers by restoring tyrosine hydroxylase (TH) and reducing the number of α‐syn‐positive cells. At the same concentrations, HCE also attenuated NF‐κB signalling pathway activation and diminished the release of pro‐inflammatory cytokines IL‐1β, IL‐17, and TNF‐α. Notably, HCE promoted the activation of the nuclear receptor peroxisome proliferator activated receptor gamma (PPARγ), known for its neuroprotective properties, and reduced both oxidative and nitrosative stress. Crucially, silencing of PPARγ abolished the beneficial effects of HCE, indicating that its neuroprotective actions are mediated specifically through PPARγ activation. Thus, these findings suggest that HCE confers neuroprotection in vitro by regulating inflammation and oxidative stress primarily via PPARγ modulation. - Aberrant Cell Cycle Gene Expression in a Transgenic Mouse Model of Alzheimer’s Disease
Marika Lanza, Michele Scuruchi, Alessandra Saitta, Rossella Basilotta, Federica Aliquò, Giovanna Casili, Emanuela Esposito, Agata Copani, Salvatore Oddo, Antonella Caccamo
Cells, 2026
Alzheimer’s disease (AD) is increasingly recognized as a disorder that extends beyond amyloid-β (Aβ) and tau pathology. To this end, growing evidence suggests that aberrant neuronal cell cycle re-entry (CCR) may contribute to neurodegeneration. To investigate this mechanism, we profiled the expression of 84 cell cycle-related genes in the brains of aged APP/PS1 mice, a widely used transgenic model of AD, and compared them with age-matched non-transgenic littermates. Our analysis revealed 32 differentially expressed genes (DEGs), 8 of which exhibited significant changes (fold change > 2, p < 0.05). Several of these DEGs, including CDC7 and CCNC, displayed consistent dysregulation in human AD brains as assessed using the AMP-AD knowledge portal, supporting their translational relevance. Furthermore, integration with miRNA prediction analyses identified candidate post-transcriptional regulators of these DEGs, highlighting novel layers of regulation. Collectively, our results provide the first systematic overview of cell cycle gene dysregulation in aged APP/PS1 mice, establish cross-species concordance with human AD, and propose miRNA–gene interactions as potential contributors to neuronal vulnerability. These findings underscore the importance of cell cycle pathways in AD pathogenesis and point to new avenues for therapeutic exploration. - Neurotransmitter-Mediated Signaling in Glioblastoma and Glial Tumors: Biology and Therapeutic Opportunities
Pietro Tralongo, Mariagiovanna Ballato, Valeria Zuccalà, Vincenzo Fiorentino, Walter Giordano, Giovanna Casili, Fabiola Bellinghieri, Gerardo Caruso, Filippo Flavio Angileri, Guido Fadda, Maurizio Martini, Maria Caffo
Oncology Research, 2026
Glioblastoma (GB) is the most common primary malignant brain tumor of adulthood, and despite optimal safe resection and chemoradiation, it is still lethal. Neuroscience of cancer has shown that neuronal activities, as well as neurotransmitters, play an active role in the glioma microenvironment. This article aims to integrate the existing literature on the role of neurotransmitters and their receptors in glioblastoma, as well as other gliomas, highlighting areas of therapeutic intervention in the neuron-tumor interface. We will describe the neuro–glioma interface, including functional neuron–glioma synapses and activity-dependent tumor growth. We will also discuss major neurotransmitter systems involved in glioma pathobiology: glutamate, gamma aminobutyric acid, acetylcholine, dopamine, serotonin, norepinephrine, and other neurotransmitters. We will highlight that these neurotransmitter systems activate common intracellular signaling pathways that control tumor proliferation, invasion, metabolic reprogramming, immune suppression, therapy resistance, etc. In addition, some reports have found tumor-suppressing effects depending on the context. The involvement of neurotransmitter-driven signaling pathways represents a promising area of clinical potential in glioma pathobiology. In particular, focusing on key neurotransmitter systems with blood–brain barrier-permeable agents like alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA/Xc−) system, Muscarinic acetylcholine receptor M3 (CHRM3), dopamine receptor D2, monoamine oxidase A, etc., may enhance drug-repurposing research as well as development of novel anti–neuron–glioma agents. - Troxerutin Potentiated Temozolomide Induced Antitumor Effect in 2D and 3D Glioblastoma Models
Deborah Mannino, Elsa Calcaterra, Sarah Adriana Scuderi, Maria Caffo, Fabiola De Luca, Antonio Catalfamo, Giovanna Casili, Irene Paterniti
Journal of Cellular and Molecular Medicine, 2025
Glioblastoma (GBM) is a highly aggressive brain tumour characterised by rapid proliferation and high invasiveness. Temozolomide (TMZ) is the first‐line chemotherapy, but its efficacy is often compromised by intrinsic or acquired resistance and significant side effects. Recent studies have demonstrated that combining TMZ with natural compounds can enhance therapeutic efficacy through synergistic mechanisms and reduce systemic toxicity. In this study, the adjuvant potential of troxerutin (TROX), a natural flavonoid present found in tea, coffee, cereals, fruits and vegetables, and known for its antioxidant and anti‐inflammatory properties, was evaluated in an in vitro model of human U87 cells. The TROX–TMZ combination showed a significant synergistic effect, effectively reducing cell viability, clonogenic capacity, migration and epithelial‐mesenchymal transition (EMT), as well as promoting apoptosis. The combined treatment also modulated oxidative stress and inflammation by activating the KEAP1/NRF2 axis, resulting in increased levels of HO‐1, GSH and SOD1, and decreased ROMO1, ROS, nitrites and pro‐inflammatory cytokines (IL‐6, TNF‐α and IL‐1β). These effects were also confirmed in three‐dimensional models (spheroids), suggesting that the combination exerts significant antitumor activity. These results indicate that TROX could represent an effective adjuvant in the treatment of GBM, providing a novel therapeutic strategy to potentiate the antitumor effects of TMZ. - GIT 27 modulates TLR4/Src/NOX2 signaling pathway: A potential therapeutic strategy to decrease neuroinflammation, oxidative stress and neuronal cell death in Parkinson's disease
Alessio Ardizzone, Laura Cucinotta, Giovanna Casili, Marika Lanza, Ahmed Hasan, Michela Campolo, Emanuela Esposito, Irene Paterniti
Free Radical Biology and Medicine, 2025 - A Topical Combination of Xyloglucan and Pea Protein Effectively Manages Oral Ulcers In Vivo
Alessia Filippone, Giovanna Casili, Marika Lanza, Michela Campolo, Irene Paterniti, Laura Cucinotta, Rossella Basilotta, Alessio Ardizzone, Emanuela Esposito
Journal of Oral Pathology and Medicine, 2025
BackgroundAphthous stomatitis (AS) is a common idiopathic condition that affects approximately 5% to 25% of the general population. AS is characterized by recurrent painful aphthous ulcers on non‐keratinized oral mucous membranes. Lifestyle modifications and topical treatments are often used to manage symptoms, but no definitive cure exists. This study aims to evaluate the ability of a topical gel containing xyloglucan and pea protein (TXP), two mucoprotective substances, to restore the integrity of oral epithelial cells and manage inflammation associated with AS.MethodsIn this study, oral ulcers were induced in rats by applying a phenol solution for 60 s to the mucosa of the left cheek. Following the formation of the lesion (24 h later) topical treatment with TXP was carried out for 2, 4, and 5 days. The healing properties of TXP were assessed by histopathological examination of the oral mucosa through the evaluation of morphological criteria such as hyperemia, edema, and presence of neutrophilic infiltration and by measuring the expression levels of inflammatory markers such as TNF‐α and IL‐2.ResultsResults demonstrated that TXP was able to effectively treat oral ulcers by reducing the degree of hyperemia and edema in cheek tissue already at day 4. Moreover, TXP significantly decreased the levels of IL‐2 and TNF‐α after 4 days of gel application.ConclusionsThis study demonstrates that TXP possesses a significant ulcer repairing ability in vivo, as it effectively restores the integrity of oral mucosal tissue, thus helping to reduce inflammation. - PF-04691502, a PI3K/mTOR Dual Inhibitor, Ameliorates AD-like Pathology in a Mouse Model of AD
Marika Lanza, Rossella Basilotta, Antonella Caccamo, Giovanna Casili, Alberto Repici, Salvatore Oddo, Emanuela Esposito
Cells, 2025
Alzheimer’s disease (AD) is a neurodegenerative disorder that significantly impacts the lives of patients and their families. The pathological features of AD include the accumulation of amyloid-β (Aβ) and Tau, which disrupt neuronal function and communication, ultimately leading to neuronal loss and brain atrophy. Efforts to understand the molecular mechanisms underlying these pathological changes have led to advancements in diagnostic techniques and potential therapeutic interventions. However, the complexity of AD necessitates further research to develop more effective treatments and, ideally, preventive measures. Extensive research suggests that diminishing mTOR signaling increases lifespan and health span across various species. Increased PI3K/mTOR signaling has been linked to the progression of AD pathology, leading to neuronal degeneration and impairments in cognitive function. In this study, we explored the therapeutic potential of PF-04691502, a dual PI3K/mTOR inhibitor, in Alzheimer’s disease (AD)-like pathology using male and female B6.Cg-Tg(APPswe, PSEN1dE9)85Dbo/Mmjax mice (APP/PS1), a well-established transgenic model of AD. Eighteen-month-old APP/PS1 and wild-type mice received oral administration of PF-04691502 at a dose of 1 mg/kg for 12 weeks. Following the treatment period, spatial learning and memory were evaluated using the Morris water maze. Subsequently, the mice brains were collected for neuropathological and biochemical assessments. Our findings showed that PF-04691502 enhanced cognitive performance in APP/PS1 mice and significantly reduced insoluble Aβ accumulation in the brain. Mechanistically, these effects were associated with enhanced autophagy induction. Treatment with PF-04691502 increased the LC3-II/LC3-I ratio, upregulated Beclin-1, and elevated LAMP-2 levels, indicative of stimulated autophagosome formation and lysosomal activity. Overall, these preclinical results suggest that PF-04691502 holds promise as a potential therapeutic agent for AD and other aging-related neurodegenerative diseases involving mTOR pathway dysregulation. - The Role of S6K1 in Aging and Alzheimer’s Disease: Mechanistic Insights and Therapeutic Potential
Salvatore Oddo, Marika Lanza, Giovanna Casili, Antonella Caccamo
International Journal of Molecular Sciences, 2025 - PI3K/mTOR Signaling Pathway Dual Inhibition for the Management of Neuroinflammation: Novel Insights from In Vitro Models
Alessio Ardizzone, Sarah Adriana Scuderi, Giovanna Casili, Rossella Basilotta, Emanuela Esposito, Marika Lanza
Biomolecules, 2025 - The Inhibition of Prolyl Endopeptidase (PREP) by KYP-2047 Treatment to Reduce Myocardial Ischemia/Reperfusion Injury
Laura Cucinotta, Nicoletta Palermo, Alessio Ardizzone, Anna Paola Capra, Michela Campolo, Emanuela Esposito, Giovanna Casili, Marika Lanza
Antioxidants, 2025 - KRAS–SOS-1 Inhibition as New Pharmacological Target to Counteract Anaplastic Thyroid Carcinoma (ATC)
Deborah Mannino, Rossella Basilotta, Fabiola De Luca, Giovanna Casili, Emanuela Esposito, Irene Paterniti
International Journal of Molecular Sciences, 2025 - Correction to: Efficacy of a Novel Therapeutic, Based on Natural Ingredients and Probiotics, in a Murine Model of Multiple Food Intolerance and Maldigestion (Nutrients, (2022), 14, 11, (2251), 10.3390/nu14112251)
Alessio Ardizzone, Marika Lanza, Giovanna Casili, Michela Campolo, Irene Paterniti, Salvatore Cuzzocrea, Emanuela Esposito
Nutrients, 2024 - Benzyl isothiocyanate suppresses development of thyroid carcinoma by regulating both autophagy and apoptosis pathway
Rossella Basilotta, Giovanna Casili, Deborah Mannino, Alessia Filippone, Marika Lanza, Anna Paola Capra, Domenico Giosa, Stefano Forte, Lorenzo Colarossi, Dorotea Sciacca, Emanuela Esposito, Irene Paterniti
Iscience, 2024 - The Protective Role of Troxerutin (Trox) in Counteracting Anaplastic Thyroid Carcinoma (ATC) Progression
Valentina Bova, Rossella Basilotta, Giovanna Casili, Marika Lanza, Alessia Filippone, Michela Campolo, Anna Paola Capra, Giulia Vitale, Giulia Chisari, Cristina Colarossi, Dario Giuffrida, Irene Paterniti, Emanuela Esposito
Biomedicines, 2024 - Corrigendum to “Adelmidrol, a palmitoylethanolamide analogue, as a new pharmacological treatment for the management of acute and chronic inflammation” [Biochem. Pharmacol. 119 (2016) 27–41, (S0006295216302611), (10.1016/j.bcp.2016.09.001)]
Daniela Impellizzeri, Rosanna Di Paola, Marika Cordaro, Enrico Gugliandolo, Giovanna Casili, Valeria Maria Morittu, Domenico Britti, Emanuela Esposito, Salvatore Cuzzocrea
Biochemical Pharmacology, 2024 - DKK3 Expression in Glioblastoma: Correlations with Biomolecular Markers
Maria Caffo, Giovanna Casili, Gerardo Caruso, Valeria Barresi, Michela Campolo, Irene Paterniti, Letteria Minutoli, Tamara Ius, Emanuela Esposito
International Journal of Molecular Sciences, 2024 - Efficacy of an oral suspension containing xyloglucan and pea proteins on a murine model of gastroesophageal reflux disease
Alessio Ardizzone, Deborah Mannino, Giovanna Casili, Michela Campolo, Irene Paterniti, et al.
Phytotherapy Research, 2024 - Correction to: Therapeutic Potential of BAY-117082, a Selective NLRP3 Inflammasome Inhibitor, on Metastatic Evolution in Human Oral Squamous Cell Carcinoma (OSCC) (Cancers, (2023), 15, 10, (2796), 10.3390/cancers15102796)
Giovanna Casili, Sarah Adriana Scuderi, Marika Lanza, Alessia Filippone, Deborah Mannino, Raffaella Giuffrida, Cristina Colarossi, Marzia Mare, Anna Paola Capra, Federica De Gaetano, Marco Portelli, Angela Militi, Salvatore Cuzzocrea, Irene Paterniti, Emanuela Esposito
Cancers, 2024 - Prolyl oligopeptidase inhibition ameliorates experimental pulmonary fibrosis both in vivo and in vitro
Laura Cucinotta, Deborah Mannino, Giovanna Casili, Alberto Repici, Lelio Crupi, Irene Paterniti, Emanuela Esposito, Michela Campolo
Respiratory Research, 2023 - Effect of a combination of pea protein, grape seed extract and lactic acid in an in vivo model of bacterial vaginosis
Marika Lanza, Sarah Adriana Scuderi, Anna Paola Capra, Giovanna Casili, Alessia Filippone, Michela Campolo, Salvatore Cuzzocrea, Emanuela Esposito, Irene Paterniti
Scientific Reports, 2023 - Neuroprotective effects of GSK-343 in an in vivo model of MPTP-induced nigrostriatal degeneration
Deborah Mannino, Sarah Adriana Scuderi, Giovanna Casili, Valentina Bova, Laura Cucinotta, Marika Lanza, Alessia Filippone, Emanuela Esposito, Irene Paterniti
Journal of Neuroinflammation, 2023 - bFGF-like Activity Supported Tissue Regeneration, Modulated Neuroinflammation, and Rebalanced Ca2+ Homeostasis following Spinal Cord Injury
Alessio Ardizzone, Valentina Bova, Giovanna Casili, Alessia Filippone, Marika Lanza, Alberto Repici, Emanuela Esposito, Irene Paterniti
International Journal of Molecular Sciences, 2023 - An RNAi-Mediated Reduction in Transcription Factor Nrf-2 Blocks the Positive Effects of Dimethyl Fumarate on Metabolic Stress in Alzheimer’s Disease
Marika Lanza, Rossella Basilotta, Salvatore Cuzzocrea, Maria Bulzomì, Salvatore Oddo, Giovanna Casili, Emanuela Esposito
International Journal of Molecular Sciences, 2023 - Efficacy of the Radical Scavenger, Tempol, to Reduce Inflammation and Oxidative Stress in a Murine Model of Atopic Dermatitis
Alessio Ardizzone, Alberto Repici, Anna Paola Capra, Federica De Gaetano, Valentina Bova, Giovanna Casili, Michela Campolo, Emanuela Esposito
Antioxidants, 2023 - The Transcription Factor Nrf2 Mediates the Effects of Antrodia camphorata Extract on Neuropathological Changes in a Mouse Model of Parkinson’s Disease
Marika Lanza, Laura Cucinotta, Giovanna Casili, Alessia Filippone, Rossella Basilotta, Anna Paola Capra, Michela Campolo, Irene Paterniti, Salvatore Cuzzocrea, Emanuela Esposito
International Journal of Molecular Sciences, 2023 - Therapeutic Potential of BAY-117082, a Selective NLRP3 Inflammasome Inhibitor, on Metastatic Evolution in Human Oral Squamous Cell Carcinoma (OSCC)
Giovanna Casili, Sarah Adriana Scuderi, Marika Lanza, Alessia Filippone, Deborah Mannino, Raffaella Giuffrida, Cristina Colarossi, Marzia Mare, Anna Paola Capra, Federica De Gaetano, Marco Portelli, Angela Militi, Salvatore Cuzzocrea, Irene Paterniti, Emanuela Esposito
Cancers, 2023 - The Role of miR-128 in Neurodegenerative Diseases
Marika Lanza, Salvatore Cuzzocrea, Salvatore Oddo, Emanuela Esposito, Giovanna Casili
International Journal of Molecular Sciences, 2023 - Inhibition of LRRK2 Attenuates Depression-Related Symptoms in Mice with Moderate Traumatic Brain Injury
Alessia Filippone, Laura Cucinotta, Valentina Bova, Marika Lanza, Giovanna Casili, Irene Paterniti, Michela Campolo, Salvatore Cuzzocrea, Emanuela Esposito
Cells, 2023 - Role of Basic Fibroblast Growth Factor in Cancer: Biological Activity, Targeted Therapies, and Prognostic Value
Alessio Ardizzone, Valentina Bova, Giovanna Casili, Alberto Repici, Marika Lanza, Raffaella Giuffrida, Cristina Colarossi, Marzia Mare, Salvatore Cuzzocrea, Emanuela Esposito, Irene Paterniti
Cells, 2023 - Redox Imbalance in Neurological Disorders in Adults and Children
Federica Rey, Clarissa Berardo, Erika Maghraby, Alessia Mauri, Letizia Messa, Letizia Esposito, Giovanna Casili, Sara Ottolenghi, Eleonora Bonaventura, Salvatore Cuzzocrea, Gianvincenzo Zuccotti, Davide Tonduti, Emanuela Esposito, Irene Paterniti, Cristina Cereda, Stephana Carelli
Antioxidants, 2023 - Evaluation of the Efficacy of Xyloglucan, Pea Protein and Opuntia ficus-indica Extract in a Preclinical Model of Psoriasis
Alessia Filippone, Giovanna Casili, Marika Lanza, Sarah Adriana Scuderi, Alessio Ardizzone, Anna Paola Capra, Irene Paterniti, Michela Campolo, Salvatore Cuzzocrea, Emanuela Esposito
International Journal of Molecular Sciences, 2023 - Therapeutic Potential of Dimethyl Fumarate in Counteract Oral Squamous Cell Carcinoma Progression by Modulating Apoptosis, Oxidative Stress and Epithelial–Mesenchymal Transition
Rossella Basilotta, Marika Lanza, Alessia Filippone, Giovanna Casili, Deborah Mannino, Federica De Gaetano, Giulia Chisari, Lorenzo Colarossi, Gianmarco Motta, Michela Campolo, Salvatore Cuzzocrea, Irene Paterniti, Emanuela Esposito
International Journal of Molecular Sciences, 2023 - The Role of Neuro-Inflammation and Innate Immunity in Pathophysiology of Brain and Spinal Cord Tumors
Giovanna Casili, Irene Paterniti, Michela Campolo, Emanuela Esposito, Salvatore Cuzzocrea
Advances in Experimental Medicine and Biology, 2023 - Oxygen Sensing in Neurodegenerative Diseases: Current Mechanisms, Implication of Transcriptional Response, and Pharmacological Modulation
Federica Rey, Letizia Messa, Erika Maghraby, Giovanna Casili, Sara Ottolenghi, Bianca Barzaghini, Manuela Teresa Raimondi, Cristina Cereda, Salvatore Cuzzocrea, Gianvincenzo Zuccotti, Emanuela Esposito, Irene Paterniti, Stephana Carelli
Antioxidants and Redox Signaling, 2023 - Sodium Propionate Contributes to Tumor Cell Growth Inhibition through PPAR-γ Signaling
Alessia Filippone, Giovanna Casili, Sarah Adriana Scuderi, Deborah Mannino, Marika Lanza, Michela Campolo, Irene Paterniti, Anna Paola Capra, Cristina Colarossi, Annalisa Bonasera, Sofia Paola Lombardo, Salvatore Cuzzocrea, Emanuela Esposito
Cancers, 2023 - A New Approach for the Treatment of Recurrent Vulvovaginal Candidiasis with a Combination of Pea Protein, Grape Seed Extract, and Lactic Acid Assessed In Vivo
Irene Paterniti, Giovanna Casili, Alessia Filippone, Marika Lanza, Alessio Ardizzone, Anna Paola Capra, Michela Campolo, Emanuela Esposito
Journal of Fungi, 2022 - SUN11602, a bFGF mimetic, modulated neuroinflammation, apoptosis and calcium-binding proteins in an in vivo model of MPTP-induced nigrostriatal degeneration
Alessio Ardizzone, Valentina Bova, Giovanna Casili, Alessia Filippone, Michela Campolo, Marika Lanza, Emanuela Esposito, Irene Paterniti
Journal of Neuroinflammation, 2022 - BAY-117082-driven NLRP3 inflammasome inhibition resolves nitro-glycerine (NTG) neuronal damage in in vivo model of migraine
Alessia Filippone, Sarah Adriana Scuderi, Rossella Basilotta, Marika Lanza, Giovanna Casili, Valentina Bova, Irene Paterniti, Emanuela Esposito
Biomedicine and Pharmacotherapy, 2022 - A Combination of Xyloglucan, Pea Protein and Chia Seed Ameliorates Intestinal Barrier Integrity and Mucosa Functionality in a Rat Model of Constipation-Predominant Irritable Bowel Syndrome
Alessia Filippone, Alessio Ardizzone, Valentina Bova, Marika Lanza, Giovanna Casili, Salvatore Cuzzocrea, Emanuela Esposito, Michela Campolo, Irene Paterniti
Journal of Clinical Medicine, 2022 - Overview on Common Genes Involved in the Onset of Glioma and on the Role of Migraine as Risk Factor: Predictive Biomarkers or Therapeutic Targets?
Giovanna Casili, Marika Lanza, Alessia Filippone, Maria Caffo, Irene Paterniti, Michela Campolo, Lorenzo Colarossi, Dorotea Sciacca, Sofia Paola Lombardo, Salvatore Cuzzocrea, Emanuela Esposito
Journal of Personalized Medicine, 2022 - Protein Kinase Inhibitors as a New Target for Immune System Modulation and Brain Cancer Management
Alessia Filippone, Deborah Mannino, Giovanna Casili, Marika Lanza, Irene Paterniti, Salvatore Cuzzocrea, Anna Paola Capra, Lorenzo Colarossi, Dario Giuffrida, Sofia Paola Lombardo, Emanuela Esposito
International Journal of Molecular Sciences, 2022 - The Pivotal Role of Protein Phosphatase 2A (PP2A) in Brain Tumors
Laura Cucinotta, Alessia Filippone, Giovanna Casili, Marika Lanza, Valentina Bova, Anna Paola Capra, Raffaella Giuffrida, Cristina Colarossi, Dorotea Sciacca, Irene Paterniti, Salvatore Cuzzocrea, Michela Campolo, Emanuela Esposito
International Journal of Molecular Sciences, 2022 - GSK343, an Inhibitor of Enhancer of Zeste Homolog 2, Reduces Glioblastoma Progression through Inflammatory Process Modulation: Focus on Canonical and Non-Canonical NF-κB/IκBα Pathways
Sarah Adriana Scuderi, Alessia Filippone, Rossella Basilotta, Deborah Mannino, Giovanna Casili, Anna Paola Capra, Giulia Chisari, Lorenzo Colarossi, Serena Sava, Michela Campolo, Emanuela Esposito, Irene Paterniti
International Journal of Molecular Sciences, 2022 - Dimethyl Fumarate (DMF) Alleviated Post-Operative (PO) Pain through the N-Methyl-d-Aspartate (NMDA) Receptors
Giovanna Casili, Marika Lanza, Alessia Filippone, Laura Cucinotta, Irene Paterniti, Alberto Repici, Anna Paola Capra, Salvatore Cuzzocrea, Emanuela Esposito, Michela Campolo
Antioxidants, 2022 - Inhibition of the 3-mercaptopyruvate sulfurtransferase—hydrogen sulfide system promotes cellular lipid accumulation
Giovanna Casili, Elisa Randi, Theodora Panagaki, Karim Zuhra, Maria Petrosino, Csaba Szabo
Geroscience, 2022 - Ulva pertusa, a Marine Green Alga, Attenuates DNBS-Induced Colitis Damage via NF-κB/Nrf2/SIRT1 Signaling Pathways
Alessio Ardizzone, Alessia Filippone, Deborah Mannino, Sarah Adriana Scuderi, Giovanna Casili, Marika Lanza, Laura Cucinotta, Michela Campolo, Emanuela Esposito
Journal of Clinical Medicine, 2022 - Adenosine Targeting as a New Strategy to Decrease Glioblastoma Aggressiveness
Valentina Bova, Alessia Filippone, Giovanna Casili, Marika Lanza, Michela Campolo, Anna Paola Capra, Alberto Repici, Lelio Crupi, Gianmarco Motta, Cristina Colarossi, Giulia Chisari, Salvatore Cuzzocrea, Emanuela Esposito, Irene Paterniti
Cancers, 2022 - Efficacy of a Novel Therapeutic, Based on Natural Ingredients and Probiotics, in a Murine Model of Multiple Food Intolerance and Maldigestion
Alessio Ardizzone, Marika Lanza, Giovanna Casili, Michela Campolo, Irene Paterniti, Salvatore Cuzzocrea, Emanuela Esposito
Nutrients, 2022 - Supplementation with SCFAs Re‐Establishes Microbiota Composition and Attenuates Hyperalgesia and Pain in a Mouse Model of NTG‐Induced Migraine
Marika Lanza, Alessia Filippone, Giovanna Casili, Letterio Giuffrè, Sarah Adriana Scuderi, Irene Paterniti, Michela Campolo, Salvatore Cuzzocrea, Emanuela Esposito
International Journal of Molecular Sciences, 2022 - Potential Therapeutic Effects of PPAR Ligands in Glioblastoma
Rossella Basilotta, Marika Lanza, Giovanna Casili, Giulia Chisari, Stefania Munao, Lorenzo Colarossi, Laura Cucinotta, Michela Campolo, Emanuela Esposito, Irene Paterniti
Cells, 2022 - RETRACTED: Efficacy of a Product Containing Xyloglucan and Pea Protein on Intestinal Barrier Function in a Partial Restraint Stress Animal Model
Sarah Adriana Scuderi, Giovanna Casili, Marika Lanza, Alessio Ardizzone, Luca Pantaleo, Michela Campolo, Irene Paterniti, Laura Cucinotta, Salvatore Cuzzocrea, Emanuela Esposito
International Journal of Molecular Sciences, 2022 - Beneficial effect of KYP-2047, a propyl-oligopeptidase inhibitor, on oral squamous cell carcinoma
Sarah Adriana Scuderi, Giovanna Casili, Alessia Filippone, Marika Lanza, Rossella Basilotta, Raffaella Giuffrida, Stefania Munaò, Lorenzo Colarossi, Anna Paola Capra, Emanuela Esposito, Irene Paterniti
Oncotarget, 2021 - The protective role of prolyl oligopeptidase (Pop) inhibition in kidney injury induced by renal ischemia–reperfusion
Giovanna Casili, Alessio Ardizzone, Rossella Basilotta, Marika Lanza, Alessia Filippone, Irene Paterniti, Emanuela Esposito, Michela Campolo
International Journal of Molecular Sciences, 2021 - Nlrp3 inflammasome inhibitor bay-117082 reduces oral squamous cell carcinoma progression
Sarah Adriana Scuderi, Giovanna Casili, Rossella Basilotta, Marika Lanza, Alessia Filippone, Gabriele Raciti, Ivana Puliafito, Lorenzo Colarossi, Emanuela Esposito, Irene Paterniti
International Journal of Molecular Sciences, 2021 - SCFA treatment alleviates pathological signs of migraine and related intestinal alterations in a mouse model of NTG-induced migraine
Marika Lanza, Alessia Filippone, Alessio Ardizzone, Giovanna Casili, Irene Paterniti, Emanuela Esposito, Michela Campolo
Cells, 2021 - Evaluating the protective properties of a xyloglucan-based nasal spray in a mouse model of allergic rhinitis
Marika Lanza, Giovanna Casili, Alessia Filippone, Michela Campolo, Irene Paterniti, Salvatore Cuzzocrea, Emanuela Esposito
International Journal of Molecular Sciences, 2021 - Inhibition of prolyl oligopeptidase prevents consequences of reperfusion following intestinal ischemia
Alessia Filippone, Giovanna Casili, Alessio Ardizzone, Marika Lanza, Deborah Mannino, Irene Paterniti, Emanuela Esposito, Michela Campolo
Biomedicines, 2021 - Co-ultra PEALut enhances endogenous repair response following moderate traumatic brain injury
Michela Campolo, Rosalia Crupi, Marika Cordaro, Salvatore Massimo Cardali, Alessio Ardizzone, Giovanna Casili, Sarah Adriana Scuderi, Rosalba Siracusa, Emanuela Esposito, Alfredo Conti, Salvatore Cuzzocrea
International Journal of Molecular Sciences, 2021 - The protective role of prolyl oligopeptidase (pop) inhibition in acute lung injury induced by intestinal ischemia-reperfusion
Giovanna Casili, Sarah Adriana Scuderi, Marika Lanza, Alessia Filippone, Rossella Basilotta, Deborah Mannino, Michela Campolo, Emanuela Esposito, Irene Paterniti
Oncotarget, 2021 - The inhibition of mammalian target of rapamycin (mTOR) in improving inflammatory response after traumatic brain injury
Michela Campolo, Giovanna Casili, Marika Lanza, Alessia Filippone, Marika Cordaro, Alessio Ardizzone, Sarah Adriana Scuderi, Salvatore Cuzzocrea, Emanuela Esposito, Irene Paterniti
Journal of Cellular and Molecular Medicine, 2021 - KYP-2047, an inhibitor of prolyl-oligopeptidase, reduces glioblastoma proliferation through angiogenesis and apoptosis modulation
Sarah Adriana Scuderi, Giovanna Casili, Alessio Ardizzone, Stefano Forte, Lorenzo Colarossi, Serena Sava, Irene Paterniti, Emanuela Esposito, Salvatore Cuzzocrea, Michela Campolo
Cancers, 2021 - Role of calixarene in chemotherapy delivery strategies
Rossella Basilotta, Deborah Mannino, Alessia Filippone, Giovanna Casili, Angela Prestifilippo, Lorenzo Colarossi, Gabriele Raciti, Emanuela Esposito, Michela Campolo
Molecules, 2021 - Poly (Adp-ribose) polymerase inhibitor, abt888, improved cisplatin effect in human oral cell carcinoma
Irene Paterniti, Sarah Adriana Scuderi, Giovanna Casili, Marika Lanza, Marzia Mare, Raffella Giuffrida, Cristina Colarossi, Marco Portelli, Salvatore Cuzzocrea, Emanuela Esposito
Biomedicines, 2021 - Pea-oxa mitigates oxaliplatin-induced painful neuropathy through nf-κb/nrf-2 axis
Michela Campolo, Marika Lanza, Irene Paterniti, Alessia Filippone, Alessio Ardizzone, Giovanna Casili, Sarah A. Scuderi, Caterina Puglisi, Marzia Mare, Lorenzo Memeo, Salvatore Cuzzocrea, Emanuela Esposito
International Journal of Molecular Sciences, 2021 - Therapeutic potential of flavonoids in the treatment of chronic venous insufficiency
Giovanna Casili, Marika Lanza, Michela Campolo, Salvatore Messina, Sarah Scuderi, Alessio Ardizzone, Alessia Filippone, Irene Paterniti, Salvatore Cuzzocrea, Emanuela Esposito
Vascular Pharmacology, 2021 - Selenium-binding protein 1 (Selenbp1) supports hydrogen sulfide biosynthesis and adipogenesis
Elisa B. Randi, Giovanna Casili, Simona Jacquemai, Csaba Szabo
Antioxidants, 2021 - Effect of ultra-micronized-palmitoylethanolamide and acetyl-l-carnitine on experimental model of inflammatory pain
Alessio Ardizzone, Roberta Fusco, Giovanna Casili, Marika Lanza, Daniela Impellizzeri, Emanuela Esposito, Salvatore Cuzzocrea
International Journal of Molecular Sciences, 2021 - Immunomodulatory effect of microglia-released cytokines in gliomas
Marika Lanza, Giovanna Casili, Michela Campolo, Irene Paterniti, Cristina Colarossi, Marzia Mare, Raffella Giuffrida, Maria Caffo, Emanuela Esposito, Salvatore Cuzzocrea
Brain Sciences, 2021 - TBK1 Inhibitor exerts antiproliferative effect on glioblastoma multiforme cells
Sarah A. Scuderi, Marika Lanza, Giovanna Casili, Francesca Esposito, Cristina Colarossi, Dario Giuffrida, Paterniti Irene, Salvatore Cuzzocrea, Emanuela Esposito, Michela Campolo
Oncology Research, 2021 - TAK1 inhibitor enhances the therapeutic treatment for glioblastoma
Michela Campolo, Marika Lanza, Giovanna Casili, Irene Paterniti, Alessia Filippone, Maria Caffo, Salvatore M. Cardali, Ivana Puliafito, Cristina Colarossi, Gabriele Raciti, Salvatore Cuzzocrea, Emanuela Esposito
Cancers, 2021 - Tlr7/8 in the pathogenesis of parkinson’s disease
Michela Campolo, Alessia Filippone, Carmelo Biondo, Giuseppe Mancuso, Giovanna Casili, Marika Lanza, Salvatore Cuzzocrea, Emanuela Esposito, Irene Paterniti
International Journal of Molecular Sciences, 2020 - The inhibition of prolyl oligopeptidase as new target to counteract chronic venous insufficiency: Findings in a mouse model
Giovanna Casili, Marika Lanza, Sarah Adriana Scuderi, Salvatore Messina, Irene Paterniti, Michela Campolo, Emanuela Esposito
Biomedicines, 2020 - Efficacy of Xyloglucan against Escherichia coli Extraintestinal Urinary Tract Infection: An in vivo Study
Emanuela Esposito, Michela Campolo, Giovanna Casili, Marika Lanza, Domenico Franco, Enza Fazio, Alessia Filippone, Irene Paterniti, Salvatore Cuzzocrea
Microbial Physiology, 2020 - Modulation of nlrp3 inflammasome attenuated inflammatory response associated to diarrhea-predominant irritable bowel syndrome
Sarah Adriana Scuderi, Giovanna Casili, Marika Lanza, Alessia Filippone, Irene Paterniti, Emanuela Esposito, Michela Campolo
Biomedicines, 2020 - Role of ABT888, a Novel Poly(ADP-Ribose) Polymerase (PARP) Inhibitor in Countering Autophagy and Apoptotic Processes Associated to Spinal Cord Injury
Giovanna Casili, Michela Campolo, Marika Lanza, Alessia Filippone, Sarah Scuderi, Salvatore Messina, Alessio Ardizzone, Emanuela Esposito, Irene Paterniti
Molecular Neurobiology, 2020 - Synergic therapeutic potential of PEA-Um treatment and NAAA enzyme silencing in the management of neuroinflammation
Giovanna Casili, Marika Lanza, Michela Campolo, Rosalba Siracusa, Irene Paterniti, Alessio Ardizzone, Sarah Adriana Scuderi, Salvatore Cuzzocrea, Emanuela Esposito
International Journal of Molecular Sciences, 2020 - Evaluation of a Product Containing Xyloglucan and Pea Protein on Skin Barrier Permeability
Michela Campolo, Marika Lanza, Alessia Filippone, Irene Paterniti, Giovanna Casili, Sarah A. Scuderi, Alessio Ardizzone, Salvatore Cuzzocrea, Emanuela Esposito
Skin Pharmacology and Physiology, 2020 - Treatment with luteolin improves lipopolysaccharide‐induced periodontal diseases in rats
Giovanna Casili, Alessio Ardizzone, Marika Lanza, Enrico Gugliandolo, Marco Portelli, Angela Militi, Salvatore Cuzzocrea, Emanuela Esposito, Irene Paterniti
Biomedicines, 2020 - Properties of a new food supplement containing actinia equina extract
Marika Lanza, Giovanna Casili, Giovanna Loredana La Torre, Daniele Giuffrida, Archimede Rotondo, Emanuela Esposito, Alessio Ardizzone, Rossana Rando, Giovanni Bartolomeo, Ambrogina Albergamo, Rossella Vadalà, Andrea Salvo
Antioxidants, 2020 - Topical delivery of curcumin by choline-calix[4]arene-based nanohydrogel improves its therapeutic effect on a psoriasis mouse model
Alessia Filippone, Grazia M. L. Consoli, Giuseppe Granata, Giovanna Casili, Marika Lanza, Alessio Ardizzone, Salvatore Cuzzocrea, Emanuela Esposito, Irene Paterniti
International Journal of Molecular Sciences, 2020 - Effect of a product containing xyloglucan and pea protein on a murine model of atopic dermatitis
Michela Campolo, Giovanna Casili, Irene Paterniti, Alessia Filippone, Marika Lanza, Alessio Ardizzone, Sarah A Scuderi, Salvatore Cuzzocrea, Emanuela Esposito
International Journal of Molecular Sciences, 2020 - The anti-inflammatory and antioxidant effects of sodium propionate
Alessia Filippone, Marika Lanza, Michela Campolo, Giovanna Casili, Irene Paterniti, Salvatore Cuzzocrea, Emanuela Esposito
International Journal of Molecular Sciences, 2020 - Protective effect of sodium propionate in Aβ1-42 -induced neurotoxicity and spinal cord trauma
A. Filippone, M. Lanza, M. Campolo, G. Casili, I. Paterniti, S. Cuzzocrea, E. Esposito
Neuropharmacology, 2020 - Neutralization of extracellular NAMPT (nicotinamide phosphoribosyltransferase) ameliorates experimental murine colitis
Giorgia Colombo, Nausicaa Clemente, Andrea Zito, Cristiano Bracci, Federico Simone Colombo, Sabina Sangaletti, Elena Jachetti, Davide Giuseppe Ribaldone, Gian Paolo Caviglia, Luca Pastorelli, Marco De Andrea, Samuele Naviglio, Marianna Lucafò, Gabriele Stocco, Ambra A. Grolla, Michela Campolo, Giovanna Casili, Salvatore Cuzzocrea, Emanuela Esposito, Fabio Malavasi, Armando A. Genazzani, Chiara Porta, Cristina Travelli
Journal of Molecular Medicine, 2020 - Dimethyl fumarate alleviates the nitroglycerin (NTG)-induced migraine in mice
Giovanna Casili, Marika Lanza, Alessia Filippone, Michela Campolo, Irene Paterniti, Salvatore Cuzzocrea, Emanuela Esposito
Journal of Neuroinflammation, 2020 - Sodium Butyrate Exerts Neuroprotective Effects in Spinal Cord Injury
M. Lanza, M. Campolo, G. Casili, A. Filippone, I. Paterniti, S. Cuzzocrea, Emanuela Esposito
Molecular Neurobiology, 2019 - TLR-4/Wnt modulation as new therapeutic strategy in the treatment of glioblastomas
Giovanna Casili, Maria Caffo, Michela Campolo, Valeria Barresi, Gerardo Caruso, Salvatore M. Cardali, Marika Lanza, Raffaella Mallamace, Alessia Filippone, Alfredo Conti, Antonino Germanò, Salvatore Cuzzocrea, Emanuela Esposito
Oncotarget, 2018 - N-palmitoylethanolamide Prevents Parkinsonian Phenotypes in Aged Mice
Rosalia Crupi, Daniela Impellizzeri, Marika Cordaro, Rosalba Siracusa, Giovanna Casili, Maurizio Evangelista, Salvatore Cuzzocrea
Molecular Neurobiology, 2018 - Effect of pea protein plus grape seed dry extract on a murine model of Candida albicans induced vaginitis
Emanuela Esposito, Michela Campolo, Giovanna Casili, Marika Lanza, Alessia Filippone, Alessio F Peritore, Salvatore Cuzzocrea
Future Microbiology, 2018 - Dimethyl Fumarate Attenuates Neuroinflammation and Neurobehavioral Deficits Induced by Experimental Traumatic Brain Injury
Giovanna Casili, Michela Campolo, Irene Paterniti, Marika Lanza, Alessia Filippone, Salvatore Cuzzocrea, Emanuela Esposito
Journal of Neurotrauma, 2018 - Protective effects of xyloglucan in association with the polysaccharide gelose in an experimental model of gastroenteritis and urinary tract infections
Emanuela Esposito, Michela Campolo, Giovanna Casili, Marika Lanza, Domenico Franco, Alessia Filippone, Alessio F. Peritore, Salvatore Cuzzocrea
International Journal of Molecular Sciences, 2018 - Multiple mechanisms of dimethyl fumarate in amyloid β-induced neurotoxicity in human neuronal cells
Michela Campolo, Giovanna Casili, Marika Lanza, Alessia Filippone, Irene Paterniti, Salvatore Cuzzocrea, Emanuela Esposito
Journal of Cellular and Molecular Medicine, 2018 - Fumaric Acid Esters Attenuate Secondary Degeneration after Spinal Cord Injury
Marika Cordaro, Giovanna Casili, Irene Paterniti, Salvatore Cuzzocrea, Emanuela Esposito
Journal of Neurotrauma, 2017 - The Neuroprotective Effect of Dimethyl Fumarate in an MPTP-Mouse Model of Parkinson's Disease: Involvement of Reactive Oxygen Species/Nuclear Factor-κB/Nuclear Transcription Factor Related to NF-E2
Michela Campolo, Giovanna Casili, Flavia Biundo, Rosalia Crupi, Marika Cordaro, Salvatore Cuzzocrea, Emanuela Esposito
Antioxidants and Redox Signaling, 2017 - Modulation of Dkk-3 and claudin-5 as new therapeutic strategy in the treatment of meningiomas
Maria Caffo, Emanuela Esposito, Valeria Barresi, Gerardo Caruso, Salvatore M. Cardali, Mariagrazia Rinaldi, Raffaella Mallamace, Michela Campolo, Giovanna Casili, Alfredo Conti, Antonino Germanò, Salvatore Cuzzocrea, Letteria Minutoli
Oncotarget, 2017 - FeTPPS reduces secondary damage and improves neurobehavioral functions after traumatic brain injury
Giuseppe Bruschetta, Daniela Impellizzeri, Michela Campolo, Giovanna Casili, Rosanna Di Paola, Irene Paterniti, Emanuela Esposito, Salvatore Cuzzocrea
Frontiers in Neuroscience, 2017 - Adelmidrol, a palmitoylethanolamide analogue, as a new pharmacological treatment for the management of acute and chronic inflammation
Daniela Impellizzeri, Rosanna Di Paola, Marika Cordaro, Enrico Gugliandolo, Giovanna Casili, Valeria Maria Morittu, Domenico Britti, Emanuela Esposito, Salvatore Cuzzocrea
Biochemical Pharmacology, 2016 - B-Cell Depletion with CD20 Antibodies as New Approach in the Treatment of Inflammatory and Immunological Events Associated with Spinal Cord Injury
Giovanna Casili, Daniela Impellizzeri, Marika Cordaro, Emanuela Esposito, Salvatore Cuzzocrea
Neurotherapeutics, 2016 - Dimethyl fumarate reduces inflammatory responses in experimental colitis
Giovanna Casili, Marika Cordaro, Daniela Impellizzeri, Giuseppe Bruschetta, Irene Paterniti, Salvatore Cuzzocrea, Emanuela Esposito
Journal of Crohn S and Colitis, 2016 - Reply: Pitfalls in management of postoperative takotsubo cardiomyopathy: Trying to put out the fire
Giordano Zampi, Amedeo Pergolini, Daniele Pontillo, Francesco Musumeci
Journal of Cardiothoracic and Vascular Anesthesia, 2014
