Ilenia Folletti

@unipg.it

Department of Medicine and Surgeon
University of Perugia

EDUCATION

Graduated from the University of Perugia Medical School on October 22, 1998.
· Began his residency in Occupational Medicine in 1999 at the University of Perugia.
· Completed residency in Occupational Medicine cum laude in 2003 at the University of Perugia.

. Visiting Fellow in the Environmental Epidemiology Centre for Research in Environmental Epidemiology (CREAL), Barcelona in 2012, Research Fellow in Occupational Medicine at the .
. Attendance at the Residential summer course of the European Educational Program in Epidemiology (E.E.P.E.),; Florence, Italy, 26 June- 14 July 2006.
. Attendance of the course “Epidemiologia in azione. Utilizzare i dati esistenti e raccogliere i dati che non esistono per sviluppo e monitoraggio di interventi efficaci in sanità pubblica”, Istituto Superiore di Sanità, Orvieto 7-18 maggio 2007

RESEARCH, TEACHING, or OTHER INTERESTS

Public Health, Environmental and Occupational Health, Pulmonary and Respiratory Medicine, Pulmonary and Respiratory Medicine, Epidemiology
66

Scopus Publications

Scopus Publications

  • Occupational Asthma Without Nonspecific Bronchial Hyperresponsiveness
    Virginie Doyen, Julien Godet, Jolanta Walusiak-Skorupa, Marta Wiszniewska, Joaquin Sastre, Marcela Valverde-Monge, Hille Suojalehto, Xavier Munoz, Christian Romero-Mesones, Vera van Kampen, Christian Eisenhawer, Gareth Walters, Vicky Moore, Paola Mason, Frédéric de Blay, Santiago Quirce, Ilenia Folletti, Catherine Rifflart, Olivier Vandenplas
    Journal of Allergy and Clinical Immunology in Practice, 2026
  • Occupational Asthma Due to Hair Dyes Containing Para-Amino Compounds
    Virginie Doyen, Jolanta Walusiak‐Skorupa, Marta Wiszniewska, Olivier Vandenplas, Katri Suuronen, Joaquin Sastre, Cecilie Svanes, Ilenia Folletti, Xavier Munoz, Frédéric de Blay, Catherine Rifflart, Martin Seed, Hille Suojalehto
    American Journal of Industrial Medicine, 2026
    Background Persulfate salts in hair bleaches are a well‐documented cause of occupational asthma (OA) among hairdressers, but little information is available on OA caused by hair products containing other low‐molecular‐weight chemicals. The aim of this study was to investigate the prevalence and clinical characteristics of OA caused by oxidative hair dyes containing para‐amino compounds (PACs). Methods This retrospective multicenter study was conducted among 98 hairdressers with OA ascertained by a positive specific inhalation challenge (SIC) with hair products completed between 2006 and 2018 in 14 European tertiary centers. Nine hairdressers (9%) with a positive SIC response to hair dyes containing PACs were identified and reviewed. Results Eight hairdressers developed a bronchial response during “work‐simulation” SICs with hair dyes used at work, whereas one subject was challenged with pure para‐phenylene diamine. The pattern of bronchial reactions was isolated late, dual, and isolated early in four, three, and two subjects, respectively. A significant post‐challenge increase in nonspecific airway hyperresponsiveness was detected in three of the seven (43%) subjects with both pre‐ and post‐SIC measurements available. Among subjects with fractional exhaled nitric oxide measurements ( n = 3) or sputum eosinophil counts ( n = 4) available both before and after the SIC, none showed a significant increase in these airway inflammatory markers. Conclusions Hair dyes containing PACs may contribute substantially to OA among hairdressers. This possibility should be considered carefully when evaluating hairdressers with work‐related asthma symptoms. However, there is a need for further investigation of the underlying inflammatory and immunological mechanisms.
  • Phenotypic Characteristics of Occupational Asthma Caused by Persulfate Salts in Hairdressers: A Multicenter Cohort Study
    Virginie Doyen, Robin Thirionet, Nicolas Migueres, Olivier Vandenplas, Joaquin Sastre, Marcela Valverde-Monge, Thomas Blix Grydeland, Xavier Munoz, Christian Romero-Mesones, Hille Suojalehto, Katri Suuronen, Vera van Kampen, Christian Eisenhawer, Ilenia Folletti, Iben Brock Jacobsen, Jolanta Walusiak-Skorupa, Paola Mason, Alexandra M. Preiser, Santiago Quirce, Gareth Walters, Catherine Rifflart, Frédéric de Blay, Cecilie Svanes
    Journal of Allergy and Clinical Immunology in Practice, 2025
  • Exhaled Nitric Oxide and Sputum Eosinophils Are Complementary Tools for Diagnosing Occupational Asthma
    Virginie Doyen, Nicolas Migueres, Vera van Kampen, Hille Suojalehto, Paola Mason, Xavier Munoz, Joaquin Sastre, Santiago Quirce, Cecilie Svanes, Gareth Walters, Vicky Moore, Iben Brock Jacobsen, Ilenia Folletti, Alexandra M. Preiser, Jolanta Walusiak‐Skorupa, Catherine Rifflart, Frédéric de Blay, Olivier Vandenplas, and
    Allergy European Journal of Allergy and Clinical Immunology, 2025
    BackgroundExposure‐related changes in exhaled nitric oxide (FeNO) and sputum eosinophils have not been thoroughly compared in the investigation of occupational asthma.ObjectiveThis study aimed at comparing the accuracies of the changes in FeNO concentrations and sputum eosinophil counts in identifying asthmatic reactions induced by occupational agents during specific inhalation challenges (SICs).MethodsThis retrospective multicenter study included 321 subjects who completed an assessment of FeNO and sputum eosinophils before and 24 h after SICs with various occupational agents, of whom 156 showed a positive result.ResultsPost‐challenge changes in FeNO and sputum eosinophils showed similar accuracies, with areas under the receiver operating characteristics curve of 0.78 (95% confidence interval [95% CI], 0.72–0.83) and 0.81 (95% CI, 0.76–0.86), respectively. Increases in FeNO level ≥ 13 ppb and sputum eosinophils ≥ 1.25% were identified as the optimal threshold values for differentiating positive from negative SICs. Using these thresholds, the changes in FeNO and sputum eosinophils each achieved a ≥ 95% specificity but a low sensitivity (55% and 62%, respectively). FeNO and sputum eosinophils showed discordant increases in 38% of subjects with a positive SIC. Combining either a rise in FeNO ≥ 13 ppb or an increase in sputum eosinophils ≥ 1.25% increased the sensitivity to 77%.ConclusionsIncreases in FeNO concentration and/or sputum eosinophils after exposure to occupational agents strongly support a diagnosis of occupational asthma. The assessment of both markers of airway inflammation should be regarded as a reliable complementary tool to spirometry for identifying bronchial responses to occupational agents.
  • Occupational Rhinoconjunctivitis Induced by Flaxseed: Identification of Novel Allergenic Proteins From Cupin, Chaperonin, and Enzyme Families
    A Gambelunghe, E Chiaradia, S Buratta, E Calzoni, A Tognoloni, E Prosperi, A Giuliani, C Emiliani, M dell’Omo, I Folletti
    Journal of Investigational Allergology and Clinical Immunology, 2025
    not available
  • Modelling the long-term health impact of COVID-19 using Graphical Chain Models brief heading: long COVID prediction by graphical chain models
    K. Gourgoura, P. Rivadeneyra, E. Stanghellini, C. Caroni, F. Bartolucci, R. Curcio, S. Bartoli, R. Ferranti, I. Folletti, M. Cavallo, L. Sanesi, I. Dominioni, E. Santoni, G. Morgana, M. B. Pasticci, G. Pucci, G. Vaudo
    BMC Infectious Diseases, 2024
    Long-term sequelae of SARS-CoV-2 infection, namely long COVID syndrome, affect about 10% of severe COVID-19 survivors. This condition includes several physical symptoms and objective measures of organ dysfunction resulting from a complex interaction between individual predisposing factors and the acute manifestation of disease. We aimed at describing the complexity of the relationship between long COVID symptoms and their predictors in a population of survivors of hospitalization for severe COVID-19-related pneumonia using a Graphical Chain Model (GCM). 96 patients with severe COVID-19 hospitalized in a non-intensive ward at the “Santa Maria” University Hospital, Terni, Italy, were followed up at 3–6 months. Data regarding present and previous clinical status, drug treatment, findings recorded during the in-hospital phase, presence of symptoms and signs of organ damage at follow-up were collected. Static and dynamic cardiac and respiratory parameters were evaluated by resting pulmonary function test, echocardiography, high-resolution chest tomography (HRCT) and cardiopulmonary exercise testing (CPET). Twelve clinically most relevant factors were identified and partitioned into four ordered blocks in the GCM: block 1 - gender, smoking, age and body mass index (BMI); block 2 - admission to the intensive care unit (ICU) and length of follow-up in days; block 3 - peak oxygen consumption (VO2), forced expiratory volume at first second (FEV1), D-dimer levels, depression score and presence of fatigue; block 4 - HRCT pathological findings. Higher BMI and smoking had a significant impact on the probability of a patient’s admission to ICU. VO2 showed dependency on length of follow-up. FEV1 was related to the self-assessed indicator of fatigue, and, in turn, fatigue was significantly associated with the depression score. Notably, neither fatigue nor depression depended on variables in block 2, including length of follow-up. The biological plausibility of the relationships between variables demonstrated by the GCM validates the efficacy of this approach as a valuable statistical tool for elucidating structural features, such as conditional dependencies and associations. This promising method holds potential for exploring the long-term health repercussions of COVID-19 by identifying predictive factors and establishing suitable therapeutic strategies.
  • Correction to: Modelling the long-term health impact of COVID-19 using Graphical Chain Models (BMC Infectious Diseases, (2024), 24, 1, (885), 10.1186/s12879-024-09777-0)
    K. Gourgoura, P. Rivadeneyra, E. Stanghellini, C. Caroni, F. Bartolucci, R. Curcio, S. Bartoli, R. Ferranti, I. Folletti, M. Cavallo, L. Sanesi, I. Dominioni, E. Santoni, G. Morgana, M. B. Pasticci, G. Pucci, G. Vaudo
    BMC Infectious Diseases, 2024
  • Exosomal miR-17-5p, miR-146a-3p, and miR-223-3p Correlate with Radiologic Sequelae in Survivors of COVID-19-Related Acute Respiratory Distress Syndrome
    Rosa Curcio, Giulia Poli, Consuelo Fabi, Chiara Sugoni, Maria Bruna Pasticci, Roberto Ferranti, Monica Rossi, Ilenia Folletti, Leandro Sanesi, Edoardo Santoni, Irene Dominioni, Massimiliano Cavallo, Giovanni Morgana, Lorenzo Mordeglia, Giovanni Luca, Giacomo Pucci, Stefano Brancorsini, Gaetano Vaudo
    International Journal of Molecular Sciences, 2023
    We investigated the association between circulating microRNAs (miRNAs) potentially involved in the lung inflammatory process and fibrosis development among COVID-19-related acute respiratory distress syndrome (ARDS) survivors. At 4 ± 2 months from clinical recovery, COVID-19-related ARDS survivors matched for age, sex, and clinical characteristics underwent chest high-resolution computerized tomography (HRCT) and were selected based on imaging pattern evolution into fully recovered (N = normal), pulmonary opacities (PO) and fibrosis-like lesions (FL). Based on the previous literature, we performed plasma miRNA profiling of exosomal miRNAs belonging to the NLRP3-inflammasome platform with validated (miR-17-5p, miR-223-3p) and putative targets (miR-146a-5p), miRNAs involved in the post-transcriptional regulation of acute phase cytokines (miR128-3p, miR3168, miR125b-2-3p, miR106a-5p), miRNAs belonging to the NLRP4-inflammasome platform (miR-141-3p) and miRNAs related to post-transcriptional regulation of the fibrosis process (miR-21-5p). miR-17-5p, miR-223-3p, and miR-146a-5p were significantly down-regulated in patients with FL when compared to patients with PO. miR-146a-5p was also down-regulated in patients with FL than in N. The expression of the remaining miRNAs did not differ by group. In patients with long-term pulmonary radiological sequelae following COVID-19-related ARDS, a down-regulation of miR-17-5p, miR-146a-3p, and miR-223-3p correlated to fibrosis development in patients showing persistent hyper-reactivity to inflammatory stimulation. Our results support the hypothesis that NLRP3-Inflammasome could be implicated in the process of fibrotic evolution of COVID-19-associated ARDS.
  • Incidence and Determinants of Symptomatic and Asymptomatic SARS-CoV-2 Breakthrough Infections After Booster Dose in a Large European Multicentric Cohort of Health Workers-ORCHESTRA Project
    Stefano Porru, Maria Grazia Lourdes Monaco, Gianluca Spiteri, Angela Carta, Gulser Caliskan, Concepción Violán, Pere Torán-Monserrat, Luigi Vimercati, Silvio Tafuri, Paolo Boffetta, Francesco Saverio Violante, Emma Sala, Emanuele Sansone, Fabriziomaria Gobba, Loretta Casolari, Andreas Wieser, Christian Janke, Adonina Tardon, Marta Maria Rodriguez-Suarez, Filippo Liviero, Maria Luisa Scapellato, Marco dell’Omo, Nicola Murgia, Dana Mates, Violeta Claudia Calota, Jozef Strhársky, Mariana Mrázová, Enrico Pira, Alessandro Godono, Greta Camilla Magnano, Corrado Negro, Giuseppe Verlato, Maria Diletta Pezzani, Evelina Tacconelli, Davide Gibellini, Virginia Lotti, Lucí Amalia Carrasco-Ribelles, Eva María Martínez Cácers, Julia Garcia Prado, Noemí Lamonja-Vicente, Luigi De Maria, Pasquale Stefanizzi, Stefania Sponselli, Antonio Caputi, Mahsa Abedini, Giorgia Ditano, Shuffield S. Asafo, Giulia Collatuzzo, Giuseppe De Palma, Alberto Modenese, Giorgia Rossi, Francesca Glieca, Daniela Vivoli, Michael Hoelscher, Noemi Castelletti, Christina Reinkemeyer, Thu Giang Le Thi, Guillermo Fernandez-Tardon, Pedro Ignacio Arcos-Gonzalez, Francisco José Jimeno-Demuth, Carmen Natal-Ramos, Angelo Moretto, Paola Mason, Sofia Pavanello, Anna Volpin, Giacomo Muzi, Angela Gambelunghe, Ilenia Folletti, Tiziana Fiordi, Andra Neamtu, Ovidiu Perseca, Catalin Alexandru Staicu, Angelica Voinoiu, Eleonóra Fabiánová, Roman Nedela, Jana Oravec Bérešová, Lenka Palcová, Ihab Mansour, Catalina Ciocan, Andrea Franceschi, Francesca Larese Filon, Luca Cegolon, and
    Journal of Epidemiology and Global Health, 2023
    Background SARS-CoV-2 breakthrough infections (BI) after vaccine booster dose are a relevant public health issue. Methods Multicentric longitudinal cohort study within the ORCHESTRA project, involving 63,516 health workers (HW) from 14 European settings. The study investigated the cumulative incidence of SARS-CoV-2 BI after booster dose and its correlation with age, sex, job title, previous infection, and time since third dose. Results 13,093 (20.6%) BI were observed. The cumulative incidence of BI was higher in women and in HW aged < 50 years, but nearly halved after 60 years. Nurses experienced the highest BI incidence, and administrative staff experienced the lowest. The BI incidence was higher in immunosuppressed HW (28.6%) vs others (24.9%). When controlling for gender, age, job title and infection before booster, heterologous vaccination reduced BI incidence with respect to the BNT162b2 mRNA vaccine [Odds Ratio (OR) 0.69, 95% CI 0.63–0.76]. Previous infection protected against asymptomatic infection [Relative Risk Ratio (RRR) of recent infection vs no infection 0.53, 95% CI 0.23–1.20] and even more against symptomatic infections [RRR 0.11, 95% CI 0.05–0.25]. Symptomatic infections increased from 70.5% in HW receiving the booster dose since < 64 days to 86.2% when time elapsed was > 130 days. Conclusions The risk of BI after booster is significantly reduced by previous infection, heterologous vaccination, and older ages. Immunosuppression is relevant for increased BI incidence. Time elapsed from booster affects BI severity, confirming the public health usefulness of booster. Further research should focus on BI trend after 4th dose and its relationship with time variables across the epidemics.
  • SARS-CoV-2 Breakthrough Infections: Incidence and Risk Factors in a Large European Multicentric Cohort of Health Workers
    Stefano Porru, Maria Grazia Lourdes Monaco, Gianluca Spiteri, Angela Carta, Maria Diletta Pezzani, Giuseppe Lippi, Davide Gibellini, Evelina Tacconelli, Ilaria Dalla Vecchia, Emma Sala, Emanuele Sansone, Giuseppe De Palma, Carlo Bonfanti, Massimo Lombardo, Luigina Terlenghi, Enrico Pira, Ihab Mansour, Maurizio Coggiola, Catalina Ciocan, Alessandro Godono, Adonina Tardon, Marta-Maria Rodriguez-Suarez, Guillermo Fernandez-Tardon, Francisco-Jose Jimeno-Demuth, Rafael-Vicente Castro-Delgado, Tania Iglesias Cabo, Maria Luisa Scapellato, Filippo Liviero, Angelo Moretto, Paola Mason, Sofia Pavanello, Anna Volpin, Luigi Vimercati, Silvio Tafuri, Luigi De Maria, Stefania Sponselli, Pasquale Stefanizzi, Antonio Caputi, Fabriziomaria Gobba, Alberto Modenese, Loretta Casolari, Denise Garavini, Cristiana D’Elia, Stefania Mariani, Francesca Larese Filon, Luca Cegolon, Corrado Negro, Federico Ronchese, Francesca Rui, Paola De Michieli, Nicola Murgia, Marco Dell’Omo, Giacomo Muzi, Tiziana Fiordi, Angela Gambelunghe, Ilenia Folletti, Dana Mates, Violeta Claudia Calota, Andra Neamtu, Ovidiu Perseca, Catalin Alexandru Staicu, Angelica Voinoiu, Eleonóra Fabiánová, Jana Bérešová, Zora Kľocová Adamčáková, Roman Nedela, Anna Lesňáková, Jana Holčíková, Paolo Boffetta, Mahsa Abedini, Giorgia Ditano, Shuffield Seyram Asafo, Giovanni Visci, Francesco Saverio Violante, Carlotta Zunarelli, Giuseppe Verlato
    Vaccines, 2022
    Background: The research aimed to investigate the incidence of SARS-CoV-2 breakthrough infections and their determinants in a large European cohort of more than 60,000 health workers. Methods: A multicentric retrospective cohort study, involving 12 European centers, was carried out within the ORCHESTRA project, collecting data up to 18 November 2021 on fully vaccinated health workers. The cumulative incidence of SARS-CoV-2 breakthrough infections was investigated with its association with occupational and social–demographic characteristics (age, sex, job title, previous SARS-CoV-2 infection, antibody titer levels, and time from the vaccination course completion). Results: Among 64,172 health workers from 12 European health centers, 797 breakthrough infections were observed (cumulative incidence of 1.2%). The primary analysis using individual data on 8 out of 12 centers showed that age and previous infection significantly modified breakthrough infection rates. In the meta-analysis of aggregated data from all centers, previous SARS-CoV-2 infection and the standardized antibody titer were inversely related to the risk of breakthrough infection (p = 0.008 and p = 0.007, respectively). Conclusion: The inverse correlation of antibody titer with the risk of breakthrough infection supports the evidence that vaccination plays a primary role in infection prevention, especially in health workers. Cellular immunity, previous clinical conditions, and vaccination timing should be further investigated.
  • Chronic use of Datura stramonium cigarettes and late diagnosis of bullous emphysema in a smoker of marijuana and tobacco
    Angela Gambelunghe, Bruno Aloisio, Cristiana Gambelunghe, Ilenia Folletti, Marino Chiodi, Giacomo Muzi, Nicola Murgia, Marco dell’Omo
    Respiratory Medicine Case Reports, 2022
  • Mild/Moderate Asthma Network in Italy (MANI): a long-term observational study
    Fulvio Braido, Francesco Blasi, Giorgio Walter Canonica, Pierluigi Paggiaro, Bianca Beghè, Matteo Bonini, Giovanna Elisiana Carpagnano, Stefano Del Giacco, Federico Lavorini, Manlio Milanese, Vincenzo Patella, Pierachille Santus, Marco Contoli, , Chiara Allegrini, Ilaria Baiardini, Laura Bonzano, Maria Filomena Caiaffa, Paolo Castelnuovo, Angelo Guido Corsico, Lorenzo Cosmi, Maria Teresa Costantino, Marcello Cottini, Nunzio Crimi, Maria Angiola Crivellaro, Simona D’Alò, Ilenia Folletti, Dario Fornari, Maria Pia Foschino-Barbaro, Laura Franceschini, Domenico Gargano, Kim Lokar Oliani, Mauro Maniscalco, Laura Melissari, Marcello Montagni, Paolo Montuschi, Nicola Murgia, Alessandro Pannofino, Alberto Papi, Roberta Parente, Girolamo Pelaia, Laura Pini, Francesca Puggioni, Nolita Pulerà, Onofrio Resta, Luisa Ricciardi, Erminia Ridolo, Eleonora Savi, Francesca Savoia, Guglielmo Scala, Gianenrico Senna, Salvatore Tripodi, Alessandro Vatrella, Maria Teresa Ventura, Vittorio Maria Viviano, Mona-Rita Yacoub
    Journal of Asthma, 2022
  • Impact of the covid-19 pandemic and work-related stress in umbrian healthcare workers during phase 1 in Italy
    Medicina Del Lavoro, 2021
  • Mepolizumab Effectiveness and Allergic Status in Real Life
    Bruno Sposato, Marco Scalese, Gianna Camiciottoli, Giovanna Elisiana Carpagnano, Corrado Pelaia, Pierachille Santus, Mauro Maniscalco, Angelo Corsico, Amelia Grosso, Stefano Baglioni, Nicola Murgia, Ilenia Folletti, Girolamo Pelaia, Simonetta Masieri, Carlo Cavaliere, Antonino Musarra, Elena Bargagli, Alberto Ricci, Manuela Latorre, Pierluigi Paggiaro, Paola Rogliani
    International Archives of Allergy and Immunology, 2021
  • Exposure to additives or multigrain flour is associated with high risk of work-related allergic symptoms among bakers
    Mario Olivieri, Nicola Murgia, Gianluca Spiteri, Carlo Alberto Biscardo, Pierpaolo Marchetti, Ilenia Folletti, Giuseppe Verlato
    Occupational and Environmental Medicine, 2021
  • Persistence of both reversible airway obstruction and higher blood eosinophils may predict lung function decline in severe asthma
    Bruno Sposato, Marco Scalese, Alberto Ricci, Paola Rogliani, Pierluigi Paggiaro, B. Sposato, M. G. Migliorini, M. Di Tomassi, C. Olivieri, A. Perrella, G. Camiciottoli, R. Maselli, G. Pelaia, M. T. Busceti, E. Sabato, M. G. Cagnazzo, F. Colombo, L. Palumbo, A. Ravazzi, C. Bucca, M. F. Caiaffa, A. Berra, C. Calabrese, A. A. Stanziola, P. Schino, M. Di Gioacchino, P. Rogliani, M. Cazzola, A. Segreti, E. A. Pastorello, G. Scibilia, A. Vianello, M. R. Marchi, L. Paladini, S. Baglioni, M. Abbritti, F. Almerigogna, A. Matucci, A. Vultaggio, E. Maggi, P. Maestrelli, G. Guarnieri, G. Steinhilber, M Bonavia, P. Rottoli, E. Bargagli, G. Senna, M. Caminati, L. Macchia, V. Bellia, N. Scichilone, P. Paggiaro, F. Novelli, M. Latorre, L. Vergura, S. Masieri, M. Scalese, Y. Rosati, M. Milanese, I. Folletti, R. Pio, A. Pio, U. Maccari, C. Maggiorelli, R. Scala, L. Vignale, N. Pulerà, G. E. Carpagnano, M. P. Foschino Barbaro, and
    Clinical Respiratory Journal, 2021
  • Real-life Mepolizumab effectiveness in severe eosinophilic asthmatics with nasal polyposis
    B. Sposato, M. Scalese, G. Camiciottoli, G.E. Carpagnano, C. Pelaia, P. Santus, M. Maniscalco, A. Corsico, A. Grosso, S. Baglioni, N. Murgia, I. Folletti, G. Pelaia, S. Masieri, C. Cavaliere, A. Musarra, E. Bargagli, A. Ricci, M. Latorre, P. Rogliani, P. Paggiaro
    Respiratory Medicine and Research, 2020
  • Respiratory diseases and allergy in farmers working with livestock: a EAACI position paper
    T. Sigsgaard, I. Basinas, G. Doekes, F. de Blay, I. Folletti, D. Heederik, A. Lipinska-Ojrzanowska, D. Nowak, M. Olivieri, S. Quirce, M. Raulf, J. Sastre, V. Schlünssen, J. Walusiak-Skorupa, A. Siracusa
    Clinical and Translational Allergy, 2020
  • Industrial air pollution and respiratory health status among residents in an industrial area in central Italy
    Giulia Paolocci, Lisa Bauleo, Ilenia Folletti, Nicola Murgia, Giacomo Muzi, Carla Ancona
    International Journal of Environmental Research and Public Health, 2020
  • Mepolizumab effectiveness on small airway obstruction, corticosteroid sparing and maintenance therapy step-down in real life
    Bruno Sposato, Gianna Camiciottoli, Elena Bacci, Marco Scalese, Giovanna Elisiana Carpagnano, Corrado Pelaia, Pierachille Santus, Mauro Maniscalco, Simonetta Masieri, Angelo Corsico, Nicola Scichilone, Stefano Baglioni, Nicola Murgia, Ilenia Folletti, Giulio Bardi, Amelia Grosso, Paolo Cameli, Manuela Latorre, Antonino Musarra, Elena Bargagli, Alberto Ricci, Girolamo Pelaia, Pierluigi Paggiaro, Paola Rogliani
    Pulmonary Pharmacology and Therapeutics, 2020
  • Food processing and occupational respiratory allergy- An EAACI position paper
    Mohamed F. Jeebhay, Gianna Moscato, Berit E. Bang, Ilenia Folletti, Agnieszka Lipińska‐Ojrzanowska, Andreas L. Lopata, Gianni Pala, Santiago Quirce, Monika Raulf, Joaquin Sastre, Ines Swoboda, Jolanta Walusiak‐Skorupa, Andrea Siracusa
    Allergy European Journal of Allergy and Clinical Immunology, 2019
  • Severe Occupational Asthma: Insights From a Multicenter European Cohort
    Olivier Vandenplas, Julien Godet, Laura Hurdubaea, Catherine Rifflart, Hille Suojalehto, Jolanta Walusiak-Skorupa, Xavier Munoz, Joaquin Sastre, Pavlina Klusackova, Vicky Moore, Rolf Merget, Donatella Talini, Jorunn Kirkeleit, Paola Mason, Ilenia Folletti, Paul Cullinan, Gianna Moscato, Santiago Quirce, Jennifer Hoyle, David Sherson, Paula Kauppi, Alexandra Preisser, Nicolas Meyer, Frédéric de Blay, Olivier Vandenplas, Catherine Rifflart, Pavlina Klusackova, David Sherson, Hille Suojalehto, Pirjo Hölttä, Paula Kauppi, Frédéric de Blay, Laura Hurdubaea, Rolf Merget, Alexandra M. Preisser, Volker Harth, Piero Maestrelli, Paola Mason, Gianna Moscato, Patrizia Pignatti, Pierluigi Paggiaro, Donatella Talini, Marco dell’Omo, Ilenia Foletti, Cecilie Svanes, Jorunn Kirkeleit, Jolanta Walusiak-Skorupa, Marta Wiszniewska, Xavier Munoz, Christian Romero-Mesones, Joaquin Sastre, Mar Fernandez-Nieto, Santiago Quirce, Marta Sanchez-Jareno, Paul Cullinan, Julie Cannon, Sherwood Burge, Vicky Moore, Jennifer Hoyle
    Journal of Allergy and Clinical Immunology in Practice, 2019
  • Higher blood eosinophil levels after omalizumab treatment may be associated with poorer asthma outcomes
    Bruno Sposato, Marco Scalese, Manlio Milanese, Simonetta Masieri, Carlo Cavaliere, Manuela Latorre, Nicola Scichilone, Alberto Ricci, Alberto Cresti, Pierachille Santus, Carmela Olivieri, Antonio Perrella, Paola Rogliani, Pierluigi Paggiaro, B. Sposato, M.G. Migliorini, M. Di Tomassi, C. Olivieri, A. Perrella, G. Camiciottoli, R. Maselli, G. Pelaia, M.T. Busceti, E. Sabato, M.G. Cagnazzo, F. Colombo, L. Palumbo, A. Ravazzi, C. Bucca, M.F. Caiaffa, A. Berra, C. Calabrese, A.A. Stanziola, P. Schino, M. Di Gioacchino, P. Rogliani, M. Cazzola, A. Segreti, E.A. Pastorello, G. Scibilia, A. Vianello, M.R. Marchi, L. Paladini, S. Baglioni, M. Abbritti, F. Almerigogna, A. Matucci, A. Vultaggio, E. Maggi, P. Maestrelli, G. Guarnieri, G. Steinhilber, M. Bonavia, P. Rottoli, E. Bargagli, G. Senna, M. Caminati, L. Macchia, V. Bellia, N. Scichilone, P. Paggiaro, F. Novelli, M. Latorre, L. Vergura, S. Masieri, M. Scalese, Y. Rosati, M. Milanese, I. Folletti, R. Pio, A. Pio, U. Maccari, C. Maggiorelli, R. Scala, L. Vignale, N. Pulerà, G.E. Carpagnano, M.P. Foschino Barbaro
    Journal of Allergy and Clinical Immunology in Practice, 2019
  • Medico-legal implications of mobbing: A case law
    Rivista Di Psichiatria, 2018
  • Occupational risk factors for idiopathic pulmonary fibrosis in Southern Europe: A case-control study
    Giulia Paolocci, Ilenia Folletti, Kjell Torén, Magnus Ekström, Marco Dell’Omo, Giacomo Muzi, Nicola Murgia
    BMC Pulmonary Medicine, 2018
  • Allergic sensitization to common pets (cats/dogs) according to different possible modalities of exposure: An Italian Multicenter Study
    , G. Liccardi, L. Calzetta, G. Baldi, A. Berra, L. Billeri, M. Caminati, P. Capano, E. Carpentieri, A. Ciccarelli, M. A. Crivellaro, M. Cutajar, M. D’Amato, I. Folletti, F. Gani, D. Gargano, D. Giannattasio, M. Giovannini, C. Lombardi, M. Lo Schiavo, F. Madonna, M. Maniscalco, A. Meriggi, C. Micucci, M. Milanese, C. Montera, G. Paolocci, R. Parente, A. Pedicini, R. Pio, F. Puggioni, M. Russo, A. Salzillo, P. Scavalli, N. Scichilone, B. Sposato, A. Stanziola, G. Steinhilber, A. Vatrella, P. Rogliani, G. Passalacqua
    Clinical and Molecular Allergy, 2018
  • United Airway Disease in Occupational Allergy
    Ilenia Folletti, G. Paolocci, G. Muzi, A. Siracusa
    Current Treatment Options in Allergy, 2017
  • Update on asthma and cleaning agents
    Ilenia Folletti, Andrea Siracusa, Giulia Paolocci
    Current Opinion in Allergy and Clinical Immunology, 2017
  • Occupational Medicine, Respiratory Diseases, Occupational And Environmental Toxicology, University of Perugia: main activities
    M. Dell'Omo, I. Folletti, Angela Gambelunghe, N. Murgia, Giulia Paolocci, G. Muzi
    Medicina Del Lavoro, 2017
  • Skin prick testing in the diagnosis of occupational type i allergies-a EAACI position paper
    V. van Kampen, F. de Blay, I. Folletti, P. Kobierski, G. Moscato, M. Olivieri, S. Quirce, J. Sastre, J. Walusiak-Skorupa, M. Raulf
    Allergologie, 2017
  • Effects of omalizumab in severe asthmatics across ages: A real life Italian experience
    B. Sposato, M. Scalese, M. Latorre, N. Scichilone, A. Matucci, M. Milanese, S. Masieri, G. Rolla, G. Steinhilber, Y. Rosati, A. Vultaggio, I. Folletti, S. Baglioni, E. Bargagli, M. Di Tomassi, R. Pio, A. Pio, U. Maccari, C. Maggiorelli, M.G. Migliorini, L. Vignale, N. Pulerà, G.E. Carpagnano, M.P. Foschino Barbaro, A. Perrella, P.L. Paggiaro
    Respiratory Medicine, 2016
  • Upper airway and eye involvement in polyurethane shoe sole production workers
    Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia, 2016
  • Occupational rhinitis affects occupational asthma severity
    Gianna Moscato, Gianni Pala, Ilenia Folletti, Andrea Siracusa, Santiago Quirce
    Journal of Occupational Health, 2016
  • Non respiratory symptoms in asthma as possible predictors of exacerbations
    Gennaro Liccardi, Gennaro Baldi, Adriano Berra, Emanuela Carpentieri, Marina Cutajar, Maria D'Amato, Mario Del Donno, Bruno Del Prato, Ilenia Folletti, Federica Gani, Domenico Gargano, Domenico Giannattasio, Michele Giovannini, Antonio Infantino, Carlo Lombardi, Mario Lo Schiavo, Francesco Madonna, Mauro Maniscalco, Antonio Meriggi, Manlio Milanese, Carmen Montera, Antonio Pio, Maria Russo, Antonello Salzillo, Patrizia Scavalli, Nicola Scichilone, Bruno Sposato, Anna Stanziola, Antonio Starace, Alessandro Vatrella, Gennaro D'Amato, Giovanni Passalacqua
    Journal of Allergy and Clinical Immunology in Practice, 2015
  • Deviation from intention to treat analysis in randomised trials and treatment effect estimates: Meta-epidemiological study
    I. Abraha, A. Cherubini, F. Cozzolino, R. De Florio, M. L. Luchetta, J. M. Rimland, I. Folletti, M. Marchesi, A. Germani, M. Orso, P. Eusebi, A. Montedori
    BMJ Online, 2015
  • Occupational anaphylaxis - An EAACI task force consensus statement
    A. Siracusa, I. Folletti, R. Gerth van Wijk, M. F. Jeebhay, G. Moscato, S. Quirce, M. Raulf, F. Ruëff, J. Walusiak-Skorupa, P. Whitaker, S. M. Tarlo
    Allergy European Journal of Allergy and Clinical Immunology, 2015
  • Regular versus as-needed budesonide and formoterol combination treatment for moderate asthma: A non-inferiority, randomised, double-blind clinical trial
    Alberto Papi, Brunilda Marku, Nicola Scichilone, Piero Maestrelli, Pierluigi Paggiaro, Marina Saetta, Stefano Nava, Ilenia Folletti, Giuseppina Bertorelli, Stefano Bertacco, Marco Contoli, Mario Plebani, Maria Pia Foschino Barbaro, Antonio Spanevello, Maria Aliani, Marco Pannacci, Paolo Morelli, Bianca Beghé, Leonardo M Fabbri
    Lancet Respiratory Medicine, 2015
  • A survey of clinical features of allergic rhinitis in adults
    Cristoforo Incorvaia
    Medical Science Monitor, 2014
  • EAACI position paper on assessment of cough in the workplace
    G. Moscato, G. Pala, P. Cullinan, I. Folletti, R. Gerth van Wijk, P. Pignatti, S. Quirce, J. Sastre, E. Toskala, O. Vandenplas, J. Walusiak-Skorupa, J. L. Malo
    Allergy European Journal of Allergy and Clinical Immunology, 2014
  • Asthma and rhinitis in cleaning workers: A systematic review of epidemiological studies
    Ilenia Folletti, Jan-Paul Zock, Gianna Moscato, Andrea Siracusa
    Journal of Asthma, 2014
  • Hymenoptera venom allergy: Work disability and occupational impact of venom immunotherapy
    Giulia Paolocci, Ilenia Folletti, Kjell Torén, Giacomo Muzi, Nicola Murgia
    BMJ Open, 2014
  • Cypress pollen: An unexpected major sensitizing agent in different regions of Italy
    Journal of Investigational Allergology and Clinical Immunology, 2014
  • Asthma and exposure to cleaning products - A European Academy of Allergy and Clinical Immunology task force consensus statement
    A. Siracusa, F. De Blay, I. Folletti, G. Moscato, M. Olivieri, S. Quirce, M. Raulf-Heimsoth, J. Sastre, S. M. Tarlo, J. Walusiak-Skorupa, J.-P. Zock
    Allergy European Journal of Allergy and Clinical Immunology, 2013
  • EAACI position paper: Skin prick testing in the diagnosis of occupational type i allergies
    V. van Kampen, F. de Blay, I. Folletti, P. Kobierski, G. Moscato, M. Olivieri, S. Quirce, J. Sastre, J. Walusiak‐Skorupa, M. Raulf‐Heimsoth
    Allergy European Journal of Allergy and Clinical Immunology, 2013
  • Evaluation of commercial skin prick test solutions for selected occupational allergens
    V. van Kampen, F. de Blay, I. Folletti, P. Kobierski, G. Moscato, M. Olivieri, S. Quirce, J. Sastre, J. Walusiak‐Skorupa, N. Kotschy‐Lang, H. Müsken, V. Mahler, S. Schliemann, U. Ochmann, J. Sültz, M. Worm, I. Sander, E. Zahradnik, T. Brüning, R. Merget, M. Raulf‐Heimsoth
    Allergy European Journal of Allergy and Clinical Immunology, 2013
  • Non-IgE-mediated and irritant-induced work-related rhinitis
    Andrea Siracusa, Ilenia Folletti, Gianna Moscato
    Current Opinion in Allergy and Clinical Immunology, 2013
  • Epidemiological evidence of possible mucoskeletal, cardiovascvlar and neoplastic effects in professional drivers
    Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia, 2012
  • Reduction of tobacco smoking habit among physicians in a general hospital in Central Italy
    Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia, 2012
  • EAACI consensus statement for investigation of work-related asthma in non-specialized centres
    G. Moscato, G. Pala, C. Barnig, F. De Blay, S. R. Del Giacco, I. Folletti, E. Heffler, P. Maestrelli, G. Pauli, L. Perfetti, S. Quirce, J. Sastre, A. Siracusa, J. Walusiak‐Skorupa, R. Gerth van Wjik
    Allergy European Journal of Allergy and Clinical Immunology, 2012
  • Rhinitis in work-exacerbated asthma
    European Respiratory Disease, 2012
  • EAACI Position Paper: Prevention of work-related respiratory allergies among pre-apprentices or apprentices and young workers
    G. Moscato, G. Pala, M. A. Boillat, I. Folletti, R. Gerth van Wijk, D. Olgiati-Des Gouttes, L. Perfetti, S. Quirce, A. Siracusa, J. Walusiak-Skorupa, S. M. Tarlo
    Allergy European Journal of Allergy and Clinical Immunology, 2011
  • Sensitization to horse allergens in Italy: A multicentre study in urban atopic subjects without occupational exposure
    G. Liccardi, G. D’Amato, L. Antonicelli, A. Berra, L. Billeri, G.W. Canonica, G. Casino, L. Cecchi, I. Folletti, F. Gani, C. Lombardi, M. Lo Schiavo, A. Meriggi, M. Milanese, G. Passalacqua, R. Pio, G. Rolla, M. Russo, S. Scaccianoce, G.E. Senna, P. Scavalli, N. Scichilone, B. Sposato, A. Siracusa, M.T. Ventura, Allergy Study Group of the Italian Society of Respiratory Medicine (SIMeR)
    International Archives of Allergy and Immunology, 2011
  • Re: Allergy to rodents: An update
    I. Folletti, A. Siracusa
    Clinical and Experimental Allergy, 2011
  • Occupational asthma
    Italian Journal of Allergy and Clinical Immunology, 2010
  • Basic concepts of occupational allergy for allergology practice
    Italian Journal of Allergy and Clinical Immunology, 2010
  • EAACI position paper on occupational rhinitis
    Gianna Moscato, Olivier Vandenplas, Roy Gerth Van Wijk, Jean-Luc Malo, Luca Perfetti, Santiago Quirce, Jolanta Walusiak, Roberto Castano, Gianni Pala, Denyse Gautrin, Hans De Groot, Ilenia Folletti, Mona Rita Yacoub, Andrea Siracusa
    Respiratory Research, 2009
  • Occupational rhinitis
    EAACI Task Force on Occupational Rhinitis, G. Moscato, O. Vandenplas, R. Gerth Van Wijk, J. L. Malo, S. Quirce, J. Walusiak, R. Castano, H. De Groot, I. Folletti, D. Gautrin, M. R. Yacoub, L. Perfetti, A. Siracusa
    Allergy European Journal of Allergy and Clinical Immunology, 2008
  • Have the prevalence and incidence of occupational asthma and rhinitis because of laboratory animals declined in the last 25 years?
    I. Folletti, A. Forcina, A. Marabini, A. Bussetti, A. Siracusa
    Allergy European Journal of Allergy and Clinical Immunology, 2008
  • Latex allergy in hospital workers - Follow- up of symptomatic subjects
    Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia, 2007
  • Have the prevalence and incidence of occupational asthma and rhinitis due to laboratory animals declined in the last 25 years?
    Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia, 2007
  • Tobacco smoke and involuntary smoking among hospital workers after enforcement of "Legge Sirchia"
    Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia, 2006
  • Smoking and occupational asthma
    A. Siracusa, A. Marabini, I. Folletti, G. Moscato
    Clinical and Experimental Allergy, 2006
  • Prevalence and determinants of low back pain in hospital workers
    Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia, 2005
  • Upper airways impariment in workers employed in the production of polyurethane soles
    Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia, 2004
  • Occupational asthma: The role of airways inflammation and remodelling in persistent respiratory symptoms and bronchial hyper-responsiveness
    Medicina Del Lavoro, 2004
  • Using induced sputum in the follow-up of hypersensitivity pneumonitis
    Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia, 2003