-Dentis : Faculty of Dentistry, Universitas Padjadjaran, Indonesia
-Oral and Maxillofacial Surgeon : Faculty of Dentistry, Universitas Padjadjaran, Indonesia
-Ph.D : Faculty Of Medicine, Universitas Padjadjaran, Indonesia
RESEARCH INTERESTS
-Oral and Maxillofacial Surgery
- Bone and Wound Healing
- Trauma Maxillofacial
- Temporo mandibular joint
- Facial Cleft
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Scopus Publications
Scopus Publications
Management of extracapsular condylar fracture with open reduction internal fixation in children: a case report Puspita Rahardjo Putri, Annisa Hasna Nurzahra Tauziri, Medinanisa Kintara, Endang Sjamsudin, Eka Marwansyah Oli'i Dental Journal, 2026 Background: Mandibular condyle fracture is a fracture of the mandible that quite often occurs due to trauma. Complications that often ensue from condyle fractures in children are ankylosis and temporomandibular joint disorders. Mandibular fracture treatment can involve open reduction or closed reduction. Fracture treatment is simple and appropriate technique can prevent further complications. Purpose: The aim of this case report is to present the management of condylar fractures in pediatric patients resulting from trauma using the open reduction technique. Case: An eight-year-old female patient after experiencing a fall presented with complaints of not being able to open her mouth. Clinical and radiographic examination showed a type IIIb condyle fracture. Case management: The patient was then treated with the open reduction internal fixation (ORIF) technique. Two plates were installed in the patient’s left condylar area using a preauricular approach. The patient showed improved results on the 10th day of control. Conclusion: Treatment of mandibular condyle cases with the ORIF technique in children gives quite good results. Regular evaluation is needed.
Association of Growth Hormone Receptor Gene Polymorphisms (rs6180, rs6182, rs6184) with Skeletal Class III Malocclusion and Prognathic Mandibles in the Deutero-Malay Race Seto Adiantoro Sadputranto, Ani Melani Maskoen, Avi Laviana, Endang Sjamsudin, Arlette S. Setiawan European Journal of Dentistry, 2025 Objective A prognathic mandible, characterized by the anterior protrusion of the mandible, is often associated with skeletal class III malocclusion. Polymorphisms rs6180, rs6182, and rs6184 in the growth hormone receptor (GHR) gene are thought to influence the development of this condition among various races. This study explores the link between these GHR gene polymorphisms and class III skeletal malocclusion in individuals with prognathic mandibles within the Deutero-Malay race. Materials and Methods Saliva samples from 104 participants were analyzed using polymerase chain reaction sequencing. The association between GHR polymorphisms and malocclusion phenotype was examined using the chi-square statistical method. Results Significant differences were observed in the rs6180 AC and CC genotypes between control and outcome groups, with a p-value of 0.023 and an odds ratio of 1.667, suggesting a notable association. Discussion The rs6180 polymorphism in the GHR gene appears to alter protein structure and function, promoting mandibular growth in the anteroposterior direction among the Deutero-Malay race. Conclusion The rs6180 polymorphism in the GHR gene is significantly associated with the occurrence of skeletal class III malocclusion accompanied by prognathic mandibles in the Deutero-Malay race.
The Role of IR Technology (Immersive Reality) Tooth Extraction Simulators for Dental Education (Scoping Review) Journal of International Dental and Medical Research, 2025
The Role of Inflammatory Biomarkers (IL-1, IL-6, TNF-α, and Alpha-Amylase) in Saliva on Post-Odontectomy Swelling: A Rapid Review Fauzah Iramawati Saim, Endang Sjamsudin, Nuroh Najmi Journal of Inflammation Research, 2025 Background: Odontectomy is a commonly performed surgical procedure in the oral cavity and has several possible postoperative complications, including swelling. In addition to clinical examination, post-odontectomy swelling can be identified by utilizing saliva samples to analyze inflammatory biomarkers. The purpose of this study was to determine the role of inflammatory biomarkers IL-1, IL-6, TNF-α, and alpha-amylase in saliva on post-odontectomy swelling. Methods: A rapid literature review of clinical studies was conducted using the PRISMA framework. Article searches were performed on six databases (PubMed, ScienceDirect, SpringerLink, Cochrane Library, and EBSCOhost) using boolean operators and hand searching on Google Scholar. Results: Ten articles met the inclusion criteria. A risk of bias assessment was conducted using the JBI critical appraisal tools. Seven articles analyzed alpha-amylase, two articles analyzed TNF-α, and one article analyzed IL-1, IL-6, and TNF-α simultaneously to see the swelling or inflammation that occurs post-odontectomy. These four biomarkers were examined before, immediately after, or up to several days after the procedure. Significant elevations in biomarkers including IL-1, IL-6, TNF-a, and alpha-amylase are seen in the majority of articles. Post-procedure alpha-amylase elevation was observed along with swelling, pain, and fear associated with the odontectomy procedure. Increases in IL-1, IL-6, and TNF-α were observed due to tissue manipulation during the procedure that initiated the production of these proinflammatory cytokines. Conclusion: Inflammatory biomarkers IL-1, IL-6, TNF-α, and alpha-amylase in saliva play a role in post-odontectomy swelling, as their levels increase the intensity of swelling or inflammation also tends to rise. These biomarkers contribute to swelling through mechanisms involving immune cell recruitment, increased vascular permeability, and acute responses to pain and stress. Although it is constrained by the lack of relevant research, this review provides recommendations for further research into the most pertinent salivary biomarkers for identifying post-odontectomy swelling.
Immersive Reality–Based Training Simulator for Dental Extraction: Protocol for a Randomized Pilot Trial Endang Sjamsudin, Muhammad Ruslin, Olivia Avriyanti Hanafiah, Carolina Stevanie, Sri Hastuti Kurniawan, Muh Anshar, Paolo Boffano, Tymour Forouzanfar, Cortino Sukotjo Jmir Research Protocols, 2025 Background Dental students’ competencies are shaped by their training, yet traditional methods with mannequins often lack the depth necessary for comprehensive understanding, potentially impacting clinical proficiency. Immersive reality (IR) innovatively offers interactive and scenario-based environments that may enhance skill acquisition. Objective This study evaluates the effectiveness of IR-based training implementation in comparison with conventional training methods for dental extractions. Methods A prospective multicenter randomized clinical trial was conducted. Students were randomized to either IR-based training on open and closed extractions or conventional hands-on tutorials by oral surgeons. Post training, participants’ satisfaction and understanding were assessed and analyzed. Results As of September 2025, 60 students from Hasanuddin University, Makassar, and Padjajaran University, Bandung, have been enrolled, and study enrollment will be expanded to Universitas Sumatera Utara, Medan. Data collection is ongoing and will conclude in November 2025, with expected dissemination in early 2026. Conclusions IR-based training offers a novel approach that may boost motivation, knowledge retention, and skill transfer in dental education. This pilot protocol explores IR’s feasibility and potential to advance dental students’ competencies. Trial Registration Indonesian Clinical Research Registry INA-QES4CC5; https://ina-crr.kemkes.go.id/en/studi/207 International Registered Report Identifier (IRRID) DERR1-10.2196/74978
Variability in Positions and Factors Contributing to Surgical Difficulty of Impacted Third Molars Endang Sjamsudin, Anggun Rafisa, Nuroh Najmi European Journal of Dentistry, 2024 Objectives This study aimed to provide valuable insights into the variability of third molar positions and factors influencing their surgical time and technique. Materials and Methods This cross-sectional study included a total of 48 eligible participants, aged 18 to 45 years, diagnosed with impacted teeth, and who had undergone surgery. Exclusion criteria comprised the absence of the second molar, the presence of systemic diseases, a history of radiation therapy, and pregnancy or lactation. Participants completed a questionnaire covering demographic data, physical metrics, and information on systemic conditions and disorders. Preoperative assessments included vital sign measurements. Panoramic imaging was employed to evaluate the third molar distance to the occlusal plane, degrees of angulation, eruption space, and distance to the alveolar inferior canal. Surgical difficulty in this study was measured by two outcomes: surgical time and technique. Statistical Analysis To assess differences in impacted third molar positions among groups, Independent samples t-test and One-way analysis of variance were used for normally distributed data without outliers; otherwise, the Mann–Whitney U test and Kruskal–Wallis H test were utilized. The Spearman's rank correlation was utilized to explore relationships between vital signs, impacted third molar positions, surgical time, and surgical technique. Results There were no significant differences in third molar positions between age and body mass index groups. Significant differences in distance to the occlusal plane were observed between third molars in quadrants 2 and 3 (p = 0.002) and quadrants 2 and 4 (p = 0.005). A significant difference in eruption space was found between sexes (p = 0.016). A significant negative correlation was discovered between surgical time and respiration rate per minute (p = 0.028). Conclusion This study found that males have greater third molar eruption space than females, and maxillary third molars have a greater distance to the occlusal plane compared with mandibular third molars. The importance of vital signs as contributing factors to surgical difficulty is highlighted, emphasizing their relevance in clinical practice.
Scoping review of outcome measures in cleft care used in research and reports Erli Sarilita, Endang Sjamsudin, Peter A. Mossey Orthodontics and Craniofacial Research, 2024 Treatment outcome measures are critical in the decision making of best practices in the OFC field. OFC consortium working groups provided standardization of outcome measures based on previous treatment outcome studies. However, the implementation of such standardization in OFC centres worldwide is unknown. This study presented mapped outcome measures in cleft care using a structured review method complemented by quantitative overview of the relevant published research to provide initial guidelines for the implementation of treatment outcome standardization. A scoping review of the literature of treatment outcomes in cleft care following Preferred Reporting Items for Systematic reviews and Meta‐Analyses extension for Scoping Reviews guidelines was performed. The selected indexed paper in outcome measures mapped following the international consortium in standard set of outcome measures in cleft care. Three hundred and sixty‐five articles were filtered. The most discussed domains of cleft care were dental and oral health, appearance and speech/communication. Overall, the majority of publications were produced in high‐income countries. The current review indicates that there are inequalities of treatment outcome studies among the domain of cleft care. In addition, there are also inequalities of published articles from HIC versus LMIC in treatment outcomes. This information can be used to develop targeted interventions aimed at encouraging cleft centres worldwide to adapt standardized outcome measures.
Immunoexpression Rate of Human Telomerase Reverse Transcriptase in Rapidly Involuting Congenital Hemangioma Patients Journal of International Dental and Medical Research, 2023
Activity of Ethanol Extract of Centella asiatica (Linn.) Urban in Inhibiting the Progression of Buccal Mucosal Dysplasia Lesions in Wistar Rats Journal of International Dental and Medical Research, 2023
A Preliminary Study on Clinical Profiles of Non-Syndromic Cleft Lip with or without Cleft Palate During Community Services in Indonesia 2020-2022 Journal of International Dental and Medical Research, 2023
Facial Pain Evaluation on Post-Orthognathic Surgery Patients: A Scoping Review Journal of International Dental and Medical Research, 2023
Deuteromelayu Race Characteristic on Class III Malocclusion with Mandibular Prognathism Journal of International Dental and Medical Research, 2023
Wound healing activity of binahong (Anredera cordifolia (Ten.) Steenis) leaves extract towards NIH-3T3 fibroblast cells Journal of International Dental and Medical Research, 2019
