EMRAH UGUZ

@aybu.edu.tr

Associate Professor of Cardiovascular Surgery, Faculty of Medicine
Ankara Yildirim Beyazit University

RESEARCH, TEACHING, or OTHER INTERESTS

Medicine, Surgery, Tourism, Leisure and Hospitality Management
55

Scopus Publications

451

Scholar Citations

10

Scholar h-index

10

Scholar i10-index

Scopus Publications

  • De Ritis Ratio as an Independent Predictor of In-Hospital Mortality in Surgically Treated Acute Aortic Dissection
    Kemal Eşref Erdoğan, Burak Kardeşler, Muhammet Fethi Sağlam, Emrah Uğuz, Murat Yücel, Servet Turgut, Mehmet Murat Yiğitbaşı, Mehmet Erdoğan, Kamuran Kalkan, Erol Şener
    Journal of Clinical Medicine, 2026
    Background/Objectives: Every hour of delay in treating acute aortic dissection (AAD) increases mortality by 1–2%, underscoring the critical need for rapid identification of high-risk patients. Despite advances in surgical management, in-hospital mortality remains substantial, and early, reliable risk stratification tools are urgently needed. We targeted to assess the relationship between the De Ritis ratio (DRr) and in-hospital mortality in patients experiencing surgery for AAD. Methods: In this single-center retrospective study, 182 patients who underwent surgery for AAD between 2020 and 2025 were included. Demographic, clinical, laboratory, and echocardiographic data were analyzed. Receiver operating characteristic analysis was used to estimate the DRr’s discriminatory ability, and univariable and multivariable logistic regression analyses were utilized to find predictors of in-hospital mortality. Results: In-hospital mortality occurred in 59 patients (32.4%). When comparing survivors to non-survivors, the DRr was noticeably greater. Along with age, lactate level, and ejection fraction, the DRr continued to be an independent predictor of in-hospital mortality in multivariable analysis. Receiver operating characteristic analysis showed moderate discriminatory performance of the DRr, with an area under the curve of 0.701 and an optimal cut-off value of 1.308. Conclusions: The DRr is a practical and accessible biomarker related to in-hospital mortality in surgically treated AAD and may provide incremental prognostic value when used alongside established clinical and laboratory parameters.
  • Clinical utility of hematological inflammatory indices in predicting pulmonary embolism in patients with lower extremity deep vein thrombosis
    Murat Yucel, Hakan Comakli, Gokay Deniz, Muhammet Fethi Saglam, Kemal Esref Erdogan, Emrah Uguz, Bahadir Benli
    Turkish Journal of Vascular Surgery, 2026
    Aim: Despite advances in diagnostic strategies, easily accessible biomarkers that can reliably predict pulmonary embolism (PE) in patients with deep vein thrombosis (DVT) are lacking. Recently, systemic inflammatory indices, such as the systemic immune-inflammation index (SII), systemic inflammatory response index (SIRI), and aggregate index of systemic inflammation (AISI), have been investigated as potential prognostic tools. This study aimed to evaluate the predictive value and clinical applicability of these markers in identifying PE in patients with lower extremity DVT. Material and Methods: A retrospective propensity score–matched cohort study was conducted in patients diagnosed with acute proximal lower extremity DVT. Two groups were compared: patients with isolated DVT and those with concurrent DVT and PE were compared. Propensity score matching yielded 290 patients in each group. Novel systemic inflammatory indices derived from hematological parameters (SII, SIRI, and AISI) were evaluated together with neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and traditional biomarkers (C-reactive protein (CRP) and D-dimer). Comparative analyses, logistic regression, and receiver operating characteristic (ROC) curve assessments were performed. Results: Inflammatory indices (NLR, PLR, SII, and SIRI) and conventional biomarkers (CRP and D-dimer) were higher in the DVT and PE group compared to the isolated DVT group (all p<0.001). Multivariate analysis identified NLR, CRP, and D-dimer as independent predictors of PE. Receiver operating characteristic (ROC) analysis demonstrated the strongest diagnostic accuracy for CRP (AUC 0.811), followed by D-dimer (AUC 0.746) and NLR (AUC 0.735) levels. Conclusion: Easily measurable and low-cost biomarkers, particularly NLR, along with CRP and Ddimer, provide significant predictive value for PE in patients with DVT. These parameters may support early risk stratification and assist in clinical decision-making when advanced imaging is not readily available.
  • Diabetic Peripheral Arterial Disease Versus Thromboangiitis Obliterans: A Multidimensional Comparison of Clinical Phenotype, Biomarkers, and Outcomes
    Murat Yücel, Hakan Çomaklı, Muhammet Fethi Sağlam, Kemal Eşref Erdoğan, Nur Gizem Elipek, Ömer Abdullah Yavuz, Emrah Uğuz
    Diagnostics, 2026
    Objective: This study aimed to compare thromboangiitis obliterans (TAO) and diabetic peripheral vascular disease (DPVD), the two major causes of distal limb ischemia, within a single analytical framework. The comparison was not limited to practical biomarkers that could support differential diagnosis but was based on multidimensional parameters that determine the clinical spectrum and prognosis. The two cohorts were systematically evaluated in terms of demographics and comorbidity burden, clinical presentation and limb involvement pattern, ulcer prevalence and localization, real-life treatment strategies (medical, endovascular, and surgical), and hard clinical endpoints (major/minor amputation, hospitalization, and all-cause mortality). DPVD was phenotyped according to the lesion level as isolated distal, isolated proximal, or multilevel. Within this framework, the isolated distal diabetic peripheral vascular disease (d-DPVD) subgroup was analyzed to determine how it differs from TAO in terms of clinical course, treatment patterns, and outcomes, despite the distal anatomical similarity. Methods: In this single-center retrospective cohort study, conducted between June 2019 and June 2025, 120 non-diabetic patients who met the angiographic TAO criteria were compared with 395 patients with DPVD with infrapopliteal/pedal atherosclerotic involvement. Clinical characteristics, ulcer topography, treatment strategies, and outcomes were recorded. The discriminatory value of the blood count and lipid-based inflammatory/atherogenic indices were evaluated using logistic regression and receiver operating characteristic (ROC) curve analyses. Additionally, a separate subgroup analysis was performed for the d-DPVD subgroup, which was considered the closest to the TAO phenotype in this study design. Results: Patients with DPVD were significantly older than those with TAO (61.1 ± 12.1 vs. 39.7 ± 7.9 years; p < 0.001), and male predominance was more pronounced in the TAO group (94.2% vs. 84.8%). Compared with TAO, DPVD was associated with a higher cardiometabolic comorbidity burden and increased inflammatory and atherogenic indices. Although the overall ulcer prevalence was comparable, DPVD more frequently presented with plantar or proximal ulcers confined to a single extremity, whereas TAO was characterized by bilateral or multi-extremity involvement and distal acral ulceration. Antiplatelet and statin therapy, revascularization, and rates of major amputation, all-cause mortality, and hospitalization were higher in patients with DPVD (all p < 0.05). On multivariate analysis, age, cumulative smoking exposure, SIRI, and CRI-I independently distinguished DPVD from TAO (all p < 0.05). In the isolated distal DPVD subgroup, despite similar distal anatomy, inflammatory/atherogenic burden, and overall clinical risk remained adverse. Conclusions: TAO and DPVD are two distinct phenotypes with different pathobiologies and prognoses, despite similar distal ischemia presentations. Simple inflammatory and atherogenic composite indices, evaluated in conjunction with clinical/ulcer patterns, may support the differential diagnosis and risk stratification of patients with peripheral arterial disease (PAD). However, prospective multicenter validation of these findings is required to confirm the results.
  • Comparison of atherogenic indices and systemic inflammation in peripheral artery disease based on localization
    Murat Yucel, Muhammet Fethi Saglam, Kemal Esref Erdogan, Emrah Uguz
    Turkish Journal of Vascular Surgery, 2026
    Aim: Peripheral artery disease (PAD) is a heterogeneous atherosclerotic process shaped by segment-specific lipid and inflammatory mechanisms. This study aimed to evaluate the diagnostic and predictive value of these parameters in distinguishing disease localization by comparing atherogenic (AIP, CRI-I/II) and systemic inflammatory (SIRI, AISI, NLR, SII) biomarker profiles between proximal and distal PAD. Material and Methods: This single-center retrospective cohort study (2020–2025) screened 782 patients with PAD confirmed by angiography. After propensity score matching for key covariates, 150 proximal and 150 distal cases were analyzed. Laboratory data from ±14 days of the imaging date were used to calculate the lipid (AIP, CRI-I, CRI-II) and hematological-inflammatory indices (NLR, SII, SIRI, AISI). Comparative, regression, and ROC analyses were performed. Results: In distal PAD, AIP, SIRI, AISI, and CRP values were significantly higher, whereas in proximal PAD, CRI-I/II and NLR values were higher. In multivariate analysis, SIRI remained the strongest independent predictor of distal disease. ROC analysis identified SIRI as the most sensitive predictor of distal PAD and CRI-II as the most specific predictor of proximal PAD. Clinically, distal PAD is associated with a high prevalence of diabetes mellitus (DM) and chronic kidney disease (CKD). Conclusion: This study highlights that readily accessible hematological and lipid-derived indices can distinguish between proximal and distal PAD phenotypes, reflecting different pathophysiological mechanisms. This study aimed to integrate these inexpensive biomarkers into clinical assessment to improve early risk classification, guide phenotype-specific treatment, support personalized treatment strategies, and ultimately improve clinical decision-making in patients with PAD.
  • Evaluation of Myocardial Protection in Prolonged Aortic Cross-Clamp Times: Del Nido and HTK Cardioplegia in Adult Cardiac Surgery
    Murat Yücel, Emre Demir Benli, Kemal Eşref Erdoğan, Muhammet Fethi Sağlam, Gökay Deniz, Hakan Çomaklı, Emrah Uğuz
    Medicina Lithuania, 2025
    Background and Objectives: Effective myocardial protection is essential for successful cardiac surgery outcomes, especially in complex and prolonged procedures. To this end, Del Nido (DN) and histidine-tryptophan-ketoglutarate (HTK) cardioplegia solutions are widely used; however, their comparative efficacy in adult surgeries with prolonged aortic cross-clamp (ACC) times remains unclear. This study aimed to compare the efficacy and safety of DN and HTK for myocardial protection during prolonged ACC times in adult cardiac surgery and to define clinically relevant thresholds. Materials and Methods: This retrospective study included a total of 320 adult patients who underwent cardiac surgery under cardiopulmonary bypass (CPB) with an aortic cross-clamp time ≥ 90 min. Data were collected from the medical records of elective adult cardiac surgery cases performed at a single center between 2019 and 2025. Patients were categorized into two groups based on the type of cardioplegia received: Del Nido (n = 160) and HTK (n = 160). The groups were compared using 1:1 propensity score matching. Clinical and biochemical outcomes—including troponin I (TnI), CK-MB, lactate levels, incidence of low cardiac output syndrome (LCOS), and need for mechanical circulatory support—were analyzed between the two cardioplegia groups. Subgroup analyses were performed according to ACC duration (90–120, 120–150, 150–180 and >180 min). The predictive threshold of ACC duration for each complication was determined by ROC analysis, followed by the analysis of independent predictors of each endpoint by multivariate logistic regression. Results: Intraoperative cardioplegia volume and transfusion requirements were lower in the DN group (p < 0.05). HTK was associated with lower TnI levels and less intra-aortic balloon pump (IABP) requirement at ACC times exceeding 180 min. Markers of myocardial injury were lower in patients with an ACC duration of 120–150 min in favor of HTK. The propensity for ventricular fibrillation after ACC was significantly lower in the DN group. Significantly lower postoperative sodium levels were observed in the HTK group. Prolonged ACC duration was an independent risk factor for LCOS (odds ratio [OR]: 1.023, p < 0.001), VIS > 15 (OR, 1.015; p < 0.001), IABP requirement (OR: 1.020, p = 0.002), and early mortality (OR: 1.016, p = 0.048). Postoperative ejection fraction (EF), troponin I, and CK-MB levels were associated with the development of LCOS and a VIS > 15. Furthermore, according to ROC analysis, HTK cardioplegia was able to tolerate ACC for up to a longer duration in terms of certain complications, suggesting a higher physiological tolerance to ischemia. Conclusions: ACC duration is a strong predictor of major adverse outcomes in adult cardiac surgeries. Although DN cardioplegia is effective and economically advantageous for shorter procedures, HTK may provide superior myocardial protection in operations with long ACC duration. This study supports the need to individualize cardioplegia choice according to ACC duration. Further prospective studies are needed to establish standard dosing protocols and to optimize cardioplegia selection according to surgical duration and complexity.
  • Predictive Role of Systemic Inflammatory Indices in Surgically Managed Postpericardiotomy Syndrome Following Cardiac Surgery
    Murat Yücel, Emrah Uğuz, Muhammet Fethi Sağlam, Kemal Eşref Erdoğan, Mete Hıdıroğlu, Altay Alili, Şeref Alp Küçüker
    Diagnostics, 2025
    Objective: This study aimed to evaluate the prognostic utility of systemic inflammatory markers, such as the Systemic Immune-Inflammation Index (SII), Systemic Inflammatory Response Index (SIRI), Neutrophil–Lymphocyte Ratio (NLR), Monocyte–Lymphocyte Ratio (MLR), and Platelet–Lymphocyte Ratio (PLR), to identify patients at risk of developing surgically treated postpericardiotomy syndrome (PPS). Methods: A total of 150 patients were retrospectively analyzed. In total, 75 patients who developed postpericardiotomy syndrome requiring surgical drainage constituted the postpericardiotomy group, whereas 75 age- and surgically matched non-PPS patients served as the control group. Blood samples were collected at four time points: preoperative (T1), 24 h postoperative (T2), 7 days postoperative (T3), and 24 h before secondary intervention in the PPS group and the closest matched outpatient follow-up (T4) in the control group. Inflammatory marker values were compared within and between the groups at the four defined time points. Logistic regression and receiver operating characteristic (ROC) analyses were used to determine the diagnostic and predictive accuracy of each marker. Results: Significant increases in the SIRI, MLR, and CRP levels were observed in patients who developed PPS and required surgical intervention. MLR on postoperative day 7 had the highest sensitivity (84%) with a cut-off of 0.575, whereas SIRI demonstrated the highest specificity (81.3%) at a cut-off of 3.34. SII increased significantly only in the late stage, indicating disease progression. The NLR lacked predictive power across all time points. Conclusions: The SIRI and MLR are promising early-stage biomarkers for identifying patients at high risk of developing PPS. Their integration into routine postoperative follow-up could facilitate earlier diagnosis and reduce surgical burden. A multi-marker approach may enhance the diagnostic precision of PPS beyond that of traditional inflammatory measures.
  • Efficacy of Single-Dose Del Nido Cardioplegia Beyond 90 Minutes in Adult Cardiac Surgery
    Murat Yücel, Emrah Uğuz, Kemal Eşref Erdoğan, Erol Şener
    Journal of Clinical Medicine, 2025
    Background: Del Nido (DN) cardioplegia is widely used in cardiac surgery for its efficacy in providing myocardial protection for up to 90 min with a single dose. However, its safety and efficacy during prolonged ischemia remain unclear. Methods: This retrospective study analyzed 471 patients who underwent cardiac surgery with CPB between January 2019 and September 2024. Patients were divided into two groups: ACC durations of 60–90 min (Group A, n = 240) and >90 min (Group B, n = 231). The perioperative characteristics, clinical outcomes, and biochemical markers were compared to evaluate the impact of prolonged ischemia. Results: Patients in Group B exhibited significantly higher postoperative troponin I and lactate levels at 4 h post-CPB, suggesting increased myocardial and metabolic stress. Lactate levels normalized within 24 h, indicating transient myocardial dysfunction. Defibrillation requirements and vasoactive inotropic score (VIS) were also significantly elevated in Group B, reflecting compromised myocardial electrical stability and hemodynamic challenges. However, the long-term outcomes such as mortality, LCOS, and MODS showed no significant differences between the groups. Conclusions: While DN cardioplegia provides sufficient myocardial protection for ACC durations within 90 min, its efficacy diminishes during prolonged ischemia, as evidenced by increased myocardial injury and hemodynamic instability. Tailored strategies, including standardized redosing protocols and enhanced perioperative management, are essential for optimizing outcomes in complex surgeries with extended ischemia times. Further prospective studies are needed to refine these protocols and assess alternative solutions for myocardial protection.
  • Clinical outcomes of endovascular repair in ruptured aortic pathologies: A single center experience with TEVAR and EVAR procedures
    , Muhammet Fethi Saglam, Emrah Uguz, , Kemal Esref Erdogan, , Huseyin Unsal Ercelik, , Murat Yucel, , Mete Hidiroglu, , Murat Canyigit, , Erol Sener, and
    Turkish Journal of Vascular Surgery, 2025
    Aim: Aortic ruptures are critical vascular emergencies with high mortality rates, typically involving the thoracic and abdominal regions. This study aims to evaluate the clinical outcomes of Thoracic Endovascular Aortic Repair (TEVAR) and Endovascular Aneurysm Repair (EVAR) procedures in patients with ruptured thoracic and abdominal aortic pathologies, focusing on mortality, morbidity, and complications. Material and Methods: This retrospective, single-center study included 32 patients treated with endovascular interventions for ruptured aortic pathologies between 2019 and 2024. Fourteen patients with thoracic aortic rupture received TEVAR, while eighteen with abdominal aortic rupture underwent EVAR. The causes of rupture were classified as aortic transection (due to trauma), type-3 dissection, aneurysm, pseudoaneurysm, aorto-enteric fistula, and iatrogenic perforation. Demographic and clinical data, procedural details, and post-operative outcomes were collected and analyzed. Results: The primary causes of rupture included aortic transection (50%) in the TEVAR group and aneurysm (56.2%) in the EVAR group. Mortality rates were 14.3% in the TEVAR group and 27.8% in the EVAR group, while morbidity rates were 7.1% and 16.7%, respectively. Intensive care unit (ICU) and ward stays were significantly longer in the TEVAR group. Follow-up imaging showed normal results in 100% of TEVAR patients and in 88.9% of EVAR patients; endoleak was observed in 11.1% of the EVAR group (p<0.05). In the logistic regression analysis, the presence of complications was identified as a significant risk factor for mortality (OR=3.06, 95% CI: 1.04–8.97; p=0.04). Conclusion: TEVAR and EVAR are effective endovascular treatment modalities that provide high efficacy and safety in managing ruptured aortic pathologies, especially in emergency settings. The capability to perform hybrid procedures promptly in urgent cases underscores the adaptability and rapid applicability of endovascular therapies. Despite the inherent challenges of ruptured aortic pathologies, our study emphasizes the clinical importance of TEVAR in thoracic and EVAR in abdominal aortic ruptures, offering valuable insights that enhance the current literature.
  • A Retrospective Analysis of Standardized Gradient Calculations for Evaluating Patient–Prosthesis Mismatch Following Mechanical Aortic Valve Replacement
    Muhammet Fethi Sağlam, Emrah Uguz, Kemal Eşref Erdogan, Hüseyin Ünsal Erçelik, Murat Yücel, Altay Alili, Nur Gizem Elipek, Okay Güven Karaca, Erol Şener
    Diagnostics, 2025
    Background: Aortic stenosis (AS) is one of the most common valvular heart diseases, particularly in the elderly, with a prevalence of approximately 3% in individuals over 75 years of age. Aortic valve replacement (AVR) remains the standard treatment, yet postoperative hemodynamic assessment is often complicated by variations in prosthetic valve size, left ventricular ejection fraction (LVEF), effective orifice area (EOA), and body surface area (BSA). These factors significantly influence prosthetic valve function and contribute to patient–prosthesis mismatch (PPM), which has been associated with worse clinical outcomes. Traditional transvalvular gradient measurements often fail to account for these patient-specific variables. This study introduces a novel approach to standardized gradient calculations, aiming to enhance the accuracy and comparability of prosthetic valve assessments. Methods: A retrospective analysis was conducted on 115 patients who underwent mechanical AVR at a single center. Patients were categorized into three groups based on the prosthetic valve type: St. Jude Medical (SJM) HP (n = 31); SJM Regent (n = 54); and those who underwent aortic root enlargement (ARE) (n = 30). Preoperative and postoperative transthoracic echocardiography (TTE) was performed to measure conventional and standardized transvalvular gradients. Four novel standardized gradient calculations were developed to adjust for individual hemodynamic differences, improving the accuracy of prosthetic valve function assessment. Results: Standardized gradient calculations demonstrated significant differences between prosthesis types. Postoperative standardized gradients were significantly higher in the SJM HP group compared to the SJM Regent and aortic-root-enlargement groups (p < 0.001, p < 0.05). The lowest standardized gradients were observed in patients who received the SJM Regent prostheses (p < 0.05). Although conventional measurements showed no significant differences, standardized calculations revealed that patients with 19 mm prostheses exhibited significantly higher transvalvular gradients than those with 21 mm prostheses (p < 0.05), emphasizing the clinical importance of prosthesis size in postoperative hemodynamics. Conclusions: Standardized gradient calculations provide a more objective, reliable, and patient-specific assessment of prosthetic valve function by minimizing interpatient variability. This approach improves the detection of patient–prosthesis mismatch and optimizes postoperative hemodynamic evaluation, potentially leading to better prosthesis selection and surgical decision-making. However, further validation is required in larger cohorts before these methods can be widely adopted into clinical practice. Future studies should assess their impact on long-term clinical outcomes, including left ventricular remodeling and patient survival.
  • Stuck Prosthetic Valves: Clinical Implications of Pannus Formation and Gradient Measurement in Surgical Outcomes
    Muhammet Fethi Sağlam, Emrah Uguz, Kemal Eşref Erdogan, Hüseyin Ünsal Erçelik, Murat Yücel, Mete Hıdıroglu, Erol Şener
    Journal of Clinical Medicine, 2025
    Objective: Stuck prosthetic valves, often resulting from pannus formation or thrombus accumulation, represent a critical complication in prosthetic valve management, carrying significant risks for morbidity and mortality. This study aims to identify factors associated with stuck valve development and assess the effectiveness of interventions in restoring normal valve function. Methods: A total of 27 patients with stuck valves were analyzed, including mitral, aortic, and tricuspid valve cases. Metallic valves were initially implanted in all patients. Interventions included pannus cleaning in suitable cases and valve replacement when necessary, with the replacement being either metallic and biological based on clinical indications. Preoperative and postoperative ECG rhythms, left ventricular ejection fraction (LVEF) values, and gradient measurements were evaluated across patient groups. Results: No significant difference was found in time since initial surgery across valve types (p = 0.67), except in mitral valves, where time was longer in the replacement group (p = 0.02). Maximum gradients were higher in the pannus cleaning group for mitral valves (p = 0.03), while overall gradient values showed no significant differences. Postoperative left ventricular ejection fraction improved significantly in all groups (p < 0.001). Conclusions: The findings highlight the importance of timely intervention in managing stuck prosthetic valves, which are associated with severe hemodynamic compromise and embolic risk. Pannus cleaning emerged as a viable alternative in selected cases where the obstruction was localized, with the valve structure otherwise intact. Biological valve replacements demonstrated superior rhythm stabilization in this study, although definitive conclusions are constrained by the minimal sample size (n = 2). Future research should focus on expanding sample sizes and incorporating comprehensive preoperative analyses to better inform surgical and clinical management strategies.
  • Cardiac surgery dilemmas: evaluating outcomes of sternotomy versus thoracotomy
    MUHAMMET FETHİ SAĞLAM, EMRAH UGUZ, KEMAL EŞREF ERDOGAN, HÜSEYİN ÜNSAL ERÇELİK, MURAT YÜCEL, METE HIDIROGLU, EROL ŞENER
    Turkish Journal of Medical Sciences, 2025
  • [MSB-34] Clinical Outcomes and Applications of Bypass Procedures on Intra-Abdominal Visceral Arteries
    Muhammet Fethi Sağlam, Emrah Uğuz
    Turkish Journal of Thoracic and Cardiovascular Surgery, 2024
  • Postoperative Aortic Valve Insufficiency: Outcomes of Aortic Valve Preservation in Type A Aortic Dissection
    Kemal Eşref Erdoğan, Emrah Uğuz, Nur Gizem Elipek
    Turkish Journal of Thoracic and Cardiovascular Surgery, 2024
  • Comparison of Plegisol and del Nido Cardioplegia on Right Ventricular Function and Outcomes in Cardiac Surge
    Alp Yıldırım, Enis Burak Gül, Mehmet Erdoğan, Emrah Uğuz
    Turkish Journal of Thoracic and Cardiovascular Surgery, 2024
  • Comparative Analysis of Mechanical and Bioprosthetic Valves in Tricuspid Valve Replacement
    Cevat Ahmet Sert, Emrah Uguz, Muhammet Fethi Sağlam, Hüseyin Ünsal Erçelik, Erol Şener
    Turkish Journal of Thoracic and Cardiovascular Surgery, 2024
  • Effects of Early Coronary Artery Bypass Grafting on Stent and Graft Patency Following Successful Stenting for Acute Coronary Syndromes
    Fatih Yamaç, Emrah Uğuz, Kemal Eşref Erdoğan, Muhammet Fethi Sağlam, Hüseyin Ünsal Erçelik
    Turkish Journal of Thoracic and Cardiovascular Surgery, 2024
  • Risk factors for chronic venous insufficiency in nurses in Türkiye-NueVo TR
    , Hakki Tankut Akay, Soner Yavas, , Emrah Uguz, , Mustafa Sirlak, , Evren Ozcinar, , Ali Umit Yener, , Adnan Yalcinkaya, , Senol Yavuz, , Kadir Kaan Ozsin, , Mehmet Ali Kaygin, , Unal Aydin, , Ugur Kisa, , Adil Polat, , Ali Aycan Kavala, , Emrah Oguz, , Tanzer Calkavur, , Ismail Yurekli, , Serdar Bayrak, , Omer Tanyeli, , Kaptaniderya Tayfur, , Sefer Usta, , Ibrahim Ozsoyler, , Suat Karaca, , Baris Erdal, , Nevzat Erdil, and
    Turkish Journal of Vascular Surgery, 2024
  • Assessment of patient characteristics in cancer-associated venous thrombosis in Türkiye (CAT-TR study)
    , Orcun Unal, Hakkı Tankut Akay, , Suat Dogancı, , Ahmet Kursat Bozkurt, , Nevzat Erdil, , Mustafa Sirlak, , Emrah Uguz, , Dilek Erer, Abdullah Ozer, Deniz Serefli, Soner Yavas, Kemal Esref Erdogan, Mustafa Seren, Evren Ozcinar, Emre Kubat, Adil Polat, Kamil Boyacioglu, Cengiz Koksal, Emre Selcuk, Ozan Onur Balkanay, Ismet Tanzer Calkavur, Emrah Oguz, Ismail Yurekli, Koksal Donmez, Erdem Cetin, Celal Selcuk Unal, Kaptaniderya Tayfur, Mehmet Ali Kayfın, Mustafa Edis, Omer Tanyeli, Rifat Ozmen, Okan Ozocak, Senol Yavuz, Kadir Kaan Ozsin
    Turkish Journal of Vascular Surgery, 2023
  • Prevalence and incidence of deep venous thrombosis and pulmonary embolism in 2 regions in Turkey (A sub-analysis of CAT-TR study)
    Hakkı Tankut Akay, Orcun Unal, Suat Doganci, Ahmet Kursat Bozkurt, Nevzat Erdil, Mustafa Sirlak, Emrah Uğuz
    Turkish Journal of Vascular Surgery, 2023
  • Transcarotid transcatheter aortic valve implantation with a novel balloon expandable Myval® THV under the local anesthesia
    H. Ayhan, B. D. Karaduman, T. Keleş, E. Uğuz, E. Boysan, E. Bozkurt
    Journal of Geriatric Cardiology, 2022
  • Transcatheter aortic valve implantation via the left axillary artery route in a patient with a permanent pacemaker: The first transaxillary artery route experience with a Meril’s MyvalTM transaortic valve in Turkey
    , Telat Keles, Ozlem Ozcan Celebi, , Emrah Uguz, , Kevser Balci, , Engin Bozkurt, and
    Anatolian Journal of Cardiology, 2021
  • National guidelines on the management of venous thromboembolism: Joint guideline of the Turkish Society of Cardiovascular Surgery, National Society of Vascular and Endovascular Surgery, and Phlebology Society
    Ahmet Kürşat Bozkurt, Hakkı Tankut Akay, İsmet Tanzer Çalkavur, Mustafa Şırlak, Ozan Onur Balkanay, Emrah Uğuz, Suat Doğancı, Adil Polat, Serdar Bayrak, Şahin Bozok, Ahmet Barış Durukan, Nevzat Erdil, Dilek Erer, Şahin Şenay, Ertekin Utku Ünal, Soner Yavaş
    Turkish Journal of Thoracic and Cardiovascular Surgery, 2021
  • Surgical treatment of hydatid cyst infiltrating into myocardium and causing mitral valve regurgitation
    Kemal Eşref Erdoğan
    Turkish Journal of Thoracic and Cardiovascular Surgery, 2019
  • An unusual presentation of papillary fibroelastoma originating from right ventricular outflow tract
    Mehmet Erdogan, Murat Can Guney, Hüseyin Ayhan, Hacı Ahmet Kasapkara, Emrah Uğuz, Tahir Durmaz, Telat Keleş, Engin Bozkurt
    Echocardiography, 2017
  • Treatment of acute thoracic aortic syndromes using endovascular techniques
    Emrah Uguz, Murat Canyigit, Mete Hidiroglu, Erol Sener
    Diagnostic and Interventional Radiology, 2016
  • Predictability and Outcome of Vascular Complications after Transfemoral Transcatheter Aortic Valve Implantation
    Journal of Heart Valve Disease, 2016
  • Endovascular repair of type-V thoracoabdominal aortic aneurysms using parallel graft techniques
    Murat Canyiğit
    Turkish Journal of Thoracic and Cardiovascular Surgery, 2016
  • Expected and observed mortality in patients undergoing coronary artery bypass surgery
    Mecit GÖKÇİMEN, Emrah UĞUZ, Murat ÇİÇEK, Mete HIDIROĞLU, Erol ŞENER
    Turkiye Klinikleri Journal of Medical Sciences, 2015
  • Iliorenal periscope graft to maintain blood flow to accessory renal artery
    Murat Canyigit, Mete Hidiroglu, Emrah Uguz, Huseyin Cetin
    Diagnostic and Interventional Radiology, 2015
  • Patient–prosthesis mismatch increases the mean platelet volume in patients with aortic valve replacement
    Huseyin Bayram, Mete Hidiroglu, Levent Cetin, Omer Faruk Cicek, Aslihan Kucuker, Emrah Uguz, Kemal Esref Erdogan, Erol Sener
    Surgery Today, 2015
  • Endovascular aortic repair of pararenal aortic aneurysm with multibranched stent-graft: First successful experience in Turkey
    Murat Canyiğit
    Turkish Journal of Thoracic and Cardiovascular Surgery, 2015
  • Endovascular treatment for acute traumatic thoracic aortic transaction
    Onur Ergun
    Ulusal Travma Ve Acil Cerrahi Dergisi, 2015
  • The proinflammatory cytokine-mediated protective effects of pentoxifylline, iloprost, and cilostazol on a mitigating lung injury induced by lower limb ischemia and reperfusion in rats
    Mete Hıdıroğlu
    Turkish Journal of Thoracic and Cardiovascular Surgery, 2014
  • Explantation of an atrial septal occluder device in a patient with nickel hypersensitivity
    Emrah Uguz, Kemal Erdogan, Erol Sener
    Anadolu Kardiyoloji Dergisi, 2014
  • Ruptured sinus of Valsalva aneurysm and coarctation of aorta in a woman at early postpartum period
    Erol Sener, Aslihan Kucuker, Huseyin Bayram, Kadir Kurt, Emrah Uguz, Muhammed Fethi Saglam
    Case Reports in Medicine, 2014
  • Simultaneously successful transfemoral aortic valve implantation and endovascular repair of thoracic aortic saccular aneurysm
    Hüseyin Ayhan, Tahir Durmaz, Telat KeleŞ, Murat CanyiĞit, Emrah UĞuz, Hacı Ahmet Kasapkara, Engin Bozkurt
    International Heart Journal, 2014
  • Predictors and outcomes of minor cerebrovascular events after cardiac surgery: A multivariable analysis of 1346 patients
    Journal of Cardiovascular Surgery, 2013
  • Comparing S-100 beta protein levels and neurocognitive functions between patients undergoing on-pump and off-pump coronary artery bypass grafting
    Huseyin Bayram, Mete Hidiroglu, Levent Cetin, Aslihan Kucuker, Erkan Iriz, Emrah Uguz, Fethi Saglam, Erol Sener
    Journal of Surgical Research, 2013
  • Reduction of iodinated contrast load with the renal artery catheterization technique during endovascular aortic repair
    Murat Canyigit, Levent Cetin, Emrah Uguz, Oktay Algin, Aslihan Kucuker, Halil Arslan, Erol Sener
    Diagnostic and Interventional Radiology, 2013
  • Significant compression of saphenous vein graft caused by a protruding sternal wire
    Chirurgia Turin, 2013
  • Surgical repair of unruptured aneurysm of the left sinus of Valsalva with aortic stenosis, coronary artery disease and ascending and arcus aorta aneurysm
    Chirurgia Turin, 2013
  • Aortic valve replacement in a patient with factor VII deficiency
    Emrah Uğuz
    Turkish Journal of Thoracic and Cardiovascular Surgery, 2012
  • Sequential radial artery for coronary artery bypass grafting: Five-year follow-up and evaluation with multi-detector row computed tomography
    Mustafa Emir, Ayşe Gül Kunt, Murat Çiçek, Şahin Bozok, Sedat Ozan Karakişi, Emrah Uğuz, Mete Hidiroğlu, Levent Çetin, Erol Şener
    Cardiovascular Revascularization Medicine, 2012
  • Shunt usage in carotid artery surgery
    Ayşegül Kunt
    Turkish Journal of Thoracic and Cardiovascular Surgery, 2012
  • Management of extensive venous thrombosis following cardiac surgery in a patient with Behcet's disease
    Ilhan, Bozok, Uguz, Karamustafa, O. Karakisi, Sener
    Vasa Journal of Vascular Diseases, 2012
  • Surgical repair of coarctation of aorta in neonates and infants: A 10 years experience
    Turkish Journal of Thoracic and Cardiovascular Surgery, 2010
  • Cardiac transplant in a child with recurrent thrombosis due to congenital thrombophilic mutations
    Experimental and Clinical Transplantation, 2009
  • Mitral valve replacements in redo patients with previous mitral valve procedures: Mid-term results and risk factors for survival
    Tankut Hakki Akay, Bahadir Gultekin, Süleyman Ozkan, Erdal Aslim, Emrah Uguz, Atilla Sezgin, Sait Aslamaci
    Journal of Cardiac Surgery, 2008
  • Massive Ascites Due to Right Heart Failure After Cardiac Transplantation and Its Treatment: A Case Report
    A. Sezgin, E. Uǧuz, T. Akay, S. Aşlamacı
    Transplantation Proceedings, 2008
  • Surgical repair of tricuspid valve regurgitation caused by blunt thoracic trauma
    Rza Turkoz, Oner Gulcan, Hakan Atalay, Emrah Uguz
    Journal of Trauma Injury Infection and Critical Care, 2007
  • Diaphragmatic paralysis after cardiac surgery in children: Incidence, prognosis and surgical management
    Tankut Hakki Akay, Süleyman Ozkan, Bahadir Gultekin, Emrah Uguz, Birgul Varan, Atilla Sezgin, Kursad Tokel, Sait Aslamaci
    Pediatric Surgery International, 2006
  • Our experience in cardiac transplantation in Baskent University
    A. Sezgin, B. Gültekin, S. Özkan, T. Akay, E. Uğuz, ̇I. Tokalak, E. Akpek, A. Dönmez, H. Müderrisoğlu, S. Aslamaci
    Transplantation Proceedings, 2006
  • Low-dose histidine-tryptophan-ketoglutarate solution for myocardial protection
    A. Arslan, A. Sezgin, B. Gultekin, S. Ozkan, T. Akay, E. Uguz, A. Tasdelen, S. Aslamaci
    Transplantation Proceedings, 2005
  • Valve replacement surgery in patients with end-stage renal disease: Long-term results
    Bahadir Gultekin, Suleyman Ozkan, Emrah Uguz, Hakan Atalay, Tankut Akay, Ahmet Arslan, Atilla Sezgin, Nurhan Ozdemir, Atilay Tasdelen, Sait Aslamaci
    Artificial Organs, 2005
  • Mitral valve replacement after application of atrial appendix flap in endocarditis with posterior annular abscess
    R TURKOZ, O GULCAN, E UGUZ, H CIHAN
    European Journal of Cardio Thoracic Surgery, 2004

RECENT SCHOLAR PUBLICATIONS

  • De Ritis Ratio as an Independent Predictor of In-Hospital Mortality in Surgically Treated Acute Aortic Dissection
    KE Erdoğan, B Kardeşler, MF Sağlam, E Uğuz, M Yücel, S Turgut, ...
    Journal of Clinical Medicine 15 (9), 3419 , 2026
    2026
  • Diabetic Peripheral Arterial Disease Versus Thromboangiitis Obliterans: A Multidimensional Comparison of Clinical Phenotype, Biomarkers, and Outcomes
    M Yücel, H Çomaklı, MF Sağlam, KE Erdoğan, NG Elipek, ÖA Yavuz, ...
    Diagnostics 16 (4), 560 , 2026
    2026
  • Comparison of atherogenic indices and systemic inflammation in peripheral artery disease based on localization
    M Yucel, M SAĞLAM, K ERDOĞAN, E UĞUZ
    Turkish Journal of Vascular Surgery 35 (1) , 2026
    2026
  • Clinical utility of hematological inflammatory indices in predicting pulmonary embolism in patients with lower extremity deep vein thrombosis
    M Yucel, H Comakli, G Deniz, M SAĞLAM, K ERDOĞAN, E UĞUZ, B Benli
    Turkish Journal of Vascular Surgery 35 (1) , 2026
    2026
  • Predictive Role of Systemic Inflammatory Indices in Surgically Managed Postpericardiotomy Syndrome Following Cardiac Surgery
    M Yücel, E Uğuz, MF Sağlam, KE Erdoğan, M Hıdıroğlu, A Alili, ...
    Diagnostics 15 (12), 1488 , 2025
    2025
    Citations: 8
  • Predictive Role of Systemic Inflammatory Indices in Surgically Managed Dressler Syndrome Following Cardiac Surgery
    M Yücel, E Uğuz, MF Sağlam, KE Erdoğan, M Hıdıroğlu, A Alili, ...
    Preprints , 2025
    2025
  • Efficacy of Single-Dose Del Nido Cardioplegia Beyond 90 Minutes in Adult Cardiac Surgery
    ŞE Yücel Murat, Uğuz Emrah, Erdoğan Kemal Eşref
    Journal of Clinical Medicine 14 (7), 2248 , 2025
    2025
  • Artificial Intelligence in Patient Communication: Performance of GPT-3.5 and GPT-4 in Coronary Bypass Surgery
    MF Sağlam, E Uğuz, K Erdoğan, HÜ Erçelik, M Yücel, CA Sert, F Yamac, ...
    Konuralp Medical Journal 17 (1), 100-105 , 2025
    2025
  • Impact of Surgeon Experience on Clinical Outcomes in Cardiovascular Surgery: A Retrospective Analysis
    MF Sağlam, E Uğuz, K Erdoğan, HÜ Erçelik, M Yücel, E Sener
    Online Turkish Journal of Health Sciences 10 (1), 82-88 , 2025
    2025
  • Kardiyovasküler Cerrahide Cerrah Deneyiminin Klinik Sonuçlar Üzerindeki Etkisi: Retrospektif Bir Analiz
    M Sağlam, E Uguz, K ERDOĞAN, E Şener
    Online Türk Sağlık Bilimleri Dergisi 10 (1) , 2025
    2025
  • The effect of cardioplegia techniques on left ventricular functions in coronary artery bypass grafting: A comparison with tissue Doppler echocardiography
    S TURAN, E Uguz, T Karabag
    Cardiovascular surgery and interventions 12 (2) , 2025
    2025
  • Cardiac surgery dilemmas: evaluating outcomes of sternotomy versus thoracotomy
    MF Sağlam, E Uguz, KE ERDOGAN, HÜ Erçelik, M Yuecel, M Hidiroglu, ...
    Turkish Journal of Medical Sciences 55 (2), 482-487 , 2025
    2025
  • Clinical outcomes of endovascular repair in ruptured aortic pathologies: A single center experience with TEVAR and EVAR procedures
    M SAĞLAM, E UĞUZ, K ERDOĞAN, H Ercelik, M Yucel, M HIDIROĞLU, ...
    Turkish Journal of Vascular Surgery 34 (1) , 2025
    2025
  • [MSB-29] Comparative Analysis of Mechanical and Bioprosthetic Valves in Tricuspid Valve Replacement
    CA Sert, E Uguz, MF Sağlam, HÜ Erçelik, E Şener
    Turkish Journal of Thoracic and Cardiovascular Surgery 32 (4 Suppl 2), 050 , 2024
    2024
  • [MSB-34] Clinical Outcomes and Applications of Bypass Procedures on Intra-Abdominal Visceral Arteries
    MF Sağlam, E Uğuz
    Turkish Journal of Thoracic and Cardiovascular Surgery 32 (4 Suppl 2), 058 , 2024
    2024
  • [MSB-49] Postoperative Aortic Valve Insufficiency: Outcomes of Aortic Valve Preservation in Type A Aortic Dissection
    KE Erdoğan, E Uğuz, NG Elipek
    Turkish Journal of Thoracic and Cardiovascular Surgery 32 (4 Suppl 2), 074 , 2024
    2024
  • [MSB-08] Comparison of Plegisol and del Nido Cardioplegia on Right Ventricular Function and Outcomes in Cardiac Surgery
    A Yıldırım, EB Gül, M Erdoğan, E Uğuz
    Turkish Journal of Thoracic and Cardiovascular Surgery 32 (4 Suppl 2), 025 , 2024
    2024
  • [MSB-19] Effects of Early Coronary Artery Bypass Grafting on Stent and Graft Patency Following Successful Stenting for Acute Coronary Syndromes
    F Yamaç, E Uğuz, KE Erdoğan, MF Sağlam, HÜ Erçelik
    Turkish Journal of Thoracic and Cardiovascular Surgery 32 (4 Suppl 2), 038 , 2024
    2024
  • Impact of Right Ventricular Function on Mortality and Reoperation Rates in Cardiovascular Surgery
    MF Sağlam, E Uğuz, K Erdoğan, HÜ Erçelik, M Yücel, M Hıdıroğlu, ...
    Sakarya Tıp Dergisi 14 (4), 388-397 , 2024
    2024
  • Physician-Valvular Diseases and Surgery [MSB-29]
    CA Sert, E Uguz, MF Sağlam, HÜ Erçelik, E Şener
    Turkish Journal of Thoracic and Cardiovascular Surgery 32 (2), 13-96 , 2024
    2024

MOST CITED SCHOLAR PUBLICATIONS

  • Diaphragmatic paralysis after cardiac surgery in children: incidence, prognosis and surgical management
    TH Akay, S Ozkan, B Gultekin, E Uguz, B Varan, A Sezgin, K Tokel, ...
    Pediatric surgery international 22 (4), 341-346 , 2006
    2006
    Citations: 108
  • Low-dose histidine-tryptophan-ketoglutarate solution for myocardial protection
    A Arslan, A Sezgin, B Gultekin, S Ozkan, T Akay, E Uguz, A Tasdelen, ...
    Transplantation proceedings 37 (7), 3219-3222 , 2005
    2005
    Citations: 67
  • Mitral valve replacements in redo patients with previous mitral valve procedures: mid‐term results and risk factors for survival
    TH Akay, B Gultekin, S Ozkan, E Aslim, E Uguz, A Sezgin, S Aslamaci
    Journal of cardiac surgery 23 (5), 415-421 , 2008
    2008
    Citations: 38
  • Comparing S-100 beta protein levels and neurocognitive functions between patients undergoing on-pump and off-pump coronary artery bypass grafting
    H Bayram, M Hidiroglu, L Cetin, A Kucuker, E Iriz, E Uguz, F Saglam, ...
    Journal of Surgical Research 182 (2), 198-202 , 2013
    2013
    Citations: 30
  • Predictability and Outcome of Vascular Complications after Transfemoral Transcatheter Aortic Valve Implantation.
    E Uguz, M Gokcimen, S Ali, Y Alsancak, S Bastug, H Ahmet Kasapkara, ...
    The Journal of heart valve disease 25 (2), 173-181 , 2016
    2016
    Citations: 23
  • Reduction of iodinated contrast load with the renal artery catheterization technique during endovascular aortic repair
    M Canyigit, L Çetin, E Uguz, O Algin, A Küçüker, H Arslan, E Sener
    Diagnostic and Interventional Radiology 19 (3), 244 , 2013
    2013
    Citations: 18
  • Valve Replacement Surgery in Patients With End‐stage Renal Disease: Long‐term Results
    B Gultekin, S Ozkan, E Uguz, H Atalay, T Akay, A Arslan, A Sezgin, ...
    Artificial organs 29 (12), 972-975 , 2005
    2005
    Citations: 18
  • Simultaneously successful transfemoral aortic valve implantation and endovascular repair of thoracic aortic saccular aneurysm
    H Ayhan, T Durmaz, T KeleŞ, M CanyiĞit, E UĞuz, HA Kasapkara, ...
    International Heart Journal 55 (5), 459-462 , 2014
    2014
    Citations: 16
  • Explantation of an atrial septal occluder device in a patient with nickel hypersensitivity
    E Uguz, K Erdogan, E Sener
    The Anatolian Journal of Cardiology 14 (4), 402 , 2014
    2014
    Citations: 11
  • Surgical repair of coarctation of aorta in neonates and infants: a 10 years experience
    E Uğuz, S Özkan, H Akay, B Gültekin, S Aşlamaci
    Turkish Journal of Thoracic and Cardiovascular Surgery 18 (2) , 2010
    2010
    Citations: 11
  • Sequential radial artery for coronary artery bypass grafting: five-year follow-up and evaluation with multi-detector row computed tomography
    M Emir, AG Kunt, M Çiçek, Ş Bozok, SO Karakişi, E Uğuz, M Hidiroğlu, ...
    Cardiovascular Revascularization Medicine 13 (5), 272-276 , 2012
    2012
    Citations: 9
  • Predictive Role of Systemic Inflammatory Indices in Surgically Managed Postpericardiotomy Syndrome Following Cardiac Surgery
    M Yücel, E Uğuz, MF Sağlam, KE Erdoğan, M Hıdıroğlu, A Alili, ...
    Diagnostics 15 (12), 1488 , 2025
    2025
    Citations: 8
  • Predictors and outcomes of minor cerebrovascular events after cardiac surgery: a multivariable analysis of 1346 patients.
    A Kunt, Ç Atbaş, M Hidiroğlu, L Cetin, K Eşref Erdoğan, A Küçüker, ...
    The Journal of cardiovascular surgery 54 (4), 537-543 , 2013
    2013
    Citations: 8
  • Mitral valve replacement after application of atrial appendix flap in endocarditis with posterior annular abscess
    R Turkoz, O Gulcan, E Uguz, HB Cihan
    European journal of cardio-thoracic surgery 26 (4), 837-838 , 2004
    2004
    Citations: 8
  • Surgical repair of tricuspid valve regurgitation caused by blunt thoracic trauma
    R Turkoz, O Gulcan, H Atalay, E Uguz
    Journal of Trauma and Acute Care Surgery 63 (1), E7-E9 , 2007
    2007
    Citations: 7
  • National guidelines on the management of venous thromboembolism: Joint guideline of the Turkish Society of Cardiovascular Surgery, National Society of Vascular and Endovascular …
    AK Bozkurt, HT Akay, İT Çalkavur, M Şırlak, OO Balkanay, E Uğuz, ...
    Turkish Journal of Thoracic and Cardiovascular Surgery 29 (4), 562 , 2021
    2021
    Citations: 6
  • Endovascular treatment for acute traumatic thoracic aortic transection.
    O Ergun, M Canyiğit, M Hıdıroğlu, İG Tatar, E Birgi, A Küçüker, E Uguz, ...
    Turkish Journal of Trauma & Emergency Surgery/Ulusal Travma ve Acil Cerrahi … , 2015
    2015
    Citations: 6
  • Iliorenal periscope graft to maintain blood flow to accessory renal artery
    M Canyigit, M Hidiroglu, E Uguz, H Cetin
    Diagnostic and Interventional Radiology 21 (4), 334 , 2015
    2015
    Citations: 6
  • Management of extensive venous thrombosis following cardiac surgery in a patient with Behcet’s disease
    G İlhan, S Bozok, E Uguz, H Karamustafa, SO Karakisi, E Sener
    Vasa 41 (4), 301-305 , 2012
    2012
    Citations: 6
  • Risk factors for chronic venous insufficiency in nurses in Türkiye-NueVo TR
    H Akay, S Yavas, E Uğuz, M Şırlak, E Özçınar, A Yener, A Yalcinkaya, ...
    Turkish Journal of Vascular Surgery 33 (1) , 2024
    2024
    Citations: 5