Possui graduação em Medicina Veterinária pela Universidade Federal de Mato Grosso do Sul (2011) , em Ciência Animal pela Universidade Federal de Mato Grosso do Sul (2014) e em Ciência Animal pela Universidade Federal de Mato Grosso do Sul (2018) . Atualmente é Professor Adjunto A da Universidade Federal de Mato Grosso do Sul.
Efficiency of fluralaner pour-on in different strategic control protocols against Rhipicephalus microplus on Brangus cattle in a tropical area Guilherme Henrique Reckziegel, Mariana Green de Freitas, Juliane Francielle Tutija, Vinícius Duarte Rodrigues, Dyego Gonçalves Lino Borges, Murilo Damasceno Brunet de Freitas, Tiago Gallina, Welber Daniel Zanetti Lopes, Daniel de Castro Rodrigues, Heitor de Oliveira Arriero Amaral, Tom Strydom, Siddhartha Torres, Fernando de Almeida Borges Parasites and Vectors, 2024 Background The occurrence of higher winter temperatures in Brazilian areas with tropical and highland climates may result in a fifth peak of tick populations during winter in addition to the four generations previously described. Therefore, a strategic control protocol was developed with treatments in two seasons with the objective of controlling the generations of ticks that occur in spring/summer and those that occur in autumn/winter. Methods The study was conducted in Mato Grosso do Sul, Brazil, from the beginning of the rainy season, November 2020, to October 2021. In a randomized block design, 36 calves were distributed into three groups: (i) negative control; (ii) traditional strategic control in one season (SC1S), at the beginning of the rainy season; and (iii) strategic control in two seasons (SC2S), at the beginning and end of the rainy season. The SC1S strategic control group was treated on day 0, November 2020, and twice more with intervals of 42 days. The SC2S group received three more treatments beginning on day 182, May 2021, with intervals of 42 days. All treatments consisted of 5% fluralaner (Exzolt® 5%) delivered via a pour-on dose of 1 mL/20 kg body weight. Counts of semi-engorged female ticks were performed on day 3 and every 14 days thereafter, and the animals were weighed at the same time. Results Fluralaner showed a mean efficacy of more than 95% up to day 294. The two treated groups showed a decrease (P < 0.05) in the average number of ticks on day 3. In the SC2S group, the means were close or equal to zero throughout the study, while in the SC1S group, the means did not differ (P > 0.05) from those of the control group from day 231 onward. The final mean weight gain of each group was 76.40 kg, 98.63 kg, and 115.38 kg for the control, SC1S, and SC2S groups, respectively, differing (P < 0.05) from each other. Conclusions Therefore, three applications of fluralaner, with one application every 42 days from the beginning of the rainy season in the middle spring, resulted in effective tick control for 224 days. When three additional treatments were given in autumn/winter with intervals of 42 days between applications, tick counts were reduced throughout the year. This strategic control approach may be indicated in years with climatic conditions that allow that population peaks are expected to occur in the autumn/winter period. Graphical Abstract
Biomarkers of gastrointestinal nematodes in beef cattle raised in a tropical area Vinícius Duarte Rodrigues, Dyego Gonçalves Lino Borges, Mário Henrique Conde, Mariana Green de Freitas, Carlos Alberto do Nascimento Ramos, Alda Izabel de Souza, Guilherme Henrique Reckziegel, Daniel de Castro Rodrigues, Fernando de Almeida Borges Parasitology Research, 2024
Synergism of macrocyclic lactones against Haemonchus contortus Matheus Takemi Muchon Nakatani, Dyego Gonçalves Lino Borges, Mário Henrique Conde, Mariana Green de Freitas, Juliane Francielle Tutija, Vinícius Duarte Rodrigues, Guilherme Henrique Reckziegel, Carlos Alexandre Carollo, Fernando Almeida Borges Parasitology Research, 2023
Natural infestation by ticks as cause of death in beef cattle Carolina C. Guizelini, Dyego G.L. Borges, Fernando A. Borges, Welber D.Z. Lopes, Rayane C. Pupin, Ricardo A.A. Lemos Pesquisa Veterinaria Brasileira, 2023 Although infestation by Rhipicephalus microplus is mentioned as the cause of death among cattle, there are only studies with artificial infestations in which intense parasitism led to the death of cattle due to severe anemia. This study seems to be the first to describe the epidemiology, clinical-pathological condition, and diagnostic conduct of infestation by R. microplus as the cause of death of European breed calves introduced in shady, enclosed pastures in regions with rainfall prior to the onset of the outbreak. The affected calves presented apathy, anorexia, and anemia and were severely infested by R. microplus. The lethality rate of the outbreak was 36.5%. After the rainy period, the dry season facilitated a decrease in the nutritional status of the affected cattle. The delay in the definitive diagnosis contributed to the economic loss of the farm due to the cost of erroneous treatments and the number of dead cattle. The main factors that contributed to the deaths were climatic, environmental, and individual. This study demonstrates that severe infestations by R. microplus in low-quality pasture-raised calves are fatal and emphasizes the importance of diagnostic tools to reduce the economic loss caused by death due to infestation by ticks.
Moxidectin: A viable alternative for the control of ivermectin-resistant gastrointestinal nematodes in beef cattle Dyego Gonçalves Lino Borges, Mário Henrique Conde, Cibele Cristina Tavares Cunha, Mariana Green De Freitas, Elio Moro, Fernando De Almeida Borges Acta Veterinaria, 2022 The increasing prevalence of anthelmintic resistance in cattle especially for avermectins, is a challenge for controlling parasites in some herds. Thus, field studies demonstrating the increase in productivity by the use of anthelmintic formulations, even when a suboptimal treatment (efficacy below 95%), can contribute to the development of gastrointestinal nematodes control programs in beef cattle. The objective of the present study was to evaluate the anthelmintic efficacy and productive performance in pasture-raised beef calves, treated with macrocyclic lactones. A Split plot in time randomized block design was used to assess weight gain and reduction in fecal egg count (FECs) of treatments: 1% moxidectin (1% MOX), ivermectin (IVM) and abamectin (ABM) (2.25% IVM+1.25% ABM), 4% IVM, 3.15% IVM and placebo. For the evaluation of FECs and weight gain of the animals, individual samples were collected seven days before treatment and, +14, +30, +56, +91 and +118 days post-treatment (DPT). The efficacies in the 14th DPT were: 72.3% (1% MOX), 22.1% (4% IVM), 22% (2.25% IVM + 1.25% ABM) and 0% (3.15% ivermectin). 1% MOX was the only treatment that resulted in a significant increase in weight gain of the animals compared to the placebo group after 118 days of treatment, with a difference of 7.6 kg. Therefore, MOX remains a viable alternative for the control of helminths resistant to avermectins and still capable of resulting in significant productive gains, even with an efficacy below 95%.
Mortality caused by gastrointestinal nematodes in beef cattle submitted to an inadequate sanitary protocol Stephanie C. Lima, Dyego G.L. Borges, Rayane C. Pupin, Carolina C. Guizelini, Juliana P.L. Paula, Fernando A. Borges, Ricardo A.A. Lemos Pesquisa Veterinaria Brasileira, 2022 The aim of this study was to describe the epidemiological, clinical, and pathological findings of two outbreaks of gastrointestinal nematode infections in beef cattle kept under an inadequate sanitary protocol. An outbreak of trichostrongylosis occurred in Amambai, Mato Grosso do Sul (MS), from May to July 2016. The herd consisted of 3,000 Nellore cows, and of these, fifteen died after showing emaciation and diarrhea and remaining in recumbency. At necropsy, the abomasum showed edema in the folds, white, raised areas, multifocal to coalescent, and small ulcers. Histopathology showed larvae compatible with trichostrongylid nematodes were present inside the abomasum glands. Trichostrongylus axei was identify in the abomasum. The hemonchosis outbreak began in October 2018, in a breeding and finishing property in Santa Rita do Pardo, MS. Of 4,000 cattle aged 8 to 18 months, 673 became ill and 117 died. Clinical signs were emaciation, weakness, dehydration, submandibular edema, and soft stools. At necropsy, large numbers of nematodes were found in the abomasum; they were morphologically classified as Haemonchus placei. Both outbreaks were caused by failures in the parasite control protocol. However, in Outbreak I, frost and immune stress caused by lack of food may have contributed to the deaths. In Outbreak I, the main failure in the devermination protocol was the use of anthelmintics without carrying out an efficacy test. In Outbreak II, there was no parasite control protocol in the rearing and finishing property, and in the breeding property, there was resistance to the anthelmintic used (ivermectin). The two outbreaks highlight the importance of gastrointestinal nematode control protocols in cattle and demonstrate that infections by T. axei and H. placei can be lethal for this species.
Poisoning of calves reared with cows treated with abamectin Dyego Gonçalves Lino Borges, Fernando de Almeida Borges, Matheus Coura Vieira, Rayane Chitolina Pupin, Marcelo Augusto de Araújo, Carolina de Castro Guizelini, Ricardo Antônio Amaral de Lemos Toxicon, 2021
Effects of supplementation on production and age anticipation at first mating of ewe lambs in tropical pastures Thais Fernanda Farias de Souza Arco, Camila Celeste Brandão Ferreira Ítavo, Luís Carlos Vinhas Ítavo, Maria Inês Lenz Souza, Alexandre Menezes Dias, Gelson dos Santos Difante, Eliane Vianna da Costa e Silva, Fernando de Almeida Borges, Dyego Gonçalves Lino Borges, Kedma Leonora da Silva Monteiro Ferelli, Bruna Junqueira Rodrigues, Aline Aparecida da Silva Miguel, Camila de Godoy, Evelyn Silva de Melo Soares Tropical Animal Health and Production, 2021
Combination of quercetin and ivermectin: In vitro and in vivo effects against Haemonchus contortus Dyego Gonçalves Lino Borges, Marcelo Augusto de Araújo, Carlos Alexandre Carollo, Aline Regina Hellmann Carollo, Adrian Lifschitz, Mário Henrique Conde, Mariana Green de Freitas, Zelina dos Santos Freire, Juliane Francielle Tutija, Matheus Takemi Muchon Nakatani, Fernando de Almeida Borges Acta Tropica, 2020
Discovery of potential ovicidal natural products using metabolomics Dyego Gonçalves Lino Borges, Jessica Teles Echeverria, Tamires Lima de Oliveira, Rafael Pereira Heckler, Mariana Green de Freitas, Geraldo Alves Damasceno-Junior, Carlos Alexandre Carollo, Fernando de Almeida Borges Plos One, 2019
Eimeria species in dairy and beef cattle of different ages in Goiás state, Brazil Leonardo Bueno Cruvinel, João Eduardo Nicaretta, Thiago de Souza Azeredo Bastos, Luiz Fellipe Monteiro Couto, Jordana Belos dos Santos, Dina María Beltrán Zapa, Alliny Souza de Assis Cavalcante, Breno Cayeiro Cruz, Dyego Gonçalves Lino Borges, Fernando de Almeida Borges, Vando Edésio Soares, Welber Daniel Zanetti Lopes Revista Brasileira De Parasitologia Veterinaria, 2018
Efficacy of extracts from plants of the Brazilian Pantanal against Rhipicephalus (Boophilus) microplus Revista Brasileira De Parasitologia Veterinaria, 2013
