DR NG RAGHAVENDRA RAO

N. G. Raghavendra Rao, working as a Professor in the Department of Pharmacy, KIET School of Pharmacy, at KIET Group of institutions, Delhi-NCR, Ghaziabad, and Uttar Pradesh, I have 27 years of Teaching experience. He guided 3 PhD students and awarded, 63 M.Pharm students guided. He has Published 10 Indian patents and 08 Indian Design Patent Grant, 08 UK Design patent grants, and 04 Design patent grants are under process. Published 184 Research articles published in National and International journals and 6 Books/Book chapters published. Dr. NGR RAO have a keen interest in research activities as well and always believes in promoting the implementation of newer technological approaches on concept-based learning and teaching in my noble Pharmacy Profession.

EDUCATION

N. G. Raghavendra Rao, B.Pharm, M.Pharm, and Ph.D.

RESEARCH, TEACHING, or OTHER INTERESTS

Pharmacology, Toxicology and Pharmaceutics, General Pharmacology, Toxicology and Pharmaceutics, Drug Discovery, Pharmaceutical Science

Scopus Publications

Biomaterials in the Design of Nanosensors for Disease Diagnosis
N. G. Raghavendra Rao, Ashish Majumdar, Sheetal Mishra, Parag Jain, Akanksha Jain, et al.
Biomaterial Inspired Nanomedicines for Targeted Therapies, 2024
Trigonella foenum-Plantago Ovata Seeds Mucilage as a Superdisintegrants for the Development of Bisoprolol Fumarate Loaded Quick Dissolving Tablet (QDT)
Raghavendra Rao N G, Priyanka Gupta, Sheela M A
Research Journal of Pharmacy and Technology, 2023
Objective: The aim of this present research work, the aim was to develop drug-loaded Bisoprolol fumarate quick-dissolving tablets by direct compression method by using Trigonella Foenum - Plantago ovata seeds mucilage. Comparative studies between synthetic and natural superdisintegrants. Bisoprolol Fumarate is an antihypertensive drug incorporated in handling hypertension, and as a prophylaxis treatment of angina pectoris, heart failure. Methods: Bisoprolol fumarate-loaded tablets were developed, estimated for different pre and post-compressional parameters, FTIR study, and short-term stability studies. Results and Discussions: The FTIR spectral analysis results indicate no interaction between the drug and formulation additives. pre and post-compressional parameters were within the authorised Pharmacopeial limits, and the results were satisfactory. The disintegration time and dissolution investigations of formulations F12 and F15 were determined to be the most promising, with disintegration times of 22 and 24 secs, respectively. FormulationsF12 and F15 containing Trigonella Foenum and plantago ovata mucilage’s showed highest drug release above 99% within 20 and 25 min respectively. Trigonella Foenum mucilage and Plantago ovata was identified to be the better superdisintegrant compare to synthetic superdisintegrants. Stability studies to optimize the formulations were carried out for about 90 days. During the studies, no considerable changes were noticed in the compressed tablets for in-vitro disintegration time, hardness, friability and uniform distribution of drug content etc. Conclusion: Based on disintegration time the developed formulations F3, F12 and F15 were found to be mostly constitutive, with disintegration times of 30, 22, and 24 secs. The result outcome can be interpreted that the formulations loaded with Bisoprolol fumarate have shown enhanced dissolution rates that might have been the cause of improved bioavailability, subsequently an effective therapy by coupling with Trigonella foenum and Plantago ovata mucilage. These mucilages were plant-derived, non-toxic, bio-compatible, bio-degradable, and least side effects.
A review on various formulation methods in preparing Colon targeted mini-tablets for chronotherapy
M. A. Hadi, N. G. R. Rao, A. Rao, Tayyaba Mahtab, Sayeeda Tabassum
Journal of Applied Pharmaceutical Science, 2018
Rheumatoid arthritis disease, according to its circadian rhythms shows early morning peak symptoms. Sometimes, single unit (ex. larger tablets) and multiple units (ex. granules, pellets) colon targeted drug delivery systems are not always an efficient treatment option. Because single unit larger tablets may suffer from the disadvantages of unintentional disintegration of the formulation due to manufacturing deficiency or GI variation leading to complete dose dumping. Even the multiple unit drug delivery systems such as granules and pellets also have many drawbacks because of their irregular weights, shapes and sizes. Thus, a tight, reproducible in-vitro and in-vivo release profile canâ€™t be achieved. In an attempt to overcome the problems presented by these delivery systems, advanced system such as multiple unit mini-tablets have developed. This is an approach towards achieving critical factors such as better patient compliance and convenience. In this review, a concerted try has made to provide details of different formulation methods used in preparing mini-tablets of lornoxicam and naproxen drugs for colon targeted delivery in chronotherapy. The techniques formulated and evaluated as core-mini-tablets filled pulsincap drug delivery system (using time dependent polymers), matrix-mini-tablets filled capsule drug delivery system (using microsomal enzyme dependent and pH dependent polymers) and coated-mini-tablets filled capsule drug delivery system (using pH dependent polymers). All these methods were successful in targeting Anti-inflammatory drugs at colonic junction. Hence, the mentioned formulation methods can be successfully used in the chronotherapeutic treatment of Rheumatoid arthritis.
Design and development of simvastatin gas powered system for controlled release
N. G. Raghavendra Rao, N. G. Srivani, C. Kistayya
Research Journal of Pharmacy and Technology, 2016
Simvastatin is a Hypolipidemic used to control elevated cholesterol, or hypercholesterolemia. The primary uses of simvastatin are for the treatment of dyslipidemia and the prevention of cardiovascular disease. Gas powered Floating tablets of Simvastatin were developed by direct compression method using different grades of HPMC, Carbopol, ethyl cellulose, sodium CMC, sodium alginate, mixture of sodium bicarbonate, citric acid anhydrous as gas generating agents, Citric acid was also used as an antioxidant. The results of Pre-compressional parameters were within I.P prescribed limits. The prepared tablets were subjected to post compression analysis for the parameters such as hardness, friability, weight variation, thickness, diameter, drug content, lag time subsequently buoyancy time, and in-vitro dissolution studies. Tablets of all the formulation floated more than 12hrs. The results of in vitro buoyancy time and lag time study revealed that as the concentration of sodium bicarbonate increases there is increase in total buoyancy time and decrease in lag time. The results of dissolution study reveals that, a decrease in release rate of the drug was observed on increasing the polymer ratio and also by increasing the viscosity grades of the polymer. In all the formulations, hardness test indicated good mechanical strength, friability is less than 1%, indicated that tablets had a good mechanical resistance. DSC and FT-IR studies revealed that, there was no incompatibility of the drug with the excipients used. The stability study conducted as per the ICH guidelines and the formulations were found to be stable. From this study, it can be concluded that, the formulation retained for longer periods of time in the stomach and provides controlled release of the drug and may improved bioavailability.
Formulation and evaluation of valsartan fast disintegrating tablets by vacuum drying technique
Asian Journal of Pharmaceutical and Clinical Research, 2016
Acenocoumarol or warfarin: Which is the clinician’s ally?
Asian Journal of Pharmaceutical and Clinical Research, 2016
Formulation and evaluation of ileo-colonic targeted matrix-mini-tablets of Naproxen for chronotherapeutic treatment of rheumatoid arthritis
Mohd Abdul Hadi, N.G. Raghavendra Rao, A. Srinivasa Rao
Saudi Pharmaceutical Journal, 2016
Pharmacokinetic parameters determination and in vitro–in vivo correlation of ileocolonic-targeted pH-responsive coated mini-tablets of naproxen
Mohd Abdul Hadi
Scientia Pharmaceutica, 2015
This research work aims to determine the pharmacokinetic parameters and in vitro-in vivo correlation of the selected ileocolonic-targeted coated mini-tablet filled capsule formulation of naproxen. The pure suspension and coated mini-tablet filled capsule formulation of naproxen were administered to adult albino rabbits through the oral route. The samples were analyzed for naproxen by an HPLC method. For the pure drug suspension, the peak plasma concentration was found as 8.499±0.029 μg/ml at 1.139±0.010 hours and the half-life was found to be 9.459±0.387 hours, whereas for the formulation the peak plasma concentration was found as 6.814±0.037 μg/ml at 8.042±0.069 hours and the half-life was found to be 19.657±0.359 hours. This decreased the peak plasma concentration at a delayed time and increased the half-life of the capsule formulation in comparison with the pure drug suspension which showed that naproxen was only targeted to the ileocolonic region. A significant in vitro-in vivo correlation (i.e. R2=0.9901) was also obtained. Thus, the results of these findings suggest that naproxen formulated as coated mini-tablets can be suitable for targeted ileocolonic drug delivery.
Formulation and evaluation of mini-tablets-filled-pulsincap delivery of lornoxicam in the chronotherapeutic treatment of rheumatoid arthritis
Pakistan Journal of Pharmaceutical Sciences, 2015
Design and development of oral sustained release matrix tablets of didanosine
Asian Journal of Pharmaceutical and Clinical Research, 2014
Formulation and evaluation of fast dissolving tablets of Montelukast sodium using co-processed superdisintegrants
International Journal of Drug Development and Research, 2014
Formulation and evaluation of pH-responsive mini-tablets for ileo-colonic targeted drug delivery
MA Hadi, NGR Rao, AS Rao
Tropical Journal of Pharmaceutical Research, 2014
Matrix-mini-tablets of lornoxicam for targeting early morning peak symptoms of rheumatoid arthritis
Iranian Journal of Basic Medical Sciences, 2014
Formulation and evaluation of compression coated tablets of lornoxicam for targeting early morning peak symptoms of rheumatoid arthritis
Mohd Abdul Hadi, NG Raghavendra Rao, A Srinivasa Rao
Dhaka University Journal of Pharmaceutical Sciences, 2013
Design and development of oral sustained release matrix tablets of didanosine using natural polymer blend
Journal of Chemical and Pharmaceutical Research, 2013
Formulation and design of taste masked Quetiapine Fumarate orally fast disintegrating tablets
Asian Journal of Pharmaceutical and Clinical Research, 2013
Overview on buccal drug delivery systems
Journal of Pharmaceutical Sciences and Research, 2013
Impact of capsules as a carrier for multiple unit drug delivery and the importance of HPMC capsules
Research Journal of Pharmacy and Technology, 2013
Influence of pore-former on drug release from ethyl cellulose film coated mini-tablets
International Journal of Pharmaceutical Research, 2012
Development and evaluation of ropinirole mucoadhesive patches for buccal drug delivery
Drug Invention Today, 2012
Formulation and evaluation of mucoadhesive buccal bilayered tablets of salbutamol
International Journal of Drug Development and Research, 2012
Formulation and evaluation of biphasic drug delivery system of terbutaline sulphate for chronotherapy
International Journal of Pharma and Bio Sciences, 2012
Formulation and evaluation of fast dissolving granisetron hydrochloride tablets: Effect of functionality of superdisintegrants
Pharma Research, 2011
Formulation and evaluation of fast dissolving Granisetron hydrochloride tablets: Effect of functionality of superdisintegrants
International Journal of Advances in Pharmaceutical Sciences, 2011
Design and development of fast dissolving Cinnarizine tablets by sublimation technique
Research Journal of Pharmacy and Technology, 2011
Design and characterization of gas powered system of Zidovudine using synthetic polymers
International Journal of Pharma and Bio Sciences, 2011
Formulation and evaluation of fast dissolving tablets of granisetron hydrochloride by vacuum drying technique
Journal of Applied Pharmaceutical Science, 2011
Design of fast dissolving tablets of Metoprolol tartrate using novel co-processed superdisintegrants
International Journal of Pharmaceutical Sciences Review and Research, 2011
Fabrication and evaluation of fast dissolving tablets of Tizanidine hydrochloride by solid dispersion technique
International Journal of Pharmaceutical Sciences Review and Research, 2011
Design and development of mucoadhesive drug delivery system of zolmitriptan
International Journal of Pharmacy and Technology, 2011
Development and evaluation of tablets-filled-capsule system for chronotherapeutic delivery of montelukast sodium
International Journal of Pharmacy and Technology, 2011
Formulation and evaluation of montelukast sodium mucoadhesive buccal patches for chronic asthma attacks
International Journal of Pharma and Bio Sciences, 2010
Formulation and evaluation of gas powered systems of cefixime tablets for controlled release
International Journal of Pharma and Bio Sciences, 2010
Formulation and evaluation of mouth dissolving tablets of metoprolol tartrate by sublimation method
International Journal of Pharma and Bio Sciences, 2010
Formulation and in vitro evaluation of gastric oral floating tablets of cefixime for controlled release
Research Journal of Pharmaceutical Biological and Chemical Sciences, 2010
Comparative study on effect of diferent techniques used in the formulation of felodipine fast dissolving tablets
International Journal of Pharmacy and Pharmaceutical Sciences, 2010
Formulation and evaluation of fast dissolving tablets of carbamazepine using natural superdisintegrant plantago ovata seed powder and mucilage
International Journal of Pharmacy and Pharmaceutical Sciences, 2010
Development of carbamazepine fast dissolving tablets: Effect of functionality of hydrophillic carriers on solid dispersion technique
Asian Journal of Pharmaceutical and Clinical Research, 2010
Formulation, evaluation and anti-inflammatory activity of topical etoricoxib gel
Asian Journal of Pharmaceutical and Clinical Research, 2010
Comparative study on effect of different techniques used in the development of chlorthalidone fast dissolving tablets
Research Journal of Pharmaceutical Biological and Chemical Sciences, 2010
Preparation and characterization of mucoadhesive microcapsules of salbutamol sulfate
RaghavendraN.G Rao, Doddayya Hiremath, Pradnya Patil
Asian Journal of Pharmaceutics, 2010
Formulation and evaluation of sustained release matrix tablets of tramadol hydrochloride
International Journal of Pharmacy and Pharmaceutical Sciences, 2009
Formulation and evaluation of fast dissolving chlorthalidone tablets
International Journal of Pharmacy and Pharmaceutical Sciences, 2009
Development and evaluation of carbamazepine fast dissolving tablets prepared with a complex by direct compression technique
NG Raghavendra Rao, T Patel, S Gandhi
Asian Journal of Pharmaceutics, 2009
Clinical studies and antimicrobial activity of ciprofloxacin hydrochloride medicated dental gels for periodontal infection
NG Raghavendra Rao, KPurushotham Rao, S Muthalik, A Shivanand
Asian Journal of Pharmaceutics, 2009

RECENT SCHOLAR PUBLICATIONS

Development of a Novel Quercetin Phytosome-based Topical Hydrogel for Anti-Inflammatory and Antioxidant Effects in Psoriasis
NGR Rao
journal of Neonatal surgery 14 (7), 593-601 , 2025
2025
AI-assisted formulation design for improved drug delivery and bioavailability
S Tyagi, A Pathak, NR Rao, S Nehra, A Asthana, V Sharma, G Katyal, ...
Pak. Heart J 56, 149-162 , 2023
2023
Citations: 12
Applications of Nanomaterials In Improving The Traditional Diagnostic Approach
J Chaudhary, A Tyagi, S Bhatt, A Pathak, NGR Rao, S Mittal
Journal of Survey in Fisheries Sciences 9 (1), 191-206 , 2022
2022
Citations: 2
Formulation and Evaluation of Gastroretentive Effervescent Floating Drug Delivery System of Zidovudine.
NG Raghavendra Rao, S Firangi, K Patel
vitro 1, 226-233 , 2021
2021
Citations: 4
Synthesis and In-Vivo Activity Of Novel Antihypertensive Agent Based On Pyridazine Scaffold.
NGRR Vikas Jakhmola, Sunil Jawla, Ravinesh Mishra
International Journal of Pharmaceutical Sciences and Research 12 (1), 1000-11 , 2021
2021
Market performance and sales analysis of captopril in Vikasnagar region.
NGRR Manisha Tomar, Pranshu Tangri, Sushil Singhal
International Research Journal of Modernization in Engineering, Technology … , 2020
2020
Analysis of market performance of various brands of Ofloxacin in almora region.
NGRRA Himanshu Dhulia, Pranshu Tangri, Sushil Singhal
International Research Journal of Modernization in Engineering, Technology … , 2020
2020
Design and Evaluation of Guaifenesin Matrix Type Lozenges Using Herbal and Synthetic Polymer Blends.
SV Pranshu Tangri, NG Raghavendra Rao, Akshaya Chauhan, Piyush Chauhan ...
International Journal of Scientific Research and Engineering Development. 3 … , 2020
2020
. Formulation and Evaluation of Mouth dissolving tablet of Zafirlukast using directly compressible excipients: a Review.
RRMR Vikash Jakhmola, N.G. Raghavendra Rao
International Journal of Research and Analytical Reviews 7 (2), 189-193 , 2020
2020
Formulation and Evaluation of Ketoconazole Polymeric Films for Topical Application
P Tripathi, Y Tyagi, NGR Rao
Indian Journal of Research in Pharmacy and Biotechnology (IJRPB) 8 (3) , 2020
2020
Formulation And Evaluation Of Lafutidine Loaded Fast Dissolving Tablet Using Trigonella Foenum
LKS Teli, Y Tyagi, NR Rao
Indian Journal of Research in Pharmacy and Biotechnology (IJRPB) 8 (3), 1-9 , 2020
2020
Citations: 1
A Comparative Study of Different Marketed Formulations of Albendazole
NGR Rao, Y Tyagi, S Sidola
World Journal of Pharmaceutical Research 9 (6), 736-759 , 2020
2020
Citations: 5
TO EVALUATE THE ROLE OF HERBAL DRUGS IN THE MANAGEMENT OF PSORIASIS: A REVIEW ARTICLE
L Siddiqui, Y Tyagi, NGR Rao
2020
An advance review on salicylic acid ointment for treatment of acne
A Kotiyal, Y Tyagi, NR Rao
World J. Pharm. Res 9 (5), 1940-1949 , 2020
2020
Citations: 2
An application of natural sources in formulating Ketoconazole loaded micro dispersion gel.
MK N. G. Raghavendra Rao, Yogita Tyagi
Indian Journal of Research in Pharmacy and Biotechnology 8 (2), 1-18 , 2020
2020
Formulation and Evaluation of Tinidazole Loaded Fast Dissolving Tablets.
SV Pranshu Tangri, N.G. Raghavendra Rao, Akshaya Chauhan, Piyush Chauhan ...
International Research Journal of Engineering and Technology 7 (3), 4318-4322 , 2020
2020
Design and Evaluation of Albendazole Sustained Release Tablets.
SV Pranshu Tangri, N. G. Raghavendra Rao, Akshaya Chauhan, Piyush Chauhan ...
International Research Journal of Engineering and Technology 7 (3), 4310-4317 , 2020
2020
AN APPLICATION OF NATURAL SOURCES IN FORMULATING KETOCONAZOLE LOADED MICRO DISPERSION GEL
NGR Rao, Y Tyagi, M Kesari
Indian Journal of Research in Pharmacy and Biotechnology (IJRPB) 8 (2) , 2020
2020
In-vitro bioequivalence study between four different marketed formulations of gliclazide with sustained release metformin hydrochloride tablet as an anti
J Chauhan, P Giri, Y Chandola, P Tangari, N Guggilla, R Rao
Diabetic Drug 9, 1239-48 , 2020
2020
Citations: 1
Formulation and Evaluation of Mouth dissolving tablet of Zafirlukast using directly compressible excipients
RRMR Vikash Jakhmola, N.G. Raghavendra Rao
International Journal of Research and Analytical Reviews7 7 (2), 189-193 , 2020
2020

MOST CITED SCHOLAR PUBLICATIONS

Overview on controlled release dosage form
S Ummadi, B Shravani, NGR Rao, MS Reddy, B Sanjeev
System 7 (8), 51-60 , 2013
2013
Citations: 193
Overview on buccal drug delivery systems
NGR Rao, B Shravani, MS Reddy
Journal of pharmaceutical sciences and research 5 (4), 80 , 2013
2013
Citations: 104
Formulation, evaluation and anti-inflammatory activity of topical etoricoxib gel
PR Prakash, NGR Rao, S Chowdary
Asian J Pharm Clin Res 3 (2), 126-129 , 2010
2010
Citations: 68
Formulation and evaluation of sustained release matrix tablets of tramadol hydrochloride
RN Raghavendra, S Gandhi, T Patel
Int. J. Phar. & Phar. Sci 1 (1), 60-69 , 2009
2009
Citations: 67
Overview on fast dissolving oral films
N Khatoon, NGR Rao, BM Reddy
International journal of Chemistry and Pharmaceutical sciences 1 (1), 63-75 , 2013
2013
Citations: 63
Review on Matrix Tablet as Sustained Release.
NG Rao, K Raj, BS Nayak
International Journal of Pharmaceutical Research & Allied Sciences 2 (3) , 2013
2013
Citations: 46
Development and evaluation of carbamazepine fast dissolving tablets prepared with a complex by direct compression technique
NGR Rao, T Patel, S Gandhi
Asian Journal of Pharmaceutics (AJP) 3 (2) , 2009
2009
Citations: 45
Formulation and evaluation of ileo-colonic targeted matrix-mini-tablets of Naproxen for chronotherapeutic treatment of rheumatoid arthritis
MA Hadi, NGR Rao, AS Rao
Saudi pharmaceutical journal 24 (1), 64-73 , 2016
2016
Citations: 43
Formulation and evaluation of mini-tablets-filled-pulsincap delivery of lornoxicam in the chronotherapeutic treatment of rheumatoid arthritis.
MA Hadi, NG Raghavendra Rao, AS Rao
Pakistan journal of pharmaceutical sciences 28 (1) , 2015
2015
Citations: 43
MUCOADHESIVE BUCCAL PATCHES FOR CHRONIC ASTHMA ATTACKS.
R RAGHAVENDRA, VB Suryakar
International journal of Pharma and Bio sciences 1, 2 , 2010
2010
Citations: 36
Formulation and evaluation of oral fast dissolving films of montelukast sodium
N Khatoon, NGR Rao, BM Reddy
International Journal Of Pharmaceutical Sciences And Research 5 (5), 1780 , 2014
2014
Citations: 35
A Novel approach to sustained Montelukast sodium release: Differentially coated mini-tablets in HPMC capsules
NGR Rao, MA Hadi, HA Panchal
International Journal of Pharmaceutical and Biomedical Sciences 2 (2), 90-97 , 2011
2011
Citations: 33
Formulation and evaluation of zero order release glipizide bilayer matrix tablets using natural and synthetic polymers
NGR Rao, A Yadav, U Kulkarni
Int J Curr Pharm Res 2, 34-42 , 2010
2010
Citations: 30
Preparation and characterization of ionotropic cross-linked chitosan microparticles for controlled release of aceclofenac
NGR Rao, U Kulkarni, A Deshmukh, DK Suresh
Int J Pharm Sci Drug Res 2 (2), 107-111 , 2010
2010
Citations: 28
Formulation and evaluation of fast dissolving chlorthalidone tablets
R RAGHAVENDRA, RK Kota, CM Setty, R PURUSHOTHAM
International journal of pharmacy and pharmaceutical sciences 1 (1), 79-87 , 2009
2009
Citations: 28
Formulation and Evaluation of pH-Responsive Mini-Tablets for Ileo-Colonic Targeted Drug Delivery.
MA Hadi, NG Rao, AS Rao
Tropical Journal of Pharmaceutical Research 13 (7) , 2014
2014
Citations: 27
A review on pulsatile drug delivery system
NGR Rao, P Soumya, K Revathi, BS Nayak
Int Res J Pharm 4 (3), 31-44 , 2013
2013
Citations: 27
Mini-tablets technology: an overview
MA Hadi, NGR Rao, S Firangi
Am J PharmTech Res 2, 128-150 , 2012
2012
Citations: 26
Design and development of aceclofenac fast dissolving tablets by amorphous solid dispersion technique using modified aeglemarmelos gum
U Kulkarni, NG Raghavendra Rao
Ijprd 3 (2), 201-210 , 2011
2011
Citations: 26
Buccal patch as drug delivery system: An overview
R Neelagiri, M Reddy, N Rao
Int J Curr Pharm Res 5 (2), 40-7 , 2013
2013
Citations: 22

Publications

Published 184 Research articles published in National and International journals. Out of which 45 Scopus and SCI indexed Journals.

RESEARCH OUTPUTS (PATENTS, SOFTWARE, PUBLICATIONS, PRODUCTS)

Published 10 Indian patents and 08 Indian Design Patent Grant, 08 UK Design patent grants, and 04 Design patent grants are under process.