Dr. Baburao N Chandakavathe

@pharmacycol.com

Assistant professor
D.S..T.S mandals college of pharmacy, solapur

Dr. Baburao N Chandakavathe


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https://researchid.co/babu41126
Profile Summary
Dr. Baburao N. Chandakavathe Assistant Professor at D.S.T.S. Mandal’s College of Pharmacy, Jule Solapur, Solapur. He completed his graduation and post graduation degree from Rajiv Gandhi University of Health Sciences, Karnataka, Bangalore. Mr. Baburao, qualified GATE and received several scholarships and awards during his studies. His research interests are Polymeric science, Extraction and formulation of herbal preparations, Novel Drug Delivery Systems. He is serving as Editorial Board Member and Reviewer for many reputed national and international journals. Mr. Baburao, has more than 10 years of teaching and research experience. Mr. Baburao, has presented scientific posters in national and international workshops/conferences. There are 12 publications in national and international journals with good impact factor.
Teaching Experience
UG Teaching Experience: 10 Years (Subject Taught: Pharmaceutics-I, Industrial Pharmacy-I)
PG subject taught: Advanced Pharmaceutics

EDUCATION

M. Pharm. Pharmaceutics from RGUHS Bangaluru
PhD from P A H Solapur University, Solapur, India

RESEARCH INTERESTS

Herbs
Natural polymers
Grafting of natural polymers
Drug delivery system
Dosage forms
11

Scopus Publications

292

Scholar Citations

8

Scholar h-index

7

Scholar i10-index

Scopus Publications

  • Fabrication of Sustainable Modified Fenugreek Gum Block Copolymer in Oral Controlled Drug Delivery System: Synthesis, Toxicity, in Vitro and in Vivo Pharmacokinetics
    Baburao N. Chandakavathe, Raghavendra Kulkarni, Ashwin Mali, Amol Muthal, Vaibhav Shinde, Ravindra Kulkarni
    Journal of Pharmaceutical Innovation, 2025
  • Synthesis and Assessment of Acrylamide-graft-mesquite gum polymer (Aam-g-MG) for its Biodegradability in E. coli and Toxicity in Drosophila melanogaster
    Baburao N. Chandakavathe, Ravindra Kulkarni
    Research Journal of Pharmacy and Technology, 2024
    Aim of the present investigation was to develop a novel, non-toxic and biodegradable copolymer of acrylamide-graft-mesquite gum polymer (Aam-g-MGP) by graft copolymerisation technique using cerric ammonium nitrate as free radical initiator under microwave conditions. The mesquite raw gum was purified and and grafted with acrylamide using ceric ammonium nitrate as a free radical initiator. The variation in reaction parameters affected the percent grafting (%G) and grafting efficiency (%GE) of the copolymer samples. The grafting was confirmed by FT-IR and elemental analysis, FT-IR spectral studies and elemental analysis data supported the grafting process. Subsequently synthesised graft copolymer was subjected for viscosity, water retention, swelling index and hydration capacity evaluation. Modified polymer was also tested for biodegradability on E. coli, and toxicity in Drosophila melanogaster. The developed copolymer demonstrated considerably increase in viscosity, water retention capacity, swelling index, and hydration capacity as compared to ungrafted mesquite gum polymer. The grafted copolymer Aam-g-MGP was proved biodegradable and non-toxic in nature. Based on the results swelling index and water retention capacity developed copolymer can be used in the development of extended release pharmaceutical formulations.
  • Development of Colon Targeted Extended Drug Delivery System for Mebendazole Using Grafted Natural Polymers
    Baburao Nanasaheb Chandakavathe, Ravindra Kulkarni, Akash Dadanna Rajmane, Snehal Limbraj Mane, Nishigandha Jayant Waykule
    Indian Journal of Pharmaceutical Education and Research, 2024
    Background: Even though the natural polymers are biodegradable, non-toxic and cost effective, but these suffer with some of drawbacks like uncontrolled drug release, enzymatic degradation, reduction in viscosity on long term storage, thermal instability etc. The aforesaid limitations can be overcome by grafting of natural polymers to obtain high performance biomaterials for drug delivery system. Materials and Methods: Purified fenugreek and mesquite gums were grafted with acrylamide using Ceric Ammonium Nitrate (CAN) as free radical initiator. Confirmation of grafting was done by elemental analysis and FT-IR spectroscopy. Grafted copolymers were tested for its biodegradability in microorganisms and toxicity in Drosophila melanogaster . Nine batches of mebendazole tablets (F1 to F9) were prepared using mixture of acrylamide grafted fenugreek and mesquite gum polymer by 3 2 factorial designs. Compressed tablets were tested for post-compression compendia parameters. Results: FT-IR confirmed the grafting and compatibility between drug and synthesized copolymers. Synthesised graft copolymers showed significant swelling index, water retention capacity, viscosity, hydration capacity than the pure gum polymers. Compressed tablets showed hardness (5.5 to 6.6 kg/cm 2 ), friability (less than 1%). thickness (3 mm) and complied weight variation test as per compendial standards. Further tablets were coated with Eudragit RS 100 demonstrated small amount of drug release in 5 hr and maximum amount of drug released in colonic region. Hence, after reaching colonic region drug release extended upto 12 hr due to satisfactory drug release by copolymers. Conclusion: Grafted copolymers were biodegradable, non-toxic and showed higher swelling index then pure polymers. These copolymers can be used as drug release retardant in the tablet formulation.
  • Formulation and Assessment of In Vitro Antimicrobial Activity of Herbal Toothpaste
    Baburao N. Chandakavathe, Ravindra G. Kulkarni, Shivsharan B. Dhadde
    Proceedings of the National Academy of Sciences India Section B Biological Sciences, 2023
  • Grafting of Natural Polymers and Gums for Drug Delivery Applications: A Perspective Review
    Baburao N. Chandakavathe, Ravindra G. Kulkarni, Shivsharan B. Dhadde
    Critical Reviews in Therapeutic Drug Carrier Systems, 2022
    Natural polymers have received more attention because of their advantages over synthetic polymers such as abundant availability, low cost, biodegradability and non-toxicity. However, natural polymers suffer some limitations such as drop-in viscosity upon storage, uncontrolled hydration, solubility, inability to perform under high temperature and pressure (thermal stability), etc. In many instances above mentioned drawbacks of natural polymers limits their applications in drug delivery systems. Grafting of natural polymer leads to improved properties and characteristics of backbones of macromolecules such as improvement in gel strength, swelling index, mucoadhesion, drug targeting and drug release profile. Therefore, in recent decades grafting of the natural polymer has gained immense importance for the development of drug delivery systems. In addition to the pharmaceutical applications graft copolymers are extensively utilized in diversified fields. The present review is an attempt to define the grafting, various methods of polymer grafting and their application in drug delivery.
  • Relevance of nanotechnology in solving oral drug delivery challenges: A perspective review
    Shivsharan B. Dhadde, Jagadevappa S. Patil, Baburao N. Chandakavathe, B. S. Thippeswamy, Mahantesh G. Kavatekar
    Critical Reviews in Therapeutic Drug Carrier Systems, 2020
    Nanotechnology is opening up new opportunities in drug delivery, including oral delivery, and it may reduce toxicity and increase drug ability. Presently, researchers are expanding their knowledge in the development of oral nanomedicine to extend the scope of oral drug delivery and exhibit excellent platforms for drug transportation, target, and controlled release. The present review is an attempt to define updated oral nanostructured systems for the delivery of a wide range of drugs. The review also focuses on the use of different polymeric and other materials, technologies adopted, and benefits/drawbacks of delivery systems.
  • Assessment of Toothpaste Formulations Containing Turmeric and Neem Extract for Prevention of Dental Caries and Periodontal Diseases
    Baburao N. Chandakavathe, Deepak K. Deshpande, P. V. Swamy, Shivsharan B. Dhadde
    Proceedings of the National Academy of Sciences India Section B Biological Sciences, 2018
  • Nanostructure Drug Delivery System Is an Option to Solve Antimicrobial Drug Resistance: Perspective Review. Perspective Review.
    Jagadevappa S. Patil, Shivsharan B. Dhadde, Baburao N. Chandakavathe
    Characterization and Biology of Nanomaterials for Drug Delivery Nanoscience and Nanotechnology in Drug Delivery, 2018
  • Embelin Ameliorate Testosterone-Induced Prostatic Hyperplasia in Rats
    Marulasiddeshwara Roopesh, S. R. Anand Kumar, Shivsharan B. Dhadde, B. S. Thippeswamy, Veeresh P. Veerapur, S. Badami, N. C. K. Baburao
    Proceedings of the National Academy of Sciences India Section B Biological Sciences, 2018
  • Ameliorative effect of chromium-D-phenylalanine complex on indomethacin-induced inflammatory bowel disease in rats
    S. Nagarjun, Shivsharan B. Dhadde, Veeresh P. Veerapur, B.S. Thippeswamy, Baburao N. Chandakavathe
    Biomedicine and Pharmacotherapy, 2017
  • Immunomodulatory effect of decalepis hamiltonii wight and arn roots extract on rodents
    Sunitha T G Sunitha, Shivsharan B. Dhadde, Sharanbasappa Durg, Syed Mansoor Ahmed, B.S. Thippeswamy, et al.
    Indian Journal of Pharmaceutical Education and Research, 2016

RECENT SCHOLAR PUBLICATIONS

  • Concentration of propolis as a storage medium for avulsed teeth: a systematic review
    C Chhabra, KG Chhabra, S Thangeswaran, S Shere
    Frontiers in medicine 12, 1583113 , 2025
    2025
    Citations: 1
  • Fabrication of sustainable modified fenugreek gum block copolymer in oral controlled drug delivery system: synthesis, toxicity, in vitro and in vivo pharmacokinetics
    BN Chandakavathe, R Kulkarni, A Mali, A Muthal, V Shinde, R Kulkarni
    Journal of Pharmaceutical Innovation 20 (4), 151 , 2025
    2025
    Citations: 1
  • A Polyherbal Approach to Hair Care: Development and Evaluation of a Solid Shampoo Bar
    R S Pawar, BN Chandakavathe
    International Journal of Innovative Science and Research Technology 10 (6 … , 2025
    2025
    Citations: 2
  • Effects of pomegranate extract on preventing dental caries: a systematic review
    N Rafeie, Y Salimi, ZS Aghamir, A Amini, H Taheri, S Sadreddini, ...
    Frontiers in Oral Health 6, 1484364 , 2025
    2025
    Citations: 2
  • Development of colon targeted extended drug delivery system for mebendazole using grafted natural polymers
    BN Chandakavathe, R Kulkarni, AD Rajmane, SL Mane, NJ Waykule
    Indian J Pharm Educ Res 58 (3s), s837-s847 , 2024
    2024
    Citations: 5
  • Synthesis and Assessment of Acrylamide-graft-mesquite gum polymer (Aam-g-MG) for its Biodegradability in E. coli and Toxicity in Drosophila melanogaster
    BN Chandakavathe, R Kulkarni
    Research Journal of Pharmacy and Technology 17 (11), 5555-5560 , 2024
    2024
    Citations: 1
  • Formulation and assessment of in vitro antimicrobial activity of herbal toothpaste
    BN Chandakavathe, RG Kulkarni, SB Dhadde
    Proceedings of the National Academy of Sciences, India Section B: Biological … , 2023
    2023
    Citations: 8
  • Grafting of natural polymers and gums for drug delivery applications: A perspective review
    BN Chandakavathe, RG Kulkarni, SB Dhadde
    Critical Reviews™ in Therapeutic Drug Carrier Systems 39 (6) , 2022
    2022
    Citations: 14
  • Relevance of nanotechnology in solving oral drug delivery challenges: A perspective review
    SB Dhadde, JS Patil, BN Chandakavathe, BS Thippeswamy, ...
    Critical Reviews™ in Therapeutic Drug Carrier Systems 37 (5) , 2020
    2020
    Citations: 10
  • Characterization and Biology of Nanomaterials for Drug Delivery
    JS Patil, SB Dhadde, BN Chandakavathe
    Elsevier , 2019
    2019
    Citations: 3
  • Textbook of Industrial Pharmacy
    BNCSB Dhadde
    Studium press New Delhi 1, 523 , 2019
    2019
  • Nanostructure drug delivery system is an option to solve antimicrobial drug resistance: perspective review
    JS Patil, SB Dhadde, BN Chandakavathe
    Characterization and Biology of Nanomaterials for Drug Delivery, 165-197 , 2019
    2019
    Citations: 11
  • Assessment of toothpaste formulations containing turmeric and neem extract for prevention of dental caries and periodontal diseases
    BN Chandakavathe, DK Deshpande, PV Swamy, SB Dhadde
    Proceedings of the National Academy of Sciences, India Section B: Biological … , 2018
    2018
    Citations: 9
  • Characterization and biology of nanomaterials for drug delivery: nanoscience and nanotechnology in drug delivery
    S Mohapatra, S Ranjan, N Dasgupta, S Thomas, RK Mishra
    Elsevier , 2018
    2018
    Citations: 51
  • Embelin ameliorate testosterone-induced prostatic hyperplasia in rats
    M Roopesh, SR Anand Kumar, SB Dhadde, BS Thippeswamy, ...
    Proceedings of the National Academy of Sciences, India Section B: Biological … , 2018
    2018
    Citations: 1
  • Embelin ameliorate testosterone-induced prostatic hyperplasia in rats.
    MR Marulasiddeshwara Roopesh, SRA Kumar, SB Dhadde, ...
    2018
  • Anti-diabetic Potential of Flavonoids and Their Molecular Mechanisms – A Review
    BNC Shivsharan B. Dhadde
    Recent Advances in the Molecular Mechanism of Flavonoids 1 (1), 104-139 , 2017
    2017
  • Ameliorative effect of chromium-d-phenylalanine complex on indomethacin-induced inflammatory bowel disease in rats
    S Nagarjun, SB Dhadde, VP Veerapur, BS Thippeswamy, ...
    Biomedicine & Pharmacotherapy 89, 1061-1066 , 2017
    2017
    Citations: 56
  • Indian Journal of Novel Drug Delivery
    SM GHURGHURE, BN CHANDAKAVATHE
    Indian Journal of Novel Drug delivery 8 (2), 93-99 , 2016
    2016
  • Effect of embelin against 3-nitropropionic acid-induced Huntington's disease in rats
    SB Dhadde, P Nagakannan, M Roopesh, SRA Kumar, BS Thippeswamy, ...
    Biomedicine & Pharmacotherapy 77, 52-58 , 2016
    2016
    Citations: 95

MOST CITED SCHOLAR PUBLICATIONS

  • Effect of embelin against 3-nitropropionic acid-induced Huntington's disease in rats
    SB Dhadde, P Nagakannan, M Roopesh, SRA Kumar, BS Thippeswamy, ...
    Biomedicine & Pharmacotherapy 77, 52-58 , 2016
    2016
    Citations: 95
  • Ameliorative effect of chromium-d-phenylalanine complex on indomethacin-induced inflammatory bowel disease in rats
    S Nagarjun, SB Dhadde, VP Veerapur, BS Thippeswamy, ...
    Biomedicine & Pharmacotherapy 89, 1061-1066 , 2017
    2017
    Citations: 56
  • Characterization and biology of nanomaterials for drug delivery: nanoscience and nanotechnology in drug delivery
    S Mohapatra, S Ranjan, N Dasgupta, S Thomas, RK Mishra
    Elsevier , 2018
    2018
    Citations: 51
  • Formulation and evaluation of anti-asthmatic theophylline tablet lozenges
    RK Purushotham, KC Ashok, AKB Afshanlaheji, P Manjunath, ...
    Int J Pharm Sci 3 (1), 125-8 , 2011
    2011
    Citations: 16
  • Grafting of natural polymers and gums for drug delivery applications: A perspective review
    BN Chandakavathe, RG Kulkarni, SB Dhadde
    Critical Reviews™ in Therapeutic Drug Carrier Systems 39 (6) , 2022
    2022
    Citations: 14
  • Nanostructure drug delivery system is an option to solve antimicrobial drug resistance: perspective review
    JS Patil, SB Dhadde, BN Chandakavathe
    Characterization and Biology of Nanomaterials for Drug Delivery, 165-197 , 2019
    2019
    Citations: 11
  • Relevance of nanotechnology in solving oral drug delivery challenges: A perspective review
    SB Dhadde, JS Patil, BN Chandakavathe, BS Thippeswamy, ...
    Critical Reviews™ in Therapeutic Drug Carrier Systems 37 (5) , 2020
    2020
    Citations: 10
  • Assessment of toothpaste formulations containing turmeric and neem extract for prevention of dental caries and periodontal diseases
    BN Chandakavathe, DK Deshpande, PV Swamy, SB Dhadde
    Proceedings of the National Academy of Sciences, India Section B: Biological … , 2018
    2018
    Citations: 9
  • Formulation and assessment of in vitro antimicrobial activity of herbal toothpaste
    BN Chandakavathe, RG Kulkarni, SB Dhadde
    Proceedings of the National Academy of Sciences, India Section B: Biological … , 2023
    2023
    Citations: 8
  • Design and Development of Spherical Agglomerates of Drug for the Enhancement of Solubility
    BNSM Ghurghure
    Indian Journal of Novel Drug Delivery 8 (2), 93-99 , 2016
    2016
    Citations: 6
  • Development of colon targeted extended drug delivery system for mebendazole using grafted natural polymers
    BN Chandakavathe, R Kulkarni, AD Rajmane, SL Mane, NJ Waykule
    Indian J Pharm Educ Res 58 (3s), s837-s847 , 2024
    2024
    Citations: 5
  • Characterization and Biology of Nanomaterials for Drug Delivery
    JS Patil, SB Dhadde, BN Chandakavathe
    Elsevier , 2019
    2019
    Citations: 3
  • A Polyherbal Approach to Hair Care: Development and Evaluation of a Solid Shampoo Bar
    R S Pawar, BN Chandakavathe
    International Journal of Innovative Science and Research Technology 10 (6 … , 2025
    2025
    Citations: 2
  • Effects of pomegranate extract on preventing dental caries: a systematic review
    N Rafeie, Y Salimi, ZS Aghamir, A Amini, H Taheri, S Sadreddini, ...
    Frontiers in Oral Health 6, 1484364 , 2025
    2025
    Citations: 2
  • Concentration of propolis as a storage medium for avulsed teeth: a systematic review
    C Chhabra, KG Chhabra, S Thangeswaran, S Shere
    Frontiers in medicine 12, 1583113 , 2025
    2025
    Citations: 1
  • Fabrication of sustainable modified fenugreek gum block copolymer in oral controlled drug delivery system: synthesis, toxicity, in vitro and in vivo pharmacokinetics
    BN Chandakavathe, R Kulkarni, A Mali, A Muthal, V Shinde, R Kulkarni
    Journal of Pharmaceutical Innovation 20 (4), 151 , 2025
    2025
    Citations: 1
  • Synthesis and Assessment of Acrylamide-graft-mesquite gum polymer (Aam-g-MG) for its Biodegradability in E. coli and Toxicity in Drosophila melanogaster
    BN Chandakavathe, R Kulkarni
    Research Journal of Pharmacy and Technology 17 (11), 5555-5560 , 2024
    2024
    Citations: 1
  • Embelin ameliorate testosterone-induced prostatic hyperplasia in rats
    M Roopesh, SR Anand Kumar, SB Dhadde, BS Thippeswamy, ...
    Proceedings of the National Academy of Sciences, India Section B: Biological … , 2018
    2018
    Citations: 1
  • Textbook of Industrial Pharmacy
    BNCSB Dhadde
    Studium press New Delhi 1, 523 , 2019
    2019
  • Embelin ameliorate testosterone-induced prostatic hyperplasia in rats.
    MR Marulasiddeshwara Roopesh, SRA Kumar, SB Dhadde, ...
    2018