Dr. Azharuddin Daphedar

@anjuman arts, science and commerce college, vijayapur

Anjuman Arts, Science and Commerce College, Vijayapur

Dr. Azharuddin Daphedar


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https://researchid.co/azhar2887

EDUCATION

M.Sc. Ph.D.

RESEARCH, TEACHING, or OTHER INTERESTS

Environmental Science, General Biochemistry, Genetics and Molecular Biology, General Agricultural and Biological Sciences, Biotechnology
13

Scopus Publications

289

Scholar Citations

9

Scholar h-index

9

Scholar i10-index

Scopus Publications

  • Phyto-derived bismuth and cobalt oxide nanoparticles from Pithecellobium dulce (Roxb.) Benth. leaf extract and assessment of its antioxidant activities: Sustainable development of Bi₂O₃ and Co₃O₄ nanoparticles using Pithecellobium dulce leaf extract and their antioxidant implications
    Firdose Kolar, Azharuddin Daphedar, Megha Vajjaramatti, Gouravva Nyamagoud
    Nanotechnology for Environmental Engineering, 2026
  • Evaluation of Alysicarpus pubescens Y. W. Law for its phytochemical constituents and free radical scavenging activity
    Firdose R. Kolar, Sidanand V. Kambhar, Vaishali S. Kamble, Azharuddin B. Daphedar
    Israel Journal of Plant Sciences, 2025
    This study attempts to provide insights on phytocompounds and antioxidant efficacies of A. pubescens. The study primarily focused on estimation of phenolic content, flavonoid content and antioxidant capacity of different extracts of stem, leaf and inflorescence comparing with standard antioxidants. The results indicated that the amount of phenolics in different plant parts varied from 7.56 to 48.5 mg TAE/g and the amount of flavonoids varied from 0.23 to 0.81 mg QE/g. Among different plant parts, ethanol extract of inflorescence possessed highest amount of phenolics, while aqueous extract of leaf had highest amount of flavonoids as compared to stem. The antioxidant capability of the species as verified by diverse antioxidant assays varied with different plant parts as well as with different solvents used for extraction. Remarkably, all the tested extracts validated a significant free radical scavenging action with the water and ethanol extracts of leaf and inflorescence in most of the test methods. Therefore, water and ethanol were determined to be the most effective solvent systems for extracting antioxidants. The correlation coefficient of phenolics and flavonoids with antioxidant efficacy endorsed the contribution of the phytocompounds to the antioxidant potential. These findings signify that the extracts of A. pubescens possess effective antioxidant properties and can be used to prevent the damage caused by free radicals.
  • Phytofabricated Silver Nanoparticles Derived from Leea crispa Leaf Extract: Antituberculosis and Anticancer Activities
    Tejshwini Doddamani, Balamuralikrishnan Balasubramanian, Siddappa Kakkalameli, Joseph Kadanthottu Sebastian, Manikantan Pappuswamy, Bader O. Almutairi, Mikhlid H. Almutairi, Azharuddin Daphedar
    Bioresources, 2025
    Aqueous extracts of Leea crispa used for producing silver nanoparticles (AgNPs) with the supplementation of the external capping substance, were determined by UV-Visible spectroscopy. The synthesized nanoparticles were examined for their antituberculosis and anticancer activities. The presence of phytoconstituents available for reducing silver ions and to form the AgNPs was confirmed using FTIR analysis. The XRD and TEM examination validated the AgNPs’ spherical particle shape and size of 15 to 85 nm and their face-centered cubic crystal form. Additionally, the FTIR spectrum revealed variation in the band values in the range 1384.0 to 3419.4 cm-1, respectively, and the EDX noted a strong band at 3 keV induced the presence of metallic silver. The AgNPs exhibited comparatively potential anti-tuberculosis activity (0.2 to 100 µg/mL) respectively. Alternatively, various doses of AgNPs, 12.5 to 400 µg/mL documented considerable activity towards the human breast cancer cell lines. The percentage of cell viability increased at 12.5g/mL and declined at 400 ng/mL concentrations of AgNPs solution. The AgNPs synthesized from L. crispa exhibited potential activity against life-threatening tuberculosis and cancer cells.
  • Plant Phenolics Compounds and Stress Management: A Review
    Azharuddin B. Daphedar, Salim Khan, Siddappa Kakkalamel, Tarikere C. Taranath
    Plant Phenolics in Biotic Stress Management, 2024
  • Evaluation of antioxidant and antibacterial activities of silver nanoparticles derived from Limonia acidissima L. fruit extract
    Azharuddin B. Daphedar, Sanjay S. Majani, Praveenkumar J. Kaddipudi, Raveendra B. Hujaratti, Siddappa B. Kakkalmeli, Ali A. Shati, Mohammad Y. Alfaifi, Serag Eldin I. Elbehairi, Chandan Shivamallu, Usha Jinendra, Shiva Prasad Kollur
    Current Research in Green and Sustainable Chemistry, 2024
    In the rapidly expanding field of nanoscience and research, AgNPs and their diverse by-products have been acknowledged as having a green approach. Fruit extract of Limonia acidissima is capable of bio-reducing AgNO3 and stabilizing AgNPs. AgNPs distinctive absorption peak at 417 nm at pH 8 was visible on the UV-Vis spectrophotometer. The fruit extract contained bioactive chemicals, which may be the cause of the AgNPs bio-capping and stabilizing properties, according to Fourier transform infrared (FT-IR) spectroscopy. Using an X-ray diffractometer (XRD) examination, the AgNPs solid crystalline nature and size of 29.05 nm were investigated. Lastly, AFM and HR-TEM studies verified the AgNPs surface morphology, particularly their size and form. The DPPH assay method was used to measure the AgNPs capacity for radical scavenging. As compared to normal ascorbic acid and fruit extract (control), the AgNPs produced from the fruit extract demonstrated good antioxidant effectiveness. To evaluate the antibacterial activity of the AgNPs sample, it was additionally evaluated against E. coli, S. typhi, V. cholera, and S. aureus. With the greatest zone of inhibition and thus the strongest antibacterial activity, S. aureus (12.03 ± 0.043 mm) was the organism that displayed it. On the other hand, the least active strain was V. cholera (9.09 ± 0.013 mm). The data indicates that bio-fabricated silver nanoparticles (AgNPs) exhibited dose-dependent inhibitory efficacy together with a notable zone of inhibition. Additionally, S. aureus was shown to be more effective than V. cholera. Future health and pharmaceutical fields may benefit from the biocompatible method of separating AgNPs from L. acidissima fruit extract.
  • Decolorization of various dyes by microorganisms and green-synthesized nanoparticles: current and future perspective
    Azharuddin B. Daphedar, Siddappa Kakkalameli, Basheerabegum Faniband, Muhammad Bilal, Ram Naresh Bhargava, Luiz Fernando Romanholo Ferreira, Abbas Rahdar, Dummi Mahadevan Gurumurthy, Sikandar I. Mulla
    Environmental Science and Pollution Research, 2023
  • Carissa Carandas L. Fruit Mediated In Vitro Synthesis of Silver Nanoparticles and Their Antioxidant and Antibacterial activities
    Azharuddin B. Daphedar, Tejashwini Basavaprabhu, Viashnavi Nilagar, Annapoorna Waddar
    Al Bahir Journal for Engineering and Pure Sciences, 2023
    Currently, we synthesized silver nanoparticles (AgNPs) from the aqueous fruit extract of Carissa carandas L. and evaluated their antioxidant and antibacterial properties. The UV-visible spectra showed a characteristic absorption peak at 412 nm. The Fourier transform infrared (FTIR) spectroscopy exhibits intense peaks at 3430.23cm-1 and 1625.67cm-1 which indicates the involvement of flavonoids and other functional groups in the biosynthesis, capping, and stabilization of AgNPs. From XRD analysis, the average size of AgNPs was estimated to be 45nm. The biogenic AgNPs were spherical in shape and average size range between 10 to 95nm confirmed by HR-TEM analysis. The fabricated AgNPs by fruit extract were monitored for antioxidant activity using DPPH method. The fruit extract of AgNPs (IC50= 946.22μg/ml) had the highest antioxidant activity against standard ascorbic acid. The antibacterial activity was done using Staphylococcus aureus and Escherichia coli bacterial strains. It was found from the results that the bacterial strain S. aureus had the highest antibacterial activity when compared to E. coli and aqueous fruit extract. Thus, the present study exhibits synergistic antioxidant and antibacterial activity which may explore in future clinical treatment.
  • Biopolymers and Environment
    Siddappa Kakkalameli, Azharuddin B. Daphedar, Basheerabegum Faniband, Swati Sharma, Ashok Kumar Nadda, Luiz Fernando R. Ferreira, Muhammad Bilal, Juliana Heloisa Pinê Américo-Pinheiro, Sikandar I. Mulla
    Springer Series on Polymer and Composite Materials, 2022
  • Eco-Friendly Synthesis of MnO2 Nanorods Using Gmelina arborea Fruit Extract and Its Anticancer Potency Against MCF-7 Breast Cancer Cell Line
    Chandrashekar Srinivasa, SR Santosh Kumar, Sushma Pradeep, Shashanka K Prasad, Ravindra Veerapur, Mohammad Azam Ansari, Mohammad N Alomary, Saad Alghamdi, Mazen Almehmadi, Kavitha GC, Azharuddin B Daphedar, Siddappa B Kakkalameli, Chandan Shivamallu, Shiva Prasad Kollur
    International Journal of Nanomedicine, 2022
    Introduction Cancer disease is known due to its unregulated proliferation of cells that have evolved from the body’s regular cells. The disease develops as a result of epigenetic and genetic modifications, tumor suppressor gene inactivation, and oncogene activation. The present work describes an environmentally benign approach for the synthesis of manganese oxide nanoparticles (MnO2 NPs) using Gmelina arborea fruit extract (GAE) in an aqueous medium. Methods The study evaluated the formation of MnO2 NPs and their anticancer efficacy against MCF-7 breast cancer cell line. Results The formation of MnO2 NPs was confirmed through powder X-ray diffractometer (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM) and high-resolution transmission electron microscopy (HR-TEM). The crystalline nature of as-prepared MnO2 NPs was evident from XRD pattern. The morphology of the material was studied using SEM analysis, which suggested a rod-like nature with an average diameter of 50 nm. Further, the TEM and HR-TEM images confirmed the rod shape of the as-prepared MnO2 NPs with an interplanar distance of 0.271 nm. In addition, the concentric rings from selected area electron diffraction (SAED) analysis show the crystalline nature of the as-prepared material, which further supports the obtained XRD pattern. The anticancer efficacy of MnO2 NPs was evaluated against MCF-7 breast cancer cell line, which showed up to 96% inhibition of the cells at 400 µg/mL concentration. Conclusion Bio-conjugation of MnO2 NPs can provide enough scope for the therapeutic use of Gmelina arborea, assuming appropriate mechanistic evaluations are conducted.
  • Synthesis and characterization of Silver nanoparticles from fruit extract of Michelia Champaca L.: Their antioxidant and antibacterial activity
    International Journal of Nano Dimension, 2020
  • Green synthesis of zinc nanoparticles using leaf extract of Albizia saman (Jacq.) Merr. and their effect on root meristems of Drimia indica (Roxb.) Jessop
    Azharuddin Daphedar, Tarikere C. Taranath
    Caryologia, 2018
  • Characterization and cytotoxic effect of biogenic silver nanoparticles on mitotic chromosomes of Drimia polyantha (Blatt. & McCann) Stearn
    Azharuddin Daphedar, Tarikere C. Taranath
    Toxicology Reports, 2018
  • Biosynthesis of silver nanoparticles by leaf extract of Albizia saman (Jacq.) Merr. and their cytotoxic effect on mitotic chromosomes of Drimia indica (Roxb.) Jessop
    Azharuddin Daphedar, Tarikeri C. Taranath
    Environmental Science and Pollution Research, 2017

RECENT SCHOLAR PUBLICATIONS

  • Phyto-derived bismuth and cobalt oxide nanoparticles from Pithecellobium dulce (Roxb.) Benth. leaf extract and assessment of its antioxidant activities: Sustainable …
    F Kolar, A Daphedar, M Vajjaramatti, G Nyamagoud
    Nanotechnology for Environmental Engineering 11 (2), 60 , 2026
    2026
  • Evaluation of Alysicarpus pubescens YW Law for its phytochemical constituents and free radical scavenging activity
    FR Kolar, SV Kambhar, VS Kamble, AB Daphedar
    Israel Journal of Plant Sciences 1 (aop), 1-10 , 2025
    2025
  • Phytofabricated Silver Nanoparticles Derived from Leea crispa Leaf Extract: Antituberculosis and Anticancer Activities.
    T Doddamani, B Balasubramanian, S Kakkalameli, JK Sebastian, ...
    BioResources 20 (1) , 2025
    2025
  • Comparative examination of phenolic content, flavonoid content, and antioxidant efficacy of Chenopodium album L. and Chenopodium pumilio R. Br.
    ABD Firdose R. Kolar, Sidanand V. Kambhar, Vaishali S. Kamble
    Istanbul Journal of Pharmacy 54 ((2)), 165-174 , 2024
    2024
    Citations: 5
  • Plant phenolics compounds and stress management: A review
    AB Daphedar, S Khan, S Kakkalamel, TC Taranath
    Plant Phenolics in Biotic Stress Management, 481-502 , 2024
    2024
    Citations: 3
  • Evaluation of antioxidant and antibacterial activities of silver nanoparticles derived from Limonia acidissima L. fruit extract
    AB Daphedar, SS Majani, PJ Kaddipudi, RB Hujaratti, SB Kakkalmeli, ...
    Current Research in Green and Sustainable Chemistry 8, 100399 , 2024
    2024
    Citations: 11
  • Biogenic Derived Ag and Zno Nanoparticles Using Couroupita guianensis Aubl. Fruit Extract and its Antibacterial Potential
    PJKFK Azharuddin B Daphedar1 ٭ ,Raveendra B Hujaratti2
    International Journal of Plant Biology & Research 1136 (11(1)), 2-8 , 2023
    2023
  • Clastogenic, Genotoxic Evaluation of Metallic Nanoparticles and their Biological Applications
    SBK Azharuddin B. Daphedar
    Nanotechnology: Current Uses, Future Applications in Biomedicine, 1-17 , 2023
    2023
  • Carissa carandas l. fruit mediated in vitro synthesis of silver nanoparticles and their antioxidant and antibacterial activities
    AB Daphedar, T Basavaprabhu, V Nilagar, A Waddar
    Al-Bahir Journal for engineering and Pure Sciences 2 (2), 1 , 2023
    2023
    Citations: 6
  • Biopolymers and Environment
    S Kakkalameli, AB Daphedar, B Faniband, S Sharma, AK Nadda, ...
    Biopolymers: Recent Updates, Challenges and Opportunities, 19 , 2022
    2022
    Citations: 17
  • Eco-Friendly Synthesis of MnO2 Nanorods Using Gmelina arborea Fruit Extract and Its Anticancer Potency Against MCF-7 Breast Cancer Cell Line
    A Daphedar
    International Journal of Nanomedicine 17, 901-907 , 2022
    2022
    Citations: 42
  • Decolorization of various dyes by microorganisms and green-synthesized nanoparticles: current and future perspective
    ABDSKBFMBRNBLFRFARDMGSI Mulla
    Environmental science and Pollution Research , 2022
    2022
    Citations: 40
  • Genotoxic assay of silver and zinc oxide nanoparticles synthesized by leaf extract of Garcinia livingstonei T. Anderson: A comparative study
    AB Daphedar, SB Kakkalameli, G Melappa, TC Taranath, C Srinivasa, ...
    Pharmacogn. Mag 17, 114 , 2021
    2021
    Citations: 9
  • Bioactive Molecules and their Role in the Eradication of Infectious Diseases: Current and Future Prospective
    SIM Azharuddin B. Daphedar, Siddappa Kakkalmeli
    ISBN: 978-1-63278-998-3, Published by Innovationinfoebooks Heathrow Stockley … , 2021
    2021
  • Effect of Chromium on morphological and biochemical responses on aquatic macrophyte Pistia stratiotes L.(Water lettuce)
    S Kakkalameli, A Daphedar
    International Journal of Pharmaceutical Sciences and Research , 2021
    2021
    Citations: 1
  • Synthesis and characterization of Silver nanoparticles from fruit extract of Michelia Champaca L.: Their antioxidant and antibacterial activity
    A Daphedar
    International Journal of Nano Dimension , 2020
    2020
    Citations: 13
  • Biomimetic Synthesis and Characterization of Silver Nanoparticles Synthesized by Leaf Extract of Bridellia stipularis L Blume and Evaluation of their Effect on Mitotic …
    A Daphedar
    Journal of Nanosciences: Current Research 4 (12), 09 , 2019
    2019
    Citations: 2
  • Azolla filiculoides Lam. as a phytotool for remediation of heavy metals from sewage
    SB Kakkalameli, A Daphedar, N Hulakoti, BN Patil, TC Taranath
    International Journal of Pharmaceutical, Chemical & Biological Sciences 8 (3) , 2018
    2018
    Citations: 14
  • Green synthesis of zinc nanoparticles using leaf extract of Albizia saman (Jacq.) Merr. and their effect on root meristems of Drimia indica (Roxb.) Jessop
    A Daphedar, TC Taranath
    Caryologia 71 (2), 93-102 , 2018
    2018
    Citations: 47
  • Characterization and cytotoxic effect of biogenic silver nanoparticles on mitotic chromosomes of Drimia polyantha (Blatt. & McCann) Stearn
    A Daphedar, TC Taranath
    Toxicology Reports 5, 910-918 , 2018
    2018
    Citations: 57

MOST CITED SCHOLAR PUBLICATIONS

  • Characterization and cytotoxic effect of biogenic silver nanoparticles on mitotic chromosomes of Drimia polyantha (Blatt. & McCann) Stearn
    A Daphedar, TC Taranath
    Toxicology Reports 5, 910-918 , 2018
    2018
    Citations: 57
  • Green synthesis of zinc nanoparticles using leaf extract of Albizia saman (Jacq.) Merr. and their effect on root meristems of Drimia indica (Roxb.) Jessop
    A Daphedar, TC Taranath
    Caryologia 71 (2), 93-102 , 2018
    2018
    Citations: 47
  • Eco-Friendly Synthesis of MnO2 Nanorods Using Gmelina arborea Fruit Extract and Its Anticancer Potency Against MCF-7 Breast Cancer Cell Line
    A Daphedar
    International Journal of Nanomedicine 17, 901-907 , 2022
    2022
    Citations: 42
  • Decolorization of various dyes by microorganisms and green-synthesized nanoparticles: current and future perspective
    ABDSKBFMBRNBLFRFARDMGSI Mulla
    Environmental science and Pollution Research , 2022
    2022
    Citations: 40
  • Biosynthesis of silver nanoparticles by leaf extract of Albizia saman (Jacq.) Merr. and their cytotoxic effect on mitotic chromosomes of Drimia indica (Roxb.) Jessop
    A Daphedar, TC Taranath
    Environmental Science and Pollution Research 24 (33), 25861-25869 , 2017
    2017
    Citations: 19
  • Biopolymers and Environment
    S Kakkalameli, AB Daphedar, B Faniband, S Sharma, AK Nadda, ...
    Biopolymers: Recent Updates, Challenges and Opportunities, 19 , 2022
    2022
    Citations: 17
  • Azolla filiculoides Lam. as a phytotool for remediation of heavy metals from sewage
    SB Kakkalameli, A Daphedar, N Hulakoti, BN Patil, TC Taranath
    International Journal of Pharmaceutical, Chemical & Biological Sciences 8 (3) , 2018
    2018
    Citations: 14
  • Synthesis and characterization of Silver nanoparticles from fruit extract of Michelia Champaca L.: Their antioxidant and antibacterial activity
    A Daphedar
    International Journal of Nano Dimension , 2020
    2020
    Citations: 13
  • Evaluation of antioxidant and antibacterial activities of silver nanoparticles derived from Limonia acidissima L. fruit extract
    AB Daphedar, SS Majani, PJ Kaddipudi, RB Hujaratti, SB Kakkalmeli, ...
    Current Research in Green and Sustainable Chemistry 8, 100399 , 2024
    2024
    Citations: 11
  • Genotoxic assay of silver and zinc oxide nanoparticles synthesized by leaf extract of Garcinia livingstonei T. Anderson: A comparative study
    AB Daphedar, SB Kakkalameli, G Melappa, TC Taranath, C Srinivasa, ...
    Pharmacogn. Mag 17, 114 , 2021
    2021
    Citations: 9
  • Carissa carandas l. fruit mediated in vitro synthesis of silver nanoparticles and their antioxidant and antibacterial activities
    AB Daphedar, T Basavaprabhu, V Nilagar, A Waddar
    Al-Bahir Journal for engineering and Pure Sciences 2 (2), 1 , 2023
    2023
    Citations: 6
  • Comparative examination of phenolic content, flavonoid content, and antioxidant efficacy of Chenopodium album L. and Chenopodium pumilio R. Br.
    ABD Firdose R. Kolar, Sidanand V. Kambhar, Vaishali S. Kamble
    Istanbul Journal of Pharmacy 54 ((2)), 165-174 , 2024
    2024
    Citations: 5
  • Plant phenolics compounds and stress management: A review
    AB Daphedar, S Khan, S Kakkalamel, TC Taranath
    Plant Phenolics in Biotic Stress Management, 481-502 , 2024
    2024
    Citations: 3
  • Cytotoxic and Genotoxic effect of biofabricated zinc nanoparticles on mitotic chromosomes of Drimia polyantha (Roxb.) Jessop.
    A Daphedar, TC Taranath
    International Journal of Pharmaceutical, Chemical & Biological Sciences 8 (1) , 2018
    2018
    Citations: 3
  • Biomimetic Synthesis and Characterization of Silver Nanoparticles Synthesized by Leaf Extract of Bridellia stipularis L Blume and Evaluation of their Effect on Mitotic …
    A Daphedar
    Journal of Nanosciences: Current Research 4 (12), 09 , 2019
    2019
    Citations: 2
  • Effect of Chromium on morphological and biochemical responses on aquatic macrophyte Pistia stratiotes L.(Water lettuce)
    S Kakkalameli, A Daphedar
    International Journal of Pharmaceutical Sciences and Research , 2021
    2021
    Citations: 1
  • Phyto-derived bismuth and cobalt oxide nanoparticles from Pithecellobium dulce (Roxb.) Benth. leaf extract and assessment of its antioxidant activities: Sustainable …
    F Kolar, A Daphedar, M Vajjaramatti, G Nyamagoud
    Nanotechnology for Environmental Engineering 11 (2), 60 , 2026
    2026
  • Evaluation of Alysicarpus pubescens YW Law for its phytochemical constituents and free radical scavenging activity
    FR Kolar, SV Kambhar, VS Kamble, AB Daphedar
    Israel Journal of Plant Sciences 1 (aop), 1-10 , 2025
    2025
  • Phytofabricated Silver Nanoparticles Derived from Leea crispa Leaf Extract: Antituberculosis and Anticancer Activities.
    T Doddamani, B Balasubramanian, S Kakkalameli, JK Sebastian, ...
    BioResources 20 (1) , 2025
    2025
  • Biogenic Derived Ag and Zno Nanoparticles Using Couroupita guianensis Aubl. Fruit Extract and its Antibacterial Potential
    PJKFK Azharuddin B Daphedar1 ٭ ,Raveendra B Hujaratti2
    International Journal of Plant Biology & Research 1136 (11(1)), 2-8 , 2023
    2023