Assistant Professor Dr.Mohammed Ayyed Najm

@ruc.edu.iq

Al-Rafidain University College / Pharmacy Department
Al-Rafidain University College

Assistant Professor Dr.Mohammed Ayyed Najm


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https://researchid.co/assis.prof.dr.mohammedayyednajm
 Assistant Professor ( at Al-Rafidain University College / Pharmacy Department / Baghdad – Iraq (2020 – present).
 Senior Lecturer ( at Al-Rafidain University College / Dentistry & Pharmacy Department / Baghdad – Iraq (2015 – 2020).
 Lecturer Assistance at Al-Iraqia College of Medicine / Baghdad – Iraq (2011-2013).
 Lecturer Assistance at Al-Anbar College of Medicine / Al-Ramadi – Iraq (2010-2011).
 Teaching Assistance at Baghdad College of Pharmacy / Baghdad – Iraq (2006-2008).

EDUCATION

 Ph.D. in Genetic Engineering & Biotechnology / King’s College of London & Baghdad University - 2015.
 Master Degree in Genetic Engineering & Biotechnology / Baghdad University - 2010.
 Bachelor of Pharmacy / Baghdad University - 2005.

RESEARCH INTERESTS

Pharmaceutical Biotechnology, Gene Therapy, Molecular Genetics, Molecular Biology, Genetics.
13

Scopus Publications

140

Scholar Citations

5

Scholar h-index

2

Scholar i10-index

Scopus Publications

  • HEMATOLOGICAL PARAMETERS IN HEPATOCELLULAR CARCINOMA AND microRNA-223 GENE ASSOCIATED WITH HEPATITIS VIRUS IN LOCAL AREA
    M. S. Al-Janaby, R. H. Abdujaleel, M. A. Najm, Rana Talib Mohsen, A. K. Alalwani
    Russian Journal of Infection and Immunity, 2026
    Background. Hepatocyte function may be altered by chronic HBV and HCV infections through similar mechanisms that influence the onset of hepatocellular cancer. This current work points to examine the function of microRNA-223 in Iraqi hepatocellular carcinoma (HCC) patients induced by hepatitis virus. MicroRNA-223 served as calibrator to explores its evaluate disease progression and diagnosis. Materials and methods. Blood samples were then drawn from 20 people (males and females and different ages), some of them were latterly diagnosed with HCC. these blood samples were used later for molecular study to find target gene expression. Results. The importance of HCV, HBV, and liver cancer was examined in this study, along with the drop in research and studies conducted in Iraq. Those who got treatment had somewhat higher levels of microRNA-223 countenance, whereas those who were diagnosed early and did not get treatment had lower levels. MicroRNA-223 appearance stages were meaningfully lower in the first phase of hepatitis samples than in standard samples (p 0.0001), which may indicate that microRNA-223 can be used as a biomarker to monitor conduct effectiveness. It is recommended that more research done in this area to help in diagnosis. Conclusion. MicroRNAs are an essential tool for early diagnosis and for monitoring the onset and progression of disease due to their great specificity and reliability. all results hat HCC patients with HBV and HCV expressed miR-223 at lower levels than healthy controls. Some hematological and parameters differed significantly from those in the control group.
  • Expression alterations of KRAS gene associated with AgNPs
    Agricultural Biotechnology Journal, 2025
  • Association Between Silver Nanoparticle Dose and Brain or Renal NF-κB Gene Expression
    Journal of Nanostructures, 2025
  • Comparison of double dose of Paracetamol tablets 500mg with one Paracetamol tablet 1000mg
    Baraa Daghman, Nisrin Kaddar, Mohammed Ayyed Najm, Hala Barakat
    Research Journal of Pharmacy and Technology, 2024
    Various geometrical shapes of paracetamol tablets are available, which play an important effect on the speed and quantity of drug release and swallow ability. Patients with swallowing disorders experience difficulties taking large dose (1000mg), which may lead to take two smaller tablets 500mg. This study purposes to investigate the impact of doubling dose and different geometrics on drug release, depending on dissolution test and surface area to volume ratio (SA/V). First, all the studied companies were confirmed to the required constitutional specifications. Then, the dimensions of different shapes of tablets and SA/V ratio were calculated by using Solid Works program. Finally, the dissolution test was performed in a medium of phosphate buffer (pH=5.8) for 30 minutes. All tablets were accepted in term of uniformity of content and weight and showed acceptable friability, with suitable hardness and the disintegration time was less than 30 minutes. After half an hour of beginning the dissolution test, over 80% of the paracetamol from all the tablets examined was found to have been released. The release rates were approximately constant for the various shapes of tablets with the same rate of SA/V. Drug release from two tablets of 500mg was faster than that from one tablet of 1000mg, this offers a therapeutic benefit to achieve the analgesic effect more quickly.
  • Evaluate the potential utilisation of B3S monolayer as a novel formaldehyde gas sensor
    Munther Abosaooda, Hala Bahir, Nawras Ali Salman, Sarah Kamil Abbood, Laith Yassen Qassem, et al.
    Molecular Physics, 2024
  • Photocatalytic Organic Contaminant Degradation of Green Synthesized ZrO2 NPs and Their Antibacterial Activities
    Parvathiraja Chelliah, Saikh Mohammad Wabaidur, Hari Prapan Sharma, Hasan Sh. Majdi, Drai Ahmed Smait, et al.
    Separations, 2023
    The green synthesis of metal oxide nanoparticles is an efficient, simple, and chemical-free method of producing nanoparticles. The present work reports the synthesis of Murraya koenigii-mediated ZrO2 nanoparticles (ZrO2 NPs) and their applications as a photocatalyst and antibacterial agent. Capping and stabilization of metal oxide nanoparticles were achieved by using Murraya koenigii leaf extract. The optical, structural, and morphological valance of the ZrO2 NPs were characterized using UV-DRS, FTIR, XRD, and FESEM with EDX, TEM, and XPS. An XRD analysis determined that ZrO2 NPs have a monoclinic structure and a crystallite size of 24 nm. TEM and FESEM morphological images confirm the spherical nature of ZrO2 NPs, and their distributions on surfaces show lower agglomerations. ZrO2 NPs showed high optical absorbance in the UV region and a wide bandgap indicating surface oxygen vacancies and charge carriers. The presence of Zr and O elements and their O=Zr=O bonds was categorized using EDX and FTIR spectroscopy. The plant molecules’ interface, bonding, binding energy, and their existence on the surface of ZrO2 NPs were established from XPS analysis. The photocatalytic degradation of methylene blue using ZrO2 NPs was examined under visible light irradiation. The 94% degradation of toxic MB dye was achieved within 20 min. The antibacterial inhibition of ZrO2 NPs was tested against S. aureus and E. coli pathogens. Applications of bio-synthesized ZrO2 NPs including organic substance removal, pathogenic inhibitor development, catalysis, optical, and biomedical development were explored.
  • Nanotechnology at the Molecular Level
    Gulboy Abdolmajeed Nasir, Iman Abbas Khudhair, Mohammed Ayyed Najm, Huda Musleh Mahmood
    Al Rafidain Journal of Medical Sciences, 2022
    Materials with external dimensions of one or more nanometers are referred to as nanomaterials. These structures result from a number of manufacturing processes. They are used in many industries, including pharmaceuticals, which is the most significant one. Numerous variables, including size, shape, surface morphology, crystallinity, solubility, etc., affect physical properties. While new physical and chemical processes are being created constantly, the biological method is the ideal strategy for synthesizing nanoparticles since it is straightforward, safe, and economical. Different kinds of nanoparticles can be metabolically synthesized by a wide variety of biological sources, including plants, bacteria, fungi, and yeast. There are many biomolecules, including proteins and coenzymes, that can change the metal salts into the necessary nanoparticles. There were numerous techniques for creating RNA nanoparticles. The first tactic makes use of the natural RNA nanoparticles' collection process. The second strategy entails extending the widely used DNA nanotechnology approach to the field of RNA; the third strategy uses computational methods to produce RNA nanoparticles; and the fourth strategy uses preexisting RNA structures or those with known properties as fundamental building blocks in the synthesis of RNA nanoparticles. The purpose of this paper is to give an overview of the significance of RNA nanotechnology, a novel idea in the field of nanotechnology.
  • Genetic diversity of three medicinal plants of apiaceous family
    Systematic Reviews in Pharmacy, 2020
  • Correlating schizophrenia with DRD3 Ser9Gly or HTR2 receptor gene variants by using RFLP method
    Indian Journal of Forensic Medicine and Toxicology, 2020
  • Detect the infection with rubella virus and toxoplasmosis in pregnancy causes suffering from early abortion by using real time PCR
    Medico Legal Update, 2020
  • The effect of silver nanoparticles on braf gene expression
    Systematic Reviews in Pharmacy, 2020
  • Association of polymorphism GST1 gene and antioxidant status, and interleukin-17 of colorectal cancer Iraqi patients
    Aqeel Shakir Mahmood, Shireen Hamid Farhan, Mohammed Ayyed Najm
    Indian Journal of Forensic Medicine and Toxicology, 2019
  • Evaluation of antioxidant (GSH, CAT, SOD) and MDA in Iraqi women with breast cancer
    Journal of Global Pharma Technology, 2019

RECENT SCHOLAR PUBLICATIONS

  • Hematological parameters in hepatocellular carcinoma AND microRNA-223 gene associated with Hepatitis virus in local area
    MS Al-Janaby, RH Abdujaleel, MA Najm, RT Mohsen, AK Alalwani
    Russian Journal of Infection and Immunity 15 (6), 1137-1142 , 2025
    2025.0
  • Expression Alterations of KRAS Gene Associated with AgNPs
    M Ayyed Najm, G Abdolmajeed Nasir, H Musleh Mahmood
    Agricultural Biotechnology Journal 17 (2), 217-236 , 2025
    2025.0
    Citations: 1
  • Association between silver nanoparticle dose and brain or renal nf-κb gene expression
    G A Nasir, M A Najm, HM Mahmood
    Journal of Nanostructures 15 (1), 249-254 , 2025
    2025.0
    Citations: 4
  • Comparison of double dose of Paracetamol tablets 500mg with one Paracetamol tablet 1000mg
    B Daghman, N Kaddar, MA Najm, H Barakat
    Research Journal of Pharmacy and Technology 17 (10), 4671-4676 , 2024
    2024.0
    Citations: 3
  • Evaluate the potential utilisation of B 3 S monolayer as a novel formaldehyde gas sensor
    M Abosaooda, H Bahir, N Ali Salman, S Kamil Abbood, L Yassen Qassem, ...
    Molecular Physics 122 (12), e2294154 , 2024
    2024.0
    Citations: 3
  • Photocatalytic Organic Contaminant Degradation of Green Synthesized ZrO 2 NPs and Their Antibacterial Activities
    P Chelliah, SM Wabaidur, HP Sharma, HS Majdi, DA Smait, MA Najm, ...
    Separations 10 (3), 156 , 2023
    2023.0
    Citations: 81
  • Nanotechnology at the molecular level
    GA Nasir, IA Khudhair, MA Najm, HM Mahmood
    Al-Rafidain Journal of Medical Sciences (ISSN 2789-3219) 3, 71-74 , 2022
    2022.0
    Citations: 7
  • Does Brain or Renal Expression of KRAS be influenced by Silver-Nanoparticles?
    MA Najm, GA Nasir, HM Mahmood.
    Arab Journal for Scientific Publishing (AJSP) / Special Edition , 2022
    2022.0
  • Genetic Diversity of Three Medicinal Plants of Apiaceous Family.
    OH Hazim, MA Najm, ZO Ibraheem
    Systematic Reviews in Pharmacy 11 (8) , 2020
    2020.0
    Citations: 3
  • Correlating Schizophrenia with DRD3 Ser9Gly or HTR2 Receptor Gene Variants by using RFLP Method
    MA Najm, ZSM Al–Hadeithi, ATA Salih
    Indian Journal of Forensic Medicine and Toxicology 14 (3), 2038-2043 , 2020
    2020.0
    Citations: 2
  • Detect the Infection with Rubella Virus and Toxoplasmosis in Pregnancy Cases Suffering from Early Abortion by Using Real Time PCR
    HMF Mohammed Ayyed Najm, Hadeel Abdelelah Abdel Razaak
    Medico Legal Update 20 (No. 1), 397–402 , 2020
    2020.0
    Citations: 5
  • The effect of silver nanoparticles on BRAF gene expression
    G Nasir
    Systematic Reviews in Pharmacy , 2020
    2020.0
    Citations: 14
  • Association of polymorphism GST1 gene and antioxidant status, and interleukin-17 of colorectal cancer Iraqi patients
    AS Mahmood, SH Farhan, MA Najm
    Indian Journal of Forensic Medicine & Toxicology 13 (4), 548 , 2019
    2019.0
    Citations: 3
  • Evaluation of antioxidant (GSH, CAT, SOD) and MDA in Iraqi women with breast cancer
    MA Najm, WR Alfatlawi, RO Saleh, SM Kadhim Al Taie
    Journal of Global Pharma Technology 11 (7), 107-110 , 2019
    2019.0
    Citations: 5
  • The Diagnostic and Prognostic Values of NCR1 and NCR3 Genes in Iraqi Breast Cancer Women
    MA Najm
    Iraqi Journal of Cancer and Medical Genetics 9 (1) , 2016
    2016.0
  • The diagnostic and prognostic values of FOXP3 gene in Iraqi breast cancer women
    MA Najm
    Iraqi Journal of Cancer and Medical Genetics 9 (1) , 2016
    2016.0
    Citations: 2
  • The role of interleukin-10 in women with metastatic invasive ductal carcinoma
    AN Althwani, MA Najm
    Journal of the Faculty of Medicine Baghdad 53 (3), 289-292 , 2011
    2011.0
    Citations: 4
  • The importance of CA15-3 in the follow up of Metastatic Invasive Ductal Carcinoma Iraqi Women
    AN Althwani, MA Najm
    Iraqi Journal of Cancer and Medical Genetics 4 (1), 7-10 , 2011
    2011.0
    Citations: 3
  • The Role of Interleukin-10 in Women with Metastatic Invasive Ductal Carcinoma
    MA Najm, AN Althwani
    Journal of the Faculty of Medicine 53 (3) , 2011
    2011.0
  • Does Brain or Renal Expression of KRAS be influenced by Silver-Nanoparticles?
    MA Najm, GA Nasir, HM Mahmood
    Arab Journal for Scientific Publishing (AJSP)/Special Edition ISSN 2663, 5798 , 0

MOST CITED SCHOLAR PUBLICATIONS

  • Photocatalytic Organic Contaminant Degradation of Green Synthesized ZrO 2 NPs and Their Antibacterial Activities
    P Chelliah, SM Wabaidur, HP Sharma, HS Majdi, DA Smait, MA Najm, ...
    Separations 10 (3), 156 , 2023
    2023.0
    Citations: 81
  • The effect of silver nanoparticles on BRAF gene expression
    G Nasir
    Systematic Reviews in Pharmacy , 2020
    2020.0
    Citations: 14
  • Nanotechnology at the molecular level
    GA Nasir, IA Khudhair, MA Najm, HM Mahmood
    Al-Rafidain Journal of Medical Sciences (ISSN 2789-3219) 3, 71-74 , 2022
    2022.0
    Citations: 7
  • Detect the Infection with Rubella Virus and Toxoplasmosis in Pregnancy Cases Suffering from Early Abortion by Using Real Time PCR
    HMF Mohammed Ayyed Najm, Hadeel Abdelelah Abdel Razaak
    Medico Legal Update 20 (No. 1), 397–402 , 2020
    2020.0
    Citations: 5
  • Evaluation of antioxidant (GSH, CAT, SOD) and MDA in Iraqi women with breast cancer
    MA Najm, WR Alfatlawi, RO Saleh, SM Kadhim Al Taie
    Journal of Global Pharma Technology 11 (7), 107-110 , 2019
    2019.0
    Citations: 5
  • Association between silver nanoparticle dose and brain or renal nf-κb gene expression
    G A Nasir, M A Najm, HM Mahmood
    Journal of Nanostructures 15 (1), 249-254 , 2025
    2025.0
    Citations: 4
  • The role of interleukin-10 in women with metastatic invasive ductal carcinoma
    AN Althwani, MA Najm
    Journal of the Faculty of Medicine Baghdad 53 (3), 289-292 , 2011
    2011.0
    Citations: 4
  • Comparison of double dose of Paracetamol tablets 500mg with one Paracetamol tablet 1000mg
    B Daghman, N Kaddar, MA Najm, H Barakat
    Research Journal of Pharmacy and Technology 17 (10), 4671-4676 , 2024
    2024.0
    Citations: 3
  • Evaluate the potential utilisation of B 3 S monolayer as a novel formaldehyde gas sensor
    M Abosaooda, H Bahir, N Ali Salman, S Kamil Abbood, L Yassen Qassem, ...
    Molecular Physics 122 (12), e2294154 , 2024
    2024.0
    Citations: 3
  • Genetic Diversity of Three Medicinal Plants of Apiaceous Family.
    OH Hazim, MA Najm, ZO Ibraheem
    Systematic Reviews in Pharmacy 11 (8) , 2020
    2020.0
    Citations: 3
  • Association of polymorphism GST1 gene and antioxidant status, and interleukin-17 of colorectal cancer Iraqi patients
    AS Mahmood, SH Farhan, MA Najm
    Indian Journal of Forensic Medicine & Toxicology 13 (4), 548 , 2019
    2019.0
    Citations: 3
  • The importance of CA15-3 in the follow up of Metastatic Invasive Ductal Carcinoma Iraqi Women
    AN Althwani, MA Najm
    Iraqi Journal of Cancer and Medical Genetics 4 (1), 7-10 , 2011
    2011.0
    Citations: 3
  • Correlating Schizophrenia with DRD3 Ser9Gly or HTR2 Receptor Gene Variants by using RFLP Method
    MA Najm, ZSM Al–Hadeithi, ATA Salih
    Indian Journal of Forensic Medicine and Toxicology 14 (3), 2038-2043 , 2020
    2020.0
    Citations: 2
  • The diagnostic and prognostic values of FOXP3 gene in Iraqi breast cancer women
    MA Najm
    Iraqi Journal of Cancer and Medical Genetics 9 (1) , 2016
    2016.0
    Citations: 2
  • Expression Alterations of KRAS Gene Associated with AgNPs
    M Ayyed Najm, G Abdolmajeed Nasir, H Musleh Mahmood
    Agricultural Biotechnology Journal 17 (2), 217-236 , 2025
    2025.0
    Citations: 1
  • Hematological parameters in hepatocellular carcinoma AND microRNA-223 gene associated with Hepatitis virus in local area
    MS Al-Janaby, RH Abdujaleel, MA Najm, RT Mohsen, AK Alalwani
    Russian Journal of Infection and Immunity 15 (6), 1137-1142 , 2025
    2025.0
  • Does Brain or Renal Expression of KRAS be influenced by Silver-Nanoparticles?
    MA Najm, GA Nasir, HM Mahmood.
    Arab Journal for Scientific Publishing (AJSP) / Special Edition , 2022
    2022.0
  • The Diagnostic and Prognostic Values of NCR1 and NCR3 Genes in Iraqi Breast Cancer Women
    MA Najm
    Iraqi Journal of Cancer and Medical Genetics 9 (1) , 2016
    2016.0
  • The Role of Interleukin-10 in Women with Metastatic Invasive Ductal Carcinoma
    MA Najm, AN Althwani
    Journal of the Faculty of Medicine 53 (3) , 2011
    2011.0
  • Does Brain or Renal Expression of KRAS be influenced by Silver-Nanoparticles?
    MA Najm, GA Nasir, HM Mahmood
    Arab Journal for Scientific Publishing (AJSP)/Special Edition ISSN 2663, 5798 , 0