Functionalization of iron oxide nanoparticles with biosurfactants and biocompatibility studies J. Sangeetha, Susha Thomas, J. Arutchelvi, Mukesh Doble, John Philip Journal of Biomedical Nanotechnology, 2013 We present methodologies to functionalize iron oxide (Fe3O4) nanoparticles with biosurfactants and biocompatibility results. Positively charged Fe3O4 nanoparticles of average hydrodynamic size -26 nm is functionalized with four different molecules of interest, viz., surfactin, rhamnolipid, polyethylene glycol (PEG) and dextran. The functionalization results in dramatic alterations in surface potential and hydrodynamic size due to the presence of coated moieties on the nanoparticle interface. The Fourier transform infrared spectroscopy and thermogravimetric analysis confirm the presence of adsorbed moieties on nanoparticles. The phase contrast microscopy studies show the formation of reversible chains of functionalized nanoparticles under an external magnetic field. Cell viability studies using L929 mouse fibroblast cell line show that pure surfactin, rhamnolipid and dextran exhibit cytotoxicity with increase in concentration, whereas, pure PEG exhibit biocompatibility at different concentrations. Accordingly, surfactin and rhamnolipid coated nanoparticles are found to be cytotoxic with increase in concentration and PEG coated nanoparticles are found to be biocompatible. Dextran coated nanoparticles do not exhibit significant increase in biocompatibility.
Mannosylerythritol lipids: A review Joseph Irudayaraj Arutchelvi, Sumit Bhaduri, Parasu Veera Uppara, Mukesh Doble Journal of Industrial Microbiology and Biotechnology, 2008 Mannosylerythritol lipids (MELs) are surface active compounds that belong to the glycolipid class of biosurfactants (BSs). MELs are produced by Pseudozyma sp. as a major component while Ustilago sp. produces them as a minor component. Although MELs have been known for over five decades, they recently regained attention due to their environmental compatibility, mild production conditions, structural diversity, self-assembling properties and versatile biochemical functions. In this review, the MEL producing microorganisms, the production conditions, their applications, their diverse structures and self-assembling properties are discussed. The biosynthetic pathways and the regulatory mechanisms involved in the production of MEL are also explained here.
Biodegradation of polyethylene and polypropylene Indian Journal of Biotechnology, 2008
RECENT SCHOLAR PUBLICATIONS
Self-assembly of surfactin in aqueous solution: role of divalent counterions J Arutchelvi, J Sangeetha, J Philip, M Doble Colloids and Surfaces B: Biointerfaces 116, 396-402 , 2014 2014 Citations: 81
Functionalization of iron oxide nanoparticles with biosurfactants and biocompatibility studies J Sangeetha, S Thomas, J Arutchelvi, M Doble, J Philip Journal of biomedical nanotechnology 9 (5), 751-764 , 2013 2013 Citations: 46
Process optimization for the production of rhamnolipid and formation of biofilm by Pseudomonas aeruginosa CPCL on polypropylene J Arutchelvi, C Joseph, M Doble Biochemical engineering journal 56 (1-2), 37-45 , 2011 2011 Citations: 36
Mannosylerythritol lipids: microbial production and their applications J Arutchelvi, M Doble Biosurfactants: from genes to applications, 145-177 , 2010 2010 Citations: 39
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Degradation of unpretreated and thermally pretreated polypropylene by soil consortia A Arkatkar, J Arutchelvi, S Bhaduri, PV Uppara, M Doble International Biodeterioration & Biodegradation 63 (1), 106-111 , 2009 2009 Citations: 284
Mannosylerythritol lipids: a review JI Arutchelvi, S Bhaduri, PV Uppara, M Doble Journal of Industrial Microbiology and Biotechnology 35 (12), 1559-1570 , 2008 2008 Citations: 258
Biodegradation of polyethylene and polypropylene J Arutchelvi, M Sudhakar, A Arkatkar, M Doble, S Bhaduri, PV Uppara Indian Journal of Biotechnology 7 (1), 9 , 2008 2008 Citations: 652
MOST CITED SCHOLAR PUBLICATIONS
Biodegradation of polyethylene and polypropylene J Arutchelvi, M Sudhakar, A Arkatkar, M Doble, S Bhaduri, PV Uppara Indian Journal of Biotechnology 7 (1), 9 , 2008 2008 Citations: 652
Degradation of unpretreated and thermally pretreated polypropylene by soil consortia A Arkatkar, J Arutchelvi, S Bhaduri, PV Uppara, M Doble International Biodeterioration & Biodegradation 63 (1), 106-111 , 2009 2009 Citations: 284
Mannosylerythritol lipids: a review JI Arutchelvi, S Bhaduri, PV Uppara, M Doble Journal of Industrial Microbiology and Biotechnology 35 (12), 1559-1570 , 2008 2008 Citations: 258
Approaches to enhance the biodegradation of polyolefins A Arkatkar, J Arutchelvi, M Sudhakar, S Bhaduri, PV Uppara, M Doble The Open Environmental Engineering Journal 2 (1), 68-80 , 2009 2009 Citations: 133
Self-assembly of surfactin in aqueous solution: role of divalent counterions J Arutchelvi, J Sangeetha, J Philip, M Doble Colloids and Surfaces B: Biointerfaces 116, 396-402 , 2014 2014 Citations: 81
Characterization of glycolipid biosurfactant from Pseudomonas aeruginosa CPCL isolated from petroleum‐contaminated soil J Arutchelvi, M Doble Letters in applied microbiology 51 (1), 75-82 , 2010 2010 Citations: 61
Functionalization of iron oxide nanoparticles with biosurfactants and biocompatibility studies J Sangeetha, S Thomas, J Arutchelvi, M Doble, J Philip Journal of biomedical nanotechnology 9 (5), 751-764 , 2013 2013 Citations: 46
Mannosylerythritol lipids: microbial production and their applications J Arutchelvi, M Doble Biosurfactants: from genes to applications, 145-177 , 2010 2010 Citations: 39
Process optimization for the production of rhamnolipid and formation of biofilm by Pseudomonas aeruginosa CPCL on polypropylene J Arutchelvi, C Joseph, M Doble Biochemical engineering journal 56 (1-2), 37-45 , 2011 2011 Citations: 36
Production and characterization of biosurfactant from Bacillus subtilis YB7 J Arutchelvi, M Doble JOURNAL OF APPLIED SCIENCE 9 (17), 3151-3155 , 2009 2009 Citations: 33